hazardous substances

Summary

Summary: Substances which, upon release into the atmosphere, water, or soil, or which, in direct contact with the skin, eyes, or mucous membranes, or as additives to food, cause health risks to humans or animals through absorption, inhalation, or ingestion. The concept includes safe handling, transportation, and storage of these substances.

Top Publications

  1. pmc Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical-gene-disease networks
    Allan Peter Davis
    Department of Bioinformatics, The Mount Desert Island Biological Laboratory, Salisbury Cove, ME 04672, USA
    Nucleic Acids Res 37:D786-92. 2009
  2. ncbi Genetic susceptibility to environmental toxicants in ALS
    Julia M Morahan
    The Stacey MND Laboratory, Department of Pathology, The University of Sydney, Sydney, New South Wales 2006, Australia
    Am J Med Genet B Neuropsychiatr Genet 144:885-90. 2007
  3. ncbi Amyotrophic lateral sclerosis and exposure to environmental toxins: an Australian case-control study
    Julia M Morahan
    Department of Pathology, University of Sydney, Sydney, Australia
    Neuroepidemiology 27:130-5. 2006
  4. pmc Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community
    Devon C Payne-Sturges
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Environ Health Perspect 112:589-98. 2004
  5. pmc Key scientific issues in the health risk assessment of trichloroethylene
    Weihsueh A Chiu
    National Center for Environmental Assessment, Office of Research and Development, U S Environmental Protection Agency, Washington, DC, USA
    Environ Health Perspect 114:1445-9. 2006
  6. ncbi The exposure data landscape for manufactured chemicals
    Peter P Egeghy
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, United States
    Sci Total Environ 414:159-66. 2012
  7. pmc Cigarettes sold in China: design, emissions and metals
    RICHARD J O'CONNOR
    Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Tob Control 19:i47-53. 2010
  8. ncbi Advancing exposure characterization for chemical evaluation and risk assessment
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health B Crit Rev 13:299-313. 2010
  9. ncbi European experiences in the development of approaches for the successful control of workplace health risks
    C D Money
    ExxonMobil Petroleum and Chemical, Machelen, Belgium
    Ann Occup Hyg 47:533-40. 2003
  10. ncbi Prioritizing industrial chemical hazards
    Veronique D Hauschild
    U S Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground Edgewood Area, Maryland, USA
    J Toxicol Environ Health A 68:857-76. 2005

Detail Information

Publications285 found, 100 shown here

  1. pmc Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical-gene-disease networks
    Allan Peter Davis
    Department of Bioinformatics, The Mount Desert Island Biological Laboratory, Salisbury Cove, ME 04672, USA
    Nucleic Acids Res 37:D786-92. 2009
    ..This wealth of chemical-gene-disease information yields testable hypotheses for understanding the effects of environmental chemicals on human health. CTD is freely available at http://ctd.mdibl.org...
  2. ncbi Genetic susceptibility to environmental toxicants in ALS
    Julia M Morahan
    The Stacey MND Laboratory, Department of Pathology, The University of Sydney, Sydney, New South Wales 2006, Australia
    Am J Med Genet B Neuropsychiatr Genet 144:885-90. 2007
    ..Differences in genes involved in handling toxicants, and interactions between toxicants and these genes, appear to be present in some patients with SALS. This suggests that impaired detoxification mechanisms play a role in SALS...
  3. ncbi Amyotrophic lateral sclerosis and exposure to environmental toxins: an Australian case-control study
    Julia M Morahan
    Department of Pathology, University of Sydney, Sydney, Australia
    Neuroepidemiology 27:130-5. 2006
    ..All positive findings were more statistically significant in males. These findings support those from northern hemisphere studies, indicating that environmental toxins can be risk factors for SALS...
  4. pmc Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community
    Devon C Payne-Sturges
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Environ Health Perspect 112:589-98. 2004
    ..Results from our study underscore the need for a coordinated multimedia approach to exposure assessment for setting public health policy...
  5. pmc Key scientific issues in the health risk assessment of trichloroethylene
    Weihsueh A Chiu
    National Center for Environmental Assessment, Office of Research and Development, U S Environmental Protection Agency, Washington, DC, USA
    Environ Health Perspect 114:1445-9. 2006
    ....
  6. ncbi The exposure data landscape for manufactured chemicals
    Peter P Egeghy
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, United States
    Sci Total Environ 414:159-66. 2012
    ..Exposure to a much broader number of chemicals will need to be measured in order to fully realize the envisioned goal of using exposure information to guide toxicity testing...
  7. pmc Cigarettes sold in China: design, emissions and metals
    RICHARD J O'CONNOR
    Department of Health Behavior, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Tob Control 19:i47-53. 2010
    ....
  8. ncbi Advancing exposure characterization for chemical evaluation and risk assessment
    Elaine A Cohen Hubal
    National Center for Computational Toxicology, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Toxicol Environ Health B Crit Rev 13:299-313. 2010
    ....
  9. ncbi European experiences in the development of approaches for the successful control of workplace health risks
    C D Money
    ExxonMobil Petroleum and Chemical, Machelen, Belgium
    Ann Occup Hyg 47:533-40. 2003
    ....
  10. ncbi Prioritizing industrial chemical hazards
    Veronique D Hauschild
    U S Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground Edgewood Area, Maryland, USA
    J Toxicol Environ Health A 68:857-76. 2005
    ..Users of this or any other chemical priority list are cautioned that the derivation of such lists is largely influenced by subjective decisions and significant variability in chemical-specific data availability and quality...
  11. ncbi Releases from improper chemical mixing, Hazardous Substances Emergency Events Surveillance system, 1996-2001
    Kirsten P Ernst
    Agency for Toxic Substances and Disease Registry, Division of Health Studies Epidemiology and Surveillance Branch, Atlanta, Georgia
    J Occup Environ Med 47:287-93. 2005
    ..To examine the public health consequences of acute hazardous substance releases resulting from the improper mixing of chemicals...
  12. ncbi Hazardous substances releases causing fatalities and/or people transported to hospitals: rural/agricultural vs. other areas
    Zahava Berkowitz
    Agency for Toxic Substances and Disease Registry, Division of Health Studies Epidemiology and Surveillance Branch, Atlanta, GA 30333, USA
    Prehosp Disaster Med 19:213-20. 2004
    ..Therefore, the characteristics of acute hazardous substances releases resulting in death/multiple-victim events occuring in rural/agricultural areas and in all other ..
  13. pmc Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites
    J W Fisher
    Air Force Research Laboratory, Operational Toxicology Branch, Human Effectiveness Directorate, Wright Patterson AFB, OH 45433, USA
    Environ Health Perspect 108:265-73. 2000
    ..TCE PBPK models can be used today to aid in crafting scientifically sound public health decisions for TCE...
  14. pmc A three-stage algorithm to make toxicologically relevant activity calls from quantitative high throughput screening data
    Keith R Shockley
    Biostatistics Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 120:1107-15. 2012
    ....
  15. ncbi Methods of in vitro toxicology
    G Eisenbrand
    University of Kaiserslautern, Department of Chemistry Food Chemistry and Environmental Toxicology, PO Box 3049, D 67653, Kaiserslautern, Germany
    Food Chem Toxicol 40:193-236. 2002
    ..Major weaknesses and strengths of these assay systems are addressed, together with some key issues concerning major research priorities to improve hazard identification and characterisation of food-associated chemicals...
  16. ncbi The public health consequences from acute chlorine releases, 1993-2000
    D Kevin Horton
    Agency for Toxic Substances and Disease Registry, Division of Health Studies Epidemiology and Surveillance Branch, 1600 Clifton Road NE, Mailstop E 31, Atlanta, GA 30333, USA
    J Occup Environ Med 44:906-13. 2002
    ..Data from the Agency for Toxic Substances and Disease Registry's Hazardous Substances Emergency Events Surveillance system were used to conduct a retrospective analysis on the public health ..
  17. ncbi Surveillance of hazardous materials events in 17 states, 1993-2001: a report from the Hazardous Substances Emergency Events Surveillance (HSEES) system
    D Kevin Horton
    Agency for Toxic Substances and Disease Registry, Division of Health Studies, Epidemiology and Surveillance Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Ind Med 45:539-48. 2004
    ..To prevent human exposure and resulting injuries, it is critical to understand the frequency with which these releases occur, the locations involved, the industries associated, and the specific substances being released...
  18. ncbi Assessment of removal of components containing hazardous substances from small WEEE in Austria
    Stefan Salhofer
    BOKU University of Natural Resources and Life Sciences, Institute of Waste Management, Muthgasse 107, Wien, A 1190 Vienna, Austria
    J Hazard Mater 186:1481-8. 2011
    ..WEEE) established by Directive 2002/96/EC provide for the removal of specific components containing hazardous substances. To date, no comparative analysis of removal rates has been undertaken...
  19. ncbi Health effects in Army Gulf War veterans possibly exposed to chemical munitions destruction at Khamisiyah, Iraq: Part I. Morbidity associated with potential exposure
    Clare M Mahan
    Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA
    Mil Med 170:935-44. 2005
    ....
  20. ncbi How important is inadvertent ingestion of hazardous substances at work?
    John W Cherrie
    Institute of Occupational Medicine, Research Park North, Riccarton, Edinburgh, UK
    Ann Occup Hyg 50:693-704. 2006
    Much is known about human exposure to workplace hazardous substances by inhalation and from skin contact, but there has been little systematic research into ingestion of hazardous substances used at work...
  21. ncbi Acute public health consequences associated with hazardous substances released during transit, 1993-2000
    D Kevin Horton
    Agency for Toxic Substances and Disease Registry, Division of Health Studies Epidemiology and Surveillance Branch, 1600 Clifton Road NE, Mailstop E 31, Atlanta, GA 30333, USA
    J Hazard Mater 98:161-75. 2003
    Massive quantities of hazardous substances are transported each day throughout the United States...
  22. ncbi Margins of safety provided by COSHH Essentials and the ILO Chemical Control Toolkit
    Rachael M Jones
    School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    Ann Occup Hyg 50:149-56. 2006
    ..Further, given the small margins observed, we feel it is important that revisions of these systems provide the exposure bands to users, so as to permit evaluation of control technology capture efficiency...
  23. ncbi Medication-associated diethylene glycol mass poisoning: a review and discussion on the origin of contamination
    Joshua G Schier
    Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Public Health Policy 30:127-43. 2009
    ..We discuss existing guidelines and new recommendations for prevention of these incidents...
  24. pmc The assessment of environmental and occupational exposure to hazardous substances by biomonitoring
    Lygia T Budnik
    Ordinariat für Arbeitsmedizin des Universitätsklinikums Hamburg Eppendorf, Zentralinstitut für Arbeitsmedizin und Maritime Medizin, Hamburg, Germany
    Dtsch Arztebl Int 106:91-7. 2009
    ....
  25. ncbi Comparison of powered and conventional air-purifying respirators during simulated resuscitation of casualties contaminated with hazardous substances
    J Schumacher
    GKT School of Medicine, King s College London, St Thomas Campus, Department of Anaesthetics, London SE1 7EH, UK
    Emerg Med J 26:501-5. 2009
    ..Conventional and powered air-purifying respirators may exert a different impact during resuscitation and therefore require evaluation. This will help to improve major incident planning and measures for protecting medical staff...
  26. ncbi Occupational exposure to mineral fibres: analysis of results stored on colchic database
    Edmond Kauffer
    Institut National de Recherche et de Sécurité INRS, Avenue de Bourgogne BP27, 54500 Vandoeuvre les Nancy, France
    Ann Occup Hyg 51:131-42. 2007
    ..inrs.fr) at the beginning of 2007. This database will provide a higher level of detail in activity and workplace description than that which was possible for practical reasons in this paper...
  27. ncbi Safe transport of cyanamide
    Klaus Dieter Wehrstedt
    BAM Federal Institute for Materials Research and Testing, Division II 2 Reactive Substances and Systems, Unter den Eichen 87, D 12205 Berlin, Germany
    J Hazard Mater 170:829-35. 2009
    ..1. Cyanamide, 50% solution in water, can be transported in portable tanks under specific conditions...
  28. pmc Issues in the pharmacokinetics of trichloroethylene and its metabolites
    Weihsueh A Chiu
    National Center for Environmental Assessment, U S Environmental Protection Agency, Washington, DC, USA
    Environ Health Perspect 114:1450-6. 2006
    ..It will be a challenge to develop reliable dosimetry for such cases...
  29. ncbi Patterns of dermal exposure to hazardous substances in European union workplaces
    R Rajan-Sithamparanadarajah
    Health and Safety Executive, Magdalen House, Stanley Precinct, Bootle L20 3QZ, UK
    Ann Occup Hyg 48:285-97. 2004
    ..assessment is a complex task that aims to understand the dynamic interaction between the skin and the hazardous substances present in the surrounding environment...
  30. ncbi Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas
    Perri Zeitz Ruckart
    Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA
    J Hazard Mater 159:53-7. 2008
    ..However, the hurricanes also resulted in unintended hazardous substances releases in the affected states...
  31. ncbi Constituents in tobacco and smoke emissions from Canadian cigarettes
    D Hammond
    Department of Health Studies and Gerontology, University of Waterloo, Ontario, Canada
    Tob Control 17:i24-31. 2008
    ..There is relatively little information available about the chemical constituents of tobacco and individual toxic emissions from cigarettes and other tobacco products...
  32. ncbi Hazardous substances events associated with the manufacturing of chemicals and allied products
    Deana M Manassaram
    Division of Health Studies Epidemiology and Surveillance Branch, Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd NE, Mailstop E 23, Atlanta, GA 30333, USA
    J Hazard Mater 104:123-35. 2003
    This report describes events involving the acute release of hazardous substances reported to the Hazardous Substances Emergency Events Surveillance (HSEES) system for 1993-2000...
  33. pmc Environmental health disparities: a framework integrating psychosocial and environmental concepts
    Gilbert C Gee
    University of Michigan School of Public Health, Department of Health Behavior and Health Education, Ann Arbor, Michigan, USA
    Environ Health Perspect 112:1645-53. 2004
    ..When not counterbalanced by resources, stressors may lead to heightened vulnerability to environmental hazards...
  34. ncbi A structured strategy for assessing chemical risks, suitable for small and medium-sized enterprises
    A Balsat
    School of Public Health, University of Liege, Sart Tilman B23, 4000 Liege, Belgium
    Ann Occup Hyg 47:549-56. 2003
    ..They used their personal judgement and the information contained in manufacturers' Safety Data Sheets to assess the risk...
  35. ncbi Naïve (CD4+CD45RA+) T cell subpopulation is susceptible to various types of hazardous substances in the workplace
    T Tanigawa
    Department of Public Health Medicine, Institute of Community Medicine, University of Tsukuba 1 1 1, Tsukuba shi, Ibaraki Ken, Japan
    Int J Immunopathol Pharmacol 17:109-14. 2004
    To find the most susceptible lymphocyte subpopulation with exposure to various occupational hazardous substances, we reanalyzed our previous data...
  36. pmc Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children
    Joe M Braun
    College of Nursing, University of Wisconsin Milwaukee, Milwaukee, Wisconsin, USA
    Environ Health Perspect 114:1904-9. 2006
    ..The purpose of this study was to examine the association of exposures to tobacco smoke and environmental lead with attention deficit hyperactivity disorder (ADHD)...
  37. ncbi History and evolution of control banding: a review
    David M Zalk
    Lawrence Livermore National Laboratory, Livermore, California 94551, USA
    J Occup Environ Hyg 5:330-46. 2008
    ....
  38. ncbi The Union Carbide disaster in Bhopal: a review of health effects
    V Ramana Dhara
    Arch Environ Health 57:391-404. 2002
    ....
  39. ncbi Toxicological resources for cumulative risk: an example with hazardous air pollutants
    Mary A Fox
    National Research Council, Washington, DC, USA
    Regul Toxicol Pharmacol 40:305-11. 2004
    ..Advancements in toxicological resources will improve cumulative risk assessment. Cumulative risk assessment will reduce risks to the extent that it can be integrated into prevention strategies to track and protect the public's health...
  40. pmc Public health consequences of mercury spills: Hazardous Substances Emergency Events Surveillance system, 1993-1998
    Perri Zeitz
    Epidemiology and Surveillance Branch, Division of Health Studies, Agency for Toxic Substances and Disease Registry, 1600 Clifton Road, MS E 31, Atlanta, GA 30333, USA
    Environ Health Perspect 110:129-32. 2002
    We analyzed data from states that participated in the Hazardous Substances Emergency Events Surveillance (HSEES) system maintained by the Agency for Toxic Substances and Disease Registry to describe the public health consequences of ..
  41. pmc Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks
    Karine Audouze
    Department of Systems Biology, Technical University of Denmark, Center for Biological Sequence Analysis, Lyngby, Denmark
    PLoS Comput Biol 6:e1000788. 2010
    ..The chemical-protein associations are supported through recent published studies, which illustrate the power of our approach that integrates toxicogenomics data with other data types...
  42. ncbi The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays
    Mathieu Vinken
    Department of Toxicology, Vrije Universiteit Brussel VUB, Laarbeeklaan 103, B 1090 Brussels, Belgium
    Mutat Res 659:202-10. 2008
    ..Since selecting an appropriate set of chemicals is a frequent impediment in the early stages of similar research projects, the information provided in this paper might be extremely valuable...
  43. ncbi Evaluation of the control banding method--comparison with measurement-based comprehensive risk assessment
    Haruo Hashimoto
    Medicine and Occupational Health, ExxonMobil Yugen Kaisha, Tokyo, Japan
    J Occup Health 49:482-92. 2007
    ..It should however be noted that the number of workplaces evaluated in this study was small...
  44. ncbi Evaluation of COSHH Essentials for vapor degreasing and bag filling operations
    Rachael M Jones
    School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    Ann Occup Hyg 50:137-47. 2006
    ....
  45. pmc Predicting environmental chemical factors associated with disease-related gene expression data
    Chirag J Patel
    Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA
    BMC Med Genomics 3:17. 2010
    ..Integrating freely-available environment-gene interaction and disease phenotype data would allow hypothesis generation for potential environmental associations to disease...
  46. ncbi Evaluation of inhalation TTC values with the database RepDose
    S E Escher
    Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
    Regul Toxicol Pharmacol 58:259-74. 2010
    ..Based on these analyses two inhalation TTCs for non-genotoxic compounds are proposed: 3.6×10(-3) ppm (180 μg/person/d) for Cramer class 1 and 2.4×10(-5)ppm (4 μg/person/d) for Cramer class 3...
  47. ncbi Evaluation of the HSE COSHH Essentials exposure predictive model on the basis of BAuA field studies and existing substances exposure data
    M Tischer
    Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Unit, Friedrich Henkel Weg 1 25, 44149 Dortmund, Germany
    Ann Occup Hyg 47:557-69. 2003
    ..For small-scale uses of liquids (millilitre scale), e.g. in carpenters' workshops, there were indications that the exposure levels can exceed the predicted ranges. However, it must be noted that the database is rather small...
  48. ncbi Risk management measures for chemicals: the "COSHH essentials" approach
    A N I Garrod
    Health and Safety Executive, Redgrave Court, Bootle, Merseyside, UK
    J Expo Sci Environ Epidemiol 17:S48-54. 2007
    ..It has attracted over 1 million visits to its site since its launch. It offers a common benchmark of good practice for chemical users, manufacturers, suppliers and importers, as well as regulators and health professionals...
  49. pmc Exposure to hazardous substances and male reproductive health: a research framework
    J M Moline
    Department of Community and Preventive Medicine, Mount Sinai Medical Center, New York, New York, USA
    Environ Health Perspect 108:803-13. 2000
    ..to pesticides could diminish or destroy the fertility of workers sparked concern about the effects of hazardous substances on male reproductive health...
  50. ncbi How safe is control banding? Integrated evaluation by comparing OELs with measurement data and using monte carlo simulation
    Martin Tischer
    Division of Hazardous chemicals and biological agents, Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, 44149 Dortmund, Germany
    Ann Occup Hyg 53:449-62. 2009
    ..banding (CB) tool Einfaches Massnahmenkonzept Gefahrstoffe, 'Easy-to-use workplace control scheme for hazardous substances'...
  51. pmc Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal
    D M Burns
    UCSD School of Medicine, San Diego, California, USA
    Tob Control 17:132-41. 2008
  52. ncbi Control banding workshop, 4-5 November 2002, London
    P J Oldershaw
    Ann Occup Hyg 47:531-2. 2003
  53. ncbi Publicly-accessible QSAR software tools developed by the Joint Research Centre
    M Pavan
    Institute for Health and Consumer Protection, Joint Research Centre, European Commission, Ispra Va, Italy
    SAR QSAR Environ Res 19:785-99. 2008
    ..Finally, the JRC QSAR Model Database is a web-based inventory of (Q)SAR models to help industry and government authorities to identify suitable (Q)SARs for chemicals undergoing regulatory review...
  54. pmc Metabolism of trichloroethylene
    L H Lash
    Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Environ Health Perspect 108:177-200. 2000
    ..italic)Key words(/italic): conjugate beta-lyase, cysteine glutathione, cytochrome P450, glutathione (italic)S(/italic)-transferases, metabolism, sex dependence, species dependence, tissue dependence, trichloroethylene...
  55. ncbi A comparative analysis of modeled and monitored ambient hazardous air pollutants in Texas: a novel approach using concordance correlation
    Philip J Lupo
    Division of Epidemiology and Disease Control, The University of Texas School of Public Health, Houston, TX 77030, USA
    J Air Waste Manag Assoc 59:1278-86. 2009
    ..5. On the basis of concordance correlation analysis, the findings indicate there is poorer agreement when compared with the previously applied ad hoc methods to assess comparability between modeled and monitored levels of ambient HAPs...
  56. ncbi Occupational hygiene considerations in the development of a structured approach to select chemical control strategies
    S C Maidment
    Health and Safety Executive, Bootle, Merseyside, U K
    Ann Occup Hyg 42:391-400. 1998
    ..This work was undertaken in a working group established by the Health and Safety Commission's Advisory Committee on Toxic Substances...
  57. ncbi Evaluation of the utility and reliability of COSHH Essentials
    Chris Money
    Ann Occup Hyg 50:642-3; author reply 643-4. 2006
  58. ncbi Evaluation of COSHH Essentials for vapour degreasing and bag-filling operations
    Paul Evans
    Ann Occup Hyg 50:641. 2006
  59. ncbi Evaluation of COSHH essentials: methylene chloride, isopropanol, and acetone exposures in a small printing plant
    Eun Gyung Lee
    Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Ann Occup Hyg 53:463-74. 2009
    ..This was considered a more acceptable alternative to increasing the level of control...
  60. pmc Design of measurement strategies for workplace exposures
    M Topping
    Occup Environ Med 59:788; author reply 788-9. 2002
  61. pmc Evaluation and application of the RD50 for determining acceptable exposure levels of airborne sensory irritants for the general public
    Yu Kuwabara
    Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, California 94612, USA
    Environ Health Perspect 115:1609-16. 2007
    ..Past studies reported good correlations (R(2)) between RD(50)s and the occupational exposure limits, particularly threshold limit values (TLVs)...
  62. doi Health costs of recycling
    Patralekha Chatterjee
    BMJ 337:a296. 2008
  63. ncbi How accurate are the European Union's classifications of chemical substances
    Christina Rudén
    Philosophy Unit, Royal Institute of Technology, Teknikringen 78B, S 100 44 Stockholm, Sweden
    Toxicol Lett 144:159-72. 2003
    ..We propose that the scientific motivations of future classifications be published and that the apparent over- and underclassifications in the present system be either explained or rectified, according to what are the facts in the matter...
  64. ncbi Existing technologies to reduce specific toxicant emissions in cigarette smoke
    R J O'Connor
    Department of Health Behavior, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, USA
    Tob Control 17:i39-48. 2008
    ....
  65. ncbi Acute health effects after exposure to chlorine gas released after a train derailment
    David Van Sickle
    Epidemic Intelligence Service, Air Pollution and Respiratory Health Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Emerg Med 27:1-7. 2009
    ..Pulse oximetry and arterial blood gas analysis provided early indications of outcome severity...
  66. pmc Risk factors for acute chemical releases with public health consequences: Hazardous Substances Emergency Events Surveillance in the U.S., 1996-2001
    Perri Z Ruckart
    Division of Health Studies, Epidemiology and Surveillance Branch, Agency for Toxic Substances and Disease Registry, 1600 Clifton Road, MS E 31, Atlanta, Georgia, USA
    Environ Health 3:10. 2004
    ..reduce and prevent the public health consequences (victims or evacuations) from uncontrolled or illegally released hazardous substances, a more comprehensive analysis is needed to determine risk factors for hazardous materials incidents.
  67. ncbi Maternal occupational risk factors for oral clefts. Occupational Exposure and Congenital Malformation Working Group
    C Lorente
    Inserm U170 Unité de recherches Epidémiologiques et Statistiques sur l Environnement et la Santé, Villejuif, France
    Scand J Work Environ Health 26:137-45. 2000
    ..This study investigated the role of maternal exposures at work during pregnancy in the occurrence of oral clefts...
  68. ncbi Toxicological comments to the discussion about REACH
    Helmut Greim
    Institute of Toxicology and Environmental Hygiene, Technical University of Munich, Hohenbachernstrasse 15 17, 85350 Freising Weihenstephan, Germany
    Arch Toxicol 80:121-4. 2006
    ....
  69. pmc Assessing and intervening on OSH programmes: effectiveness evaluation of the Wellworks-2 intervention in 15 manufacturing worksites
    A D LaMontagne
    Centre for the Study of Health and Society, School of Population Health, University of Melbourne, 207 Bouverie St, Level 4, Melbourne, Victoria 3010, Australia
    Occup Environ Med 61:651-60. 2004
    ....
  70. ncbi Biomarkers of exposure in community settings
    Susan W Metcalf
    Division of Health Assessment and Consultation, Agency for Toxic Substances and Disease Registry, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
    J Toxicol Environ Health A 67:715-26. 2004
    ..In spite of these limitations, the use of biomonitoring is finding wider application in many scientific disciplines. Recent advances in analytical techniques are expanding the utility of biomarker testing in public health investigations...
  71. ncbi Health risk communication using comparative risk analyses
    Pamela R D Williams
    ChemRisk, 4775 Walnut Street, Suite 1B, Boulder, Colorado 80301, USA
    J Expo Anal Environ Epidemiol 14:498-515. 2004
    ..The evolving field of risk communication is also discussed, including ongoing research on public risk perceptions and alternative methods for communicating risk magnitudes and data uncertainties...
  72. ncbi Improving the prevention and control of hazardous substance exposures: a randomized controlled trial in manufacturing worksites
    Anthony D LaMontagne
    Centre for Health and Society, School of Population Health, University of Melbourne, Melbourne, Vic, Australia
    Am J Ind Med 48:282-92. 2005
    ..New measures of exposure prevention (EP) activity were used to evaluate the effectiveness of a 16-month management-focused intervention addressing hazardous substance exposures in manufacturing work settings...
  73. ncbi 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System
    William A Watson
    Am J Emerg Med 22:335-404. 2004
  74. ncbi Baltic Sea hazardous substances management: results and challenges
    Henrik Selin
    Massachusetts Institute of Technology, Dept of Urban Studies and Planning, Cambridge 02139, USA
    Ambio 33:153-60. 2004
    The introduction into the Baltic Sea of hazardous substances that are persistent, bioaccumulate, and are toxic is an important environmental and human health problem...
  75. ncbi Inhalation of hazardous air pollutants from environmental tobacco smoke in US residences
    William W Nazaroff
    Department of Civil and Environmental Engineering, University of California, Berkeley, California 94720 1710, USA
    J Expo Anal Environ Epidemiol 14:S71-7. 2004
    ..It is an important cause of intake for acetaldehyde, acrolein, and formaldehyde, and a significant contributor to intake for benzene...
  76. pmc Agricultural chemical exposures and birth defects in the Eastern Cape Province, South Africa: a case-control study
    Gudrun A Heeren
    Department of Public Health, Cecilia Makiwane Hospital, Mdantsane, P, O, Box 691, East London 5200, South Africa
    Environ Health 2:11. 2003
    ..In this paper we investigate associations between exposure to agricultural chemicals and certain birth defects. Few such studies have been undertaken in the developing world previously...
  77. ncbi Developing COSHH Essentials: dermal exposure, personal protective equipment and first aid
    A N I Garrod
    Health and Safety Executive, Magdalen House, Stanley Precinct, Bootle L20 3QZ, UK
    Ann Occup Hyg 47:577-88. 2003
    ..Planning for emergencies is an important facet of risk control. Proposals are outlined to band chemical hazards for emergency planning according to a minimum of information, i.e. the danger symbol on a product label...
  78. pmc Global surveillance for chemical incidents of international public health concern
    B Olowokure
    Health Protection Agency Regional Surveillance Unit West Midlands, Regional Epidemiology Unit, Heartlands Hospital, Birmingham, England
    Bull World Health Organ 83:928-34. 2005
    ..This report describes the frequency, nature and geographical location of acute chemical incidents of potential international concern from August 2002 to December 2003...
  79. ncbi Biomonitoring: is body burden relevant to public health?
    Dennis Paustenbach
    ChemRisk, Inc, 25 Jessie Street at Ecker Square, Suite 1800, San Francisco, CA 94105, USA
    Regul Toxicol Pharmacol 44:249-61. 2006
    ..We present suggestions for contextualizing biomonitoring results in order to provide the public with the tools to distinguish genuine health risks from trivial ones...
  80. ncbi An evaluation of spatial and multivariate covariance among childhood cancer histotypes in Texas (United States)
    James A Thompson
    Department of Large Animal Clinical Science, Texas A and M University, College Station, TX 77843 4475, USA
    Cancer Causes Control 18:105-13. 2007
    ..Results will be valuable for selecting appropriate models to support more specific etiologic studies of environmental factors for childhood cancer...
  81. ncbi REACH, non-testing approaches and the urgent need for a change in mind set
    G Schaafsma
    TNO Quality of Life, Department of Food and Chemical Risk Analysis, P O Box 360, 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 53:70-80. 2009
    ..Only such an approach will make it possible to obtain a sufficient level of information within the time frame of REACH. A much more intensive dialogue between stakeholders is necessary...
  82. ncbi Analyzing exposure of school children to accidental releases of hazardous substances
    J Chakraborty
    University of South Florida, 4202 East Fowler Avenue, SOC 107, Tampa, FL 33620, USA
    J Expo Anal Environ Epidemiol 11:269-78. 2001
    ..are to: (a) demonstrate a methodology for identifying areas potentially exposed to accidental releases of hazardous substances in a large metropolitan region (Hillsborough County, Florida); (b) examine the number and type of schools ..
  83. pmc Improving disclosure and consent: "is it safe?": new ethics for reporting personal exposures to environmental chemicals
    Julia Green Brody
    Silent Spring Institute, Newton, MA 0245, USA
    Am J Public Health 97:1547-54. 2007
    ..Our discussion is informed by our experience with 120 women in a study of 89 pollutants in homes and by interviews with other researchers and institutional review board staff...
  84. ncbi Will biomonitoring change how we regulate toxic chemicals?
    Richard Jackson
    National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Law Med Ethics 30:177-83. 2002
    ....
  85. ncbi Validation successes: chemicals
    Horst Spielmann
    National Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments ZEBET, Federal Institute for Health Protection of Consumers and Veterinary Medicine BgVV, Diedersdorfer Weg 1, 12277 Berlin, Germany
    Altern Lab Anim 30:33-40. 2002
    ....
  86. ncbi Non-Hodgkin's lymphoma and occupational exposure to chemicals in Canada. Canadian Cancer Registries Epidemiology Research Group
    Y Mao
    Cancer Bureau, Health Canada, Ottawa, Ontario, Canada
    Ann Oncol 11:69-73. 2000
    ..The incidence of non-Hodgkin's lymphoma (NHL) has been increasing in Canada. This study assessed the effect of occupational exposure to specific chemicals on the risk of NHL...
  87. ncbi Agency for Toxic Substances and Disease Registry's 1997 priority list of hazardous substances. Latent effects--carcinogenesis, neurotoxicology, and developmental deficits in humans and animals
    S R Ostrowski
    Division of Toxicology, Agency for Toxic Substances and Disease Registry, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    Toxicol Ind Health 15:602-44. 1999
    ..The review was limited to the top 50 substances listed on ATSDR's 1997 Priority List of Hazardous Substances (Priority List)...
  88. ncbi Application of health information to hazardous air pollutants modeled in EPA's Cumulative Exposure Project
    J C Caldwell
    U S Environmental Protection Agency Office of Air and Radiation, Research Triangle Park, North Carolina 27711, USA
    Toxicol Ind Health 14:429-54. 1998
    ....
  89. ncbi Hazardous substances emergency events in the agriculture industry and related services in four mid-western states
    Zahava Berkowitz
    Agency for Toxic Substance and Disease Registry, Division of Health Studies, Epidemiology and Surveillance Branch, 1600 Clifton Rd, MS E 31, Atlanta, GA 30333, USA
    J Occup Environ Med 44:714-23. 2002
    Analysis of Hazardous Substances Emergency Events Surveillance data reported from 14 participating states between 1993 and 1998 found that acute releases are seasonal...
  90. ncbi Toxic fear: the management of uncertainty in the wake of the Amsterdam air crash
    A Boin
    Department of Public Administration, Crisis Research Center, Leiden University, P O Box 9555, 2300 RB Leiden, The Netherlands
    J Hazard Mater 88:213-34. 2001
    ..The evolution of a "toxic fear" among citizens is documented and the social psychology of crisis management in the aftermath is examined...
  91. pmc Evaluating noncancer effects of trichloroethylene: dosimetry, mode of action, and risk assessment
    H A Barton
    K S Crump Group, Inc, ICF Consulting, Research Triangle Park, NC, USA
    Environ Health Perspect 108:323-34. 2000
    ..Incorporation of pharmacokinetics and pharmacodynamics can result in values that differ significantly from those obtained with the default methods...
  92. ncbi Hazardous materials events: evaluation of transport to health care facility and evacuation decisions
    J L Burgess
    Environmental and Occupational Health Unit, University of Arizona Prevention Center, Tucson, AZ, USA
    Am J Emerg Med 19:99-105. 2001
    ..Further research is needed to determine if these factors also predict need for medical care or removal from exposure, and to develop evidence-based prehospital care protocols for hazardous materials exposure victims...
  93. ncbi Prioritization of NTP reproductive toxicants for field studies
    W J Moorman
    National Institute for Occupational Safety and Health NIOSH, 4676 Columbia Pkwy, Cincinnati OH 45226, USA
    Reprod Toxicol 14:293-301. 2000
    ..The chemicals with the highest priority for field study were: dibutyl phthalate, boric acid, tricresyl phosphate, and N, N-dimethylformamide...
  94. ncbi Development of acute exposure guideline levels for airborne exposures to hazardous substances
    Daniel Krewski
    University of Ottawa, Ottawa, Ont, Canada
    Regul Toxicol Pharmacol 39:184-201. 2004
    b>Hazardous substances can be released into the atmosphere due to industrial and transportation accidents, fires, tornadoes, earthquakes, and terrorists, thereby exposing workers and the nearby public to potential adverse health effects...
  95. ncbi Development of a globally harmonized system for hazard communication
    Jennifer C Silk
    Occupational Safety and Health Administration, Directorate of Standards and Guidance, Washington, DC 20210, USA
    Int J Hyg Environ Health 206:447-52. 2003
    ..The purpose of this discussion is to describe the work to develop the system, the primary components of the GHS, and efforts to promote implementation...
  96. ncbi Land use planning in India
    J P Gupta
    Department of Chemical Engineering, Indian Institute of Technology, Kanpur 208026, India
    J Hazard Mater 130:300-6. 2006
    ..level of industrialization in different parts, need for creation of jobs, eco-sensitive regions, tribal regions, historical monuments, etc. This paper discusses the current scene in India and the near future aspects...
  97. ncbi The development of an audit technique to assess the quality of safety barrier management
    Frank Guldenmund
    Safety Science Group, Delft University of Technology, Netherlands
    J Hazard Mater 130:234-41. 2006
    ..However, this strength is also its limitation, since the full safety management system is not covered with the technique. Finally, some preliminary experiences obtained from several test sites are compiled and discussed...
  98. ncbi Environmental vulnerability assessment in the vicinity of an industrial site in the frame of ARAMIS European project
    J Tixier
    Industrial Risk and Natural Hazard Department, LGEI, Ecole des Mines d Alès, 6 avenue de Clavières, 30319 Ales Cedex, France
    J Hazard Mater 130:251-64. 2006
    ..The result is an operational tool allowing competent authorities, industrialists and risk experts to assess the vulnerability of the area surrounding an industrial site...
  99. ncbi The use of generic failure frequencies in QRA: the quality and use of failure frequencies and how to bring them up-to-date
    H I Beerens
    RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    J Hazard Mater 130:265-70. 2006
    ..Furthermore, the possibility is presented how these generic data can be revised and updated...
  100. ncbi Quantifying the influence of safety management on the reliability of safety barriers
    Nijs Jan Duijm
    Risø National Laboratory, Systems Analysis Department, P O Box 49, DK 4000 Roskilde, Denmark
    J Hazard Mater 130:284-92. 2006
    ..A preliminary set of weight factors is presented with some examples of resulting reductions in reliability--this demonstration confirms that the set of weight factors needs further development...
  101. ncbi Acute health reference values: overview, perspective, and current forecast of needs
    George M Woodall
    U S Environmental Protection Agency, National Center for Environmental Assessment, Research Triangle Park, North Carolina, USA
    J Toxicol Environ Health A 68:901-26. 2005
    ..S. Environmental Protection Agency (EPA) to develop a set of less-than-lifetime reference values, along with a discussion of how that effort fits with the existing sets of values described in the prior sections...

Research Grants70

  1. MOLECULAR MECHANISMS OF COMPLEX MIXTURE TOXICITY
    Alvaro Puga; Fiscal Year: 2013
    ..environmental co-contaminant with PAHs, and benzo[a]pyrene (BaP), a prototypical PAH, are among the top 20 hazardous substances in the ATSDR/EPA priority list...
  2. The effect of trichloroethylene exposure on adverse pregnancy outcomes
    Iman Hassan; Fiscal Year: 2013
    ..TCE is a common drinking water contaminant, and is currently ranked 16th on the Superfund Priority List of Hazardous Substances [2]...
  3. Moffitt Skin Cancer SPORE
    Jeffrey S Weber; Fiscal Year: 2013
    ....
  4. THE EFFECT OF DIOXINS ON GLUCOSE HOMEOSTASIS IN MURINE TESTES
    KENAN RIFAT OMURTAG; Fiscal Year: 2013
    ..This research will help us better understand how such environmental exposures may affect the male reproductive tract. ..
  5. Role of Physico-chemical Properties in the Reprotoxicity of Inhaled Cd NP.
    JUDITH TERRY ZELIKOFF; Fiscal Year: 2010
    ....
  6. FOXO1 Inhibition in Genotoxic Stress Response and Prostate Cancer Survival
    Haojie Huang; Fiscal Year: 2013
    ..Findings from this study will not only enhance our understanding of age-related prostate cancinogenesis, but could also provide new molecular targets to devise strategies for prostate cancer prevention and therapy. ..
  7. Environmental Determinants of Cognitive Aging in the WHI Memory Study
    Jiu Chiuan Chen; Fiscal Year: 2013
    ..investigate exposures to ambient air pollutants as novel environmental determinants of cognitive aging to better understand the later-life environmental influence on brain aging and subsequent risk of cognitive impairment and dementia ..
  8. Light-Alarming Personal Noise Dosimeter System
    ALEXANDER MILOVANOV; Fiscal Year: 2013
    ..abstract_text> ..
  9. Phosphodiesterase-3B signaling in the Hypothalamus and Obesity
    Abhiram Sahu; Fiscal Year: 2013
    ..Overall, these studies will define the critical role of PDE3B signaling in the hypothalamus in the context of the physiology and pathophysiology of energy homeostasis. ..
  10. New Personal Sampling Methods that Conform to an Aerosol Deposition Convention
    DARRAH KAYE SLEETH; Fiscal Year: 2013
    ..I have a PhD in Industrial Health and an MPH in Industrial Hygiene &Hazardous Substances, both from the University of Michigan...
  11. Liquid Crystal-Based End-of-Service-Life-Indicator for Toluene Vapor
    BHARAT R ACHARYA; Fiscal Year: 2011
    ....
  12. Fruit exosome-like particles for therapeutic delivery of extracellular miRNAs
    Huang Ge Zhang; Fiscal Year: 2013
    ..We will accomplish this in our study by knock-out and knock-in strategies. ..
  13. Arsenic Induced Miotic Arrest Associated Apoptosis
    J Christopher States; Fiscal Year: 2009
    ....
  14. Circadian Clock of the Paraventricular Nucleus
    Charles J Weitz; Fiscal Year: 2012
    ..Ultimately, the work proposed here could lead to the development of new treatments for diabetes and obesity. ..
  15. Receptor-based developmental and reproductive toxicity of Superfund chemicals
    David M Ozonoff; Fiscal Year: 2013
    ..of disturbances of reproductive and developmental processes, including aging, from exposures to hazardous substances in the environment...
  16. Renovation and Infrastructure Upgrade of Laboratory Research Wing at Johns Hopkin
    Michael J Klag; Fiscal Year: 2010
    ..This project will help ensure that JHSPH continues to pioneer discovery that promotes the public's health, both now and in the future. ..
  17. CBH Partnership on Environmental Public Health Exploration and Mitigation
    Chensheng Lu; Fiscal Year: 2012
    ..In an effort to reduce residents', particularly children's exposure to pesticides, we plan to evaluate the effectiveness of Integrated Pest Management program conducted by the Boston Public Housing Authority. ..
  18. MicroRNA-mediated Regulation in Mammalian Skin
    Rui Yi; Fiscal Year: 2013
    ..The knowledge gained from these studies under normal development condition will also pave the way to investigate miRNA's roles in human diseases e.g. skin cancers where regulatory networks go awry. ..
  19. Environmental Mutagen Society 2011 Annual Meeting
    CATHERINE G B KLEIN; Fiscal Year: 2011
    ..The meetings also provide a forum in which students, postdoctoral fellows, and early career investigators can share information with established scientists through formal scientific sessions and informal interactions. ..
  20. Mechanisms of Environmental Stress Affecting Corneal Epithelial Wound Healing
    Luo Lu; Fiscal Year: 2011
    ..Thus, studies of UV stress-induced signaling events provide significant insight for understanding the mechanisms that underlie the corneal epithelial wound healing processes from damages caused by environmental insults. ..
  21. Molecular Pathways to Pathogenesis in Toxicology
    Robert C Smart; Fiscal Year: 2013
    ....
  22. Guide RNA Binding Complex
    RUSLAN AFASIZHEV; Fiscal Year: 2013
    ....
  23. Summer Research Experience for Veterinary Students
    Mark L Lawrence; Fiscal Year: 2010
    ....
  24. Novel regulators of skin development and Foxn1 function
    Janice L Brissette; Fiscal Year: 2012
    ..Over the long term, the project will provide insight into how skin may be clinically generated or manipulated, thus facilitating methods for the replacement or repair of damaged and diseased skin. ..
  25. EPIGENETIC TRANSGENERATIONAL ENDOCRINE DISRUPTOR ACTIONS
    Michael K Skinner; Fiscal Year: 2013
    ..The proposed research will more thoroughly investigate this epigenetic transgenerational phenomenon and elucidate the molecular mechanisms involved. ..
  26. Nucleotide Regulation of Apaf-1 Apoptosome and Apoptosis
    Dean G Tang; Fiscal Year: 2010
    ..The accomplishment of the proposed goals will greatly advance our understanding of apoptosome regulation in vivo and help us understand cellular response to environmental stress and cancer cell response to anti- tumor therapeutics. ..
  27. Epigenetic Regulation by Large Non-Coding RNAs in the p53 Mediated DNA Damage Res
    JOHN LOUIS RINN; Fiscal Year: 2013
    ..These datasets will then be used for numerous computational analyses to find common sequence and structural motifs within lincRNAs that may drive their epigenetic and cellular regulatory roles. ..
  28. 2013 Environmental Mutagen Society Annual Meeting
    Mats Ljungman; Fiscal Year: 2013
    ..EMS member speakers cover their expenses for participation in the conference, thus expenses for their participation are not requested in this application. ..
  29. Arsenic Phytosensors
    Mark P Elless; Fiscal Year: 2010
    ..The plant-based sensors will provide continuous real-time indication of arsenic in soils locatedin residential and industrial settings so as to limit exposure of this known carcinogen to humans. ..
  30. TOXIC SUBSTANCES IN THE ENVIRONMENT
    Martyn T Smith; Fiscal Year: 2013
    ..aim to develop advanced techniques for the detection, assessment, and evaluation of the effect of hazardous substances on human health and improve methods to assess the risks to human health presented by benzene, arsenic, ..
  31. Environmental Mutagen Society 2012 Annual Meeting-Trainee and Speaker Support
    Mats Ljungman; Fiscal Year: 2012
    ..The meetings also provide a forum in which students, postdoctoral fellows, and early career investigators can share information with established scientists through formal scientific sessions and informal interactions. ..
  32. The Synergistic effect and Mechanism of Arsenic on Chromium (VI) Carcinogenesis
    Hong Xie; Fiscal Year: 2012
    ..This research will investigate how arsenic disrupts DNA damage repair which results in enhancement of Cr(VI)-induced lung cancer. ..
  33. Research Training Program in Environmental Pediatrics
    Robert O Wright; Fiscal Year: 2013
    ..All 4 graduates are pursuing academic careers in environmental pediatrics. Fellows and graduates have published over 30 papers. One graduate is a Lead Investigator in the NCS. Another has secured an NIH K99 award. ..
  34. TRAINING GRANT IN ENVIRONMENTAL TOXICOLOGY
    John M Essigmann; Fiscal Year: 2013
    ..Our approaches involve measurement of risk, mining of complex biological data, modeling of systems exposed to environmental agents, and manipulation of systems to modulate risk. ..
  35. Compact, wearable monitor for continuous detection of nitrogen dioxide in mines
    TIMOTHY GEORGE BURLAND; Fiscal Year: 2013
    ..In the long term, LC-based DRI's have the potential to be a broadly applicable platform technology, offering multi-analyte monitoring in the workplace. ..
  36. Climate impact on coastal ecosystem methylmercury: human exposure implications
    Celia Y Chen; Fiscal Year: 2013
    ..provided by applicant) Mercury (Hg) is the third most important contaminant on the CERCLA Priority List of Hazardous Substances (2011) and its organic and toxic form, methyl mercury (MeHg), is a potent toxin with human health effects...
  37. Field Deployable Vapor Intrusion Monitor
    Bikas Vaidya; Fiscal Year: 2011
    ....
  38. Ex Vivo Expansion of Human Limbal Stem Cells for Transplantation
    Sophie Deng; Fiscal Year: 2013
    ..This will eliminate any potential permanent side effects or toxicity. The proposed translational research is significant, because the results from any of the two aims can be readily adapted for clinical development. ..
  39. The HSPH Education and Research Center of Occupational Safety and Health
    David C Christiani; Fiscal Year: 2013
    ..Some industrial hygiene Master's candidates are identified for specialization in hazardous substances (Hazardous Substances Academic Training)...
  40. EMS 40th Annual Meeting - Student and New Investigator Travel and Invited Non-Mem
    Michael Plewa; Fiscal Year: 2009
    ..However, it is necessary to assist with travel expenses for invited non-member speakers, who provide the cross-fertilization of ideas necessary for a world-class meeting. ..
  41. Reducing Pesticide Exposure in Farmworker Families: Research to Practice
    Sara A Quandt; Fiscal Year: 2010
    ..Because pesticide exposure has long-term health effects on children and adults, this program can result in decreases in the neurological, cancer, and developmental defects that have been associated with exposure. ..
  42. Safety and Health Management of Hazards Associated with Emerging Technologies.
    Robert F Herrick; Fiscal Year: 2013
    ..prepare professional practitioners and researchers to address the evaluation, handling, and management of hazardous substances and conditions associated with emerging technologies such as nanotechnology, energy exploration and ..
  43. North Carolina Occupational Safety and Health Education and Research Center
    BONNIE M ROGERS; Fiscal Year: 2013
    ..Outreach to the local occupational safety and health community is an integral part of the NC OSHERC. ..
  44. LSU Superfund Research Center - Environmentally Persistent Free Radicals
    Barry Dellinger; Fiscal Year: 2013
    ..in contaminated soils at a Superfund wood-treating site and the fly-ash produced from incineration of hazardous substances. At high concentrations in thermal treatment devices, the EPFRs also promote the formation of new molecular ..
  45. Environmental Mutagen Society 2010 Annual Meeting
    Jeffrey L Schwartz; Fiscal Year: 2010
    ..External support for invited speaker travel and trainee travel awards is required to achieve the scientific objectives, training and outreach goals of EMS. ..
  46. Bisphenol A and the Metabolic Syndrome: Focus on Adipose Tissue Functions
    Nira Ben-Jonathan; Fiscal Year: 2013
    ..abstract_text> ..
  47. Impact of Health Department Worker Safety Training on Health Impacts after Sandy
    Michael J Reilly; Fiscal Year: 2013
    ..These courses could be delivered by health departments nationwide in response to a sudden disaster. ..
  48. Center for Enviromental Health in Northern Manahattan
    Regina M Santella; Fiscal Year: 2013
    ..much research is focused on a disadvantaged community that receives disproportionally high exposure to hazardous substances in NYC, other projects study effects of environmental exposures around the world...
  49. Internet-Based STI/HIV Prevention for HIV+ Internet Users
    Dean G Cruess; Fiscal Year: 2013
    ....
  50. Decision Making at the cutting edge of Environmental Health: Red Tides
    Jamie L Studts; Fiscal Year: 2011
    ..This innovative research will provide information that can be used to facilitate good decision making in the face of these and other environmental health hazards, and thus directly improve public health. ..
  51. Ninth Annual Conference on Urban Environmental Health
    Susan Klitzman; Fiscal Year: 2010
    ..Perspectives and lessons from different countries can be valuable to share. We have now held six prior conferences that have been well attended and look forward to continuing this series. ..
  52. Human N6AMT1 and Its Regulation of Arsenic Biomethylation and Toxicity
    Xuefeng Ren; Fiscal Year: 2013
    ....
  53. Support for Preparation of National Toxicology (NTP) Nomination Background Inform
    Marcus A Jackson; Fiscal Year: 2010
    ..The NTP nomination review and selection process is described in more detail at http://ntp.niehs.nih.gov/go/156. ..
  54. Support for Preparation of National Toxicology (NTP) Nomination Background Inform
    Marcus A Jackson; Fiscal Year: 2009
    ..The NTP nomination review and selection process is described in more detail at http://ntp.niehs.nih.gov/go/156...
  55. Developmental neurotoxicity pathways for high throughput testing by metabolomics
    Thomas Hartung; Fiscal Year: 2012
    ..Demanding animal tests have been devised, but because of low frequencies of hazardous substances and manifestations, as well as complex underlying mechanisms, limitations of current approaches are ..
  56. BioCARS: A Synchroton Structural Biology Resource
    JOHN KEITH MOFFAT; Fiscal Year: 2011
    ..Yet others, particularly the transient structures, provide a novel view of mechanisms of action, and thus underlie the development of more effective therapeutic agents. ..
  57. Unattended Vapor Intrusion Monitor
    Sanjay V Patel; Fiscal Year: 2012
    ..The system addresses needs as described by the NIEHS Hazardous Substances Detection and Remediation Program...
  58. Occupational Health for All: From Research to Practice
    BONNIE M ROGERS; Fiscal Year: 2012
    ..The most common workplace illnesses are cancers from exposure to hazardous substances, musculoskeletal diseases, respiratory diseases, hearing loss, circulatory diseases and communicable ..
  59. Combined Undergraduate and Graduate Training Program
    ROGER C JENSEN; Fiscal Year: 2013
    ..The graduates tend to stay in the field and spend their entire career advancing the safety and health of people at work. ..
  60. Qualitative methods for public health research: HIV/STI prevention in China
    Kathryn E Muessig; Fiscal Year: 2010
    ..Collaborating with Chinese researchers will also continue to build U.S.-China diplomatic research relationships for the benefit of better addressing public health concerns in both countries. ..
  61. Role of RPA Hyperphosphorylation in DNA Damage Responses
    MOISES ALEJANDRO SERRANO; Fiscal Year: 2012
    ..Do not use suffixes such as 2a, 2b. Kirschstein-NRSA Individual Fellowship Application NAME OF APPLICANT (Last, first, middle initial) Serrano, Moises A (To be completed by applicant - follow PHS 416-1 instructions) 18. ..
  62. Community Mapping of Environmental Hazards and Barriers in an Immigrant Populatio
    Peggy Reynolds; Fiscal Year: 2010
    ....
  63. SUPERFUND TOXIC SUBSTANCES--EXPOSURE AND DISEASE
    Karl Kelsey; Fiscal Year: 2006
    Our theme is the understanding and assessment of risk to human health from exposure to hazardous substances. We approach this theme from the perspective of an interdisciplinary team that integrates exposure assessment, biologic ..
  64. GENOTOXICITY IN CYP1A2 DEFICIENT TRANSGENIC MICE
    Daniel Nebert; Fiscal Year: 2002
    ..S. population. ..
  65. INCREASING COLORECTAL CANCER SCREENING AMONG CARPENTERS
    Isaac Lipkus; Fiscal Year: 2003
    ..Such interventions are especially needed among blue-collar workers who are more likely to be exposed to environmental carcinogens and engage in behavioral risk factors that increase CRC risk. ..
  66. Antibiofilm tubing to reduce occupational exposure to biohazards in dentistry
    Yuyu Sun; Fiscal Year: 2009
    ..In addition, the antibiofilm plastic tube materials to be developed in this study may find applications in other clinically important surfaces, which will make significant contributions to a better and safer healthcare environment. ..
  67. Innovations to Inform Occupational Disease Etiology Using Biomonitoring Methods
    JO ANNA SHIMEK; Fiscal Year: 2009
    ..Finally, a biomarker of susceptibility will be analyzed using a mutagen sensitivity assay for these compounds, and results will be correlated with the relative cumulative exposure scores. ..
  68. IMPROVING ENVIRONMENTAL QUALITY AND HAZARD CONTAINMENT
    Maarten Bosland; Fiscal Year: 2004
    ..Animal Facility (DEMSAF) of NYU School of Medicine and to improve the facilities for experiments with hazardous substances. The first major goal is to bring the animal facility in compliance with standards (PHS Guide, AAALAC) for ..
  69. REPRODUCTIVE TOXICOLOGY AND EPIDEMIOLOGY
    Bill Lasley; Fiscal Year: 2003
    ..abstract_text> ..
  70. Organic Solvent Mixtures & Neuropsychological Outcomes
    Ellen Kirrane; Fiscal Year: 2002
    ..The exposure assessment piece proposed in this project is an ideal addition to the cohort study and will provide valuable information for evaluating the risks from continuous and intermittent exposure to commonly used organic solvents. ..