dietary calcium

Summary

Summary: Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.

Top Publications

  1. ncbi Dietary calcium and magnesium intake and mortality: a prospective study of men
    Joanna Kaluza
    Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 171:801-7. 2010
  2. pmc Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1059-67. 2009
  3. ncbi Dietary influences of 1,25(OH)2 vitamin D in relation to prostate cancer: a hypothesis
    E Giovannucci
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Causes Control 9:567-82. 1998
  4. ncbi Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I
    Mitsumasa Umesawa
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Stroke 39:2449-56. 2008
  5. ncbi Randomized, placebo-controlled, calcium supplementation study in pregnant Gambian women: effects on breast-milk calcium concentrations and infant birth weight, growth, and bone mineral accretion in the first year of life
    Landing M A Jarjou
    Medical Research Council Keneba, Keneba, The Gambia
    Am J Clin Nutr 83:657-66. 2006
  6. ncbi High prevalence of low dietary calcium, high phytate consumption, and vitamin D deficiency in healthy south Indians
    Chittari V Harinarayan
    Departments of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India
    Am J Clin Nutr 85:1062-7. 2007
  7. ncbi The effect of dietary calcium on 1,25(OH)2D3 synthesis and sparing of serum 25(OH)D3 levels
    Paul H Anderson
    Chemical Pathology, SA Pathology, Frome Rd, Adelaide, SA 5000, Australia
    J Steroid Biochem Mol Biol 121:288-92. 2010
  8. ncbi Vitamin D status in a rural postmenopausal female population
    Joan M Lappe
    Creighton University Medical Center, Osteoporosis Research Center, 601 North 30 Street Suite 4820, Omaha, NE 68131, USA
    J Am Coll Nutr 25:395-402. 2006
  9. ncbi Calcium and dairy intakes in relation to long-term weight gain in US men
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Clin Nutr 83:559-66. 2006
  10. ncbi Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis
    Xiang Gao
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Natl Cancer Inst 97:1768-77. 2005

Detail Information

Publications349 found, 100 shown here

  1. ncbi Dietary calcium and magnesium intake and mortality: a prospective study of men
    Joanna Kaluza
    Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 171:801-7. 2010
    The authors examined the association of dietary calcium and magnesium intake with all-cause, cardiovascular disease (CVD), and cancer mortality among 23,366 Swedish men, aged 45-79 years, who did not use dietary supplements...
  2. pmc Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1059-67. 2009
    ..Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations...
  3. ncbi Dietary influences of 1,25(OH)2 vitamin D in relation to prostate cancer: a hypothesis
    E Giovannucci
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Causes Control 9:567-82. 1998
    ..The studies examining these dietary factors in relation to prostate cancer risk will be reviewed...
  4. ncbi Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I
    Mitsumasa Umesawa
    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Stroke 39:2449-56. 2008
    Although it has been hypothesized that a high intake of dietary calcium may reduce the risk of cardiovascular disease (CVD), no prospective studies have been conducted to examine the specific association between calcium intake and ..
  5. ncbi Randomized, placebo-controlled, calcium supplementation study in pregnant Gambian women: effects on breast-milk calcium concentrations and infant birth weight, growth, and bone mineral accretion in the first year of life
    Landing M A Jarjou
    Medical Research Council Keneba, Keneba, The Gambia
    Am J Clin Nutr 83:657-66. 2006
    ..A low maternal calcium supply in pregnancy may limit fetal mineral accretion and breast-milk calcium concentrations and thereby affect infant growth and bone mineral accretion...
  6. ncbi High prevalence of low dietary calcium, high phytate consumption, and vitamin D deficiency in healthy south Indians
    Chittari V Harinarayan
    Departments of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India
    Am J Clin Nutr 85:1062-7. 2007
    ..Data on the vitamin D status of the population in a tropical country such as India have seldom been documented. Vitamin D deficiency is presumed to be rare...
  7. ncbi The effect of dietary calcium on 1,25(OH)2D3 synthesis and sparing of serum 25(OH)D3 levels
    Paul H Anderson
    Chemical Pathology, SA Pathology, Frome Rd, Adelaide, SA 5000, Australia
    J Steroid Biochem Mol Biol 121:288-92. 2010
    ..However it is unclear whether modulation of dietary calcium intake impacts on the relationship between the level of serum 25-hydroxyvitamin D (25D) and bone loss...
  8. ncbi Vitamin D status in a rural postmenopausal female population
    Joan M Lappe
    Creighton University Medical Center, Osteoporosis Research Center, 601 North 30 Street Suite 4820, Omaha, NE 68131, USA
    J Am Coll Nutr 25:395-402. 2006
    ..Inadequate vitamin D nutritional status is increasingly recognized as common in North American and European populations, but the extent of the shortfall and the parameters of the distribution for populations of interest remain uncertain...
  9. ncbi Calcium and dairy intakes in relation to long-term weight gain in US men
    Swapnil N Rajpathak
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Clin Nutr 83:559-66. 2006
    ..The role of calcium in the maintenance of body weight remains controversial...
  10. ncbi Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis
    Xiang Gao
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Natl Cancer Inst 97:1768-77. 2005
    ..We conducted a meta-analysis to examine associations between intakes of calcium and dairy products and the risk of prostate cancer...
  11. ncbi Dairy products, calcium and phosphorus intake, and the risk of prostate cancer: results of the French prospective SU.VI.MAX (Supplémentation en Vitamines et Minéraux Antioxydants) study
    E Kesse
    Inserm U557 UMR Inserm Inra Cnam, ISTNA CNAM, Paris, France
    Br J Nutr 95:539-45. 2006
    ..The higher risk of prostate cancer with linear increasing yoghurt consumption seems to be independent of Ca and may be related to some other component...
  12. ncbi Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials
    R Christensen
    The Parker Institute, Musculoskeletal Statistics Unit, Frederiksberg Hospital, Frederiksberg, Denmark
    Obes Rev 10:475-86. 2009
    Observational studies have found that dietary calcium intake is inversely related to body weight and body fat mass. One explanatory mechanism is that dietary calcium increases faecal fat excretion...
  13. ncbi Regulation of adiposity and obesity risk by dietary calcium: mechanisms and implications
    Michael B Zemel
    The University of Tennessee, Knoxville 37996, USA
    J Am Coll Nutr 21:146S-151S. 2002
    b>Dietary calcium plays a pivotal role in the regulation of energy metabolism; high calcium diets attenuate adipocyte lipid accretion and weight gain during periods of overconsumption of an energy-dense diet and increase lipolysis and ..
  14. ncbi Vitamin D, parathyroid hormone levels and bone mineral density in community-dwelling older women: the Rancho Bernardo Study
    Denise G Von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Osteoporos Int 16:1721-6. 2005
    ..20). However, after the threshold vitamin D level of 120 nmol/l, all PTH values were below 65 ng/l. Further studies are necessary to identify the optimal vitamin D levels necessary to prevent secondary hyperparathyroidism...
  15. pmc Dietary calcium and serum 25-hydroxyvitamin D status in relation to BMD among U.S. adults
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    J Bone Miner Res 24:935-42. 2009
    ..To study the relative importance of dietary calcium intake and serum 25-hydroxyvitamin D [25(OH)D] status in regard to hip BMD, 4958 community-dwelling women and ..
  16. ncbi Dietary calcium and magnesium, major food sources, and risk of type 2 diabetes in U.S. black women
    Rob M van Dam
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 29:2238-43. 2006
    ..We examined magnesium, calcium, and major food sources in relation to type 2 diabetes in African-American women...
  17. ncbi Dairy and weight loss hypothesis: an evaluation of the clinical trials
    Amy Joy Lanou
    University of North Carolina at Asheville, Department of Health and Wellness, Asheville, North Carolina 28804, USA
    Nutr Rev 66:272-9. 2008
    ..Four of 24 trials report differential fat loss. Consequently, the majority of the current evidence from clinical trials does not support the hypothesis that calcium or dairy consumption aids in weight or fat loss...
  18. ncbi Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids
    Helen M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, United Kingdom
    Am J Clin Nutr 79:155-65. 2004
    ..The menopausal transition is characterized by rapid bone loss. Few data exist on the role of nutrition...
  19. pmc Dairy products, calcium and prostate cancer risk
    K A Koh
    Harvard University, 8 Garden Street, Cambridge, MA 02138, USA
    Br J Cancer 95:1582-5. 2006
    ..23 and 0.64, respectively), or calcium supplements was associated with prostate cancer risk (relative risk, 1.05; 95% confidence interval, 0.84-1.31)...
  20. ncbi Vitamin D status and its relationship with bone mineral density in healthy Asian Indians
    Vivek Arya
    Department of Endocrinology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Rae Bareli Road, 226014, Lucknow, India
    Osteoporos Int 15:56-61. 2004
    ..The serum 1,25(OH)(2)D level is not a good indicator of vitamin D deficiency. A low serum 25(OH)D level is possibly one of the reasons for lower bone mineral density among Indians...
  21. ncbi Skeletal abnormalities in Pth-null mice are influenced by dietary calcium
    Dengshun Miao
    Calcium Research Laboratory, Department of Medicine, McGill University Health Centre and Royal Victoria Hospital, McGill University, Montreal, Canada
    Endocrinology 145:2046-53. 2004
    ..They also show that, although PTH action is the first defense against hypocalcemia, 1,25(OH)(2)D(3) can be mobilized, even in the absence of PTH, to guard against extreme calcium deficiency...
  22. ncbi Effect of dietary calcium and 1,25-(OH)2D3 on the expression of calcium transport genes in calbindin-D9k and -D28k double knockout mice
    Sang Hwan Ko
    Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    Biochem Biophys Res Commun 379:227-32. 2009
    ..homeostasis, but that deletion of CaBP-9k and CaBP-28k has a significant effect on calcium processing under calcium-deficient conditions, confirming the importance of dietary calcium and 1,25-(OH)(2)D(3) during growth and development.
  23. ncbi Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese
    Hui Lee Wong
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Carcinogenesis 24:1091-5. 2003
    ..01). The effect of the VDR genotype on risk appeared to be modified by both dietary calcium and fat...
  24. ncbi Inhibitory effects of dietary calcium on the initial uptake and subsequent retention of heme and nonheme iron in humans: comparisons using an intestinal lavage method
    Zamzam K Fariba Roughead
    US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58202 9034, USA
    Am J Clin Nutr 82:589-97. 2005
    ..Calcium is the only reported dietary inhibitor of both heme- and nonheme-iron absorption. It has been proposed that the 2 forms of iron enter a common pool in the enterocyte and that calcium inhibits the serosal transfer of iron into blood...
  25. ncbi Choices for achieving adequate dietary calcium with a vegetarian diet
    C M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
    Am J Clin Nutr 70:543S-548S. 1999
    To achieve adequate dietary calcium intake, several choices are available that accommodate a variety of lifestyles and tastes. Liberal consumption of dairy products in the diet is the approach of most Americans...
  26. ncbi Meeting adequate intake for dietary calcium without dairy foods in adolescents aged 9 to 18 years (National Health and Nutrition Examination Survey 2001-2002)
    Xiang Gao
    Department of Nutrition, Harvard University School of Public Health, Boston, MA 02111, USA
    J Am Diet Assoc 106:1759-65. 2006
    In the United States, >50% of dietary calcium is provided by milk and milk products. Calcium intakes in the United States are inadequate for many children, and a large proportion do not drink milk or consume dairy products...
  27. ncbi Children who avoid drinking cow milk have low dietary calcium intakes and poor bone health
    Ruth E Black
    Department of Human Nutrition, University of Otago Medical School, Dunedin, New Zealand
    Am J Clin Nutr 76:675-80. 2002
    ..Information concerning the adequacy of bone mineralization in children who customarily avoid drinking cow milk is sparse...
  28. ncbi The combined effect of lead exposure and high or low dietary calcium on health and immunocompetence in the zebra finch (Taeniopygia guttata)
    Tinne Snoeijs
    Behaviour and Ecology Research Group, Department of Biology, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    Environ Pollut 134:123-32. 2005
    ..Here, we investigated the effects of chronic exposure to sublethal levels of lead, combined with high or low dietary calcium, on health and several components of immunity in male and female zebra finches (Taeniopygia guttata)...
  29. ncbi Dietary calcium intake and overweight: an epidemiologic view
    Milena Baptista Bueno
    University of Sao Paulo, Sao Paulo, Brazil
    Nutrition 24:1110-5. 2008
    ..We evaluated the relation between overweight and calcium intake in adults living in the municipality of São Paulo, Brazil...
  30. ncbi Short-term high dietary calcium intake during bedrest has no effect on markers of bone turnover in healthy men
    Natalie Baecker
    Deutsches Zentrum fuer Luft und Raumfahrt, Institute of Aerospace Medicine, Linder Hoehe, Cologne, Germany
    Nutrition 26:522-7. 2010
    ..Immobilization and space flight are causes of disuse osteoporosis. Increasing calcium intake may counteract this disuse-induced bone loss...
  31. ncbi The role of dairy foods and dietary calcium in weight management
    Marta Van Loan
    University of California Davis, CA 95616, USA
    J Am Coll Nutr 28:120S-9S. 2009
    ..paper provides a review of some of the scientific evidence that has examined the effect of dairy foods and dietary calcium on weight management...
  32. ncbi Milk, dairy fat, dietary calcium, and weight gain: a longitudinal study of adolescents
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 159:543-50. 2005
    ..Milk is promoted as a healthy beverage for children, but some researchers believe that estrone and whey protein in dairy products may cause weight gain. Others claim that dairy calcium promotes weight loss...
  33. pmc Dietary calcium and vitamin D intakes in childhood and throughout adulthood and mammographic density in a British birth cohort
    G Mishra
    MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, University College London, London, UK
    Br J Cancer 99:1539-43. 2008
    We examined the role of dietary calcium and vitamin D intakes in childhood and throughout adulthood in relation to mammographic density using data from a nationally representative cohort of 1161 women followed up since their birth in ..
  34. ncbi Diet and prostate cancer risk with specific focus on dairy products and dietary calcium: a case-control study
    Sara Raimondi
    Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy
    Prostate 70:1054-65. 2010
    ..Despite the prevalence of prostate cancer worldwide, only a few risk factors have been well-established. The role of diet, especially of dairy products, in the etiology of prostate cancer is still controversial...
  35. ncbi Dietary calcium and dairy modulation of adiposity and obesity risk
    Michael B Zemel
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1920, USA
    Nutr Rev 62:125-31. 2004
    b>Dietary calcium plays a key role in the regulation of energy metabolism and obesity risk...
  36. ncbi Dietary calcium attenuation of body fat gain during high-fat feeding in mice
    Pilar Parra
    Department of Fundamental Biology and Health Sciences, University of the Balearic Islands, Palma de Mallorca E 07122, Spain
    J Nutr Biochem 19:109-17. 2008
    ..Results support the anti-obesity effect of dietary calcium in male mice and indicate that, at least at the time-point studied, activation of thermogenesis is not ..
  37. ncbi Dietary calcium and vitamin D intake in an adult Middle Eastern population: food sources and relation to lifestyle and PTH
    Marie Hélène Gannagé-Yared
    Department of Endocrinology, Saint Joseph University, Beirut, Lebanon
    Int J Vitam Nutr Res 75:281-9. 2005
    ..People at most risk for secondary hyperparathyroidism should be advised to increase their dietary calcium (mostly animal calcium) and vitamin D, to take supplements, or to increase their sun exposure.
  38. ncbi High prevalence of low dietary calcium and low vitamin D status in healthy south Indians
    C V Harinarayan
    Department of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati 517 507, AP, India
    Asia Pac J Clin Nutr 13:359-64. 2004
    ..Compared to urban subjects, rural subjects had a significantly lower intake of dietary calcium (P <0...
  39. ncbi Children who avoid drinking cow's milk are at increased risk for prepubertal bone fractures
    Ailsa Goulding
    Department of Medical and Surgical Sciences, University of Otago Medical School, Dunedin, New Zealand
    J Am Diet Assoc 104:250-3. 2004
    ..Children who avoided milk did not use calcium-rich food substitutes appropriately and had low dietary calcium intakes and low bone mineral density values. Many were overweight (22 of 50)...
  40. ncbi The role of dietary calcium and other nutrients in moderating body fat in preschool children
    B R Carruth
    Nutrition Department, The University of Tennessee, Knoxville 37996 1900, USA
    Int J Obes Relat Metab Disord 25:559-66. 2001
    ..To assess preschool children's food consumption (24-60 months) and relate these findings to body composition at 70+/-2 months...
  41. ncbi Regulation of adiposity by dietary calcium
    M B Zemel
    Department of Nutrition, The University of Tennessee, Knoxville, Tennessee 37996 1900, USA
    FASEB J 14:1132-8. 2000
    ..We have also noted that increasing dietary calcium of obese patients for 1 year resulted in a 4.9 kg loss of body fat (P<0.01)...
  42. ncbi Dairy products, dietary calcium and vitamin D intake as risk factors for prostate cancer: a meta-analysis of 26,769 cases from 45 observational studies
    Michael Huncharek
    Division of Preventive Medicine, University of South Carolina School of Medicine, Columbia, South Carolina 29209, USA
    Nutr Cancer 60:421-41. 2008
    ..16; 95% CI = 0.98-1.38). The data from observational studies do not support an association between dairy product use and an increased risk of prostate cancer...
  43. ncbi Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women
    Simin Liu
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Diabetes Care 28:2926-32. 2005
    ..To examine whether and to what extent intakes of calcium and vitamin D are related to the metabolic syndrome in middle-aged or older women...
  44. ncbi Calcium intake, calcium bioavailability and bone health
    K D Cashman
    Nutritional Sciences, Department of Food Science, Food Technology and Nutrition, University College, Cork, Ireland
    Br J Nutr 87:S169-77. 2002
    ..This approach may be of particular value in individuals who fail to achieve the dietary recommended level of Ca...
  45. ncbi Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 86:1780-90. 2007
    ..The role of total calcium intake in the prevention of hip fracture risk has not been well established...
  46. ncbi Meat and dairy consumption and subsequent risk of prostate cancer in a US cohort study
    Sabine Rohrmann
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Rm E 6138, Baltimore, MD 21205, USA
    Cancer Causes Control 18:41-50. 2007
    ..To evaluate the association of meat and dairy food consumption with subsequent risk of prostate cancer...
  47. ncbi Dairy products do not lead to alterations in body weight or fat mass in young women in a 1-y intervention
    Carolyn W Gunther
    Departments of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 81:751-6. 2005
    ..Previous results suggested that increased intake of dairy calcium is associated with reduced weight and fat mass...
  48. ncbi Dietary calcium and vitamin D intake and risk of colorectal cancer: a prospective cohort study in women
    Paul Terry
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Nutr Cancer 43:39-46. 2002
    ..hazards models to estimate rate ratios and 95% confidence intervals, we found an inverse association between dietary calcium intake and colorectal cancer risk...
  49. ncbi Dairy, calcium, and vitamin D intakes and prostate cancer risk in the National Health and Nutrition Examination Epidemiologic Follow-up Study cohort
    Marilyn Tseng
    Division of Population Science, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Am J Clin Nutr 81:1147-54. 2005
    ..Dairy intake may increase prostate cancer risk, but whether this is due to calcium's suppression of circulating vitamin D remains unclear. Findings on calcium and vitamin D intake and prostate cancer are inconsistent...
  50. pmc Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial
    Mark J Bolland
    Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    BMJ 336:262-6. 2008
    ..To determine the effect of calcium supplementation on myocardial infarction, stroke, and sudden death in healthy postmenopausal women...
  51. ncbi Effect of supplementation of calcium and vitamin D on bone mineral density and bone mineral content in peri- and post-menopause women; a double-blind, randomized, controlled trial
    Nicola Di Daniele
    Human Nutrition Unit, Via Montpellier 1, University of Rome, Tor Vergata, 00173 Rome, Italy
    Pharmacol Res 50:637-41. 2004
    ..Osteoporosis is a serious global health problem for the future, that is why improving diagnostic methods and prevention of this disease could be helpful...
  52. ncbi Dietary calcium and vitamin D intake in relation to osteoporotic fracture risk
    Karl Michaelsson
    Department of Surgical Sciences, Orthopaedics, University Hospital, SE 751 85 Uppsala, Sweden
    Bone 32:694-703. 2003
    The etiologic role of dietary calcium and vitamin D intake in primary prevention of osteoporotic fractures is uncertain, despite considerable research efforts...
  53. ncbi Serum 25-hydroxyvitamin D, dietary calcium intake, and distal colorectal adenoma risk
    A J Levine
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089-9181, USA
    Nutr Cancer 39:35-41. 2001
    ..We assessed the associations between dietary vitamin D, plasma 25-hydroxyvitamin D [25(OH)D], dietary calcium, and colorectal adenomas in a large screening sigmoidoscopy-based case-control study in Southern California...
  54. ncbi Interactions of waterborne and dietary cadmium on the expression of calcium transporters in the gills of rainbow trout: influence of dietary calcium supplementation
    Fernando Galvez
    Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA
    Aquat Toxicol 84:208-14. 2007
    ..3 microg/L waterborne plus 500 mg/kg dietary Cd exposure, supplemented with either 20 mg/g or 60 mg/g dietary calcium (Ca(2+))...
  55. ncbi Bone CYP27B1 gene expression is increased with high dietary calcium and in mineralising osteoblasts
    Paul H Anderson
    Chemical Pathology, SA Pathology, Frome Rd, Adelaide, SA 5000, Australia
    J Steroid Biochem Mol Biol 121:71-5. 2010
    ..These findings confirm that the regulation of bone CYP27B1 is unique from that in the kidney, and may play an important role in bone formation...
  56. ncbi Calcium and weight: clinical studies
    Robert P Heaney
    Creighton University, Omaha, Nebraska 68131, USA
    J Am Coll Nutr 21:152S-155S. 2002
    ..5-3.0 kg lower body weight in adults. Taken together these data suggest that increasing calcium intake by the equivalent of two dairy servings per day could reduce the risk of overweight substantially, perhaps by as much as 70 percent...
  57. ncbi A prospective study of the effects of 1-year calcium-fortified soy milk supplementation on dietary calcium intake and bone health in Chinese adolescent girls aged 14 to 16
    Suzanne C Ho
    Department of Community and Family Medicine, Centre of Research and Promotion of Women s Health, School of Public Health, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin NT, Hong Kong SAR
    Osteoporos Int 16:1907-16. 2005
    ..We conclude that 375 ml calcium-fortified soymilk supplementation, or an equivalent of about two glasses, is among the effective strategies for bone acquisition and the optimization of peak bone mass in adolescent girls...
  58. pmc Dietary calcium is associated with body mass index and body fat in American Indians
    Sigal Eilat-Adar
    MedStar Research Institute, Hyattsville, MD 20783, USA
    J Nutr 137:1955-60. 2007
    American Indians have a high prevalence of obesity. Evidence supports a relationship between increased dietary calcium intake and lower body weight...
  59. pmc Radiological and biochemical resolution of nutritional rickets with calcium
    L M Oginni
    Department of Orthopaedic Surgery, College of Health Sciences, Obafemi Awolowo University, Ile Ife, Nigeria
    Arch Dis Child 88:812-7; discussion 812-7. 2003
    ..To determine the response to oral calcium in Nigerian children with rickets...
  60. ncbi Long-term dietary calcium intake and breast cancer risk in a prospective cohort of women
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 89:277-82. 2009
    ..However, prospective studies of calcium intake in relation to breast cancer incidence are sparse...
  61. pmc Can the controversial relationship between dietary calcium and body weight be mechanistically explained by alterations in appetite and food intake?
    Dorothy Teegarden
    Department of Foods and Nutrition, Purdue University, 700 West State Street, West Lafayette, Indiana, USA
    Nutr Rev 66:601-5. 2008
    ..Thus, this new evidence does not support the hypothesis that high calcium or dairy intake reduces appetite or food intake...
  62. ncbi Calcium intake of Asian, Hispanic and white youth
    Rachel Novotny
    University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
    J Am Coll Nutr 22:64-70. 2003
    ..To examine calcium intake and food sources among Asian, white and Hispanic youth, in order to develop and target interventions to improve calcium intake...
  63. ncbi Effects of dietary calcium intake on body weight and prevalence of osteoporosis in early postmenopausal women
    Massimo Varenna
    Department of Rheumatology, Gaetano Pini Institute, University of Milan, Milan, Italy
    Am J Clin Nutr 86:639-44. 2007
    High calcium intakes seem to be ineffective at reducing bone loss in early postmenopausal women. However, the inverse relation between calcium intake and body weight can attenuate the negative effect of a low dietary calcium intake.
  64. ncbi Dietary calcium and vitamin D2 supplementation with enhanced Lentinula edodes improves osteoporosis-like symptoms and induces duodenal and renal active calcium transport gene expression in mice
    Geun Shik Lee
    Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361 763, Republic of Korea
    Eur J Nutr 48:75-83. 2009
    ....
  65. ncbi Post-natal ontogeny of stanniocalcin gene expression in rodent kidney and regulation by dietary calcium and phosphate
    H Deol
    Department of Physiology, Faculty of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada
    Kidney Int 60:2142-52. 2001
    ..because STC is a regulator of renal phosphate transport, we also examined the effects of changing levels of dietary calcium and phosphate on renal levels of STC gene expression in adult rats...
  66. ncbi High dietary calcium intakes reduce zinc absorption and balance in humans
    R J Wood
    Mineral Bioavailability Laboratory, Jean Mayer US Department of Agriculture, HNRCA, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 65:1803-9. 1997
    ..Our findings suggest that high-calcium diets can reduce net zinc absorption and balance and may increase the zinc requirement in adult humans...
  67. ncbi Dietary calcium and body mass index in Portuguese children
    P Moreira
    Faculty of Nutrition, University of Porto, Porto, Portugal
    Eur J Clin Nutr 59:861-7. 2005
    ..The objective of our study was to assess nutritional intake in school children (7-9-y-old) and relate calcium intake to body mass index (BMI)...
  68. ncbi Osteoporosis in India--the nutritional hypothesis
    A Gupta
    Department of Medicine, Henry Ford Hospital, Detroit, Michigan, USA
    Natl Med J India 9:268-74. 1996
    ..These measures, coupled with health education of the masses, should help promote bone health and control osteoporosis in India...
  69. ncbi Effects of dietary calcium restriction and acute exercise on the antioxidant enzyme system and oxidative stress in rat diaphragm
    Masayuki Itoh
    Fifth Dept of Internal Medicine, Tokyo Medical Univ, 3 20 1, Chuou, Ami, Inashiki, Ibaraki 300 0395, Japan
    Am J Physiol Regul Integr Comp Physiol 287:R33-8. 2004
    ..to increase intracellular calcium level; thus the aim of the current study was to elucidate whether dietary calcium restriction enhanced exercise-induced oxidative stress in rat diaphragm...
  70. ncbi Role of adequate dietary calcium intake in the prevention and management of salt-sensitive hypertension
    D A McCarron
    Division of Nephrology, Hypertension, and Clinical Pharmacology, Oregon Health Sciences University, Portland 97201, USA
    Am J Clin Nutr 65:712S-716S. 1997
    ....
  71. ncbi Calcium and dairy food intakes are inversely associated with colorectal cancer risk in the Cohort of Swedish Men
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 83:667-73; quiz 728-9. 2006
    ..Recent epidemiologic studies have generally reported a modest inverse association between calcium intake and the risk of colorectal cancer. However, findings pertaining to specific subsites in the colorectum have been conflicting...
  72. ncbi Prevalence and predictors of deficient dietary calcium intake during the third trimester of pregnancy: the experience of a developing country
    Atef M Darwish
    Department of Obstetrics and Gynecology, Assiut University, Assiut, Egypt
    J Obstet Gynaecol Res 35:106-12. 2009
    To assess the prevalence and predictors of dietary calcium deficiency in the third trimester of pregnancy.
  73. ncbi Ileal microbiota of growing pigs fed different dietary calcium phosphate levels and phytase content and subjected to ileal pectin infusion
    B U Metzler-Zebeli
    Institute of Animal Nutrition, University of Hohenheim, 70599 Stuttgart, Germany
    J Anim Sci 88:147-58. 2010
    ..Greater intestinal Ca availability decreased the numbers of some gram-positive bacteria, whereas greater P availability in the small intestine caused by phytase activity enhanced the growth of strictly anaerobic bacteria...
  74. ncbi Osteoporosis prevention project: a model multidisciplinary educational intervention
    Linda S Brecher
    Department of Medicine, University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford 08084, USA
    J Am Osteopath Assoc 102:327-35. 2002
    ..No other group differences were found between the two groups. These findings suggest that a multidisciplinary education program may have an impact on knowledge and behaviors that may help to delay the development of osteoporosis...
  75. ncbi Calcium metabolism and dietary calcium in salt sensitive hypertension
    J R Sowers
    Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201
    Am J Hypertens 4:557-63. 1991
    ..especially likely to be characterized by abnormalities of calcium metabolism and blood pressure responses to dietary calcium. In this review the role of calcium in the regulation of blood pressure is examined with an emphasis on ..
  76. ncbi Lead content of dietary calcium supplements available in Brazil
    J C P Mattos
    Departamento de Quimica, Centro Naturais e Exatas, Universidade Federal de Santa Maria, Brazil
    Food Addit Contam 23:133-9. 2006
    ..5 microg g(-1) calcium), but none exceeded the federal limit of USA (7.5 microg g(-1) calcium) or the provisional tolerable lead intake by FAO/WHO (25 microg kg(-1) per week)...
  77. ncbi Dietary calcium, protein, and phosphorus are related to bone mineral density and content in young women
    D Teegarden
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
    Am J Clin Nutr 68:749-54. 1998
    ..Dietary factors have been implicated in modifying bone health, although the results remain controversial, particularly in young women...
  78. ncbi Effects of physical activity and dietary calcium intake on bone mineral density and osteoporosis risk in a rural Thai population
    C Pongchaiyakul
    Division of Endocrinology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Osteoporos Int 15:807-13. 2004
    ..b>Dietary calcium intake (g/day), energy expenditure (kcal/day), and sunlight exposure (h/day) were assessed in 129 rural Thai ..
  79. ncbi Calcium intake and adiposity
    Shamik J Parikh
    Unit on Growth and Obesity, Developmental Endocrinology Branch, National Institute of Child Health and Development, National Institutes of Health, Bethesda, MD 20892 1862, USA
    Am J Clin Nutr 77:281-7. 2003
    Limited epidemiologic and experimental data support the possibility that dietary calcium intake plays a role in human body weight regulation...
  80. ncbi Dietary calcium intake and serum vitamin D are major determinants of bone mass variations in women. A longitudinal study
    Antonio Del Puente
    Rheumatology Unit, University Federico II, Napoli, Italy
    Aging Clin Exp Res 14:382-8. 2002
    ..The aim of the study was to investigate the predictive value of both serological and questionnaire variables for bone mass variations in healthy women participating in a population-based longitudinal study carried out in Napoli, Italy...
  81. ncbi Dietary calcium, vitamin D, VDR genotypes and colorectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84108, USA
    Int J Cancer 111:750-6. 2004
    ..The risk associated with VDR genotype seems to depend upon the level of dietary calcium and vitamin D and tumor site.
  82. ncbi Bone and gastric bypass surgery: effects of dietary calcium and vitamin D
    Lisa R Goode
    Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey 08901, USA
    Obes Res 12:40-7. 2004
    ..To examine bone mass and metabolism in women who had previously undergone Roux-en-Y gastric bypass (RYGB) and determine the effect of supplementation with calcium (Ca) and vitamin D...
  83. ncbi Bone mass changes in vivo during the entire reproductive cycle in rats feeding different dietary calcium and calcium/phosphorus ratio content
    S Zeni
    Sección Osteopatías Médicas del Hospital de Clínicas J de San Martín, Facultad de Medicina, Universidad de Buenos Aires, Argentina
    Calcif Tissue Int 73:594-600. 2003
    ..05) and there were no differences between LCD and HCD. This in vivo study showed that regardless of the dietary calcium content, the maternal skeleton is slightly affected by pregnancy but severely affected by lactation...
  84. ncbi Impact of dairy products and dietary calcium on bone-mineral content in children: results of a meta-analysis
    Michael Huncharek
    Division of Preventive Medicine, University of South Carolina School of Medicine, Columbia, SC, 29209, USA
    Bone 43:312-21. 2008
    ..A meta-analysis was conducted to examine the impact of dietary calcium/dairy supplementation on bone mineral content in this age group.
  85. ncbi Physical activity and dietary calcium interactions in bone mass in Scottish postmenopausal women
    A Mavroeidi
    School of Medical Sciences, University of Aberdeen, Aberdeen, UK
    Osteoporos Int 20:409-16. 2009
    ..interactions between the mechanical component of self-reported habitual physical activity (PA) and dietary calcium (Ca) in BMD, independent of other risk factors...
  86. pmc Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium
    Fabrice Pierre
    UMR1089 Xenobiotiques, INRA ENVT, 23 ch Capelles, Toulouse, France
    Br J Nutr 99:1000-6. 2008
    ..They suggest that Ca can reduce colorectal cancer risk in meat-eaters. The results support the concept that toxicity associated with the excess of a useful nutrient may be prevented by another nutrient...
  87. ncbi Combined effect of dietary calcium and iron on colonic aberrant crypt foci, cell proliferation and apoptosis, and fecal bile acids in 1,2-dimethylhydrazine-treated rats
    Z Liu
    Department of Applied Biochemistry, Faculty of Biological Science, Hiroshima University, Higashi-Hiroshima 739-8528, Japan
    Oncol Rep 8:893-7. 2001
    ....
  88. ncbi Effect of low or high dietary calcium on the morphology of the rat femur
    H Chen
    Department of Anatomy, Gifu University School of Medicine, 40 Tsukasa Machi, Gifu 500 8705, Japan
    Histol Histopathol 17:1129-35. 2002
    ..Reversing the low income calcium intake by a higher calcium diet can partially improve the bone alternations induced by low calcium intake...
  89. ncbi Adiposity-related protection of intestinal tumorigenesis: interaction with dietary calcium
    S Ding
    Department of Nutrition, University of Tennessee, Knoxville, TN 37996 1920, USA
    Nutr Cancer 58:153-61. 2007
    ..Since we previously demonstrated that increasing dietary calcium reduces adiposity, and Apc(Min/+) mice on high calcium diets exhibited profound loss of adipose tissue, we ..
  90. ncbi Normalizing calcium intake: projected population effects for body weight
    Robert P Heaney
    Creighton University, Omaha, NE, USA
    J Nutr 133:268S-270S. 2003
    ....
  91. ncbi Geometric indices of bone strength are associated with physical activity and dietary calcium intake in healthy older women
    Michelle K Nurzenski
    School of Physiotherapy, Curtin University of Technology, and Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Western Australia, Australia
    J Bone Miner Res 22:416-24. 2007
    ..4-4.4% higher femoral bone strength in axial compression and 1.7-5.2% in bending than those achieving low levels, indicating that lifestyle factors influence bone strength in the proximal femur...
  92. pmc Effect of dietary calcium and dairy proteins on the adipose tissue gene expression profile in diet-induced obesity
    Taru K Pilvi
    Institute of Biomedicine, Pharmacology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Nutrigenet Nutrigenomics 1:240-51. 2008
    ..We have shown that a high-calcium diet with whey protein attenuates weight gain and now we describe the effects of this diet on adipose tissue gene expression...
  93. ncbi Influence of dietary calcium content on intestinal permeability in rat
    J Prakasa Rao
    Department of Pharmacology, Texas Tech Univeristy Health Sciences Center, Lubbock, TX, USA
    Indian J Med Res 129:681-4. 2009
    ..An increase in the permeability of the intestinal epithelium may account for this observation. The present study was aimed at monitoring the permeability of intestine of rats fed high or low calcium diets...
  94. ncbi Development of parathyroid gland hyperplasia without uremia: role of dietary calcium and phosphate
    Antonio Canalejo
    Department of Environmental Biology and Public Health, University of Huelva, Huelva, Spain
    Nephrol Dial Transplant 25:1087-97. 2010
    ..The recovery from the HPD or LCD to a control diet results in a more rapid reduction in PTH than in cell proliferation...
  95. ncbi High impact exercise is more beneficial than dietary calcium for building bone strength in the growing rat skeleton
    J M Welch
    Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    Bone 42:660-8. 2008
    The benefits of impact exercise and dietary calcium on bone development are controversial...
  96. ncbi Dietary calcium and 1,25-dihydroxyvitamin D3 regulate transcription of calcium transporter genes in calbindin-D9k knockout mice
    Sang Hwan Ko
    Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Chungbuk, Korea
    J Reprod Dev 55:137-42. 2009
    ..Taken together, these results suggest that the active calcium transporting genes in KO mice may have resistance to the deficiency diet of calcium and vitamin D(3)...
  97. ncbi The acute effects of different sources of dietary calcium on postprandial energy metabolism
    Nicola K Cummings
    Program of Nutrition, Dietetics and Food Science, School of Public Health, Curtin University of Technology, GPO Box U1987, Perth, WA 6845, Australia
    Br J Nutr 96:138-44. 2006
    ..No differences in diet-induced thermogenesis, insulin or glucose were observed. Regardless of source, Ca intake acutely stimulated postprandial fat oxidation; and there was a lesser suppression of NEFA following these meals...
  98. ncbi Are low intakes of calcium and potassium important causes of cardiovascular disease?
    D A McCarron
    Department of Medicine, Oregon Health Sciences University, Portland 97205 2110, USA
    Am J Hypertens 14:206S-212S. 2001
    ..Adequate intake of minerals such as calcium and potassium-specifically derived from foods, where they coexist with other essential nutrients-contributes to cardiovascular as well as overall health...
  99. ncbi Does dietary calcium have a protective effect on bone fractures in women? A meta-analysis of observational studies
    Liangzhi Xu
    Centre for Clinical Epidemiology and Biostatistics, School of Population Health Sciences, Faculty Health, The University of Newcastle, Australia
    Br J Nutr 91:625-34. 2004
    ..01, 95 % CI 0.96, 1.07 for each increment of 300 mg dietary Ca intake/d). There is a suggestion that either extremely low Ca intake may increase fracture risk, or that East Asian women may respond differently to increasing Ca intake...
  100. ncbi Intestinal polyp formation in the Apcmin mouse: effects of levels of dietary calcium and altered vitamin D homeostasis
    Sergio Huerta
    UCLA Center for Human Nutrition, Los Angeles, California 90095, USA
    Dig Dis Sci 48:870-6. 2003
    This study evaluated the effects of various levels of dietary calcium on polyp formation, vitamin D homeostasis, and fecal bile acids in the Apcmin mouse...
  101. ncbi Multiple sources of dietary calcium-some aspects of its essentiality
    Lawrence Fishbein
    4320 Ashford Lane, Fairfax, VA 22032, USA
    Regul Toxicol Pharmacol 39:67-80. 2004
    ....

Research Grants65

  1. The Effect of PTHrP During Lactation
    John J Wysolmerski; Fiscal Year: 2010
    ..This feedback loop may be particularly important to protect the mother from hypocalcemia when dietary calcium supplies are limiting...
  2. Diet by Gene Interactions Affecting Calcium and Bone Metabolism
    James C Fleet; Fiscal Year: 2010
    ..Our long-term goal is to identify the genetic variants that influence an individual's response to low dietary calcium intake and then use this information as a foundation for making personalized diet recommendations to optimize ..
  3. Control of Colonic Inflammation and Tumor Growth by TGFBeta and Dietary Vitamin D
    Lillian Maggio-Price; Fiscal Year: 2012
    ..Animal and epidemiological studies suggest that diet strongly influences cancer incidence, and inadequate dietary calcium and vitamin D are associated with increased risk of colorectal cancer...
  4. Claudin-2, Claudin-12 and Cadherin-17: Novel Targets of Vitamin D Action
    ANGELA R PORTA; Fiscal Year: 2011
    ..of vitamin D deficient mice and after 1,25(OH)2D3 administration, and (2) under conditions of high and low dietary calcium conditions...
  5. Ligand independent signaling by VDR in Keratinocytes
    Paul N MacDonald; Fiscal Year: 2010
    ..D3 (1,25(OH)2D3) is to maintain appropriate calcium homeostasis by ensuring adequate intestinal absorption of dietary calcium. However, 1,25(OH)2D3 and its cognate receptor, the vitamin D receptor (VDR), also have critical roles in the ..
  6. Vitamin D Hormone: Function and Mechanism of Action
    SYLVIA S CHRISTAKOS; Fiscal Year: 2010
    ..on 1,25(OH)2D3 regulated intestinal calcium absorption and on active calcium transport under low dietary calcium conditions...
  7. Synergistic effects of conjugated linoleic acid and calcium on bone mass
    Yeonhwa Park; Fiscal Year: 2009
    ..The main emphasis of prevention strategies has been on dietary calcium intake, however calcium by itself has limited efficacy...
  8. Identifying Risk Factors and Improving Risk Assessment for Nephrolithiasis
    Eric N Taylor; Fiscal Year: 2013
    ..However, KS formers have lower dietary calcium and higher urinary calcium than individuals without KS...
  9. Subclinical CVD in African American Type 2 Diabetics
    BARRY IRA FREEDMAN; Fiscal Year: 2013
    ..AAs also manifest lower rates of osteoporosis despite lower vitamin D levels and ingestion of less dietary calcium than EAs...
  10. Diet and the Calcium Channel TRPV6 in Colon Hyperplasia
    Sara Peleg; Fiscal Year: 2010
    ..TRPV6 in the infected colon and a significant repression of this gene in the colon of infected mice given 1% dietary calcium. Since elevated expression of TRPV6 was found in other malignancies, including colon cancer, we hypothesized ..
  11. X-LINKED HYPOPHOSPHATEMIA: IGF-1 INHIBITORS
    Ralph Meyer; Fiscal Year: 1990
    ..4) Hyp mice will be treated with 1.25-dihydroxyvitamin D or increased dietary calcium and phosphate to restore skeletal growth...
  12. OSTEOPOROSIS/DIHYDROXYVITAMIN REGULATED GENE EXPRESSION
    Sylvia Christakos; Fiscal Year: 1993
    ..and sex on intestinal and renal responsiveness to l,25(OH)2D3 or vitamin D3 and on adaptation to changes in dietary calcium. Three, 6, 12 and 24 month old male and female rats will be fed a strontium diet (0...
  13. REPRODUCTIVE DEVELOPMENT & BONE ACCRETION IN YOUNG WOMEN
    Thomas Lloyd; Fiscal Year: 1999
    ..from age 12 through age 15 and determined that among well-nourished girls cumulative estrogen exposure and dietary calcium intake are the most powerful determinants of bone gain during early and mid-adolescence...
  14. Psychophysics of Divalent Salts and Metallic Taste
    HARRY LAWLESS; Fiscal Year: 2006
    ..Given the aging of the US population and the prevalence of osteoporosis, dietary calcium insufficiency is a growing concern and is being addressed by an increasing number of calcium fortified food ..
  15. RECTAL MUCOSAL PROLIFERATION INDICES--EFFECTS OF CALCIUM
    John Baron; Fiscal Year: 1992
    ..In addition to changes in dietary fat and fiber, an increase in dietary calcium has been proposed to reduce the risk of large bowel cancer...
  16. CALCIUM AND COLORECTAL EPITHELIAL CELL PROLIFERATION
    John Potter; Fiscal Year: 1992
    Promising, but as yet inconclusive evidence has been accumulating to indicate that dietary calcium in sufficient quantity, may be a protective factor against colorectal cancer--particularly for those consuming typical high fat Western-..
  17. Calcium for Prevention of Postpartum Depression
    Daniel Hatton; Fiscal Year: 2004
    ..Preliminary studies indicate that dietary calcium supplementation during pregnancy may provide an inexpensive, safe, and effective protection against ..
  18. ROLE OF CALCIUM AND CAFFEINE IN GALLSTONE DISEASE
    Keith Lillemoe; Fiscal Year: 1993
    ..In this proposal, we will define the role of dietary calcium and caffeine, two important components of the American diet, in pathogenesis and prevention of gallstones...
  19. CALCIUM AND VITAMIN D MALNUTRITION IN ELDERLY WOMEN
    Joan Lappe; Fiscal Year: 2003
    ..Calcium nutritional deficiency may be due to low dietary calcium as well as low 25(OH)D which promotes calcium absorption...
  20. Regulation of minerals and fluids excretion in vitamin D
    Yan Chun Li; Fiscal Year: 2005
    ..The first aim is to study the effect of VDR inactivation, 1,25(OH)2-vitamin D deficiency, and dietary calcium on the expression of renal CaBP-D9k and its role in calcium reabsorption...
  21. BUILDING BETTER BONES IN CHILDREN
    Babette Zemel; Fiscal Year: 2003
    ..Increased dietary calcium from daily and other food sources may have an even greater impact on bone density than that achieved by ..
  22. AUTONOMIC NEURAL EFFECTS OF DIETARY CALCIUM
    JACOB PEULER; Fiscal Year: 1992
    ..In addition, I will test the hypothesis that high NaCl intake induces ionic and hormonal hypocalcemia in Dahl S but not R rats, a condition which may contribute to their neurogenic hypertension and may be normalized by high Ca ingestion...
  23. CALCIUM IN THE PREVENTION OF NEOPLASTIC POLYPS
    John Baron; Fiscal Year: 2003
    ..Further evidence that dietary calcium may preferentially affect the risk of adenomas harboring ras mutations needs confirmation...
  24. MENOPAUSE, AGING & OSTEOPOROSIS--CROSS-CULTURAL INQUIRY
    Yewoubdar Beyene; Fiscal Year: 1992
    ..bone density studies, and complete reproductive history of 100 rural and 100 urban Mayan women, as well as dietary calcium analysis in local foods...
  25. INDUCIBLE ALTERATION OF CGRP IN PRIMARY AFFERENT NEURONS
    KARIN WESTLUND HIGH; Fiscal Year: 1993
    ..In the dietary model, low dietary calcium induces a reduction of CGRP in laminae I and H in young rats while high calcium in the diet increases levels ..
  26. CALCIUM OXALATE IN BIOLOGICAL SYSTEMS
    ROSS HOLMES; Fiscal Year: 1999
    ..of microorganisms to metabolize oxalate, nutritionists who study the absorption and bioavailability of dietary calcium and oxalate, physiologists who examine the transport of calcium and oxalate and their interaction with organs,..
  27. KHCO3 PREVENTS NACL INDUCED BONE RESORPTION IN HUMANS?
    Anthony Sebastian; Fiscal Year: 1999
    ..leads to homeostatic adjustments of parathyroid and vitamin D activity that increase intestinal absorption of dietary calcium. This endocrinologic- gastrointestinal response appears to be impaired in older subjects...
  28. SODIUM AND CALCIUM METABOLISM IN PREHYPERTENSIVE STATE
    Vito Campese; Fiscal Year: 1990
    ..Moreover, the mechanisms of the hypotensive effect of increased dietary calcium intake in SHR are not elucidated...
  29. MATRIX GLA PROTEIN AND CARTILAGE CALCIFICATION
    Paul Price; Fiscal Year: 2001
    ..Finally, they will establish the role of MGP as a mediator of the action of 1,25(OH)2D3 on bone dietary calcium deficiency...
  30. CALCIUM INTAKE, METABOLISM & GESTATIONAL BLOOD PRESSURE
    Cynthia Morris; Fiscal Year: 1990
    The importance of maintaining dietary calcium intake and normal calcium metabolism for optimal regulation of arterial pressure in humans and experimental models has been demonstrated by us and other investigators...
  31. Effect of high dairy, high non-dairy and low calcium diet on weight and fat loss
    JANET WHATLEY BLUM; Fiscal Year: 2007
    ..Furthermore, dairy foods, which are rich in calcium (dietary calcium), may be more effective than non-food calcium supplements (calcium pills) in helping people lose weight and ..
  32. OVARIAN TOXICITY OF GALACTOSE
    Claude Hughes; Fiscal Year: 1999
    ..Decreased intake of lactose-rich foods (primarily dairy products) and increased alternative sources of dietary calcium may have to be advocated to maintain a normal reproductive life span and to prevent an increased risk of ..
  33. ADAPTIVE MECHANISM TO LOW CALCIUM INTAKE DURING PUBERTY
    Steven Abrams; Fiscal Year: 2000
    ..Girls in Group 1 then will have their dietary calcium intake decreased to 400 mg/day for 21 days, and calcium studies will be repeated...
  34. LONG TERM EFFECT OF CA++ ON BONE MASS IN YOUNG FEMALES
    Velimir Matkovic; Fiscal Year: 2000
    DESCRIPTION (Adapted from the Applicant's Abstract): It was originally suggested (by the applicants) that dietary calcium is an important determinant of bone mass in young adults...
  35. Calcium Channel CaT 1 in Prostate Cancer Prevention
    Stephen Hsu; Fiscal Year: 2007
    ..There is substantial epidemiologic evidence that an excess of dietary calcium, mainly from dietary sources, increases the risk of prostate cancer...
  36. RANDOMIZED CALCIUM TRIAL IN HIGH RISK PREGNANCIES
    JORGE PRADA; Fiscal Year: 1999
    ..Recent studies suggest that conventional dietary calcium intake during pregnancy may be inadequate to maintain a positive calcium balance and optimal bone metabolism, ..
  37. BONE LEAD STORES AND PREGNANCY INDUCED HYPERTENSION
    John Bogden; Fiscal Year: 1999
    ..relationships during pregnancy among five factors: blood pressure, temporal changes in blood lead, dietary calcium intake, current lead ingestion, and bone lead mobilization...
  38. BIOBEHAVIORAL RISK FACTORS FOR BONE LOSS IN ATHLETES
    Kenneth Ward; Fiscal Year: 2002
    ..2) to identify risk factors for bone mineral loss among adolescent athletes, including gender, race, body composition, dietary calcium intake, reproductive hormone status, and training intensity.
  39. Dairy Product Intake Regulation of Energy Metabolism
    Dorothy Teegarden; Fiscal Year: 2007
    ..b>Dietary calcium may reduce body weight and fat mass, however, recent studies demonstrate that this effect is enhanced by ..
  40. EFFECT CA++ FOODS ON BONE QUALITY IN PUBERTAL FEMALES
    Joan Lappe; Fiscal Year: 2001
    ..The aim of this experimental study is to test the effect of increasing dietary calcium intake to 1500 mg/day on increases in bone quality in pubertal females at age nine...
  41. PROSTATE CANCER, CALCIUM AND VITAMIN D
    JoEllen Welsh; Fiscal Year: 2007
    Despite epidemiological evidence linking dietary calcium and vitamin D to prostate cancer risk, the limited availability of basic and pre-clinical research precludes the development of specific recommendations regarding intake of these ..
  42. The role of the extracellular calcium-sensing receptor in dietary Ca2+ chemopreve
    Joel Mason; Fiscal Year: 2007
    ..b>Dietary calcium has been shown to have a chemopreventive effect on colon tumorigenesis in both humans and mice...
  43. BONE MASS & NUTRITIONAL STATUS OF CHILDREN WITH FRACTURE
    Velimir Matkovic; Fiscal Year: 2001
    ..and adolescents with distal forearm fracture as well as in normal controls; and 2) the determination of dietary calcium intakes in cases and control...
  44. VASCULAR ACTIONS OF PTH IN HEALTH AND DISEASE
    GEORGE NICKOLS; Fiscal Year: 1990
    ..Also, considering the recent interest in calcium metabolism and hypertension, studies of the effects of dietary calcium on the development of genetic hypertension and hyperparathyroidism will be performed...
  45. Kcitrate, Thiazides, or Combination to Prevent Bone Loss
    Deborah Sellmeyer; Fiscal Year: 2001
    ..Nutritional supplements to optimize dietary intake can improve bone health. For example, dietary calcium and vitamin D intake is often sub-optimal; supplements can reduce bone loss and fracture risk...
  46. ANTECEDENTS OF PEAK BONE MASS IN BLACK & WHITE WOMEN
    SUE KIMM; Fiscal Year: 2001
    ..The main hypotheses involve the effects of dietary calcium, vitamin D, physical activity, and pubertal maturation on BMD, and their interaction with each other as well ..
  47. BONY EFFECTS OF TRANSIENT NONSKELETAL ILLNESS
    Robert Heaney; Fiscal Year: 2001
    ....
  48. EFFECTS OF NUTRIENTS IN HYPERTENSION
    ROSE ROBERTSON; Fiscal Year: 1993
    ..application requests support for the completion of a nutritional study of the effects and interactions of dietary calcium and sodium in patients with essential hypertension...
  49. Bone-Sparing by Ca Salts With & Without Extra Phosphorus
    Robert Heaney; Fiscal Year: 2008
    ..1 Description, ..
  50. Role of TRPV6 in Gender and Age Dependent Alterations in Calcium Homeostasis
    Bryan Benn; Fiscal Year: 2009
    ..and gender on 1,25(OH)2D3 regulated intestinal calcium absorption and on active calcium transport under low dietary calcium conditions in the TRPV6 KO mouse. 3...
  51. TREATMENT OF CALCIUM DEFICIENCY IN YOUNG WOMEN
    Robert Heaney; Fiscal Year: 1999
    ..Whereas intakes at the 1989 RDAs would yield a dietary calcium-to-protein ratio of 26 mg/g, prevailing intakes among female subjects in their 20s average only about 12 mg/g...
  52. BEHAVIORAL STRATEGIES TO PREVENT OSTEOPOROSIS IN GIRLS
    Simone French; Fiscal Year: 2003
    ..Intervention components focus on behavioral skills development, goal setting, and self-monitoring for dietary calcium intake and physical activity, and increasing social support from peers and parents...
  53. RISK FACTORS FOR ADVANCED PROSTATE CANCER
    Sue Ingles; Fiscal Year: 2003
    ..Are polymorphisms in the vitamin D receptor gene associated with risk of advanced prostate cancer? 4. Does dietary calcium intake or vitamin D status (as measured by sunlight exposure and dietary intake) modify risk of advanced ..
  54. EARLY HUSBANDRY INFLUENCES ON ADULT PHENOTYPE
    MICHAEL TORDOFF; Fiscal Year: 2009
    ..The results will lead to better environmental controls in future work and, asa direct consequence, easierand more rapid progress with genetic analyses. ..
  55. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2006
    ..This study will evaluate calcium/dairy as a modulator of energy balance, important to the management of body fat in children. ..
  56. CALCIUM METABOLISM IN ASIAN GIRLS AND POSTMENOPAUSAL WOMEN
    Connie Weaver; Fiscal Year: 2006
    ..Optimizing calcium retention during periods of rapid growth is a key nutritional strategy to build peak bone mass and reduce lifelong risk of osteoporosis. ..
  57. 24,25-DIHYDROXYVITAMIN D: MARKER OF SALT SENSITIVITY
    Connie Weaver; Fiscal Year: 2001
    ..averages 423 mg/day during the period of rapid skeletal accretion in white adolescent girls at a mean dietary calcium intake of 1300 mg/day. Urinary calcium explains more than 50% of the variance in calcium retention...
  58. Calcium Absorption and Bone Formation During Puberty
    Steven Abrams; Fiscal Year: 2005
    ..and V0+; 3) The addition of NDO will increase Ca-abs and Vo+ in pubertal children receiving recommended dietary calcium intakes...
  59. Novel Risk Factors for Kidney Stone Formation
    Eric Taylor; Fiscal Year: 2008
    ..At the completion of this career development award, Dr. Taylor will have a unique combination of skills and experience that will enable him to succeed as an independent clinical investigator. ..
  60. DIET SALT, CALCIUM KIDNEY STONES, BONE IN STONE FORMERS
    Linda Massey; Fiscal Year: 2001
    ..Reduction of dietary NaC1 from typical intakes of 200 mmol/day to an intake of 50 mmol/day may decrease the risk of recurrence of calcium-containing kidney stones and slow rates of bone loss, thus reducing risk of osteoporosis as well. ..
  61. EFFECTS OF ACID ON BONE
    David A Bushinsky; Fiscal Year: 2010
    ..The current proposal is aimed at understanding the first steps by which acid is detected by bone cells. Understanding the process by which the bone detects and neutralizes the acid can lead to an improvement in bone health. ..