pesticides

Summary

Summary: Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.

Top Publications

  1. ncbi Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease
    Todd B Sherer
    Center for Neurodegenerative Disease, Rollins School of Public Health, Atlanta, Georgia 15213, USA
    J Neurochem 100:1469-79. 2007
  2. pmc High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health
    Christopher A Mullin
    Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS ONE 5:e9754. 2010
  3. ncbi The sublethal effects of pesticides on beneficial arthropods
    Nicolas Desneux
    Department of Entomology, University of Minnesota, St Paul, Minnesota 55108, USA
    Annu Rev Entomol 52:81-106. 2007
  4. pmc Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children
    Maryse F Bouchard
    University of California Berkeley, Center for Environmental Research and Children s Health, School of Public Health, Berkeley, California 94704, USA
    Environ Health Perspect 119:1189-95. 2011
  5. pmc Seven-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide
    Virginia Rauh
    Heilbrunn Center for Population and Family Health, Mailman School of Public Health, New York, NY 10032 USA
    Environ Health Perspect 119:1196-201. 2011
  6. ncbi Genotoxicity of pesticides: a review of human biomonitoring studies
    Claudia Bolognesi
    Toxicological Evaluation Unit, National Cancer Research Institute, Genova, Italy
    Mutat Res 543:251-72. 2003
  7. pmc The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants
    A M Soto
    Tufts University School of Medicine, Department of Anatomy and Cellular Biology, Boston, MA 02111, USA
    Environ Health Perspect 103:113-22. 1995
  8. ncbi Wildlife ecotoxicology of pesticides: can we track effects to the population level and beyond?
    Heinz R Köhler
    Animal Physiological Ecology, Institute of Evolution and Ecology, University of Tubingen, Tubingen, Germany
    Science 341:759-65. 2013
  9. pmc Dopamine transporter genetic variants and pesticides in Parkinson's disease
    Beate R Ritz
    Department of Epidemiology, Center for Occupational and Environmental Health, UCLA School of Public Health, University of California at Los Angeles, Los Angeles, California 90095 1772, USA
    Environ Health Perspect 117:964-9. 2009
  10. pmc Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes
    Duk Hee Lee
    Department of Preventative Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
    PLoS ONE 6:e15977. 2011

Detail Information

Publications362 found, 100 shown here

  1. ncbi Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease
    Todd B Sherer
    Center for Neurodegenerative Disease, Rollins School of Public Health, Atlanta, Georgia 15213, USA
    J Neurochem 100:1469-79. 2007
    ..the in vitro toxicity and mechanism of action of several putative complex I inhibitors that are commonly used as pesticides. The rank order of toxicity of pesticides to neuroblastoma cells was pyridaben > rotenone > fenpyroximate > ..
  2. pmc High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health
    Christopher A Mullin
    Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
    PLoS ONE 5:e9754. 2010
    ..A broad survey of pesticide residues was conducted on samples from migratory and other beekeepers across 23 states, one Canadian province and several agricultural cropping systems during the 2007-08 growing seasons...
  3. ncbi The sublethal effects of pesticides on beneficial arthropods
    Nicolas Desneux
    Department of Entomology, University of Minnesota, St Paul, Minnesota 55108, USA
    Annu Rev Entomol 52:81-106. 2007
    Traditionally, measurement of the acute toxicity of pesticides to beneficial arthropods has relied largely on the determination of an acute median lethal dose or concentration...
  4. pmc Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children
    Maryse F Bouchard
    University of California Berkeley, Center for Environmental Research and Children s Health, School of Public Health, Berkeley, California 94704, USA
    Environ Health Perspect 119:1189-95. 2011
    Organophosphate (OP) pesticides are neurotoxic at high doses. Few studies have examined whether chronic exposure at lower levels could adversely affect children's cognitive development.
  5. pmc Seven-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide
    Virginia Rauh
    Heilbrunn Center for Population and Family Health, Mailman School of Public Health, New York, NY 10032 USA
    Environ Health Perspect 119:1196-201. 2011
    ....
  6. ncbi Genotoxicity of pesticides: a review of human biomonitoring studies
    Claudia Bolognesi
    Toxicological Evaluation Unit, National Cancer Research Institute, Genova, Italy
    Mutat Res 543:251-72. 2003
    b>Pesticides constitute a heterogeneous category of chemicals specifically designed for the control of pests, weeds or plant diseases...
  7. pmc The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants
    A M Soto
    Tufts University School of Medicine, Department of Anatomy and Cellular Biology, Boston, MA 02111, USA
    Environ Health Perspect 103:113-22. 1995
    ....
  8. ncbi Wildlife ecotoxicology of pesticides: can we track effects to the population level and beyond?
    Heinz R Köhler
    Animal Physiological Ecology, Institute of Evolution and Ecology, University of Tubingen, Tubingen, Germany
    Science 341:759-65. 2013
    ..However, the productive arable area has increased by just 10%; thus the increased use of pesticides has been a consequence of the demands of human population growth, and its impact has reached global significance...
  9. pmc Dopamine transporter genetic variants and pesticides in Parkinson's disease
    Beate R Ritz
    Department of Epidemiology, Center for Occupational and Environmental Health, UCLA School of Public Health, University of California at Los Angeles, Los Angeles, California 90095 1772, USA
    Environ Health Perspect 117:964-9. 2009
    Research suggests that independent and joint effects of genetic variability in the dopamine transporter (DAT) locus and pesticides may influence Parkinson's disease (PD) risk.
  10. pmc Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes
    Duk Hee Lee
    Department of Preventative Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
    PLoS ONE 6:e15977. 2011
    ..The current study examined if low dose POPs predicted future adiposity, dyslipidemia, and insulin resistance among controls without diabetes in that study...
  11. pmc Persistent organic pollutant exposure leads to insulin resistance syndrome
    Jérôme Ruzzin
    National Institute of Nutrition and Seafood Research NIFES, Bergen, Norway
    Environ Health Perspect 118:465-71. 2010
    ..However, experimental evidence demonstrating a causal link between POPs and the development of insulin resistance is lacking...
  12. ncbi A cocktail of contaminants: how mixtures of pesticides at low concentrations affect aquatic communities
    Rick A Relyea
    Department of Biological Sciences, University of Pittsburgh, 101 Clapp Hall, Pittsburgh, PA 15260, USA
    Oecologia 159:363-76. 2009
    ..mesocosms, I examined each pesticide alone, a mix of insecticides, a mix of herbicides, and a mix of all ten pesticides. Individual pesticides had a wide range of direct and indirect effects on all trophic groups. For some taxa (i.e...
  13. ncbi Reaching for the bottle of pesticide--a cry for help. Self-inflicted poisonings in Sri Lanka
    Flemming Konradsen
    University of Copenhagen, Copenhagen, Denmark
    Soc Sci Med 62:1710-9. 2006
    ..Using or threatening to use pesticides for self-harm has become a response to stressful events and a powerful message towards a specific individual, or ..
  14. pmc Crop pollination exposes honey bees to pesticides which alters their susceptibility to the gut pathogen Nosema ceranae
    Jeffery S Pettis
    Bee Research Laboratory, USDA ARS, Beltsville, Maryland, United States of America
    PLoS ONE 8:e70182. 2013
    ..Such findings are of great concern given the large numbers and high levels of pesticides found in honey bee colonies...
  15. pmc Cholinergic pesticides cause mushroom body neuronal inactivation in honeybees
    Mary J Palmer
    Division of Neuroscience, Medical Research Institute, Ninewells Medical School, University of Dundee, Dundee, UK
    Nat Commun 4:1634. 2013
    b>Pesticides that target cholinergic neurotransmission are highly effective, but their use has been implicated in insect pollinator population decline...
  16. pmc Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit
    Jennifer A Rusiecki
    Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Environ Health Perspect 116:1547-52. 2008
    ..DNA methylation, an epigenetic mechanism, has been associated with cancer initiation and progression. Greenlandic Inuit have some of the highest reported POP levels worldwide...
  17. ncbi Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review
    Somayyeh Karami-Mohajeri
    Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Hum Exp Toxicol 30:1119-40. 2011
    b>Pesticides, including organophosphate (OP), organochlorine (OC), and carbamate (CB) compounds, are widely used in agricultural and indoor purposes...
  18. ncbi Monitoring and reducing exposure of infants to pollutants in house dust
    John W Roberts
    US Environmental Protection Agency, Reston, VA 22091, USA
    Rev Environ Contam Toxicol 201:1-39. 2009
    ..is the main exposure source for infants to allergens, lead, and PBDEs, as well as a major source of exposure to pesticides, PAHs, Gram-negative bacteria, arsenic, cadmium, chromium, phthalates, phenols, and other EDCs, mutagens, and ..
  19. pmc Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS study
    Amy R Marks
    Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, Berkeley, California 94720, USA
    Environ Health Perspect 118:1768-74. 2010
    Exposure to organophosphate (OP) pesticides, well-known neurotoxicants, has been associated with neurobehavioral deficits in children.
  20. pmc Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides
    Maryse F Bouchard
    Department of Environmental Health, School of Public Health, Harvard University, Boston, MA, USA
    Pediatrics 125:e1270-7. 2010
    ..The goal was to examine the association between urinary concentrations of dialkyl phosphate metabolites of organophosphates and attention-deficit/hyperactivity disorder (ADHD) in children 8 to 15 years of age...
  21. pmc Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley
    Eric M Roberts
    Public Health Institute, Oakland, California 94804, USA
    Environ Health Perspect 115:1482-9. 2007
    Ambient levels of pesticides ("pesticide drift") are detectable at residences near agricultural field sites.
  22. ncbi Mechanisms by which pesticides affect insect immunity
    R R James
    USDA ARS, Pollinating Insects Research Unit, Dept Biology UMC 5310, Utah State University, Logan, UT 84322 5310, USA
    J Invertebr Pathol 109:175-82. 2012
    The current state of knowledge regarding the effect of pesticides on insect immunity is reviewed here...
  23. pmc Exposure to multiple cholinergic pesticides impairs olfactory learning and memory in honeybees
    Sally M Williamson
    Institute of Neuroscience, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK
    J Exp Biol 216:1799-807. 2013
    b>Pesticides are important agricultural tools often used in combination to avoid resistance in target pest species, but there is growing concern that their widespread use contributes to the decline of pollinator populations...
  24. pmc Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy
    Helle R Andersen
    Institute of Public Health, Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark
    Environ Health Perspect 116:566-72. 2008
    ..The aim of this prospective study was to investigate whether occupational pesticide exposure during pregnancy causes adverse effects on the reproductive development in the male infants...
  25. ncbi Pesticides in dust from homes in an agricultural area
    Martha E Harnly
    Environmental Health Investigations Branch, California Department of Public Health, Richmond, California, USA
    Environ Sci Technol 43:8767-74. 2009
    We collected indoor dust samples from homes in the Salinas Valley of California. Of 22 pesticides measured in 504 samples, permethrins and the organophosphate chlorpyrifos were present in highest amounts...
  26. pmc Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children
    Brenda Eskenazi
    Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
    Environ Health Perspect 115:792-8. 2007
    Organophosphate (OP) pesticides are widely used in agriculture and homes. Animal studies suggest that even moderate doses are neurodevelopmental toxicants, but there are few studies in humans.
  27. pmc Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study
    Duk Hee Lee
    Department of Preventative Medicine, Kyungpook National University, Daegu, Korea
    Diabetes Care 34:1778-84. 2011
    ..However, evidence from prospective studies is sparse. This study was performed to evaluate prospective associations of type 2 diabetes with selected POPs among the elderly...
  28. ncbi Comparative sublethal toxicity of nine pesticides on olfactory learning performances of the honeybee Apis mellifera
    A Decourtye
    Association de Coordination Technique Agricole, Maison des Agriculteurs, La Tour de Salvagny, France
    Arch Environ Contam Toxicol 48:242-50. 2005
    ..studies have shown that observations of conditioned PER were of interest for assessing the behavioral effects of pesticides on the honeybee...
  29. ncbi Pest toxicology: the primary mechanisms of pesticide action
    John E Casida
    Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3112, USA
    Chem Res Toxicol 22:609-19. 2009
    b>Pesticides are used to control pests before they harm us or our crops. They are selective toxicants in the form and manner used. Pesticides must be effective without human or crop injury...
  30. ncbi Obesity and persistent organic pollutants: possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls
    Eveline Dirinck
    Department of Endocrinology, Diabetology and Clinical Pharmacology, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium
    Obesity (Silver Spring) 19:709-14. 2011
    ..for the presence of polychlorinated biphenyl (PCB) congeners 153, 138, 180, and 170 and for the organochlorine pesticides, dichloro-diphenyl-dichloroethylene (pp-DDE), and β-hexachlorocyclohexane (βHCH)...
  31. ncbi Bee honey as an environmental bioindicator of pesticides' occurrence in six agricultural areas of Greece
    George Balayiannis
    Laboratory of Chemical Control of Pesticides and Laboratory of Pollution Control of the Environment by Pesticides, Benaki Phytophathological Institute, 151 46, Kifissia, Greece
    Arch Environ Contam Toxicol 55:462-70. 2008
    ..It also shows that, very often, the chemicals used by apiculturists inside the hives in order to control disease are the main pollutants of the produced honey...
  32. pmc Ultrasonic and LIDAR sensors for electronic canopy characterization in vineyards: advances to improve pesticide application methods
    Jordi Llorens
    Department of Agri Food Engineering and Biotechnology, Universitat Politècnica de Catalunya Campus del Baix Llobregat, Edifici D4, Esteve Terradas, 8, 08860 Castelldefels, Spain
    Sensors (Basel) 11:2177-94. 2011
    ..The proposed new technologies seems very appropriate as complementary tools to improve the efficiency of pesticide applications, although further improvements are still needed...
  33. ncbi Using organic-certified rather than synthetic pesticides may not be safer for biological control agents: selectivity and side effects of 14 pesticides on the predator Orius laevigatus
    Antonio Biondi
    University of Catania, Department of Agri Food and Environmental Systems Management, Via Santa Sofia 100, 95123 Catania, Italy
    Chemosphere 87:803-12. 2012
    ..The accurate assessment of the compatibility of various pesticides with predator activity is key for the success of this strategy...
  34. ncbi Gene expression in honey bee (Apis mellifera) larvae exposed to pesticides and Varroa mites (Varroa destructor)
    Ales Gregorc
    Honey Bee Research and Extension Laboratory, Department of Entomology and Nematology, University of Florida, Natural Area Drive, Gainesville, FL 32611, USA
    J Insect Physiol 58:1042-9. 2012
    Honey bee (Apis mellifera) larvae reared in vitro were exposed to one of nine pesticides and/or were challenged with the parasitic mite, Varroa destructor...
  35. ncbi Indirect effects of contaminants in aquatic ecosystems
    John W Fleeger
    Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA
    Sci Total Environ 317:207-33. 2003
    Contaminants such as petroleum hydrocarbons, heavy metals and pesticides can cause direct toxic effects when released into aquatic environments...
  36. pmc Organophosphate pesticide metabolite levels in pre-school children in an agricultural community: within- and between-child variability in a longitudinal study
    W Griffith
    Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA 98195 7234, USA
    Environ Res 111:751-6. 2011
    ..The goal of this analysis was to investigate these variability components during periods when organophosphate pesticides were and were not actively applied to orchards in that community...
  37. ncbi Population-level effects of pesticides and other toxicants on arthropods
    John D Stark
    Department of Entomology, Washington State University, 7612 Pioneer Way East, Puyallup, Washington 98371, USA
    Annu Rev Entomol 48:505-19. 2003
    New developments in ecotoxicology are changing the way pesticides and other toxicants are evaluated...
  38. pmc Effect of endocrine disruptor pesticides: a review
    Wissem Mnif
    Laboratoire de Biochimie, Unité de Recherche 02 UR 09 01, Institut Superieur de Biotechnologie, de Monastir, BP 74, 5019 Monastir, Tunisia
    Int J Environ Res Public Health 8:2265-303. 2011
    ..A huge number of chemicals have been identified as endocrine disruptors, among them several pesticides. Pesticides are used to kill unwanted organisms in crops, public areas, homes and gardens, and parasites in ..
  39. pmc Does the clock make the poison? Circadian variation in response to pesticides
    Louisa A Hooven
    Department of Zoology, Oregon State University, Corvallis, Oregon, United States of America
    PLoS ONE 4:e6469. 2009
    ..To determine whether reported XM gene expression rhythms result in functional rhythms, we examined daily profiles of enzyme activity and dose responses to the pesticides propoxur, deltamethrin, fipronil, and malathion.
  40. ncbi Significance of urban and agricultural land use for biocide and pesticide dynamics in surface waters
    I K Wittmer
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Water Res 44:2850-62. 2010
    Biocides and pesticides are designed to control the occurrence of unwanted organisms. From their point of application, these substances can be mobilized and transported to surface waters posing a threat to the aquatic environment...
  41. ncbi American Healthy Homes Survey: a national study of residential pesticides measured from floor wipes
    Daniel M Stout
    National Exposure Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    Environ Sci Technol 43:4294-300. 2009
    ..22 ng/cm2 and GM 0.14 ng/ cm2) and cypermethrin (mean 2.9 ng/cm2 and GM 0.03 ng/ cm2). Results show that most floors in occupied homes in the U.S. have measurable levels of insecticides that may serve as sources of exposure to occupants...
  42. ncbi Subchronic exposure of honeybees to sublethal doses of pesticides: effects on behavior
    Yassine Aliouane
    Centre de Recherches sur la Cognition Animale UMR CNRS 5169, Universite Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex, France
    Environ Toxicol Chem 28:113-22. 2009
    ..Our data on the intrinsic toxicity of the compounds after chronic exposure have to be taken into account for evaluation of risk to honeybees in field conditions...
  43. pmc Association of pesticide exposure with neurologic dysfunction and disease
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 112:950-8. 2004
    Poisoning by acute high-level exposure to certain pesticides has well-known neurotoxic effects, but whether chronic exposure to moderate levels of pesticides is also neurotoxic is more controversial...
  44. pmc Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans
    Keon Yeop Kim
    Department of Preventative Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
    Environ Health Perspect 118:370-4. 2010
    ..Whether these associations extend to a population with much lower concentrations of POPs is not known...
  45. ncbi Plantation work and risk of Parkinson disease in a population-based longitudinal study
    Helen Petrovitch
    Department of Medicine, University of Hawaii John A Burns School of Medicine, USA
    Arch Neurol 59:1787-92. 2002
    Parkinson disease (PD) has an unknown cause; however, convincing evidence is emerging that indicates pesticides can selectively injure the dopaminergic system in laboratory animals...
  46. pmc Pesticides and Parkinson's disease--is there a link?
    Terry P Brown
    Medical Research Council Institute for Environment and Health, University of Leicester, Leicester, United Kingdom
    Environ Health Perspect 114:156-64. 2006
    ..It has been postulated that exogenous toxicants, including pesticides, might be involved in the etiology of PD...
  47. pmc Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California
    Sadie Costello
    Department of Environmental Health Sciences, University of California, Berkeley, 94720 7360, USA
    Am J Epidemiol 169:919-26. 2009
    Evidence from animal and cell models suggests that pesticides cause a neurodegenerative process leading to Parkinson's disease (PD)...
  48. ncbi Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea
    H K Son
    Department of Preventive Medicine, Kyungpook National University, Jung Gu, Daegu, South Korea
    Environ Int 36:410-4. 2010
    Low-dose organochlorine (OC) pesticides have recently been associated with type 2 diabetes in several non-Asian general populations...
  49. ncbi Analyzing effects of pesticides on invertebrate communities in streams
    Matthias Liess
    UFZ Centre for Environmental Research, Permoserstrasse 15, D 04318 Leipzig, Germany
    Environ Toxicol Chem 24:954-65. 2005
    ..was to find patterns in aquatic invertebrate community composition that are related to the effects of pesticides. Investigations were carried out in 20 central European streams...
  50. ncbi Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort
    Stephanie M Engel
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Am J Epidemiol 165:1397-404. 2007
    Prenatal exposures to organophosphate pesticides and polychlorinated biphenyls have been associated with abnormal neonatal behavior and/or primitive reflexes...
  51. ncbi Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 157:800-14. 2003
    The authors examined the relation between 45 common agricultural pesticides and prostate cancer incidence in a prospective cohort study of 55,332 male pesticide applicators from Iowa and North Carolina with no prior history of prostate ..
  52. ncbi Associations of pesticides, HCV, HBV, and hepatocellular carcinoma in Egypt
    Sameera Ezzat
    National Liver Institute, Menoufiya University, Shibin El Kom, Egypt
    Int J Hyg Environ Health 208:329-39. 2005
    ..A major segment of the population is employed in agriculture, raising the possibility that exposure to pesticides is an additional risk factor for HCC...
  53. ncbi Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada
    Aziz Aris
    Department of Obstetrics and Gynecology, University of Sherbrooke Hospital Centre, Sherbrooke, Quebec, Canada
    Reprod Toxicol 31:528-33. 2011
    b>Pesticides associated to genetically modified foods (PAGMF), are engineered to tolerate herbicides such as glyphosate (GLYP) and gluphosinate (GLUF) or insecticides such as the bacterial toxin bacillus thuringiensis (Bt)...
  54. ncbi Can pesticides and larval competition alter susceptibility of Aedes mosquitoes (Diptera: Culicidae) to arbovirus infection?
    Ephantus J Muturi
    Illinois Natural History Survey, University of Illinois, 1816 S Oak Street, Champaign, IL 61820, USA
    J Med Entomol 48:429-36. 2011
    ..The application of pesticides used for control may alter these density-dependent interactions with consequences for the number of survivors ..
  55. ncbi Effects of pesticides on human peripheral lymphocytes in vitro: induction of DNA damage
    U Undeger
    Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey
    Arch Toxicol 79:169-76. 2005
    Because of the widespread use of pesticides for domestic and industrial applications the evaluation of their genotoxic effects is of major concern to public health...
  56. ncbi Impacts of climate change on the fate and behaviour of pesticides in surface and groundwater--A UK perspective
    J P Bloomfield
    Maclean Building, British Geological Survey, Crowmarsh Gifford, Wallingford, Oxfordshire, OX10 8BB, UK
    Sci Total Environ 369:163-77. 2006
    Over the last two decades significant effort has been dedicated to understanding the fate and transport of pesticides in surface water and groundwater and to use this understanding in the development of environmental policy and regulation...
  57. ncbi Pesticide exposure as a risk factor for amyotrophic lateral sclerosis: a meta-analysis of epidemiological studies: pesticide exposure as a risk factor for ALS
    Angela M Malek
    Department of Neurosciences, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    Environ Res 117:112-9. 2012
    Exposure to pesticides and agricultural chemicals has been linked to amyotrophic lateral sclerosis (ALS) although findings have been inconsistent...
  58. ncbi Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: correlation of UV filters with use of cosmetics
    Margret Schlumpf
    GREEN Tox and Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Chemosphere 81:1171-83. 2010
    ..e., organochlor pesticides and metabolites, polybrominated diphenylethers and polychlorinated biphenyls (PCBs)...
  59. pmc Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides
    Sarah Jane Mackenzie Ross
    Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Neurotoxicol Teratol 32:452-9. 2010
    The study aim was to determine whether low level exposure to organophosphate pesticides (OPs) causes neuropsychological or psychiatric impairment...
  60. pmc Pesticides, chromosomal aberrations, and non-Hodgkin's lymphoma
    Brian C H Chiu
    Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 4402, USA
    J Agromedicine 14:250-5. 2009
    ..of non-Hodgkin's lymphoma (NHL) has been reported among farmers and other occupational groups working with pesticides. Some pesticides exhibit immunotoxic and genotoxic activities...
  61. ncbi A gene-environment study of the paraoxonase 1 gene and pesticides in amyotrophic lateral sclerosis
    Julia M Morahan
    The Stacey MND Laboratory, Department of Pathology, The University of Sydney, Sydney, NSW 2006, Australia
    Neurotoxicology 28:532-40. 2007
    ..SALS has been associated with exposure to environmental toxins, including pesticides and chemical warfare agents, many of which are organophosphates...
  62. ncbi The risk of adverse reproductive and developmental disorders due to occupational pesticide exposure: an overview of current epidemiological evidence
    Wojciech Hanke
    Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
    Int J Occup Med Environ Health 17:223-43. 2004
    ..In general, no effect of exposure to pesticides on sexual hormones was observed...
  63. ncbi High rates of suicide and attempted suicide using pesticides in Nickerie, Suriname, South America
    T Graafsma
    Department of Medical Psychology, General Hospital in Nickerie, Suriname
    Crisis 27:77-81. 2006
    ..Particularly remarkable is the high number of attempted suicides among males (49%), and the use of pesticides in both fatal (55%) and nonfatal suicidal behavior (44%)...
  64. pmc Entomopathogenic fungus as a biological control for an important vector of livestock disease: the Culicoides biting midge
    Minshad Ali Ansari
    Pure and Applied Ecology, Swansea University, Swansea, United Kingdom
    PLoS ONE 6:e16108. 2011
    ..nubeculosus in laboratory and greenhouse studies...
  65. pmc Associations of prenatal exposure to organophosphate pesticide metabolites with gestational age and birth weight
    Stephen A Rauch
    Child and Family Research Institute, BC Children s Hospital, Vancouver, British Columbia, Canada
    Environ Health Perspect 120:1055-60. 2012
    Prenatal exposure to organophosphate (OP) insecticides, a widely used class of pesticides, may be associated with decreased gestational age and lower birth weight...
  66. ncbi Effects of model organophosphorous pesticides on DNA damage and proliferation of HepG2 cells
    Irena Hreljac
    Department for Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia
    Environ Mol Mutagen 49:360-7. 2008
    Organophosphorous compounds (OPs) are commonly used pesticides. The primary mechanism of OP toxicity is the inhibition of acetylcholine esterase in the nervous system leading to a variety of acute and chronic effects...
  67. ncbi Patterns of pesticide use in California and the implications for strategies for reduction of pesticides
    Lynn Epstein
    Department of Plant Pathology, University of California, Davis, California 95616 8680, USA
    Annu Rev Phytopathol 41:351-75. 2003
    ....
  68. ncbi Determination of chlorinated pesticides, polychlorinated biphenyls, and polybrominated diphenyl ethers in human milk from Bizerte (Tunisia) in 2010
    Sihem Ben Hassine
    Laboratory of Environmental Analytical Chemistry 05 UR 12 03, University of Carthage, 7021 Zarzouna, Tunisia
    Chemosphere 89:369-77. 2012
    Thirty persistent organohalogen compounds including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs) were determined in breast milk samples (n=36) of primipara and multipara ..
  69. pmc Tipping the balance of autism risk: potential mechanisms linking pesticides and autism
    Janie F Shelton
    Graduate Group in Epidemiology, Department of Public Health Science, University of California, Davis, Davis, California 95616, USA
    Environ Health Perspect 120:944-51. 2012
    ..replicated findings have yet to appear on any specific exposure; however, mounting evidence suggests gestational pesticides exposures are strong candidates...
  70. pmc Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study
    Christine Wohlfahrt-Veje
    University Dept, of Growth and Reproduction, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    Environ Health 10:79. 2011
    ..Long-term effects of prenatal exposure to non-persistent pesticides on body composition have so far not been investigated...
  71. pmc Variability of organophosphorous pesticide metabolite levels in spot and 24-hr urine samples collected from young children during 1 week
    Asa Bradman
    Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, Berkeley, California 94704, USA
    Environ Health Perspect 121:118-24. 2013
    ..in spot urine samples are frequently used to characterize children's exposures to organophosphorous (OP) pesticides. However, variable exposure and short biological half-lives of OP pesticides could result in highly variable ..
  72. ncbi Exposure to pesticides as risk factor for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies
    Lennart Hardell
    Department of Oncology, Orebro University Hospital, Sweden
    Leuk Lymphoma 43:1043-9. 2002
    Increased risk for non-Hodgkin's lymphoma (NHL) following exposure to certain pesticides has previously been reported...
  73. ncbi Biological monitoring of exposure to pesticides: current issues
    F He
    Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing, P R China
    Toxicol Lett 108:277-83. 1999
    ..Selection of suitable biomarkers of exposure to pesticides, development of detection methods, validation of measurement and interpretation of results are of utmost concern ..
  74. ncbi Degradation of contrasting pesticides by white rot fungi and its relationship with ligninolytic potential
    Gary D Bending
    Horticulture Research International, Wellesbourne, Warwick CV35 9EF, UK
    FEMS Microbiol Lett 212:59-63. 2002
    ..of nine species of white rot fungus from a variety of basidiomycete orders to degrade contrasting mono-aromatic pesticides was investigated...
  75. pmc Use of a terrestrial LIDAR sensor for drift detection in vineyard spraying
    Emilio Gil
    Department of Agri Food Engineering and Biotechnology, Universitat Politecnica de Catalunya, Barcelona, Spain
    Sensors (Basel) 13:516-34. 2013
    ..In general; the use of the LIDAR sensor presents an interesting and easy technique to establish the potential drift of a specific spray situation as an adequate alternative for the evaluation of drift potential...
  76. ncbi Ecological models in support of regulatory risk assessments of pesticides: developing a strategy for the future
    Valery E Forbes
    Centre for Integrated Population Ecology, Department of Environmental, Social and Spatial Change, Roskilde University, Roskilde, Denmark
    Integr Environ Assess Manag 5:167-72. 2009
    ..Europe, the United States, and Asia, to discuss the role of ecological modeling in risk assessments of pesticides, particularly under the European regulatory framework...
  77. ncbi Occupational exposure of farm workers to pesticides: biochemical parameters and evaluation of genotoxicity
    Aline Pértile Remor
    Departamento de Ciências da Saúde, Universidade Regional Integrada do Alto Uruguai e das Missões URI, Erechim, RS, Brazil
    Environ Int 35:273-8. 2009
    To assess the effects of exposure to complex mixtures of pesticides in farm workers from two communities from Rio Grande do Sul, Brazil, we evaluated the activities of butyrylcholinesterase (BChE) and delta-aminolevulinic acid dehydratase ..
  78. pmc The implications of using a physiologically based pharmacokinetic (PBPK) model for pesticide risk assessment
    Chensheng Lu
    Exposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 118:125-30. 2010
    ....
  79. pmc Exposure to multiple pesticides and risk of non-Hodgkin lymphoma in men from six Canadian provinces
    Karin Hohenadel
    Occupational Cancer Research Centre, 505 University Avenue, 14th Floor, Toronto, Ontario M5G 1X3, Canada
    Int J Environ Res Public Health 8:2320-30. 2011
    Non-Hodgkin lymphoma (NHL) has been linked to several agricultural exposures, including some commonly used pesticides. Although there is a significant body of literature examining the effects of exposure to individual pesticides on NHL, ..
  80. ncbi Broken sperm, cytoplasmic droplets and reduced sperm motility are principal markers of decreased sperm quality due to organophosphorus pesticides in rats
    Ai Okamura
    Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Aichi 467 8601, Japan
    J Occup Health 51:478-87. 2009
    ..The aim of this study was to clarify the effects of OP exposure on detailed sperm toxicity markers, i.e., motility, morphology and sperm adenine nucleotide contents, and the histopathology of the testis and epididymis...
  81. ncbi Potential of 11 pesticides to initiate downstream drift of stream macroinvertebrates
    Mikhail A Beketov
    Dept System Ecotoxicology, UFZ Helmholtz Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany
    Arch Environ Contam Toxicol 55:247-53. 2008
    ..The aim of the present study was to evaluate potential drift-initiating action of 11 pesticides having different target groups and modes of action...
  82. ncbi The use of developmental neurotoxicity data in pesticide risk assessments
    Kathleen C Raffaele
    Office of Research and Development, U S Environmental Protection Agency, 1200 Pennsylvania Ave, Washington, DC 20460, USA
    Neurotoxicol Teratol 32:563-72. 2010
    ..of the Food Quality Protection Act, which mandated an increased focus on evaluating the potential toxicity of pesticides to children, the number of guideline developmental neurotoxicity (DNT) studies (OPPTS 870...
  83. ncbi Effects of pesticides on community composition and activity of sediment microbes--responses at various levels of microbial community organization
    Anneli Widenfalk
    Department of Environmental Assessment, Swedish University of Agricultural Sciences, P O Box 7050, SE 750 07 Uppsala, Sweden
    Environ Pollut 152:576-84. 2008
    A freshwater sediment was exposed to the pesticides captan, glyphosate, isoproturon, and pirimicarb at environmentally relevant and high concentrations...
  84. pmc Pesticides and atopic and nonatopic asthma among farm women in the Agricultural Health Study
    Jane A Hoppin
    NIEHS Epidemiology Branch, MD A3 05, P O Box 12233, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 177:11-8. 2008
    ..Risk factors for asthma among farm women are understudied...
  85. ncbi CYP 1A1 polymorphism and organochlorine pesticides levels in the etiology of prostate cancer
    Vivek Kumar
    Environmental Biochemistry and Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences and GTB Hospital, University of Delhi, Dilshad Garden, Delhi 110 095, India
    Chemosphere 81:464-8. 2010
    Organochlorine pesticides (OCPs) and polymorphisms of xenobiotic metabolizing enzymes are reported to be associated with the possible risk of prostate cancer...
  86. ncbi Environmental context determines community sensitivity of freshwater zooplankton to a pesticide
    Nathalie C Stampfli
    Department of System Ecotoxicology, Helmholtz Centre for Environmental Research UFZ, Permoserstraße 15, 04318 Leipzig, Germany
    Aquat Toxicol 104:116-24. 2011
    ..These findings indicate that environmental context is more important for ecotoxicological evaluation than assumed previously...
  87. ncbi Impact of pesticides used in agriculture and vineyards to surface and groundwater quality (North Spain)
    Alain Hildebrandt
    Department of Environmental Chemistry, IIQAB Consejo Superior de Investigaciones Cientificas, Jordi Girona 18 26, Barcelona, Catalonia, Spain
    Water Res 42:3315-26. 2008
    An environmental monitoring program was carried out to determine the impact of eight pesticides on the surface and groundwater quality of agricultural areas within the Ebro, Duero and Miño river basins...
  88. pmc Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California
    Myles Cockburn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Am J Epidemiol 173:1280-8. 2011
    ..Past ambient exposures to pesticides/fungicides were derived from residential history and independently recorded pesticide and land-use data, using a ..
  89. ncbi China: forward to the green pesticides via a basic research program
    Xuhong Qian
    Shanghai Key Laboratory of Chemical Biology, Institute of Pharmaceuticals and Pesticides, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
    J Agric Food Chem 58:2613-23. 2010
    ..1, stage 2 (2010-2014) of this program will focus on the molecular target-oriented innovation of green chemical pesticides. This commentary presents key learnings and accomplishments from the stage 1 of China's green chemical pesticide ..
  90. ncbi Pyrethroid and organophosphorus pesticides in composite diet samples from Atlanta, USA adults
    Anne M Riederer
    Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, Georgia 30322, USA
    Environ Sci Technol 44:483-90. 2010
    ..permethrin, cyfluthrin, cypermethrin, deltamethrin) and 3 organophosphorus (chlorpyrifos, diazinon, malathion) pesticides were measured in 4 days of 24 h duplicate diet samples collected from 12 Atlanta adults over two cycles (2005-..
  91. pmc Access to farming pesticides and risk for suicide in Chinese rural young people
    Yuanyuan Kong
    Department of Epidemiology and Statistics, School of Public Health, Shandong University, Jinan, Shandong 250012, China
    Psychiatry Res 179:217-21. 2010
    Suicide is a leading cause of death in individuals 15-34 years of age in China. Highly lethal pesticides are a common method used for suicide in Chinese rural areas...
  92. ncbi Ecological models and pesticide risk assessment: current modeling practice
    Amelie Schmolke
    UFZ, Helmholtz Centre for Environmental Research, Department of Ecological Modelling, Permoserstrasse 15, 04318 Leipzig, Germany
    Environ Toxicol Chem 29:1006-12. 2010
    Ecological risk assessments of pesticides usually focus on risk at the level of individuals, and are carried out by comparing exposure and toxicological endpoints...
  93. pmc Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women
    Kim G Harley
    Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, California, United States of America
    PLoS ONE 6:e23923. 2011
    ..We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this association...
  94. ncbi Prenatal pesticide and PCB exposures and birth outcomes
    Mary S Wolff
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Pediatr Res 61:243-50. 2007
    ..polychlorinated biphenyls (PCBs), 1,1'-dichloro-2,2'-bis(4-chlorophenyl)ethylene (DDE), and organophosphate (OP) pesticides and adverse pregnancy outcomes, although they are known developmental toxicants...
  95. pmc Occupational exposure to pesticides increases the risk of incident AD: the Cache County study
    K M Hayden
    Duke University Medical Center, Durham, NC, USA
    Neurology 74:1524-30. 2010
    Commonly used organophosphate and organochlorine pesticides inhibit acetylcholinesterase at synapses in the somatic, autonomic, and central nervous systems and may therefore have lasting effects on the nervous system...
  96. ncbi Amphibians and agricultural chemicals: review of the risks in a complex environment
    Reinier M Mann
    Centre for Ecotoxicology, Department of Environmental Sciences, University of Technology Sydney, NSW, Australia
    Environ Pollut 157:2903-27. 2009
    ..the persistence and health of amphibian populations are likely to be compromised by the escalating use of pesticides and other agricultural chemicals...
  97. ncbi Development of a framework based on an ecosystem services approach for deriving specific protection goals for environmental risk assessment of pesticides
    Karin M Nienstedt
    European Food Safety Authority, Largo N Palli 5 A, 43121 Parma, Italy
    Sci Total Environ 415:31-8. 2012
    ..EFSA) as well as examples of resulting SPGs obtained so far for environmental risk assessment (ERA) of pesticides is presented...
  98. pmc Associations of serum concentrations of organochlorine pesticides with breast cancer and prostate cancer in U.S. adults
    Xiaohui Xu
    Department of Epidemiology and Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA
    Environ Health Perspect 118:60-6. 2010
    Organochlorine (OC) pesticides are a group of environmental endocrine disruptors that may be associated with an increased risk for hormone-related cancers including cancers of the breast and prostate...
  99. ncbi Exposure to pesticides and risk of childhood cancer: a meta-analysis of recent epidemiological studies
    Florence Vinson
    INRA, UMR1089 Xenobiotiques, 180 chemin de Tournefeuille, BP93173, F 31027 Toulouse cedex 3, France
    Occup Environ Med 68:694-702. 2011
    The authors performed a meta-analysis of case-control and cohort studies to clarify the possible relationship between exposure to pesticides and childhood cancers.
  100. ncbi Pesticides and their metabolites in the homes and urine of farmworker children living in the Salinas Valley, CA
    Asa Bradman
    Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
    J Expo Sci Environ Epidemiol 17:331-49. 2007
    ..We measured 29 common agricultural and home use pesticides in multiple exposure media samples...
  101. pmc Assessment of a pesticide exposure intensity algorithm in the agricultural health study
    Kent W Thomas
    US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA
    J Expo Sci Environ Epidemiol 20:559-69. 2010
    ..cohort study of pesticide applicators who provided detailed questionnaire information on their use of specific pesticides. A field study was conducted for a subset of the applicators enrolled in the AHS to assess a pesticide exposure ..

Research Grants77

  1. ORGANOPHOSPHATE PESTICIDES AND HUMAN REPRODUCTIVE HEALTH
    Xiping Xu; Fiscal Year: 2003
    ..follow a cohort of women and their husbands to assess the effects of exposure to organophosphate (OP) pesticides on adverse reproductive outcomes in both men and women in agricultural workers...
  2. Prenatal Exposures & Procarcinogenic Mutations
    Manuela Orjuela; Fiscal Year: 2007
    ..varying levels of environmental exposures including polycyclic aromatic hydrocarbons (PAH) and organophosphate pesticides such as chlorpyrifos. Prenatal exposures have been assessed by questionnaires, air monitoring, and biomarkers...
  3. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2011
    ..mission, agencies need to determine whether adverse effects might result from exposures to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, ..
  4. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2012
    ..mission, agencies need to determine whether adverse effects might result from exposures to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, ..
  5. NIEHS SUPPORT OF THE AHS COHORT STUDY AT NCI
    Charles Knott; Fiscal Year: 2010
    The Agricultural Health Study (AHS) is a major effort which is designed to evaluate the relationship between pesticides and other agricultural factors and the risk of cancer and other diseases...
  6. THE AGRICULTURAL HEALTH STUDY - FIELD STATIONS
    Charles Lynch; Fiscal Year: 2010
    The Agricultural Health Study (AHS) is a major effort which is designed to evaluate the relationship between pesticides and other agricultural factors and the risk of cancer and other diseases...
  7. Multi-targeted Countermeasures against Acute and Delayed Effects of OP Exposure
    John A Butera; Fiscal Year: 2013
    ..The classic OP nerve agents such as sarin, soman, tabun, and VX, along with related OP pesticides represent some of the most toxic materials known to humankind...
  8. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2009
    ..mission, agencies need to determine whether adverse effects might result from exposures to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, ..
  9. Dietary Lipids and Silica-Accelerated Autoimmunity
    James J Pestka; Fiscal Year: 2013
    ..risk of autoimmunity from exposures to toxicants such as asbestos, heavy metals, trichloroethylene, and pesticides. Finally, it is expected that these studies will reveal additional potential benefits of n-3 PUFA consumption on ..
  10. Novel Zebrafish Models to Study Toxicity of PCBs and Pesticides During Pregnancy
    Lisa Satterwhite; Fiscal Year: 2009
    ..Strikingly, the PCB- induced HLH and pesticide associated birth defects may be related because PCBs and some pesticides disrupt cells by the same mechanism: activation of the aryl hydrocarbon receptor (AHR) signaling pathway which ..
  11. GI Endotoxin as an Environmental Trigger in an alpha-Synuclein Transgenic Mouse
    Robert L Nussbaum; Fiscal Year: 2012
    ..viral infection, heavy metals, bacterial toxins, microbe-induced inflammation, and chemical agents including pesticides. The balance between genetic predisposition and environmental insult is likely to be different depending on the ..
  12. Vascular and Skeletal Muscle Function in Gulf War Veterans Illness
    Scott Kinlay; Fiscal Year: 2013
    ..Symptoms and exposure to pesticides, pyridostigmine bromide, and low level sarin exposure are well documented in these cohorts...
  13. NATIONAL CHILDREN'S STUDY - CACHE COUNTY STUDY CENTER
    Edward Clark; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  14. Oxidative stress and neurogenetic networks in Drosophila
    Robert R H Anholt; Fiscal Year: 2010
    ..standing challenge in environmental health science is to assess the effects of environmental chemicals such as pesticides or herbicides on genetic risk for neurodegenerative diseases as manifest through locomotor dysfunction (e.g...
  15. Lipid glyceryl ester homeostasis in macrophages and perturbation by environmental
    Matthew K Ross; Fiscal Year: 2012
    ..b>Pesticides, such as organophosphates (OPs), are environmental toxicants that can be detoxified by CES;however, CES are ..
  16. Detection of engineered nanomaterials in drinking water, food, commercial product
    Paul K Westerhoff; Fiscal Year: 2010
    ..is rapidly resulting in the production of nanomaterials (NMs) that will be used in everything from toothpaste to pesticides, yet the research community lacks adequate techniques to measure the size and concentration of nanomaterials in ..
  17. DNA methylation alterations in response to pesticides exposure
    Lifang Hou; Fiscal Year: 2010
    ..In the US, exposure to pesticides is ubiquitous, and over one million people are subjected to high occupational exposure...
  18. The role of human DNA polymerase eta in the mutagenic response to oxidative stres
    SCOTT DAVID MCCULLOCH; Fiscal Year: 2013
    ..caused by a number of environmental agents such as polycyclic aromatic hydrocarbons like dioxin, heavy metals, pesticides, and ultraviolet and ionizing radiation...
  19. Epidemiological Research on Autism in Jamaica - Phase II
    Mohammad H Rahbar; Fiscal Year: 2013
    ..In the proposed project, we will assess the levels of polychlorinated biphenyls (PCBs) and organochlorine (OC) pesticides in the cord-blood isolated from 144 newborns enrolled in the 2011 Jamaican birth cohort to test the hypothesis ..
  20. Paternal Environmental Exposures and Reproductive Outcomes: A Comparison of in Vi
    DEBORAH ANN HANSEN; Fiscal Year: 2013
    ..and biochemical abnormalities have been reported in F1 and F2 generations following paternal exposures to pesticides, herbicides, and radiation...
  21. Memory and Mood Enhancing Therapies for Gulf War Illness
    Ashok K Shetty; Fiscal Year: 2013
    ..Intake of the prophylactic drug pyridostigmine bromide (PB), prolonged exposure to pesticides (such as DEET and permethrin), and the combat-related stress during the Persian Gulf War-1 are believed to be ..
  22. NATIONAL CHILDREN'S STUDY -CLINICAL BIOLOGICAL ANALYSIS
    VELAZQUEZ FRANCISCO; Fiscal Year: 2011
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  23. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  24. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  25. NATIONAL CHILDREN'S STUDY SUPPORT
    Betty Wood; Fiscal Year: 2011
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  26. Environmental Endocrine Disruptors and Human Sperm Chromosomal Abnormalities
    Melissa Perry; Fiscal Year: 2012
    ..from our group has found associations between organochlorines and inferior semen quality and contemporary use pesticides and DNA damage. The question remains as to whether these exposures impact sperm aneuploidy...
  27. NATIONAL CHILDREN'S STUDY COORDINATING CENTER
    Elaine D Eaker; Fiscal Year: 2009
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to a ..
  28. System for Decontaminating Well Water for Drinking
    GIRISH SRINIVAS; Fiscal Year: 2010
    ..g. lead), organic contaminants (e.g. pesticides), as well as trace amounts of hazardous materials such as arsenic, perchlorate, nitrates and nitrites...
  29. International Training and Research in Environmental and Occupational Health
    NELSON K STEENLAND; Fiscal Year: 2012
    ..pesticide applicators in the Majes valley of Peru do not use protective equipments when using organophosphate pesticides. Two other Peruvian Fogarty studies funded via Emory showed a similar situation with informal gold miners using ..
  30. Design of a high-throughput screen for chemicals that cause meiotic aneuploidy
    Patrick Allard; Fiscal Year: 2011
    ..contribution in the etiology of meiotic chromosome segregation errors as compounds as diverse as plastics, pesticides and anti-anxiety drugs have been shown to cause meiotic aneuploidies in mammals...
  31. NATIONAL CHILDREN'S STUDY
    William Hogan; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  32. SUPPORT OF THE NATIONAL CHILDREN'S STUDY INFORMATION SYSTEM
    JAMES TER MAAT; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  33. NATIONAL CHILDREN'S STUDY
    Helen Koo; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  34. NATIONAL CHILDREN'S STUDY
    Kristina Lewis; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  35. NATIONAL CHILDREN'S STUDY SUPPORT
    Russell Walker; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  36. NATIONAL CHILDREN'S STUDY BIOMEDICAL (APPLIED/EXPLORATORY)
    Lee Smith; Fiscal Year: 2011
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  37. PHAHs and Thyroid Cancer Risk in DoDSR Cohort
    Yawei Zhang; Fiscal Year: 2013
    ..polyhalogenated aromatic hydrocarbons (PHAHs), including polychlorinated biphenyls (PCBs) and organochlorine pesticides, are able to alter thyroid hormone homeostasis and cause thyroid dysfunction...
  38. NATIONAL CHILDREN'S STUDY BIOMEDICAL (APPLIED/EXPLORATORY)
    Lee Smith; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  39. NATIONAL CHILDREN'S STUDY
    Helen Koo; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  40. NATIONAL CHILDREN'S STUDY
    DANA DABALEA; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  41. Training in Environmental Health to Reduce Chronic Disease in Latin America
    Philip J Landrigan; Fiscal Year: 2013
    ..3) exposure to lead and other heavy metals and neurotoxins such as pesticides continue in the developing world and contribute to neurobehavioral effects later in life...
  42. Indicators of early neurodegeneration: gene-toxin interactions at the syanpse
    Felix E Schweizer; Fiscal Year: 2010
    ..We find that environmental toxins such as pesticides that are implicated in Parkinson's disease (PD) rapidly affect synaptic transmission and synaptic ..
  43. Next Generation Oxime Therapeutic for Chemical Agent Inhibited CNS (Brain) ChEs
    Richard K Gordon; Fiscal Year: 2010
    ..b>Pesticides and OPs are significant terrorist threats to civilian populations...
  44. Perinatal Exposure to Environmental DDT and Risk of Metabolic Syndrome
    Michele La Merrill; Fiscal Year: 2012
    ..There are however, human and mechanistic laboratory data suggesting that organochlorine pesticides, DDT among them, are associated with increased risk of diabetes and the metabolic syndrome...
  45. Neurotoxicity of organophosphorus pesticides in developing guinea pigs
    William Randall; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Organophosphorus (OP) pesticides are among the most heavily used pest control agents worldwide...
  46. Strategies for Heavy Metal Detoxification
    Gerard Parkin; Fiscal Year: 2013
    ..Furthermore, the use of organomercurials as pesticides resulted in the death of ca 500 people in Iraq in the early 1970s when wheat seeds treated with these pesticides ..
  47. Endocrine Disruptors: Assessment of endocrine disruption activity, mechanism and
    Subhrangsu Mandal; Fiscal Year: 2010
    ..Sources of EDCs may include daily foods, drinking water, plastics, pesticides, synthetic hormones etc...
  48. Transcriptomics and Population Genetics of Mosquito Resistance to Pyrethroids
    Mariangela Bonizzoni; Fiscal Year: 2013
    ..The same classes of insecticide used in vector control strategies also are used as pesticides for agricultural purposes...
  49. Environmental PPAR Agonists Accelerate Aging of Bone and Impair Lymphopoiesis
    AMELIA RACHEL HAAS BAKER; Fiscal Year: 2013
    ..concern in the marine environment due to its use as an anti-fouling agent;however the use of TBT in agricultural pesticides, wood preservatives and the manufacturing of plastics has resulted in significant land-based sources of this ..
  50. NATIONAL CHILDREN'S STUDY - PROGRAM &PLANNING SUPPORT FOR THE NCS PROGRAM OFFICE
    RAJNI SAMAVEDAM; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  51. NATIONAL CHILDREN'S STUDY - PROGRAM &PLANNING SUPPORT FOR THE NCS PROGRAM OFFICE
    RAJNI SAMAVEDAM; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  52. NATIONAL CHILDREN'S STUDY - SCHUYLKILL COUNTY STUDY CENTER
    Jennifer Culhane; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  53. Impact of maternal work in the Ecuadorian flower industry on infant development
    Alexis Handal; Fiscal Year: 2011
    ..This study will further our understanding of exposure to non-persistent, acutely toxic pesticides, which have become the most commonly used pesticides in agricultural industry in the Unites States and globally...
  54. LOGISTICS FOR NATIONAL CHILDREN'S STUDY
    David J Tollerud; Fiscal Year: 2009
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  55. HEME PROTEIN REDUCTASES
    Stephen G Sligar; Fiscal Year: 2012
    ..including cholesterol and steroid structures, long chain alkanes, aromatics, fatty acids, drugs, insecticides, pesticides, critical signaling molecules and carcinogen precursors...
  56. NATIONAL CHILDREN'S STUDY
    JANUARY HRICISAK; Fiscal Year: 2013
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  57. NATIONAL CHILDREN'S STUDY
    Anthony Mawson; Fiscal Year: 2012
    ..environmental exposures compared to adults;known ongoing exposures, such as prevalent levels of non-persistent pesticides or hours of media exposure per day in young children;and evidence for environmental contributions or causes to ..
  58. Mosquito Vector Control Using Bt Coupled to Seed Oil Bodies
    Mohd Amir Abdullah; Fiscal Year: 2009
    ..BtB and Bti can lead to substantially improved control of disease vectoring mosquito species by biological pesticides, lowering the amount of chemical pesticides entering aquatic environments. The U.S...
  59. Definitive Studies For Use Of Galantamine As A Pre-Treatment Countermeasure Again
    BILL BASINGER; Fiscal Year: 2011
    ..Track SBIR Phase I and Phase II Exposure to centrally acting military nerve agents and organophosphorus (OP) pesticides are known to cause death and neurological damage (Coupland 2005, Karalliedee 1989, Buckley 2004)...
  60. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2007
    ..neurotoxins such as paraoxon, sarin, soman, VX, and Russian-VX, are a broad class of chemicals commonly used as pesticides and chemical warfare (CW) agents...
  61. Mixture Modeling: Pesticide Drug Interactions
    Charles Timchalk; Fiscal Year: 2009
    ..Among pesticides, organophosphorus insecticides like chlorpyrifos have been of particular concern since they are widely utilized, ..
  62. PHYTOESTROGENS, ORGANOCHLORINES, AND FIBROID RISK
    Stephen Schwartz; Fiscal Year: 1999
    Phytoestrogens (such as isoflavones and lignans) and organochlorine compounds (such as pesticides and polychlorinated biphenyls) are two broad classes of putative endocnne disruptors -- chemicals that may have the capability to alter a ..
  63. Data Mining Assisted Discovery of Novel Organophosphorou
    Robert Turner; Fiscal Year: 2005
    ..In addition, thousands-of-tons of OP compounds are used as pesticides and are annually released into the environment...
  64. Molecular Mechanisms of Endocrine Disruption in Bass
    Nancy D Denslow; Fiscal Year: 2011
    ..plasma hormone levels have been observed in largemouth bass living in ecosystems polluted with organochlorine pesticides (OCPs), including the Superfund site at Lake Apopka and its surrounding muck farms, suggesting that OCP exposure ..
  65. A Microfluidic Biochip for Rapid Screening of Pesticide Residue
    Xiaoli Su; Fiscal Year: 2010
    ..Many pesticides, particularly herbicides, can inhibit photosynthesis in a concentration-dependent manner...
  66. Realtime Monitoring of Trace Amounts of Pesticides from Water Using Carbo
    ANNE M contact SCHWARTZ; Fiscal Year: 2010
    ..Development of a Field Applicable Real-time Remote Monitoring Sensor Device Capable of Detecting multiple pesticides simultaneously in fluid or surface water...
  67. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2004
    ..neurotoxins such as paraoxon, sarin, soman, VX, and Russian-VX, are a broad class of chemicals commonly used as pesticides and chemical warfare (CW) agents...
  68. OTHER FUNCTIONS TAS::75 0849::TAS AGRICULTURAL HEALTH STUDY PHASE IV--MOD 3:
    Marsha Dunn; Fiscal Year: 2012
    ..1993-1997 (during Phase I of the AHS) when they obtained or renewed their license to apply restricted use pesticides;spouses were recruited largely by questionnaires brought home by the pesticide applicator (81%)...
  69. CHLORINATED HYDROCARBONS EFFECTS ON MAMMALIAN SYSTEMS
    David Kupfer; Fiscal Year: 2003
    ..This study will examine the interaction of environmental pollutants, primarily pro-estrogenic/estrogenic pesticides and structurally related compounds (e.g...
  70. Maternal Pesticide Exposure and Pregnancy Outcomes
    Russ Hauser; Fiscal Year: 2009
    Although the use of polychlorinated biphenyls (PCBs) and many of the chlorinated pesticides, including DDT, are now prohibited or restricted, there remains concern over their potential human health effects because they persist in the ..