poliovirus vaccines

Summary

Summary: Vaccines used to prevent POLIOMYELITIS. They include inactivated (POLIOVIRUS VACCINE, INACTIVATED) and oral vaccines (POLIOVIRUS VACCINE, ORAL).

Top Publications

  1. ncbi The pathogenesis of poliomyelitis: what we don't know
    Neal Nathanson
    Department of Microbiology and Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Virus Res 71:1-50. 2008
  2. pmc From emergence to eradication: the epidemiology of poliomyelitis deconstructed
    Neal Nathanson
    Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Am J Epidemiol 172:1213-29. 2010
  3. ncbi The 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) coadministered with DTPw-HBV/Hib and poliovirus vaccines: assessment of immunogenicity
    Nancy Bermal
    Research Institute for Tropical Medicine, Filinvest Corporate City, Alabang, Muntinlupa City, The Philippines
    Pediatr Infect Dis J 28:S89-96. 2009
  4. pmc Recombination between polioviruses and co-circulating Coxsackie A viruses: role in the emergence of pathogenic vaccine-derived polioviruses
    Sophie Jegouic
    Institut Pasteur, Unité de Biologie des virus entériques, Paris, France
    PLoS Pathog 5:e1000412. 2009
  5. ncbi An outbreak of poliomyelitis caused by type 1 vaccine-derived poliovirus in China
    Xiaofeng Liang
    National Immunization Programme, China Center for Disease Control and Prevention, Beijing, People s Republic of China, 100044
    J Infect Dis 194:545-51. 2006
  6. pmc Outbreak of type 2 vaccine-derived poliovirus in Nigeria: emergence and widespread circulation in an underimmunized population
    Steven Wassilak
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 203:898-909. 2011
  7. ncbi Protective efficacy of a monovalent oral type 1 poliovirus vaccine: a case-control study
    Nicholas C Grassly
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Lancet 369:1356-62. 2007
  8. ncbi Transmission of imported vaccine-derived poliovirus in an undervaccinated community in Minnesota
    James P Alexander
    National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 199:391-7. 2009
  9. ncbi [German Health survey 1997/98: immune status against poliomyelitis]
    S Diedrich
    Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch Institut, Berlin
    Dtsch Med Wochenschr 125:584-8. 2000
  10. ncbi Mucosal immunity and poliovirus vaccines: impact on wild poliovirus infection and transmission
    Hiromasa Okayasu
    Polio Eradication Initiative, World Health Organization, Geneva, Switzerland
    Vaccine 29:8205-14. 2011

Research Grants

  1. Enterovirus RNA Translation and Replication
    David J Barton; Fiscal Year: 2013
  2. Genetically stable Picornavirus HIV Immunization vector
    Matthias Gromeier; Fiscal Year: 2004
  3. MOLECULAR ANALYSIS OF POLIOVIRUS NEURTRALIZING EPITOPES
    Marie Chow; Fiscal Year: 1999
  4. Hamster Model for AIDS Lymphomas
    JANET BUTEL; Fiscal Year: 2003
  5. SV40 Pathogenesis of Human Infections
    JANET BUTEL; Fiscal Year: 2008
  6. DETERMINING/UNDERSTANDING BARRIERS TO ADULT IMMUNIZATION
    Richard Zimmerman; Fiscal Year: 2001
  7. Insulin-like growth factor axis influence on HIV and HPV pathogenesis in women
    Howard Strickler; Fiscal Year: 2008
  8. Functions of 5' NCRs of picornavirus and cellular mRNAs
    BERT SEMLER; Fiscal Year: 2008
  9. Enterovirus Pathogenesis
    VINCENT RACANIELLO; Fiscal Year: 2007
  10. HOST DEFENSE TO NEONATAL INRACELLULAR PATHOGENS
    Christopher Wilson; Fiscal Year: 2008

Detail Information

Publications172 found, 100 shown here

  1. ncbi The pathogenesis of poliomyelitis: what we don't know
    Neal Nathanson
    Department of Microbiology and Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Virus Res 71:1-50. 2008
    ..been eradicated while types 1 and 3 have not? (12) Can transmission of vaccine-derived polioviruses be prevented with inactivated poliovirus vaccine? (13) What is the best strategy to control and eliminate vaccine-derived polioviruses?..
  2. pmc From emergence to eradication: the epidemiology of poliomyelitis deconstructed
    Neal Nathanson
    Department of Microbiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Am J Epidemiol 172:1213-29. 2010
    ..Beginning in 1955, the creation of poliovirus vaccines led to a stepwise reduction in poliomyelitis, culminating in the unpredicted elimination of wild ..
  3. ncbi The 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) coadministered with DTPw-HBV/Hib and poliovirus vaccines: assessment of immunogenicity
    Nancy Bermal
    Research Institute for Tropical Medicine, Filinvest Corporate City, Alabang, Muntinlupa City, The Philippines
    Pediatr Infect Dis J 28:S89-96. 2009
    ....
  4. pmc Recombination between polioviruses and co-circulating Coxsackie A viruses: role in the emergence of pathogenic vaccine-derived polioviruses
    Sophie Jegouic
    Institut Pasteur, Unité de Biologie des virus entériques, Paris, France
    PLoS Pathog 5:e1000412. 2009
    ....
  5. ncbi An outbreak of poliomyelitis caused by type 1 vaccine-derived poliovirus in China
    Xiaofeng Liang
    National Immunization Programme, China Center for Disease Control and Prevention, Beijing, People s Republic of China, 100044
    J Infect Dis 194:545-51. 2006
    ..In May-July 2004, type 1 vaccine-derived poliovirus (VDPV) was isolated from 2 case patients with polio and a contact of a third case patient in Guizhou Province...
  6. pmc Outbreak of type 2 vaccine-derived poliovirus in Nigeria: emergence and widespread circulation in an underimmunized population
    Steven Wassilak
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 203:898-909. 2011
    ..Strengthened routine immunization programs in countries with suboptimal coverage and balanced use of OPV formulations in SIAs are necessary to minimize risks of VDPV emergence and circulation...
  7. ncbi Protective efficacy of a monovalent oral type 1 poliovirus vaccine: a case-control study
    Nicholas C Grassly
    Department of Infectious Disease Epidemiology, Imperial College London, London, UK
    Lancet 369:1356-62. 2007
    ..A high-potency monovalent oral type 1 poliovirus vaccine (mOPV1) was developed in 2005 to tackle persistent poliovirus transmission in the last remaining infected countries. Our aim was to assess the efficacy of this vaccine in India...
  8. ncbi Transmission of imported vaccine-derived poliovirus in an undervaccinated community in Minnesota
    James P Alexander
    National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 199:391-7. 2009
    ..An investigation was conducted to determine the source of the virus and its means of transmission...
  9. ncbi [German Health survey 1997/98: immune status against poliomyelitis]
    S Diedrich
    Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch Institut, Berlin
    Dtsch Med Wochenschr 125:584-8. 2000
    ..One of the goals of the WHO is the worldwide eradication of poliomyelitis in the next years. A high level of population immunity protects against imported wild viruses from endemic areas...
  10. ncbi Mucosal immunity and poliovirus vaccines: impact on wild poliovirus infection and transmission
    Hiromasa Okayasu
    Polio Eradication Initiative, World Health Organization, Geneva, Switzerland
    Vaccine 29:8205-14. 2011
    ....
  11. pmc Immunity status against poliomyelitis in Germany: determination of cut-off values in International Units
    Sabine Diedrich
    Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany
    BMC Infect Dis 2:2. 2002
    ..Standard methodology for determination of polio antibodies is a feature aimed at obtaining consistent results. An International Standard Serum for polio antibodies exists, but no protective level in International Units is defined...
  12. ncbi Seroprevalence of antibodies to poliovirus in individuals living in Portugal, 2002
    M Pires de Miranda
    Unidade de Vírus Respiratórios e Enterovirus, Instituto Nacional de Saude, Unit of Respiratory and Enteroviruses, National Health Institute, INS, Lisbon, Portugal
    Euro Surveill 12:E7-8. 2007
    ..For poliovirus type 3, the suboptimal antibody levels observed in teenagers and young adults suggest the need for a booster dose to minimise the risk of wild poliovirus importation...
  13. ncbi Primary vaccination of adults with reduced antigen-content diphtheria-tetanus-acellular pertussis or dTpa-inactivated poliovirus vaccines compared to diphtheria-tetanus-toxoid vaccines
    Heidi Theeten
    University of Antwerp, Universiteitsplein 1, Wilrijk, Belgium
    Curr Med Res Opin 23:2729-39. 2007
    ....
  14. ncbi Immunity to poliomyelitis in The Netherlands
    M A Conyn-van Spaendonck
    Department of Infectious Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Am J Epidemiol 153:207-14. 2001
    ....
  15. ncbi [Regional variations of adult population vaccinal status]
    J Beytout
    Service de Maladies Infectieuses, Hotel Dieu, Clermont Ferrand, France
    Med Mal Infect 34:460-8. 2004
    ..The authors had for aim to study the regional variations of vaccination coverage in adult population...
  16. ncbi Poliovirus detection in wastewater and stools following an immunization campaign in Havana, Cuba
    Pedro Mas Lago
    Instituto de Medicina Tropical Pedro Kouri, Autopista Novia del Mediodia, Km 6, entre Autopista Nacional y Carretera Central, La Lisa, Havana City, Cuba
    Int J Epidemiol 32:772-7. 2003
    ..In this study, we evaluated the sensitivity of wastewater sampling by concurrently collecting stools from children aged < 3 years attending two neighbourhood clinics in Havana, Cuba, and wastewater from the same neighbourhoods...
  17. ncbi Poliovirus circulation among schoolchildren during the early phase of the 1992-1993 poliomyelitis outbreak in The Netherlands
    P M Oostvogel
    National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    J Infect Dis 184:1451-5. 2001
    ..No evidence of vaccination was seen in 25.5%-43.1% of children at OR schools. Seroprevalence of antibodies against the 3 types of poliovirus suggested that no poliovirus circulation had occurred between the 1978 and 1992-1993 outbreaks...
  18. ncbi Polio eradication initiative in India: deconstructing the GPEI
    C Sathyamala
    Centre of Social Medicine and Community Health, Jawaharlal Nehru University, New Delhi, India
    Int J Health Serv 35:361-83. 2005
    ..They conclude that the GPEI is yet another exercise in mismanaging the health priorities and programs in developing countries in the era of globalization...
  19. pmc Rational design of genetically stable, live-attenuated poliovirus vaccines of all three serotypes: relevance to poliomyelitis eradication
    Andrew J Macadam
    NIBSC, South Mimms, Herts, UK
    J Virol 80:8653-63. 2006
    ....
  20. ncbi Low incidence of SV40-like sequences in ependymal tumours
    F J Reuther
    Department of Pathology, University Hospitals of Ulm, Ulm, Germany
    J Pathol 195:580-5. 2001
    Between 1955 and 1963, millions of children and adults were exposed to SV40-contaminated poliovirus vaccines. The oncogenic potential of this polyomavirus was revealed when intracerebral inoculation of SV40 into newborn hamsters resulted ..
  21. ncbi Highly divergent neurovirulent vaccine-derived polioviruses of all three serotypes are recurrently detected in Finnish sewage
    M Roivainen
    National Institute for Health and Welfare, Helsinki, Finland
    Euro Surveill 15:pii/19566. 2010
    ..While the source of the VDPV is unknown, characteristics of the viruses resemble those of strains isolated from immunodeficient, persistently infected persons. No cases of suspected poliomyelitis have been reported in Finland since 1985...
  22. ncbi Polio eradication in India: some observations
    Yash Paul
    A D 7, Devi Marg, Bani Park, Jaipur 202016, India
    Vaccine 22:4144-8. 2004
    ..Vaccine failure has exaggerated the problem of VAPP. No efforts have been made to find the causes for high incidence of vaccine failure and VAPP...
  23. ncbi Surge in polio spreads alarm in northern Nigeria. Rumours about vaccine safety in Muslim-run states threaten WHO's eradication programme
    Clare Kapp
    Lancet 362:1631-2. 2003
  24. ncbi Characterization of a rare natural intertypic type 2/type 3 penta-recombinant vaccine-derived poliovirus isolated from a child with acute flaccid paralysis
    Yong Zhang
    WHO WPRO Regional Polio Reference Laboratory and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No 27 Nanwei Road, Xuanwu District, Beijing 100050, PR China
    J Gen Virol 91:421-9. 2010
    ..This is the first report on the isolation of a type 2/type 3 poliovirus capsid recombinant with one of the five crossover sites located in the VP1 coding region...
  25. ncbi A case for developing antiviral drugs against polio
    Marc S Collett
    ViroDefense Inc, 155 Gibbs Street, Suite 529, Rockville, MD 20850, United States
    Antiviral Res 79:179-87. 2008
    ..Given the timelines for eradication and those for drug development, the time for action is now...
  26. ncbi Recurrent isolation of poliovirus 3 strains with chimeric capsid protein Vp1 suggests a recombination hot-spot site in Vp1
    Soile Blomqvist
    National Institute for Health and Welfare THL, Department of Infectious Disease Surveillance and Control, Intestinal Viruses Unit, P O Box 30, 00271 Helsinki, Finland
    Virus Res 151:246-51. 2010
    ..Our results suggest that there exists a PV3/PV2 recombination hot-spot site in the 3' partial region of the VP1 capsid protein and that the recombination may occur within weeks or a few months after the administration of OPV...
  27. pmc Future of polio vaccines
    Ellie Ehrenfeld
    National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA
    Expert Rev Vaccines 8:899-905. 2009
    ..Shifting factors in the risk-benefit-cost equation favor the creation of new poliovirus vaccines for use in the foreseeable future...
  28. ncbi Lack of serologic evidence for prevalent simian virus 40 infection in humans
    Joseph J Carter
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 95:1522-30. 2003
    Propagation of poliovirus in monkey kidney cells led to the inadvertent contamination of poliovirus vaccines with simian virus 40 (SV40) between 1955 and 1963...
  29. ncbi Successful co-administration of a human rotavirus and oral poliovirus vaccines in Bangladeshi infants in a 2-dose schedule at 12 and 16 weeks of age
    K Zaman
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, GPO Box 128, Mohakhali, Dhaka 1000, Bangladesh
    Vaccine 27:1333-9. 2009
    ..No statistically significant differences were observed between groups for polio seroprotection rates. RIX4414 vaccine was immunogenic when co-administered with OPV and did not interfere with OPV seroprotection rates...
  30. pmc Multiplex PCR method for identifying recombinant vaccine-related polioviruses
    David R Kilpatrick
    Respiratory and Enteric Virus Branch, G 10, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 42:4313-5. 2004
    ..Six pairs of Sabin strain-specific recombinant primers were designed to permit rapid screening for VDPV recombinants by PCR...
  31. ncbi One hundred years of poliovirus pathogenesis
    Vincent R Racaniello
    Department of Microbiology, Columbia University College of Physicians and Surgeons, 701 W 168th St, New York, NY 10032, USA
    Virology 344:9-16. 2006
    ..Nearly 50 years later, when two effective poliovirus vaccines were developed, the impetus to study poliovirus pathogenesis waned...
  32. ncbi Poliovirus vaccine strains detected in stool specimens of immunodeficient children in South Africa
    Dobromir N Pavlov
    Department of Medical Virology, University of Pretoria NHLS, PO Box 2034, Pretoria 0001, South Africa
    Diagn Microbiol Infect Dis 54:23-30. 2006
    ..Therefore, the information obtained in this study would be essential for strategies aimed at the protection of both immunodeficient as well as immunocompetent individuals against complications of vaccination with OPV...
  33. ncbi Isolation and characterization of circulating type 1 vaccine-derived poliovirus from sewage and stream waters in Hispaniola
    Jan Vinje
    Department of Environmental Sciences and Engineering, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7431, USA
    J Infect Dis 189:1168-75. 2004
    ..Our findings demonstrate a useful role for environmental surveillance of neurovirulent polioviruses in the overall polio eradication program...
  34. ncbi Poliovirus vaccine shedding among persons with HIV in Abidjan, Cote d'Ivoire
    Karen A Hennessey
    Global Immunization Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30309, USA
    J Infect Dis 192:2124-8. 2005
    ..The present study was conducted to assess whether persons infected with human immunodeficiency virus (HIV) experience prolonged VDPV shedding and serve as a source of reintroduction of virus into the population...
  35. ncbi Eradication versus control for poliomyelitis: an economic analysis
    Kimberly M Thompson
    Kids Risk Project, Harvard School of Public Health, Boston, MA 02115, USA
    Lancet 369:1363-71. 2007
    ..Challenges in the four endemic areas combined with continuing demands for financial resources for eradication have led some to question the goal of eradication and to suggest switching to a policy of control...
  36. pmc Estimating the extent of vaccine-derived poliovirus infection
    Alison Wringe
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England
    PLoS ONE 3:e3433. 2008
    ....
  37. ncbi Polio today: are we on the verge of global eradication?
    Stephen L Cochi
    Centers for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Rd NE, Mailstop E 05, Atlanta, GA 30333, USA
    JAMA 300:839-41. 2008
  38. ncbi [The German Health Interview and Examination Survey for Children and Adolescents (KiGGS): state of immunity against poliomyelitis in German children]
    S Diedrich
    Robert Koch Institut, Berlin, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 50:771-4. 2007
    ..The seroprevalence of antibodies against all three types of polioviruses indicates a very high level of population immunity in German children. It must be maintained through consequently performed vaccination programmes...
  39. ncbi Reemergence of recombinant vaccine-derived poliovirus outbreak in Madagascar
    Mala Rakoto-Andrianarivelo
    Unité de virologie, Institut Pasteur de Madagascar, Madagascar
    J Infect Dis 197:1427-35. 2008
    ..After the 2001-2002 poliomyelitis outbreak due to recombinant vaccine-derived polioviruses (VDPVs) in the Toliara province of Madagascar, another outbreak reoccurred in the same province in 2005...
  40. ncbi Developments in the production and quality control of poliovirus vaccines -- historical perspectives
    J Furesz
    Bureau of Biologics, Health Canada, Ottawa, Ontario, Canada
    Biologicals 34:87-90. 2006
    ..By 1959 several candidate live oral poliovirus vaccines (OPV) had been developed...
  41. pmc The risks, costs, and benefits of possible future global policies for managing polioviruses
    Kimberly M Thompson
    Kids Risk Project, Harvard School of Public Health, 677 Huntington Ave, Third Floor, Boston, MA 02115, USA
    Am J Public Health 98:1322-30. 2008
    ..We assessed the costs, risks, and benefits of possible future major policy decisions on vaccination, surveillance, response plans, and containment following global eradication of wild polioviruses...
  42. ncbi A large vaccine-derived poliovirus outbreak on Madura Island--Indonesia, 2005
    Concepcion F Estivariz
    Global Immunization Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 197:347-54. 2008
    ..Suboptimal surveillance and a limited initial immunization response may have contributed to widespread circulation. Sensitive surveillance and prompt high-quality immunization responses are recommended to prevent the spread of VDPVs...
  43. ncbi Cancer incidence in Denmark following exposure to poliovirus vaccine contaminated with simian virus 40
    Eric A Engels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    J Natl Cancer Inst 95:532-9. 2003
    Early poliovirus vaccines were accidentally contaminated with simian virus 40 (SV40). In Denmark, poliovirus vaccine was administered to most children from 1955 through 1961...
  44. pmc The detection of Simian virus 40 in mesotheliomas from New Zealand and England using real time FRET probe PCR protocols
    F Mayall
    Department of Pathology, Waikato Hospital, Hamilton, New Zealand
    J Clin Pathol 56:728-30. 2003
    ..To detect Simian virus 40 (SV40) DNA in mesotheliomas from New Zealand and from England using novel real time FRET probe polymerase chain reaction (PCR) protocols...
  45. ncbi Costs and benefits of polio eradication: a long-run global perspective
    M Mahmud Khan
    Tulane School of Public Health and Tropical Medicine, 1440 Canal Street, 1900, New Orleans, LA 70112, USA
    Vaccine 21:702-5. 2003
    ..In addition to the cost savings, the program will prevent 855000 deaths, 4 million paralysis cases and 40 million disability adjusted life years (DALYs) over the years 1970-2050...
  46. pmc Vaccine innovation and adoption: polio vaccines in the UK, the Netherlands and West Germany, 1955-1965
    Ulrike Lindner
    Clare Hall, Herschel Road, Cambridge CB3 9AL
    Med Hist 50:425-46. 2006
  47. pmc The role of routine polio immunization in the post-certification era
    Roland W Sutter
    Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 82:31-9. 2004
    ..This report reviews the key issues associated with each scenario, highlights the advantages and disadvantages of each scenario, and outlines the major challenges for policy decision-making...
  48. ncbi ELISA as a possible alternative to the neutralization test for evaluating the immune response to poliovirus vaccines
    Alexander P Ivanov
    United States Food and Drug Administration, Center for Biologics Evaluation and Research, 1401 Rockville Pike, Rockville, MD 20852, USA
    Expert Rev Vaccines 4:167-72. 2005
    ....
  49. ncbi The vaccine origin of the 1968 epidemic of type 3 poliomyelitis in Poland
    J Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
    Virology 278:42-9. 2000
    ..These findings may provide essential insights into the strategies for stopping polio immunisation once wild poliovirus has been eradicated...
  50. pmc Characterization of CHAT and Cox type 1 live-attenuated poliovirus vaccine strains
    Javier Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, United Kingdom
    J Virol 76:5339-49. 2002
    ..The molecular mechanisms of attenuation and evolution of poliovirus in humans are discussed in the context of the global polio eradication initiative...
  51. ncbi Global public health mandates in a diverse world: the polio eradication initiative and the expanded programme on immunization in sub-Saharan Africa and South Asia
    Sekhar Bonu
    Asian Development Bank, Manila, Philippines
    Health Policy 70:327-45. 2004
    ..We investigated whether today's EPIs are ensuring universal and equitable vaccine coverage; and whether the removal of extra inputs associated with the implementation of NIDs is likely to affect EPI coverage and equity...
  52. ncbi Vaccination against polio should not be stopped
    Konstantin Chumakov
    Konstantin Chumakov is at the Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, Maryland 20852, USA
    Nat Rev Microbiol 5:952-8. 2007
    ..It is crucially important that high levels of population immunity are maintained against polio in the foreseeable future...
  53. ncbi Trends in U.S. pleural mesothelioma incidence rates following simian virus 40 contamination of early poliovirus vaccines
    Howard D Strickler
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Natl Cancer Inst 95:38-45. 2003
    b>Poliovirus vaccines that were used during the late 1950s and early 1960s were contaminated with simian virus 40 (SV40), a monkey virus that is tumorigenic in rodents...
  54. ncbi Presence of simian virus 40 (SV40) is not frequent in Swedish malignant mesotheliomas
    Peter Priftakis
    Department of Oncology Pathology, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden
    Anticancer Res 22:1357-60. 2002
    ..In Sweden, from 1958, due to production in Javanese macaque kidney cells and SV40 testing from 1961, only polio vaccine claimed to be free of SV40 has been used. Hence, we aimed to screen Swedish MM patients for the presence of SV40...
  55. ncbi The vaccines for children program. Policies, satisfaction, and vaccine delivery
    R K Zimmerman
    Department of Family Medicine and Clinical Epidemiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Prev Med 21:243-9. 2001
    ..Characterize the Vaccines for Children (VFC) programs in Minnesota and Pennsylvania, assess providers' satisfaction with each state's program, and examine changes in doses administered in the public sector since implementation of the VFC...
  56. ncbi Is there an association between SV40 contaminated polio vaccine and lymphoproliferative disorders? An age-period-cohort analysis on Norwegian data from 1953 to 1997
    Guri Olsen Thu
    The Cancer Registry of Norway Institute of Population based Cancer Research, Montebello, Oslo, Norway
    Int J Cancer 118:2035-9. 2006
    ..Thus, our data do not support the hypothesis of an association between the vaccine and any subgroup of lymphoproliferative diseases...
  57. pmc Recombinant vaccine-derived poliovirus in Madagascar
    Dominique Rousset
    Emerg Infect Dis 9:885-7. 2003
  58. ncbi Immune status to polioviruses in the child population of Romania between 2002-2005 as indicated by serological investigation in cases of acute flaccid paralysis (AFP) and facial paralysis (FP) and its use as a "national reference value" to evalu
    Anda Baicus
    I Cantacuzino National Institute of Research Development for Microbiology and Immunology, Bucharest
    Rev Med Chir Soc Med Nat Iasi 110:1004-11. 2006
    ..The risk of the emergence and spread of cVDPVs remains present especially in "at risk" groups with the gaps in immunity, even in countries where indigenous wild polioviruses have already been eradicated...
  59. ncbi Polio fight falters as Yemen and Java report fresh cases
    Carina Dennis
    Nature 435:133. 2005
  60. ncbi [Failure to eradicate polio]
    Tapani Hovi
    WHO Collaborating Centre for Poliovirus Surveillance, Enterovirus Research, Kansanterveyslaitos, Helsinki
    Duodecim 121:477-8. 2005
  61. ncbi A global call for new polio vaccines
    David L Heymann
    Global Polio Eradication Initiative, World Health Organization, 20 Avenue Appia, CH 1211 Geneva, Switzerland
    Nature 434:699-700. 2005
  62. ncbi Some ethical issues arising from polio eradication programmes in India
    Yash Paul
    A D 7, Devi Marg, Bani Park, Jaipur 302016, India
    Bioethics 19:393-406. 2005
    ..There is a real danger that if these issues are not addressed then public trust in the eradication programme and vaccination programmes as a whole will be lost...
  63. ncbi [Collective poliomyelitis immunity in the adult population and its impact on eradication of this infection]
    V B Seĭbil'
    Vopr Virusol 52:44-7. 2007
    ..It is concluded that it is impossible to eradicate poliomyelitis as infection today; it is possible only to eliminate the disease if further vaccination of children is performed with live poliomyelitis vaccine...
  64. ncbi Population immunity to polioviruses among preschool children from four urban underserved low income communities, United States, 1997-2001
    D Rebecca Prevots
    National Immunization Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Pediatr Infect Dis J 23:1130-6. 2004
    ..To evaluate the impact of the change in polio vaccination schedule on population immunity, we conducted a seroprevalence survey among low income preschool children from selected urban areas...
  65. ncbi Risks of reintroduction of polio after eradication: the vaccine origin of an outbreak of type 3 poliomyelitis
    J Martin
    Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, UK
    Dev Biol (Basel) 105:83-92. 2001
    ....
  66. ncbi A combined diphtheria, tetanus, five-component acellular pertussis, poliovirus and Haemophilus influenzae type b vaccine
    Steven Black
    Kaiser Permanente Vaccine Study Center, 1 Kaiser Plaza, 16th Floor, Oakland, CA, USA
    Expert Rev Vaccines 4:793-805. 2005
    ..In published studies, the safety, immunogenicity and effectiveness of this combination vaccine were comparable with those of separately administered vaccines, with the advantage of a simplified dosing schedule...
  67. ncbi Poliomyelitis and the role of risk analysis in global infectious disease policy and management
    Kimberly M Thompson
    Massachusetts Institute of Technology, Sloan School of Management, System Dynamics Group, Cambridge, MA 02142, USA
    Risk Anal 26:1419-21. 2006
  68. ncbi Evaluation of response scenarios to potential polio outbreaks using mathematical models
    Kimberly M Thompson
    Massachusetts Institute of Technology, Sloan School of Management, Cambridge, MA 02142, USA
    Risk Anal 26:1541-56. 2006
    ..Finally, long after oral poliovirus vaccine cessation the choice of target age groups during a response represents an important consideration...
  69. ncbi Annual report of the Australian National Poliovirus Reference Laboratory 2005
    Kerri Anne Brussen
    Victorian Infectious Diseases Reference Laboratory, Carlton South, Victoria
    Commun Dis Intell Q Rep 30:334-40. 2006
    ....
  70. ncbi Recommendations of 2nd National Consultative Meeting of Indian Academy of Pediatrics (IAP) on polio eradication and improvement of routine immunization
    Vipin M Vashishtha
    Indian Pediatr 45:367-78. 2008
    ....
  71. ncbi [The World Health Organization and the problem of elimination of infectious diseases in the world]
    V B Seĭbil'
    Vopr Virusol 50:60-4. 2005
  72. pmc Virus attenuation by genome-scale changes in codon pair bias
    J Robert Coleman
    Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA
    Science 320:1784-7. 2008
    ..Polioviruses thus customized were used to immunize mice and provided protective immunity after challenge. This "death by a thousand cuts" strategy could be generally applicable to attenuating many kinds of viruses...
  73. ncbi A polio-free world?
    Paul Webster
    Lancet 366:359-60. 2005
  74. ncbi A dynamic model of poliomyelitis outbreaks: learning from the past to help inform the future
    Radboud J Duintjer Tebbens
    KidsRisk Project, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 162:358-72. 2005
    ..The authors expect that this model can provide important insights into the dynamics of future potential poliomyelitis outbreaks and in this way serve as a useful tool for risk assessment...
  75. ncbi The eradication of polio--progress and challenges
    Mark A Pallansch
    National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 355:2508-11. 2006
  76. ncbi Vaccination strategies for the last stages of global polio eradication
    Francois Bompart
    Aventis Pasteur, 2 avenue Pont Pasteur, 69367 Lyon Cedex 07, France
    Indian Pediatr 42:163-9. 2005
    ..The main strategies under consideration are a surveillance and response approach or a continuation of vaccination with IPV. Choosing between these strategies will pose a major dilemma for India and for many other countries...
  77. ncbi Eradicating polio
    David L Heymann
    Polio Eradication Initiative, World Health Organization, Geneva
    N Engl J Med 351:1275-7. 2004
  78. ncbi Disease eradication. Two steps forward, one step back in polio fight
    Leslie Roberts
    Science 304:1096. 2004
  79. ncbi Setback in polio eradication in India in 2002: reasons and remedies
    Yash Paul
    Indian Pediatr 41:202-3; author reply 203-4. 2004
  80. pmc Global efforts to eradicate polio
    Valerie F Krym
    CMAJ 170:189-90. 2004
  81. ncbi Surveillance of poliomyelitis in Italy: immunity status of population against polio and environmental circulation of Poliovirus. General illustration of the results
    A M Patti
    Department of Public Health Sciences, University La Sapienza of Rome
    Ann Ig 14:1-57. 2002
  82. ncbi Survival of previously measles-vaccinated and measles-unvaccinated children in an emergency situation: an unplanned study
    Peter Aaby
    Bandim Health Project, Bissau, Guinea Bissau
    Pediatr Infect Dis J 22:798-805. 2003
    ..However, these observations have not been based on randomized trials...
  83. ncbi Immunity to poliomyelitis in Victorians
    Katharine Hogg
    Murdoch Children s Research Institute, Royal Children s Hospital, Department of Microbiology and Immunology, The University of Melbourne, Victoria
    Aust N Z J Public Health 26:432-6. 2002
    ....
  84. ncbi WHO prepares for final push to rid the world of polio
    Declan Butler
    Nature 424:604. 2003
  85. ncbi Vaccines should be kept even if polio is wiped out
    Jeronimo Cello
    Nature 418:915. 2002
  86. ncbi Hygiene in the home: relating bugs and behaviour
    Val Curtis
    Department of Infectious and Tropical Diseases, DCVBU ITD London School of Hygiene and Tropical Medicine, Kepple Street, London WCIE 7HT, UK
    Soc Sci Med 57:657-72. 2003
    ..A better understanding of the household transmission of the agents of IID using multidisciplinary methods is needed if effective hygiene promotion programmes are to be designed...
  87. ncbi Tears often shed
    Margaret Burgess
    National Centre for Immunisation Research, The University of Sydney and The Children s Hospital at Westmead
    N S W Public Health Bull 14:5-8. 2003
  88. ncbi [History of poliomyelitis infection in the world and in Poland ]
    Wiesław Magdzik
    Przegl Epidemiol 56:519-30. 2002
    ..An impact of vaccination on epidemiological situation of poliomyelitis in the world and in Poland has been illustrated. The general principles and results of global poliomyelitis eradication program have been reported...
  89. ncbi Poliovirus cases rise in India
    Cathel Kerr
    Lancet Infect Dis 3:264. 2003
  90. pmc Polio eradication: finishing the job and protecting the investment
    David L Heymann
    Bull World Health Organ 82:1. 2004
  91. ncbi Polio eradication in Australia and the world
    Paul Roche
    Commun Dis Intell Q Rep 26:113-7. 2002
  92. ncbi Protection against vaccine-preventable diseases in medical students
    Gurli Baer
    Division of Pediatric Infectious Diseases, University Children s Hospital Basel, CH 4005 Basel, Switzerland
    Pediatr Infect Dis J 22:373-4. 2003
  93. ncbi Declining trend in routine UIP coverage
    S DasGupta
    Department of Community Medicine, NRS Medical College, Calcutta
    Indian J Public Health 45:20-3. 2001
    ..There is urgent need for further probing to identify the reasons for such poor state of affairs, keeping PPI angle in mind and to initiate remedial measure urgently...
  94. ncbi Polio extraimmunization in children younger than 2 years after changes in immunization recommendations
    Loren K Mell
    Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
    Pediatrics 111:296-301. 2003
    ..To investigate trends over time in polio extraimmunization among children in 4 large health maintenance organizations and to study the association with recent changes in polio immunization policy...
  95. ncbi Need for re-appraisal of acute flaccid paralysis (AFP) case classification
    Y Paul
    Vaccine 22:3829-30. 2004
  96. ncbi Poliovirus vaccination during pregnancy, maternal seroconversion to simian virus 40, and risk of childhood cancer
    E A Engels
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 160:306-16. 2004
    ..The authors conclude that an increased cancer risk in CPP children whose mothers received pre-1963 poliovirus vaccine was unlikely to have been due to SV40 infection transmitted from mothers to their children...
  97. pmc Nigerian state of Kano resumes polio vaccination
    Fiona Fleck
    BMJ 329:70. 2004
  98. ncbi The problems of polio eradication
    Alan W Dove
    Science 304:1903. 2004
  99. ncbi [Characterization of poliovirus vaccine strains isolated in the country with high level of immunization coverage]
    E O Samoilovich
    Vopr Virusol 47:27-32. 2002
    ....
  100. ncbi Progress towards polio eradication: an African perspective
    B D Schoub
    National Institute for Virology, Sandringham, South Africa
    Dev Biol (Basel) 105:9-19. 2001
    ..International political commitment and focussed and empowering developmental aid are urgently needed...
  101. ncbi [Global eradication of poliomyelitis in 2005: progress, priorities, problems]
    Claude Chastel
    Bull Soc Pathol Exot 95:63-5. 2002

Research Grants20

  1. Enterovirus RNA Translation and Replication
    David J Barton; Fiscal Year: 2013
    ..This information can be used to improve poliovirus vaccines, to create new vaccines against related human picornaviruses, and to optimize antiviral drugs designed to ..
  2. Genetically stable Picornavirus HIV Immunization vector
    Matthias Gromeier; Fiscal Year: 2004
    ..Infection with live attenuated poliovirus vaccines is known to induce potent immune responses upon replication in the gastrointestinal tract of immunized ..
  3. MOLECULAR ANALYSIS OF POLIOVIRUS NEURTRALIZING EPITOPES
    Marie Chow; Fiscal Year: 1999
    The success of the poliovirus vaccines have strongly influenced current concepts about how vaccines work...
  4. Hamster Model for AIDS Lymphomas
    JANET BUTEL; Fiscal Year: 2003
    ..In addition, this project may provide new insights into lymphomagenesis in general and may lead to the development of new diagnostic and therapeutic approaches to this malignancy. ..
  5. SV40 Pathogenesis of Human Infections
    JANET BUTEL; Fiscal Year: 2008
    ..This new information will allow better understanding of the biology of SV40 human infections and may provide insights into the mechanisms of SV40 involvement in human malignancies. [unreadable] [unreadable]..
  6. DETERMINING/UNDERSTANDING BARRIERS TO ADULT IMMUNIZATION
    Richard Zimmerman; Fiscal Year: 2001
    ..This project will furnish relevant, up-to-date to enhance policy planning, practice management and medical education. ..
  7. Insulin-like growth factor axis influence on HIV and HPV pathogenesis in women
    Howard Strickler; Fiscal Year: 2008
    ..abstract_text> ..
  8. Functions of 5' NCRs of picornavirus and cellular mRNAs
    BERT SEMLER; Fiscal Year: 2008
    ..abstract_text> ..
  9. Enterovirus Pathogenesis
    VINCENT RACANIELLO; Fiscal Year: 2007
    ..The biological role of poliovirus-induced cleavage of RIG-I and MDA-5 will be determined. Because poliovirus is a model pathogen, the results will contribute to the control of other medically relevant viruses. ..
  10. HOST DEFENSE TO NEONATAL INRACELLULAR PATHOGENS
    Christopher Wilson; Fiscal Year: 2008
    ..These studies will provide insights into mechanisms for host defense against Lm and for the greater susceptibility of the neonate to this and related intracellular bacterial pathogens. ..
  11. LSR II ANALYZER
    Christopher Wilson; Fiscal Year: 2005
    ..This application documents the limitations of our current facility in meeting the needs of these investigators for access to contemporary flow cytometry instruments and how an LSR II analyzer would allow us to meet these needs. ..
  12. Dendritic Cell-Based Immunotherapy for HIV Infection
    Charles Rinaldo; Fiscal Year: 2005
    ..We believe that this novel immunotherapy strategy ideally fulfills the intent of the NIAID Integrated Preclinical/Clinical Program. ..
  13. Transgenic Mouse Model for Echovirus Pathogenesis
    VINCENT RACANIELLO; Fiscal Year: 2004
    ..Establishment of a small animal model may yield information about echovirus pathogenesis that could stimulate development of echovirus vaccines or antiviral drugs. ..
  14. DNA METHYLATION IN T CELL DEVELOPMENT AND FUNCTION
    Christopher Wilson; Fiscal Year: 2004
    ..2) The increased numbers of TCRgammabeta thymocytes will reflect either increased locus accessibility and rearrangement of the relevant gammabeta TCR genes or reduced Notch signaling. ..
  15. ANTI-HIV T CELL RESPONSES DURING ANTIVIRAL DRUG THERAPY
    Charles Rinaldo; Fiscal Year: 2003
    ..We believe that these new, novel antigen delivery systems and processing methods will be highly efficient at inducing a broad spectrum of anti-HIV-1 T cell responses in ART patients. ..
  16. REGULATION OF PSEUDOMONAS INDUCED LUNG INFLAMMATION
    Christopher Wilson; Fiscal Year: 2003
    ..Hypothesis: CFTR KO mice will have excessive lung inflammation. This will reflect a process intrinsic to the lung and will parallel and be dependent, at least in part, on NF-kappaB activation in the airway epithelium. ..
  17. Insulin and IGF In female colon, breast, uterine cancer
    Howard Strickler; Fiscal Year: 2005
    ....
  18. Effects of HLA and KIR genotype on HIV and HCV
    Howard Strickler; Fiscal Year: 2006
    ..WlHS is a large, racially and geographically diverse cohort of HIV(+) (n=2761 with - 40% HCV(+)), and HIV(-) women who share similar risk factors (n=942 with - 25%HCV(+)). ..
  19. POLIOVIRUS USING INFECTIOUS VIRAL CDNA CLONE
    VINCENT RACANIELLO; Fiscal Year: 2002
    ..The results of these experiments will contribute to the long term goal of this research, which is to provide a complete description of the replication and pathogenesis of a human viral pathogen. ..