Summary: Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Top Publications

  1. ncbi Multivitamin-multimineral supplements: who uses them?
    Cheryl L Rock
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0901, USA
    Am J Clin Nutr 85:277S-279S. 2007
  2. ncbi A safe strategy for addition of vitamins and minerals to foods
    S E Rasmussen
    Danish Institute for Food and Veterinary Research, 19 Mørkhøj Bygade, 2860, Søborg, Denmark
    Eur J Nutr 45:123-35. 2006
  3. ncbi Mineral metabolism, mortality, and morbidity in maintenance hemodialysis
    Geoffrey A Block
    Denver Nephrology Associates, Denver Colorado, USA
    J Am Soc Nephrol 15:2208-18. 2004
  4. ncbi Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease
    Adrian Covic
    Dialysis and Renal Transplantation Center, C I Parhon University Hospital and University of Medicine Gr T Popa Iasi, Blvd Carol I Nr 50, Iasi, 700503, Romania
    Nephrol Dial Transplant 24:1506-23. 2009
  5. pmc Dietary supplement use is associated with higher intakes of minerals from food sources
    Regan L Bailey
    Office of Dietary Supplements, NIH, Bethesda, MD 20892 7517, USA
    Am J Clin Nutr 94:1376-81. 2011
  6. ncbi Progression of aortic calcification is associated with disorders of mineral metabolism and mortality in chronic dialysis patients
    Marlies Noordzij
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Nephrol Dial Transplant 26:1662-9. 2011
  7. ncbi Metals, minerals and microbes: geomicrobiology and bioremediation
    Geoffrey Michael Gadd
    Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    Microbiology 156:609-43. 2010
  8. pmc Materials become insensitive to flaws at nanoscale: lessons from nature
    Huajian Gao
    Max Planck Institute for Metals Research, Heisenbergstrasse 3, D 70569 Stuttgart, Germany
    Proc Natl Acad Sci U S A 100:5597-600. 2003
  9. pmc Cooperative deformation of mineral and collagen in bone at the nanoscale
    Himadri S Gupta
    Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, D 144 24 Potsdam, Germany
    Proc Natl Acad Sci U S A 103:17741-6. 2006
  10. pmc Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males
    David O Kennedy
    Brain, Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK
    Psychopharmacology (Berl) 211:55-68. 2010

Detail Information

Publications383 found, 100 shown here

  1. ncbi Multivitamin-multimineral supplements: who uses them?
    Cheryl L Rock
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0901, USA
    Am J Clin Nutr 85:277S-279S. 2007
    Dietary supplement use is increasingly common in the United States. Multivitamin formulations with or without minerals are typically the most common type of dietary supplement reported in surveys and studies that collect data relating to ..
  2. ncbi A safe strategy for addition of vitamins and minerals to foods
    S E Rasmussen
    Danish Institute for Food and Veterinary Research, 19 Mørkhøj Bygade, 2860, Søborg, Denmark
    Eur J Nutr 45:123-35. 2006
    Addition of vitamins and minerals to foods must be done without health risk to any consumer group...
  3. ncbi Mineral metabolism, mortality, and morbidity in maintenance hemodialysis
    Geoffrey A Block
    Denver Nephrology Associates, Denver Colorado, USA
    J Am Soc Nephrol 15:2208-18. 2004
    ..Disorders of mineral metabolism are independently associated with mortality and morbidity associated with cardiovascular disease and fracture in hemodialysis patients...
  4. ncbi Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease
    Adrian Covic
    Dialysis and Renal Transplantation Center, C I Parhon University Hospital and University of Medicine Gr T Popa Iasi, Blvd Carol I Nr 50, Iasi, 700503, Romania
    Nephrol Dial Transplant 24:1506-23. 2009
    ..Thus, a systematic review was conducted to assess methodological and clinical heterogeneity by comparing designs, analytical approaches and results of studies...
  5. pmc Dietary supplement use is associated with higher intakes of minerals from food sources
    Regan L Bailey
    Office of Dietary Supplements, NIH, Bethesda, MD 20892 7517, USA
    Am J Clin Nutr 94:1376-81. 2011
    ..Some reports suggested that supplement users had higher nutrient intakes from the diet than did nonusers, but to our knowledge this finding has not been examined in nationally representative survey data...
  6. ncbi Progression of aortic calcification is associated with disorders of mineral metabolism and mortality in chronic dialysis patients
    Marlies Noordzij
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Nephrol Dial Transplant 26:1662-9. 2011
    ..In addition, we assessed the impact of aortic calcification on mortality...
  7. ncbi Metals, minerals and microbes: geomicrobiology and bioremediation
    Geoffrey Michael Gadd
    Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    Microbiology 156:609-43. 2010
    ..to geological phenomena, and central to many such geomicrobial processes are transformations of metals and minerals. Microbes have a variety of properties that can effect changes in metal speciation, toxicity and mobility, as ..
  8. pmc Materials become insensitive to flaws at nanoscale: lessons from nature
    Huajian Gao
    Max Planck Institute for Metals Research, Heisenbergstrasse 3, D 70569 Stuttgart, Germany
    Proc Natl Acad Sci U S A 100:5597-600. 2003
    Natural materials such as bone, tooth, and nacre are nanocomposites of proteins and minerals with superior strength...
  9. pmc Cooperative deformation of mineral and collagen in bone at the nanoscale
    Himadri S Gupta
    Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, D 144 24 Potsdam, Germany
    Proc Natl Acad Sci U S A 103:17741-6. 2006
    ..We believe this process results in a mechanism of fibril-matrix decoupling for protecting the brittle mineral phase in bone, while effectively redistributing the strain energy within the bone tissue...
  10. pmc Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males
    David O Kennedy
    Brain, Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK
    Psychopharmacology (Berl) 211:55-68. 2010
    A significant proportion of the general population report supplementing their diet with one or more vitamins or minerals, with common reasons for doing so being to combat stress and fatigue and to improve mental functioning...
  11. pmc Vitamin D, parathyroid hormone, and sudden cardiac death: results from the Cardiovascular Health Study
    Rajat Deo
    Section of Electrophysiology, Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hypertension 58:1021-8. 2011
    ..017) compared with participants with normal levels of PTH and 25-OHD. The combination of lower 25-OHD and higher PTH concentrations appears to be associated independently with SCD risk among older adults without cardiovascular disease...
  12. pmc Protein-mediated enamel mineralization
    Janet Moradian-Oldak
    Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA
    Front Biosci (Landmark Ed) 17:1996-2023. 2012
    ..The chapter will conclude by discussing the potential of enamel for regrowth...
  13. ncbi Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome
    Y Hataguchi
    Ako Kasei Co, Ltd, Ako City, Hyogo, Japan
    Eur J Clin Nutr 59:1093-6. 2005
    The effect of drinking deep-sea water on hair minerals was studied in patients with atopic eczema/dermatitis syndrome (AEDS)...
  14. ncbi Analyses of toxic metals and essential minerals in the hair of Arizona children with autism and associated conditions, and their mothers
    J B Adams
    Arizona State University, Tempe, AZ 85287 6006, USA
    Biol Trace Elem Res 110:193-209. 2006
    The objective of this study was to assess the levels of 39 toxic metals and essential minerals in hair samples of children with autism spectrum disorders and their mothers compared to controls...
  15. ncbi The effect of supplemental vitamins and minerals on the development of prostate cancer: a systematic review and meta-analysis
    Julie Stratton
    Primary Healthcare Research Unit, Agnes Cowan Hostel, St John s Newfoundland, A1B 3V6, Canada
    Fam Pract 28:243-52. 2011
    ..Vitamin supplementation is used for many purposes with mainly alleged benefits. One of these is the use of various vitamins for the prevention of prostate cancer...
  16. ncbi Amorphous Ca-phosphate precursors for Ca-carbonate biominerals mediated by Chromohalobacter marismortui
    Maria Angustias Rivadeneyra
    Department of Microbiology, Faculty of Pharmacy, University of Granada, Granada, Spain
    ISME J 4:922-32. 2010
    Although diverse microbial metabolisms are known to induce the precipitation of carbonate minerals, the mechanisms involved in the bacterial mediation, in particular nucleation, are still debated...
  17. ncbi Involvement of minerals in adherence of Legionella pneumophila to surfaces
    Mohamad Koubar
    Laboratoire Ecologie et Biologie des Interactions, UMR CNRS 7267, Equipe Microbiologie de l Eau, B36, Universite de Poitiers, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France
    Curr Microbiol 66:437-42. 2013
    ..Relationship between the presence of minerals in water and Legionella adherence to surfaces is not well-known...
  18. pmc Microbial interspecies electron transfer via electric currents through conductive minerals
    Souichiro Kato
    Hashimoto Light Energy Conversion Project, Exploratory Research for Advanced Technology ERATO, Japan Science and Technology Agency, Tokyo 113 8656, Japan
    Proc Natl Acad Sci U S A 109:10042-6. 2012
    ..Here, we show another possibility that IET also occurs via electric currents through natural conductive minerals. Our investigation revealed that electrically conductive magnetite nanoparticles facilitated IET from Geobacter ..
  19. ncbi Respiratory interactions of soil bacteria with (semi)conductive iron-oxide minerals
    Souichiro Kato
    Hashimoto Light Energy Conversion Project, ERATO, JST, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Environ Microbiol 12:3114-23. 2010
    ..Irrespective of the iron-oxide species (hematite, magnetite or ferrihydrite), the supplementation with iron-oxide minerals resulted in large increases (over 30-fold) in current, while only a moderate increase (∼10-fold) was observed ..
  20. ncbi Adherence to nutritional recommendations and subsequent cognitive performance: findings from the prospective Supplementation with Antioxidant Vitamins and Minerals 2 (SU.VI.MAX 2) study
    Emmanuelle Kesse-Guyot
    Unite de Recherche en Epidemiologie Nutritionnelle, U557 INSERM U1125 Inra Cnam Université Paris 13, CRNH IdF, Bobigny, France
    Am J Clin Nutr 93:200-10. 2011
    ..Few studies have investigated the long-term effect of overall nutritional recommendations on cognition...
  21. ncbi Aged keratinocyte phenotyping: morphology, biochemical markers and effects of Dead Sea minerals
    Yoram Soroka
    Myers Laboratory of Skin Biology and Biochemistry, Department of Biological Chemistry, The Hebrew University of Jerusalem at Givat Ram, Jerusalem 91904, Israel
    Exp Gerontol 43:947-57. 2008
    ..As a test case, we have measured the effects of Dead Sea minerals on keratinocyte cultures and human skin, and found that they stimulate proliferation and mitochondrial activity, ..
  22. pmc Vitamin and mineral supplement use by children and adolescents in the 1999-2004 National Health and Nutrition Examination Survey: relationship with nutrition, food security, physical activity, and health care access
    Ulfat Shaikh
    University of California Davis School of Medicine, 2516 Stockton Blvd, Sacramento, CA 95817, USA
    Arch Pediatr Adolesc Med 163:150-7. 2009
    ..To determine if vitamin and mineral supplement use among children and adolescents in the United States is associated with nutrition, food security, physical activity, and health care access...
  23. ncbi Magnesium hydroxide temporarily enhancing osteoblast activity and decreasing the osteoclast number in peri-implant bone remodelling
    C Janning
    Laboratory for Biomechanics and Biomaterials, Department of Orthopaedic Surgery, Hannover Medical School, Anna von Borries Strasse 1 7, 30625 Hannover, Germany
    Acta Biomater 6:1861-8. 2010
    ..Further studies have to evaluate if the enhanced bone growth is mainly due to the local magnesium ion concentration or the local alkalosis accompanying the Mg(OH)(2) dissolution...
  24. pmc Ionomics: studying the social network of mineral nutrients
    Ivan Baxter
    Bindley Bioscience Center, Purdue University, West Lafayette, IN, USA
    Curr Opin Plant Biol 12:381-6. 2009
    ..When combined with new genotyping technologies, ionomics provides a rapid way to identify genes that control elemental accumulation in plants...
  25. ncbi Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat x wild emmer wheat RIL population
    Zvi Peleg
    The Robert H Smith Institute of Plant Science and Genetics in Agriculture, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Theor Appl Genet 119:353-69. 2009
    ..Langdon) and wild emmer (accession G18-16). Wide genetic variation was found among the RILs for all grain minerals, with considerable transgressive effect. A total of 82 QTLs were mapped for 10 minerals with LOD score range of 3...
  26. ncbi The role of cellular micronutrient analysis, nutraceuticals, vitamins, antioxidants and minerals in the prevention and treatment of hypertension and cardiovascular disease
    Mark C Houston
    Hypertension Institute, 4230 Harding Road, Suite 400, Nashville, TN 37205, USA
    Ther Adv Cardiovasc Dis 4:165-83. 2010
    ..Optimal nutrition, nutraceuticals, vitamins, antioxidants, minerals, weight loss, exercise, smoking cessation and moderate restriction of alcohol and caffeine in addition to other ..
  27. ncbi Vitamins and minerals: a model for safe addition to foods
    Albert Flynn
    University College Cork, Department of Food and Nutritional Sciences, Cork, Ireland
    Eur J Nutr 42:118-30. 2003
    ..subgroups in most European populations have intakes below nationally recommended levels for several vitamins, minerals and trace elements, placing individuals at risk of suboptimal intake of important vitamins and minerals...
  28. ncbi Magnitude and impact of abnormal mineral metabolism in hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    Eric W Young
    University of Michigan Veterans Administration Medical Center, Ann Arbor, MI 48105, USA
    Am J Kidney Dis 44:34-8. 2004
    ..Mineral metabolism has emerged as an important predictor of morbidity and mortality in dialysis patients, independent of bone and muscle concerns. Several expert panels have issued management guidelines for mineral metabolism...
  29. ncbi Physiological functions of mineral micronutrients (Cu, Zn, Mn, Fe, Ni, Mo, B, Cl)
    Robert Hansch
    Institut fur Pflanzenbiologie, Technische Universitat Braunschweig, Braunschweig, Germany
    Curr Opin Plant Biol 12:259-66. 2009
    ..In this review, we focus on the major functions of mineral micronutrients, mostly in cases where they were shown as constituents of proteins, making a selection and highlighting some functions in more detail...
  30. ncbi Geomycology: biogeochemical transformations of rocks, minerals, metals and radionuclides by fungi, bioweathering and bioremediation
    Geoffrey M Gadd
    Division of Environmental and Applied Biology, College of Life Sciences, University of Dundee, Dundee DD1 4HN, UK
    Mycol Res 111:3-49. 2007
  31. ncbi Whole-plant mineral partitioning throughout the life cycle in Arabidopsis thaliana ecotypes Columbia, Landsberg erecta, Cape Verde Islands, and the mutant line ysl1ysl3
    Brian M Waters
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    New Phytol 177:389-405. 2008
    ..Shoot mineral content increased throughout the life cycle for all minerals, although tissue-specific mineral partitioning differed between genotypes...
  32. ncbi Dietary intake and serum and hair concentrations of minerals and their relationship with serum lipids and glucose levels in hypertensive and obese patients with insulin resistance
    Joanna Suliburska
    Department of Human Nutrition and Hygiene, Life Sciences University in Poznan, Wojska Polskiego 31, PL 60 624 Poznan, Poland
    Biol Trace Elem Res 139:137-50. 2011
    Inadequate minerals intake, as well as disruption of some metabolic processes in which microelements are cofactors, are suggested to lead to the development of hypertension...
  33. ncbi Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo
    R N D'Souza
    Department of Basic Sciences, Dental Branch, University of Texas Houston Health Science Center 77030, USA
    J Bone Miner Res 12:2040-9. 1997
    ..These data show that the developmental expression patterns of Dmp1 and DSPP are distinct, implying that these molecules serve different biological functions in vivo...
  34. pmc Serum alkaline phosphatase predicts mortality among maintenance hemodialysis patients
    Deborah L Regidor
    Harold Simmons Center for Kidney Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
    J Am Soc Nephrol 19:2193-203. 2008
    Several observational studies have demonstrated that serum levels of minerals and parathyroid hormone (PTH) have U- or J-shaped associations with mortality in maintenance hemodialysis patients, but the relationship between serum alkaline ..
  35. ncbi Genetic analysis identifies quantitative trait loci controlling rosette mineral concentrations in Arabidopsis thaliana under drought
    Artak Ghandilyan
    Laboratory of Genetics, Wageningen University, NL 6703 BD Wageningen, The Netherlands
    New Phytol 184:180-92. 2009
    ..The low number of common mineral concentration QTLs, shared among different RIL populations, tissues and conditions in Arabidopsis, suggests that breeding for robust, mineral biofortified crops will be complex...
  36. ncbi Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries
    Mahmoud Zureik
    National Institute of Health and Medical Research Unit 258, Villejuif, France
    Arterioscler Thromb Vasc Biol 24:1485-91. 2004
    ..Limited data exist from randomized trials evaluating, noninvasively, the impact of antioxidant supplementation on vascular structure and function...
  37. pmc Long-term use of supplemental vitamins and minerals does not reduce the risk of urothelial cell carcinoma of the bladder in the VITamins And Lifestyle study
    James M Hotaling
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98103, USA
    J Urol 185:1210-5. 2011
  38. pmc Mineral metabolism and inflammation in chronic kidney disease patients: a cross-sectional study
    Juan F Navarro-González
    Nephrology Service, University Hospital Nuestra Senora de Candelaria, Spain
    Clin J Am Soc Nephrol 4:1646-54. 2009
    ..Mineral metabolism abnormalities and inflammation are concerns in chronic kidney disease (CKD). Interrelationships among these parameters have not been analyzed...
  39. ncbi Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations
    F Inchingolo
    School in Dental Hygiene, Faculty of Medicine, University Aldo Moro, Bari, Italy
    Eur Rev Med Pharmacol Sci 14:1075-84. 2010
  40. ncbi Criticality of non-fuel minerals: a review of major approaches and analyses
    Lorenz Erdmann
    Institute for Futures Studies and Technology Assessment IZT, Schopenhauerstrasse 26, 14129 Berlin, Germany
    Environ Sci Technol 45:7620-30. 2011
    The criticality of nonfuel minerals is an emerging research subject that captures both the supply risks and the vulnerability of a system to a potential supply disruption...
  41. ncbi Biodiversity, metabolism and applications of acidophilic sulfur-metabolizing microorganisms
    Mark Dopson
    School of Natural Sciences, Linnaeus University, Kalmar, Sweden
    Environ Microbiol 14:2620-31. 2012
    ..Finally, existing and developing technologies that harness the abilities of sulfur-oxidizing and sulfate-reducing acidophiles to extract and capture metals, and to remediate sulfur-polluted waste waters are outlined...
  42. ncbi Dietary intake of six minerals in relation to the risk of chronic obstructive pulmonary disease
    Fumi Hirayama
    Department of Global Health Policy, Graduate School of Medi cine, University of Tokyo, Bankyo ku, Tokyo, 113 0033, Japan
    Asia Pac J Clin Nutr 19:572-7. 2010
    To investigate the relationship between dietary intake of minerals and the risk of chronic obstructive pulmonary disease (COPD), a case-control study was conducted in central Japan...
  43. ncbi Arsenic transformation and mobilization from minerals by the arsenite oxidizing strain WAO
    E Danielle Rhine
    Biotechnology Center for Agriculture and the Environment and Department of Environmental Sciences, Cook College, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA
    Environ Sci Technol 42:1423-9. 2008
  44. pmc Quantitative trait loci affecting seed mineral concentrations in Brassica napus grown with contrasting phosphorus supplies
    Guangda Ding
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China
    Ann Bot 105:1221-34. 2010
    ..The aims of this study were to identify and characterize genetic loci (QTLs) controlling the accumulation of mineral elements in seeds of Brassica napus grown with contrasting P availabilities...
  45. pmc Transpiration, a prerequisite for long-distance transport of minerals in plants?
    W Tanner
    Institute of Cell Biology and Plant Physiology, University of Regensburg, 93040 Regensburg, Germany
    Proc Natl Acad Sci U S A 98:9443-7. 2001
  46. ncbi Influence of minerals on lead-induced alterations in liver function in rats exposed to long-term lead exposure
    D souza Sunil Herman
    Department of Biotechnology, Manipal Life Sciences Centre, KMC, Manipal University, Manipal, India
    J Hazard Mater 166:1410-4. 2009
    The objective of this study was to evaluate the role of minerals on lead-induced effect on the liver. Differentiation of minerals and heavy metals pose an inherent problem due to certain common properties shared by them...
  47. ncbi A review of select vitamins and minerals used by postmenopausal women
    Cathi Dennehy
    Department of Clinical Pharmacy, UCSF School of Pharmacy, San Francisco, CA 94143, USA
    Maturitas 66:370-80. 2010
    The purpose of this review is to summarize the effectiveness of select vitamins, minerals and trace elements in postmenopausal women for their effects on bone health, cardiovascular health, breast cancer, cognition and vasomotor symptoms.
  48. ncbi Organic acid-induced release of lead from pyromorphite and its relevance to reclamation of Pb-contaminated soils
    F Debela
    University of Northern British Columbia, Prince George, BC Canada V2N4Z9
    Chemosphere 80:450-6. 2010
    ..This suggests that soil organic acids such as in rhizosphere can potentially liberate Pb from PY in contaminated soils...
  49. pmc Minerals form a continuum phase in mature cancellous bone
    Po Yu Chen
    Materials Science and Engineering Program, Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0411, USA
    Calcif Tissue Int 88:351-61. 2011
    ..SEM revealed that bone minerals are fused together and form a sheet-like structure in a coherent manner with collagen fibrils...
  50. pmc The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue
    Delphine Farlay
    INSERM, UMR 1033, Lyon, France
    PLoS ONE 6:e28736. 2011
  51. pmc Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase
    Mutsuko Ohnishi
    Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA
    Kidney Int 75:1166-72. 2009
    ..These in vivo studies suggest that vitamin D has a pathologic role in regulating abnormal mineral ion metabolism and soft-tissue anomalies of klotho-deficient mice...
  52. ncbi The Kidney Disease: improving Global Outcomes website: comparison of guidelines as a tool for harmonization
    H Vanbelleghem
    University Hospital, Gent, Belgium
    Kidney Int 71:1054-61. 2007
    ..The tables displayed on the website offer a basis for structuring this process, a procedure which has recently been initiated by a body composed of the five guideline development groups...
  53. ncbi Dental caries in diabetes mellitus: role of salivary flow rate and minerals
    Muhammad Jawed
    Department of Biochemistry, Liaquat College of Medicine and Dentistry, Karachi, Pakistan
    J Diabetes Complications 25:183-6. 2011
    ..Adequate level of salivary calcium, phosphate, and fluoride is also involved in significant deposition of these minerals in plaque, which greatly reduces the development of caries in the adjacent enamel of teeth.
  54. ncbi Disordered mineral metabolism in hemodialysis patients: an analysis of cumulative effects in the Hemodialysis (HEMO) Study
    Ron Wald
    Division of Nephrology and The Keenan Research Centre in the Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada
    Am J Kidney Dis 52:531-40. 2008
    ..Although the values of these markers often evolve over time, no study has examined the accumulated effects of these abnormalities on important clinical end points...
  55. pmc Dynamic changes in the distribution of minerals in relation to phytic acid accumulation during rice seed development
    Toru Iwai
    Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo ku, Tokyo 113 8657, Japan
    Plant Physiol 160:2007-14. 2012
    ..Copper accumulated in the endosperm and may exhibit a storage form other than phytate...
  56. ncbi Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain
    J Vormann
    Institut für Prävention und Ernährung, Ismaning, Germany
    J Trace Elem Med Biol 15:179-83. 2001
    ..It was tested whether a supplementation with alkaline minerals would influence symptoms in patients with low back pain symptoms...
  57. ncbi Comparative evaluation of the dustiness of industrial minerals according to European standard EN 15051, 2006
    Ingeborg Pensis
    Ankerpoort NV, Op de Bos 300, NL 6223 EP Maastricht, The Netherlands
    Ann Occup Hyg 54:204-16. 2010
    A range of industrial minerals was tested using the rotating drum and the continuous drop methods, the two methods proposed by the published European standard EN 15051 [CEN...
  58. pmc Congestive heart failure: where homeostasis begets dyshomeostasis
    German Kamalov
    Division of Cardiovascular Diseases, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Cardiovasc Pharmacol 56:320-8. 2010
  59. ncbi Associations of serum minerals with body mass index in adult women
    C H Song
    Department of Family Medicine, St Mary s Hospital, School of Medicine, The Catholic University of Korea, Seoul, Korea
    Eur J Clin Nutr 61:682-5. 2007
    This cross-sectional study evaluated the association between serum minerals and body mass index in adult women.
  60. ncbi Ultrastructure and mineral distribution in the tergal cuticle of the terrestrial isopod Titanethes albus. Adaptations to a karst cave biotope
    Sabine Hild
    Central Facility for Electron Microscopy, University of Ulm, Ulm, Germany
    J Struct Biol 168:426-36. 2009
    ..This may possibly be of advantage in maintaining high cuticle flexibility and reducing metabolic expenditures...
  61. ncbi Age-dependent changes in matrix composition and organization at the ligament-to-bone insertion
    I Ning E Wang
    Biomaterials and Interface Tissue Engineering Laboratory, Department of Biomedical Engineering, Columbia University, 1210 Amsterdam Ave, 351 Engineering Terrace Bldg, MC8904, New York, New York 10027, USA
    J Orthop Res 24:1745-55. 2006
    ..cartilage oligomeric matrix protein (COMP), glycosaminoglycan (GAG), alkaline phosphatase (ALP) activity, and minerals at the ACL-to-bone insertion were examined...
  62. ncbi Nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertension
    Mark C Houston
    Department of Medicine, Division of General Internal Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Prog Cardiovasc Dis 47:396-449. 2005
    ..Optimal nutrition, nutraceuticals, vitamins, antioxidants, minerals, weight loss, exercise, smoking cessation, and moderate restriction of alcohol and caffeine in addition to other ..
  63. pmc In vitro mineralization of dense collagen substrates: a biomimetic approach toward the development of bone-graft materials
    Taili T Thula
    Materials Science and Engineering Department, University of Florida, Gainesville, FL 32611 6400, USA
    Acta Biomater 7:3158-69. 2011
    ..These studies demonstrate that the original interpenetrating bone nanostructure and osteonal microstructure could be recovered in a biogenic matrix using the PILP process...
  64. ncbi Respective roles of organic and mineral components of human cortical bone matrix in micromechanical behavior: an instrumented indentation study
    Y Bala
    INSERM, UMR1033, F 69008 Lyon, France
    J Mech Behav Biomed Mater 4:1473-82. 2011
    ..Contact hardness, reflecting both elastic and plastic behaviors, was correlated with both DMB and collagen maturity. No relationship was found between crystallinity and mechanical properties at the osteon level...
  65. ncbi Use of vitamin, mineral, nonvitamin, and nonmineral supplements in the United States: The 1987, 1992, and 2000 National Health Interview Survey results
    Amy E Millen
    National Cancer Institute, Division of Cancer and Population Sciences, Bethesda, MD 20892 7344, USA
    J Am Diet Assoc 104:942-50. 2004
    ..To describe trends in use of specific vitamin and mineral (VM) supplements...
  66. pmc Mineralisation of reconstituted collagen using polyvinylphosphonic acid/polyacrylic acid templating matrix protein analogues in the presence of calcium, phosphate and hydroxyl ions
    Young Kyung Kim
    Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu 700 412, Republic of Korea
    Biomaterials 31:6618-27. 2010
    ..Selected area electron diffraction patterns of highly mineralised collagen fibrils were nearly identical to those of natural bone, with apatite crystallites preferentially aligned along the collagen fibril axes...
  67. ncbi A strong effect of growth medium and organ type on the identification of QTLs for phytate and mineral concentrations in three Arabidopsis thaliana RIL populations
    Artak Ghandilyan
    Wageningen University, Arboretumlaan, The Netherlands
    J Exp Bot 60:1409-25. 2009
    ..with several genetic loci involved in the control of one mineral and loci affecting the accumulation of different minerals. To investigate the role of growth medium and organ type on the genetics of mineral accumulation, two existing (..
  68. pmc Effect of a supplement rich in alkaline minerals on acid-base balance in humans
    Daniel König
    University Hospital Freiburg, Centre for Internal Medicine, Department of Rehabilitation, Prevention and Sports Medicine, Germany
    Nutr J 8:23. 2009
    Western diets are considered acidogenic due to the high dietary acid load and a low intake of base-forming dietary minerals such as potassium, magnesium or calcium...
  69. ncbi Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomes
    Lesley A Stevens
    Division of Nephrology, New England Medical Centre, Boston, Massachusetts, USA
    J Am Soc Nephrol 15:770-9. 2004
    ..In so doing, the complex interaction of time and MM can begin to be understand. Further exploration is required...
  70. ncbi Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guaraná (Paullinia cupana)
    D O Kennedy
    Human Cognitive Neuroscience Unit, Northumbria University, Newcastle upon Tyne NE1 8ST, UK
    Appetite 50:506-13. 2008
  71. ncbi Traditional and nontraditional supplement use by collegiate female varsity athletes
    Nancie H Herbold
    Dept of Nutrition at Simmons College, Boston, MA 02115, USA
    Int J Sport Nutr Exerc Metab 14:586-93. 2004
    ..1%). A major source of information on supplements reported was family (53%). With the general rise in supplement use, nutrition education on the use of traditional and non-traditional supplements is warranted...
  72. ncbi Association of mineral metabolism factors with all-cause and cardiovascular mortality in hemodialysis patients: the Japan dialysis outcomes and practice patterns study
    Naoki Kimata
    Kidney Center, Division of Blood Purification, Tokyo Women s Medical University, Tokyo, Japan
    Hemodial Int 11:340-8. 2007
    ..These findings have important therapeutic implications for Japanese HD patients...
  73. ncbi Dietary minerals and modification of cardiovascular risk factors
    Timo Vaskonen
    Institute of Biomedicine, University of Helsinki, Helsinki, Finland
    J Nutr Biochem 14:492-506. 2003
    ..This review summarizes previous literature on the effects and use of dietary minerals on serum lipids, blood pressure and obesity, with specific focus on the effects of calcium...
  74. ncbi Synchrotron diffraction study of deformation mechanisms in mineralized tendon
    H S Gupta
    Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, 14424 Potsdam, Germany
    Phys Rev Lett 93:158101. 2004
    ..Scanning electron microscopy measurements lead us to conclude that the inhomogeneous mineralization in mineralized tendon is at the origin of the high fracture strain...
  75. ncbi Other relevant components of nuts: phytosterols, folate and minerals
    Ramon Segura
    Department of Physiological Sciences II, Faculty of Medicine, IDIBELL, University of Barcelona, Barcelona, Spain
    Br J Nutr 96:S36-44. 2006
    ..Compared to other common foodstuffs, nuts have an optimal nutritional density with respect to healthy minerals, such as calcium, magnesium and potassium. Like that of most vegetables, the sodium content of nuts is very low...
  76. ncbi Life in blue: copper resistance mechanisms of bacteria and archaea used in industrial biomining of minerals
    Alvaro Orell
    Laboratory of Molecular Microbiology and Biotechnology, Department of Biology, and Millennium Institute for Cell Dynamics and Biotechnology, Faculty of Sciences, University of Chile, Santiago, Chile
    Biotechnol Adv 28:839-48. 2010
    ..In turn, this information could be used to select the more fit members of the bioleaching community to attain more efficient industrial biomining processes...
  77. ncbi Characteristics of mineral particles in the human bone/cartilage interface
    I Zizak
    Erich Schmid Institute of Materials Science and Metal Physics Institute, Austrian Academy of Sciences and University of Leoben, Jahnstr 12, A 8700, Leoben, Austria
    J Struct Biol 141:208-17. 2003
    ..The tight bonding of mineralized cartilage to bone suggests a mechanical role for the interface of the two elastically different tissues, bone and cartilage...
  78. ncbi Moving cationic minerals to edible tissues: potassium, magnesium, calcium
    Alison J Karley
    Scottish Crop Research Institute, Dundee, UK
    Curr Opin Plant Biol 12:291-8. 2009
    ..The techniques of ionomics can help identify better genotypes...
  79. pmc A gastrolith protein serving a dual role in the formation of an amorphous mineral containing extracellular matrix
    Assaf Shechter
    Department of Life Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Proc Natl Acad Sci U S A 105:7129-34. 2008
    ..Thus, GAP 65 is the first protein shown to have dual function, involved both in extracellular matrix formation and in mineral deposition during biomineralization...
  80. pmc The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification
    Cora Schafer
    Interdisciplinary Center for Clinical Research on Biochematerials, University Clinics, Aachen, Germany
    J Clin Invest 112:357-66. 2003
    ..Taken together, our data demonstrate a critical role of Ahsg as an inhibitor of unwanted mineralization and provide a novel therapeutic concept to prevent ectopic calcification accompanying various diseases...
  81. ncbi Minerals, trace elements and related biological variables in athletes and during physical activity
    M Speich
    Département de Santé Publique et de Pharmacie Clinique, Faculte de Pharmacie, Universite de Nantes, L, rue Gaston Veil, B P 53508, F 44035 Cedex 1, Nantes, France
    Clin Chim Acta 312:1-11. 2001
    This review concerns various minerals (sodium, potassium, calcium, magnesium, phosphorus), trace elements (zinc, manganese, selenium, copper, iron, cobalt, iodine, chromium, fluorine, lead, cadmium) and other biological variables (nitric ..
  82. ncbi Identification of QTL affecting seed mineral concentrations and content in the model legume Medicago truncatula
    Renuka P Sankaran
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Theor Appl Genet 119:241-53. 2009
    ..seeds have the potential to provide the essential nutrients required by humans, but concentrations of several minerals are low when compared to other foods...
  83. ncbi Healing around implants placed in bone defects treated with Bio-Oss. An experimental study in the dog
    T Berglundh
    Department of Periodontology, Goteborg University, Sweden
    Clin Oral Implants Res 8:117-24. 1997
    ..It was also observed that 4 months after implant installation, the titanium/hard tissue interface at test and control sites exhibited, from both a quantitative and qualitative aspect, a similar degree of "osseointegration"...
  84. ncbi Increasing the sink:source balance enhances photosynthetic rate of 1-year-old balsam fir foliage by increasing allocation of mineral nutrients
    M B Lavigne
    Natural Resources Canada, Canadian Forest Service, Atlantic Forestry Centre, P.O. Box 4000, Fredericton, NB E3C 5P7, Canada
    Tree Physiol 21:417-26. 2001
  85. ncbi Orientation of mineral crystallites and mineral density during skeletal development in mice deficient in tissue nonspecific alkaline phosphatase
    W Tesch
    Ludwig Boltzmann Institute of Osteology 4th Medical Department, Hanusch Hospital and UKH Meidling, Vienna, Austria
    J Bone Miner Res 18:117-25. 2003
  86. ncbi The distribution of minerals and flavonoids in the tea plant (Camellia sinensis)
    L Ferrara
    Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy Federico II University, Naples, Italy
    Farmaco 56:397-401. 2001
    ..Tea contains volatile oils, vitamins, minerals, purines, polyphenols, particularly carechins...
  87. ncbi Mineral metabolism parameters throughout chronic kidney disease stages 1-5--achievement of K/DOQI target ranges
    Lourdes Craver
    Hospital Universitari Arnau de Vilanova, Av Rovira Roure, 25198 Lleida, Spain
    Nephrol Dial Transplant 22:1171-6. 2007
    ..The objective of this study is to provide an in-depth description of mineral metabolism in the early stages of CKD in a European population, and to compare it with current recommendations for stages 3-5 (K/DOQI guidelines)...
  88. ncbi Clinical outcomes following treatment of human intrabony defects with GTR/bone replacement material or access flap alone. A multicenter randomized controlled clinical trial
    Maurizio S Tonetti
    Department of Periodontology, Eastman Dental Institute, University College London, London, UK
    J Clin Periodontol 31:770-6. 2004
  89. ncbi Aspects of mineral structure in normally calcifying avian tendon
    L M Siperko
    Department of Biochemistry and Molecular Pathology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272, USA
    J Struct Biol 135:313-20. 2001
  90. ncbi Evolutionary control of leaf element composition in plants
    Toshihiro Watanabe
    Research Faculty of Agriculture, Hokkaido University, N9W9, Kita ku, Sapporo 060 8589, Japan
    New Phytol 174:516-23. 2007
    ..Identifying mechanisms by which different plant families control their leaf elemental concentration remains a challenge...
  91. ncbi Size and shape of mineralites in young bovine bone measured by atomic force microscopy
    W Tong
    Nanoscale Orthopedic Biomaterials Laboratory, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106 7207, USA
    Calcif Tissue Int 72:592-8. 2003
  92. ncbi Comparative contents of dietary fiber, total phenolics, and minerals in persimmons and apples
    S Gorinstein
    Department of Medicinal Chemistry, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
    J Agric Food Chem 49:952-7. 2001
    Dietary fibers, major phenolics, main minerals, and trace elements in persimmons and apples were analyzed and compared in order to choose a preferable fruit for an antiatherosclerotic diet...
  93. ncbi Antioxidant supplementation does not affect fasting plasma glucose in the Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations
    Sebastien Czernichow
    Nutritional Epidemiology Unit, French Institute of Health and Medical Research, CRNH Ile de France, Bobigny, France
    Am J Clin Nutr 84:395-9. 2006
    ..Observational data suggest a protective effect of several antioxidants on fasting plasma glucose (FPG) and type 2 diabetes. However, randomized trials have yielded inconsistent results...
  94. ncbi The role of a homoeopathic preparation compared with conventional therapy in the treatment of injuries: an observational cohort study
    Christian Schneider
    Klinik für Ganzheitsmedizin, Herrsching, Germany
    Complement Ther Med 16:22-7. 2008
    ..To assess the use, effectiveness and safety of a homoeopathic preparation (Traumeel) compared with conventional therapies in the treatment of trauma and injuries...
  95. ncbi Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients
    Ewelina Krol
    Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, 31 Wojska Polskiego, 60 624, Poznan, Poland
    Biol Trace Elem Res 143:726-37. 2011
    ..8%) in type 2 diabetic patients. In conclusion, Cr brewer's yeast has a weak hypoglycemic potential, but does not affect body mass, blood biochemical profile, and microelement levels in type 2 diabetic subjects...
  96. ncbi Dietary intake of seaweed and minerals and prevalence of allergic rhinitis in Japanese pregnant females: baseline data from the Osaka Maternal and Child Health Study
    Yoshihiro Miyake
    Department of Public Health, Fukuoka University School of Medicine, Japan
    Ann Epidemiol 16:614-21. 2006
    ..This cross-sectional study investigated the relationship between dietary intake of seaweed, vegetables, fruit, antioxidants, fiber, and minerals and the prevalence of allergic rhinitis.
  97. ncbi Critical evaluation of strategies for mineral fortification of staple food crops
    Sonia Gomez-Galera
    Department of Vegetal Production and Forestry Science, ETSEA, University of Lleida, 25198 Lleida, Spain
    Transgenic Res 19:165-80. 2010
  98. ncbi Vitamins, minerals, and mood
    Bonnie J Kaplan
    Department of Pediatrics, University of Calgary, Calgary, AB, Canada
    Psychol Bull 133:747-60. 2007
    In this article, the authors explore the breadth and depth of published research linking dietary vitamins and minerals (micronutrients) to mood...
  99. ncbi Biofortification of crops with seven mineral elements often lacking in human diets--iron, zinc, copper, calcium, magnesium, selenium and iodine
    Philip J White
    The Scottish Crop Research Institute, Invergowrie, Dundee, UK
    New Phytol 182:49-84. 2009
    ..These approaches are addressing mineral malnutrition in humans globally...
  100. pmc Minerals and vitamins and the risk of bladder cancer: results from the New Hampshire Study
    Maree T Brinkman
    Cancer Epidemiology Centre, The Cancer Council Victoria, 1 Rathdowne Street, Carlton, VIC 3053, Australia
    Cancer Causes Control 21:609-19. 2010
    ..Our aim was to investigate associations between minerals and vitamins and bladder cancer.
  101. ncbi Comparison of the nutritional profile of glyphosate-tolerant corn event NK603 with that of conventional corn (Zea mays L.)
    William P Ridley
    Product Safety Center, Monsanto Company, 800 North Lindbergh Boulevard, St Louis, Missouri 63167, USA
    J Agric Food Chem 50:7235-43. 2002
    ..and compositional analyses were performed to measure proximates, fiber, amino acids, fatty acids, vitamin E, nine minerals, phytic acid, trypsin inhibitor, and secondary metabolites in grain as well as proximates and fiber in forage...

Research Grants64

  1. Enhanced iron removal with peptide linked chelators targeted to ferritin
    Elizabeth C Theil; Fiscal Year: 2010
    ..Ferritin is a protein nanocage that synthesizes ferric oxide minerals from Fe (II) substrate, inside the cage...
  2. Impact of Microparticles on Oral TSE Infections
    Joel A Pedersen; Fiscal Year: 2012
    ..We have recently demonstrated that prions bind to soil, clay minerals and silicon dioxide (Johnson et al., 2007)...
  3. New drug VS-501 for treating hyperphosphatemia in chronic kidney disease
    Jinshyun Ruth Wu-Wong; Fiscal Year: 2012
    ..derived from plants that is chemically processed to become highly effective in absorbing phosphate and other minerals in the GI tract without systemic toxicology effects...
  4. Studies of Lymphoma Suppression and DNA Repair
    Chunying Du; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Ionizing radiation (IR), produced by certain minerals in the Earth, represents a major environmental health hazard to man because it causes DNA double-strand breaks (DSBs), highly toxic DNA lesions ..
  5. The Role of Cytokine Signaling in Arsenic Induced Insulin Resistance
    INGRID DRUWE; Fiscal Year: 2010
    ..the ground water of Western, Midwestern and Northeastern areas of the United States, largely as a result of minerals dissolving from weathered rocks and soils...
    David A Bushinsky; Fiscal Year: 2010
    ..Bone neutralizes the acid but, in doing so, loses calcium and other minerals. The current proposal is aimed at understanding the first steps by which acid is detected by bone cells...
  7. Genetic controls of mineral consumption
    Michael G Tordoff; Fiscal Year: 2013
    ..We have already identified several quantitative trait loci (QTLs) related to consumption of these minerals. We propose here to identify the genes underlying some of these QTLs...
  8. Enhancing Dietary Iron and Zinc Bioavailability in Indian Children
    Steven A Abrams; Fiscal Year: 2010
    ..Improving the intake of bioavailable minerals would be crucial to enhancing the health of the Indian population as it will improve school and work performance ..
  9. The Role of HMGB1 in the Pathogenesis of Mesothelioma
    Haining Yang; Fiscal Year: 2013
    ..plays a role and in some high-risk MM families in the US and in Cappadocia, Turkey that were exposed to these minerals, over 50% of family members have died of MM...
  10. Impact of chronic caloric restriction on resident progenitor cells in the heart
    KURT SAUPE; Fiscal Year: 2009
    ..and lifespan extended by placing animals on a diet that is very low in calories and enriched in vitamins and minerals. How this type of diet slows aging and prevents age-associated diseases is not known...
  11. Dietary Marine Algae Extract and Colon Cancer Chemoprevention
    James Varani; Fiscal Year: 2010
    ..The extract is rich in Ca2+ but also contains detectable levels of approximately 70 other minerals. Two pivitol questions will be addressed in this study...
  12. The effects of engineered nanoparticle ingestion on mineral absorption and small
    Gretchen Mahler; Fiscal Year: 2013
    ..We will determine whether nanoparticles can interfere with the absorption of iron and zinc, two essential minerals. We will establish whether nanoparticle exposure alters gene or protein expression of mineral and nutrient ..
  13. The Libby Community Childhood Health Investigation and Exposure Follow-Up Study (
    Grace LeMasters; Fiscal Year: 2012
    ..The Libby vermiculite, referred to as Libby Amphibole (LA), contains asbestos minerals and exposure is associated with pulmonary function loss, pleural and interstitial lung diseases and respiratory ..
  14. Interactions Between Oral Biofilms and Dental Resin Composites
    Joel D Rudney; Fiscal Year: 2013
    ..Both OCT and micro-CT imaging will be used to monitor the loss of minerals in the tooth tissues, while microhardness testing and Fourier-transform infrared spectrometry will be performed ..
  15. Medical Food Cocktail for Alzheimer's Disease
    CURT H HENDRIX; Fiscal Year: 2010
    ..Akeso Health Sciences (Akeso) medical food cocktail is composed of standardized herbal extracts, vitamins, and minerals that are demonstrated in the basic science and clinical medical literature to impact the biochemical and ..
  16. Biomimetic Nanomatrix for Bone Tissue Regeneration
    Joel M Anderson; Fiscal Year: 2011
    ..The bone ECM consists of organic fibrous proteins and reinforcing inorganic phosphate minerals primarily composed of hydroxyapatite (HA)...
  17. Analysis of arsenic in inducing ROS, signaling pathways, and lung carcinogenesis
    Bing Hua Jiang; Fiscal Year: 2010
    Arsenic is widely spread in the environment such as soil, minerals, smoke, contaminated air and water. Epidemiologic studies showed that inorganic arsenic exposure induced lung, skin, liver, and bladder cancers...
  18. Cancer Prevention/Risk Assessments from DNA Modification Levels
    Nathalie Zeitouni; Fiscal Year: 2010
    ..in which non-melanoma dermatology patients/healthy volunteer will take the same combination of antioxidants and minerals for 8 weeks that has been shown to reduce cancer in men by 31%...
  19. Antibacterial activities of natural minerals and alternative treatment for infect
    Shelley E Haydel; Fiscal Year: 2013
    ..nanominerals to heal skin infections has been evident since the earliest recorded history, and specific clay minerals may prove valuable in the treatment of bacterial diseases, including infections for which there are no effective ..
  20. Structural determinants of amelogenin function in regulating enamel formation
    Henry C Margolis; Fiscal Year: 2013
    ..the transformation of aligned ACP particles to ordered bundles of HA crystals, by testing the hypothesis that disordered ACP-like minerals will persist in vivo, in the absence of enamelysin, in contrast to what is seen in wild type mice.
  21. Libby Epidemiology Research Program
    Raja M Flores; Fiscal Year: 2013
    Description (Provided by Applicant): Residents of Libby, MT, have been exposed to asbestiform minerals (Libby amphibole, or LA) including tremolite and other regulated amphibole types as well as unregulated fibers including winchite and ..
  22. Nano-scale Mechanisms of Metal(loid) Rhizostabilization in Desert Mine Tailings
    JONATHAN D CHOROVER; Fiscal Year: 2011
    ..experiment using an array of advanced tools that can interrogate the complex associations of roots, microbes, minerals and metals at high spatial resolution...
  23. Spirit Lake Sioux Nation Diabetes Education Project
    CYNTHIA LINDQUIST MALA; Fiscal Year: 2009
    ..The chemistry of foods including natural foods, processed foods, vitamins, minerals, and the social customs of food use and distribution will be developed...
  24. The influence of pricing and nutrient profiling on food purchases
    Leonard H Epstein; Fiscal Year: 2013
    ..that scores foods on a 1-100 scale based on an algorithm that takes in to account positive (fiber, vitamins, minerals, Omega 3 fatty acids, etc...
  25. Biomimetic remineralization of resin-dentin bonds
    FRANKLIN CHI MENG TAY; Fiscal Year: 2010
    ..and nanotechnology concepts for remineralizing denuded collagen matrices within hybrid layers and depositing minerals to form nanocomposites within porous adhesive layers should be investigated as a more assertive means to improve ..
  26. Evaluation of a low-fluoride anticaries toothpaste containing an innovative calci
    Robert L Karlinsey; Fiscal Year: 2010
    ..ppm F) relative to existing OTC fluoride toothpastes may be possible if other fluoride-compatible tooth-building minerals could be included in the formulation...
  27. Pilot-scale Research of Novel Amendment Delivery for in-situ Sediment Remediation
    Upal Ghosh; Fiscal Year: 2009
    ..by adding sorbent amendments such as activated carbon for binding persistent organic pollutants and natural minerals such as apatite, zeolites, or bauxite for the binding of toxic metals in sediments...
  28. The Genetic Basis of Natural Ionomic Variation
    Mary Lou Guerinot; Fiscal Year: 2013
    ..Fe, Zn, Mn, Co, Ni, Se, Mo, I (micronutrients of significance to plant and human health);Na, As, and Cd (minerals causing agricultural or environmental problems)...
  29. An anti-inflammatory role for bioactive nutrient isothiocyanates
    Janet V Cross; Fiscal Year: 2010
    Fresh fruits and vegetables are the foundation of a healthy diet. They not only provide vitamins and minerals that are essential for human health, but they also contain bioactive nutrients that have demonstrated efficacy in preventing ..
    Theodore Kurtz; Fiscal Year: 1990
    ..The changes in body weight, extracellular fluid volume, plasma volume, external balances of minerals and electrolytes, and plasma concentrations of renin, aldosterone, catecholamines, parathyroid hormone and ..
  31. Dietary Factors Affecting Calcium and Zinc Absorption
    Steven Abrams; Fiscal Year: 2006
    ..Although calcium is the most important bone mineral, it is well recognized that other minerals, including zinc, are crucial for growth and bone mineralization...
    JOHN FORDTRAN; Fiscal Year: 2002
    ..includes metabolic balance methods to measure net gastrointestinal absorption or secretin of nutrients, minerals and electrolytes; or steady state intestinal perfusion which allows detailed examination of mucosal absorption or ..
  33. Influence of Dietary Flavonoids on the Expression of At*
    Carl Keen; Fiscal Year: 2002
    ..Vitamins and minerals contribute to the oxidative defense system because: (1) they are antioxidants (vitamins E, C and B-carotene); (2) ..
    Cutberto Garza; Fiscal Year: 1991
    ..or on the occurrence of morbidity and mortality; milk quality on the concentrations of proteins, fats, and minerals; and that of milk quantity on production volumes and concentrations...
  35. Assess structure and microbial interactions of clay mineral antibacterial agent
    Lynda Williams; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Certain clay minerals have been shown to inhibit growth of some bacterial pathogens...
  36. Repiratory Health and Community Asbestos Exposure
    Bruce Alexander; Fiscal Year: 2007
    ..asbestos exposure from processing asbestos contaminated vermiculite ore from Libby Montana at the Western Minerals/WR Grace facility...
  37. Regulation of minerals and fluids excretion in vitamin D
    Yan Chun Li; Fiscal Year: 2005
    ..The third goal is to study the effect of VDR inactivation on ANP expression and sodium and body fluid balance, in order to test in vivo, the hypothesis that 1,25(OH)2D3 negatively regulates ANP expression. ..
    RICHARD SCHANLER; Fiscal Year: 2000
    Although the use of fortified mother's milk (FMM, mother's own milk plus supplemental protein, minerals, and vitamins) for feeding premature infants is increasing, it is a difficult process for the mothers and may become costly...
    Robert Knopp; Fiscal Year: 2002
    ..homocysteine levels, other antioxidants such as isoflavones and carotenoids, plant estrogens, soya, salt, trace minerals and alcohol...
  40. Electrolytic Control of Biofilm in Dental Units & Water
    Anne Camper; Fiscal Year: 2004
    ..It will generate oxygen and hydrogen in solution and other active oxidants from the minerals naturally present in the municipal water supply. It will not require a periodic flush...
    David Ledbetter; Fiscal Year: 2001
    ..b>Minerals play key roles in numerous biological reactions within the body and adequate intakes are essential to maintain ..
  42. The Lung: A Reaction Chamber for Asbestiform Minerals
    Scott Wood; Fiscal Year: 2002
    ..Moreover, conversions of minerals occur in many low-temperature environments (e.g...
    FLORIAN CERKLEWSKI; Fiscal Year: 1991
    ..In this case, we would have the opportunity to determine if the relationship found influenced caries (dental decay) resistance of offspring molar teeth...
  44. Grape Seed Extract-Cardiac Impact and Drug Interaction
    Steven Bolling; Fiscal Year: 2005
    ..As such, many patients of conventional health care are consuming antioxidant supplements from vitamins, minerals, and botanicals...
  45. Spirit Lake Sioux Nation Diabetes Education Project
    EFTHALIA ESSER; Fiscal Year: 2004
    ..The chemistry of foods including natural foods, processed foods, vitamins, minerals, and the social customs of food use and distribution will be developed...
  46. Nanostructured Block-copolymer Reinforced Calcium Phosphate Composites
    LARA ESTROFF; Fiscal Year: 2009
    ..Our approach is to combine calcium phosphate minerals with the well-established ability of amphiphilic (hydrophobic/hydrophilic) block copolymers to direct the ..
    DOSUK LEE; Fiscal Year: 1990
    ..stereomicroscopy together with computer graphic reconstructions to obtain threedimensional locations of the minerals in respect to the tissue ultrastructure...
    JACK METCOFF; Fiscal Year: 1980
    ..1) whether altered modulation of regulatory enzymes by imbalances of normal nutrients, metabolites and trace minerals produce changes in CHO, fat and protein metabolism which characterize uremia; (2) whether limitations in one ..
  49. Cadmium Exposure and Breast Cancer Risk
    Jane McElroy; Fiscal Year: 2005
    ..measured Cd and 2) age, geographic location, parity, menopausal status, occupation, consumption of supplemental minerals and food with potentially high Cd levels are related with Cd body burden...
  50. Chromium, Cellular Energy Status and Whole Body Energy Balance
    William Cefalu; Fiscal Year: 2007
    ..data in humans in regard to proposed mechanism of action, and as such, chromium remains as one of the only trace minerals where the mechanism of action is not known...
    Brooke Mossman; Fiscal Year: 2000
    ..Inhalation of the fibrogenic minerals, silica and asbestos, which induce oxidative stress, cause apoptosis, a programmed type of cell death...
  52. Biological Factors for Age-Related Macular Degeneration
    Johanna Seddon; Fiscal Year: 2004
    ..factors for AMD and cataract and includes a randomized trial to assess the effects of antioxidant vitamins and minerals on these diseases. AREDS provides a unique opportunity to test these associations efficiently and prospectively...
  53. LabMaster: food and water intake, activity and metabolic rate
    DANIELLE REED; Fiscal Year: 2009
    ..and fat metabolism;the neural concomitants of nausea and learned taste aversions;the intake and appetite for minerals such as calcium;the effect of inflammation on taste;and genetically engineered mice with compromised or enhanced ..
  54. Medical Food Cocktail for Alzheimer's Disease
    CURT HENDRIX; Fiscal Year: 2006
    ..initial feasibility tests of a medical food cocktail composed of standardized herbal extracts, vitamins, and minerals that are demonstrated in the basic science and clinical medical literature to impact the biochemical and ..
  55. Incorporating Bone Minerals into Orthopaedic Surfaces
    John Kelley; Fiscal Year: 2004
    ..abstract_text> ..
  56. Phytofiltration of Arsenic-Contaminated Drinking Water
    MARK ELLESS; Fiscal Year: 2003
    ..removal capability by varying such important water treatment factors as arsenic valences, water pH, dissolved minerals including iron, sulfur, sodium and calcium compounds, chlorination/fluoridation, intensity and spectrum of light, ..
    WILLARD VISEK; Fiscal Year: 1980
    ..b>Minerals, vitamins and fiber will be supplied at a constant ratio per kilocalorie of dietary energy for all dietary ..
    David Kohn; Fiscal Year: 2007
    ..In the first cycle of this grant, we developed biomimetic materials based on the self-assembly of biological minerals onto organic templates...
    Caren Gundberg; Fiscal Year: 1991
    ..the qualitative and quantitative effects of chronic and acute administration of calcitropic hormones and minerals on circulating osteocalcin in normal and thyroparathyroidectomized rats. 2...
  60. Effect of Calorie Restriction on Infection During Aging
    Gabriel Fernandes; Fiscal Year: 2004
    ..to infection could be due to differences in strains of mice, energy uptake, supplementation of vitamins and minerals or delayed maturity of humoral immunity...
    James Hargrove; Fiscal Year: 2003
    ..Federal advisory panels are called upon to define adequate levels of intake of vitamins, minerals, and other dietary constituents such as choline...
    Shaul Massry; Fiscal Year: 1980
    Four International Workshops on Phosphate and Other Minerals have been organized since 1975. They were supported by various agencies and pharmaceutical companies...
  63. Mechanisms Linking Dairy to Higher Prostate Cancer Risk
    Marilyn Tseng; Fiscal Year: 2006
    ..in relation to dairy foods and nutrients of interest as potential mediators, such as protein, calcium, and other minerals. We will also examine possible effect modification of the dairy-1,25-D association by ethnicity and vitamin D ..
    Laura Hillman; Fiscal Year: 1990
    ..and 1,25(OH)2D, PTH, calcitonin, serum calcium, phosphorus, magnesium, albumin, and alkaline phosphatase, urine minerals, and bone mineral content by photonabsorptiometery...