periodic acid

Summary

Summary: A strong oxidizing agent.

Top Publications

  1. ncbi Glycol-cleavage oxidation
    Arthur S Perlin
    Department of Chemistry, McGill University, Montreal, Canada, PQ H3A 2K6
    Adv Carbohydr Chem Biochem 60:183-250. 2006
  2. ncbi Rebamipide increases mucin-like substance contents and periodic acid Schiff reagent-positive cells density in normal rabbits
    Hiroki Urashima
    Ako Research Institute, Otsuka Pharmaceutical Co, Ltd, Ako, Hyogo, Japan
    J Ocul Pharmacol Ther 28:264-70. 2012
  3. ncbi Class I major histocompatibility complexes loaded by a periodate trigger
    Boris Rodenko
    Division of Cell Biology II, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    J Am Chem Soc 131:12305-13. 2009
  4. ncbi Spectrofluorimetric determination of trace amounts of coenzyme A using a terbium ion-ciprofloxacin complex probe in the presence of periodic acid
    Jing Li
    Department of Chemistry, Shandong Normal University, Jinan, 250014, China
    Anal Bioanal Chem 387:2083-9. 2007
  5. ncbi Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses
    M Okano
    Departments of Otolaryngology and Pathology, Okayama University Medical School, Okayama, Japan
    J Allergy Clin Immunol 108:101-8. 2001
  6. ncbi Immunohistological characterization of mucin epitopes by pre-treatment of gastro-intestinal sections with periodic acid
    J Bara
    Mucin Immunochemistry Laboratory, SDI 6316, Villejuif, France
    J Immunol Methods 149:105-13. 1992
  7. ncbi Use of soybean peroxidase in chemiluminescent enzyme-linked immunosorbent assay
    Ivan Yu Sakharov
    Chemical Enzymology Department, Faculty of Chemistry, The M V Lomonosov Moscow State University, Russia
    J Agric Food Chem 54:1584-7. 2006
  8. ncbi Efficient oxidative decarboxylation of carboxylic acids with sodium periodate catalyzed by supported manganese (III) porphyrin
    Valiollah Mirkhani
    Department of Chemistry, Isfahan University, Isfahan 81744, Iran
    Bioorg Med Chem Lett 13:3433-5. 2003
  9. ncbi Monitoring activation sites on polysaccharides by GC-MS
    John S Kim
    Wyeth Vaccines Research and Development, Sanford, NC 27330, USA
    Anal Biochem 358:136-42. 2006
  10. ncbi Mild and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by a new polystyrene-bound Mn(TPP)Cl
    Majid Moghadam
    Department of Chemistry, Yasouj University, Yasouj 75914 353, Iran
    Bioorg Med Chem Lett 16:2026-30. 2006

Research Grants

Detail Information

Publications249 found, 100 shown here

  1. ncbi Glycol-cleavage oxidation
    Arthur S Perlin
    Department of Chemistry, McGill University, Montreal, Canada, PQ H3A 2K6
    Adv Carbohydr Chem Biochem 60:183-250. 2006
  2. ncbi Rebamipide increases mucin-like substance contents and periodic acid Schiff reagent-positive cells density in normal rabbits
    Hiroki Urashima
    Ako Research Institute, Otsuka Pharmaceutical Co, Ltd, Ako, Hyogo, Japan
    J Ocul Pharmacol Ther 28:264-70. 2012
    The effects of rebamipide on the number of periodic acid Schiff reagent (PAS)-positive cells in the conjunctiva, the mucin content in the cornea and conjunctiva of normal rabbits, and desiccation-induced corneal damage in vivo were ..
  3. ncbi Class I major histocompatibility complexes loaded by a periodate trigger
    Boris Rodenko
    Division of Cell Biology II, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    J Am Chem Soc 131:12305-13. 2009
    ..In addition, this technology will be useful to develop miniaturized assay systems for performing high-throughput screens for natural and unnatural MHC ligands...
  4. ncbi Spectrofluorimetric determination of trace amounts of coenzyme A using a terbium ion-ciprofloxacin complex probe in the presence of periodic acid
    Jing Li
    Department of Chemistry, Shandong Normal University, Jinan, 250014, China
    Anal Bioanal Chem 387:2083-9. 2007
    ..In the presence of periodic acid (H5IO6), CoA can remarkably enhance the fluorescence intensity of the Tb3+-ciprofloxacin (CIP) complex at 545 ..
  5. ncbi Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses
    M Okano
    Departments of Otolaryngology and Pathology, Okayama University Medical School, Okayama, Japan
    J Allergy Clin Immunol 108:101-8. 2001
    ..CONCLUSION: The results suggest that carbohydrates on Cry j 1 play a major role in promoting Cry j 1-specific T(H)2 response in vitro, though they are not major targets as T-cell epitopes...
  6. ncbi Immunohistological characterization of mucin epitopes by pre-treatment of gastro-intestinal sections with periodic acid
    J Bara
    Mucin Immunochemistry Laboratory, SDI 6316, Villejuif, France
    J Immunol Methods 149:105-13. 1992
    ....
  7. ncbi Use of soybean peroxidase in chemiluminescent enzyme-linked immunosorbent assay
    Ivan Yu Sakharov
    Chemical Enzymology Department, Faculty of Chemistry, The M V Lomonosov Moscow State University, Russia
    J Agric Food Chem 54:1584-7. 2006
    ..Application of the soya enzyme allowed the development of the immunoassay with improved sensitivity and a wider linear range...
  8. ncbi Efficient oxidative decarboxylation of carboxylic acids with sodium periodate catalyzed by supported manganese (III) porphyrin
    Valiollah Mirkhani
    Department of Chemistry, Isfahan University, Isfahan 81744, Iran
    Bioorg Med Chem Lett 13:3433-5. 2003
    ....
  9. ncbi Monitoring activation sites on polysaccharides by GC-MS
    John S Kim
    Wyeth Vaccines Research and Development, Sanford, NC 27330, USA
    Anal Biochem 358:136-42. 2006
    ..Samples (100-500 microg) were sequentially oxidized, reduced, methanolyzed, and derivatized in a single reaction vial for routine analysis by GC-MS...
  10. ncbi Mild and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by a new polystyrene-bound Mn(TPP)Cl
    Majid Moghadam
    Department of Chemistry, Yasouj University, Yasouj 75914 353, Iran
    Bioorg Med Chem Lett 16:2026-30. 2006
    ..This heterogeneous catalyst is of great stability and reusability in the oxidation of 1,4-dihydropyridines with sodium periodate without significant loss of its catalytic activity...
  11. ncbi Analysis of protein-linked glycosylation in a sperm-somatic cell adhesion system
    Mark Sutton-Smith
    Division of Molecular Biosciences, Imperial College London, London, SW7 2AZ, UK
    Glycobiology 17:553-67. 2007
    ..The far more abundant presentation of such sequences on rabbit erythrocytes compared with murine eggs could explain why mouse sperm display such exceptional affinity for this somatic cell type...
  12. ncbi Determination of catecholamines by CE with direct chemiluminescence detection
    Yan Ming Liu
    College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang, PR China
    Electrophoresis 28:1937-41. 2007
    ..The results obtained indicate that there is a close relationship between the content of dopamine in human urine and the amount of cigarettes smoked daily; the level of dopamine in smokers is higher than in nonsmokers...
  13. ncbi Determination of picomole amounts of thiamine through flow-injection analysis based on the suppression of luminol-KIO(4) chemiluminescence system
    Zhenghua Song
    Department of Chemistry, Northwest University, Xi an, 710069, Xi an, People s Republic of China
    J Pharm Biomed Anal 28:683-91. 2002
    ..0%. The flow sensor showed remarkable stability and could be easily reused over 80 h. The sensor proposed was tested in determination of thiamine in pharmaceutical preparation and human urine samples...
  14. ncbi Structural investigation of a heteropolysaccharide isolated from the pods (fruits) of Moringa oleifera (Sajina)
    Sadhan K Roy
    Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, West Bengal, India
    Carbohydr Res 342:2380-9. 2007
    ..On the basis of total hydrolysis, methylation analysis, periodate oxidation, and NMR ((1)H, (13)C, TOCSY, DQF-COSY, NOESY, ROESY, HSQC, and HMBC) studies, the repeating unit of the polysaccharide is established as [structure: see text]...
  15. ncbi Bis(trimethylsilyl)chromate catalyzed oxidations of alcohols to aldehydes and ketones with periodic acid
    Karim Asadolah
    Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran
    Molecules 12:958-64. 2007
    A facile, selective and high yielding bis(trimethylsilyl) chromate (BTSC) catalyzed selective oxidation of alcohols to aldehydes and ketones with periodic acid is reported.
  16. ncbi Comparison of Neisseria meningitidis serogroup W135 polysaccharide-tetanus toxoid conjugate vaccines made by periodate activation of O-acetylated, non-O-acetylated and chemically de-O-acetylated polysaccharide
    Seshu K Gudlavalleti
    Laboratory of Bacterial Polysaccharides, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Vaccine 25:7972-80. 2007
    ..Thus, for W135, PS O-acetylation does not contribute a dominant immunogenic epitope. The OAc(-) PS may be a good starting material for preparing W135 PS-TT conjugate vaccines using periodate oxidation...
  17. ncbi Structural determination of a neutral exopolysaccharide produced by Lactobacillus delbrueckii ssp. bulgaricus LBB.B332
    Inmaculada Sánchez-Medina
    Bijvoet Center, Department of Bio Organic Chemistry, Utrecht University, Padualaan 8, NL 3584 CH Utrecht, The Netherlands
    Carbohydr Res 342:2735-44. 2007
    ....
  18. ncbi The structure of a polysaccharide from infectious strains of Burkholderia cepacia
    A Linker
    Veterans Affairs (VA, Salt Lake City Health Care System, 500 Foothill Boulevard (151E, Salt Lake City, UT 84124, USA
    Carbohydr Res 335:45-54. 2001
    ..About three O-acetyl groups per repeating unit are present at undetermined positions...
  19. ncbi Structural analysis of the alpha-D-glucan (EPS180) produced by the Lactobacillus reuteri strain 180 glucansucrase GTF180 enzyme
    Sander S van Leeuwen
    Bijvoet Center, Department of Bio Organic Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Carbohydr Res 343:1237-50. 2008
    ....
  20. ncbi Analysis of glycan structures on the 120 kDa aminopeptidase N of Manduca sexta and their interactions with Bacillus thuringiensis Cry1Ac toxin
    Peter J K Knight
    Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, BC, Canada V6T 1Z4
    Insect Biochem Mol Biol 34:101-12. 2004
    ..It is likely that 5-6 of the 13 sites are occupied, probably with simple [GalNAc-peptide] type O-glycans. This O-glycosylated C-terminal stalk, being GalNAc-rich, is the most likely binding site for Cry1Ac...
  21. ncbi A simple and high sensitive spectrophotometric method for ultra trace determination of ruthenium with its catalytic effect on the oxidation of pyronin B by periodate
    Behzad Rezaei
    Department of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
    Spectrochim Acta A Mol Biomol Spectrosc 66:869-73. 2007
    ..The precision, expressed as relative standard deviation of three measurements, is better than 2.44%...
  22. ncbi Efficient and selective hydrocarbon oxidation with sodium periodate under ultrasonic irradiation catalyzed by polystyrene-bound Mn (TPyP)
    Shahram Tangestaninejad
    Department of Chemistry, Isfahan University, Isfahan 81744, Iran
    Ultrason Sonochem 13:32-6. 2006
    ..Under mild reaction conditions, this catalyst was consecutive reused five times without detectable catalyst leaching and gave over 95% epoxide yield in the epoxidation of styrene...
  23. ncbi Simple fluorimetric method for determination of certain antiviral drugs via their oxidation with cerium (IV)
    Ibrahim A Darwish
    Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
    Farmaco 60:555-62. 2005
    ..2 to 101.2+/-0.48-1.30%. The results obtained by the proposed fluorimetric method were comparable with those obtained by the official method stated in the United States Pharmacopoeia...
  24. ncbi Biomimetic oxidation of Hantzsch 1,4-dihydropyridines with tetra-n-butylammonium periodate catalyzed by tetraphenylporphyrinatomanganese(III) chloride [Mn(TPP)Cl]
    Masoud Nasr-Esfahani
    Department of Chemistry, Yasouj University, Yasouj 75914 353, Iran
    Bioorg Med Chem Lett 15:3276-8. 2005
    ..This catalytic system shows high efficiency in the oxidation of 1,4-dihydropyridines at room temperature in the presence of imidazole...
  25. ncbi Carbohydrate-specifically polyethylene glycol-modified ricin A-chain with improved therapeutic potential
    Yu Seok Youn
    Drug Targeting Laboratory, College of Pharmacy, Sungkyunkwan University, 300 Chonchon dong, Jangan ku, Suwon City 440 746, South Korea
    Int J Biochem Cell Biol 37:1525-33. 2005
    ..Therefore, these results suggest that the therapeutic use of immunotoxins constructed using this carbohydrate-specifically PEGylated ricin A-chain has potential as a cancer therapy...
  26. ncbi Kinetic spectrophotometric determination of rutin by its inhibitory effect on the oxidation of amaranth by potassium periodate
    Shuhao Wang
    College of Environmental Science and Engineering, Donghua University, Shanghai 200051, PR China
    Ann Chim 95:87-94. 2005
    ..02 - 0.50 microg/ml, and the detection limit is 0.014 microg/ml. The method has been successfully applied to the determination of rutin in medicine of rutin tablet and traditional Chinese medicine...
  27. ncbi Mild and efficient oxidation of alcohols with sodium periodate catalyzed by polystyrene-bound Mn(III)porphyrin
    Majid Moghadam
    Department of Chemistry, Yasouj University, Yasouj 75914 353, Iran
    Bioorg Med Chem 13:2901-5. 2005
    ..This catalyst can be reused consecutively four times in the oxidation of 4-chlorobenzyl alcohol in 97% yield without significant loss of its activity...
  28. ncbi Determination of manganese in some medicinal plants and their infusions by a catalytic spectrophotometric method
    Konstantin Mutaftchiev
    Department of Chemistry and Biochemistry, Higher Medical Institute 5800 Pleven, Bulgaria
    Ann Chim 94:829-36. 2004
    ..The method was applied successfully to the determination of total manganese in some medicinal plants and to analyse their infusions for trace amounts of total manganese and free manganese (II) ions without separation...
  29. ncbi Immunogenic comparison of two coupling methods of marine polysaccharide to bovine serum albumin
    Li Gan
    Department of Pharmacology, Marine Drug and Food Institute, Ocean University of China, Qingdao, PR China
    Biol Pharm Bull 27:1532-6. 2004
    ..A mouse immunized with MPS-BSAr was chosen to prepare monoclonal antibodies (mAbs) specific for polysaccharide MPS. A hybridoma cell line that secreted monoclonal antibody recognizing specifically polysaccharide MPS was established...
  30. ncbi Structural analysis of water-soluble glucans from the root of Angelica sinensis (Oliv.) Diels
    Wei Cao
    Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi an, China
    Carbohydr Res 341:1870-7. 2006
    ..Such glucans isolated from A. sinensis (Oliv.) Diels have not been previously reported...
  31. ncbi Cytochrome P-450 dependent monooxygenases model system: rapid and efficient oxidation of primary aromatic amines to azo derivatives with sodium periodate catalyzed by manganese(III) Schiff base complexes
    Valiollah Mirkhani
    Department of Chemistry, Isfahan University, Isfahan 81746 73441, Iran
    Bioorg Med Chem 12:4673-7. 2004
    ..Mn(III)-salophen catalyst can catalyze the oxidation of primary aromatic amines to azo derivatives with sodium periodate. The ability of various Schiff base complexes in this oxidation system was also investigated...
  32. ncbi Screening of carbohydrate-specific phage antibodies against recombinant human erythropoietin (rhuEPO) using a phage display antibody library: preliminary study
    Jiebo Mi
    Institute of Analytical Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100 871, PR China
    J Immunoassay Immunochem 27:115-28. 2006
    ..These phage antibodies may serve as useful capture ligands for future development of efficient analytical methods for rHuEPO...
  33. ncbi Repetitive determination of chemical oxygen demand by cyclic flow injection analysis using on-line regeneration of consumed permanganate
    Michio Zenki
    Department of Chemistry, Okayama University of Science, 1 1, Ridai cho, Okayama 700 0005, Japan
    Anal Sci 22:77-80. 2006
    ..The obtained COD values with the proposed method were co-related with those provided by the manual standard method, but were fairly low owing to the insufficient digestion step...
  34. ncbi Highly selective spectrophotometric flow-injection determination of trace amounts of bromide by catalytic effect on the oxidation of m-cresolsulfonephthalein by periodate
    Ali A Ensafi
    College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
    Spectrochim Acta A Mol Biomol Spectrosc 60:2053-7. 2004
    ..1%. The influence of potential interfering ions on the selectivity was studied. The method successes to measure bromide in the presence of other halide ions. The method was used to measure bromide in river water and tap water...
  35. ncbi Improved pharmacological properties for superoxide dismutase modified with mannan
    Aymara Valdivia
    Center for Enzyme Technology, University of Matanzas, Autopista a Varadero km 3 1 2, Matanzas, C P 44740, Cuba
    Biotechnol Appl Biochem 44:159-65. 2006
    ..The anti-inflammatory activity of SOD was increased 2-fold and its plasma half-life time was prolonged from 4.8 min to 1.7 h after glycosylation with the polymer...
  36. ncbi Structural investigation of a polysaccharide (Fr. I) isolated from the aqueous extract of an edible mushroom, Volvariella diplasia
    Kaushik Ghosh
    Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721 102, West Bengal, India
    Carbohydr Res 343:1071-8. 2008
    ....
  37. ncbi Structural assignment of a heteropolysaccharide isolated from the gum of Cochlospermum religiosum (Katira gum)
    Arnab K Ojha
    Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India
    Carbohydr Res 343:1222-31. 2008
    ....
  38. ncbi Simultaneous determination of trace iron and aluminum by catalytic spectrophotometry based on a novel oxidation reaction of xylene cyanol FF
    Longfei Cai
    Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University
    Anal Sci 24:775-8. 2008
    ..The method was applied to the simultaneous determination of trace Fe and Al in tap water, lake water, river water and tea leaves without separation and preconcentration...
  39. ncbi Binding patterns of 51 monoclonal antibodies to peptide and carbohydrate epitopes of the epithelial mucin (MUC1) on tissue sections of adenolymphomas of the parotid (Warthin's tumours): role of epitope masking by glycans
    Y Cao
    , , 13125 Berlin-Buch, Germany
    Histochem Cell Biol 115:349-56. 2001
    ..The carcinoma-associated Thomsen-Friedenreich epitope was absent...
  40. ncbi A new green analytical procedure for monitoring sub-nanogram amounts of chlorpyrifos on fruits using flow injection chemiluminescence with immobilized reagents
    Zhenghua Song
    Department of Chemistry, Northwest University, Xi an 710069, People s Republic of China
    J Agric Food Chem 50:4468-74. 2002
    ..4-107.4%. The change of the concentration of chlorpyrifos in a water sample was also investigated, and the variation rate was 99.96% during 35 h in the open air...
  41. ncbi In vitro monitoring sub-nanogram amounts analgin in human urine by its inhibitory of the luminol-periodate chemiluminescence reaction using reagent immobilization release technique
    Zhenghua Song
    Department of Chemistry, Northwest University, Xi an 710069, China
    Bioorg Med Chem 10:2091-7. 2002
    ..28% in the body of volunteers. The flow sensor offered reagentless procedures and remarkable stability in determination of analgin, and could be easily reused over 80 h...
  42. ncbi Flow-injection chemiluminescence sensor for determination of isoniazid in urine sample based on molecularly imprinted polymer
    Yan Xiong
    Institute of Analytical Science, Department of Chemistry, Southwest China University, Beibei, Chongqing 400715, PR China
    Spectrochim Acta A Mol Biomol Spectrosc 66:341-6. 2007
    ..At the same time, the binding characteristic of the polymer to isoniazid was evaluated by batch method and the dynamic method, respectively...
  43. ncbi Determination of ampicillin and amoxycillin by flow injection chemiluminescence method based on their enhancing effects on the luminol-periodate reaction
    Yinhuan Li
    Department of Chemistry, School of Science, Xi an Jiaotong University, 710049, People s Republic of China
    Luminescence 18:313-7. 2003
    ..The method was successfully applied to the determination of ampicillin and amoxycillin in pharmaceutical preparations. A brief discussion on the possible chemiluminescence reaction mechanism is presented...
  44. ncbi Flow-injection chemiluminescence determination of catecholamines based on their enhancing effects on the luminol-potassium periodate system
    Hong Yao
    Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou 350004, People s Republic of China
    Luminescence 21:112-7. 2006
    ..The present method was successfully applied to the determination of the four catecholamines in pharmaceutical injections...
  45. ncbi Inhibition and enhancement by organic compounds of luminol-KIO4-H2O2 chemiluminescence
    Hong Xu
    Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, People s Republic of China
    Luminescence 21:195-201. 2006
    ..Based on the CL inhibition or enhancement, the possibility of analytical applications was explored. The results demonstrated that numerous compounds were detectable at the ng/mL level using the CL system...
  46. ncbi A monoclonal antibody, PGM34, against 6-sulfated blood-group H type 2 antigen, on the carbohydrate moiety of mucin
    Daigo Tsubokawa
    Department of Biochemistry, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
    FEBS J 274:1833-48. 2007
    ..These data, taken together, show that PGM34 is a very useful tool for elucidating the role of mucins with characteristic sulfated oligosaccharides...
  47. ncbi Covalently-bound heparin makes collagen thromboresistant
    Jeffrey F W Keuren
    Department of Biochemistry, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 24:613-7. 2004
    ..However, the thrombogenic nature of collagen limits its application. We examined whether heparinization can make collagen more thromboresistant...
  48. ncbi Fluorescent staining of glycoproteins on polyvinylidene difluoride membrane with 8-aminonaphthalene-1,3,6-trisulfonate
    F Y Che
    Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai, 200031, PRC
    Biotechniques 30:1272-6, 1278. 2001
    ..We used periodic acid oxidation of carbohydrate chains of glycoproteins and fluorescent labeling with 8-aminonaphthalene-1,3,6-..
  49. pmc Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside
    Koen Nauwelaerts
    Rega Institute for Medical Research, Laboratory for Medicinal Chemistry, Minderbroedersstraat 10, B 3000 Leuven, Belgium
    Nucleic Acids Res 31:6758-69. 2003
    ..As a result of this, an intact natural oligodeoxynucleotide is obtained after ligation reaction, which means that site-specific cleavage and recovering of intact DNA occurs without loss of genetic information...
  50. ncbi Synthesis and evaluation of ampicillin-conjugated gum arabic microspheres for sustained release
    K K Nishi
    Division of Polymer Chemistry, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Satelmond Palace Campus, Trivandrum, Kerala 695 012, India
    J Pharm Pharmacol 59:485-93. 2007
    ..These studies show that ampicillin conjugated with oxidized GA and fabricated into microspheres possesses sustained-release characteristics for prolonged periods...
  51. ncbi Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytes
    Kaori Inoue
    Shiseido Research Center, Kanazawa Ku, Yokohama, Japan
    J Invest Dermatol 127:362-71. 2007
    ..Furthermore, in UVB-radiated cells, we note the possibility that P2 receptor antagonists may reduce skin inflammation...
  52. ncbi Surface engineering of living myoblasts via selective periodate oxidation
    P A De Bank
    School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom
    Biotechnol Bioeng 81:800-8. 2003
    ..These data indicate that sodium periodate treatment is an effective, noncytotoxic method for the in vitro molecular engineering of living cell surfaces with the potential for cell biology and tissue engineering applications...
  53. ncbi Indospicine as an arginine antagonist in Escherichia coli and Pseudomonas aeruginosa
    T Lesinger
    Biochim Biophys Acta 262:214-9. 1972
  54. ncbi Head-to-tail cyclized cystine-knot peptides by a combined recombinant and chemical route of synthesis
    Olga Avrutina
    Institut fur Organische Chemie und Biochemie, TU Darmstadt, Petersenstrasse 22, 64287 Darmstadt, Germany
    Chembiochem 9:33-7. 2008
  55. ncbi Immunohistochemical artifact for nitrotyrosine in eosinophils or eosinophil containing tissue
    Keiki Ogino
    Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, 13 1 Takaramachi, Kanazawa, Japan
    Free Radic Res 36:1163-70. 2002
    ....
  56. ncbi Cyclodextrin-grafted polysaccharides as supramolecular carrier systems for naproxen
    Héctor L Ramirez
    Enzyme Technology Group, University of Matanzas, Matanzas 44740, Cuba
    Bioorg Med Chem Lett 16:1499-501. 2006
    ..These polymers were used as supramolecular carriers for naproxen, improving the "in vivo" anti-inflammatory properties of this drug...
  57. ncbi Binding patterns of DTR-specific antibodies reveal a glycosylation-conditioned tumor-specific epitope of the epithelial mucin (MUC1)
    Uwe Karsten
    NEMOD GmbH and Co KG, Robert Rossle Str 10, D 13125 Berlin, Germany
    Glycobiology 14:681-92. 2004
    ..PDTRP... sequence in a particular conformation essentially determined by O-glycosylation at its threonine with either GalNAcalpha1 or a related short glycan. The results can find application in the field of MUC1-based immunotherapy...
  58. pmc Dendritic cell-dependent inhibition of B cell proliferation requires CD22
    Lorna Santos
    Department of Immunology, University of Washington, Seattle, WA 98195, USA
    J Immunol 180:4561-9. 2008
    ..The alpha2,6-sialic acid-containing glycoprotein is important for splenic B cell subset development, whereas the DC-associated ST6Gal-I-independent CD22L may be required for the maintenance of long-lived mature B cells in the BM...
  59. ncbi Quantitative determination of paralytic shellfish poisoning toxins in shellfish using prechromatographic oxidation and liquid chromatography with fluorescence detection: interlaboratory study
    James F Lawrence
    Health Canada, Food Research Division, Bureau of Chemical Safety, Food Directorate, Banting Research Centre 2203D, Ottawa, ON, K1A 0L2, Canada
    J AOAC Int 87:83-100. 2004
    ..Twenty-one samples in total were sent to 21 collaborators who agreed to participate in the study. Results were obtained from 18 laboratories representing 14 different countries...
  60. ncbi A dopaquinone model that mimics the water addition step of cofactor biogenesis in copper amine oxidases
    Ke Qing Ling
    Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA
    J Am Chem Soc 127:4777-84. 2005
    ..This study represents the first chemical demonstration of a true o-quinone hydration, which occurs in cofactor biogenesis in copper amine oxidases...
  61. ncbi Dextran and 5-aminosalicylic acid (5-ASA) conjugates: synthesis, characterisation and enzymic hydrolysis
    Shavej Ahmad
    Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow G4 0BA, United Kingdom
    Carbohydr Res 341:2694-701. 2006
    ..1mg per 100mg of product) but were successfully hydrolysed by dextranase, suggesting their potential applications for the treatment of Crohn's disease in the distal ileum and proximal colon...
  62. ncbi Morphologic characterization of spontaneous nervous system tumors in mice and rats
    G J Krinke
    Toxicology Department, Novartis Crop Protection AG, Stein, Switzerland
    Toxicol Pathol 28:178-92. 2000
    ..to be totally or at least partly composed of granular cells, which have eosinophilic granular cytoplasm, are periodic acid-Schiff reaction (PAS)-positive, and contain lysosomes...
  63. ncbi [Effects of glucocorticoid on airway mucus secretion in asthma: experiment with asthmatic mouse model]
    Jian bo Liu
    Department of Respiratory Disease, Second Affiliated Hospital, Zhengzhou University, Zhengzhou, China
    Zhonghua Yi Xue Za Zhi 86:2491-4. 2006
    ..To study the effects of glucocorticoid on airway mucus secretion in asthma...
  64. ncbi Mycophenolic acid (cellcept and myofortic) induced injury of the upper GI tract
    Thong Nguyen
    Department of Pathology, Johns Hopkins Hospital, Johns Hopkins University, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 33:1355-63. 2009
    ..We studied the pattern of upper GI tract injury in symptomatic patients taking MPA...
  65. ncbi Spontaneous remission of edema and regranulation of goblet cells in rat tracheae after capsaicin-induced acute inflammation
    Jin Jang Guo
    Department of Biological Sciences, National Sun Yat Sen University, Kaohsiung, Taiwan
    Anat Embryol (Berl) 206:301-9. 2003
    ..with chloroacetate esterase reagent and Alcian blue and tracheal tissue sections stained with Alcian blue and periodic acid-Schiff reagent were used for evaluation...
  66. ncbi Staining methods applied to glycol methacrylate embedded tissue sections
    P S Cerri
    Department of Morphology, Dental School, Sao Paulo State University UNESP, Rua Humaita 1680, Araraquara 14 801 903, SP, Brazil
    Micron 34:365-72. 2003
    ..b>Periodic Acid-Schiff (PAS) method was used for detection of glycoconjugates in submandibular gland and cartilage while AB/..
  67. ncbi [Effects of phosphodiesterase-4 inhibitor on the mucin secretion in airway stimulated with acrolein: experiment with rats]
    Xun Wang
    Division of Pulmonary Diseases, National Key Laboratory of Biotherapy of Human Diseases, Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu 610041, China
    Zhonghua Yi Xue Za Zhi 88:2988-93. 2008
    ..To examine the effects of YM976, a phosphodiesterase (PDE)4 inhibitor, on mucin hypersecretion of airway stimulated with acrolein...
  68. ncbi Histochemical analysis of glycoconjugates in the skin of a catfish (arius tenuispinis, day)
    A Al-Banaw
    Medical Laboratory Sciences Department, Kuwait University, Sulaibekhat, Kuwait
    Anat Histol Embryol 39:42-50. 2010
    ..From these data, we can conclude that the mucus produced by the epidermal goblet cells of A. tenuispinis is rich in mannose, N-acetylgalactosamine and N-acetylglucosamine residues...
  69. ncbi Role of Helicobacter pylori in gastric carcinoma
    S R Prabhu
    Topiwala National Medical College, Bombay, Maharashtra, India
    Natl Med J India 8:58-60. 1995
    ..metaplasia and presence of Helicobacter pylori were assessed by staining with haematoxylin and eosin, periodic acid-Schiff reagent with alcian blue and Warthin-Starry stains. RESULTS...
  70. ncbi Increased expression of human calcium-activated chloride channel 1 is correlated with mucus overproduction in the airways of Chinese patients with chronic obstructive pulmonary disease
    Ke Wang
    Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu 610041, China
    Chin Med J (Engl) 120:1051-7. 2007
    ..To investigate the relationship of CaCC(1) and mucus overproduction in the airway of Chinese patients with COPD, the expressions of CaCC(1), MUC5AC and mucus in bronchial tissues were examined...
  71. ncbi Lymphocytic infiltration and goblet cell marker alteration in the conjunctiva of the MRL/MpJ-Fas(lpr) mouse model of Sjögren's syndrome
    Yolanda Diebold
    Schepens Eye Research Institute Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Exp Eye Res 84:500-12. 2007
    ..Left eyes were fixed, embedded, sectioned, and stained. Hematoxylin/eosin, Giemsa, or alcian blue/periodic acid Schiff's reagent were used to study lymphocyte infiltration; to determine the presence of eosinophils, ..
  72. ncbi Histopathologic evaluation of an animal model for Barrett's esophagus and adenocarcinoma of the distal esophagus
    Christianne J Buskens
    Department of Surgery, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    J Surg Res 135:337-44. 2006
    ....
  73. ncbi Microsporidia in the small intestine of HIV-infected patients. A new diagnostic technique and a new species
    A S Field
    St Vincent s Hospital, Darlinghurst, NSW
    Med J Aust 158:390-4. 1993
    ..To determine whether microsporidian infections occur in Australian patients infected with human immunodeficiency virus (HIV), to assess the incidence, and to discuss microscopic detection methods...
  74. ncbi Glyconjugates in epidermal, branchial and digestive mucous cells and gastric glands of gilthead sea bream, Sparus aurata, Senegal sole, Solea senegalensis and Siberian sturgeon, Acipenser baeri development
    C Sarasquete
    Instituto de Ciencias Marinas de Andalucia, CSIC, Puerto Real, Cadiz, Spain
    Eur J Histochem 45:267-78. 2001
    ..fish species (two teleostean and a chondrostean) were investigated using conventional histochemical methods (periodic acid schiff -PAS-, diastase-PAS; alcian blue pH 0.5, 1 and 2...
  75. ncbi [Changes of myocardial enzymes related to glycolysis and fatty acid metabolism in chronic myocardial ischemia: experiment with pigs]
    Jing Gong
    Department of Pathophysiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
    Zhonghua Yi Xue Za Zhi 88:2209-13. 2008
    ....
  76. ncbi Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification
    Shamila Mauiyyedi
    Pathology Service, Immunopathology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Soc Nephrol 13:779-87. 2002
    ..Hematoxylin and eosin and periodic acid-Schiff stained sections were scored for glomerular, vascular, and tubulointerstitial pathology...
  77. ncbi Erythema gyratum repens-like psoriasis
    S Jablonska
    Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland
    Int J Dermatol 39:695-7. 2000
    ..b>Periodic acid-Schiff (PAS) and other stains for mycotic infection were negative...
  78. ncbi Ultrastructure and histochemical study of glycoconjugates in the gills of the white croaker (Micropogonias furnieri)
    A O Diaz
    Departamento de Biologia, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, Funes 3250, 3er Piso 7600 Mar del Plata, Argentina
    Anat Histol Embryol 34:117-22. 2005
    ..Neutral sugars and substituted sialic acid were detected by means of periodic acid-borohydride reduction-saponification-periodic acid Schiff reaction (PA/Bh/KOH/PAS), saponification-selective ..
  79. ncbi Characteristics of nonmalignant and malignant human prostate in organ culture
    J Varani
    Department of Pathology, University of Michigan Medical School, Ann Arbor 48109, USA
    Lab Invest 79:723-31. 1999
    ..Staining with the Periodic Acid Schiff (PAS) and PAS-methenamine silver (PASME) reagents revealed an intact basement membrane around virtually ..
  80. ncbi Transforming growth factor β inducible apoptotic cascade in epithelial cells during rat molar tooth eruptions
    Mitsuko Moriguchi
    Department of Ultrastructural Science, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba, 261 8502, Japan
    Anat Sci Int 85:92-101. 2010
    ..We also performed periodic acid Schiff (PAS) reaction and terminal deoxynucleotidyl transferase-mediated dUTD nick end labeling (TUNEL) ..
  81. ncbi Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease
    Ke Wang
    Division of Pulmonary Diseases, State Key Laboratory of Biotherapy of China, and Department of Respiratory Medicine, West China Hospital of Sichuan University, Sichuan, China
    Acta Pharmacol Sin 28:1166-74. 2007
    ..To investigate the relationship between aquaporin-5 (AQP5) expression and mucus overproduction in the airways of Chinese patients with chronic obstructive pulmonary disease (COPD) and the correlation with pulmonary function change...
  82. ncbi Qualitative tear film and conjunctival goblet cell assessment of cats with corneal sequestra
    Bruce H Grahn
    Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    Vet Ophthalmol 8:167-70. 2005
    ..biopsies were fixed in formalin and sectioned routinely and stained with hematoxylin and eosin, and periodic acid-Schiff. These slides were examined by light microscopy by a blinded examiner...
  83. ncbi Germinal epithelium, folliculogenesis, and postovulatory follicles in ovaries of rainbow trout, Oncorhynchus mykiss (Walbaum, 1792) (Teleostei, protacanthopterygii, salmoniformes)
    Harry J Grier
    Division of Fishes, Department of Vertebrate Zoology, National Museum of Natural History, Smithsonian Institution, Washington, District of Columbia 20013 7012, USA
    J Morphol 268:293-310. 2007
    ..After ovulation, the ovaries of postspawned rainbow trout were examined histologically, using the periodic acid-Schiff procedure, to stain basement membranes that subtend the germinal epithelium and to interpret and define ..
  84. ncbi Translocation of Salmonella typhimurium in rats on total parenteral nutrition correlates with changes in intestinal morphology and mucus gel
    Ken ichi Sakamoto
    First Department of Surgery, Gifu University School of Medicine, Gifu, Japan
    Nutrition 20:372-6. 2004
    ..We tested whether alterations in intestinal morphology and mucus gel correlate with differences in Salmonella typhimurium translocation between rats treated with total parenteral nutrition (TPN) and rats given a diet of chow...
  85. ncbi Tissue quantification of neutral and acid mucins in the mucosa of the colon with and without fecal stream in rats
    Ronaldo Nonose
    Program in Health Sciences, USF, Braganca Paulista, SP, Brazil
    Acta Cir Bras 24:267-75. 2009
    ..To quantify the intensity of the expression of neutral and acids mucins in mucosa of the colon with and without fecal stream and to correlate this with the duration of fecal transit diversion...
  86. ncbi Spatiotemporal distribution patterns of oligosaccharides during early embryogenesis in the starfish Patiria pectinifera
    Takuya Doihara
    Department of Anatomy and Embryology, Ehime University Graduate School of Medicine, Tohon, Ehime, Japan
    Dev Genes Evol 219:199-206. 2009
    ..we histochemically analyzed several larval stages using Alcian Blue (AB, which stains acidic mucins), Periodic Acid Schiff (PAS, which stains neutral mucins), and 21 types of lectins...
  87. ncbi Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment
    J D Miller
    Department of Chemistry, Carleton University, Ottawa, Ontario, Canada K1S 5B6
    Chem Biol Interact 183:113-24. 2010
    ..Hematoxylin and eosin (H&E) histology and Alcian Blue/Periodic Acid Schiff (AB/PAS) histochemistry were used to evaluate lungs for time course (4h and 12h post-exposure (PE)) ..
  88. pmc Keratoconus associated with corneal stromal amyloid deposition containing TGFBIp
    Tak Yee Tania Tai
    The Jules Stein Eye Institute, David Geffen School of Medicine, The University of California at Los Angeles, Los Angeles, CA 90095, USA
    Cornea 28:589-93. 2009
    ..To report the identification and characterization of stromal amyloid deposits in patients with keratoconus...
  89. ncbi Erdheim-Chester disease with cutaneous features in an Indian patient
    Taru Garg
    Department of Dermatology, Venereology and Leprosy Lady Hardinge Medical College, New Delhi, India
    Skinmed 7:103-6. 2008
    ..The foamy histiocytes were periodic acid-Schiff-positive. On immunohistochemistry, histiocytes were CD68-positive...
  90. ncbi Paget cells in the esophagus: assessment of their histopathologic features and near-universal association with underlying esophageal adenocarcinoma
    Susan C Abraham
    Department of Pathology, M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 32:1068-74. 2008
    ..Histochemistry for periodic acid-Schiff with diastase (PAS-D) and mucicarmine, and immunohistochemistry for CK7, CK20, p53, and E-cadherin, ..
  91. ncbi The effect of calcium channel blocker verapamil on gentamicin nephrotoxicity in rats
    Nenad Stojiljkovic
    Department of Physiology, Faculty of Medicine, University of Nis, Nis, Serbia
    Bosn J Basic Med Sci 8:170-6. 2008
    ..Histological examinations were done using hematoxylin and eosin, periodic acid Schiff and methenamine silver staining methods...
  92. ncbi Pulmonary alveolar proteinosis: a spectrum of cytologic, histochemical, and ultrastructural findings in bronchoalveolar lavage fluid
    S J Maygarden
    Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7525, USA
    Diagn Cytopathol 24:389-95. 2001
    Pulmonary alveolar proteinosis (PAP) is defined as abundant extracellular proteinaceous periodic acid-Schiff (PAS)-positive material which represents surfactant distending alveolar spaces...
  93. ncbi Effects of weaning and infection with Teladorsagia circumcincta on mucin carbohydrate profiles of early weaned lambs
    V C Hoang
    Institute of Veterinary Animals and Biomedical Sciences, Massey University, Palmerston North, New Zealand
    Vet Parasitol 171:354-60. 2010
    ..monosaccharides were analysed chemically and fundic, antral and duodenal tissues were stained with lectins, periodic acid Schiff (PAS), Alcian blue/PAS (AB/PAS) and high iron diamine...
  94. ncbi The glycosylation status of murine [corrected] postnatal thymus: a study by histochemistry and lectin blotting
    Erdal Balcan
    Department of Biology, Faculty of Science and Art, Celal Bayar University, Molecular Biology Sect 45047 Muradiye Campus, Manisa, Turkey
    J Mol Histol 39:417-26. 2008
    ..With alcian blue (AB) at pH 5.7/periodic acid-Schiff (PAS) stainings, it was shown that thymic microenvironments contained carboxlylated and sulfated ..
  95. ncbi The cyclin kinase inhibitor p21CIP1/WAF1 limits glomerular epithelial cell proliferation in experimental glomerulonephritis
    Y G Kim
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Kidney Int 55:2349-61. 1999
    ..Cell proliferation is controlled by cell-cycle regulatory proteins where the cyclin-dependent kinase inhibitor p21Cip1,WAF1 (p21) inhibits cell proliferation and is required for differentiation of many nonrenal cell types...
  96. ncbi Changes in angiopoietin expression in glomeruli involved in glomerulosclerosis in rats with daunorubicin-induced nephrosis
    Yuan Hang Lu
    Department of Nephrology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Acta Pharmacol Sin 27:579-87. 2006
    ..To study the potential pathological role of endogenous angiopoietins in daunorubicin-induced progressive glomerulosclerosis in rats...
  97. ncbi Changes of gill and hemocyte-related bio-indicators during long term maintenance of the vent mussel Bathymodiolus azoricus held in aquaria at atmospheric pressure
    Raul Bettencourt
    IMAR Department of Oceanography and Fisheries, Genetics and Molecular Biology Laboratory, University of the Azores, Rua Comendador Fernando da Costa, 9901 862 Horta, Portugal
    Comp Biochem Physiol A Mol Integr Physiol 150:1-7. 2008
    ..or glycoprotein was made possible through their inherent auto-fluorescent property and the Alcian blue-Periodic Acid Schiff staining method...
  98. ncbi Optimized quality of histologic images allows the use of neural network scanning in diagnosis of fungal infection of abnormal nails
    Mathilde E Boon
    Leiden Cytology and Pathology Laboratory, Leiden, The Netherlands
    Anal Quant Cytol Histol 28:78-86. 2006
    ....
  99. ncbi Vascular changes in erythropoietic protoporphyria: histopathologic and immunohistochemical study
    K Timonen
    Department of Dermatology, Divisions of Endocrinology and Nephrology, University Hospital of Helsinki, Finland
    J Am Acad Dermatol 43:489-97. 2000
    ..RESULTS: The characteristic finding was thickened, periodic acid-Schiff-positive vessel walls caused by concentric reduplication of basal lamina and excess of fine granular ..
  100. ncbi [Expressions of PDCD5 and other apoptosis-related proteins in muscle of patients with mitochondrial cytopathy]
    Yong fie Li
    Department of Neurology, First Hospital, Peking University, Beijing, China
    Zhonghua Yi Xue Za Zhi 89:1593-6. 2009
    ....
  101. ncbi Kerion and dermatophytic granuloma. Mycological and histopathological findings in 19 children with inflammatory tinea capitis of the scalp
    Roberto Arenas
    Dermatology Department, Manuel Gea Gonzalez General Hospital, Mexico City, Mexico
    Int J Dermatol 45:215-9. 2006
    ..Inflammatory tinea capitis or kerion is the result of a hypersensitivity reaction to a dermatophytic infection. Majocchi's granuloma, in contrast, usually begins as a suppurative folliculitis and culminates in a granulomatous reaction...

Research Grants25

  1. The role of NFAT in podocyte damage and proteinuric kidney disease
    ALEXIS JOANNA SLOAN; Fiscal Year: 2013
    ..the glomerulus appears normal under histological techniques such as hematoxylin and eosin (H+E) staining and periodic acid Schiff staining (PAS)...
  2. RESISTANCE--PATHOGENIC NAELERIA TO MO CYTOLYTIC FACTORS
    Francine Marciano Cabral; Fiscal Year: 1991
    ..Lectin precipitation of 125 I-surface labeled proteins followed by SDS-PAGE and staining with Periodic Acid Schiff reagent or sudan black will permit identification of surface glycoproteins or glycolipids...
  3. MYOCARDIAL GLYCOPROTEINS IN NORMAL AND DIABETIC STATES
    MARY SPIRO; Fiscal Year: 1992
    ..This condition, termed diabetic cardiomyopathy, is characterized by the accumulation of periodic acid-Schiff reactive material around muscle fibers and small blood vessels; the nature and source of the ..
  4. SQUAMOUS EPITHELIAL CELL INVASION IN ORGAN CULTURE
    James Varani; Fiscal Year: 2001
    ..abstract_text> ..
  5. TOPICAL RETINOIDS FOR DIABETIC FOOT ULCERS
    James Varani; Fiscal Year: 2003
    ..abstract_text> ..
  6. ENDOTOXIN INDUCED MUCOUS CELL METAPLASIA
    Yohannes Tesfaigzi; Fiscal Year: 2003
    ..abstract_text> ..
  7. Mechanisms of MMP-3 Action in Acute Lung Injury
    James Varani; Fiscal Year: 2005
    ..These studies will provide an overall understanding of the mechanism(s) by which MMP-3 contributes to acute lung injury. ..
  8. Murine Cytomegalovirus Modulates Allergic Airway Disease
    Carol Wu; Fiscal Year: 2005
    ..Furthermore, we hypothesize that enhanced mucus production is the result of the recruitment/proliferation of TCRgd cells, in response to MCMV infected respiratory epithelium, with the subsequent release of IL-l0. ..
  9. Peroxynitrite decomposition catalyst:diabetic neuropathy
    IRINA OBROSOVA; Fiscal Year: 2006
    ..abstract_text> ..
  10. MICROCIRCULATION OF UVEAL MELANOMA
    Robert Folberg; Fiscal Year: 2007
    ..abstract_text> ..
  11. TEXAS REPOSITORY FOR AIDS NEUROPATHOGENESIS RESEARCH
    Benjamin Gelman; Fiscal Year: 2007
    ..abstract_text> ..
  12. MICROARRAY ANALYSIS OF RETINAL DEGENERATION IN MICE
    Caroline Zeiss; Fiscal Year: 2007
    ..Colin Barnstable, Professor of Neurobiology and Ophthalmology, who is an internationally recognized molecular biologist using mouse models of retinal development and degeneration. ..
  13. Dopamine Systems and Neuropsychiatric Changes in HIV/AIDS
    Benjamin B Gelman; Fiscal Year: 2010
    ..The project breaks ground neuroscientifically, as no autopsy study has advanced to a "task specific" behavioral correlation with circuit level anomalies of a specific neurotransmitter system. ..
  14. The stress of dry eye on corneal barrier function
    CINTIA DE PAIVA; Fiscal Year: 2006
    ..TJ and LEP expression will be evaluated by laser scanning confocal microscopy and immunostaining. Pro inflammatory mediator expression will be evaluated by Western Blot, ELISA and the Luminex Multiplex Assay. [unreadable] [unreadable]..
  15. Poly(ADP-ribose) polymerase in diabetic nephropathy
    IRINA OBROSOVA; Fiscal Year: 2006
    ..abstract_text> ..
  16. CONSEQUENCES OF MALE LH RECEPTOR GENE KNOCKOUT
    Zhenmin Lei; Fiscal Year: 2002
    ....
  17. Pathophysiology of Mucus Hypersecretion in Asthma
    Christopher Evans; Fiscal Year: 2003
    ..The project proposed here utilizes expertise and reagents available in his laboratory applies them to an important problem in asthma. ..
  18. MYELOPATHY AND NEUROPATHY DURING CHANGING HIV BURDEN
    Benjamin Gelman; Fiscal Year: 2004
    ..Together, the studies we have proposed will provide insights concerning prevalent AIDS morbidities in the HAART era. ..
  19. HIV and the Proteasome in the Aging Human Brain
    Benjamin Gelman; Fiscal Year: 2005
    ..The linkage between brain inflammation and altered neuronal protein turnover could lead to a unifying functional concept of dementia with application to HIV and aging both. ..
  20. Ultrasound Monitoring of Rat Metastatic Uveal Melanoma
    RODNEY BRAUN; Fiscal Year: 2007
    ..primary choroidal melanoma, [unreadable] differences in tumor progression can be correlated to the presence of periodic acid-Schiff base (PAS)-positive loops in the primary tumor...
  21. Occult Hepatitis B
    Michael Torbenson; Fiscal Year: 2007
    ..abstract_text> ..
  22. Chronic Alcohol Consumption Induces Tumor Angiogenesis
    Jian Wei Gu; Fiscal Year: 2006
    ..The new information will promote cancer prevention and treatment. ..
  23. ROLES OF NITRIC OXIDE AND OXYGEN IN OCULAR MELANOMA
    RODNEY BRAUN; Fiscal Year: 2002
    ....
  24. Applicability of mAbs in diagnosis of esophageal cancers
    ROUDABEH JAMASBI; Fiscal Year: 2002
    ..Phage display technique will also be attempted as an alternative and/or additional method to generate diagnostic/therapeutic reagents. ..