Summary: Vaccines used to prevent POLIOMYELITIS. They include inactivated (POLIOVIRUS VACCINE, INACTIVATED) and oral vaccines (POLIOVIRUS VACCINE, ORAL).
Publications172 found, 100 shown here
- The pathogenesis of poliomyelitis: what we don't knowNeal Nathanson
Department of Microbiology and Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Adv Virus Res 71:1-50. 2008..been eradicated while types 1 and 3 have not? (12) Can transmission of vaccine-derived polioviruses be prevented with inactivated poliovirus vaccine? (13) What is the best strategy to control and eliminate vaccine-derived polioviruses?..
- From emergence to eradication: the epidemiology of poliomyelitis deconstructedNeal Nathanson
Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Am J Epidemiol 172:1213-29. 2010..Beginning in 1955, the creation of poliovirus vaccines led to a stepwise reduction in poliomyelitis, culminating in the unpredicted elimination of wild ..
- The 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) coadministered with DTPw-HBV/Hib and poliovirus vaccines: assessment of immunogenicityNancy Bermal
Research Institute for Tropical Medicine, Filinvest Corporate City, Alabang, Muntinlupa City, The Philippines
Pediatr Infect Dis J 28:S89-96. 2009....
- Recombination between polioviruses and co-circulating Coxsackie A viruses: role in the emergence of pathogenic vaccine-derived poliovirusesSophie Jegouic
Institut Pasteur, Unité de Biologie des virus entériques, Paris, France
PLoS Pathog 5:e1000412. 2009....
- An outbreak of poliomyelitis caused by type 1 vaccine-derived poliovirus in ChinaXiaofeng Liang
National Immunization Programme, China Center for Disease Control and Prevention, Beijing, People s Republic of China, 100044
J Infect Dis 194:545-51. 2006..In May-July 2004, type 1 vaccine-derived poliovirus (VDPV) was isolated from 2 case patients with polio and a contact of a third case patient in Guizhou Province...
- Outbreak of type 2 vaccine-derived poliovirus in Nigeria: emergence and widespread circulation in an underimmunized populationSteven Wassilak
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 203:898-909. 2011..Strengthened routine immunization programs in countries with suboptimal coverage and balanced use of OPV formulations in SIAs are necessary to minimize risks of VDPV emergence and circulation...
- Protective efficacy of a monovalent oral type 1 poliovirus vaccine: a case-control studyNicholas C Grassly
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
Lancet 369:1356-62. 2007..A high-potency monovalent oral type 1 poliovirus vaccine (mOPV1) was developed in 2005 to tackle persistent poliovirus transmission in the last remaining infected countries. Our aim was to assess the efficacy of this vaccine in India...
- Transmission of imported vaccine-derived poliovirus in an undervaccinated community in MinnesotaJames P Alexander
National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 199:391-7. 2009..An investigation was conducted to determine the source of the virus and its means of transmission...
- [German Health survey 1997/98: immune status against poliomyelitis]S Diedrich
Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch Institut, Berlin
Dtsch Med Wochenschr 125:584-8. 2000..One of the goals of the WHO is the worldwide eradication of poliomyelitis in the next years. A high level of population immunity protects against imported wild viruses from endemic areas...
- Mucosal immunity and poliovirus vaccines: impact on wild poliovirus infection and transmissionHiromasa Okayasu
Polio Eradication Initiative, World Health Organization, Geneva, Switzerland
Vaccine 29:8205-14. 2011....
- Immunity status against poliomyelitis in Germany: determination of cut-off values in International UnitsSabine Diedrich
Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
BMC Infect Dis 2:2. 2002..Standard methodology for determination of polio antibodies is a feature aimed at obtaining consistent results. An International Standard Serum for polio antibodies exists, but no protective level in International Units is defined...
- Seroprevalence of antibodies to poliovirus in individuals living in Portugal, 2002M Pires de Miranda
Unidade de Vírus Respiratórios e Enterovirus, Instituto Nacional de Saude, Unit of Respiratory and Enteroviruses, National Health Institute, INS, Lisbon, Portugal
Euro Surveill 12:E7-8. 2007..For poliovirus type 3, the suboptimal antibody levels observed in teenagers and young adults suggest the need for a booster dose to minimise the risk of wild poliovirus importation...
- Primary vaccination of adults with reduced antigen-content diphtheria-tetanus-acellular pertussis or dTpa-inactivated poliovirus vaccines compared to diphtheria-tetanus-toxoid vaccinesHeidi Theeten
University of Antwerp, Universiteitsplein 1, Wilrijk, Belgium
Curr Med Res Opin 23:2729-39. 2007....
- Immunity to poliomyelitis in The NetherlandsM A Conyn-van Spaendonck
Department of Infectious Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Am J Epidemiol 153:207-14. 2001....
- [Regional variations of adult population vaccinal status]J Beytout
Service de Maladies Infectieuses, Hotel Dieu, Clermont Ferrand, France
Med Mal Infect 34:460-8. 2004..The authors had for aim to study the regional variations of vaccination coverage in adult population...
- Poliovirus detection in wastewater and stools following an immunization campaign in Havana, CubaPedro Mas Lago
Instituto de Medicina Tropical Pedro Kouri, Autopista Novia del Mediodia, Km 6, entre Autopista Nacional y Carretera Central, La Lisa, Havana City, Cuba
Int J Epidemiol 32:772-7. 2003..In this study, we evaluated the sensitivity of wastewater sampling by concurrently collecting stools from children aged < 3 years attending two neighbourhood clinics in Havana, Cuba, and wastewater from the same neighbourhoods...
- Poliovirus circulation among schoolchildren during the early phase of the 1992-1993 poliomyelitis outbreak in The NetherlandsP M Oostvogel
National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
J Infect Dis 184:1451-5. 2001..No evidence of vaccination was seen in 25.5%-43.1% of children at OR schools. Seroprevalence of antibodies against the 3 types of poliovirus suggested that no poliovirus circulation had occurred between the 1978 and 1992-1993 outbreaks...
- Polio eradication initiative in India: deconstructing the GPEIC Sathyamala
Centre of Social Medicine and Community Health, Jawaharlal Nehru University, New Delhi, India
Int J Health Serv 35:361-83. 2005..They conclude that the GPEI is yet another exercise in mismanaging the health priorities and programs in developing countries in the era of globalization...
- Rational design of genetically stable, live-attenuated poliovirus vaccines of all three serotypes: relevance to poliomyelitis eradicationAndrew J Macadam
NIBSC, South Mimms, Herts, UK
J Virol 80:8653-63. 2006....
- Low incidence of SV40-like sequences in ependymal tumoursF J Reuther
Department of Pathology, University Hospitals of Ulm, Ulm, Germany
J Pathol 195:580-5. 2001Between 1955 and 1963, millions of children and adults were exposed to SV40-contaminated poliovirus vaccines. The oncogenic potential of this polyomavirus was revealed when intracerebral inoculation of SV40 into newborn hamsters resulted ..
- Highly divergent neurovirulent vaccine-derived polioviruses of all three serotypes are recurrently detected in Finnish sewageM Roivainen
National Institute for Health and Welfare, Helsinki, Finland
Euro Surveill 15:pii/19566. 2010..While the source of the VDPV is unknown, characteristics of the viruses resemble those of strains isolated from immunodeficient, persistently infected persons. No cases of suspected poliomyelitis have been reported in Finland since 1985...
- Polio eradication in India: some observationsYash Paul
A D 7, Devi Marg, Bani Park, Jaipur 202016, India
Vaccine 22:4144-8. 2004..Vaccine failure has exaggerated the problem of VAPP. No efforts have been made to find the causes for high incidence of vaccine failure and VAPP...
- Surge in polio spreads alarm in northern Nigeria. Rumours about vaccine safety in Muslim-run states threaten WHO's eradication programmeClare Kapp
Lancet 362:1631-2. 2003
- Characterization of a rare natural intertypic type 2/type 3 penta-recombinant vaccine-derived poliovirus isolated from a child with acute flaccid paralysisYong Zhang
WHO WPRO Regional Polio Reference Laboratory and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No 27 Nanwei Road, Xuanwu District, Beijing 100050, PR China
J Gen Virol 91:421-9. 2010..This is the first report on the isolation of a type 2/type 3 poliovirus capsid recombinant with one of the five crossover sites located in the VP1 coding region...
- A case for developing antiviral drugs against polioMarc S Collett
ViroDefense Inc, 155 Gibbs Street, Suite 529, Rockville, MD 20850, United States
Antiviral Res 79:179-87. 2008..Given the timelines for eradication and those for drug development, the time for action is now...
- Recurrent isolation of poliovirus 3 strains with chimeric capsid protein Vp1 suggests a recombination hot-spot site in Vp1Soile Blomqvist
National Institute for Health and Welfare THL, Department of Infectious Disease Surveillance and Control, Intestinal Viruses Unit, P O Box 30, 00271 Helsinki, Finland
Virus Res 151:246-51. 2010..Our results suggest that there exists a PV3/PV2 recombination hot-spot site in the 3' partial region of the VP1 capsid protein and that the recombination may occur within weeks or a few months after the administration of OPV...
- Future of polio vaccinesEllie Ehrenfeld
National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA
Expert Rev Vaccines 8:899-905. 2009..Shifting factors in the risk-benefit-cost equation favor the creation of new poliovirus vaccines for use in the foreseeable future...
- Lack of serologic evidence for prevalent simian virus 40 infection in humansJoseph J Carter
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 95:1522-30. 2003Propagation of poliovirus in monkey kidney cells led to the inadvertent contamination of poliovirus vaccines with simian virus 40 (SV40) between 1955 and 1963...
- Successful co-administration of a human rotavirus and oral poliovirus vaccines in Bangladeshi infants in a 2-dose schedule at 12 and 16 weeks of ageK Zaman
International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, GPO Box 128, Mohakhali, Dhaka 1000, Bangladesh
Vaccine 27:1333-9. 2009..No statistically significant differences were observed between groups for polio seroprotection rates. RIX4414 vaccine was immunogenic when co-administered with OPV and did not interfere with OPV seroprotection rates...
- Multiplex PCR method for identifying recombinant vaccine-related poliovirusesDavid R Kilpatrick
Respiratory and Enteric Virus Branch, G 10, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 42:4313-5. 2004..Six pairs of Sabin strain-specific recombinant primers were designed to permit rapid screening for VDPV recombinants by PCR...
- One hundred years of poliovirus pathogenesisVincent R Racaniello
Department of Microbiology, Columbia University College of Physicians and Surgeons, 701 W 168th St, New York, NY 10032, USA
Virology 344:9-16. 2006..Nearly 50 years later, when two effective poliovirus vaccines were developed, the impetus to study poliovirus pathogenesis waned...
- Poliovirus vaccine strains detected in stool specimens of immunodeficient children in South AfricaDobromir N Pavlov
Department of Medical Virology, University of Pretoria NHLS, PO Box 2034, Pretoria 0001, South Africa
Diagn Microbiol Infect Dis 54:23-30. 2006..Therefore, the information obtained in this study would be essential for strategies aimed at the protection of both immunodeficient as well as immunocompetent individuals against complications of vaccination with OPV...
- Isolation and characterization of circulating type 1 vaccine-derived poliovirus from sewage and stream waters in HispaniolaJan Vinje
Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
J Infect Dis 189:1168-75. 2004..Our findings demonstrate a useful role for environmental surveillance of neurovirulent polioviruses in the overall polio eradication program...
- Poliovirus vaccine shedding among persons with HIV in Abidjan, Cote d'IvoireKaren A Hennessey
Global Immunization Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30309, USA
J Infect Dis 192:2124-8. 2005..The present study was conducted to assess whether persons infected with human immunodeficiency virus (HIV) experience prolonged VDPV shedding and serve as a source of reintroduction of virus into the population...
- Eradication versus control for poliomyelitis: an economic analysisKimberly M Thompson
Kids Risk Project, Harvard School of Public Health, Boston, MA 02115, USA
Lancet 369:1363-71. 2007..Challenges in the four endemic areas combined with continuing demands for financial resources for eradication have led some to question the goal of eradication and to suggest switching to a policy of control...
- Estimating the extent of vaccine-derived poliovirus infectionAlison Wringe
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England
PLoS ONE 3:e3433. 2008....
- Polio today: are we on the verge of global eradication?Stephen L Cochi
Centers for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Rd NE, Mailstop E 05, Atlanta, GA 30333, USA
JAMA 300:839-41. 2008
- [The German Health Interview and Examination Survey for Children and Adolescents (KiGGS): state of immunity against poliomyelitis in German children]S Diedrich
Robert Koch Institut, Berlin, BRD
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 50:771-4. 2007..The seroprevalence of antibodies against all three types of polioviruses indicates a very high level of population immunity in German children. It must be maintained through consequently performed vaccination programmes...
- Reemergence of recombinant vaccine-derived poliovirus outbreak in MadagascarMala Rakoto-Andrianarivelo
Unité de virologie, Institut Pasteur de Madagascar, Madagascar
J Infect Dis 197:1427-35. 2008..After the 2001-2002 poliomyelitis outbreak due to recombinant vaccine-derived polioviruses (VDPVs) in the Toliara province of Madagascar, another outbreak reoccurred in the same province in 2005...
- Developments in the production and quality control of poliovirus vaccines -- historical perspectivesJ Furesz
Bureau of Biologics, Health Canada, Ottawa, Ontario, Canada
Biologicals 34:87-90. 2006..By 1959 several candidate live oral poliovirus vaccines (OPV) had been developed...
- The risks, costs, and benefits of possible future global policies for managing poliovirusesKimberly M Thompson
Kids Risk Project, Harvard School of Public Health, 677 Huntington Ave, Third Floor, Boston, MA 02115, USA
Am J Public Health 98:1322-30. 2008..We assessed the costs, risks, and benefits of possible future major policy decisions on vaccination, surveillance, response plans, and containment following global eradication of wild polioviruses...
- A large vaccine-derived poliovirus outbreak on Madura Island--Indonesia, 2005Concepcion F Estivariz
Global Immunization Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 197:347-54. 2008..Suboptimal surveillance and a limited initial immunization response may have contributed to widespread circulation. Sensitive surveillance and prompt high-quality immunization responses are recommended to prevent the spread of VDPVs...
- Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40Eric A Engels
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
J Natl Cancer Inst 95:532-9. 2003Early poliovirus vaccines were accidentally contaminated with simian virus 40 (SV40). In Denmark, poliovirus vaccine was administered to most children from 1955 through 1961...
- The detection of Simian virus 40 in mesotheliomas from New Zealand and England using real time FRET probe PCR protocolsF Mayall
Department of Pathology, Waikato Hospital, Hamilton, New Zealand
J Clin Pathol 56:728-30. 2003..To detect Simian virus 40 (SV40) DNA in mesotheliomas from New Zealand and from England using novel real time FRET probe polymerase chain reaction (PCR) protocols...
- Costs and benefits of polio eradication: a long-run global perspectiveM Mahmud Khan
Tulane School of Public Health and Tropical Medicine, 1440 Canal Street, 1900, New Orleans, LA 70112, USA
Vaccine 21:702-5. 2003..In addition to the cost savings, the program will prevent 855000 deaths, 4 million paralysis cases and 40 million disability adjusted life years (DALYs) over the years 1970-2050...
- Vaccine innovation and adoption: polio vaccines in the UK, the Netherlands and West Germany, 1955-1965Ulrike Lindner
Clare Hall, Herschel Road, Cambridge CB3 9AL
Med Hist 50:425-46. 2006
- The role of routine polio immunization in the post-certification eraRoland W Sutter
Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland
Bull World Health Organ 82:31-9. 2004..This report reviews the key issues associated with each scenario, highlights the advantages and disadvantages of each scenario, and outlines the major challenges for policy decision-making...
- ELISA as a possible alternative to the neutralization test for evaluating the immune response to poliovirus vaccinesAlexander P Ivanov
United States Food and Drug Administration, Center for Biologics Evaluation and Research, 1401 Rockville Pike, Rockville, MD 20852, USA
Expert Rev Vaccines 4:167-72. 2005....
- The vaccine origin of the 1968 epidemic of type 3 poliomyelitis in PolandJ Martin
Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
Virology 278:42-9. 2000..These findings may provide essential insights into the strategies for stopping polio immunisation once wild poliovirus has been eradicated...
- Characterization of CHAT and Cox type 1 live-attenuated poliovirus vaccine strainsJavier Martin
Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom
J Virol 76:5339-49. 2002..The molecular mechanisms of attenuation and evolution of poliovirus in humans are discussed in the context of the global polio eradication initiative...
- Global public health mandates in a diverse world: the polio eradication initiative and the expanded programme on immunization in sub-Saharan Africa and South AsiaSekhar Bonu
Asian Development Bank, Manila, Philippines
Health Policy 70:327-45. 2004..We investigated whether today's EPIs are ensuring universal and equitable vaccine coverage; and whether the removal of extra inputs associated with the implementation of NIDs is likely to affect EPI coverage and equity...
- Vaccination against polio should not be stoppedKonstantin Chumakov
Konstantin Chumakov is at the Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, Maryland 20852, USA
Nat Rev Microbiol 5:952-8. 2007..It is crucially important that high levels of population immunity are maintained against polio in the foreseeable future...
- Trends in U.S. pleural mesothelioma incidence rates following simian virus 40 contamination of early poliovirus vaccinesHoward D Strickler
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Natl Cancer Inst 95:38-45. 2003b>Poliovirus vaccines that were used during the late 1950s and early 1960s were contaminated with simian virus 40 (SV40), a monkey virus that is tumorigenic in rodents...
- Presence of simian virus 40 (SV40) is not frequent in Swedish malignant mesotheliomasPeter Priftakis
Department of Oncology Pathology, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden
Anticancer Res 22:1357-60. 2002..In Sweden, from 1958, due to production in Javanese macaque kidney cells and SV40 testing from 1961, only polio vaccine claimed to be free of SV40 has been used. Hence, we aimed to screen Swedish MM patients for the presence of SV40...
- The vaccines for children program. Policies, satisfaction, and vaccine deliveryR K Zimmerman
Department of Family Medicine and Clinical Epidemiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Prev Med 21:243-9. 2001..Characterize the Vaccines for Children (VFC) programs in Minnesota and Pennsylvania, assess providers' satisfaction with each state's program, and examine changes in doses administered in the public sector since implementation of the VFC...
- Is there an association between SV40 contaminated polio vaccine and lymphoproliferative disorders? An age-period-cohort analysis on Norwegian data from 1953 to 1997Guri Olsen Thu
The Cancer Registry of Norway Institute of Population based Cancer Research, Montebello, Oslo, Norway
Int J Cancer 118:2035-9. 2006..Thus, our data do not support the hypothesis of an association between the vaccine and any subgroup of lymphoproliferative diseases...
- Recombinant vaccine-derived poliovirus in MadagascarDominique Rousset
Emerg Infect Dis 9:885-7. 2003
- Immune status to polioviruses in the child population of Romania between 2002-2005 as indicated by serological investigation in cases of acute flaccid paralysis (AFP) and facial paralysis (FP) and its use as a "national reference value" to evaluAnda Baicus
I Cantacuzino National Institute of Research Development for Microbiology and Immunology, Bucharest
Rev Med Chir Soc Med Nat Iasi 110:1004-11. 2006..The risk of the emergence and spread of cVDPVs remains present especially in "at risk" groups with the gaps in immunity, even in countries where indigenous wild polioviruses have already been eradicated...
- Polio fight falters as Yemen and Java report fresh casesCarina Dennis
Nature 435:133. 2005
- [Failure to eradicate polio]Tapani Hovi
WHO Collaborating Centre for Poliovirus Surveillance, Enterovirus Research, Kansanterveyslaitos, Helsinki
Duodecim 121:477-8. 2005
- A global call for new polio vaccinesDavid L Heymann
Global Polio Eradication Initiative, World Health Organization, 20 Avenue Appia, CH 1211 Geneva, Switzerland
Nature 434:699-700. 2005
- Some ethical issues arising from polio eradication programmes in IndiaYash Paul
A D 7, Devi Marg, Bani Park, Jaipur 302016, India
Bioethics 19:393-406. 2005..There is a real danger that if these issues are not addressed then public trust in the eradication programme and vaccination programmes as a whole will be lost...
- [Collective poliomyelitis immunity in the adult population and its impact on eradication of this infection]V B Seĭbil'
Vopr Virusol 52:44-7. 2007..It is concluded that it is impossible to eradicate poliomyelitis as infection today; it is possible only to eliminate the disease if further vaccination of children is performed with live poliomyelitis vaccine...
- Population immunity to polioviruses among preschool children from four urban underserved low income communities, United States, 1997-2001D Rebecca Prevots
National Immunization Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 23:1130-6. 2004..To evaluate the impact of the change in polio vaccination schedule on population immunity, we conducted a seroprevalence survey among low income preschool children from selected urban areas...
- Risks of reintroduction of polio after eradication: the vaccine origin of an outbreak of type 3 poliomyelitisJ Martin
Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, UK
Dev Biol (Basel) 105:83-92. 2001....
- A combined diphtheria, tetanus, five-component acellular pertussis, poliovirus and Haemophilus influenzae type b vaccineSteven Black
Kaiser Permanente Vaccine Study Center, 1 Kaiser Plaza, 16th Floor, Oakland, CA, USA
Expert Rev Vaccines 4:793-805. 2005..In published studies, the safety, immunogenicity and effectiveness of this combination vaccine were comparable with those of separately administered vaccines, with the advantage of a simplified dosing schedule...
- Poliomyelitis and the role of risk analysis in global infectious disease policy and managementKimberly M Thompson
Massachusetts Institute of Technology, Sloan School of Management, System Dynamics Group, Cambridge, MA 02142, USA
Risk Anal 26:1419-21. 2006
- Evaluation of response scenarios to potential polio outbreaks using mathematical modelsKimberly M Thompson
Massachusetts Institute of Technology, Sloan School of Management, Cambridge, MA 02142, USA
Risk Anal 26:1541-56. 2006..Finally, long after oral poliovirus vaccine cessation the choice of target age groups during a response represents an important consideration...
- Annual report of the Australian National Poliovirus Reference Laboratory 2005Kerri Anne Brussen
Victorian Infectious Diseases Reference Laboratory, Carlton South, Victoria
Commun Dis Intell Q Rep 30:334-40. 2006....
- Recommendations of 2nd National Consultative Meeting of Indian Academy of Pediatrics (IAP) on polio eradication and improvement of routine immunizationVipin M Vashishtha
Indian Pediatr 45:367-78. 2008....
- [The World Health Organization and the problem of elimination of infectious diseases in the world]V B Seĭbil'
Vopr Virusol 50:60-4. 2005
- Virus attenuation by genome-scale changes in codon pair biasJ Robert Coleman
Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA
Science 320:1784-7. 2008..Polioviruses thus customized were used to immunize mice and provided protective immunity after challenge. This "death by a thousand cuts" strategy could be generally applicable to attenuating many kinds of viruses...
- A polio-free world?Paul Webster
Lancet 366:359-60. 2005
- A dynamic model of poliomyelitis outbreaks: learning from the past to help inform the futureRadboud J Duintjer Tebbens
KidsRisk Project, Harvard School of Public Health, Boston, MA 02115, USA
Am J Epidemiol 162:358-72. 2005..The authors expect that this model can provide important insights into the dynamics of future potential poliomyelitis outbreaks and in this way serve as a useful tool for risk assessment...
- The eradication of polio--progress and challengesMark A Pallansch
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 355:2508-11. 2006
- Vaccination strategies for the last stages of global polio eradicationFrancois Bompart
Aventis Pasteur, 2 avenue Pont Pasteur, 69367 Lyon Cedex 07, France
Indian Pediatr 42:163-9. 2005..The main strategies under consideration are a surveillance and response approach or a continuation of vaccination with IPV. Choosing between these strategies will pose a major dilemma for India and for many other countries...
- Eradicating polioDavid L Heymann
Polio Eradication Initiative, World Health Organization, Geneva
N Engl J Med 351:1275-7. 2004
- Disease eradication. Two steps forward, one step back in polio fightLeslie Roberts
Science 304:1096. 2004
- Setback in polio eradication in India in 2002: reasons and remediesYash Paul
Indian Pediatr 41:202-3; author reply 203-4. 2004
- Global efforts to eradicate polioValerie F Krym
CMAJ 170:189-90. 2004
- Surveillance of poliomyelitis in Italy: immunity status of population against polio and environmental circulation of Poliovirus. General illustration of the resultsA M Patti
Department of Public Health Sciences, University La Sapienza of Rome
Ann Ig 14:1-57. 2002
- Survival of previously measles-vaccinated and measles-unvaccinated children in an emergency situation: an unplanned studyPeter Aaby
Bandim Health Project, Bissau, Guinea Bissau
Pediatr Infect Dis J 22:798-805. 2003..However, these observations have not been based on randomized trials...
- Immunity to poliomyelitis in VictoriansKatharine Hogg
Murdoch Children s Research Institute, Royal Children s Hospital, Department of Microbiology and Immunology, The University of Melbourne, Victoria
Aust N Z J Public Health 26:432-6. 2002....
- WHO prepares for final push to rid the world of polioDeclan Butler
Nature 424:604. 2003
- Vaccines should be kept even if polio is wiped outJeronimo Cello
Nature 418:915. 2002
- Hygiene in the home: relating bugs and behaviourVal Curtis
Department of Infectious and Tropical Diseases, DCVBU ITD London School of Hygiene and Tropical Medicine, Kepple Street, London WCIE 7HT, UK
Soc Sci Med 57:657-72. 2003..A better understanding of the household transmission of the agents of IID using multidisciplinary methods is needed if effective hygiene promotion programmes are to be designed...
- Tears often shedMargaret Burgess
National Centre for Immunisation Research, The University of Sydney and The Children s Hospital at Westmead
N S W Public Health Bull 14:5-8. 2003
- [History of poliomyelitis infection in the world and in Poland ]Wiesław Magdzik
Przegl Epidemiol 56:519-30. 2002..An impact of vaccination on epidemiological situation of poliomyelitis in the world and in Poland has been illustrated. The general principles and results of global poliomyelitis eradication program have been reported...
- Poliovirus cases rise in IndiaCathel Kerr
Lancet Infect Dis 3:264. 2003
- Polio eradication: finishing the job and protecting the investmentDavid L Heymann
Bull World Health Organ 82:1. 2004
- Polio eradication in Australia and the worldPaul Roche
Commun Dis Intell Q Rep 26:113-7. 2002
- Protection against vaccine-preventable diseases in medical studentsGurli Baer
Division of Pediatric Infectious Diseases, University Children s Hospital Basel, CH 4005 Basel, Switzerland
Pediatr Infect Dis J 22:373-4. 2003
- Declining trend in routine UIP coverageS DasGupta
Department of Community Medicine, NRS Medical College, Calcutta
Indian J Public Health 45:20-3. 2001..There is urgent need for further probing to identify the reasons for such poor state of affairs, keeping PPI angle in mind and to initiate remedial measure urgently...
- Polio extraimmunization in children younger than 2 years after changes in immunization recommendationsLoren K Mell
Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
Pediatrics 111:296-301. 2003..To investigate trends over time in polio extraimmunization among children in 4 large health maintenance organizations and to study the association with recent changes in polio immunization policy...
- Need for re-appraisal of acute flaccid paralysis (AFP) case classificationY Paul
Vaccine 22:3829-30. 2004
- Poliovirus vaccination during pregnancy, maternal seroconversion to simian virus 40, and risk of childhood cancerE A Engels
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Am J Epidemiol 160:306-16. 2004..The authors conclude that an increased cancer risk in CPP children whose mothers received pre-1963 poliovirus vaccine was unlikely to have been due to SV40 infection transmitted from mothers to their children...
- Nigerian state of Kano resumes polio vaccinationFiona Fleck
BMJ 329:70. 2004
- The problems of polio eradicationAlan W Dove
Science 304:1903. 2004
- [Characterization of poliovirus vaccine strains isolated in the country with high level of immunization coverage]E O Samoilovich
Vopr Virusol 47:27-32. 2002....
- Progress towards polio eradication: an African perspectiveB D Schoub
National Institute for Virology, Sandringham, South Africa
Dev Biol (Basel) 105:9-19. 2001..International political commitment and focussed and empowering developmental aid are urgently needed...
- [Global eradication of poliomyelitis in 2005: progress, priorities, problems]Claude Chastel
Bull Soc Pathol Exot 95:63-5. 2002
- Enterovirus RNA Translation and ReplicationDavid J Barton; Fiscal Year: 2013..This information can be used to improve poliovirus vaccines, to create new vaccines against related human picornaviruses, and to optimize antiviral drugs designed to ..
- Genetically stable Picornavirus HIV Immunization vectorMatthias Gromeier; Fiscal Year: 2004..Infection with live attenuated poliovirus vaccines is known to induce potent immune responses upon replication in the gastrointestinal tract of immunized ..
- MOLECULAR ANALYSIS OF POLIOVIRUS NEURTRALIZING EPITOPESMarie Chow; Fiscal Year: 1999The success of the poliovirus vaccines have strongly influenced current concepts about how vaccines work...
- Hamster Model for AIDS LymphomasJANET BUTEL; Fiscal Year: 2003..In addition, this project may provide new insights into lymphomagenesis in general and may lead to the development of new diagnostic and therapeutic approaches to this malignancy. ..
- SV40 Pathogenesis of Human InfectionsJANET BUTEL; Fiscal Year: 2008..This new information will allow better understanding of the biology of SV40 human infections and may provide insights into the mechanisms of SV40 involvement in human malignancies. [unreadable] [unreadable]..
- DETERMINING/UNDERSTANDING BARRIERS TO ADULT IMMUNIZATIONRichard Zimmerman; Fiscal Year: 2001..This project will furnish relevant, up-to-date to enhance policy planning, practice management and medical education. ..
- Insulin-like growth factor axis influence on HIV and HPV pathogenesis in womenHoward Strickler; Fiscal Year: 2008..abstract_text> ..
- Functions of 5' NCRs of picornavirus and cellular mRNAsBERT SEMLER; Fiscal Year: 2008..abstract_text> ..
- Enterovirus PathogenesisVINCENT RACANIELLO; Fiscal Year: 2007..The biological role of poliovirus-induced cleavage of RIG-I and MDA-5 will be determined. Because poliovirus is a model pathogen, the results will contribute to the control of other medically relevant viruses. ..
- HOST DEFENSE TO NEONATAL INRACELLULAR PATHOGENSChristopher Wilson; Fiscal Year: 2008..These studies will provide insights into mechanisms for host defense against Lm and for the greater susceptibility of the neonate to this and related intracellular bacterial pathogens. ..
- LSR II ANALYZERChristopher Wilson; Fiscal Year: 2005..This application documents the limitations of our current facility in meeting the needs of these investigators for access to contemporary flow cytometry instruments and how an LSR II analyzer would allow us to meet these needs. ..
- Dendritic Cell-Based Immunotherapy for HIV InfectionCharles Rinaldo; Fiscal Year: 2005..We believe that this novel immunotherapy strategy ideally fulfills the intent of the NIAID Integrated Preclinical/Clinical Program. ..
- Transgenic Mouse Model for Echovirus PathogenesisVINCENT RACANIELLO; Fiscal Year: 2004..Establishment of a small animal model may yield information about echovirus pathogenesis that could stimulate development of echovirus vaccines or antiviral drugs. ..
- DNA METHYLATION IN T CELL DEVELOPMENT AND FUNCTIONChristopher Wilson; Fiscal Year: 2004..2) The increased numbers of TCRgammabeta thymocytes will reflect either increased locus accessibility and rearrangement of the relevant gammabeta TCR genes or reduced Notch signaling. ..
- ANTI-HIV T CELL RESPONSES DURING ANTIVIRAL DRUG THERAPYCharles Rinaldo; Fiscal Year: 2003..We believe that these new, novel antigen delivery systems and processing methods will be highly efficient at inducing a broad spectrum of anti-HIV-1 T cell responses in ART patients. ..
- REGULATION OF PSEUDOMONAS INDUCED LUNG INFLAMMATIONChristopher Wilson; Fiscal Year: 2003..Hypothesis: CFTR KO mice will have excessive lung inflammation. This will reflect a process intrinsic to the lung and will parallel and be dependent, at least in part, on NF-kappaB activation in the airway epithelium. ..
- Insulin and IGF In female colon, breast, uterine cancerHoward Strickler; Fiscal Year: 2005....
- Effects of HLA and KIR genotype on HIV and HCVHoward Strickler; Fiscal Year: 2006..WlHS is a large, racially and geographically diverse cohort of HIV(+) (n=2761 with - 40% HCV(+)), and HIV(-) women who share similar risk factors (n=942 with - 25%HCV(+)). ..
- POLIOVIRUS USING INFECTIOUS VIRAL CDNA CLONEVINCENT RACANIELLO; Fiscal Year: 2002..The results of these experiments will contribute to the long term goal of this research, which is to provide a complete description of the replication and pathogenesis of a human viral pathogen. ..