nicarbazin

Summary

Summary: An equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.

Top Publications

  1. ncbi Coccidiosis control with toltrazuril in conjunction with anticoccidial medicated or nonmedicated feed
    G F Mathis
    Southern Poultry Research, Inc, 2011 Brock Road, Athens, GA 30607, USA
    Avian Dis 47:463-9. 2003
  2. ncbi Survey of the anticoccidial feed additive nicarbazin (as dinitrocarbanilide residues) in poultry and eggs
    Martin Danaher
    Food Safety Department, Ashtown Food Research Centre, Ashtown, Dublin 15, Ireland
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:32-40. 2008
  3. ncbi [Simple determination of residual anticoccidial drugs (diclazuril and nicarbazin) in chicken tissues by HPLC]
    Maki Kanda
    Tokyo Metropolitan Research Laboratory of Public Health 3 24 1, Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
    Shokuhin Eiseigaku Zasshi 44:110-3. 2003
  4. ncbi Coccidiosis control by administering toltrazuril in the drinking water for a 2-day period
    G F Mathis
    Southern Poultry Research Inc, 2011 Brock Road, Athens, GA 30607, USA
    Vet Parasitol 121:1-9. 2004
  5. ncbi Efficient HPLC method for the determination of nicarbazin, as dinitrocarbanilide in broiler liver
    Emiliana Capurro
    Teagasc, The National Food Centre, Dunsinea, Ashtown, Dublin 15, Ireland
    J Chromatogr B Analyt Technol Biomed Life Sci 822:154-9. 2005
  6. ncbi An all-in-one dry chemistry immunoassay for the screening of coccidiostat nicarbazin in poultry eggs and liver
    Virve Hagren
    Department of Biotechnology, University of Turku, Tykistokatu 6A, FIN 20520 Turku, Finland
    J Agric Food Chem 52:2429-33. 2004
  7. ncbi Investigation of the causes for the occurrence of residues of the anticoccidial feed additive nicarbazin in commercial poultry
    M O'Keeffe
    Food Safety Department, Ashtown Food Research Centre, Ashtown, Dublin 15, Ireland
    Food Addit Contam 24:923-34. 2007
  8. ncbi Development and validation of a lateral flow device for the detection of nicarbazin contamination in poultry feeds
    Katrina Campbell
    Institute of Agri food and Land Use, Queen s University, David Keir Building, Stranmillis Road, Belfast BT9 5AG, UK
    J Agric Food Chem 55:2497-503. 2007
  9. ncbi The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics
    Lisa Connolly
    Veterinary Sciences Division, Department of Agriculture and Rural Development for Northern Ireland, Stoney Road, Northern Ireland, Belfast, UK
    J Immunol Methods 264:45-51. 2002
  10. ncbi Poly(methyl methacrylate) synthetic grit formulations sustain the delivery of nicarbazin, a contraceptive agent, in pest waterfowl
    Jerome C Hurley
    USDA, APHIS, Wildlife Services, National Wildlife Research Center, 4101 La Porte Avenue, Fort Collins, CO 80521, USA
    J Control Release 85:135-43. 2002

Scientific Experts

Detail Information

Publications104 found, 100 shown here

  1. ncbi Coccidiosis control with toltrazuril in conjunction with anticoccidial medicated or nonmedicated feed
    G F Mathis
    Southern Poultry Research, Inc, 2011 Brock Road, Athens, GA 30607, USA
    Avian Dis 47:463-9. 2003
    ..The treatments were 125 ppm nicarbazin (days 0-14) to 66 ppm salinomycin (SAL) (days 15-35) with and without toltrazuril, SAL (days 0-35) with and ..
  2. ncbi Survey of the anticoccidial feed additive nicarbazin (as dinitrocarbanilide residues) in poultry and eggs
    Martin Danaher
    Food Safety Department, Ashtown Food Research Centre, Ashtown, Dublin 15, Ireland
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:32-40. 2008
    A survey was carried out on the occurrence of dinitrocarbanilide (DNC), the marker residue for nicarbazin, in poultry produced in Ireland during 2002-2004. Liver (n = 736) and breast muscle samples (n = 342) were tested...
  3. ncbi [Simple determination of residual anticoccidial drugs (diclazuril and nicarbazin) in chicken tissues by HPLC]
    Maki Kanda
    Tokyo Metropolitan Research Laboratory of Public Health 3 24 1, Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
    Shokuhin Eiseigaku Zasshi 44:110-3. 2003
    A simple and rapid determination of anticoccidial drug residues, diclazuril (DCZ) and nicarbazin (NCZ), in chicken tissues has been developed. DCZ and NCZ were extracted with acetonitrile from chicken liver, muscle, and fat...
  4. ncbi Coccidiosis control by administering toltrazuril in the drinking water for a 2-day period
    G F Mathis
    Southern Poultry Research Inc, 2011 Brock Road, Athens, GA 30607, USA
    Vet Parasitol 121:1-9. 2004
    ....
  5. ncbi Efficient HPLC method for the determination of nicarbazin, as dinitrocarbanilide in broiler liver
    Emiliana Capurro
    Teagasc, The National Food Centre, Dunsinea, Ashtown, Dublin 15, Ireland
    J Chromatogr B Analyt Technol Biomed Life Sci 822:154-9. 2005
    ..The mean recovery was typically >70% and the limits of quantitation was 12.5 microg/kg (based on the lowest standard on the calibration curve)...
  6. ncbi An all-in-one dry chemistry immunoassay for the screening of coccidiostat nicarbazin in poultry eggs and liver
    Virve Hagren
    Department of Biotechnology, University of Turku, Tykistokatu 6A, FIN 20520 Turku, Finland
    J Agric Food Chem 52:2429-33. 2004
    An automated immunoassay for the detection of nicarbazin residues in poultry eggs and liver was developed. The assay was based on a novel all-in-one dry chemistry concept and time-resolved fluorometry...
  7. ncbi Investigation of the causes for the occurrence of residues of the anticoccidial feed additive nicarbazin in commercial poultry
    M O'Keeffe
    Food Safety Department, Ashtown Food Research Centre, Ashtown, Dublin 15, Ireland
    Food Addit Contam 24:923-34. 2007
    ..were undertaken to identify causes for the occurrence of high levels of the zootechnical feed additive nicarbazin in broiler liver at slaughter...
  8. ncbi Development and validation of a lateral flow device for the detection of nicarbazin contamination in poultry feeds
    Katrina Campbell
    Institute of Agri food and Land Use, Queen s University, David Keir Building, Stranmillis Road, Belfast BT9 5AG, UK
    J Agric Food Chem 55:2497-503. 2007
    Concentrations of the coccidiostat nicarbazin as low as 2 mg/kg in feed can result in violative drug residues arising in poultry liver...
  9. ncbi The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics
    Lisa Connolly
    Veterinary Sciences Division, Department of Agriculture and Rural Development for Northern Ireland, Stoney Road, Northern Ireland, Belfast, UK
    J Immunol Methods 264:45-51. 2002
    Polyclonal antibodies were produced to detect the coccidiostat nicarbazin. Due to structural constraints of the active component of nicarbazin, dinitrocarbanilide (DNC), three different compounds that shared a common substructure with DNC ..
  10. ncbi Poly(methyl methacrylate) synthetic grit formulations sustain the delivery of nicarbazin, a contraceptive agent, in pest waterfowl
    Jerome C Hurley
    USDA, APHIS, Wildlife Services, National Wildlife Research Center, 4101 La Porte Avenue, Fort Collins, CO 80521, USA
    J Control Release 85:135-43. 2002
    ..based synthetic grit formulations containing varying concentrations of a proposed wildlife contraceptive (nicarbazin), plasticizer (acetyl tributylcitrate) and/or cross-linking agent (1,4-butanediol diacrylate)...
  11. ncbi Comparison of nicarbazin absorption in chickens, mallards, and Canada geese
    C A Yoder
    National Wildlife Research Center, Fort Collins, Colorado 80521 2154, USA
    Poult Sci 84:1491-4. 2005
    b>Nicarbazin (NCZ), a coccidiostat commonly used in the poultry industry, causes reduced hatchability and egg quality in layer hens at a concentration of 125 ppm (8.4 mg/kg) in the feed...
  12. ncbi Evaluation of nicarbazin as a potential waterfowl contraceptive using mallards as a model
    C A Yoder
    National Wildlife Research Center, Fort Collins, CO 80521 2154, USA
    Poult Sci 85:1275-84. 2006
    ..We tested the efficacy of nicarbazin (NCZ) as a contraceptive for waterfowl and assessed health effects of NCZ, using domestic mallards (Anas ..
  13. ncbi The effect of cooking on veterinary drug residues in food: nicarbazin (dinitrocarbanilide component)
    J A Tarbin
    Central Science Laboratory, Sand Hutton, York, Y041 ILZ, UK
    Food Addit Contam 22:1126-31. 2005
    The change of concentration of residues of the marker compound for the anti-coccidial drug nicarbazin, N,N'-bis(4-nitrophenyl)urea (dinitrocarbanilide, DNC), was investigated in model oil and aqueous solutions and in chicken muscle and ..
  14. ncbi Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine
    G F Mathis
    Southern Poultry Research, Inc, 2011 Brock Road, Athens, GA 30607, USA
    Avian Dis 50:321-4. 2006
    ..Vaccination with the anticoccidial drug-sensitive strains produced a measurable increase in the level of sensitivity to diclazuril...
  15. ncbi Veterinary pharmaceuticals and antibiotic resistance of Escherichia coli isolates in poultry litter from commercial farms and controlled feeding trials
    V Furtula
    Aquatic Ecosystem Impacts Research Division, Pacific Environmental Science Centre, Environment Canada, 2645 Dollarton Highway, North Vancouver, British Columbia, Canada, V7H 1B1
    Poult Sci 89:180-8. 2010
    ..Feed additives bacitracin, chlortetracycline, monensin, narasin, nicarbazin, penicillin, salinomycin, and virginiamycin, which were present in the feed on commercial farms and added to the ..
  16. ncbi Comparison of ion-pairing and ion-suppressing liquid chromatographic methods for the determination of pyrimethamine and ormetoprim in chicken feed
    Shih Yuh Lin
    National Institute for Animal Health, Council of Agriculture, Tansui, Taipei, Taiwan
    J Chromatogr Sci 40:331-6. 2002
    ..Sulfamonomethoxine, sulfadimethoxine, sulfaquinoxaline, trimethoprim, amprolium, clopidol, and nicarbazin do not interfere with the detection of PYR or OMT...
  17. ncbi Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms
    B Lefebvre
    Centre d Étude et de Valorisation de la Diversité Microbienne CEVDM, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, 2500 Boulevard de Université, Sherbrooke, Quebec, Canada, J1K 2R1
    Poult Sci 88:1474-84. 2009
    ..used feed supplemented with different antimicrobial agents (virginiamycin, bacitracin, salinomycin, narasin, nicarbazin, or diclazuril)...
  18. ncbi Liquid chromatographic tandem mass spectrometric determination of five coccidiostats in poultry eggs and feed
    Leen Mortier
    Ministry of the Flemish Community, Agricultural Research Centre Ghent CLO, Department of Animal Product Quality and Transformation Technology DVK, Brusselsesteenweg 370, 9090 Melle, Belgium
    J Chromatogr B Analyt Technol Biomed Life Sci 820:261-270. 2005
    ..which permits the quantitative detection of the chemical coccidiostats halofuginone, robenidine, diclazuril, nicarbazin and dimetridazole and its main metabolite 2-hydroxydimetridazole in poultry eggs and feed...
  19. ncbi Chemotherapeutic approaches to protozoa: Coccidiae--current level of knowledge and outlook
    G Greif
    Animal Health Business Group, Research and Development, Biological and Chemical Evaluation, Bayer AG Monheim, Leverkusen, Germany
    Parasitol Res 87:973-5. 2001
    ..of older preparations which have not been used for a long time, the introduction of combinations such as narasin nicarbazin or methyl benzoquate clopidol and the alternating use of anticoccidial agents in rotation and shuttle programmes...
  20. ncbi The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity
    D A Ostlind
    Merck Research Laboratories, PO Box 2000, Rahway, New Jersey 07065, USA
    J Parasitol 90:898-9. 2004
    ..Rafoxanide (fasciolicide) was active at 25 mg/kg, the lowest level tested. The coccidiostat, nicarbazin, was active at experimental levels (800 mg/kg and up)...
  21. ncbi The production and characterisation of an antibody to detect the coccidiostat toltrazuril and its metabolite ponazuril
    Lisa Connolly
    Queens University Belfast, Veterinary Sciences Division, Stoney Road, Belfast, N Ireland, UK BT4 3SD
    Analyst 128:459-61. 2003
    ..toltrazuril sulfone) but does not cross-react with other coccidiostats such as halofuginone, nitroimidazoles or nicarbazin. This is the first reported production of an antibody capable of specifically binding toltrazuril and ponazuril.
  22. ncbi Liquid chromatographic determination and liquid chromatographic-thermospray mass spectrometric confirmation of nicarbazin in chicken tissues: interlaboratory study
    M G Leadbetter
    U S Food and Drug Administration, Center for Veterinary Medicine, Beltsville, MD 20705
    J AOAC Int 76:420-3. 1993
    ..sponsored an interlaboratory study of a liquid chromatographic determination with ultraviolet detection of nicarbazin in chicken liver and muscle tissues...
  23. ncbi Residual activity of anticoccidial drugs in chickens after withdrawal of medicated feeds
    L R McDougald
    Department of Poultry Science, University of Georgia, Athens 30602, USA
    Vet Parasitol 74:91-9. 1998
    Seven anticoccidial drugs commonly used in poultry (diclazuri), monensin, salinomycin, halofuginone, nicarbazin, robenidine, amprolium, and lasalocid) were tested for residual activity after withdrawal...
  24. ncbi Molecular effects of nicarbazin on avian reproduction
    C A Yoder
    National Wildlife Research Center, Fort Collins, Colorado 80521 2154, USA
    Poult Sci 85:1285-93. 2006
    b>Nicarbazin (NCZ) is an anticoccidial drug routinely used in the poultry industry that can negatively affect reproduction by reducing egg production, egg weight, and egg hatchability...
  25. ncbi Feed additives diclazuril and nicarbazin in egg and liver samples from Croatian farms
    Nina Bilandžić
    a Department of Veterinary Public Health, Laboratory for Residue Control, Croatian Veterinary Institute, Zagreb, Croatia
    Food Addit Contam Part B Surveill 6:90-7. 2013
    In total 307 egg and 275 liver samples were examined for nicarbazin and 365 eggs for diclazuril over a 30-month period...
  26. ncbi Comparison of three adjuvants used to produce polyclonal antibodies to veterinary drugs
    Terence L Fodey
    Agri Food and Biosciences Institute, Veterinary Sciences Division, Stoney Road, Belfast BT4 3SD, UK
    Vet Immunol Immunopathol 122:25-34. 2008
    ..It was concluded that Montanide ISA 50V could be considered as a suitable replacement to Freund's for the production of polyclonal antibodies, to low molecular weight compounds in rabbits...
  27. ncbi Use of anticoccidial drugs in broiler chickens in the USA: analysis for the years 1995 to 1999
    H D Chapman
    Department of Poultry Science, University of Arkansas, Fayetteville 72701, USA
    Poult Sci 80:572-80. 2001
    ..A chemical (principally nicarbazin) was also used in the starter feed followed by an ION in the grower feed, or two different ION in the starter ..
  28. ncbi High-performance liquid chromatography-based determination of nicarbazin excretion in waterfowl
    Randal S Stahl
    National Wildlife Research Center, USDA APHIS, 4101 La Porte Avenue, Fort Collins, CO 99801 USA
    J Chromatogr B Analyt Technol Biomed Life Sci 775:103-8. 2002
    A method for the high-performance liquid chromatography (HPLC) determination of nicarbazin uptake and excretion in ducks is presented...
  29. ncbi Selection for resistance to monensin, nicarbazin, and the monensin plus nicarbazin combination
    K W Bafundo
    Lilly Research Laboratories, A Division of Eli Lilly and Company, Greenfield, Indiana 46140
    Poult Sci 69:1485-90. 1990
    ..relative ability of strains of Eimeria acervulina and Eimeria tenella to develop resistance to monensin (MON), nicarbazin (NIC), and the monensin plus nicarbazin combination (MON plus NIC)...
  30. ncbi Determination of nicarbazin in chicken tissues by liquid chromatography and confirmation of identity by thermospray liquid chromatography/mass spectrometry
    J L Lewis
    Lilly Research Laboratories, Division of Eli Lilly and Co, Greenfield, IN 46140 0708
    J Assoc Off Anal Chem 72:577-81. 1989
    A liquid chromatographic method is described for the quantitative measurement of nicarbazin in chicken liver, fat, muscle, and skin tissues...
  31. ncbi The political and social barriers for contraception in pest birds: a case study of Ovocontrol (nicarbazin)
    Alexander MacDonald
    Innolytics, LLC, Rancho Santa Fe, California 92067, USA
    J Zoo Wildl Med 44:S132-4. 2013
    ..and Plant Health Inspection Service National Wildlife Research Center collaborated in the development of nicarbazin as an avian contraceptive, initially for resident Canada geese and subsequently for feral pigeons...
  32. ncbi A novel ion-pairing chromatographic method for the simultaneous determination of both nicarbazin components in feed additives: chemometric tools for improving the optimization and validation
    María M De Zan
    Laboratorio de Control de Calidad de Medicamentos, Cátedra de Química Analítica I, Facultad de Bioquimica y Ciencias Biologicas, Universidad Nacional del Litoral, C C 242, S3000ZAA Santa Fe, Argentina
    Talanta 85:142-50. 2011
    ..of an ion-pairing high performance liquid chromatography method for the simultaneous determination of both nicarbazin (NIC) components: 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP) in bulk materials and ..
  33. ncbi Determination of 20 coccidiostats in milk, duck muscle and non-avian muscle tissue using UHPLC-MS/MS
    L Clarke
    Food Safety Department, Teagasc Food Research Centre, Ashtown, Dublin, Ireland
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:958-69. 2013
    ..diaveridine, ethopabate, halofuginone, laidlomycin, lasalocid, maduramicin, monensin, narasin, nequinate, nicarbazin, robenidine, salinomycin, semduramicin, toltrazuril, toltrazuril sulphoxide and toltrazuril sulphone) in muscle ..
  34. ncbi The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites
    R W Gerhold
    Department of Poultry Science, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 55:59-64. 2011
    ..125 ppm), diclazuril (1 ppm and 2 ppm), decoquinate (30 ppm), lasalocid (120 ppm), monensin (90 ppm), narasin/nicarbazin (36/36 ppm), robenidine (33 ppm), roxarsone (50 ppm), sulfadimethoxine/ ormetoprin (125/75 ppm), salinomycin (60 ..
  35. ncbi A comparison of three continuous and four shuttle anticoccidial programs
    J R Guneratne
    Lilly Research Laboratories, A Division of Eli Lilly and Company, Greenfield, Indiana 46140
    Poult Sci 70:1888-94. 1991
    Continuous programs of a combination of narasin (40 ppm) and nicarbazin (40 ppm) (NaNi), narasin at levels of 60 and 70 ppm, and a 2 by 2 factorial shuttle design (NaNi or nicarbazin at 125 ppm, each for 27 or 28 days, followed by narasin ..
  36. ncbi The effects of combining Artemisia annua and Curcuma longa ethanolic extracts in broilers challenged with infective oocysts of Eimeria acervulina and E. maxima
    Gustavo F D Almeida
    Department of Agroecology, Faculty of Sciences and Technology, Aarhus University, Research Centre Foulum, Blichers alle 20, P O Box 50, DK 8830 Tjele, Denmark
    Parasitology 141:347-55. 2014
    ..with a negative control (uninfected), a positive control (infected and untreated), chemical coccidiostats (nicarbazin+narazin and, later, salinomycin), vaccination, and a product based on oregano...
  37. ncbi Residues of veterinary medicinal products and coccidiostats in eggs--causes, control and results of surveillance program in Poland
    M Piatkowska
    Department of Pharmacology and Toxicology, National Veterinary Research Institute, al Partyzantow 57, 24 100 Pulawy, Poland
    Pol J Vet Sci 15:803-12. 2012
    ..The most often determined coccidiostats were: nicarbazin, dinitrocarbanilide, salinomycin and lasalocid, and the most often reported non-compliant results for veterinary ..
  38. ncbi Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24
    Thomas J Burnett
    Elanco Animal Health, 2500 Innovation Way, Greenfield, IN 46140, USA
    J AOAC Int 95:959-91. 2012
    ..and selectivity of the method for narasin and monensin in the presence of lasalocid, salinomycin, maduramycin, nicarbazin, and sulfadiazine. Recoveries varied from 86.2 to 103.5% for narasin and 89.1 to 105.1% for monensin...
  39. ncbi Multi-residue method for detecting coccidiostats at carry-over level in feed by HPLC-MS/MS
    Ph Delahaut
    CER Groupe, Division Hormonologie, Rue du Point du Jour, 8 6900 Marloie, Belgium
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 27:801-9. 2010
    ..sodium, maduramicin ammonium alpha, robenidine hydrochloride, decoquinate, halofuginone hydrobromide, nicarbazin, and diclazuril) in feedstuffs at carry-over level...
  40. ncbi Sensitivity of Escherichia coli O157:H7 strain 932 to selected anticoccidial drugs in broiler chicks
    V G Stanley
    Cooperative Agricultural Research Center, Prairie View A and M University, Texas 77446, USA
    Poult Sci 75:42-6. 1996
    ..coli O157:H7 on Day 1, and fed diets supplemented with three selected anticoccidial drugs; monensin, nicarbazin, or robenidine...
  41. ncbi Response of 21 Canadian field isolates of chicken coccidia to commercial anticoccidial drugs
    A Rotibi
    Department of Poultry Science, University of Georgia, Athens 30602
    Avian Dis 33:365-7. 1989
    ..judged sensitive to amprolium, 5 to monensin, 9 to salinomycin, 14 to lasalocid, 19 to halofuginone, and 20 to nicarbazin. Similar trends in sensitivity/tolerance were identified from the percent reduction of intestinal lesion scores ..
  42. ncbi Risk assessment of coccidostatics during feed cross-contamination: animal and human health aspects
    J L C M Dorne
    European Food Safety Authority, Unit on Contaminants in the Food Chain, Parma, Italy
    Toxicol Appl Pharmacol 270:196-208. 2013
    ..sodium, salinomycin, narasin, maduramicin and semduramicin) or non-ionophoric (robenidine, decoquinate, nicarbazin, diclazuril, and halofuginone) substances...
  43. ncbi Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001
    H W Peek
    Animal Health Service, Poultry Health Centre, P O Box 9, 7400 AA Deventer, The Netherlands
    Avian Pathol 32:391-401. 2003
    ..The selected anticoccidial drugs were monensin, narasin, salinomycin, lasalocid, nicarbazin, diclazuril, halofuginone, maduramicin and meticlorpindol/methylbenzoquate...
  44. ncbi Can the use of coccidiostats in poultry breeding lead to residues in vegetables? An experimental study
    N Broekaert
    Department of Bioanalysis, Ghent University, Gent, Belgium
    J Agric Food Chem 60:12411-8. 2012
    ..feed containing the maximum allowed level of a coccidiostat: monensin, lasalocid A, salinomycin, diclazuril, and nicarbazin/narasin, plus one control group...
  45. ncbi The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS)
    Dharmendr K Matabudul
    Veterinary Drugs Group, LGC, Teddington, Middlesex, UK
    Analyst 127:760-8. 2002
    ..for the simultaneous extraction and determination of five of the most commonly used anticoccidial drugs (nicarbazin, lasalocid, monensin, narasin and salinomycin) from livers and eggs by LC-MS-MS...
  46. pmc Development of a five-plex flow cytometric immunoassay for the simultaneous detection of six coccidiostats in feed and eggs
    Monique E Bienenmann-Ploum
    RIKILT Institute of Food Safety, Wageningen UR, Wageningen, The Netherlands
    Anal Bioanal Chem 404:1361-73. 2012
    ..the levels set by the EU as the measured limits of detection for narasin/salinomycin, lasalocid, diclazuril, nicarbazin (4,4'-dinitrocarbanilide) and monensin in eggs were 0.01, 0.1, 0.5, 53 and 0.1 μg/kg and in feed 0.1, 0.2, 0...
  47. ncbi Development and validation of a method for the confirmation of nicarbazin in chicken liver and eggs using LC-electrospray MS-MS according to the revised EU criteria for veterinary drug residue analysis
    S Yakkundi
    Queen s University Belfast, Department of Veterinary Science, Northern Ireland, UK
    Analyst 126:1985-9. 2001
    A method is described for the quantitative confirmation of 4,4'-dinitrocarbanilide (DNC), the marker residue for nicarbazin in chicken liver and eggs...
  48. ncbi Sensitivity of Eimeria field isolates in the United States: responses of nicarbazin-containing anticoccidials
    K W Bafundo
    Phibro Animal Health Corporation, Ridgefield Park, NJ 07660, USA
    Poult Sci 87:1760-7. 2008
    ..were conducted to assess the drug sensitivity of 26 coccidial field isolates to the anticoccidial effects of nicarbazin (NIC) and narasin + NIC (NAR + NIC)...
  49. ncbi Deposition and depletion of five anticoccidials in eggs
    Leen Mortier
    Ministry of the Flemish Community, Agricultural Research Centre Ghent CLO, Department of Animal Product Quality and Transformation Technology DVK, Brusselsesteenweg 370, 9090 Melle, Belgium
    J Agric Food Chem 53:7142-9. 2005
    ..For the compounds diclazuril, robenidine, halofuginone and nicarbazin in combination with narasin, two concentration levels were tested: the maximum allowed concentration for ..
  50. ncbi Determination of veterinary pharmaceuticals in poultry litter and soil by methanol extraction and liquid chromatography-tandem mass spectrometry
    Vesna Furtula
    Pacific Environmental Science Centre, Environment Canada, North Vancouver, British Columbia, Canada
    J Environ Sci Health B 44:717-23. 2009
    ..method was developed for determination of the antimicrobials virginiamycin, monensin, salinomycin, narasin and nicarbazin in poultry litter and soil...
  51. ncbi Effect of method of delivering nicarbazin to mallards on plasma 4,4'-dinitrocarbanilide levels and reproduction
    C A Yoder
    National Wildlife Research Center, Fort Collins, CO 80521, USA
    Poult Sci 85:1442-8. 2006
    b>Nicarbazin (NCZ), a coccidiostat used in the poultry industry, has been developed as a contraceptive for resident Canada geese...
  52. ncbi Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry
    Małgorzata Olejnik
    Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24 100 Pulawy, Poland
    J Chromatogr A 1216:8141-8. 2009
    ..narasin, salinomycin, semduramycin) and chemical coccidiostats (clazuril, decoquinate, diclazuril, halofuginone, nicarbazin and robenidine) in poultry liver has been developed...
  53. ncbi Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC
    Estelle Dubreil-Chéneau
    Veterinary Drug Residues Unit, Laboratory for the Research and Investigation of Veterinary Drugs and Disinfectants, AFSSA Fougeres, BP 90203 La Haute Marche, 35133 Javene, France
    J Chromatogr A 1216:8149-57. 2009
    ..LC-MS/MS) method for the simultaneous detection and confirmation of halofuginone, robenidine, diclazuril, nicarbazin, monensin, narasin, lasalocid, salinomycin, maduramicin and semduramicin in whole egg has been developed and ..
  54. ncbi The effect of commonly used anticoccidials and antibiotics in a subclinical necrotic enteritis model
    A Lanckriet
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Avian Pathol 39:63-8. 2010
    ..The ionophore anticoccidials lasalocid, salinomycin, maduramicin, narasin and a combination of narasin and nicarbazin were tested in feed for their prophylactic effect on the incidence of necrotic enteritis in a subclinical ..
  55. ncbi Fate and antibacterial potency of anticoccidial drugs and their main abiotic degradation products
    Martin Hansen
    Section of Toxicology and Environmental Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK 2100 Copenhagen, Denmark
    Environ Pollut 157:474-80. 2009
    ..4 and 19.6 microM were obtained; however, one compound, nicarbazin exhibited an EC(50)-value above the maximum tested concentration (21 microM, 9.1 mg L(-1))...
  56. ncbi Review of issues concerning the use of reproductive inhibitors, with particular emphasis on resolving human-wildlife conflicts in North America
    Kathleen A Fagerstone
    US Department of Agriculture Animal and Plant Health Inspection Service Wildlife Services, National Wildlife Research Center, Fort Collins, CO 80521 2154, USA
    Integr Zool 5:15-30. 2010
    ..Two fertility control agents, an avian reproductive inhibitor containing the active ingredient nicarbazin and an immunocontraceptive vaccine, have received regulatory approval with the Environmental Protection Agency ..
  57. ncbi A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS
    Jasna Dmitrovic
    Canadian Food Inspection Agency, Calgary Laboratory, 3650 36 St NW, Calgary, AB T2L 2L1, Canada
    J AOAC Int 94:428-35. 2011
    An HPLC/MS/MS method has been developed and validated for the quantification and confirmation of nicarbazin and ionophores (lasalocid, monensin, salinomycin, and narasin) in eggs...
  58. ncbi Fast liquid chromatography/multiple-stage mass spectrometry of coccidiostats
    Anna Martínez-Villalba
    Department of Analytical Chemistry, Unversity of Barcelona, Av Diagonal 647, E 08028 Barcelona, Spain
    Rapid Commun Mass Spectrom 23:1255-63. 2009
    ..spectrometry to analyze eight coccidiostatic compounds: diclazuril, dinitrocarbanilide (the main metabolite of nicarbazin), robenidine, lasalocid, monensin, salinomycin, maduramicin and nasarin...
  59. ncbi Determination of acidic herbicides in cereals by QuEChERS extraction and LC/MS/MS
    Angela Santilio
    Department of Environmental and Primary Prevention, National Institute of Health, Rome, Italy
    J Environ Sci Health B 46:535-43. 2011
    ..Quantitative analysis was carried out by the internal standard (Nicarbazin) and the LC/MS/MS analysis was performed in electrospray ionisation (ESI) negative mode using a Zorbax XCB ..
  60. ncbi Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels
    Mark Cronly
    School of Pharmaceutical and Chemical Sciences, Dublin Institute of Technology, Dublin, Ireland
    Anal Chim Acta 700:26-33. 2011
    ..The method can be used to determine halofuginone, robenidine, nicarbazin, diclazuril, decoquinate, semduramicin, lasalocid, monensin, salinomycin, narasin, maduramicin at levels ..
  61. ncbi Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs
    Roberta Galarini
    Department of Food Safety, Istituto Zooprofilattico Sperimentale dell Umbria e delle Marche, Perugia, Italy
    Anal Chim Acta 700:167-76. 2011
    ..monensin, narasin, salinomycin, semduramycin and chemical coccidiostats: decoquinate, diclazuril, halofuginone, nicarbazin and robenidine in poultry eggs was developed and validated...
  62. ncbi Development and validation of an UPLC-MS/MS method for the determination of ionophoric and synthetic coccidiostats in vegetables
    N Broekaert
    Department of Bioanalysis, Laboratory of Food Analysis, Ghent University, Ghent, Belgium
    Anal Bioanal Chem 401:3335-44. 2011
    ..at 100 μg kg(-1) (dry weight) with coccidiostats (monensin, narasin, lasalocid A, salinomycin, diclazuril, and nicarbazin) in order to optimize the extraction and clean-up. Possible critical factors (e.g...
  63. ncbi Incidence of residues of nine anticoccidials in eggs
    L Mortier
    Department of Animal Product Quality and Transformation Technology DVK, Agricultural Research Centre Ghent CLO, Ministry of the Flemish Community, Brusselsesteenweg 370, B 9090 Melle, Belgium
    Food Addit Contam 22:1120-5. 2005
    ..were analysed for the presence of nine different compounds: dimetridazole, diclazuril, halofuginone, robenidine, nicarbazin, narasin, salinomycin, lasalocid and monensin. Analyses were performed by LC-MS/MS...
  64. ncbi Influence of coccidiosis on Salmonella colonization in broiler chickens under floor-pen conditions
    A Arakawa
    Department of Veterinary Medicine, College of Agriculture, University of Osaka Prefecture, Japan
    Poult Sci 71:59-63. 1992
    ..Chickens of two groups, unmedicated and medicated with nicarbazin (125 ppm via the feed), were exposed to three species of Eimeria (Eimeria tenella, Eimeria maxima, and Eimeria ..
  65. ncbi [Coccidiosis in broiler chicks: the prevalence of oocysts in feces in relation to necropsy findings in (sub)clinical coccidiosis and the effect of nicarbazin on these findings]
    W W Braunius
    Gezondheidsdienst voor Dieren in Gelderland, Velp
    Tijdschr Diergeneeskd 113:132-40. 1988
    ..Treatment with nicarbazin during te first three weeks of life was found to delay the appearance of coccidiosis...
  66. ncbi Anticoccidial activity of combinations of narasin and nicarbazin
    P L Long
    Department of Poultry Science, University of Georgia, Athens 30602
    Poult Sci 67:248-52. 1988
    The efficacy of mixtures of narasin and nicarbazin were evaluated by comparing broiler performance, susceptibility to heat stress, and the mode of action against Eimeria...
  67. ncbi Rapid procedure for determination of nicarbazin residues in chicken tissues
    O W Parks
    U S Department of Agriculture, Eastern Regional Research Center, Philadelphia, PA 19118
    J Assoc Off Anal Chem 71:778-80. 1988
    A procedure is described for the quantitation of nicarbazin residues in chicken tissues. The method includes extraction of tissue with chloroform-ethyl acetate-dimethyl sulfoxide (50 + 50 + 0...
  68. ncbi [The determination of the coccidiostat nicarbazin in animal tissue and eggs. I. Determination by pulse polarography and high pressure fluid chromatography with electrochemical detection]
    G Knupp
    Landesveterinäruntersuchungsamt Rheinland Pfalz, Koblenz, Bundesrepublik Deutschland
    Z Lebensm Unters Forsch 185:472-6. 1987
    The determination of nicarbazin residues in foodstuffs of animal origin by two different methods, polarography, HPLC with electrochemical detection, is described...
  69. ncbi Processing yields and meat flavor of broilers fed a mixture of narasin and nicarbazin as an anticoccidial agent
    I C Peng
    Department of Food Science, Purdue University, West Lafayette, Indiana 47907
    Poult Sci 66:1341-5. 1987
    ..and cooked meat flavor of broilers fed 100 ppm of an anticoccidial agent (a mixture of 50 ppm narasin and 50 ppm nicarbazin) were compared with yields of birds fed a ration without the anticoccidial agent...
  70. ncbi Nicarbazin effects on broiler thermobalance during high ambient temperature stress
    C J Wiernusz
    Department of Animal Science, Oklahoma State University, Stillwater 74078, USA
    Poult Sci 74:577-80. 1995
    Two experiments were conducted to measure the effects of nicarbazin (125 ppm) on heat production (H), evaporative heat loss (E), sensible heat loss (S), and heat content change (HC) of broilers during heat stress...
  71. ncbi A reverse-phase high-performance liquid chromatographic determination of nicarbazin residues in eggs
    F Kondo
    Department of Veterinary Public Health, Faculty of Agriculture, Miyazaki University, Japan
    Cytobios 76:175-82. 1993
    A reverse-phase high-performance liquid chromatographic (HPLC) method was employed for analysis of nicarbazin [1:1 mixture of 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4, 6-dimethyl-pyrimidine] in chicken eggs...
  72. ncbi Nicarbazin stimulates intestinal transport of L-leucine in rabbit
    V Sorribas
    Departmento de Fisiología y Farmacología, Universidad de Zaragoza, Facultad de Veterinaria, Spain
    J Vet Pharmacol Ther 16:32-7. 1993
    b>Nicarbazin is an anticoccidial drug used mainly in birds, but also in rabbits...
  73. ncbi Effect of nicarbazin and narasin-nicarbazin combinations on broiler pigmentation
    K W Bafundo
    Lilly Research Laboratories, Eli Lily and Company, Greenfield, Indiana 46140
    Poult Sci 68:374-9. 1989
    An experiment was conducted with young battery-reared chickens to evaluate the effects of graded levels of nicarbazin (0, 40, 80, 120, and 160 ppm) on plasma pigmentation in the presence and absence of coccidial infection...
  74. ncbi Lack of effect of dietary factors on nicarbazin toxicity in broiler chicks
    I Bartov
    Department of Poultry Science, Agricultural Research Organization, Volcani Center, Bet Dagan, Israel
    Poult Sci 68:145-52. 1989
    Effects of dietary fat, protein, and methionine levels and the type of dietary grain in nicarbazin-containing diets on the growth response of broiler chicks were evaluated in five experiments in a factorial design...
  75. ncbi Lack of interactive effect of nicarbazin and dietary energy-to-protein ratio on performance and abdominal fat pad weight of broiler chicks
    I Bartov
    Department of Poultry Science, The Volcani Center, Bet Dagan, Israel
    Poult Sci 68:1535-9. 1989
    ..170 from 8 to 28 days of age and 140 vs. 190 from 28 to 49 days of age) and nicarbazin supplementation (0 vs. 125 mg/kg) on performance and fattening...
  76. ncbi Research note: immunity to Eimeria in broilers reared on nicarbazin and salinomycin
    H D Chapman
    Department of Animal and Poultry Sciences, University of Arkansas, Fayetteville 72701
    Poult Sci 71:577-80. 1992
    ..in the litter at two broiler farms where birds were reared to 8 wk of age using a shuttle program involving nicarbazin (from 0 to 21 days of age) and salinomycin (from 21 to 44 days of age)...
  77. ncbi Increased skin tearing in broilers and reduced collagen synthesis in skin in vivo and in vitro in response to the coccidiostat halofuginone
    I Granot
    Institute of Animal Science, Agricultural Research Organization, Volcani Center, Bet Dagan, Isreal
    Poult Sci 70:1559-63. 1991
    ..The cultured cells were incubated with various concentrations of halofuginone, monensin, and nicarbazin, and [3H]proline incorporation was evaluated in collagenase-digestible (representing mostly collagen) and ..
  78. ncbi Research note: Maxiban effects on heat-distressed broiler growth rate and feed efficiency
    C J Wiernusz
    Animal Science Department, Oklahoma State University, Stillwater 74078
    Poult Sci 70:2207-9. 1991
    One study was conducted utilizing 192 male broilers, at 4 to 7 wk posthatching, to evaluate a narasin-nicarbazin drug combination (Maxiban) for effects on bird growth rate, feed efficiency, and survivability during cycling ambient ..
  79. ncbi Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts
    A Arakawa
    Department of Veterinary Science, College of Agriculture, University of Osaka Prefecture, Japan
    Vet Parasitol 38:55-60. 1991
    ..salinomycin, lasalocid, amprolium plus ethpabate, amporolium plus ethopabate plus sulfaquinoxaline, clopidol, or nicarbazin were given to chickens continuously via the feed at the recommended use level or one-half of that level...
  80. ncbi Effects of exposing broiler breeders to nicarbazin contaminated feed
    B L Hughes
    Department of Poultry Science, Clemson University, Clemson, South Carolina 29634 0379
    Poult Sci 70:476-82. 1991
    Ten-mo-old broiler feeds were fed nicarbazin (NCZ) at 0, 25, 50 and 100 ppm of their diet for 2, 4, or 6 days to simulate accidental contamination of their feed with the medicant...
  81. ncbi Efficacy of toltrazuril in broilers and development of a laboratory model for sensitivity testing of Eimeria field isolates
    M H Vertommen
    Poultry Health Institute, Doorn, The Netherlands
    Vet Q 12:183-92. 1990
    ..Treated birds were fed a broiler ration without anticoccidials. The efficacy of Baycox was compared with the nicarbazin-salinomycin shuttle. It was concluded that Baycox retarded the onset of Eimeria infection for several weeks...
  82. ncbi Production and egg-quality responses of White Leghorn layers to anticoccidial agents
    J E Jones
    Poultry Science Department, Clemson University, South Carolina 29634 0379
    Poult Sci 69:378-87. 1990
    ..In Experiment 1, nicarbazin (NCZ) was fed at 0, 20, 50, and 100 ppm...
  83. ncbi Sensitivity of field isolates of Eimeria tenella to anticoccidial drugs in the chicken
    H D Chapman
    Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire
    Res Vet Sci 47:125-8. 1989
    ..All were sensitive to robenidine, 28 were sensitive to methyl benzoquate, 25 to clopidol and 21 to nicarbazin. Most isolates were resistant or partly resistant to amprolium and dinitolmide.
  84. ncbi Effects of nicarbazin on sugar intestinal absorption in rabbits
    V Sorribas
    Departamento de Fisiologia y Farmacologia, Universidad de Zaragoza, Facultad de Veterinaria, Spain
    Res Vet Sci 53:19-24. 1992
    b>Nicarbazin is an anticoccidial drug, used mainly in birds, which can also be used in rabbits. It has been shown to produce several effects, such as inhibition of growth and feed efficiency in poultry...
  85. ncbi Studies of resistance to anticoccidials in Eimeria field isolates and pure Eimeria strains
    B Stephen
    Institute of Parasitology, School of Veterinary Medicine, Hannover, Germany
    Vet Parasitol 69:19-29. 1997
    ..or complete resistance to maduramicin was found in 7 field isolates, to monensin in 6, to salinomycin in 5, to nicarbazin in 8, to halofuginone in 7, to robenidine and toltrazuril in 1, and to diclazuril in 2 field isolates...
  86. ncbi Contamination of animal feedingstuffs with nicarbazin: investigations in a feed mill
    J D G McEvoy
    Department of Agriculture and Rural Development for Northern Ireland, Chemical Surveillance Department, Veterinary Sciences Division, Stormont, Belfast BT4 3SD, UK
    Food Addit Contam 20:136-40. 2003
    Some mechanisms of nicarbazin contamination were investigated in a feed mill. Three sequential 3-tonne batches of nicarbazin-free feed were produced directly after a batch of nicarbazin-containing feed (125 mg kg(-1))...
  87. ncbi Alternative procedures for molt induction: practical aspects
    A Bar
    Institute of Animal Science, Agricultural Research Organization, The Volcani Center, Bet Dagan 50250, Israel
    Poult Sci 82:543-50. 2003
    ..Ten days of feeding of a diet containing 0.06% nicarbazin (NICR) arrested egg production and caused a 22-d rest period but not a typical molt...
  88. ncbi Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss
    Andrew P Shinn
    Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, United Kingdom
    Dis Aquat Organ 55:17-22. 2003
    ..6 and 32.2% for amprolium, 20.1% for clopidol and 80.2, 71.9 and 93.3% respectively for salinomycin sodium...
  89. ncbi 4,4'-Dinitrocarbanilide (DNC) concentrations in egg shells as a predictor of nicarbazin consumption and DNC dose in goose eggs
    Randal S Stahl
    National Wildlife Research Center, 4101 LaPorte Ave, Ft Collins, CO 80521, USA
    Pest Manag Sci 59:1052-6. 2003
    b>Nicarbazin is being investigated as an infertility agent for the control of non-migratory Canada geese (Branta canadensis L) populations. Nicarbazin is presently registered for use as a coccidiostat for poultry...
  90. ncbi Liquid chromatographic determination of 4,4'-dinitrocarbanilide, the active component of the infertility agent nicarbazin, in chicken, duck, goose, and snake eggs
    Thomas M Primus
    US Department of Agriculture, Animal and Plant Health Inspection Service, National Wildlife Research Center, 4101 LaPorte Ave, Ft Collins, Denver, CO 80521, USA
    J AOAC Int 86:1144-8. 2003
    ..015 to 0.035 microg/g. The reported method is much simpler than and equally efficient as previous methods developed for the determination of DNC residues in egg contents...
  91. ncbi Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry
    M Dubois
    CER, Laboratoire d Hormonologie, Rue du Carmel 1, 6900 Marloie, Belgium
    J Chromatogr B Analyt Technol Biomed Life Sci 813:181-9. 2004
    ..and eggs the following nine coccidiostats: halofuginone, diclazuril, dinitrocarbanilide (the main metabolite of nicarbazin), robenidine, monensin, lasalocid, narasin, salinomycin, and maduramicin...
  92. ncbi Liquid chromatographic method for nicarbazin in broiler feeds and premixtures: development, validation, and interlaboratory study
    Jacob de Jong
    RIKILT Institute of Food Safety, Wageningen, The Netherlands
    J AOAC Int 87:1269-77. 2004
    A reversed-phase liquid chromatography method for nicarbazin in broiler feeds and premixtures was developed, validated, and interlaboratory studied. The extraction solvent was an acetonitrile-methanol (1 + 1) mixture...
  93. ncbi Determination of 4,4'-dinitrocarbanilide (DNC), a component of Nicarbazin, in Canada goose (Branta canadensis) eggshells using high-performance liquid chromatography
    Randal S Stahl
    USDA APHIS WS National Wildlife Research Center, 4101 LaPorte Avenue, Fort Collins, Colorado 80521, USA
    J Agric Food Chem 51:1130-5. 2003
    ..using high-performance liquid chromatography to assay 4,4'-dinitrocarbanilide (DNC), the active ingredient in Nicarbazin, in eggshells collected from Canada geese fed a formulated feed fortified with Nicarbazin at doses of 0, 125, ..
  94. ncbi Comparison of an attenuated anticoccidial vaccine and an anticoccidial drug programme in commercial broiler chickens in Italy
    R B Williams
    Schering Plough Animal Health, Breakspear Road South, Harefield, Uxbridge, Middlesex UB9 6LS, UK
    Avian Pathol 31:253-65. 2002
    A live attenuated anticoccidial vaccine (Paracox) was compared with a nicarbazin-monensin anticoccidial drug shuttle programme in three crops of Italian broilers, comprising a total of 290,405 chickens...
  95. ncbi Quantification of plasma and egg 4,4'-dinitrocarbanilide (DNC) residues for the efficient development of a nicarbazin-based contraceptive for pest waterfowl
    John J Johnston
    United States Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services, National Wildlife Research Center, 4101 LaPorte Avenue, Fort Collins, CO 80521, USA
    Pest Manag Sci 58:197-202. 2002
    ..program to develop socially acceptable techniques for management of pest bird populations, we are evaluating nicarbazin as a contraceptive in pest and surrogate avian species...
  96. ncbi Determination of nicarbazin in eggs by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
    W J Blanchflower
    Department of Agriculture for Northern Ireland, Veterinary Sciences Division, Belfast, UK
    J AOAC Int 80:1177-82. 1997
    ..in eggs 2 components [4,6-dimethyl-2-hydroxypyrimidine and 1,3-bis(4-nitrophenyl)urea] of the anticoccidial drug nicarbazin, used to treat poultry...
  97. ncbi Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials
    A Daugschies
    Institut für Parasitologie, Tierarztliche Hochschule Hannover, Germany
    Vet Parasitol 76:163-71. 1998
    ..The sensitivity profiles of the Eimeria spp. isolates against the anticoccidial drugs nicarbazin (NIC), narasin (NAR), halofuginone (HAL), salinomycin (SAL), meticlorpindol plus methylbenzoquate (MET), and ..
  98. ncbi Determination of nicarbazin in feeds using liquid chromatography-electrospray mass spectrometry
    A Cannavan
    Veterinary Sciences Division, Department of Agriculture for Northern Ireland, Stormont, Belfast, UK
    Analyst 124:1431-4. 1999
    A method is presented for the determination of the 4,4'-dinitrocarbanilide component of the coccidiostat nicarbazin in animal feeds...
  99. ncbi Liquid chromatographic determination of nicarbazin in feeds
    B J Krabel
    Elanco Animal Health, A Division of Eli Lilly and Company, Greenfield, IN 46140 0708, USA
    J AOAC Int 83:1027-38. 2000
    A new liquid chromatographic method has been developed for determination of nicarbazin in feeds. Approximately 40 g feed is extracted with 200 mL acetonitrile-water (80 + 20, v/v)...
  100. ncbi Nicarbazin contamination in feeds as a cause of residues in eggs
    A Cannavan
    Veterinary Sciences Division, Department of Agriculture and Rural Development, Stormont, Belfast, UK
    Food Addit Contam 17:829-36. 2000
    A survey was carried out to investigate the prevalence of nicarbazin residues in eggs in Northern Ireland. Nicarbazin, in the form of 4,4'-dinitrocarbanilide (DNC), was detected in 39 of the 190 eggs analysed...
  101. ncbi Possible causes of nicarbazin residues in chicken tissues
    A Cannavan
    Veterinary Sciences Division, Department of Agriculture and Rural Development, Stoney Road, Stormont, Belfast, BT4 3SD, UK
    Food Addit Contam 17:1001-6. 2000
    Two experiments were carried out to investigate possible causes of nicarbazin residues in broiler chicken tissues...