bismuth

Summary

Summary: A metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.

Top Publications

  1. ncbi An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles
    Oded Rabin
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Mater 5:118-22. 2006
  2. ncbi Moxifloxacin-containing triple therapy versus bismuth-containing quadruple therapy for second-line treatment of Helicobacter pylori infection: a meta-analysis
    Cheng Wu
    Department of Digestive Endoscopy, Division of Southern Building, Chinese PLA General Hospital, Beijing, China
    Helicobacter 16:131-8. 2011
  3. pmc Microbial methylation of metalloids: arsenic, antimony, and bismuth
    Ronald Bentley
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Microbiol Mol Biol Rev 66:250-71. 2002
  4. ncbi Exfoliation and characterization of bismuth telluride atomic quintuples and quasi-two-dimensional crystals
    Desalegne Teweldebrhan
    Department of Electrical Engineering and Materials Science, Bourns College of Engineering, University of California Riverside, Riverside, California 92521, USA
    Nano Lett 10:1209-18. 2010
  5. ncbi Bismuth-containing quadruple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate in Korea
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Helicobacter 15:38-45. 2010
  6. pmc Standard triple, bismuth pectin quadruple and sequential therapies for Helicobacter pylori eradication
    Xiao Zhong Gao
    Division of Gastroenterology, Weihai Municipal Hospital, Weihai 264200, Shandong Province, China
    World J Gastroenterol 16:4357-62. 2010
  7. ncbi Efficacy and safety of single-triple capsules of bismuth biskalcitrate, metronidazole and tetracycline, given with omeprazole, for the eradication of Helicobacter pylori: an international multicentre study
    C O'Morain
    Department of Gastroenterology, Adelaide and Health Hospital, Tallaght, Dublin, Ireland
    Aliment Pharmacol Ther 17:415-20. 2003
  8. ncbi Electrodeposited bismuth telluride nanowire arrays with uniform growth fronts
    Lynn Trahey
    Department of Chemistry, University of California, Berkeley, California 94720, USA
    Nano Lett 7:2535-9. 2007
  9. ncbi Methylated bismuth, but not bismuth citrate or bismuth glutathione, induces cyto- and genotoxic effects in human cells in vitro
    U von Recklinghausen
    Institute of Hygiene and Occupational Health, University Hospital, Hufelandstrasse 55, 45122 Essen, Germany
    Chem Res Toxicol 21:1219-28. 2008
  10. ncbi Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis
    Richard J Saad
    Department of Medicine, Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Ann Arbor, MI 48109, USA
    Am J Gastroenterol 101:488-96. 2006

Detail Information

Publications357 found, 100 shown here

  1. ncbi An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles
    Oded Rabin
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Nat Mater 5:118-22. 2006
    ..These nanoparticles and their bioconjugates are expected to become an important adjunct to in vivo imaging of molecular targets and pathological conditions...
  2. ncbi Moxifloxacin-containing triple therapy versus bismuth-containing quadruple therapy for second-line treatment of Helicobacter pylori infection: a meta-analysis
    Cheng Wu
    Department of Digestive Endoscopy, Division of Southern Building, Chinese PLA General Hospital, Beijing, China
    Helicobacter 16:131-8. 2011
    ..Moxifloxacin-containing triple therapy has been suggested as an alternative second-line therapy for Helicobacter pylori infection...
  3. pmc Microbial methylation of metalloids: arsenic, antimony, and bismuth
    Ronald Bentley
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Microbiol Mol Biol Rev 66:250-71. 2002
    ..The other metalloid elements of the periodic table group 15, antimony and bismuth, also undergo biomethylation to some extent...
  4. ncbi Exfoliation and characterization of bismuth telluride atomic quintuples and quasi-two-dimensional crystals
    Desalegne Teweldebrhan
    Department of Electrical Engineering and Materials Science, Bourns College of Engineering, University of California Riverside, Riverside, California 92521, USA
    Nano Lett 10:1209-18. 2010
    b>Bismuth telluride (Bi(2)Te(3)) and its alloys are the best bulk thermoelectric materials known today. In addition, stacked quasi-two-dimensional (2D) layers of Bi(2)Te(3) were recently identified as promising topological insulators...
  5. ncbi Bismuth-containing quadruple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate in Korea
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Helicobacter 15:38-45. 2010
    ..The aim of this study was to evaluate the efficacy of bismuth-containing quadruple therapy as second-line treatment for H. pylori infection based on treatment duration.
  6. pmc Standard triple, bismuth pectin quadruple and sequential therapies for Helicobacter pylori eradication
    Xiao Zhong Gao
    Division of Gastroenterology, Weihai Municipal Hospital, Weihai 264200, Shandong Province, China
    World J Gastroenterol 16:4357-62. 2010
    To compare the effectiveness of standard triple, bismuth pectin quadruple and sequential therapies for Helicobacter pylori (H. pylori) eradication in a randomized, double-blinded, comparative clinical trial in China.
  7. ncbi Efficacy and safety of single-triple capsules of bismuth biskalcitrate, metronidazole and tetracycline, given with omeprazole, for the eradication of Helicobacter pylori: an international multicentre study
    C O'Morain
    Department of Gastroenterology, Adelaide and Health Hospital, Tallaght, Dublin, Ireland
    Aliment Pharmacol Ther 17:415-20. 2003
    The high prevalence of Helicobacter pylori resistance to metronidazole demands treatments more effective than standard bismuth-based triple therapy against these strains.
  8. ncbi Electrodeposited bismuth telluride nanowire arrays with uniform growth fronts
    Lynn Trahey
    Department of Chemistry, University of California, Berkeley, California 94720, USA
    Nano Lett 7:2535-9. 2007
    b>Bismuth telluride (Bi2Te3) nanowires were deposited into porous alumina templates with 35 nm diameter pores by a pulsed-potential electrodeposition method...
  9. ncbi Methylated bismuth, but not bismuth citrate or bismuth glutathione, induces cyto- and genotoxic effects in human cells in vitro
    U von Recklinghausen
    Institute of Hygiene and Occupational Health, University Hospital, Hufelandstrasse 55, 45122 Essen, Germany
    Chem Res Toxicol 21:1219-28. 2008
    b>Bismuth compounds are widely used in industrial processes and products...
  10. ncbi Levofloxacin-based triple therapy versus bismuth-based quadruple therapy for persistent Helicobacter pylori infection: a meta-analysis
    Richard J Saad
    Department of Medicine, Division of Gastroenterology, University of Michigan Medical Center, 3912 Taubman Center, Ann Arbor, MI 48109, USA
    Am J Gastroenterol 101:488-96. 2006
    Levofloxacin-based triple therapy has been suggested as an alternative salvage therapy to bismuth-based quadruple therapy for persistent Helicobacter pylori (H. pylori) infection.
  11. pmc Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins
    Ekaterina Dadachova
    Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS Med 3:e427. 2006
    ..The aim of this proof-of-principle study was to demonstrate the efficacy of a therapeutic strategy of targeting and eliminating HIV-1-infected cells with radiolabeled antibodies specific to viral proteins in vitro and in vivo...
  12. ncbi A systematic comparison of triple therapies for treatment of Helicobacter pylori infection with proton pump inhibitor/ ranitidine bismuth citrate plus clarithromycin and either amoxicillin or a nitroimidazole
    M J Janssen
    Department of Gastroenterology and Hepatology, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Aliment Pharmacol Ther 15:613-24. 2001
    Triple therapies with proton pump inhibitor/ranitidine bismuth citrate (RBC), clarithromycin (C) and either amoxicillin (A) or a nitroimidazole (I) are widely accepted as treatment for Helicobacter pylori infection...
  13. ncbi Moxifloxacine plus amoxicillin and ranitidine bismuth citrate or esomeprazole triple therapies for Helicobacter pylori infection
    Zeki Mesut Yalin Kilic
    Department of Gastroenterology, Turkiye Yuksek Ihtisas Hospital, Sihhiye, Ankara, Turkey
    Dig Dis Sci 53:3133-7. 2008
    ..patients were randomized into four groups to receive one of the following 14-day treatments: ranitidine bismuth citrate (RBC) 400 mg b.d. plus amoxicillin 1 g b.d. and clarithromycin 500 mg b.d...
  14. pmc Sequential cytarabine and alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia
    Todd L Rosenblat
    Department of Medicine and the Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Clin Cancer Res 16:5303-11. 2010
    ..antibody without the nonspecific cytotoxicity associated with β-emitters, the α-particle-emitting radionuclide bismuth-213 ((213)Bi) was conjugated to lintuzumab...
  15. ncbi Role of Hpn and NixA of Helicobacter pylori in susceptibility and resistance to bismuth and other metal ions
    H L Mobley
    Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore 21201, USA
    Helicobacter 4:162-9. 1999
    ..We tested the hypothesis that Hpn and NixA govern susceptibility to metal ions in H. pylori...
  16. ncbi Effect of bismuth oxide radioopacifier content on the material properties of an endodontic Portland cement-based (MTA-like) system
    Kristian S Coomaraswamy
    Pediatric Dentistry, School of Dentistry, University of Birmingham, St Chad s Queensway, Birmingham, United Kingdom
    J Endod 33:295-8. 2007
    The effect of bismuth oxide (Bi2O3) radioopacifier addition on the material properties of an endodontic Portland cement-based system were investigated...
  17. ncbi Intravesical alpha-radioimmunotherapy with 213Bi-anti-EGFR-mAb defeats human bladder carcinoma in xenografted nude mice
    Birgit Pfost
    Department of Nuclear Medicine, Technische Universitat Munchen, Munich, Germany
    J Nucl Med 50:1700-8. 2009
    ....
  18. pmc Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model
    John M Pagel
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Blood 118:703-11. 2011
    ..These data suggest that anti-CD45 PRIT using an α-emitting radionuclide may be highly effective and minimally toxic for treatment of acute myeloid leukemia...
  19. ncbi Effects of simvastain and enamel matrix derivative on Portland cement with bismuth oxide-induced growth and odontoblastic differentiation in human dental pulp cells
    So Youn Lee
    Department of Maxillofacial Tissue Regeneration, School of Dentistry and Institute of Oral Biology, Kyung Hee University, Seoul, Republic of Korea
    J Endod 38:405-10. 2012
    We previously reported that bismuth oxide containing Portland cement (BPC) showed similar biocompatibility to Portland cement (PC) in periodontal ligament cells...
  20. ncbi Intralesional targeted alpha therapy for metastatic melanoma
    Barry J Allen
    Centre for Experimental Radiation Oncology, St George Hospital, Kogarah, NSW 2217, Australia
    Cancer Biol Ther 4:1318-24. 2005
    ..This paper reports the development and application of intralesional targeted alpha therapy (TAT) for melanoma, being the first part of a program to establish a new systemic therapy...
  21. ncbi Exposure of cultured human proximal tubular cells to cadmium, mercury, zinc and bismuth: toxicity and metallothionein induction
    V Rodilla
    Department of Medicine, University of Aberdeen, UK
    Chem Biol Interact 115:71-83. 1998
    ..The results showed that bismuth was not toxic even at the highest dose (100 microM) used, while zinc, cadmium and mercury exhibited varying ..
  22. ncbi Bismuth nanoparticles for phenolic compounds biosensing application
    Carmen C Mayorga-Martinez
    Nanobioelectronics and Biosensors Group, CIN2 ICN CSIC, Catalan Institute of Nanotechnology, Campus de la UAB, 08193 Bellaterra, Barcelona, Spain
    Biosens Bioelectron 40:57-62. 2013
    ..A mediator-free amperometric biosensor for phenolic compounds detection based on the combination of bismuth nanoparticles (BiNPs) and Tyr for phenol detections will be hereby reported...
  23. ncbi [Efficacy of a multistep strategy for Helicobacter pylori eradication: quadruple therapy with omeprazole, metronidazole, tetracycline and bismuth after failure of a combination of omeprazole, clarithromycin and amoxycillin]
    J M Baena Diez
    Area Básica de Salud Dr Carles Ribas Barcelona
    Med Clin (Barc) 115:617-9. 2000
    ..To evaluate the efficacy of a multistep strategy for Helicobacter pylori (HP) eradication...
  24. ncbi Bioinorganic chemistry of bismuth and antimony: target sites of metallodrugs
    Ruiguang Ge
    Department of Chemistry and Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam, Hong Kong, PR China
    Acc Chem Res 40:267-74. 2007
    The biocoordination chemistry of antimony and bismuth has been extensively investigated due to the historical use of these metals in medicine...
  25. ncbi Inhibition of urease by bismuth(III): implications for the mechanism of action of bismuth drugs
    Li Zhang
    Department of Chemistry and Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam, Hong Kong, PR China
    Biometals 19:503-11. 2006
    b>Bismuth compounds are widely used for the treatment of peptic ulcers and Helicobacter pylori infections. It has been suggested that enzyme inhibition plays an important role in the antibacterial activity of bismuth towards this bacterium...
  26. ncbi Bismuth modified carbon-based electrodes for the determination of selected neonicotinoid insecticides
    Valéria Guzsvány
    Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg D Obradovica 3, 21000 Novi Sad, Serbia
    Molecules 16:4451-66. 2011
    Two types of bismuth modified electrodes, a bismuth-film modified glassy carbon (BiF-GCE) and a bismuth bulk modified carbon paste, were applied for the determination of selected nitroguanidine neonicotinoid insecticides...
  27. ncbi A comparison between sequential therapy and a modified bismuth-based quadruple therapy for Helicobacter pylori eradication in Iran: a randomized clinical trial
    Hafez Fakheri
    Department of Gastroenterology, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran
    Helicobacter 17:43-8. 2012
    ..So we designed a study to compare a sequential regimen with a bismuth-based quadruple therapy that contains a short course of furazolidone, in Iran.
  28. ncbi Parallel on-line detection of a methylbismuth species by hyphenated GC/EI-MS/ICP-MS technique as evidence for bismuth methylation by human hepatic cells
    Markus Hollmann
    Institute of Environmental Analytical Chemistry, University of Duisburg Essen, Universitaetsstrasse 3 5, Essen, Germany
    Metallomics 2:52-6. 2010
    ..HepG2 cells were incubated with colloidal bismuth subcitrate, bismuth cysteine and bismuth glutathione, respectively for a period of 24 h...
  29. ncbi High-linear energy transfer (LET) alpha versus low-LET beta emitters in radioimmunotherapy of solid tumors: therapeutic efficacy and dose-limiting toxicity of 213Bi- versus 90Y-labeled CO17-1A Fab' fragments in a human colonic cancer model
    T M Behr
    Department of Nuclear Medicine, Georg August University, Gottingen, Germany
    Cancer Res 59:2635-43. 1999
    ..Due to its short physical half-life, 213Bi appears to be especially suitable for use in conjunction with fast-clearing fragments...
  30. ncbi Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source
    David Touboul
    Institut de Chimie des Substances Naturelles, CNRS, Gif sur Yvette Cedex, France
    J Am Soc Mass Spectrom 16:1608-18. 2005
    A new liquid metal ion gun (LMIG) filled with bismuth has been fitted to a time-of-flight-secondary ion mass spectrometer (TOF-SIMS). This source provides beams of Bi(n)q+ clusters with n = 1-7 and q = 1 and 2...
  31. ncbi Targeted alpha particle immunotherapy for myeloid leukemia
    Joseph G Jurcic
    Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Medical College of Cornell University, New York, NY 10021, USA
    Blood 100:1233-9. 2002
    ..This study demonstrates the safety, feasibility, and antileukemic effects of (213)Bi-HuM195, and it is the first proof-of-concept for systemic targeted alpha particle immunotherapy in humans...
  32. ncbi Pretargeting radioimmunotherapy of a murine model of adult T-cell leukemia with the alpha-emitting radionuclide, bismuth 213
    Meili Zhang
    Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 100:208-16. 2002
    ..T-cell leukemia with an anti-Tac antibody-streptavidin (HAT-SA) conjugate, which recognizes CD25, followed by bismuth 213 ((213)Bi)-1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)- biotin...
  33. ncbi Systematic review: Antacids, H2-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia
    P Moayyedi
    Gastroenterology Unit, City Hospital NHS Trust, Birmingham, UK
    Aliment Pharmacol Ther 17:1215-27. 2003
    Evidence for the effectiveness of antacids, histamine-2 receptor antagonists, bismuth salts, sucralfate and prokinetic therapy in non-ulcer dyspepsia is conflicting.
  34. ncbi In vitro evaluation of 213Bi-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage
    Katia Vandenbulcke
    Department of Radiopharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Gent, Belgium
    Eur J Nucl Med Mol Imaging 30:1357-64. 2003
    ..Long-term toxicity on healthy B and T lymphocytes was systematically higher for the alpha emitter (RBE=5 to 2)...
  35. ncbi Surfactant-free synthesis of hyperbranched monoclinic bismuth vanadate and its applications in photocatalysis, gas sensing, and lithium-ion batteries
    Yu Zhao
    Department of Nanomaterials and Nanochemistry, Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui, P R China
    Chemistry 14:1601-6. 2008
    ....
  36. ncbi Bismuth telluride (Bi2Te3) nanowires: synthesis by cyclic electrodeposition/stripping, thinning by electrooxidation, and electrical power generation
    E J Menke
    Institute For Surface and Interface Science and Department of Chemistry, University of California, Irvine, California 92679 2025, USA
    Langmuir 22:10564-74. 2006
    ..onto these nuclei using a cyclic electrodeposition-stripping scheme that involved the electrodeposition of bismuth-rich Bi2Te3 on a negative-going voltammetric scan (to -0...
  37. ncbi Atomically thick bismuth selenide freestanding single layers achieving enhanced thermoelectric energy harvesting
    Yongfu Sun
    Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230026, PR China
    J Am Chem Soc 134:20294-7. 2012
    ..This work develops a facile strategy for synthesizing atomically thick single layers and demonstrates their superior ability to optimize the thermoelectric energy harvesting...
  38. ncbi Autometallographic tracing of bismuth in human brain autopsies
    M Stoltenberg
    Department of Neurobiology, Institute of Anatomy, University of Aarhus, Denmark
    J Neuropathol Exp Neurol 60:705-10. 2001
    For decades, drugs containing bismuth have been used to treat gastrointestinal disorders...
  39. ncbi Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study
    Katia Vandenbulcke
    Department of Radiopharmacy, Ghent University, Belgium
    Nucl Med Commun 25:1131-6. 2004
    ..The development of RIT with alpha emitters is attractive because of the high linear energy transfer (LET) and short path length, allowing higher tumour cell kill and lower toxicity to healthy tissues...
  40. ncbi In vitro and preclinical targeted alpha therapy of human prostate cancer with Bi-213 labeled J591 antibody against the prostate specific membrane antigen
    Y Li
    Centre for Experimental Radiation Oncology, Cancer Care Centre, St George Hospital, Kogarah, NSW, Australia
    Prostate Cancer Prostatic Dis 5:36-46. 2002
    ..Because of its in vitro cytotoxicity and these anti-proliferative properties in vivo, the (213)Bi-J591 conjugate has considerable potential as a new therapeutic agent for the treatment of prostate cancer...
  41. ncbi Flow injection-hydride generation atomic absorption spectrometric determination of selenium, arsenic and bismuth
    Yanlin Zhang
    NanoScience and Sensor Technology Research Group, School of Applied Sciences and Engineering, Monash University Gippsland Campus, Churchill, Victoria 3842, Australia
    Talanta 76:724-30. 2008
    ..for rapid and reliable hydride generation atomic absorption spectrometric determination of selenium, arsenic and bismuth. The system, which composed of one peristaltic pump and one four channel solenoid valve, used water as the ..
  42. ncbi The effect of curing conditions on the physical properties of tricalcium silicate cement for use as a dental biomaterial
    L M Formosa
    Department of Metallurgy and Materials Engineering, Faculty of Engineering, University of Malta, Msida, Malta
    Int Endod J 45:326-36. 2012
    ..To investigate the physical properties of tricalcium silicate (TCS) with and without the addition of a radiopacifier and compare them with that of Portland cement (PC) and radiopaque PC in an mineral trioxide aggregate-like system...
  43. ncbi A new class of room-temperature multiferroic thin films with bismuth-based supercell structure
    Aiping Chen
    Department of Electrical and Computer Engineering, Texas A and M University, College Station, TX 77843 3128, USA
    Adv Mater 25:1028-32. 2013
    ..These results open up a new avenue for exploring room-temperature single-phase multiferroic thin films by controlling the phase mixing of two perovskite BiRO(3) (R = Cr, Mn, Fe, Co, Ni) materials...
  44. ncbi The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-controlled triple-blind study
    Ahmad Shavakhi
    Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
    Helicobacter 18:280-4. 2013
    Evidence has shown benefits of single-strain probiotics for Helicobacter pylori eradication. We investigated the effects of adding a multistrain probiotic compound on bismuth-containing quadruple therapy for H. pylori infection.
  45. ncbi Synthesis, characterization and enhanced thermoelectric performance of structurally ordered cable-like novel polyaniline-bismuth telluride nanocomposite
    Krishanu Chatterjee
    Department of Physics, Bengal Engineering and Science University, Shibpur, Howrah 711103, West Bengal, India
    Nanotechnology 24:215703. 2013
    b>Bismuth telluride (Bi₂Te₃) nanorods and polyaniline (PANI) nanoparticles have been synthesized by employing solvothermal and chemical oxidative processes, respectively...
  46. ncbi Vacancy associates promoting solar-driven photocatalytic activity of ultrathin bismuth oxychloride nanosheets
    Meili Guan
    Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui, 230026, PR China
    J Am Chem Soc 135:10411-7. 2013
    ....
  47. ncbi Ten-day Quadruple therapy comprising proton-pump inhibitor, bismuth, tetracycline, and levofloxacin achieves a high eradication rate for Helicobacter pylori infection after failure of sequential therapy
    Ping I Hsu
    Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital and National Yang Ming University, Kaohsiung, Taiwan
    Helicobacter 19:74-9. 2014
    ..However, it fails in 5-24% of infected subjects, and the recommended levofloxacin-containing triple rescue therapy only achieves a 77% eradication rate after failure of sequential therapy...
  48. ncbi Ethanol-phosphotungstic acid and bismuth staining of spermatid nucleoli in mouse spermiogenesis
    I K Takeuchi
    Department of Embryology, Institute for Developmental Research, Aichi Prefectural Colony, Japan
    J Struct Biol 103:104-12. 1990
    ..of developing mouse spermatids were examined with ethanol-phosphotungstic acid (E-PTA) staining, and also with bismuth staining following formaldehyde fixation (FA-Bi staining) and glutaraldehyde fixation (GA-Bi staining)...
  49. ncbi Revealing bismuth oxide hollow nanoparticle formation by the Kirkendall effect
    Kai Yang Niu
    Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States
    Nano Lett 13:5715-9. 2013
    We study the formation of bismuth oxide hollow nanoparticles by the Kirkendall effect using liquid cell transmission electron microscopy (TEM). Rich dynamics of bismuth diffusion through the bismuth oxide shell have been captured in situ...
  50. ncbi Nanoparticles of the novel coordination polymer KBi(H2O)2[Fe(CN)6]·H2O as a potential contrast agent for computed tomography
    Vindya S Perera
    Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44240, USA
    Inorg Chem 50:7910-2. 2011
    An aqueous synthetic procedure for preparing nanoparticles of the novel potassium bismuth ferrocyanide coordination polymer KBi(H(2)O)(2)[Fe(CN)(6)]·H(2)O is reported...
  51. ncbi Retreatment of Helicobacter pylori infection after initial treatment failure
    D J Kearney
    Gastroenterology Section, University of Washington, VA Puget Sound Health Care System, Seattle, USA
    Am J Gastroenterol 96:1335-9. 2001
    ..pylori infection remains limited. The existing data support the use of bismuth-based quadruple therapy or ranitidine bismuth citrate (RBC)-based triple therapy as the preferred agents after ..
  52. ncbi Preparation and testing of bevacizumab radioimmunoconjugates with Bismuth-213 and Bismuth-205/Bismuth-206
    Syed M Abbas Rizvi
    Centre for Experimental Radiation Oncology CERO, Division of Cancer Services, St George Hospital, Kogarah, New South Wales, Australia
    Cancer Biol Ther 7:1547-54. 2008
    ..The in vitro and in vivo stability tests were carried out using Bi-213 and long half-life Bismuth isotope (Bi-205/Bi-206) for pharmacokinetics...
  53. ncbi Bismuth film electrodes for the study of metal thiolate complexation: an alternative to mercury electrodes
    Arístides Alberich
    Departament de Quimica Analitica, Facultat de Quimica, Universitat de Barcelona, Marti i Franques 1 11, E 08028 Barcelona, Spain
    Talanta 78:1017-22. 2009
    A comparative study of the usual static mercury drop electrode (SMDE) and the bismuth film electrode (BiFE) as applied to the analysis of metal complexation by thiol-rich peptides is done...
  54. ncbi Bismuth autometallography: protocol, specificity, and differentiation
    G Danscher
    Department of Neurobiology, Institute of Anatomy, University of Aarhus, Denmark
    J Histochem Cytochem 48:1503-10. 2000
    We provide a detailed protocol of the autometallographic bismuth technique and evaluate the specificity of the technique...
  55. ncbi Synthesis and photocatalytic properties of bismuth titanate with different structures via oxidant peroxo method (OPM)
    André E Nogueira
    LIEC Laboratório Interdisciplinar de Eletroquímica e Cerâmica, Departamento de Quimica, UFSCar Universidade Federal de São Carlos, Rod Washington Luis Km 235, CP 676 São Carlos, SP 13565 905, Brazil Electronic address
    J Colloid Interface Sci 415:89-94. 2014
    b>Bismuth titanate (Bi4Ti3O12 and Bi12TiO20) powders were synthesized by the Oxidant Peroxide Method (OPM), and the effect of temperatures on physical and chemical properties of particles was investigated...
  56. ncbi Efficient photocatalytic removal of NO in indoor air with hierarchical bismuth oxybromide nanoplate microspheres under visible light
    Zhihui Ai
    Department of Civil and Structural Engineering, Research Center for Environmental Technology and Management, The Hong Kong Polytechnic University, Hong Kong, People s Republic of China
    Environ Sci Technol 43:4143-50. 2009
    In this study, hierarchical bismuth oxybromide (BiOBr) nanoplate microspheres were used to remove NO in indoor air under visible light irradiation...
  57. pmc Bismuth coating of non-tunneled haemodialysis catheters reduces bacterial colonization: a randomized controlled trial
    Ralf Schindler
    Department of Nephrology and Intensive Care Medicine, Charite Virchow Klinikum, Universitaetsmedizin zu Berlin, Berlin, Germany
    Nephrol Dial Transplant 25:2651-6. 2010
    ..Haemodialysis (HD) catheter-related blood stream infections are a major cause of morbidity and mortality in patients with acute and chronic renal failure...
  58. ncbi Salvage therapies after failure of Helicobacter pylori eradication with ranitidine bismuth citrate-based therapies
    F K Chan
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong
    Aliment Pharmacol Ther 14:91-5. 2000
    Salvage therapies after initial Helicobacter pylori eradication failure of ranitidine bismuth citrate (RBC)-based regimens remain undefined.
  59. ncbi The initialization and manipulation of quantum information stored in silicon by bismuth dopants
    Gavin W Morley
    London Centre for Nanotechnology, University College London, London WC1H 0AH, UK
    Nat Mater 9:725-9. 2010
    ..Heavier impurities such as bismuth in silicon (Si:Bi) could be used in conjunction with Si:P for quantum information proposals that require two ..
  60. ncbi Bismuth in medicine
    Hongzhe Sun
    Department of Chemistry, Open Laboratory of Chemical Biology, University of Hong Kong, Pokfulam Road, Hong Kong, P R China
    Met Ions Biol Syst 41:333-78. 2004
  61. pmc Efficacy of liposomal bismuth-ethanedithiol-loaded tobramycin after intratracheal administration in rats with pulmonary Pseudomonas aeruginosa infection
    Moayad Alhariri
    Novel Drug and Vaccine Delivery Systems Facility, Department of Chemistry and Biochemistry, Laurentian University, Sudbury, ON, Canada
    Antimicrob Agents Chemother 57:569-78. 2013
    ..and in the release of Pseudomonas aeruginosa virulence factors, as well as the in vivo antimicrobial activity of bismuth-ethanedithiol incorporated into a liposome-loaded tobramycin formulation (LipoBiEDT-TOB) administered to rats ..
  62. ncbi Preparation and characterization of bismuth oxide nanoparticles-multiwalled carbon nanotube composite for the development of horseradish peroxidase based H₂O₂ biosensor
    Arun Prakash Periasamy
    Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No 1, Section 3, Chung Hsiao East Road, Taipei 106, Taiwan, ROC
    Talanta 87:15-23. 2011
    In this work, preparation and characterization of a novel nanocomposite containing bismuth oxide (Bi(2)O(3)) nanoparticles and multiwalled carbon nanotubes (MWCNTs) was presented...
  63. ncbi A highly efficient bismuth salts-catalyzed route for the synthesis of α-aminophosphonates
    Antara Banik
    Department of Chemistry, The University of Texas Pan American, 1201 West University Drive, Edinburg, TX 78541, USA
    Molecules 15:8205-13. 2010
    ..amino phosphonates via one-pot solvent-free three component reactions of aldehydes, amines and phosphites catalyzed by bismuth salts has been investigated. Bismuth triflate is found to be the most effective catalyst for this reaction.
  64. ncbi Anti-Leishmanial activity of homo- and heteroleptic bismuth(III) carboxylates
    Philip C Andrews
    School of Chemistry, Monash University, Clayton, Melbourne, Victoria, Australia
    J Inorg Biochem 105:454-61. 2011
    b>Bismuth(III) complexes of NSAIDs (Non-Steroidal Anti Inflammatory Drugs) and substituted benzoic acids (o-methoxybenzoic acid, m-methoxybenzoic acid, o-nitrobenzoic acid, 3,5-diacetamidobenzoic acid, and 5-[(R/S)-2,3-dihydroxypropyl ..
  65. ncbi Second-line Helicobacter pylori eradication: a randomized comparison of 1-week or 2-week bismuth-containing quadruple therapy
    Jun Won Chung
    Department of Internal Medicine, Gil Medical Center, Gachon Graduate School of Medicine, Incheon, Korea
    Helicobacter 16:289-94. 2011
    ..b>Bismuth-based quadruple therapy is recommended as a second-line treatment, but the optimal duration of this treatment is ..
  66. pmc In vitro effect of lead, silver, tin, mercury, indium and bismuth on human sperm creatine kinase activity: a presumable mechanism for men infertility
    Mohammad Ali Ghaffari
    Cellular and Molecular Research Center and Physiology Research Center, Ahwaz Jundishapur University of Medical Sciences, Iran
    Iran Biomed J 15:38-43. 2011
    The aim of the present study was to investigate the in vitro effects of mercury (Hg+2), lead (Pb+2), silver (Ag+2), tin (Sn+2), bismuth (Bi+3) and indium (In+3) ions on sperm creatine kinase.
  67. ncbi Histochemical tracing of bismuth in testis from rats exposed intraperitoneally to bismuth subnitrate
    M Stoltenberg
    Department of Neurobiology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark
    Reprod Toxicol 14:65-71. 2000
    The histochemical silver amplification technique autometallography (AMG), was used to trace bismuth in the testis of Wistar rats injected intraperitoneally with bismuth subnitrate...
  68. ncbi Biomolecule-assisted synthesis of highly ordered snowflakelike structures of bismuth sulfide nanorods
    Qingyi Lu
    Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Am Chem Soc 126:54-5. 2004
    ..By controlling the molar ratio between bismuth nitrate and glutathione as well as the synthetic temperature, several kinds of Bi2S3 one-dimensional ..
  69. ncbi Is eradication of Helicobacter pylori with colloidal bismuth subcitrate quadruple therapy safe?
    R H Phillips
    Dept Clinical Biochemistry, School of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, UK
    Helicobacter 6:151-6. 2001
    ..Helicobacter pylori, quadruple 'rescue' therapy is often used which, in Europe, generally comprises colloidal bismuth subcitrate (CBS) based triple therapy and a proton pump inhibitor...
  70. ncbi Nanocrystallization of ferroelectric strontium bismuth vanadium niobate in lithium tetraborate glasses
    B Harihara Venkataraman
    Materials Research Centre, Indian Institute of Science, Bangalore, India
    J Nanosci Nanotechnol 5:2108-16. 2005
    ..Glass composites comprising vanadium doped strontium bismuth niobate nanocrystallites were obtained by controlled heat-treatment of the as-quenched glasses at 783 K for 6 h...
  71. pmc Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody
    J Schwartz
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Phys Med Biol 56:721-33. 2011
    ..Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of (225)Ac radioimmunotherapy...
  72. ncbi Ex vivo assessment of genotoxicity and cytotoxicity in murine fibroblasts exposed to white MTA or white Portland cement with 15% bismuth oxide
    E G Zeferino
    Endodontic Area, Center for Dental Research, São Leopoldo Mandic University, Campinas, Brazil
    Int Endod J 43:843-8. 2010
    To evaluate whether white mineral trioxide aggregate (MTA) or white Portland cement with 15% bismuth oxide were able to induce genetic damage and cellular death ex vivo.
  73. ncbi Comparative cellular catabolism and retention of astatine-, bismuth-, and lead-radiolabeled internalizing monoclonal antibody
    Z Yao
    Department of Nuclear Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, 10 Center Dr, Bethesda, MD 20892-1180, USA
    J Nucl Med 42:1538-44. 2001
    ..These catabolism differences may be important in the selection of alpha-radionuclides for radioimmunotherapy...
  74. ncbi Coordination of lapachol to bismuth(III) improves its anti-inflammatory and anti-angiogenic activities
    Gabrieli L Parrilha
    Departamento de Quimica, Instituto de Ciencias Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270 901, Brazil
    Biometals 25:55-62. 2012
    ..However, coordination to bismuth(III) could be an interesting strategy for improvement of lapachol's therapeutic properties.
  75. ncbi Chemical composition, radiopacity, and biocompatibility of Portland cement with bismuth oxide
    Yun Chan Hwang
    Department of Conservative Dentistry, School of Dentistry, Dental Science Research Institute, Chonnam National University, Gwangju, Korea
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:e96-102. 2009
    This study compared the chemical constitution, radiopacity, and biocompatibility of Portland cement containing bismuth oxide (experimental cement) with those of Portland cement and mineral trioxide aggregate (MTA).
  76. ncbi Furazolidone, amoxicillin and omeprazole with or without bismuth for eradication of Helicobacter pylori in peptic ulcer disease
    M R Ghadir
    Department of Gastroenterology, Qum University of Medical Sciences, Iran
    Turk J Gastroenterol 22:1-5. 2011
    ..The aim of this study was to compare quadruple and triple furazolidone-based regimens to achieve an economically affordable regimen with acceptable success rate and fewer side effects...
  77. ncbi Coordination of bismuth and lead in porphyrins: towards an in-situ generator for alpha-radiotherapy?
    Zakaria Halime
    Universite de Rennes1, Sciences Chimiques de Rennes, UMR CNRS 6226 I C M V, 35042 Rennes Cedex, France
    Biochimie 91:1318-20. 2009
    In order to investigate the possible coordination of both bismuth(III) and lead(II) by porphyrins for an application in alpha-radioimmunotherapy, several series of functionalized bismuth porphyrins have been synthesized and their ..
  78. ncbi CdTe nanocrystal-based electrochemical biosensor for the recognition of neutravidin by anodic stripping voltammetry at electrodeposited bismuth film
    Dan Du
    Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, PR China
    Biosens Bioelectron 24:869-74. 2008
    ..sensor for recognition of neutravidin, as a model protein, using anodic stripping voltammetry at electrodeposited bismuth film is presented...
  79. ncbi Bismuth heterocycles based on a diphenyl sulfone scaffold: synthesis and substituent effect on the antifungal activity against Saccharomyces cerevisiae
    Toshihiro Murafuji
    Graduate School of Medicine, Department of Chemistry, Faculty of Science, Yamaguchi University, Yamaguchi 753 8512, Japan
    Eur J Med Chem 46:519-25. 2011
    ..b>Bismuth carboxylate 7b derived from p-nitrobenzoic acid and 2e exhibited inhibition activity comparable to those of 2e ..
  80. ncbi Seven-day 'rescue' therapy after Helicobacter pylori treatment failure: omeprazole, bismuth, tetracycline and metronidazole vs. ranitidine bismuth citrate, tetracycline and metronidazole
    J P Gisbert
    Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
    Aliment Pharmacol Ther 13:1311-6. 1999
    ..A 'rescue' therapy with a quadruple combination of O, bismuth (B), tetracycline (T) and metronidazole (M) has been recommended.
  81. pmc A histidine-rich and cysteine-rich metal-binding domain at the C terminus of heat shock protein A from Helicobacter pylori: implication for nickel homeostasis and bismuth susceptibility
    Shujian Cun
    Department of Chemistry and the Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    J Biol Chem 283:15142-51. 2008
    ..binding of Bi(3+) to the protein altered its quaternary structure from a heptamer to a dimer, indicating that bismuth may interfere with the biological functions of HspA...
  82. pmc Furazolidone, amoxicillin, bismuth and rabeprazole quadruple rescue therapy for the eradication of Helicobacter pylori
    Hong Cheng
    Department of Gastroenterology, Peking University First Hospital, Beijing 100034, China
    World J Gastroenterol 15:860-4. 2009
    ..To compare the efficacy and side effect profiles of three furazolidone and amoxicillin-based quadruple rescue therapies for the eradication of Helicobacter pylori (H pylori)...
  83. ncbi Evaluation of the strength and radiopacity of Portland cement with varying additions of bismuth oxide
    E Saliba
    Department of Oral and Dental Science, Bristol Dental School, University of Bristol, Bristol, UK
    Int Endod J 42:322-8. 2009
    To study the effect of addition of various proportions of bismuth oxide on compressive strength and radiopacity of Portland cement.
  84. ncbi Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori
    Philip C Andrews
    School of Chemistry, Monash University, PO Box 23, Clayton, Melbourne, VIC 3800, Australia
    Dalton Trans 39:2861-8. 2010
    The formation of bismuth(III) complexes of carboxylates and benzoates derived from the 1 : 3 reaction of BiPh(3) with the common non-steroidal anti-inflammatory drugs (NSAIDs) ketoprofen, naproxen, ibuprofen, mefenamic acid, diflunisal, ..
  85. ncbi Renal epithelial gene expression profile and bismuth-induced resistance against cisplatin nephrotoxicity
    Berend T Leussink
    Toxicology Laboratory, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Hum Exp Toxicol 22:535-40. 2003
    ..Pretreatment with bismuth salts, used as pharmaceuticals to treat gastric disorders, has been demonstrated to reduce cisplatin-induced ..
  86. ncbi Bismuth-213 radioimmunotherapy with C595 anti-MUC1 monoclonal antibody in an ovarian cancer ascites model
    Emma Y Song
    Centre for Experimental Radiation Oncology, Cancer Care Centre, St George Hospital, Kogarah, UK
    Cancer Biol Ther 7:76-80. 2008
    ..The aim of this study was to investigate the effect of targeted alpha therapy (TAT) for the control of ascites in an OC ascites mouse model; the biodistribution of (213)Bi-C595 and its long term toxicity...
  87. ncbi A randomized trial of lansoprazole, amoxycillin, and clarithromycin versus lansoprazole, bismuth, metronidazole and tetracycline in the retreatment of patients failing initial Helicobacter pylori therapy
    N Magaret
    Department of Medicine, Sections of Gastroenterology, Oregon Health Sciences University, Portland, OR 97201, USA
    Dig Dis 19:174-8. 2001
    ..1,000 mg twice daily, and clarithromycin (C) 500 mg twice daily for 14 days (LAC) or L 30 mg four times daily, bismuth subsalicylate (B) 2 tablets four times daily, metronidazole (M) 250 mg four times daily and tetracycline (T) 250 ..
  88. ncbi In situ observation of oscillatory growth of bismuth nanoparticles
    Huolin L Xin
    Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Nano Lett 12:1470-4. 2012
    ..This study shed light on a new route for system engineering to reverse particle coursing by Ostwald ripening...
  89. pmc Zerovalent bismuth nanoparticles inhibit Streptococcus mutans growth and formation of biofilm
    Rene Hernandez-Delgadillo
    Instituto de Biotecnologia, Centro de Investigacion y Desarrollo en Ciencias de la Salud, CIDICS, Facultad de Odontologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Nuevo Leon, Mexico
    Int J Nanomedicine 7:2109-13. 2012
    ..Nanostructured materials are used in many fields, including biological sciences and medicine. While some bismuth derivatives has been used in medicine to treat vomiting, nausea, diarrhea, and stomach pain, the biocidal ..
  90. ncbi Interactions of bismuth with human lactoferrin and recognition of the Bi(III)-lactoferrin complex by intestinal cells
    L Zhang
    Department of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong, PRC
    Biochemistry 40:13281-7. 2001
    Several bismuth compounds are currently used as antiulcer drugs, but the mechanism of action still remains unclear...
  91. ncbi Determination of trace bismuth in human serum by cloud point extraction coupled flow injection inductively coupled plasma optical emission spectrometry
    Mei Sun
    Hefei National Laboratory for Physical Sciences on Microscale, University of Science and Technology of China, Hefei 230026, China
    J Hazard Mater 192:935-9. 2011
    A cloud point extraction method for the preconcentration of ultra-trace bismuth in human serum prior to its determination by inductively coupled plasma optical emission spectrometry had been developed in this paper...
  92. ncbi Radiopacity and histological assessment of Portland cement plus bismuth oxide
    Tauby Coutinho-Filho
    Department of Endodontics, Rio de Janeiro State University, Rio de Janeiro, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:e69-77. 2008
    The present study evaluated the subcutaneous connective tissue reactions and the radiopacity of MTA, Portland cement (PC), and Portland cement plus bismuth oxide (BO).
  93. ncbi A novel therapeutic approach for Helicobacter pylori infection: the bismuth-based triple therapy monocapsule
    W A de Boer
    Department of Internal Medicine, Ziekenhuis Bernhoven, Postbus 10, 5340 BE Oss, The Netherlands
    Expert Opin Investig Drugs 10:1559-66. 2001
    ..b>Bismuth-based triple therapy with bismuth, tetracycline and metronidazole is a well investigated, cheap and FDA approved ..
  94. ncbi Antimony(V) and bismuth(V) complexes of lapachol: synthesis, crystal structure and cytotoxic activity
    Ludmila G de Oliveira
    Departamento de Quimica, Instituto de Ciencias Exatas, Universidade Federal de Minas Gerais UFMG, Av Antonio Carlos 6627, 31270 901 Belo Horizonte, MG, Brazil
    Molecules 16:10314-23. 2011
    Antimony(V) and bismuth(V) complexes of lapachol have been synthesized by the reaction of Ph₃SbCl₂ or Ph₃BiCl₂ with lapachol (Lp) and characterized by several physicochemical techniques such as IR, and NMR spectroscopy and X-ray ..
  95. ncbi Bismuth-213 and actinium-225 -- generator performance and evolving therapeutic applications of two generator-derived alpha-emitting radioisotopes
    Alfred Morgenstern
    European Commission, Joint Research Centre, Institute for Transuranium Elements, 76125 Karlsruhe, Germany
    Curr Radiopharm 5:221-7. 2012
    ..Selected preclinical studies are highlighted and the current clinical experience with (225)Ac and (213)Bi is summarized...
  96. ncbi One-week regimens containing ranitidine bismuth citrate, furazolidone and either amoxicillin or tetracycline effectively eradicate Helicobacter pylori: a multicentre, randomized, double-blind study
    H Lu
    Shanghai Institute of Digestive Disease, Shanghai Second Medical University, Shanghai, China
    Aliment Pharmacol Ther 15:1975-9. 2001
    ..AIM: To evaluate the efficacy and safety of new 1-week regimens containing ranitidine bismuth citrate, furazolidone and either amoxicillin or tetracycline. METHODS: One hundred and twenty patients with H...
  97. pmc Conventional and pretargeted radioimmunotherapy using bismuth-213 to target and treat non-Hodgkin lymphomas expressing CD20: a preclinical model toward optimal consolidation therapy to eradicate minimal residual disease
    Steven I Park
    Department of Medicine, University of North Carolina, Chapel Hill, NC, USA
    Blood 116:4231-9. 2010
    ..of radioactivity at tumor sites, making it an optimal method to target α-emitters with short half-lives, such as bismuth-213 (²¹³Bi)...
  98. ncbi Synthesis and characterization of a stable bismuth(III) A3-corrole
    Lorenz Michael Reith
    Institute of Inorganic Chemistry, Johannes Kepler University Linz JKU, Altenberger Strasse 69, A 4040 Linz, Austria
    Inorg Chem 50:6788-97. 2011
    An efficient metalation procedure for bismuth complexes with meso-substituted corrole ligands is presented...
  99. ncbi Analysis of the healing response to gutta-percha and Diaket when used as root-end filling materials in periradicular surgery
    D E Witherspoon
    Department of Restorative Sciences, Graduate Endodontics, Baylor College of Dentistry, Texas A and M University System, Dallas, Texas, USA
    Int Endod J 33:37-45. 2000
    ..To analyse the healing response to gutta-percha and Diaket when used as root-end filling materials in periradicular surgery...
  100. ncbi Strategies to treat patients with antibiotic resistant Helicobacter pylori
    F Megraud
    Laboratoire de Bacteriologie, Hopital Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux Cedex, France
    Int J Antimicrob Agents 16:507-9. 2000
    ..The main rescuse therapy is a bismuth-based quadruple therapy...
  101. ncbi Gastrointestinal and systemic uptake of bismuth in mice after oral exposure
    Agnete Larsen
    Department of Neurobiology, Institute of Anatomy, University of Aarhus, Denmark
    Pharmacol Toxicol 93:82-90. 2003
    b>Bismuth compounds have been used in medicine for more than 200 years. In recent years, bismuth has gained renewed interest as a remedy for eradication of gastrointestinal pathogens, especially Helicobacter pylori...

Research Grants51

  1. Targeted therapy of pancreatic cancer with in vivo radionuclide generator
    Ekaterina Dadachova; Fiscal Year: 2012
    ..histones in PCa with specific mAb radiolabeled with powerful in vivo generator of alpha-particles 212-Lead/212-Bismuth (212Pb/212Bi) - we will be able to deliver high tumoricidal doses to the tumors without toxicity to normal ..
  2. Clinical Development of SQ109 for H. pylori Infection
    LISA BETH FERSTENBERG; Fiscal Year: 2013
    ..currently a regimen of 2 to 4 antibiotics administered for up to 14 days with a proton pump inhibitor or an oral bismuth preparation...
  3. Interaction of AIDS-associated microbes with radiation
    Ekaterina Dadachova; Fiscal Year: 2010
    ..We propose to utilize Lead-212/Bismuth-212 parent- daughter pair as an -emitter and radiolanthanides - as -emitters...
  4. Peptide-targeted alpha-particle emitting phage for ovarian cancer therapy.
    Thomas P Quinn; Fiscal Year: 2013
    ..or capsids filled with nanoparticles of lead-212 (212Pb), the parent of the alpha-particle emitting radionuclide bismuth-212 (212Bi), for directed intraperitoneal ovarian cancer treatment...
  5. Novel tungsten and bismuth nanoparticle contrast agents for MicroCT.
    Vishwas N Joshi; Fiscal Year: 2012
    ..We now propose to develop heavy metal nanoparticle contrast agents based on tungsten and bismuth that are lot cheaper than our gold-based contrast agents and more absorptive than iodine...
  6. Levodopa Pharmacokinetic Optimization by Metal Coordination
    Thomas Piccariello; Fiscal Year: 2013
    ..Some speculate that avoiding pulsatile delivery may slow the progression of PD. Synthonics found that bismuth forms a stable coordination complex with levodopa to form bismuth subdopate, the active ingredient in MCP-311...
  7. INORGANIC ION EXCHANGERS FOR 213BI GENERATORS
    Paul Sylvester; Fiscal Year: 1999
    ..Two classes of zirconium phosphonates have already achieved good bismuth separations from americium (a surrogate for actinium) and these results will be improved upon during Phase I...
  8. Targeted Nanoparticles of Bismuth Organo Complexes for Spectral CT Imaging of Cor
    Y Andrew Wang; Fiscal Year: 2013
    ..This NanoK platform technology offers unique benefits for diagnosis and treatment of acute coronary disease that could improve healthcare outcomes and reduce costs. ..
  9. DOUBLE-BLIND STUDY FOR LONG-TERM OF ULCER HEMORRHAGE
    Dennis Jensen; Fiscal Year: 1992
    ..to receive either a one time course of antimicrobial therapy (Metronidazole 250 TID, tetracycline 500mg TID, and bismuth subcitrate 240mg BID for two weeks) and an histamine 2 receptor antagonist (H2RA) placebo maintenance for the ..
  10. RADIOPAQUE ADHESIVES AND DENTAL RESTORATIVE RESINS
    ISRAEL CABASSO; Fiscal Year: 2000
    ..To obtain reactive, radiopaque, adhesive resin components we wiU: optimize the yield of the bismuth-styrene derivatives, synthesize Sb-styrene monomers, synthesize the Bi, Ti, Zr, and Hf derivatives of vinylbenzyl ..
  11. NATURAL HISTORY OF CAMPYLOBACTER ASSOCIATED GASTRITIS
    Pelayo Correa; Fiscal Year: 1990
    ..p. in chronic gastritis. In 1988 we will have completed in New Orleans a randomized trial of bismuth subsalicylate vs placebo in chronic active gastritis...
  12. LOW COST, HIGH PERFORMANCE HTS MAGNETS FOR NMR
    Michael Strauss; Fiscal Year: 2000
    ..However, high temperature superconductors are brittle ceramic materials (BSCCO is bismuth, strontium, calcium, copper oxide and YBCO is yttrium, barium, copper oxide)...
  13. ROLE OF CAMPYLOBACTER PYLORIDIS IN NON-ULCER DYSPEPSIA
    Robert Gilman; Fiscal Year: 1990
    ..However, a number of key questions remain open: 1. Are there safe, inexpensive antibiotics and/or colloidal bismuth preparations capable of being used for long periods of time which will erradicate CP from the gastric mucosa? 2...
  14. Bi(III)-Initiated Chemistry: Mechanistic Investigations of Catalytic Activity
    Robert Hinkle; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Bismuth compounds have recently blossomed as very useful reagents for organic synthesis and catalytic quantities initiate a wide-range of reactions...
  15. ANTIBODY THERAPY OF MICROMETASTASES
    George Sgouros; Fiscal Year: 1999
    ..gamma, breast), CC49 (anti-tag-72, Colorectal), and the single- chain fragment (sFv) of CC49 will be labeled with bismuth-213 (alpha- emitter, 46 min half-life), bismuth-205 (15.3 d) and indium-111 (2...
  16. Antimicrobial & Immunization for Bacterial Gastritis
    JOSEPH CUMMINS; Fiscal Year: 2005
    ..Combination antimicrobial therapy (triple therapy with a bismuth salt, metranidazole and a broad spectrum antibiotic) is successful in 80% of Hp-infected symptomatic patients; ..
  17. METALLOTHIONEIN AND ADRIAMYCIN CARDIOTOXICITY
    Y Kang; Fiscal Year: 2006
    ..and late-onset cardiotoxicity, we will develop an experimental strategy for a long-term cardiac MT induction by bismuth or hinokitiol in BALB/c mice...
  18. Pb-212 generator for cancer therapy
    Herbert Moore; Fiscal Year: 2004
    The long-term objective of this proposal is to develop a lead-212/bismuth-212 (Pb-212/bi-212) generator and sufficient amounts of source material that will support clinical trials and approved drug products...
  19. GENES OF H PYLORI ESSENTIAL FOR GASTRIC COLONIZATION
    Andrew Plaut; Fiscal Year: 1999
    ..protein, and experiments are proposed to correlate Hpn expression and protection from the toxic effects of bismuth in vivo...
  20. NEW, HIGH Z SEMICONDUCTOR SENSOR FOR POSITRON TOMOGRAPHY
    MICHAEL SQUILLANTE; Fiscal Year: 1991
    ..T1Br has the same effective Z as bismuth germinate (BGO), the leading scintillator material used for PET, and higher density...
  21. NOVEL APD/BGO DETECTOR ARRAY FOR HIGHER RESOLUTION PET
    Michael Paulus; Fiscal Year: 1993
    A new detector consisting of a monolithic array of silicon avalanche photodiodes (APDs) coupled to a bismuth germanate (BGO) scintillator array will be fabricated and tested...
  22. TWO MILLIMETER PET SCINTILLATION DETECTOR ARRAY
    WARD DIGBY; Fiscal Year: 1991
    ..The first will be an advance to the current "block" detector concept based on an 8x8 array of Bismuth Germanate (BGO), or Lead Sulfate (PbSO4) scintillation crystals coupled through a light guide to four ..
  23. THE ROLE OF MYCOBACTERIA IN CROHN'S DISEASE
    David Graham; Fiscal Year: 2005
    ..The results of this study should either confirm or refute the proposed etiologic association of M. paratuberculosis and Crohn's disease as well as the identification of patients with Crohn's disease and M. paratuberculosis. ..
  24. Interaction of AIDS-associated microbes with radiation
    Ekaterina Dadachova; Fiscal Year: 2009
    ..Such knowledge will contribute to development of a novel therapeutic modality based on radioimmunotherapy for treatment of currently incurable or multidrug-resistant AIDS-associated opportunistic infections. ..
  25. Radioimmunotherapy of opportunistic infections
    Ekaterina Dadachova; Fiscal Year: 2003
    ..We have radiolabeled mAb 18B7 with therapeutic radioisotopes 188-Rhenium (1 88-Re) and 21 3-Bismuth (21 3-Bi) and have shown that these radiolabeled antibodies can efficiently eradicate C...
  26. Rhenium-188 therapy of NIS-expressing breast tumors
    Ekaterina Dadachova; Fiscal Year: 2003
    ..The long-term goal of this research is to contribute to the development of a novel cost-effective radionuclide therapy for treatment of breast cancer and, possibly, for other NIS-expressing cancers such as thyroid cancer. ..
  27. ASTATINE AND IODINE RADIOLABELED MONOCLONAL ANTIBODIES
    Michael Zalutsky; Fiscal Year: 2008
    ..abstract_text> ..
  28. Targeted Alpha-Particle Emitter Therapy of Metastases
    George Sgouros; Fiscal Year: 2009
    ..The work described in this application is intended to develop and evaluate such an approach. ..
  29. MODELING AND DOSIMETRY FOR RADIOLABELED ANTIBODY THERAPY
    George Sgouros; Fiscal Year: 2002
    ....
  30. New Ligands for Radioimmunotherapy and MRI of Cancer
    Hyun Soon Chong; Fiscal Year: 2006
    ..The results of the proposed research will contribute to the development of better drugs for both MRI and RIT, which will greatly enhance clinical exploration of both modalities, and directly benefit cancer patients. ..
  31. Astatine 211 & Radioiodine Labeled Octreotide Conjugates
    Michael Zalutsky; Fiscal Year: 2004
    ..The proposed in vitro studies include characterization of binding, internalization and catabolism; the proposed in vivo studies include evaluation of tissue distribution, dosimetry, catabolism as well as therapeutic efficacy. ..
  32. MOLECULAR REGULATION OF SIGNALING BY IONIZING RADIATION
    Donald Kufe; Fiscal Year: 2002
    ....
  33. 4th Western Pacific Helicobacter Congress
    Barry Marshall; Fiscal Year: 2002
    ..Concurrent sessions will allow delegates to prioritise their sessions. ..
  34. MOLECULAR MECHANISMS OF ARA-C THERAPY IN MAN
    Donald Kufe; Fiscal Year: 2005
    ..abstract_text> ..
  35. Astatine-211 Conditioning for Nonmyeloablative Hematopoietic Stem Cell Allografts
    BRENDA MARIE SANDMAIER; Fiscal Year: 2010
    ..The final, and most important, studies will involve determining the quantity of 211At-labeled MAb required to obtain stable engraftment in HCT involvingDLA- haploidentical littermates. ..
  36. The biology of gastrin-ferric ion complexes
    GRAHAM BALDWIN; Fiscal Year: 2009
    ..Recognition that metal ions are essential for the biological activity of NAGs may permit the development of novel therapies for colon cancer. ..
  37. MACROPHAGE DERIVED FACTOR AND LEYDIG CELL FUNCTION
    JAMES HUTSON; Fiscal Year: 2001
    ..abstract_text> ..
  38. Early Detection of Lung Cancer via Bi Plane Correlation
    Ehsan Samei; Fiscal Year: 2002
    ..The findings will be used to demonstrate the capability of the approach for improving the detection of lung nodules, and thus the prognosis of lung cancer. ..
  39. IMPROVING THE DETECTION LIMIT OF POTENTIOMETRIC SENSORS
    Joseph Wang; Fiscal Year: 2008
    ..The perturbance of such fluxes by surface binding events will be used to explore novel approaches to biosensing at liquid-polymer interfaces. ..
  40. Resolution requirements for mammographic displays
    Ehsan Samei; Fiscal Year: 2004
    ..The results will be used to formulate recommendations to the breast imaging community concerning display resolution criteria for safe and optimized soft-copy display of digital mammograms. ..
  41. STEREOSELECTIVE SYNTHESIS OF CYCLIC ETHERS
    P Evans; Fiscal Year: 2006
    The aim of this proposal is the development of new tandem bismuth-catalyzed inter- and intramolecular etherification reactions for the construction of non-adjacent and fused polycyclic ethers...
  42. Ultraviolet-C Therapy for Onychomycosis
    MICHAEL HAMBLIN; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  43. NEW RHODIUM-CATALYZED ALLYLIC ALKYLATION REACTIONS
    P Evans; Fiscal Year: 2006
    ..The development of a temporary silicon-tethered (TST) rhodium-catalyzed [4+2+2] carbocyclization approach to the diterpene, epoxydictymene. ..
  44. Regulation of Oxidative Stress Response by c-Abl and Arg
    Donald Kufe; Fiscal Year: 2007
    ..abstract_text> ..
  45. H.pylori arginase modulation of ulcers and cancer
    David McGee; Fiscal Year: 2007
    ..pylori arginase in protection from innate defenses as well as roles in ulcer and cancer development and optimization of nitrogen levels in vivo. ..
  46. Macrophage Targeted Photodynamic Therapy
    MICHAEL HAMBLIN; Fiscal Year: 2004
    ....
  47. MECHANISMS OF CADMIUM TOXICITY IN EPITHELIAL CELLS
    WALTER PROZIALECK; Fiscal Year: 2007
    ..Furthermore, the results of these studies could have more general implications regarding the mechanisms by which toxic substances affect living organisms. ..
  48. Bi-Plane Correlation Imaging: Detection of Lung Cancer
    Ehsan Samei; Fiscal Year: 2007
    ..The findings will be used to substantiate the capability of BCI for improving the early detection of lung nodules and to optimize its performance on actual clinical cases. ..
  49. Enteric flora modulates the development of colitis
    Albert Jergens; Fiscal Year: 2008
    ..g., graduate students and postdoctoral fellow). There are ample opportunities to attend seminars, journal clubs and work-in-progress research meetings during which the applicant can become engaged in scientific discussions. ..
  50. Radioimmunotherapy of CD20+ Lymphomas & CD45+Leukemias
    JOHN PAGEL; Fiscal Year: 2008
    ..abstract_text> ..