mercury

Summary

Summary: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.

Top Publications

  1. ncbi The toxicology of mercury--current exposures and clinical manifestations
    Thomas W Clarkson
    Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, NY 14642, USA
    N Engl J Med 349:1731-7. 2003
  2. ncbi Association of oxidative stress with the formation of reproductive toxicity from mercury exposure on hermaphrodite nematode Caenorhabditis elegans
    Qiuli Wu
    Key Laboratory of Environmental Medicine Engineering in Ministry of Education, Medical School of Southeast University, Nanjing 210009, China
    Environ Toxicol Pharmacol 32:175-84. 2011
  3. pmc Adult women's blood mercury concentrations vary regionally in the United States: association with patterns of fish consumption (NHANES 1999-2004)
    Kathryn R Mahaffey
    Office of Science Coordination and Policy, Office of Prevention, Pesticides, and Toxic Substances, U S Environmental Protection Agency, Washington, DC, USA
    Environ Health Perspect 117:47-53. 2009
  4. ncbi Blood mercury levels in US children and women of childbearing age, 1999-2000
    Susan E Schober
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 289:1667-74. 2003
  5. ncbi Interactions between mercury and dissolved organic matter--a review
    Mahalingam Ravichandran
    AMEC Earth and Environmental Inc, 1395 S Marietta Parkway, Building 300, Ste 210, Marietta, GA 30067, USA
    Chemosphere 55:319-31. 2004
  6. ncbi Mercury exposure and public health
    Jack C Clifton
    Great Lakes Center for Children s Environmental Health, John H Stroger, Jr Hospital of Cook County, Chicago, IL, USA
    Pediatr Clin North Am 54:237-69, viii. 2007
  7. pmc Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort
    Emily Oken
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Epidemiol 167:1171-81. 2008
  8. ncbi The toxicology of mercury and its chemical compounds
    Thomas W Clarkson
    Department of Environmental Medicine, University of Rochester School of Medicine, New York, USA
    Crit Rev Toxicol 36:609-62. 2006
  9. ncbi Fish consumption in pregnancy, cord blood mercury level and cognitive and psychomotor development of infants followed over the first three years of life: Krakow epidemiologic study
    Wieslaw Jedrychowski
    Epidemiology and Preventive Medicine, Coll Med Jagiellonian University in Krakow, Poland
    Environ Int 33:1057-62. 2007
  10. ncbi Role of mercury toxicity in hypertension, cardiovascular disease, and stroke
    Mark C Houston
    Department of Medicine, Vanderbilt University School of Medicine, Division of Human Nutrition, Saint Thomas Medical Group, Saint Thomas Hospital, Nashville, TN, USA
    J Clin Hypertens (Greenwich) 13:621-7. 2011

Detail Information

Publications418 found, 100 shown here

  1. ncbi The toxicology of mercury--current exposures and clinical manifestations
    Thomas W Clarkson
    Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, NY 14642, USA
    N Engl J Med 349:1731-7. 2003
  2. ncbi Association of oxidative stress with the formation of reproductive toxicity from mercury exposure on hermaphrodite nematode Caenorhabditis elegans
    Qiuli Wu
    Key Laboratory of Environmental Medicine Engineering in Ministry of Education, Medical School of Southeast University, Nanjing 210009, China
    Environ Toxicol Pharmacol 32:175-84. 2011
    ..Thus, oxidative stress may be essential for the induction of reproductive deficits in Hg exposed hermaphrodite nematodes...
  3. pmc Adult women's blood mercury concentrations vary regionally in the United States: association with patterns of fish consumption (NHANES 1999-2004)
    Kathryn R Mahaffey
    Office of Science Coordination and Policy, Office of Prevention, Pesticides, and Toxic Substances, U S Environmental Protection Agency, Washington, DC, USA
    Environ Health Perspect 117:47-53. 2009
    The current, continuous National Health and Nutrition Examination Survey (NHANES) has included blood mercury (BHg) and fish/shellfish consumption since it began in 1999. NHANES 1999-2004 data form the basis for these analyses.
  4. ncbi Blood mercury levels in US children and women of childbearing age, 1999-2000
    Susan E Schober
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 289:1667-74. 2003
    ..The fetus is most sensitive to the adverse effects of exposure. The extent of exposure to methylmercury in US women of reproductive age is not known...
  5. ncbi Interactions between mercury and dissolved organic matter--a review
    Mahalingam Ravichandran
    AMEC Earth and Environmental Inc, 1395 S Marietta Parkway, Building 300, Ste 210, Marietta, GA 30067, USA
    Chemosphere 55:319-31. 2004
    Dissolved organic matter (DOM) interacts very strongly with mercury, affecting its speciation, solubility, mobility, and toxicity in the aquatic environment...
  6. ncbi Mercury exposure and public health
    Jack C Clifton
    Great Lakes Center for Children s Environmental Health, John H Stroger, Jr Hospital of Cook County, Chicago, IL, USA
    Pediatr Clin North Am 54:237-69, viii. 2007
    b>Mercury is a metal that is a liquid at room temperature. Mercury has a long and interesting history deriving from its use in medicine and industry, with the resultant toxicity produced...
  7. pmc Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort
    Emily Oken
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Am J Epidemiol 167:1171-81. 2008
    ..enrolled in 1999-2002, the authors studied associations of maternal second-trimester fish intake and erythrocyte mercury levels with children's scores on the Peabody Picture Vocabulary Test (PPVT) and Wide Range Assessment of Visual ..
  8. ncbi The toxicology of mercury and its chemical compounds
    Thomas W Clarkson
    Department of Environmental Medicine, University of Rochester School of Medicine, New York, USA
    Crit Rev Toxicol 36:609-62. 2006
    This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern...
  9. ncbi Fish consumption in pregnancy, cord blood mercury level and cognitive and psychomotor development of infants followed over the first three years of life: Krakow epidemiologic study
    Wieslaw Jedrychowski
    Epidemiology and Preventive Medicine, Coll Med Jagiellonian University in Krakow, Poland
    Environ Int 33:1057-62. 2007
    ..Although the maternal fish consumption is supposed to have beneficial effects on development of infants, it may be harmful for child cognitive development since fish is a common source of methylmercury...
  10. ncbi Role of mercury toxicity in hypertension, cardiovascular disease, and stroke
    Mark C Houston
    Department of Medicine, Vanderbilt University School of Medicine, Division of Human Nutrition, Saint Thomas Medical Group, Saint Thomas Hospital, Nashville, TN, USA
    J Clin Hypertens (Greenwich) 13:621-7. 2011
    b>Mercury has a high affinity for sulfhydryl groups, inactivating numerous enzymatic reactions, amino acids, and sulfur-containing antioxidants (N-acetyl-L-cysteine, alpha-lipoic acid, L-glutathione), with subsequent decreased oxidant ..
  11. ncbi Time trends in burdens of cadmium, lead, and mercury in the population of northern Sweden
    Maria Wennberg
    Department of Medicine, Skellefteå Hospital, 931 86 Skellefteå, Sweden
    Environ Res 100:330-8. 2006
    ..This study addresses time trends for the three toxic elements cadmium (Cd), mercury (Hg), and lead (Pb)...
  12. ncbi The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: mercury and lead
    Claudia Gundacker
    Institute of Medical Genetics, Medical University of Vienna, Währinger Strasse 10, A 1090 Vienna, Austria
    Mutat Res 705:130-40. 2010
    The heavy metals mercury and lead are well-known and significant developmental neurotoxicants. This review summarizes the genetic factors that modify their toxicokinetics...
  13. ncbi Fish consumption during pregnancy, prenatal mercury exposure, and anthropometric measures at birth in a prospective mother-infant cohort study in Spain
    Rosa Ramón
    CIBER en Epidemiología y Salud Pública, Barcelona, Spain
    Am J Clin Nutr 90:1047-55. 2009
    ..Birth size has been shown to be related to maternal fish intake, although the results are inconsistent...
  14. ncbi Immunology of mercury
    Jaya Vas
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Ann N Y Acad Sci 1143:240-67. 2008
    The heavy metal mercury is ubiquitously distributed in the environment resulting in permanent low-level exposure in human populations...
  15. ncbi Heavy metals (lead, cadmium and mercury) in maternal, cord blood and placenta of healthy women
    Iman Al-Saleh
    Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, PO Box 3354, Riyadh 11211, Saudi Arabia
    Int J Hyg Environ Health 214:79-101. 2011
    Lead, cadmium and mercury were measured in placental tissue, umbilical cord and maternal blood samples of 1578 women who delivered at the Al-Kharj King Khalid Hospital between 2005 and 2006...
  16. ncbi Total mercury in mushrooms and underlying soil substrate from the Borecka Forest, Northeastern Poland
    J Falandysz
    Department of Environmental Chemistry and Ecotoxicology, University of Gdansk, 18 Sobieskiego Str, PL 80 952 Gdansk, Poland
    Arch Environ Contam Toxicol 42:145-54. 2002
    Total mercury concentrations were determined by cold-vapor atomic absorption spectroscopy in 240 composite samples of the caps, 240 of the stalks, and 16 of the whole fruiting bodies of 13 species of wild mushrooms and in 256 samples of ..
  17. ncbi Biomarkers of environmental toxicity and susceptibility in autism
    David A Geier
    Institute of Chronic Illnesses, Inc, Silver Spring, Maryland, USA
    J Neurol Sci 280:101-8. 2009
    ..may result from a combination of genetic/biochemical susceptibilities in the form of a reduced ability to excrete mercury and/or increased environmental exposure at key developmental times...
  18. pmc Mercury exposure and risk of cardiovascular disease in two U.S. cohorts
    Dariush Mozaffarian
    Division of Cardiovascular Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    N Engl J Med 364:1116-25. 2011
    ..Beneficial effects of the ingestion of fish and selenium may also modify such effects...
  19. ncbi The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo
    Ya Wen Chen
    Institute of Toxicology, College of Medicine, National Taiwan University, No 1, Section 1, Jen Ai Road, Taipei, 10043, Taiwan
    Diabetes 55:1614-24. 2006
    ..b>Mercury is a well-known toxic metal that induces oxidative stress...
  20. pmc Blood organic mercury and dietary mercury intake: National Health and Nutrition Examination Survey, 1999 and 2000
    Kathryn R Mahaffey
    Office of Science Coordination and Policy, Office of Prevention, Pesticides and Toxic Substances, U S Environmental Protection Agency, 1200 Pennsylvania Avenue, Washington, DC 20460, USA
    Environ Health Perspect 112:562-70. 2004
    Blood organic mercury (i.e., methyl mercury) concentrations among 1,709 women who were participants in the National Health and Nutrition Examination Survey (NHANES) in 1999 and 2000 (1999-2000 NHANES) were 0...
  21. ncbi Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    Arterioscler Thromb Vasc Biol 25:228-33. 2005
    b>Mercury has been suggested to have negative effects on cardiovascular health...
  22. pmc Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels
    Claire de Burbure
    Unit of Industrial Toxicology and Occupational Medicine, Faculty of Medicine, Catholic University of Louvain, Clos Chapelle aux Champs 30, B 1200 Brussels, Belgium
    Environ Health Perspect 114:584-90. 2006
    Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little known...
  23. ncbi Neurobehavioral effects of dental amalgam in children: a randomized clinical trial
    Timothy A DeRouen
    Department of Dental Public Health Sciences, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    JAMA 295:1784-92. 2006
    Dental (silver) amalgam is a widely used restorative material containing 50% elemental mercury that emits small amounts of mercury vapor...
  24. pmc Mercury biogeochemical cycling in the ocean and policy implications
    Robert P Mason
    Department of Marine Sciences, University of Connecticut, 1080 Shennecossett Road, Groton, CT 06340, USA
    Environ Res 119:101-17. 2012
    Anthropogenic activities have enriched mercury in the biosphere by at least a factor of three, leading to increases in total mercury (Hg) in the surface ocean...
  25. ncbi Correlations between mercury concentrations in umbilical cord tissue and other biomarkers of fetal exposure to methylmercury in the Japanese population
    Mineshi Sakamoto
    Department of Epidemiology, National Institute for Minamata Disease, Kumamoto 867 0008, Japan
    Environ Res 103:106-11. 2007
    ..Our objective in this study is to examine the relationships of total mercury (THg) and MeHg concentrations between umbilical cord tissue and other tissues as biomarkers of fetal exposure to ..
  26. pmc Relation between cord blood mercury levels and early child development in a World Trade Center cohort
    Sally Ann Lederman
    Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 116:1085-91. 2008
    This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development.
  27. ncbi Suppressed adrenocortical responses and thyroid hormone levels in birds near a mercury-contaminated river
    Haruka Wada
    Department of Fisheries and Wildlife Sciences, Virginia Polytechnic Institute and State University, 100 Cheatham Hall, Blacksburg, Virginia 24061, USA
    Environ Sci Technol 43:6031-8. 2009
    Much of the research on sublethal, adverse effects of mercury (Hg) has focused on impairment of neurological function and reproduction in fish and fish-eating vertebrates...
  28. pmc Mercury bioavailability and bioaccumulation in estuarine food webs in the Gulf of Maine
    Celia Y Chen
    Department of Biological Sciences, HB 6044 Gilman Hall, Dartmouth College, Hanover, New Hampshire 03755, USA
    Environ Sci Technol 43:1804-10. 2009
    ..These results reveal the importance of both biogeochemical and ecological factors in determining the bioavailability and trophic transfer of MeHg in estuarine food webs...
  29. ncbi Mercury as a serious health hazard for children in gold mining areas
    Stephan Bose-O'Reilly
    Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT University for Health Sciences, Medical Informatics and Technology, Eduard Wallnoefer Zentrum I, A 6060 Hall i T, Austria
    Environ Res 107:89-97. 2008
    In many developing countries, mercury is used to extract gold from ore in small-scale mining areas...
  30. pmc Mercury-induced membranous nephropathy: clinical and pathological features
    Shi Jun Li
    Professor of Medicine, Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing 21002, China
    Clin J Am Soc Nephrol 5:439-44. 2010
    Long-term contact with mercury may induce membranous nephropathy (MN); however, the clinical pathologic features and pathogenesis of mercury-induced MN have not been investigated.
  31. pmc Comparison of hepatic and nephric total mercury concentrations between feral and ranch American mink (Neovison vison) from northwestern Poland
    Elżbieta Kalisińska
    Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70 111, Szczecin, Poland
    Bull Environ Contam Toxicol 88:802-6. 2012
    ..used in North America (where it originates from) as a sensitive indirect bioindicator in assessing the degree of mercury (Hg) contamination in terrestrial ecosystems...
  32. ncbi Exposure to mercury causes formation of male-specific structural deficits by inducing oxidative damage in nematodes
    Peidang Liu
    Key Laboratory of Environmental Medicine Engineering in Ministry of Education, Medical School of Southeast University, Nanjing 210009, China
    Ecotoxicol Environ Saf 79:90-100. 2012
    ..We here investigated the effects of mercury chloride exposure on development of males...
  33. ncbi Association of lead, mercury and cadmium with diabetes in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010
    S S Moon
    Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, South Korea
    Diabet Med 30:e143-8. 2013
    ..We investigated the association of heavy metals, including lead, mercury and cadmium, with diabetes in the Korean population.
  34. pmc Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/hyperactivity disorder-related behavior in children
    Sharon K Sagiv
    Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts 02118, USA
    Arch Pediatr Adolesc Med 166:1123-31. 2012
    To investigate the association of prenatal mercury exposure and fish intake with attention-deficit/hyperactivity disorder (ADHD)-related behavior.
  35. ncbi Mercury in the Tapajós River basin, Brazilian Amazon: a review
    J J Berzas Nevado
    Department of Analytical Chemistry and Food Technology, Faculty of Chemistry, University of Castilla La Mancha, Ciudad Real, Spain
    Environ Int 36:593-608. 2010
    This paper presents a review about mercury contamination and human exposure in the Tapajós River basin (Brazil), one of the major tributaries of the Amazon impacted by traditional gold mining from the mid 1980s...
  36. ncbi Highly sensitive and selective DNA-based detection of mercury(II) with α-hemolysin nanopore
    Shuang Wen
    Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China
    J Am Chem Soc 133:18312-7. 2011
    ..This sensing strategy opens new possibilities for detecting many types of analytes which have specific interactions with DNA molecules...
  37. ncbi Perinatal lead and mercury exposure in Austria
    Claudia Gundacker
    Institute of Medical Genetics, Medical University of Vienna, Währinger Strasse 10, 1090 Vienna, Austria
    Sci Total Environ 408:5744-9. 2010
    The heavy metals lead (Pb) and mercury (Hg) are ubiquitous environmental pollutants with high neurotoxic potential...
  38. ncbi Level of trace elements (copper, zinc, magnesium and selenium) and toxic elements (lead and mercury) in the hair and nail of children with autism
    Malarveni Damodaran Lakshmi Priya
    Department of Biochemistry, Bharathi Women s College, Chennai, 600 108 Tamil Nadu, India
    Biol Trace Elem Res 142:148-58. 2011
    ..levels of trace elements like copper (Cu), zinc (Zn), magnesium (Mg), and selenium (Se) and toxic elements like mercury (Hg), and lead (Pb) in the hair and nail samples of autistic children and to evaluate whether the level of these ..
  39. ncbi Colorimetric detection of mercuric ion (Hg2+) in aqueous media using DNA-functionalized gold nanoparticles
    Jae Seung Lee
    Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Il 60208 3113, USA
    Angew Chem Int Ed Engl 46:4093-6. 2007
  40. ncbi The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration
    F M Pecanha
    Departamento de Farmacologia, Universidad Autonoma de Madrid, Madrid, Spain
    J Physiol Pharmacol 61:29-36. 2010
    We have previously demonstrated that chronic exposure to low-dose of mercury induced endothelial dysfunction and increased vasoconstrictor responses...
  41. ncbi Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity
    Cristina M L Carvalho
    I Med, Faculty of Pharmacy, University of Lisbon, Av Prof Gama Pinto, 1649 003 Lisbon, Portugal
    J Biol Chem 283:11913-23. 2008
    b>Mercury toxicity mediated by different forms of mercury is a major health problem; however, the molecular mechanisms underlying toxicity remain elusive...
  42. ncbi The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction
    Mark C Houston
    Vanderbilt University School of Medicine, USA
    Altern Ther Health Med 13:S128-33. 2007
    b>Mercury, cadmium, and other heavy metals have a high affinity for sulfhydryl (-SH) groups, inactivating numerous enzymatic reactions, amino acids, and sulfur-containing antioxidants (NAC, ALA, GSH), with subsequent decreased oxidant ..
  43. ncbi Proximity to point sources of environmental mercury release as a predictor of autism prevalence
    Raymond F Palmer
    University of Texas Health Science Center, San Antonio Department of Family and Community Medicine, 7703 Floyd Curl Drive, San Antonio Texas, Mail Code 7794, TX 78229 3900, USA
    Health Place 15:18-24. 2009
    The objective of this study was to determine if proximity to sources of mercury pollution in 1998 were related to autism prevalence in 2002...
  44. pmc The role of environmental mercury, lead and pesticide exposure in development of amyotrophic lateral sclerosis
    Frank O Johnson
    Center for Integrative Toxicology and Neuroscience Program and Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, United States
    Neurotoxicology 30:761-5. 2009
    ..although circumstantial epidemiological evidence has implicated exposure to heavy metals such as lead and mercury, industrial solvents and pesticides especially organophosphates and certain occupations such as playing ..
  45. pmc Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon Sulfolobus solfataricus by use of gene disruption
    James Schelert
    Beadle Center for Genetics, University of Nebraska, Lincoln, Nebraska 68588 0666, USA
    J Bacteriol 186:427-37. 2004
    b>Mercury resistance mediated by mercuric reductase (MerA) is widespread among bacteria and operates under the control of MerR...
  46. pmc Maternal fish consumption, hair mercury, and infant cognition in a U.S. Cohort
    Emily Oken
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA
    Environ Health Perspect 113:1376-80. 2005
    Fish and other seafood may contain organic mercury but also beneficial nutrients such as n-3 polyunsaturated fatty acids. We endeavored to study whether maternal fish consumption during pregnancy harms or benefits fetal brain development...
  47. ncbi Ecological effects, transport, and fate of mercury: a general review
    D W Boening
    Lockheed Martin Environmental Services Assistance Team, Port Orchard, WA 98366, USA
    Chemosphere 40:1335-51. 2000
    b>Mercury at low concentrations represents a major hazard to microorganisms. Inorganic mercury has been reported to produce harmful effects at 5 microg/l in a culture medium...
  48. ncbi Mercury advisories and household health trade-offs
    Jay P Shimshack
    Department of Economics, Tulane University, New Orleans, LA 70118, USA
    J Health Econ 29:674-85. 2010
    ..Yet, some scientists speculate that the Food and Drug Administration's prominent mercury in fish advisory may have harmed public health. Lower mercury intakes reduce neurological toxicity risks...
  49. pmc Interaction between GSTM1/GSTT1 polymorphism and blood mercury on birth weight
    Bo Eun Lee
    Department of Preventive Medicine, School of Medicine, Ewha Woman s University, Seoul, Korea
    Environ Health Perspect 118:437-43. 2010
    b>Mercury (Hg) is toxic to both the reproductive and nervous systems. In addition, glutathione S-transferases (GSTs), which conjugate glutathione to a variety of electrophilic compounds, are involved in the detoxification of Hg.
  50. pmc Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study
    Gary J Myers
    University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
    Neurotoxicology 30:338-49. 2009
    Fish is an important source of nutrition worldwide. Fish contain both the neurotoxin methyl mercury (MeHg) and nutrients important for brain development...
  51. pmc Bioaccumulation syndrome: identifying factors that make some stream food webs prone to elevated mercury bioaccumulation
    Darren M Ward
    Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA
    Ann N Y Acad Sci 1195:62-83. 2010
    b>Mercury is a ubiquitous contaminant in aquatic ecosystems, posing a significant health risk to humans and wildlife that eat fish...
  52. ncbi Fish consumption and myocardial infarction: a second prospective biomarker study from northern Sweden
    Maria Wennberg
    Department of Medicine, Skellefteå Hospital, Skellefteå, Sweden
    Am J Clin Nutr 93:27-36. 2011
    ..A beneficial role of fish consumption on the risk of myocardial infarction (MI) has been reported and is mostly ascribed to n-3 (omega-3) fatty acids. However, fish also contains methylmercury, which may increase the risk of MI...
  53. ncbi Bioaccumulation of methylmercury versus inorganic mercury in rice (Oryza sativa L.) grain
    Hua Zhang
    State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang, 550002, China
    Environ Sci Technol 44:4499-504. 2010
    b>Mercury (Hg) bioaccumulation in aquatic food webs has been much studied, motivated from high Hg levels found in many fish species important for human consumption...
  54. pmc Sources of mercury exposure for U.S. seafood consumers: implications for policy
    Noelle E Selin
    Joint Program on the Science and Policy of Global Change, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 4307, USA
    Environ Health Perspect 118:137-43. 2010
    ..Recent policies attempting to reduce adverse effects of methylmercury exposure from fish consumption in the United States have targeted reductions in anthropogenic emissions from U.S. sources...
  55. ncbi Present-day mercury resistance transposons are common in bacteria preserved in permafrost grounds since the Upper Pleistocene
    Sofia Mindlin
    Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia
    Res Microbiol 156:994-1004. 2005
    Transposons closely related to mercury resistance transposons Tn5041, Tn5053, and Tn5056, which have been previously described in present-day bacteria, were detected in a survey of 12 mercury-resistant Pseudomonas strains isolated from ..
  56. ncbi Highly sensitive electrochemical sensor for mercury(II) ions by using a mercury-specific oligonucleotide probe and gold nanoparticle-based amplification
    Zhiqiang Zhu
    Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, China
    Anal Chem 81:7660-6. 2009
    ..electrochemical sensor for the detection of Hg(2+) ions in aqueous solution by using a thymine (T)-rich, mercury-specific oligonucleotide (MSO) probe and gold nanoparticles (Au NPs)-based signal amplification...
  57. ncbi Reducing the uncertainty in measurement and understanding of mercury in the atmosphere
    Mae Gustin
    Department of Natural Resources and Environmental Science, University of Nevada Reno, USA
    Environ Sci Technol 44:2222-7. 2010
    Elucidating the extent of mercury in the atmosphere requires deployment of robust and sensitive instruments.
  58. ncbi How can a chemical element elicit complex immunopathology? Lessons from mercury-induced autoimmunity
    Michael Schiraldi
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, 19140, United States
    Trends Immunol 30:502-9. 2009
    ..Although the ultimate pathophysiology of this model remains mysterious, recent studies have started to elucidate the mechanisms by which heavy metal exposure leads to immune activation and loss of self-tolerance...
  59. ncbi Antarctic springtime depletion of atmospheric mercury
    Ralf Ebinghaus
    Institute for Coastal Research Physical and Chemical Analysis, GKSS Research Centre Geesthacht, Germany
    Environ Sci Technol 36:1238-44. 2002
    Unlike other heavy metals that are inherently associated with atmospheric aerosols, mercury in ambient air exists predominantly in the gaseous elemental form...
  60. ncbi Cysteine metabolism and metal toxicity
    D Quig
    Doctor s Data, Inc, West Chicago, IL, USA
    Altern Med Rev 3:262-70. 1998
    ..The sulfhydryl-reactive metals (mercury, cadmium, lead, arsenic) are particularly insidious and can affect a vast array of biochemical and nutritional ..
  61. ncbi The role of weather in mediating the effect of mercury exposure on reproductive success in tree swallows
    Kelly K Hallinger
    Department of Biology, College of William and Mary, Institute for Integrative Bird Behavior Studies, Williamsburg, VA 23187, USA
    Ecotoxicology 20:1368-77. 2011
    b>Mercury is a heavy metal that has contaminated countless ecosystems throughout the world...
  62. pmc Potential for mercury reduction by microbes in the high arctic
    Alexandre J Poulain
    Groupe de Recherche Inter universitaire en Limnologie GRIL, Departement des Sciences Biologiques, Universite de Montreal, C P 6128, Succursale Centre Ville, Pavillon Marie Victorin, Montreal, Quebec, Canada H3C 3J7
    Appl Environ Microbiol 73:2230-8. 2007
    ..that microbes in the high Arctic possess and express diverse merA genes, which specify the reduction of ionic mercury [Hg(II)] to the volatile elemental form [Hg(0)]...
  63. ncbi Blood mercury levels in autism spectrum disorder: Is there a threshold level?
    David A Geier
    Institute of Chronic Illnesses, Inc, Silver Spring, MD, USA
    Acta Neurobiol Exp (Wars) 70:177-86. 2010
    b>Mercury (Hg) may significantly impact the pathogenesis of autism spectrum disorders (ASDs)...
  64. ncbi Marine biogeochemical cycling of mercury
    William F Fitzgerald
    Department of Marine Sciences, University of Connecticut, 1080 Shenecosett Road, Groton, Connecticut 06340, USA
    Chem Rev 107:641-62. 2007
  65. ncbi Dynamic oxidation of gaseous mercury in the Arctic troposphere at polar sunrise
    Steve E Lindberg
    Environmental Sciences Division, Oak Ridge National Laboratory, Tennessee 37831 6038, USA
    Environ Sci Technol 36:1245-56. 2002
    Gaseous elemental mercury (Hg0) is a globally distributed air toxin with a long atmospheric residence time. Any process that reduces its atmospheric lifetime increases its potential accumulation in the biosphere...
  66. ncbi Mercury pollution and childhood in Amazon riverside villages
    M C N Pinheiro
    Nucleo de Medicina Tropical, Universidade Federal do Para, Av Generalíssimo Deodoro, 92 Umarizal, 66055 240 Belém, PA, Brazil
    Environ Int 33:56-61. 2007
    b>Mercury is a hazardous metal responsible for environmental contamination and human intoxication...
  67. ncbi Metals and women's health
    M Vahter
    Institute of Environmental Medicine, Karolinska Institutet, Sweden
    Environ Res 88:145-55. 2002
    ..The present work aims at reviewing exposure and health effects of cadmium, nickel, lead, mercury, and arsenic manifested differently in women than in men...
  68. pmc Global source-receptor relationships for mercury deposition under present-day and 2050 emissions scenarios
    Elizabeth S Corbitt
    Department of Earth and Planetary Sciences, Harvard University, Cambridge, Massachusetts 02138, United States
    Environ Sci Technol 45:10477-84. 2011
    Global policies regulating anthropogenic mercury require an understanding of the relationship between emitted and deposited mercury on intercontinental scales...
  69. pmc Seafood consumption and blood mercury concentrations in Jamaican children with and without autism spectrum disorders
    Mohammad H Rahbar
    Division of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health at Houston, Houston, TX 77030, USA
    Neurotox Res 23:22-38. 2013
    b>Mercury is a toxic metal shown to have harmful effects on human health...
  70. pmc Prenatal mercury contamination: relationship with maternal seafood consumption during pregnancy and fetal growth in the 'EDEN mother-child' cohort
    Peggy Drouillet-Pinard
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Team Epidemiology of Obesity, Diabetes and Renal Disease over the Lifecourse, Villejuif, France
    Br J Nutr 104:1096-100. 2010
    ..There was no consistent association between Hg level and fetal growth. Taking into account Hg level did not modify associations between seafood intake and fetal growth...
  71. ncbi Mercury-induced oxidative stress and impact on antioxidant enzymes in Chlamydomonas reinhardtii
    Abdelrahman Elbaz
    Department of Biochemistry and Molecular Biology, College of Life Science, Nanjing Agricultural University, Nanjing, 210095, China
    Ecotoxicology 19:1285-93. 2010
    Investigation of mercury toxicology in green algae is of great importance from ecological point of view, because mercury has become a major contaminant in recent years...
  72. ncbi Mercury distribution across 14 U.S. Forests. Part I: spatial patterns of concentrations in biomass, litter, and soils
    D Obrist
    Desert Research Institute, Reno, NV, USA
    Environ Sci Technol 45:3974-81. 2011
    Results from a systematic investigation of mercury (Hg) concentrations across 14 forest sites in the United States show highest concentrations in litter layers, strongly enriched in Hg compared to aboveground tissues and indicative of ..
  73. ncbi An assessment of costs and benefits associated with mercury emission reductions from major anthropogenic sources
    Jozef M Pacyna
    NILU Norwegian Institute for Air Research, Kjeller, Norway
    J Air Waste Manag Assoc 60:302-15. 2010
    Several measures are available for reducing mercury emissions; however, these measures differ with regard to emission control efficiency, cost, and environmental benefits obtained through their implementation...
  74. ncbi Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice
    Andressa Sausen de Freitas
    Departamento de Quimica, Centro de Ciencias Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, CEP 97105 900 RS, Brazil
    Brain Res Bull 79:77-84. 2009
    ..levels of thiobarbituric acid reactive substances (TBARS), non-protein thiols (NPSH), ascorbic acid content, mercury concentrations and activities of antioxidant enzymes (glutathione peroxidase (GPx), catalase (CAT) and superoxide ..
  75. ncbi Prenatal mercury exposure in a multicenter cohort study in Spain
    R Ramon
    Dirección General de Salud Publica, Conselleria de Sanitat, Valencia, Avda Catalunya 21, 46020 Valencia, Spain
    Environ Int 37:597-604. 2011
    b>Mercury is a ubiquitous heavy metal that may negatively affect human health. It is desirable to investigate mercury exposure in vulnerable populations.
  76. ncbi Effects of mercury exposure on the reproductive success of tree swallows (Tachycineta bicolor)
    Rebecka L Brasso
    Department of Biology, Institute for Integrative Bird Behavior Studies, The College of William and Mary, P O Box 8795, Williamsburg, VA 23187 8795, USA
    Ecotoxicology 17:133-41. 2008
    ..established in the headwaters of the Shenandoah River, Virginia, USA to assess the accumulation and effects of mercury contamination on birds that eat emergent aquatic insects...
  77. ncbi Accumulation of mercury and methylmercury by mushrooms and earthworms from forest soils
    Stephan R Rieder
    Rhizosphere Processes Group, Swiss Federal Research Institute WSL, 8903 Birmensdorf, Switzerland
    Environ Pollut 159:2861-9. 2011
    ..Earthworms contained similar Hg concentrations (1.04 mg Hg kg(-1) dw) whereas endogeic earthworms accumulated highest amounts of Hg and methyl-Hg...
  78. pmc Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury
    Adriana M Torres
    Farmacologia, Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional de Rosario, Consejo Nacional de Investigaciones Cientificas y Tecnicas, 2000 Rosario, Argentina
    J Biol Chem 286:26391-5. 2011
    The primary site of mercury-induced injury is the kidney due to uptake of the reactive Hg(2+)-conjugated organic anions in the proximal tubule...
  79. ncbi Content and bioconcentration factors of mercury by Parasol Mushroom Macrolepiota procera
    Jerzy Falandysz
    Department of Environmental Chemistry, University of Gdansk, Gdansk, Poland
    J Environ Sci Health B 42:735-40. 2007
    ..and spatially distant sites across Poland were examined to know content and bioconcentration potential of mercury by this species. The total mercury content of the caps of Parasol Mushroom for the particular sites ranged from 1...
  80. ncbi A thermophilic bacterial origin and subsequent constraints by redox, light and salinity on the evolution of the microbial mercuric reductase
    Tamar Barkay
    Department of Biochemistry and Microbiology, Rutgers University, Lipman Hall, New Brunswick, NJ 08901, USA
    Environ Microbiol 12:2904-17. 2010
    Mercuric reductase (MerA) is central to the mercury (Hg) resistance (mer) system, catalyzing the reduction of ionic Hg to volatile Hg(0)...
  81. pmc Metallothioneins are required for formation of cross-adaptation response to neurobehavioral toxicity from lead and mercury exposure in nematodes
    Boping Ye
    College of Life Science and Technology, China Pharmaceutical University, Nanjing, China
    PLoS ONE 5:e14052. 2010
    ..Therefore, the normal formation of cross-adaptation response to neurobehavioral toxicity induced by metal exposure may need the enough accumulation of MTs protein in animal tissues...
  82. ncbi Toenail mercury and dietary fish consumption
    Judy R Rees
    Dartmouth College Center for Environmental Health Sciences, Department of Community and Family Medicine Biostatistics and Epidemiology and Norris Cotton Cancer Center, Lebanon, New Hampshire 03756, USA
    J Expo Sci Environ Epidemiol 17:25-30. 2007
    New England is one of three areas in the United States with the highest annual deposition of mercury, an established environmental pollutant with a variety of health effects...
  83. ncbi The movement of aquatic mercury through terrestrial food webs
    Daniel A Cristol
    Institute for Integrative Bird Behavior Studies, Department of Biology, College of William and Mary, Williamsburg, VA 23185, USA
    Science 320:335. 2008
    b>Mercury has contaminated rivers worldwide, with health consequences for aquatic organisms and humans who consume them. Researchers have focused on aquatic birds as sentinels for mercury...
  84. ncbi Identification and distribution of mercury species in rat tissues following administration of thimerosal or methylmercury
    Jairo L Rodrigues
    Faculdade de Ciências Farmacêuticas de Ribeirão Preto FCFRP, Departamento de Analises Clinicas, Toxicologicas e Bromatologicas, USP, Avenida do Café, S N, Monte Alegre, Ribeirao Preto, SP 14040 903, Brazil
    Arch Toxicol 84:891-6. 2010
    ..Sodium ethyl mercury thiosalicylate, thimerosal (TM) is an ethylmercury (Et-Hg)-containing preservative that has been used in ..
  85. ncbi Preliminary findings on the effects of occupational exposure to mercury vapor below safety levels on visual and neuropsychological functions
    Mirella Telles Salgueiro Barboni
    Neuroscience and Behavior, University of Sao Paulo, Sao Paulo, Brazil
    J Occup Environ Med 51:1403-12. 2009
    ..To evaluate whether there are visual and neuropsychological decrements in workers with low exposure to Hg vapor...
  86. pmc Fish consumption and mercury exposure among Louisiana recreational anglers
    Rebecca A Lincoln
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 119:245-51. 2011
    ..Methylmercury (MeHg) exposure assessments among average fish consumers in the United States may underestimate exposures among U.S. subpopulations with high intakes of regionally specific fish...
  87. ncbi Mercury bio-concentration potential of Larch Bolete, Suillus grevillei, mushroom
    K Chudzyński
    Department of Environmental Chemistry, Ecotoxicology and Food Toxicology, University of Gdansk, 18 Sobieskiego Str, 80 952, Gdansk, Poland
    Bull Environ Contam Toxicol 83:275-9. 2009
    ..of Larch Bolete fruiting bodies as well as the lack of any statistically significant differences in soil mercury contamination among the examined sites. Values of 1.0 microg Hg/g dw for pool of caps and 2...
  88. ncbi National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population
    Nam Soo Kim
    Institute of Environmental and Occupational Medicine, College of Medicine, Soonchunhyang University, 646 Eupnae ri, Shinchang myun, Asan, Choongnam, 336 745, Korea
    Int Arch Occup Environ Health 84:53-63. 2011
    To assess the extent of exposure to lead, cadmium, and mercury in the Korean general adult population using a representative sample.
  89. ncbi A 30-year follow-up of residual effects on New Zealand School Dental Nurses, from occupational mercury exposure
    Linda Jones
    School of Psychology, Massey University, Wellington, New Zealand
    Hum Exp Toxicol 26:367-74. 2007
    This paper reports possible residual adverse effects from occupational mercury exposure in dentistry, Thirty years ago, the all-women exposed group worked with both silver and copper amalgam filling material without protective gloves or ..
  90. pmc Mercury exposure: medical and public health issues
    Kathryn R Mahaffey
    Trans Am Clin Climatol Assoc 116:127-53; discussion 153-4. 2005
    b>Mercury exposure is widespread in the United States with methylmercury as the predominant chemical species and fish and shellfish as the source...
  91. ncbi Total blood mercury concentrations in the U.S. population: 1999-2006
    Kathleen L Caldwell
    Division of Laboratory Sciences, National Center for Environmental Health, CDC, 4770 Buford Highway, NE, Mailstop F 18, Atlanta, GA 30341, USA
    Int J Hyg Environ Health 212:588-98. 2009
    ..081 vs. 0.850microg/L, p<0.0001) and in Mexican American women (1.081 vs. 0.70microg/L, p<0.0001)...
  92. pmc Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium
    Yuzhao Zhou
    Center for Devices and Radiological Health, U S Food and Drug Administration, White Oak Life Sciences Laboratory, Silver Spring, MD 20993, USA
    Toxicol Sci 101:159-70. 2008
    ..Male Sprague-Dawley rats were injected with a range of doses of gentamicin, mercury (Hg; HgCl2), or chromium (Cr; K2Cr2O7)...
  93. ncbi Intervention study on cardiac autonomic nervous effects of methylmercury from seafood
    Kozue Yaginuma-Sakurai
    Department of Environmental Health Sciences, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Sendai 980 8575, Japan
    Neurotoxicol Teratol 32:240-5. 2010
    ..In the experimental group, mean hair mercury levels, determined before and after the dietary methylmercury exposure and after 15-week wash-out period ..
  94. ncbi A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. II. Application and validation of the model in humans
    G Carrier
    Chair in Toxicological Risk Assessment for Human Health, Department of Environmental and Occupational Health, Faculty of Medicine, Universite de Montreal, Main Station, Montreal, Quebec, H3C 3J7, Canada
    Toxicol Appl Pharmacol 171:50-60. 2001
    ..of this study was to develop a biologically based dynamical model describing the disposition kinetics of methyl mercury and its inorganic mercury metabolites in humans following different methyl mercury exposure scenarios...
  95. ncbi Low dose mercury and heart rate variability among community residents nearby to an industrial complex in Korea
    Sinye Lim
    Department of Occupational and Environmental Medicine, College of Medicine, Kyunghee University, Seoul, Republic of Korea
    Neurotoxicology 31:10-6. 2010
    The effect of mercury on the cardiovascular system has been recently reported, but the mechanisms and its nature, especially in low dose ranges, still need to be confirmed...
  96. ncbi Socioeconomic consequences of mercury use and pollution
    Edward B Swain
    Minnesota Pollution Control Agency, St Paul 55155, USA
    Ambio 36:45-61. 2007
    In the past, human activities often resulted in mercury releases to the biosphere with little consideration of undesirable consequences for the health of humans and wildlife...
  97. ncbi MercuryII-mediated formation of thymine-HgII-thymine base pairs in DNA duplexes
    Yoko Miyake
    Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Minami Ohsawa 1 1, Hachioji, Tokyo 192 0397 Japan
    J Am Chem Soc 128:2172-3. 2006
    ..Following this finding, we prepared DNA duplexes containing metal-mediated base pairs at the desired sites, as well as novel double helical architectures consisting only of thymine-HgII-thymine pairs...
  98. ncbi Mercury cycling in stream ecosystems. 1. Water column chemistry and transport
    Mark E Brigham
    U S Geological Survey, 2280 Woodale Drive, Mounds View, Minnesota 55112, USA
    Environ Sci Technol 43:2720-5. 2009
    We studied total mercury (THg) and methylmercury (MeHg) in eight streams, located in Oregon, Wisconsin, and Florida, that span large ranges in climate, landscape characteristics, atmospheric Hg deposition, and water chemistry...
  99. ncbi Patterns and interpretation of mercury exposure in freshwater avian communities in northeastern north America
    David C Evers
    BioDiversity Research Institute, 19 Flaggy Meadow Rd, Gorham, ME 04038, USA
    Ecotoxicology 14:193-221. 2005
    A large data set of over 4,700 records of avian mercury (Hg) levels in northeastern North America was compiled and evaluated...
  100. ncbi Low blood levels of lead and mercury and symptoms of attention deficit hyperactivity in children: a report of the children's health and environment research (CHEER)
    Mina Ha
    Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea
    Neurotoxicology 30:31-6. 2009
    The goal of this study was to examine the association between low levels of lead and mercury in blood and symptoms of attention-deficit hyperactivity disorder (ADHD) among Korean children.
  101. ncbi Lead, zinc, cadmium, mercury, selenium and copper in Greenland caribou and reindeer (Rangifer tarandus)
    P Aastrup
    Department of Arctic Environment, National Environmental Research Institute, Copenhagen, Denmark
    Sci Total Environ 245:149-59. 2000
    ..The levels of lead, zinc, cadmium, mercury, selenium, and copper were determined, and analyzed in relation to location, two seasons, age and year of ..

Research Grants67

  1. Clinical , Mechanical and Chemical Evaluation of Amalgam and ART Restorations
    Lilliam Marie Pinzon; Fiscal Year: 2013
    ..Amalgam is an alloy of mercury with another metal (silver) used traditionally by dentists to fill cavities in teeth...
  2. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..Abnormal levels of bio-essential metals (iron, copper, and zinc) as well as toxic trace elements (mercury, lead, cadmium, and arsenic) are known to be associated with many health disorders such as cancer, cognitive ..
  3. Human developmental toxicity of metal mixture exposure from e-waste recycling
    Aimin Chen; Fiscal Year: 2010
    ..E-waste contains high levels of several metals (lead [Pb], mercury [Hg], cadmium [Cd], chromium [Cr], manganese [Mn], etc...
  4. Epidemiological Research on Autism in Jamaica
    Mohammad H Rahbar; Fiscal Year: 2010
    ..also conduct a pilot age and sex matched case-control study to investigate whether environmental exposures to mercury, lead, arsenic and cadmium play a role in autism...
  5. Epidemiological Research on Autism in Jamaica - Phase II
    Mohammad H Rahbar; Fiscal Year: 2013
    ..in Jamaica to investigate the role of the glutathione-S-transferase (GST) genes and five heavy metals (lead, mercury, arsenic, cadmium, manganese) in relation to ASD...
  6. Methylmercury exposure, mercury metabolism genotypes, and risk of adult glioma
    Kathleen M Egan; Fiscal Year: 2013
    ..Given the high variability o MeHg content in fish and individual differences in mercury metabolism, measuring MeHg levels in nail clippings will provide a more accurate measurement of MeHg exposure ..
  7. International Training and Research in Environmental and Occupational Health
    NELSON K STEENLAND; Fiscal Year: 2012
    ..Two other Peruvian Fogarty studies funded via Emory showed a similar situation with informal gold miners using mercury and nurses using cytostatic drugs. An additional specific problem in Peru and Chile is altitude sickness...
  8. Soft Metal, Disulfide, and Cysteine Stresses in Escherichia coli
    James A Imlay; Fiscal Year: 2013
    ..Some of these metals- notably silver and mercury-have a long history of being used as antibiotics...
  9. Immunotoxicity in Humans with Lifetime Exposure to Ocean Pullutants
    PHILIPPE ADAM GRANDJEAN; Fiscal Year: 2013
    ..provided by applicant) Seafood is a main source of human exposure to environmental pollutants, such as methyl mercury and lipophilic contaminants, including polychlorinated biphenyls (PCBs)...
  10. Toxic Metal Complexation by de Novo Designed Peptides
    Vincent L Pecoraro; Fiscal Year: 2013
    Abstract Heavy metal poisoning by elements such as mercury, lead, cadmium, and arsenic is a significant human health problem...
  11. Sorbents for Toxic-Metal Removal in Pharmaceutical Development and Manufacture
    GIRISH SRINIVAS; Fiscal Year: 2013
    ..organo-metallic compounds are extremely toxic, producing neurological effects similar to those induced by methyl mercury and tetraethyl lead...
  12. Strategies for Heavy Metal Detoxification
    Gerard Parkin; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Mercury and lead are pervasive in the environment and pose a severe risk to human health worldwide...
  13. The Charge Study: Childhood Autism Risks from Genetics and the Environment
    Irva Hertz-Picciotto; Fiscal Year: 2013
    ..Fieldwork began in 2003, and by now CHARGE has published widely on exposures such as air pollution, mercury, flame retardants, maternal nutritional status in the peri-conception, untreated fever during pregnancy, ..
  14. Field Validation of New XRF Analyzers: Assessing Personal Exposure to Metals
    PATRICK JEREMY PARSONS; Fiscal Year: 2012
    ..obtained with this new analyzer under field conditions by deploying it in an on-going biomonitoring study of mercury exposure in subjects of ethnic Chinese background living in the Capital Region (Albany- Schenectady-Troy) of New ..
  15. Base-selective heavy atom labels for electron microscopy-based DNA sequencing
    F D Toste; Fiscal Year: 2012
    ..Incorporation of gold (ZAu = 79) and mercury (ZHg = 80) atoms through direct metal-metal bonds to the osmium atoms will also be explored...
  16. Genetic Susceptibility to Mercury Toxicity in Children
    James S Woods; Fiscal Year: 2012
    ..that are known to be associated with neurobehavioral deficits in adults, on the neurotoxic effects of elemental mercury (Hg0) exposure from dental amalgam fillings in children...
  17. Environmental exposure to metal mixtures and kidney disease
    Mary Fox; Fiscal Year: 2009
    ..The metals are barium, cadmium, cobalt, lead, mercury, molybdenum, and uranium...
  18. Short Wavelength UV Sources for Treatment of Psoriasis
    JOSEPH SMART; Fiscal Year: 2006
    ..Today, these light sources are primarily broadband high pressure mercury lamps, mercury xenon, mercury argon and deuterium sources or excimer lasers...
  19. Factors Modifying the Toxicity of Methylmercury in a Fish-Eating Population
    Philip W Davidson; Fiscal Year: 2013
    ..The proposed project will create a Virtual Consortium with the theme: Genetic Modifiers of Mercury Toxicity and Nutrient Metabolism. The consortium will include two new partners. Dr...
  20. Sorbents for Toxic-Metal Removal in Pharmaceutical Development and Manufacture
    GIRISH SRINIVAS; Fiscal Year: 2011
    ..coordination compounds of the Pt-group metals have been found to be extremely toxic, producing effects similar to mercury and lead...
  21. Effects of Methylmercury on Neuronal Cell Migration
    Hitoshi Komuro; Fiscal Year: 2010
    ..it has revealed that methylmercury (MeHg) induced congenital intoxication via the transplacental transfer of mercury to the fetus. The term fetal Minamata disease (FMD) was used to describe such medical phenomenon...
  22. Immune dysfunction associated with early life heavy metal exposure
    EMILY CATHERINE SOMERS; Fiscal Year: 2013
    ..Hu), which has been extensively characterized in terms of heavy metal exposures, including mercury (prenatal and childhood measurement)...
  23. Understanding the influence of n-3 PUFA on pro-inflammatory aspects of mercury
    Allen J Rosenspire; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The environmental heavy metal contaminant mercury (Hg) is a potent neurotoxin and immunomodulator that at low exposure levels has been implicated as a factor contributing to cognitive impairment as ..
  24. The Nerve Terminal as the Site of Action for Type-2 Alkenes
    RICHARD MICHAEL LOPACHIN; Fiscal Year: 2013
    ..g., acrolein, ACR, methyl mercury) that produce cytotoxicity by reacting with nucleophilic targets on macromolecules...
  25. Colloidal Quantum Dot/Well Near-Infrared NanoLabels
    Hua Mao; Fiscal Year: 2010
    ..Most NIR bio-medical labels based on quantum dots reported in literature today are based on cadmium, mercury, or lead elements, which are extremely toxic and unlikely to make into the real life applications because of the ..
  26. Maternal Methylmercury Exposure Through Rice Ingestion and Offspring Development
    SARAH ROTHENBERG; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Mercury is a global pollutant and potent neurotoxin. Methylmercury is one of the most toxic forms of mercury due to its ability to cross the blood brain and placental barriers...
  27. Influence of human gene variants on the effects of developmental MeHg exposure
    Michael J Carvan; Fiscal Year: 2010
    ..It is estimated that as many as 15% of American women of childbearing age have total blood mercury concentrations at a level above that associated with loss of IQ (>3.5 <g/L) in their children...
  28. Measuring the Cost of Environmental Health Risks: Evidence from Neighborhoods Nea
    LUCAS W DAVIS; Fiscal Year: 2010
    ..Power plants also emit low levels of uranium, thorium, and other radioactive elements as well as mercury, and other heavy metals...
  29. Methyl Mercury Effect on Adolescent Development Renewal
    Philip W Davidson; Fiscal Year: 2013
    ..provided by applicant): This application is a competing renewal of Grant 5-R01ES008442 entitled "Methyl Mercury Effects on Adolescent Development...
  30. Role of Daf in Systemic Autoimmunity
    KENNETH MICHAEL POLLARD; Fiscal Year: 2012
    ..Induction of mercury-induced autoimmunity (HgIA) in B10.S mice decreases Daf1 mRNA levels and cell surface expression on CD4 T cells...
  31. Influence of Dietary Fish and mercury Exposure on Brain health and Dementia
    Martha Clare Morris; Fiscal Year: 2013
    ..clinical-neuropathological study, the Memory and Aging Project (MAP) to examine whether brain levels of mercury (Hg) and selenium (Se) are related to brain neuropathology (A[unreadable], neurofibrillary tangles, cerebral ..
  32. Climate impact on coastal ecosystem methylmercury: human exposure implications
    Celia Y Chen; Fiscal Year: 2013
    DESCRIPTION (provided by applicant) Mercury (Hg) is the third most important contaminant on the CERCLA Priority List of Hazardous Substances (2011) and its organic and toxic form, methyl mercury (MeHg), is a potent toxin with human ..
  33. Toxic Metals in the Northeast: From Biological To Environmental Implications
    Bruce A Stanton; Fiscal Year: 2013
    ..Research Program Project on toxic metals is to understand the human health impact of exposure to arsenic and mercury from environmental and anthropogenic sources...
  34. Trace element levels and risk of stroke
    Leslie Ain McClure; Fiscal Year: 2013
    ..The proposed study will focus on arsenic, cadmium, mercury, magnesium and selenium...
  35. Role of CD97 in Xenobiotic-Induced Autoimmunity
    KENNETH MICHAEL POLLARD; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Xenobiotics such as silica and mercury are associated with systemic autoimmunity in humans and mice...
  36. Structure Determination of Membrane Proteins in Phospholipid Bilyaers
    Stanley J Opella; Fiscal Year: 2013
    ..The second goal is to apply the method for structure determination to the mercury transport membrane proteins of the bacterial mercury detoxification system...
  37. Patient-oriented Research in Maternal Perinatal Overnutrition and Child Adiposity
    Emily Oken; Fiscal Year: 2013
    ..randomized trial of breastfeeding intervention;an ongoing NIEHS-funded R01 of maternal prenatal fish consumption, mercury exposure, and child development at age 7 years;and a CDC-funded project to develop an electronic medical record-..
  38. Influence of Innate Immunity on Xenobiotic-Induced Systemic Autoimmunity
    KENNETH MICHAEL POLLARD; Fiscal Year: 2013
    ..for endosomal toll-like receptors and/or UNC93B1 providing a unifying mechanism in idiopathic, pristane- and mercury-induced autoimmunity...
  39. Development and Validation of a Novel In Vivo Neutron Activation Analysis Technol
    Linda H Nie; Fiscal Year: 2013
    ..Mn exposure, the mechanism of the toxicity of Mn, and the interaction of Mn with other metals (such as lead and mercury) are unknown and therefore deserve further investigation...
  40. Confocal enhanced episcopic fluorescent image capture (EFIC)
    Cecilia W Lo; Fiscal Year: 2012
    ..generation EFIC imaging system, surface fluorescence is captured with epifluorescence imaging using standard mercury illumination...
  41. Childhood health disparities: exploration of prenatal exposures in primary teeth
    Andrea E Cassidy-Bushrow; Fiscal Year: 2013
    ..250 naturally shed primary teeth (230 unique children) will be collected and 5 metals (lead, cadmium, manganese, mercury, arsenic) will be measured with LA-ICP-MS...
  42. Summer Research and Training Program in Environmental Health Sciences
    F Peter Guengerich; Fiscal Year: 2012
    ..from chemical agents, and mechanisms of neurological and renal damage induced by metals (especially manganese and mercury)...
  43. Mechanisms of methylmercury toxicity in neural development
    Matthew D Rand; Fiscal Year: 2011
    ..S. having blood mercury levels at or above the reference dose set by the EPA...
  44. Cytokines, PUFA Tissue Concentrations and Treatment Selection in Antenatal MMD
    WILLIAM HENRY CORYELL; Fiscal Year: 2012
    ..PUFA deficits in the mother but access to adequate omega-3 PUFAs but fish intake is limited due to concerns over mercury levels...
  45. Development of Novel Genetic Tools for Metabolic Selection in Yersinia Pestis
    Deborah Anderson; Fiscal Year: 2009
    ..Plasmid borne resistance to divalent metal ions, for example mercury or copper, has been studied in both Gram negative and Gram positive bacteria and is well characterized...
  46. A Wireless, Passive Dosimeter for Tracking Mercury Vapor Exposure
    Keat Ghee Ong; Fiscal Year: 2010
    ..based on a magnetoelastic sensor is proposed for tracking personal exposure to toxic gaseous chemicals such as mercury vapor...
  47. Mercury exposure from fish consumption in subsistence fishers in rural Oklahoma
    Laurel A Schaider; Fiscal Year: 2012
    ..Americans, Hispanics, and Micronesians) and recreational anglers in northeastern Oklahoma are exposed to elevated mercury levels resulting from subsistence fishing practices...
  48. Improved Noise Attenuation Foam for In the Ear Hearing and Noise Devices
    William Parish; Fiscal Year: 2011
    ..The foam structures will be measured using mercury intrusion porosimetry, x-ray micro CT scanning, and microscopy. 3...
  49. ADMINISTRATIVE CORE, OVERALL APPROACH
    James E K Hildreth; Fiscal Year: 2011
    ..clinical research by MMC investigators linked to essential functions and administrative services (Research Point, MeRCury) 2...
  50. Phytostabilization and Retirement of Mercury from Wet Ecosystems
    Mark P Elless; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Because environmental mercury poses significant challenges to global public health, reducing mercury levels in air, soil, and water is an international priority...
  51. Novel Chelators for Highly Efficient Removal of Toxic Heavy Metals in Humans
    Charles Timchalk; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Exposure to toxic metals like cadmium (Cd), lead (Pb), mercury (Hg), chromate (CrO42-), arsenite (As) (III), and arsenate (AsO43-) are known to induce various diseases that are detrimental to human ..
  52. Activated Carbon as a Multifunctional Amendment to Treat PCBs and Mercury
    Richard G Luthy; Fiscal Year: 2010
    ..AC) amendment as a multifunctional, in-situ sediment remediation technique to reduce the bioavailability of both mercury (Hg) and polychlorinated biphenyls (PCBs) at contaminated sediment sites...
  53. MERCURY AND REPRODUCTIVE HEALTH IN WOMEN DENTISTS
    David Savitz; Fiscal Year: 1992
    ..Of particular concern in dentistry is the chronic low dose exposure to mercury vapor, occurring through the use of mercury in amalgam restorations...
  54. Resource for NMR Molecular Imaging of Proteins
    Stanley J Opella; Fiscal Year: 2013
    ..The Central Collaborations include structure determinations of the viroporins Vpu from HIV-1 and p7 from HCV, mercury transport membrane proteins with two, three, and four trans-membrane helices, filamentous bacteriophage coat ..
  55. AMALGAM RESTORATIONS AND PREGNANCY OUTCOMES
    Richard Mitchell; Fiscal Year: 1993
    A small amount of mercury vapor is released from dental amalgam restorations during mastication. This mercury can potentially influence pregnancy outcomes...
  56. Membrane Protein Structures in Phospholipid Bilayers by Solid State NMR
    STANLEY OPELLA; Fiscal Year: 2009
    ..develop solid-state NMR of aligned samples and to apply this approach to determine the structure of a family of mercury transport membrane proteins with two, three, and four trans-membrane helices...
  57. Catalytic DNA Biosensor for Toxic Metal Ions
    Yi Lu; Fiscal Year: 2009
    ..by applicant): Cost-effective catalytic DNA biosensors for heavy metal ions such as lead(II), uranium(VI), mercury(II), and cadmium(II) will be developed...
  58. MERCURY RESISTANCE IN STAPHYLOCOCCUS AUREUS
    RICHARD LADDAGA; Fiscal Year: 1992
    ..One of these resistance determinants is the mercury resistance determinant (mer operon) contained on the S. aureus plasmid pI258...
  59. Children's Environmental Health &Disease Prevention Research Center at Dartmouth
    MARGARET RITA KARAGAS; Fiscal Year: 2012
    ..g. cadmium and mercury.) on fetal development and maternal/infant immune function...
  60. Mississippi State Chemical Laboratory for MFRPS Lab Accreditation
    Ashli Brown; Fiscal Year: 2013
    ..extraction and analysis of pesticides in manufactured jams/jellies and edible ice, as well as analysis of metals (mercury, lead, copper, and arsenic) in edible ice...
  61. EVALUATION OF MERCURY RELEASE FROM DENTAL AMALGAMS
    Toru Okabe; Fiscal Year: 2003
    ..goal of this application is to determine the mechanism by which changes in the formulation of the alloy reduce mercury (Hg) release from dental amalgam...
  62. DENTAL AMALGAMS AND NEUROPSYCHOLOGICAL FUNCTION
    Pam Factor Litvak; Fiscal Year: 1999
    DESCRIPTION: There is considerable evidence that some mercury from "silver fillings" distributes to body tissues, particularly the brain...
  63. DISSOLUTION OF MERCURY FROM DENTAL AMALGAMS
    Miroslav Marek; Fiscal Year: 2001
    Dental amalgam remains the most common direct filling material for restoration of tooth structure. The presence of mercury in a material used in the oral cavity has raised some concerns...
  64. METALLOTHIONEIN, MERCURY AND MONOCYTE ACTIVATION
    RUDOLFS ZALUPS; Fiscal Year: 2006
    b>Mercury (Hg) is a widely disseminated toxicant found in various occupational, environmental and domestic settings. It exerts a wide range of cellular toxicities in various human tissues and organs...
  65. HEALTH EFFECTS OF DENTAL AMALGAMS IN CHILDREN
    Sonja McKinlay; Fiscal Year: 2005
    ..since its introduction 150 years ago, but-until recently it has been generally assumed that the exposure to mercury from dental amalgam is limited to the acute placement phase...
  66. Catalytic DNA Biosensor for Toxic Metal Ions
    Yi Lu; Fiscal Year: 2005
    ..for on-site, real-time, and cost-effective detection and quantification of multiple heavy metal ions, such as mercury, cadmium and lead, simultaneously will be explored...
  67. Portable Analyzer for On-site Monitoring of Worker Exposure to Toxic Metals
    Charles Timchalk; Fiscal Year: 2007
    ..Large numbers of industrial workers are regularly exposed to toxic heavy metals like cadmium (Cd), lead (Pb), and mercury (Hg), which are known to induce various diseases that are detrimental to human health...