palladium

Summary

Summary: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.

Top Publications

  1. ncbi A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling
    Justin M Chalker
    Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK
    J Am Chem Soc 131:16346-7. 2009
  2. pmc Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination
    Dong Hui Wang
    Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 327:315-9. 2010
  3. pmc Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals
    J T Minang
    Department of Immunology, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 146:417-26. 2006
  4. ncbi Growth of semiconducting graphene on palladium
    Soon Yong Kwon
    Department of Materials Science and Engineering, University of California Los Angeles, Los Angeles, California 90095, USA
    Nano Lett 9:3985-90. 2009
  5. pmc Weak coordination as a powerful means for developing broadly useful C-H functionalization reactions
    Keary M Engle
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Acc Chem Res 45:788-802. 2012
  6. ncbi Antiproliferative effect of novel platinum(II) and palladium(II) complexes on hepatic tumor stem cells in vitro
    Natalia Miklásová
    Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia
    Eur J Med Chem 49:41-7. 2012
  7. ncbi Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature
    Xin Mu
    State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
    J Am Chem Soc 134:878-81. 2012
  8. ncbi Freestanding palladium nanosheets with plasmonic and catalytic properties
    Xiaoqing Huang
    State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
    Nat Nanotechnol 6:28-32. 2011
  9. ncbi Palladium-mediated cell-surface labeling
    Christopher D Spicer
    Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK
    J Am Chem Soc 134:800-3. 2012
  10. ncbi Cytogenetic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds
    Lucia Migliore
    Dipartimento di Scienze dell Uomo e dell Ambiente, University of Pisa, Via S Giuseppe 22, 56126 Pisa, Italy
    Mutagenesis 17:411-7. 2002

Detail Information

Publications424 found, 100 shown here

  1. ncbi A convenient catalyst for aqueous and protein Suzuki-Miyaura cross-coupling
    Justin M Chalker
    Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK
    J Am Chem Soc 131:16346-7. 2009
    A phosphine-free palladium catalyst for aqueous Suzuki-Miyaura cross-coupling is presented. The catalyst is active enough to mediate hindered, ortho-substituted biaryl couplings but mild enough for use on peptides and proteins...
  2. pmc Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination
    Dong Hui Wang
    Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 327:315-9. 2010
    ..We demonstrate the versatility of the method through direct elaboration of commercial drug scaffolds and efficient syntheses of 2-tetralone and naphthoic acid natural product cores...
  3. pmc Nickel, cobalt, chromium, palladium and gold induce a mixed Th1- and Th2-type cytokine response in vitro in subjects with contact allergy to the respective metals
    J T Minang
    Department of Immunology, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 146:417-26. 2006
    ..allergy has been limited, we investigated the cytokine profile induced by Ni, cobalt (Co), chromium (Cr), palladium (Pd) and gold (Au) in PBMC from patients with patch test reactivity to the respective metals...
  4. ncbi Growth of semiconducting graphene on palladium
    Soon Yong Kwon
    Department of Materials Science and Engineering, University of California Los Angeles, Los Angeles, California 90095, USA
    Nano Lett 9:3985-90. 2009
    ..Our findings point to the possibility of preparing semiconducting graphene layers for future carbon-based nanoelectronic devices via direct deposition onto strongly interacting substrates...
  5. pmc Weak coordination as a powerful means for developing broadly useful C-H functionalization reactions
    Keary M Engle
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Acc Chem Res 45:788-802. 2012
    ....
  6. ncbi Antiproliferative effect of novel platinum(II) and palladium(II) complexes on hepatic tumor stem cells in vitro
    Natalia Miklásová
    Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia
    Eur J Med Chem 49:41-7. 2012
    Novel platinum and palladium complexes with (2-isopropoxyphenyl)dicyclohexylarsine and (2-methoxyphenyl)dicyclohexylarsine ligands were synthesized and tested on different tumor cells...
  7. ncbi Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature
    Xin Mu
    State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
    J Am Chem Soc 134:878-81. 2012
    A palladium-catalyzed intramolecular oxidative aryltrifluoromethylation reaction of activated alkenes has been explored. The reaction allows for an efficient synthesis of a variety of CF(3)-containing oxindoles...
  8. ncbi Freestanding palladium nanosheets with plasmonic and catalytic properties
    Xiaoqing Huang
    State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
    Nat Nanotechnol 6:28-32. 2011
    ..Here we report the facile synthesis of freestanding hexagonal palladium nanosheets that are less than 10 atomic layers thick, using carbon monoxide as a surface confining agent...
  9. ncbi Palladium-mediated cell-surface labeling
    Christopher D Spicer
    Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK
    J Am Chem Soc 134:800-3. 2012
    ....
  10. ncbi Cytogenetic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds
    Lucia Migliore
    Dipartimento di Scienze dell Uomo e dell Ambiente, University of Pisa, Via S Giuseppe 22, 56126 Pisa, Italy
    Mutagenesis 17:411-7. 2002
    This study of soluble compounds of platinum, palladium and rhodium investigated the genotoxic properties of (NH(4))(2)PtCl(4), PtCl(2), PtCl(4), (NH(4))(2)PdCl(4), PdCl(2) and RhCl(3) using the human lymphocyte micronucleus (MN) assay ..
  11. pmc Pd(II)-catalyzed olefination of electron-deficient arenes using 2,6-dialkylpyridine ligands
    Yang Hui Zhang
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    J Am Chem Soc 131:5072-4. 2009
    ..The combination of directed and nondirected C-H functionalization of arenes provides a versatile route for the synthesis of highly sought after 1,2,4-trisubstituted arenes...
  12. pmc A fluoride-derived electrophilic late-stage fluorination reagent for PET imaging
    Eunsung Lee
    Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA
    Science 334:639-42. 2011
    ..We report the development of a palladium-based electrophilic fluorination reagent derived from fluoride and its application to the synthesis of aromatic (..
  13. ncbi A reaction-based fluorescent probe for selective imaging of carbon monoxide in living cells using a palladium-mediated carbonylation
    Brian W Michel
    Department of Chemistry, University of California, Berkeley, California 94720, United States
    J Am Chem Soc 134:15668-71. 2012
    ..Here we report a new type of turn-on fluorescent probe for selective CO detection based on palladium-mediated carbonylation reactivity...
  14. ncbi Rayleigh anomaly-surface plasmon polariton resonances in palladium and gold subwavelength hole arrays
    H Gao
    Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208, USA
    Opt Express 17:2334-40. 2009
    ..The apparent generality of the RA-SPP effect enables a novel route to optimize resonances in non-traditional plasmonic media...
  15. ncbi Palladium-mediated intracellular chemistry
    Rahimi M Yusop
    School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, UK
    Nat Chem 3:239-43. 2011
    ..Here, we show that palladium nanoparticles trapped within polystyrene microspheres can enter cells and mediate a variety of Pd(0)-catalysed ..
  16. ncbi Effects of palladium nanoparticles on the cytokine release from peripheral blood mononuclear cells of palladium-sensitized women
    Marcella Reale
    Department of Oncology and Experimental Medicine, G D Annunzio University, Chieti, Italy
    J Occup Environ Med 53:1054-60. 2011
    To investigate the effects of palladium (Pd) nanoparticles on cytokine release from peripheral blood mononuclear cells (PBMCs) of control or Pd-sensitized nonatopic women.
  17. ncbi Palladium-catalyzed oxidative carbocyclization/arylation of enallenes
    Tuo Jiang
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE 10691, Stockholm, Sweden
    Org Lett 13:5838-41. 2011
    A stereoselective palladium-catalyzed oxidative carbocyclization/arylation of enallenes is described...
  18. ncbi Palladium-catalyzed oxidative diarylating carbocyclization of enynes
    Min Jiang
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE 106 91 Stockholm, Sweden
    Org Lett 14:3538-41. 2012
    A mild and efficient palladium-catalyzed oxidative diarylating carbocyclization of enynes is described. The reaction tolerates a range of functionalized arylboronic acids to give diarylated products in good yields...
  19. ncbi Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis
    Debora P Santana
    Centro Interdisciplinar de Investigação Bioquímica CIIB, Universidade de Mogi das Cruzes UMC, Av Dr Cândido Xavier de Almeida e Souza, 200 Mogi das Cruzes, Sao Paulo, Brazil
    Biochem J 417:247-56. 2009
    ..Besides the contribution to clarify the pro-apoptotic mechanism of PdC, this study shows that the catalysis of specific protein thiol cross-linkage is enough to induce mitochondrial permeabilization and cytochrome c release...
  20. ncbi Highly regioselective arylation of sp3 C-H bonds catalyzed by palladium acetate
    Vladimir G Zaitsev
    Department of Chemistry, University of Houston, Houston, Texas 77204 5003, USA
    J Am Chem Soc 127:13154-5. 2005
    A new palladium-catalyzed arylation process based on C-H activation has been developed...
  21. ncbi Recent advances involving palladium (II) complexes for the cancer therapy
    Antonio Carlos Favero Caires
    Centro Interdisciplinar de Investigação Bioquímica CIIB, Universidade de Mogi das Cruzes, Av Cândido Xavier de Almeida Souza, 200 CEP 08701 970, CP 411, Mogi das Cruzes SP, Brazil
    Anticancer Agents Med Chem 7:484-91. 2007
    ..deals with the most important results published on the structures, reactivity and biomedical applications of palladium(II) complexes in the cancer therapy in the last five years...
  22. ncbi Sensitization to palladium chloride: a 10-year evaluation
    Francesca Larese Filon
    Istituto di Medicina del Lavoro, Universita degli Studi di Trieste, Italy
    Am J Contact Dermat 14:78-81. 2003
    b>Palladium is increasingly used in industry, jewelry, and dentistry and is becoming more common since the European directive restricting the use of nickel in all products placed in direct and prolonged contact with the skin.
  23. ncbi Palladium alloys for biomedical devices
    John C Wataha
    University of Washington School of Dentistry, Seattle, WA, USA
    Expert Rev Med Devices 7:489-501. 2010
    In the biomedical field, palladium has primarily been used as a component of alloys for dental prostheses...
  24. ncbi Effects of palladium nanoparticles on the cytokine release from peripheral blood mononuclear cells of non-atopic women
    Paolo Boscolo
    Operative Unit of Occupational Medicine of the University G d Annunzio of Chieti Pescara, Chieti, Pescara, Italy
    J Biol Regul Homeost Agents 24:207-14. 2010
    ..This result is interesting considering the increase of allergic contact dermatitis to Pd in people exposed to Pd nanoparticles in urban environments...
  25. ncbi Adsorption of platinum (IV), palladium (II) and gold (III) from aqueous solutions onto L-lysine modified crosslinked chitosan resin
    Kensuke Fujiwara
    Department of Chemistry and Chemical Engineering, Graduate School of Natural Science and Technology, Kakuma, Kanazawa University, Kanazawa 920 1192, Japan
    J Hazard Mater 146:39-50. 2007
    ..The desorption studies were carried out using various reagents. The maximum percent desorption of precious metal ions were obtained when the reagent 0.7 M thiourea-2 M HCl was used...
  26. pmc Palladium nanoparticles deposited on silanized halloysite nanotubes: synthesis, characterization and enhanced catalytic property
    Yi Zhang
    Department of Inorganic Materials, School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China
    Sci Rep 3:2948. 2013
    b>Palladium (Pd) nanoparticles were deposited on the surface of halloysite nanotubes (HNTs) modified with γ-aminopropyltriethoxysilane (APTES) to produce Pd/NH2-HNTs nanocomposites...
  27. ncbi Formal synthesis of nitidine and NK109 via palladium-catalyzed domino direct arylation/N-arylation of aryl triflates
    Mathieu Blanchot
    Davenport Research Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada, M5S 3H6
    Org Lett 13:1486-9. 2011
    The use of aryl triflates as reaction partners in a palladium-catalyzed domino direct arylation/N-arylation provides a great advantage due to the availability of starting materials...
  28. ncbi Nature of molecular interactions of peptides with gold, palladium, and Pd-Au bimetal surfaces in aqueous solution
    Hendrik Heinz
    Department of Polymer Engineering, University of Akron, Akron, Ohio 44325, USA
    J Am Chem Soc 131:9704-14. 2009
    ..Vaia, R. A.; Farmer, B. L.; Naik, R. R. J. Phys. Chem. C 2008, 112, 17281-17290]...
  29. ncbi Release of palladium from biomechanical prostheses in body fluids can induce or support PD-specific IFNgamma T cell responses and the clinical setting of a palladium hypersensitivity
    A Cristaudo
    Department of Allergy, San Gallicano Dermatology Institute, Rome, Italy
    Int J Immunopathol Pharmacol 22:605-14. 2009
    The increased use of Palladium (Pd) for biomedical applications, which has more than doubled in the last ten years, appears to be associated with an increased frequency of adverse reactions to Pd...
  30. ncbi Palladium complexes affect the aggregation of human prion protein PrP106-126
    Yanli Wang
    Department of Chemistry, Renmin University of China, Beijing 100872, China
    Inorg Chem 50:4340-8. 2011
    ..This finding would prove valuable in helping design and develop novel metallodrugs against prion diseases...
  31. ncbi Captured and cross-linked palladium nanoparticles
    Jin Ku Cho
    School of Chemistry, Joshep Black Building, King s Buildings, The University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, United Kingdom
    J Am Chem Soc 128:6276-7. 2006
    Polystyrene-poly(ethylene glycol) resin-captured cross-linked palladium nanopaticles were prepared via a straightforward route, and their heterogeneous behavior was truly confirmed by various tests...
  32. pmc A highly selective and general palladium catalyst for the oxidative Heck reaction of electronically nonbiased olefins
    Erik W Werner
    Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112, USA
    J Am Chem Soc 132:13981-3. 2010
    ..A preliminary mechanistic investigation suggests that the unusually high selectivity may be due to the catalyst's sensitivity to C-H bond strength in the selectivity-determining β-hydride elimination step...
  33. ncbi Biologic activity of a dinuclear Pd(II)-spermine complex toward human breast cancer
    Sonia M Fiuza
    Química Física Molecular, Departamento de Quimica, FCTUC, Universidade de Coimbra, Portugal
    Chem Biol Drug Des 77:477-88. 2011
    A dinuclear palladium-based complex (Pd(2) -Spm) was synthesized and compared with cisplatin (cDDP) on two different human breast cancer cell lines (MCF-7 and MDA-MB-231) as well as toward an untransformed cell line (BJ fibroblasts)...
  34. ncbi Palladium-catalyzed carboiodination of alkenes: carbon-carbon bond formation with retention of reactive functionality
    Stephen G Newman
    Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6
    J Am Chem Soc 133:1778-80. 2011
    We report a palladium-catalyzed carbon-carbon bond-forming reaction between aryl iodides and alkenes...
  35. pmc Distinguishing between pathways for transmetalation in Suzuki-Miyaura reactions
    Brad P Carrow
    Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, United States
    J Am Chem Soc 133:2116-9. 2011
    ..On the basis of the relative populations of the palladium and organoboron species generated under conditions common for the catalytic process and the observed rate ..
  36. ncbi Metal allergen of the 21st century--a review on exposure, epidemiology and clinical manifestations of palladium allergy
    Annesofie Faurschou
    Department of Dermato Allergology, National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, Hellerup, Denmark
    Contact Dermatitis 64:185-95. 2011
    Consumers are mainly exposed to palladium from jewellery and dental restorations. Palladium contact allergy is nearly always seen together with nickel allergy, as palladium and nickel tend to cross-react...
  37. ncbi Palladium--a review of exposure and effects to human health
    Janet Kielhorn
    Fraunhofer Institute for Toxicology and Aerosol Research, Drug Research and Clinical Inhalation, Nikolai Fuchs Strasse 1, D 30625 Hannover, Germany
    Int J Hyg Environ Health 205:417-32. 2002
    b>Palladium is a metal the output and use of which has more than doubled in the past ten years...
  38. pmc Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions employing dialkylbiaryl phosphine ligands
    Ruben Martin
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Acc Chem Res 41:1461-73. 2008
    ..These ligands can be used for a wide variety of palladium-catalyzed carbon-carbon, carbon-nitrogen, and carbon-oxygen bond-forming processes as well as serving as ..
  39. pmc Novel Pt(II) and Pd(II) complexes with polyamine analogues: synthesis and vibrational analysis
    T M Silva
    Research Unit Molecular Physical Chemistry, University of Coimbra, Coimbra, Portugal
    J Inorg Biochem 108:1-7. 2012
    ....
  40. ncbi Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides
    Edward J Emmett
    Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK
    Org Biomol Chem 10:4007-14. 2012
    By using DABCO·(SO(2))(2), DABSO, as a solid bench-stable SO(2)-equivalent, the palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides has been achieved...
  41. ncbi High dose rate brachytherapy as prostate cancer monotherapy reduces toxicity compared to low dose rate palladium seeds
    Inga S Grills
    Department of Radiation, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    J Urol 171:1098-104. 2004
    We evaluated the potential for differing acute and chronic toxicities between 2 monotherapy methods of image guided conformal brachytherapy, high dose rate (HDR) brachytherapy alone and low dose rate (LDR) permanent palladium seeds.
  42. pmc Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes
    Masayuki Wasa
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    J Am Chem Soc 133:19598-601. 2011
    ..These results provide a new retrosynthetic disconnection for the construction of enantioenriched cis-substituted cyclopropanecarboxylic acids...
  43. ncbi Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin-palladium complex
    Francesco Palazzo
    Department of Chemistry and Technology of Drugs, Universita degli Studi di Perugia, Via del Liceo 1, 06123 Perugia, Italy
    Int J Pharm 440:273-82. 2013
    ..Ofloxacin (Ofx) was encapsulated as ofloxacin-palladium (Ofx-Pd) complex into poly DL-lactide (PLA) MP by spray-drying...
  44. pmc Synthesis of substituted isoquinolines utilizing palladium-catalyzed α-arylation of ketones
    Timothy J Donohoe
    Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, United Kingdom
    Proc Natl Acad Sci U S A 109:11605-8. 2012
    The utilization of sequential palladium-catalyzed α-arylation and cyclization reactions provides a general approach to an array of isoquinolines and their corresponding N-oxides...
  45. pmc Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents
    Keary M Engle
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
    J Am Chem Soc 133:18183-93. 2011
    ..This ligand scaffold has also been shown to improve catalysis using 1 atm O(2) as the sole reoxidant, which sheds light on the path forward in developing optimized ligands for aerobic C-H/arylboron cross-coupling...
  46. ncbi Preparation and characterization of amino-linked heterocyclic carbene palladium, gold, and silver complexes and their use as anticancer agents that act by triggering apoptotic cell death
    Chie Hong Wang
    Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan
    J Med Chem 54:5245-9. 2011
    ..The results indicate that 3 induces apoptosis through a p53-bak pathway, a finding that could serve as a new strategy to reduce the resistance of cancer cells to p53-induced apoptosis...
  47. ncbi Palladium-103 plaque radiotherapy for choroidal melanoma: an 11-year study
    Paul T Finger
    The New York Eye Cancer Center, St Vincent s Comprehensive Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 54:1438-45. 2002
    ..To describe 11 years of experience with 103Pd ophthalmic plaque brachytherapy for intraocular melanoma...
  48. pmc Microbial synthesis of core/shell gold/palladium nanoparticles for applications in green chemistry
    Kevin Deplanche
    Unit of Functional Bionanomaterials, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    J R Soc Interface 9:1705-12. 2012
    ..We report a novel biochemical method based on the sacrificial hydrogen strategy to synthesize bimetallic gold (Au)-palladium (Pd) nanoparticles (NPs) with a core/shell configuration...
  49. pmc Palladium-catalyzed, direct boronic acid synthesis from aryl chlorides: a simplified route to diverse boronate ester derivatives
    Gary A Molander
    Roy and Diana Vagelos Laboratories and Penn Merck Laboratory for High Throughput Experimentation, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6323, United States
    J Am Chem Soc 132:17701-3. 2010
    ..A simple and efficient palladium-catalyzed, direct synthesis of arylboronic acids from the corresponding aryl chlorides using an underutilized ..
  50. ncbi Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: indole synthesis from anilines and ketones
    Ye Wei
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore
    J Am Chem Soc 134:9098-101. 2012
    We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant...
  51. ncbi Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo
    Engin Ulukaya
    Uludag University, Medical School, Department of Medical Biochemistry, Bursa, Turkey
    Eur J Med Chem 46:4957-63. 2011
    Anti-cancer effects of a newly-synthesized palladium(II) complex, [Pd(sac)(terpy)](sac)·4H(2)O (sac = saccharinate, and terpy = 2,2':6',2''-terpyridine), were tested against human breast cancer cell lines, MCF-7 and MDA-MB-231...
  52. ncbi A glucose biosensor based on electrodeposition of palladium nanoparticles and glucose oxidase onto Nafion-solubilized carbon nanotube electrode
    San Hua Lim
    Department of Physics, National University of Singapore, Singapore 119260, Singapore
    Biosens Bioelectron 20:2341-6. 2005
    Electrodeposition was used for the co-deposition of glucose oxidase (GOx) enzymes and palladium nanoparticles onto a Nafion-solubilized carbon nanotube (CNT) film...
  53. ncbi A permanent breast seed implant as partial breast radiation therapy for early-stage patients: a comparison of palladium-103 and iodine-125 isotopes based on radiation safety considerations
    Brian Keller
    Department of Medical Physics, Sunnybrook and Women s Health Sciences Centre, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 62:358-65. 2005
    ..This study compares iodine-125 ((125)I) and palladium-103 ((103)Pd) isotopes by examining the exposure and effective dose (ED) to a patient's partner.
  54. ncbi Synthesis of polysubstituted imidazo[1,2-a]pyridines via microwave-assisted one-pot cyclization/Suzuki coupling/palladium-catalyzed heteroarylation
    Jamal Koubachi
    Institut de Chimie Organique et Analytique, UMR CNRS 6005, Universite d Orleans, BP 6759, 45067 Orleans Cedex 2, France
    J Org Chem 72:7650-5. 2007
    ..Polysubstituted compounds are obtained in good yield from 2-amino-5-halogenopyridines, 2-halogenocarbonyl derivatives, boronic acids, and heteroaryl bromides...
  55. ncbi A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains
    Johan Wannberg
    Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala University, BMC, Box 574, SE 751 23 Uppsala, Sweden
    Bioorg Med Chem 14:5303-15. 2006
    ..containing C-terminal duplicated inhibitors served as starting materials for microwave-enhanced palladium(0)-catalyzed carbon-carbon bond forming reactions (Suzuki, Sonogashira, Heck, and Negishi)...
  56. ncbi Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)]
    Rodrigo A de Souza
    Sao Paulo State Univ, Instituto de Quimica de Araraquara, Rua Prof Francisco Degni s n, C P 355, 14800 900 Araraquara, SP, Brazil
    Eur J Med Chem 45:4863-8. 2010
    ..Among the complexes, compound 2 was found to be the most active with MIC of 35.89 μM. Complexes 1-4 were also screened for their in vitro antitumor activity towards LM3 and LP07 murine cancer cell lines...
  57. ncbi Tolerance and acceptance results of a palladium-103 permanent breast seed implant Phase I/II study
    Jean Philippe Pignol
    Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 73:1482-8. 2009
    ..To test, in a prospective Phase I/II trial, a partial breast irradiation technique using a 103Pd permanent breast seed implant (PBSI) realized in a single 1-h procedure under sedation and local freezing...
  58. ncbi Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands
    Radim Vrzal
    Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Olomouc, Czech Republic
    J Inorg Biochem 104:1130-2. 2010
    ..2+/-3.8 microM for 12) and A2780 (IC(50)=5.4+/-1.2 microM for 14) was evaluated for the palladium(II) oxalato complexes, which again exceeded cisplatin, whose IC(50) equalled 19.6+/-4...
  59. pmc Mechanism of Escherichia coli inactivation on palladium-modified nitrogen-doped titanium dioxide
    Pinggui Wu
    Department of Materials Science and Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Biomaterials 31:7526-33. 2010
    ....
  60. pmc Palladium- and copper-catalyzed arylation of carbon-hydrogen bonds
    OLAFS DAUGULIS
    Department of Chemistry, University of Houston, Houston, Texas 77204 5003, USA
    Acc Chem Res 42:1074-86. 2009
    ..Finally, the palladium, rhodium, and ruthenium catalysts routinely used for the conversion of C-H bonds to C-C bonds are expensive...
  61. ncbi Determination of the structure of an endoglucanase from Aspergillus niger and its mode of inhibition by palladium chloride
    Shahram Khademi
    Biographics Laboratory, Texas A and M University, Department of Biochemistry and Biophysics, College Station, TX 77843 2128, USA
    Acta Crystallogr D Biol Crystallogr 58:660-7. 2002
    ..Incubation of EglA with PdCl(2) irreversibly inhibits the EglA activity. Structural studies of the enzyme-palladium complex show that three Pd(2+) ions bind to each EglA molecule...
  62. pmc Oxidative palladium(II) catalysis: A highly efficient and chemoselective cross-coupling method for carbon-carbon bond formation under base-free and nitrogenous-ligand conditions
    Kyung Soo Yoo
    Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089 1661, USA
    J Am Chem Soc 128:16384-93. 2006
    ..For instance, oxidative palladium(II) catalysis is effective with highly substituted alkenes and cyclic alkenes, which are known to be ..
  63. ncbi Adsorption of gold(III), platinum(IV) and palladium(II) onto glycine modified crosslinked chitosan resin
    A Ramesh
    Department of Chemistry and Chemical Engineering, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa 920 1192, Japan
    Bioresour Technol 99:3801-9. 2008
    ..The modification of glycine on crosslinked chitosan resin (CCR) was studied by Fourier transform infrared spectrometry (FTIR) and scanning electron microscopy (SEM)...
  64. pmc The development of versatile methods for palladium-catalyzed coupling reactions of aryl electrophiles through the use of P(t-Bu)3 and PCy3 as ligands
    Gregory C Fu
    Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Acc Chem Res 41:1555-64. 2008
    ..In particular, we have established that palladium in combination with a bulky trialkylphosphine accomplishes a broad spectrum of coupling processes, including ..
  65. ncbi Palladium nanoparticles captured in microporous polymers: a tailor-made catalyst for heterogeneous carbon cross-coupling reactions
    Shin Ogasawara
    Kawamura Institute of Chemical Research, 631 Sakado, Sakura, Chiba 285 0078, Japan
    J Am Chem Soc 132:4608-13. 2010
    A new strategy based on polymerization-induced phase separation (PIPS) techniques was proposed for fabricating palladium nanoparticles (PdNPs) captured in a microporous network polymer...
  66. ncbi Palladium-catalyzed direct ethynylation of C(sp3)-H bonds in aliphatic carboxylic acid derivatives
    Yusuke Ano
    Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565 0871, Japan
    J Am Chem Soc 133:12984-6. 2011
    ..The method allows for the straightforward introduction of an ethynyl group into aliphatic acid derivatives under palladium catalysis...
  67. ncbi Simple synthesis of palladium nanoparticles, β-phase formation, and the control of chain and dipole orientations in palladium-doped poly(vinylidene fluoride) thin films
    Dipankar Mandal
    Department of Advanced Materials Engineering for Information and Electronics, College of Engineering, Kyung Hee University, Yongin si, Gyeonggi Do 446 701, South Korea
    Langmuir 28:10310-7. 2012
    b>Palladium nanoparticles (Pd-NP's) are prepared by a simple one-step procedure when poly(vinylidene fluoride) (PVDF) is used as a polymer stabilizer...
  68. pmc Direct palladium(II)-catalyzed synthesis of arylamidines from aryltrifluoroborates
    Jonas Sävmarker
    Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry BMC, Uppsala University, Box 574, SE 751 23, Uppsala, Sweden
    Org Lett 14:2394-7. 2012
    ..The coupling was achieved by Pd(II)-catalysis in a one step 20 min microwave protocol using Pd(O(2)CCF(3)), 6-methyl-2,2'-bipyridyl, TFA, and MeOH, providing the corresponding arylamidines in moderate to excellent yields...
  69. ncbi Platinum(II) and palladium(II) complexes with (N,N') and (C,N,N')- ligands derived from pyrazole as anticancer and antimalarial agents: synthesis, characterization and in vitro activities
    Josefina Quirante
    Laboratori de Química Orgànica, Facultat de Farmacia, Institut de Biomedicina, IBUB, Universitat de Barcelona, Barcelona, Spain
    J Inorg Biochem 105:1720-8. 2011
    ..Electrophoretic DNA migration studies in presence of the synthesized compounds have been performed, in order to get further insights into their mechanism of action...
  70. pmc Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells
    Ramakumar Tummala
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Oncol Rep 24:15-24. 2010
    ..These studies suggest that Pd (II)-polyamine complexes may constitute a promising group of inorganic compounds for further studies in the development of novel chemotherapy/adjuvant chemotherapy strategies...
  71. pmc Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst
    Masayuki Wasa
    Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States
    J Am Chem Soc 134:18570-2. 2012
    ..Ligand tuning led to the development of a method that allows for installation of an aryl group on a range of acyclic and cyclic amides containing β-methylene C(sp(3))-H bonds...
  72. ncbi Palladium-catalyzed diastereo- and enantioselective Wagner-Meerwein shift: control of absolute stereochemistry in the C-C bond migration event
    Barry M Trost
    Department of Chemistry, Stanford University, Stanford, California 94305, USA
    J Am Chem Soc 130:6231-42. 2008
    ..The method provides an efficient way to synthesize highly substituted cyclopentanones with an alpha-chiral O-tertiary center which has various synthetic applications...
  73. ncbi Palladium-catalyzed decarboxylative coupling of alkynyl carboxylic acids with benzyl halides or aryl halides
    Wen wu Zhang
    College of Chemistry and Materials Science, Wenzhou University, Wenzhou 325035, China
    J Org Chem 75:5259-64. 2010
    The synthesis of internal benzyl alkynes and 1,2-diarylalkynes has been developed via palladium-catalyzed decarboxylative coupling reactions of alkynyl carboxylic acids with benzyl chlorides or aryl halides...
  74. ncbi Adsorption of platinum(IV) and palladium(II) from aqueous solution by magnetic cross-linking chitosan nanoparticles modified with ethylenediamine
    Limin Zhou
    Key Laboratory of Nuclear Resources and Environment Ministry of Education, East China Institute of Technology, Fuzhou, Jiangxi 344000, PR China
    J Hazard Mater 182:518-24. 2010
    The adsorption characteristics of platinum(IV) and palladium(II) from aqueous solutions onto the ethylenediamine-modified magnetic chitosan nanoparticles (EMCN) have been investigated...
  75. ncbi Palladium-103 ophthalmic plaque radiation therapy for choroidal melanoma: 400 treated patients
    Paul T Finger
    The New York Eye Cancer Center, New York, New York 10065, USA
    Ophthalmology 116:790-6, 796.e1. 2009
    To describe 18 years of experience with palladium-103 ((103)Pd) ophthalmic plaque brachytherapy.
  76. ncbi Passive fit of frameworks in titanium and palladium-silver alloy submitted the laser welding
    S A de Sousa
    Piracicaba Dentistry School, Campinas State University, Piracicaba, Sao Paulo, Brazil
    J Oral Rehabil 35:123-7. 2008
    This study evaluated the precision of fit of implant frameworks cast in titanium (cp Ti) and palladium-silver alloy (Pd-Ag), made by the one-piece cast and laser welding techniques...
  77. ncbi On the thermal stability of surface-assembled viral-metal nanoparticle complexes
    Amy K Manocchi
    Department of Chemical and Biological Engineering, Tufts University, 4 Colby Street, Medford, Massachusetts 02155, USA
    Langmuir 26:7516-22. 2010
    ..to examine the thermal stability of viral-nanoparticle complexes composed of tobacco mosaic virus (TMV) and palladium nanoparticles...
  78. pmc Palladium(II)-catalyzed cyclization of unsaturated hydroperoxides for the synthesis of 1,2-dioxanes
    Jason R Harris
    Department of Chemistry, University of California, Irvine, California 92697 2025, USA
    Org Lett 11:3290-3. 2009
    The cyclization of gamma,delta-unsaturated tertiary hydroperoxides in the presence of a palladium(II) catalyst afforded 1,2-dioxanes resembling biologically active natural products...
  79. ncbi Palladium(II) and platinum(II) organometallic complexes with 4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine. Antitumor activity of the platinum compounds
    Jose Ruiz
    Departamento de Quimica Inorganica, Universidad de Murcia, E 30071 Murcia, Spain
    Inorg Chem 47:4490-505. 2008
    b>Palladium and platinum complexes with HmtpO (where HmtpO=4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine, an analogue of the natural occurring nucleobase hypoxanthine) of the types [M(dmba)(PPh3)(HmtpO)]ClO4[dmba=N,C-chelating ..
  80. ncbi Oxidative addition of the fluoromethane C-F bond to Pd. An ab initio benchmark and DFT validation study
    G Theodoor de Jong
    Afdeling Theoretische Chemie, Scheikundig Laboratorium der Vrije Universiteit, De Boelelaan 1083, NL 1081 HV Amsterdam, The Netherlands
    J Phys Chem A 109:9685-99. 2005
    ..pathways (oxidative insertion, OxIn, and S(N)2) for oxidative addition of the fluoromethane C-F bond to the palladium atom and have used this to evaluate the performance of 26 popular density functionals, covering LDA, GGA, meta-..
  81. ncbi Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells
    Alessandra Valentini
    Department of Laboratory Medicine, UOC Clinical Molecular Biology, PTV Hospital University Tor Vergata, Via Oxford 81, 00133 Rome, Italy
    J Med Chem 52:484-91. 2009
    ....
  82. ncbi Palladium-catalyzed regioselective arylation of imidazo[1,2-b][1,2,4]triazine: synthesis of an alpha 2/3-selective GABA agonist
    Donald R Gauthier
    Department of Process Research, Merck Research Laboratories, Merck and Co Inc, P O Box 2000, Rahway, NJ 07065, USA
    J Org Chem 70:5938-45. 2005
    ..A highly regioselective palladium-catalyzed arylation in the final step highlights the efficiency of the route.
  83. ncbi Defect-free <110> zinc-blende structured InAs nanowires catalyzed by palladium
    Hongyi Xu
    Materials Engineering, The University of Queensland, QLD 4072, Australia
    Nano Lett 12:5744-9. 2012
    ..the epitaxial growth of defect-free zinc-blende structured InAs nanowires on GaAs{111}(B) substrates using palladium catalysts in a metal-organic chemical vapor deposition reactor...
  84. ncbi Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode
    Jianshe Huang
    State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, Jilin 130022, PR China
    Biosens Bioelectron 24:632-7. 2008
    b>Palladium nanoparticle-loaded carbon nanofibers (Pd/CNFs) were prepared by electrospinning and subsequent thermal treatment processes...
  85. ncbi Catalytic hydrogenation of polyaromatic hydrocarbon (PAH) compounds in supercritical carbon dioxide over supported palladium
    Tao Yuan
    Department of Food Science and Agricultural Chemistry, Macdonald Campus of McGill University, 21, 111 Lakeshore Road, Ste Anne de Bellevue, QC, CanadaH9X 3V9
    J Environ Monit 9:1344-51. 2007
    A series of supported palladium catalysts were evaluated for their ability to mediate the complete hydrogenation of polycyclic aromatic hydrocarbon (PAH) compounds...
  86. ncbi Accurate modelling of Pd(0) + PhX oxidative addition kinetics
    Claire L McMullin
    School of Chemistry, University of Bristol, Cantock s Close, Bristol, UK BS8 1TS
    Dalton Trans 39:10833-6. 2010
    ..Barrios-Landeros, B. P. Carrow and J. F. Hartwig, J. Am. Chem. Soc., 2009, 131, 8141-8154). The calculated activation free energies agree near-quantitatively with experimentally observed rate constants...
  87. ncbi Stereoselective beta-hydroxy-alpha-amino acid synthesis via an ether-directed, palladium-catalysed aza-Claisen rearrangement
    Kate N Fanning
    WestCHEM, Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow, UKG12 8QQ
    Org Biomol Chem 3:3749-56. 2005
    ..acids has been developed from enantiopure alpha-hydroxy acids using a MOM-ether-directed, palladium(II)-catalysed, aza-Claisen rearrangement of allylic acetimidates to effect the key step...
  88. ncbi Palladium(0)-catalyzed cross-coupling of potassium (Z)-2-chloroalk-1-enyl trifluoroborates: a chemo- and stereoselective access to (Z)-chloroolefins and trisubstituted alkenes
    Xavier Guinchard
    CNRS Institut de Chimie des Substances Naturelles, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Chemistry 15:5793-8. 2009
    ..The usefulness of this methodology has been successfully illustrated by the first total synthesis of an N-acyl spermidine...
  89. pmc Synthesis of cyclic enones via direct palladium-catalyzed aerobic dehydrogenation of ketones
    Tianning Diao
    Department of Chemistry, University of Wisconsin Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA
    J Am Chem Soc 133:14566-9. 2011
    ..The substrate scope includes heterocyclic ketones and several natural-product precursors...
  90. doi Site-selective sp2 and benzylic sp3 palladium-catalyzed direct arylation
    Louis Charles Campeau
    Center for Catalysis Research and Innovation, University of Ottawa, Department of Chemistry, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5
    J Am Chem Soc 130:3266-7. 2008
  91. ncbi Solution-engineered palladium nanoparticles: model for health effect studies of automotive particulate pollution
    Kai E Wilkinson
    Department of Chemistry, Biocenter, Swedish University of Agricultural Sciences SLU, Box 7015, SE 75007, Uppsala, Sweden
    ACS Nano 5:5312-24. 2011
    b>Palladium (Pd) nanoparticles are recognized as components of airborne automotive pollution produced by abrasion of catalyst materials in the car exhaust system...
  92. ncbi Synthesis of tetrasubstituted alkenes through a palladium-catalyzed domino carbopalladation/C-H-activation reaction
    Lutz F Tietze
    Institut fur Organische und Biomolekulare Chemie, Georg August Universitat Gottingen, Tammannstrasse 2, 37077 Gottingen, Germany
    Chemistry 18:3286-91. 2012
    Helical tetrasubstituted alkenes (7) were obtained in a highly efficient way through a palladium-catalyzed domino-carbopalladation/CH-activation reaction of propargylic alcohols 6 in good to excellent yields...
  93. ncbi In situ small-angle X-ray scattering analysis of palladium nanoparticle growth on tobacco mosaic virus nanotemplates
    Amy K Manocchi
    Department of Chemical and Biological Engineering, Tufts University, 4 Colby Street, Medford Massachusetts 02155, United States
    Langmuir 27:7052-8. 2011
    We present an examination of palladium (Pd) nanoparticle growth on genetically modified tobacco mosaic virus (TMV1cys) nanotemplates via in situ small-angle X-ray scattering (SAXS)...
  94. ncbi Destruction of pentachlorobiphenyl in soil by supercritical CO(2) extraction coupled with polymer-stabilized palladium nanoparticles
    Joanna Shaofen Wang
    Department of Chemistry, University of Idaho, Moscow, 83844, USA
    Chemosphere 75:629-33. 2009
    ..the feasibility of coupling of supercritical fluid carbon dioxide (ScCO(2)) extraction with polymer-stabilized palladium nanoparticles for the destruction of pentachlorinated biphenyl (2,2',4,5,5'-PCB) from contaminated sand or soil ..
  95. ncbi Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes
    Hizbullah Khan
    Department of Chemistry, McGill University, Montreal, QC, Canada H3A 2K6
    Eur J Med Chem 46:4071-7. 2011
    ..These Pd(II) complexes also show moderate antibacterial activity against gram positive and gram negative bacteria...
  96. ncbi Differential toxic effect of cis-platinum(II) and palladium(II) chlorides complexed with methyl 3,4-diamine-2,3,4,6-tetradeoxy-alpha-L-lyxo-hexopyranoside in mouse lymphoma cell lines differing in DSB and NER repair ability
    Marcin Kruszewski
    Institute of Nuclear Chemistry and Technology, Warsaw, Poland
    Teratog Carcinog Mutagen . 2003
    The aim of this work was to test the cytotoxicity of newly synthesized cis-type complexes of platinum(II) and palladium(II) dichloride with methyl 3,4-diamine-2,3,4,6-tetradeoxy-alpha-L-lyxohexopyranoside, [M(C(7)H(16)N(2)O(2))Cl(2)]...
  97. ncbi Establishment of broadly applicable reaction conditions for the palladium-catalyzed direct arylation of heteroatom-containing aromatic compounds
    Benoît Liégault
    Center for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada
    J Org Chem 74:1826-34. 2009
    Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with aryl bromides are reported...
  98. pmc Effects of high-humidity aging on platinum, palladium, and gold loaded tin oxide--volatile organic compound sensors
    Toshio Itoh
    National Institute of Advanced Industrial Science and Technology, Shimo shidami, Moriyama ku, Nagoya 463 8560, Japan
    Sensors (Basel) 10:6513-21. 2010
    ..high-humidity aging effects on the total volatile organic compound (T-VOC) gas-sensing properties of platinum, palladium, and gold-loaded tin oxide (Pt,Pd,Au/SnO(2)) thick films...
  99. pmc Phosphorescent platinum(II) and palladium(II) complexes with azatetrabenzoporphyrins-new red laser diode-compatible indicators for optical oxygen sensing
    Sergey M Borisov
    Institute of Analytical Chemistry and Food Chemistry, Graz University of Technology, Stremayrgasse 16, 8010 Graz, Austria
    ACS Appl Mater Interfaces 2:366-74. 2010
    A new class of oxygen indicators is described. Platinum(II) and palladium(II) complexes of azatetrabenzoporphyrins occupy an intermediate position between tetrabenzoporphyrins and phthalocyanines and combine features of both...
  100. ncbi Total synthesis of (+/-)-rhazinal using novel palladium-catalyzed cyclizations
    Alfred L Bowie
    Department of Chemistry, University of California, Berkeley, California 94720, USA
    J Org Chem 74:1581-6. 2009
    A concise synthesis of (+/-)-rhazinal that hinges on novel oxidative Heck cyclizations and palladium-catalyzed direct couplings is described...
  101. pmc Breaking the regioselectivity rule for acrylate insertion in the Mizoroki-Heck reaction
    Philipp Wucher
    Department of Chemistry, University of Konstanz, 78464 Konstanz, Germany
    Proc Natl Acad Sci U S A 108:8955-9. 2011
    ..state of 2,1-insertion via steric interactions, the regioselectivity of methyl acrylate insertion into palladium-methyl and phenyl bonds can be inverted entirely to yield the opposite "regioirregular" products in ..

Research Grants67

  1. Sorbents for Toxic-Metal Removal in Pharmaceutical Development and Manufacture
    GIRISH SRINIVAS; Fiscal Year: 2013
    ..Goals are to remove catalytic metals and especially palladium to <5ppmw for oral medications and <0.5ppmw for parenteral medications...
  2. Sorbents for Toxic-Metal Removal in Pharmaceutical Development and Manufacture
    GIRISH SRINIVAS; Fiscal Year: 2011
    ..is well established from the known neurotoxicity and cytotoxicity of the anti- cancer agents, cis-platinum, cis-palladium and their analogues, which bind strongly to DNA and block transcription of critical neural enzymes and also bind,..
  3. Synthesis of Medicinally Important Heterocycles
    RICHARD LAROCK; Fiscal Year: 2007
    ..Subsequent elaboration of the resulting halogen-containing hetero- and carbocycles via palladium-catalyzed processes provides highly, efficient methodology for the construction of pharmaceutically interesting ..
  4. Catalytic Aerobic Oxidations for Pharmaceutical Synthesis: Flow-Reaction Methods
    Shannon S Stahl; Fiscal Year: 2010
    ..Initial studies will focus on palladium-catalyzed methods for aerobic alcohol oxidation, which have been the focus of considerable synthetic and ..
  5. Shape Shifting Phosphines in Transition Metal Catalysis
    THOMAS JOHN MAIMONE; Fiscal Year: 2012
    ..b>Palladium is often the metal of choice for a variety of these reactions which are routinely carried out on scales ranging ..
  6. Anti-Tumorigenic Potential of Novel Digitoxin Analogues
    Anand K Iyer; Fiscal Year: 2013
    ..These analogues will be generated using a divergent de novo palladium-catalyzed carbohydrate synthesis methodology and tested using in vitro, ex vivo and in silico techniques...
  7. Transition Metal Catalysis and Metabolic Engineering using Artificial Metalloenzy
    Jared C Lewis; Fiscal Year: 2010
    ..Independent (R00) research will focus on directed evolution of artificial metalloenzymes for in vivo palladium catalysis of pharmaceutically important cross-coupling reactions with potential applications in organic ..
  8. Quantization of Ocular Oxygen using a Modified Fluorotron
    James P Dillon; Fiscal Year: 2010
    ..modified a Fluorotron Ocular Fluorometer such that it can now detect phosphorescence from an oxygen sensitive palladium porphyrin (eg. PdUp palladium uroporphyrin)...
  9. Transition Metal Catalysis and Metabolic Engineering using Artificial Metalloenzy
    Jared C Lewis; Fiscal Year: 2013
    ..Independent (R00) research will focus on directed evolution of artificial metalloenzymes for in vivo palladium catalysis of pharmaceutically important cross-coupling reactions with potential applications in organic ..
  10. Palladium-Catalyzed Aerobic Dehydrogenation of Carbon-Carbon Bonds
    Shannon S Stahl; Fiscal Year: 2013
    ....
  11. Role of Ventral Pallidum Projection to VTA in Reinstatement of Cocaine Seeking
    STEPHEN VINCENT MAHLER; Fiscal Year: 2013
    ..Here, I examine the role of projections from the ventral palladium (VP) to ventral tegmental area (VTA) in a rat self-administration/cue-induced reinstatement model of relapse...
  12. Mechanism and Development of Catalysts for the Synthesis of Amines, Ethers, and S
    John F Hartwig; Fiscal Year: 2013
    ..One portion of the proposed research will focus on the development of a new generation of palladium catalysts for the coupling of amines with aryl halides using data on the factors that control catalyst ..
  13. NOVEL PALLADIUM CATALYZED SYNTHESES OF INDOLE ALKALOIDS
    BJORN SODERBERG; Fiscal Year: 2001
    ..The key step in this methodology is a recently developed, palladium catalyzed, N-heteroannulation reaction of 2-nitrostyrenes employing carbon monoxide as the reducing agent...
  14. Investigations of New Pd"/Pd"-catalyzed aryl C-F and C-CF3 Coupling Reactions
    NICHOLAS DEWAYNE BALL; Fiscal Year: 2010
    ..This project's long-term objective is to develop more practical methods to synthesize these bonds through palladium-catalyzed transformations...
  15. New Mechanisms for Alkene Functionalization Using Redox Active Ligands
    ALISON NICOLE CAMPBELL; Fiscal Year: 2010
    ..The use of palladium catalysts containing oxidized redox-active ligands will be developed and applied to Pd-catalyzed aerobic ..
  16. New Carbon-based Ligands for Hydroamination and olefin metathesis catalysts
    Guy Bertrand; Fiscal Year: 2012
    ..They have already allowed for improving known palladium and ruthenium catalyzed processes, and even for promoting new metal catalyzed reactions...
  17. Synthesis of Macrolides, Steroids, Cyclopentanoids, etc.
    BARRY TROST; Fiscal Year: 2009
    ..Two new methods for accessing pyrans by simple one operation cycloaddition - like strategy relying on palladium and / or ruthenium catalysis may lead to biologically active targets containing such subunits illustrated by ..
  18. STEREOCONTROLLED SYNTHESIS OF BIOACTIVE ALKALOIDS
    VIRESH RAWAL; Fiscal Year: 2007
    ..of a wide range of indole alkaloids, but also in the development of useful new methodologies, particularly palladium-catalyzed processes and asymmetric Diels-Alder reactions...
  19. New Methods for Direct Carbon-Hydrogen Bond Functionalization
    OLAFS DAUGULIS; Fiscal Year: 2013
    ..In this project, palladium-catalyzed arylation, alkylation, vinylation, and alkynylation of unactivated sp3 C-H bonds will be explored in ..
  20. Mechanism and Rational Development of Catalytic Carbon-Carbon Bond-Forming Reacti
    John F Hartwig; Fiscal Year: 2013
    ..To achieve these short-term goals we will develop 1) palladium-catalyzed reactions of aryl halides with enolates that currently do not undergo coupling in high yields with ..
  21. Approaches for Directed Olefin Hydroamination
    Juana Du; Fiscal Year: 2013
    ..ligand framework, rhodium complexes of bidentate, bisphosphine ligands, and chelate-stabilized, ?2-olefin palladium complexes...
  22. Synthesis of the Apoptosis-Inducing Alkaloid Monanchocidin
    RYAN LLOYD PATMAN; Fiscal Year: 2013
    ..An innovative strategy is proposed to address the synthesis of this molecule employing palladium catalyzed asymmetric allylic alkylation (AAA) and a novel hydroguanidination/cyclization sequence...
  23. FLUORESCENT AND LARGE METAL CLUSTER COMBINATION PROBES
    Richard Powell; Fiscal Year: 1999
    ..Several new probes are proposed for the development during Phase I: 1) large platinum and palladium cluster complexes (1.8-3...
  24. Bond-Forming Methods via Dual-Metal Catalysis with Organogold Intermediates
    Suzanne A Blum; Fiscal Year: 2013
    ..The rationale for this approach is the demonstrated cooperative catalysis of gold and palladium, through which the PI established the synthetic potential of these dual-catalytic methods in the construction of ..
  25. Electrophilic Boranes: Directed Hydroboration, Borylation, and Related Reactions
    Edwin Vedejs; Fiscal Year: 2012
    ..In particular, palladium or nickel catalyzed Suzuki-Miyaura coupling of boronic acids is revolutionizing the way that experimental drugs ..
  26. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2010
    ..Public Health Relevance: Permanent implantation of radioactive seeds containing iodine-125, palladium-103, or cesium-131 in the prostate, also called brachytherapy, has become a popular form of radiation therapy ..
  27. EVALUATION OF MERCURY RELEASE FROM DENTAL AMALGAMS
    Toru Okabe; Fiscal Year: 2003
    ..A series of alloys will be prepared to test specific hypotheses about the effect of palladium (Pd) additions, silver (Ag) and tin (Sn) ratio, and copper (Cu) content...
  28. Tetrahydrofurans, Tetrahydropyrans and 2H-Furanones
    CHRISTOPHER SPILLING; Fiscal Year: 2009
    ..immediate goal is the efficient stereoselective synthesis of tetrahydrofurans, pyrans, and 2H-furanones via the palladium (0)-catalyzed addition of oxygen and carbon nucleophiles to phosphono allylic carbonates...
  29. The Direct Oxidative Trifluoromethylation of Simple Heteroaromatic Systems
    NATHAN THOMAS JUI; Fiscal Year: 2013
    ..More specifically, the proposed work would splice together individual aspects of two existing palladium catalyzed processes that individually accomplish CF3 cross coupling and C-H functionalization, respectively...
  30. STRUCTURE & PROPERTIES OF HIGH PALLADIUM DENTAL ALLOYS
    WILLIAM BRANTLEY; Fiscal Year: 2000
    DESCRIPTION (Adapted from the Applicant's Abstract): High-palladium alloys have become popular for metal-ceramic restorations and implant-supported prostheses, because of their much lower cost than gold alloys and their good mechanical ..
  31. Gamma Ray Spectroscopy for Dose Rate Constants
    Ravinder Nath; Fiscal Year: 2006
    Permanent implantation of either iodine-125 seeds or palladium-103 radioactive seeds in the prostate has become a popular form of radiation therapy for carefully selected prostate cancer patients...
  32. Palladium and Nickel Catalyzed C-H Activation/C-C Bond Formation
    Dipannita Kalyani; Fiscal Year: 2013
    ..Specifically this proposal seeks to develop palladium- and nickel-catalyzed methods for the construction of C-C bonds...
  33. The Synthesis of Bioactive Polycyclic Natural Products
    Brian M Stoltz; Fiscal Year: 2013
    ..The research proposed in this grant application is focused on a) the development of new palladium- and copper-catalyzed enantio-selective alkylation and protonation reactions that produce important building ..
  34. De Novo Synthesis of Oligosaccharides
    GEORGE A O'DOHERTY; Fiscal Year: 2012
    ..Our method revolves around the use of a highly stereoselective palladium catalyzed glycosylation (X = O: 2.1[unreadable]/2.4[unreadable] to 2.2 [unreadable]/2...
  35. Development of a Palladium-Catalyzed Direct N2-Arylation of Indazoles.
    Meredeth A McGowan; Fiscal Year: 2011
    ..1-4. The primary aim of the research project proposed here is the development of a highly selective, palladium- catalyzed N2-arylation of unprotected indazoles...
  36. NEW METHODS FOR ACYCLIC CONFORMATIONAL CONTROL
    David Shultz; Fiscal Year: 2000
    ..other transition metal mediated cyclization reactions such as carbopalladation, the Pauson Khand reaction and palladium catalyzed enzyme cycloisomerization...
  37. Novel Catalyst Systems
    Andrew Feiring; Fiscal Year: 2011
    ..are far from an exhaustive list but suggest the breadth and importance of the chemistry available from palladium catalysts. Palladium catalyzed reactions are ubiquitous in pharmaceutical process chemistry...
  38. A Mild and General Method for Pd and Cu Catalyzed Trifluoromethylation
    NICHOLE DANIELLE LITVINAS; Fiscal Year: 2012
    ..then be applied to a dual-catalyst system, where copper catalyzes the decarboxylation of trifluoroacetate and palladium catalyzes the cross-coupling...
  39. PALLADIUM CATALYZED FORMATION OF ARYLAMINE AND ARYLETHER
    John Hartwig; Fiscal Year: 2000
    ..The reactions they have developed are palladium.catalyzed aminations of aryl halides...
  40. Oxidative carbon-carbon bond formation: a synergy of enamine and Pd(II) catalysis
    AUBRY MILLER; Fiscal Year: 2007
    ..One challenging area of research in this field is the palladium(ll) mediated oxidative coupling of carbon nucleophiles with unactivated olefins...
  41. Catalytic Asymmetric Synthesis of Vinyl Chromans Using Palladium(II) Catalysts
    ANGELA CHRISTINE OLSON; Fiscal Year: 2010
    ..of trichloroacetimidates using a tethered phenol nucleophile will be examined using chiral cobalt oxazoline palladium(ll) catalysts...
  42. CYCLOMETALLATED DNA NUCLEASES
    JOHN SUGGS; Fiscal Year: 1990
    ..Recently, it has been discovered that a new palladium complex (formed by the cyclometallation of PdCl2 with the chelating organic ligand 2'-(2- methoxyphenyl) 1,..
  43. Development of a Pd Catalyzed 3+2 Annulation and Synthesis of Daphnicyclidin B
    JAMES ROBERT MANNING; Fiscal Year: 2011
    ..Another key step in the synthesis is a palladium catalyzed "3+2" annulation sequence that will be developed to install the hydroxyfulvene moiety...
  44. Highly Active Palladium Catalysts for Organic Synthesis
    Qiao Sheng Hu; Fiscal Year: 2004
    b>Palladium-catalyzed cross-coupling reactions, e.g...
  45. SYNTHESES OF MACROLIDES AND RELATED NATURAL PRODUCTS
    FREDERICK ZIEGLER; Fiscal Year: 1992
    ..Using Claisen rearrangements and palladium- mediated alkylations developed during the present granting period, efforts currently underway will be continued ..
  46. Utrasensitive bioassays using palladium catalyzed chemical amplification
    MARK LELENTAL; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): We propose to use novel Palladium Catalyzed Chemical Amplification (PdCCA) technology to develop ultra-sensitive bioassays that can detect very low concentrations of tumor biomarkers in blood...
  47. Synthesis of Amaryllidaceae Alkaloids via Palladium Catalysis
    Amanda Jones; Fiscal Year: 2009
    Project Summary: Stoichiometric palladium has been found to be capable of mediating the dearomatization of an aromatic precursor to form spirocyclic dienones...
  48. PALLADIUM CATALYZED SYNTHESIS OF C-NUCLEOSIDES
    G Daves; Fiscal Year: 1980
    A general synthesis of C-nucleosides (C-glycosides) by palladium-catalyzed coupling of suitable aromatic (heteroaromatic) derivatives to 1,2-unsaturated carbohydrate derivatives (glycals) will be developed...
  49. NEW METHODS FOR THE SYNTHESIS OF UNUSUAL AMINO ACIDS
    Gregory Cook; Fiscal Year: 1999
    ..first part of the proposal describes a study of the thermodynamic equilibration of 5-vinyloxazolines utilizing a palladium-catalyzed ring- opening /ring-closing reaction...
  50. Autoinductive Signal Amplification
    Scott T Phillips; Fiscal Year: 2013
    ..will be tested in the context of assays for water quality (fluoride will be the analyte), the purity of drugs (palladium will be the analyte), and for detecting influenza neuraminidase at levels that correspond to the first 24-48 h ..
  51. LEAD IN SALIVA
    WILLIFRIED SCHRAMM; Fiscal Year: 1992
    ..concentration of lead in saliva will be measured by graphite furnace atomic absorption spectroscopy (AAS) with palladium as a modifier. Lead concentrations in saliva are normally lower than concentrations in blood...
  52. PALLADIUM CATALYZED CYCLIZATION OF FUNCTIONALIZED DIENES
    ROSS WIDENHOEFER; Fiscal Year: 2003
    ..Realization of these goals would produce a powerful tool for the synthesis of naturally occurring and pharmacologically active carbocycles and heterocycles. ..
  53. PALLADIUM-CATALYZED ALKYLATION OF CYCLOALKENES
    RICHARD LAROCK; Fiscal Year: 1992
    ..Preliminary results in our laboratories indicate that the palladium-catalyzed allylic cross-coupling of cyclic alkenes and aryl, vinylic and alkynyl halides, as well as alkenyl ..
  54. SILOXANE COUPLINGS AND NATURAL PRODUCT SYNTHESIS
    Philip DeShong; Fiscal Year: 2001
    ..Applicant's Abstract) The long term goal of this research is to determine the scope and limitations of the palladium-catalyzed cross-coupling of hypervalent siloxanes with allylic ester and aryl derivatives...
  55. NEW FLUORESCENT X-RAY TUBES FOR MAMMOGRAPHY
    G Johnson; Fiscal Year: 1980
    ..Rhodium and palladium anodes have been constructed by depositing thin film on graphite and copper substrates...
  56. Agilent 5973 GC/MS System
    GARY MOLANDER; Fiscal Year: 2002
    ..Our current lack of such instrumentation negatively affects the ability to carry out many of these studies. This critical capability, in the form of an instrument for everyday analysis, is urgently needed. ..
  57. Catalytic Processes for Selective Organic Synthesis
    GARY MOLANDER; Fiscal Year: 2005
    ..4) Carbometalation/cyclization reactions will be explored utilizing organochromium species. 5) Ligands and catalytic systems designed for asymmetric synthesis will be explored. ..
  58. Design and Synthesis of Dinucleating Nitrogen Ligands
    JEREMY KODANKO; Fiscal Year: 2005
    ..The power of palladium catalyzed carbon-carbon bond forming processes will be employed to assemble these ligands in short order and ..
  59. Tandem Cycloaddition Chemistry of 2-Azoniaheterodienes
    SCOTT DENMARK; Fiscal Year: 2007
    ..abstract_text> ..
  60. Cross-Coupling Reactions of Organosilanols
    SCOTT DENMARK; Fiscal Year: 2009
    ..The opportunities for catalysis of the transmetalation from silicon to palladium will be studies...
  61. C-NUCLEOSIDES AS ANTI-AIDS AGENTS
    G Daves; Fiscal Year: 1991
    ..is coupled in a regio- and steriospecific manner with a pyrimidine aglycone derivative in the presence of palladium acetate...
  62. LARGE METAL CLUSTER AND CLUSTER-POLYMER IMMUNOPROBES
    Richard Powell; Fiscal Year: 1993
    New, molecular heavy metal cluster immunoprobes will be prepared, with platinum and palladium clusters 1.8 and 2.4 nm in diameter covalently conjugated to antibodies to give immunoelectron microscopy probes...
  63. Syntheses of Highly Substituted Pryocatechols
    WAYNE FRANCIS SCHNATTER; Fiscal Year: 2010
    ..The halocatechols, thus synthesized, will be subjected to palladium catalyzed coupling reactions to provide highly substituted catechol derivatives that would otherwise require ..
  64. Enantioselective Synthesis of Leustroducsin B
    THOMAS HUNTER; Fiscal Year: 2005
    ..This research project will: 1) investigate the synthesis of the 1,3-disubstituted cyclohexane moiety via a palladium-catalyzed asymmetric allylic alkylation (AAA), 2) study the viability of constructing the 1,3-anf/ diol moiety ..
  65. New C-C Bond Forming Reactions of Palladium Enolates
    ERIK ALEXANIAN; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): A new C-C bond forming reaction involving palladium enolates will be discussed...
  66. Catalytic, Regioselective C-H Activation/Oxidation of Substituted Arenes
    Erin Burger; Fiscal Year: 2007
    ..b>Palladium(ll) N-heterocyclic carbene complexes, which introduce very bulky substituents in close proximity to the ..
  67. NADH FLUORESCENCE IMAGING IN HEART
    CLYDE BARLOW; Fiscal Year: 1990
    ..I demonstrate that an enhanced instrument can produce complimentary images of tissue oxygen tension using unique palladium porphyrins...