anion exchange resins

Summary

Summary: High-molecular-weight insoluble polymers that contain functional cationic groups capable of undergoing exchange reactions with anions.

Top Publications

  1. ncbi Characterization and application of strong ion-exchange membrane adsorbers as stationary phases in high-performance liquid chromatography of proteins
    O W Reif
    , , Germany
    J Chromatogr A 654:29-41. 1993
  2. ncbi Impact of multiple re-use of anion-exchange chromatography media on virus removal
    Lenore Norling
    Department of Recovery Sciences, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA
    J Chromatogr A 1069:79-89. 2005
  3. ncbi Analysis of carbohydrates by anion exchange chromatography and mass spectrometry
    Cees Bruggink
    Dionex B V, Lange Bunder 5, 4854 MB Bavel, The Netherlands
    J Chromatogr A 1085:104-9. 2005
  4. ncbi Evaluation and application of anion exchange resins to measure groundwater uranium flux at a former uranium mill site
    Valerie Stucker
    Department of Chemistry and Geochemistry, Colorado School of Mines, Golden, CO, USA
    Water Res 45:4866-76. 2011
  5. ncbi Effects of bovine serum albumin heterogeneity on frontal analysis with anion-exchange media
    A K Hunter
    Department of Chemical Engineering, University of Virginia, Charlottesville 22903-2442, USA
    J Chromatogr A 937:13-9. 2001
  6. ncbi Albumin recovery with centrifugal adsorption technology (CAT)
    D J Peet
    Kluyver Laboratory for Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands
    Biotechnol Bioeng 78:237-50. 2002
  7. ncbi Hybrid anion exchanger for trace phosphate removal from water and wastewater
    Lee M Blaney
    Department of Civil and Environmental Engineering, Lehigh University, 13 East Packer Avenue, Bethlehem, PA 18015, USA
    Water Res 41:1603-13. 2007
  8. ncbi pH Transitions in ion-exchange systems: role in the development of a cation-exchange process for a recombinant protein
    Sanchayita Ghose
    Product Recovery, Immunex Corporation, 51 University Street, Seattle, Washington 98101, USA
    Biotechnol Prog 18:530-7. 2002
  9. ncbi Fabrication and characterization of superporous cellulose bead for high-speed protein chromatography
    Dong Mei Wang
    Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
    J Chromatogr A 1146:32-40. 2007
  10. ncbi Separation of synthetic oligonucleotide dithioates from monothiophosphate impurities by anion-exchange chromatography on a mono-q column
    Xianbin Yang
    Sealy Center for Structural Biology and Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch at Galveston, TX 77555, USA
    Anal Biochem 306:92-9. 2002

Detail Information

Publications215 found, 100 shown here

  1. ncbi Characterization and application of strong ion-exchange membrane adsorbers as stationary phases in high-performance liquid chromatography of proteins
    O W Reif
    , , Germany
    J Chromatogr A 654:29-41. 1993
    ..Appropriate conditions were defined for the separation of human serum and for the isolation of subtilisin Carlsberg and beta-galactosidase from cell culture supernatants...
  2. ncbi Impact of multiple re-use of anion-exchange chromatography media on virus removal
    Lenore Norling
    Department of Recovery Sciences, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA
    J Chromatogr A 1069:79-89. 2005
    ....
  3. ncbi Analysis of carbohydrates by anion exchange chromatography and mass spectrometry
    Cees Bruggink
    Dionex B V, Lange Bunder 5, 4854 MB Bavel, The Netherlands
    J Chromatogr A 1085:104-9. 2005
    ..Furthermore mono-, di-, tri-, and oligosaccharides were detected in chicory coffee, honey and beer samples...
  4. ncbi Evaluation and application of anion exchange resins to measure groundwater uranium flux at a former uranium mill site
    Valerie Stucker
    Department of Chemistry and Geochemistry, Colorado School of Mines, Golden, CO, USA
    Water Res 45:4866-76. 2011
    Laboratory tests and a field validation experiment were performed to evaluate anion exchange resins for uranium sorption and desorption in order to develop a uranium passive flux meter (PFM)...
  5. ncbi Effects of bovine serum albumin heterogeneity on frontal analysis with anion-exchange media
    A K Hunter
    Department of Chemical Engineering, University of Virginia, Charlottesville 22903-2442, USA
    J Chromatogr A 937:13-9. 2001
    ..Breakthrough experiments carried out using dimer-free BSA confirm that the extreme tailing observed with the commercial samples is curtailed by removing the dimer...
  6. ncbi Albumin recovery with centrifugal adsorption technology (CAT)
    D J Peet
    Kluyver Laboratory for Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC Delft, The Netherlands
    Biotechnol Bioeng 78:237-50. 2002
    ..The resulting equipment dimensions proved to be very small indeed, making CAT a potentially very attractive technology...
  7. ncbi Hybrid anion exchanger for trace phosphate removal from water and wastewater
    Lee M Blaney
    Department of Civil and Environmental Engineering, Lehigh University, 13 East Packer Avenue, Bethlehem, PA 18015, USA
    Water Res 41:1603-13. 2007
    ..HAIX combines durability and mechanical strength of polymeric anion exchange resins with high sorption affinity of hydrated ferric oxide (HFO) toward phosphate...
  8. ncbi pH Transitions in ion-exchange systems: role in the development of a cation-exchange process for a recombinant protein
    Sanchayita Ghose
    Product Recovery, Immunex Corporation, 51 University Street, Seattle, Washington 98101, USA
    Biotechnol Prog 18:530-7. 2002
    ..The results from this study were applied to the cation-exchange step for a recombinant protein that was sensitive to pH excursions to help maintain activity of the protein during the purification process...
  9. ncbi Fabrication and characterization of superporous cellulose bead for high-speed protein chromatography
    Dong Mei Wang
    Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
    J Chromatogr A 1146:32-40. 2007
    ..All the results exhibited the superior characteristics of the SC bead as a potential medium for high-speed protein chromatography...
  10. ncbi Separation of synthetic oligonucleotide dithioates from monothiophosphate impurities by anion-exchange chromatography on a mono-q column
    Xianbin Yang
    Sealy Center for Structural Biology and Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch at Galveston, TX 77555, USA
    Anal Biochem 306:92-9. 2002
    ..Thiocyanate, SCN-, as eluting anion, can be used to purify oligonucleotides containing a high percentage of phosphorodithioate linkages in lower salt concentrations and provides better separation than chloride as eluting anion...
  11. ncbi Retention studies of DNA on anion-exchange monolith chromatography Binding site and elution behavior
    Shuichi Yamamoto
    Department of Chemical Engineering, School of Engineering, Applied Medical Engineering Science Division, Graduate School of Medicine, Yamaguchi University, Tokiwadai, Ube 755 8611, Japan
    J Chromatogr A 1144:155-60. 2007
    ..5M) and a high flow-velocity (2.7 cm/min)...
  12. ncbi Analysis of carbohydrates in plants by high-performance anion-exchange chromatography coupled with electrospray mass spectrometry
    Cedric Guignard
    Public Research Center Gabriel Lippmann, Environment and Biotechnologies Research Unit, 41 rue du Brill, L 4422 Belvaux, Luxembourg
    J Chromatogr A 1085:137-42. 2005
    ..Different responses to water deficit and re-hydration were obtained for several carbohydrates, suggesting different roles in osmoprotection processes...
  13. ncbi Validation of a high-performance liquid chromatographic assay for the quantification of adenovirus type 5 particles
    J Transfiguracion
    Animal Cell Technology and Downstream Processing Group, Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec
    J Chromatogr B Biomed Sci Appl 761:187-94. 2001
    ..14 x 10(9) VP/ml and a slope of 3.04 x 10(5) VP/ml. The recovery of the method varied between 88 and 106% in all of the lysate samples investigated which is statistically similar to 100% recovery at 95% confidence interval...
  14. ncbi Application of a chromatography model with linear gradient elution experimental data to the rapid scale-up in ion-exchange process chromatography of proteins
    Takashi Ishihara
    CMC R and D Laboratories, Pharmaceutical Division, Kirin Brewery Co Ltd, Takasaki, Gunma 370 0013, Japan
    J Chromatogr A 1162:34-40. 2007
    ..Resolution, recovery and purity were examined in order to verify the proposed method...
  15. ncbi Sub-ambient temperature effects on the separation of monosaccharides by high-performance anion-exchange chromatography with pulse amperometric detection. Application to marine chemistry
    C Panagiotopoulos
    Laboratoire de Microbiologie Marine, CNRS-INSU UMR 6117, , , France
    J Chromatogr A 920:13-22. 2001
    ..This method gave acceptable results for detection of marine sugars...
  16. ncbi An anion-exchange high-performance liquid chromatography method coupled to total organic carbon determination for the analysis of water-soluble organic aerosols
    Valeriana Mancinelli
    Institute of Atmospheric Sciences and Climate, National Research Council, Via Gobetti 101, 40129 Bologna, Italy
    J Chromatogr A 1149:385-9. 2007
    ....
  17. ncbi Purification and identification of N-glycolylneuraminic acid (Neu5Gc) from the holothuroidea Gumi, Cucumaria echinata
    T Sumi
    Kyushu National Industrial Research Institute, Tosu, Saga, Japan
    Prep Biochem Biotechnol 31:135-46. 2001
    ..The purity of Neu5Gc was more than 99%. This is the first report of purification and identification of Neu5Gc from holothuroidea by using anion exchange chromatography, GC-MS, and 1H-NMR...
  18. ncbi Characterization of membrane-associated proteasomes in WB rat liver epithelial cells
    M T Khan
    Department of Pathology and Cell Biology, Thomas Jefferson University School of Medicine, Philadelphia, Pennsylvania 19107, USA
    Arch Biochem Biophys 385:99-107. 2001
    ..Thus, the principal difference between cytosolic and membrane activity was that the latter fractions contained a novel membrane-associated LC-insensitive protease(s) catalyzing three of the major peptidase activities of the proteasome...
  19. ncbi Capillary electrophoresis and high-performance anion exchange chromatography for monitoring caseinoglycomacropeptide sialylation
    Y Daali
    Laboratory of Pharmaceutical Analytical Chemistry, University of Geneva, Bd d'Yvoy 20, 1211 Geneva 4, Switzerland
    J Pharm Biomed Anal 24:849-56. 2001
    ..Sialic acid was determined using high performance anion exchange chromatography coupled with pulsed amperometric detection. Results were compared to those obtained by alternative techniques, such as colorimetric and enzymatic methods...
  20. ncbi Ion exchange chromatography of antibody fragments
    Anders Ljunglöf
    GE Healthcare, Bio Sciences AB, SE 751 84 Uppsala, Sweden
    Biotechnol Bioeng 96:515-24. 2007
    ..Such results are in agreement with recent studies related to ion exchange of whole antibody molecules under similar conditions...
  21. ncbi Adjustable-capacity anion-exchange separator
    Andy Woodruff
    Dionex Corporation, Sunnyvale, CA 94085, USA
    J Chromatogr A 956:35-41. 2002
    ..Some of the unique chromatographic properties of this prototype column will be illustrated as well...
  22. ncbi Evaluation of three expanded bed adsorption anion exchange matrices with the aid of recombinant enhanced green fluorescent protein overexpressed in Escherichia coli
    C Cabanne
    Ecole Supérieure de Technologie des Biomolécules de Bordeaux ESTBB, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Chromatogr B Analyt Technol Biomed Life Sci 808:91-7. 2004
    ..It is composed of little size and density beads which lead to a higher exchange surface and then a better mass transfer...
  23. ncbi High-performance anion-exchange chromatography coupled with pulsed amperometric detection and capillary zone electrophoresis with indirect ultra violet detection as powerful tools to evaluate prebiotic properties of fructooligosaccharides and inulin
    C Corradini
    Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica, Universita degli Studi di Parma, Parco Area delle Science 17A, Parma 43100, Italy
    J Chromatogr A 1054:165-73. 2004
    ..e. temperature, voltage and percentage of methanol added to the background electrolyte were investigated...
  24. ncbi Effect of the concentration of ionogenic groups in the sorbent on the separation of protein mixtures
    A A Demin
    Institute of Macromolecular Compounds, Russian Academy of Science, Bolshoi pr 31, St Petersburg, 199004, Russia
    J Chromatogr A 1006:185-93. 2003
    ....
  25. ncbi Purification of the Ndc80 kinetochore subcomplex from Xenopus eggs
    Mark L McCleland
    Department of Biochemistry and Molecular Genetics, University of Virginia Medical School, Charlottesville, VA, USA
    Methods Mol Biol 296:383-91. 2005
    ..With minor modification and manipulation of Xenopus egg extracts, this protocol can easily be adapted for purification of other protein complexes...
  26. ncbi Isoenzymatic forms of human cytidine deaminase
    S Vincenzetti
    Dipartimento di Scienze Veterinarie, Dipartimento di Scienze Morfologiche e Biochimiche Comparate and Dipartimento di Scienze Chimiche, Universita di Camerino, via circonvallazione 93 95, 62024 Matelica MC, Italy
    Protein Eng Des Sel 17:871-7. 2004
    ..Furthermore, for both CDA 1 and CDA 2 some substrates and inhibitors of CDA were assayed, with the aim of demonstrating different kinetic behavior between the two natural variants...
  27. ncbi Preparation of strong anion-exchange chromatographic packings based on monodisperse polymeric beads and their application in the separation of biopolymers
    Bolin Gong
    Key Laboratory of Energy and Chemical Engineering, Ningxia University, Yinchuan 750021, P R China
    Anal Bioanal Chem 382:1590-4. 2005
    ..The SAX resin was also used for rapid separation and purification of recombinant human stem cell factor (rhSCF) from a crude extract solution in only one step. The purity of the purified of rhSCF was >92.4%...
  28. ncbi Comparisons of disposable and conventional silver working electrode for the determination of iodide using high-performance anion-exchange chromatography with pulsed amperometric detection
    Lina Liang
    Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, P O Box 2871, Beijing 100085, China
    J Chromatogr A 1085:37-41. 2005
    ..5 microg/L (10 microL injection, three times of the baseline noise)...
  29. ncbi Purification and characterization of the deoxynucleoside monophosphate kinase of bacteriophage T5
    Galina V Mikoulinskaia
    Pushchino Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, ave Nauki 6, Pushchino, Moscow Region 142290, Russia
    Protein Expr Purif 27:195-201. 2003
    ..A comparison of this amino acid sequence and those of known enzymes with a similar function suggests the presence of a nucleotide-binding site in the sequenced region...
  30. ncbi Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography
    Yan Zhu
    Department of Chemistry, Xixi Campus, Zhejiang University, Hangzhou 310028, China
    J Chromatogr A 1085:143-6. 2005
    ..Rate of recovery were between 98.23 and 105.42%, 99.48 and 103.57%, 97.96 and 103.23%, 98.46 and 102.40%, respectively. The method has successfully applied to the determination of the four sweeteners in drinks and preserved fruits...
  31. ncbi Selective recovery of gold from secondary sources by Dowex-50-X8 sorbed Rhodamine-B resin
    Sabir Syed
    Department of Chemistry, N A S College, Meerut 25001, India
    Ann Chim 92:1143-50. 2002
    ..The results of the proposed method are suggestive of its applicability to other gold containing secondary sources...
  32. ncbi Alternative high-performance liquid chromatographic peptide separation and purification concept using a new mixed-mode reversed-phase/weak anion-exchange type stationary phase
    Raquel Nogueira
    Christian Doppler Laboratory for Molecular Recognition Materials, Institute of Analytical and Food Chemistry, University of Vienna, Wahringerstrasse 38, A 1090 Vienna, Austria
    J Chromatogr A 1089:158-69. 2005
    ..For example, the yield of pure peptide per chromatographic run on RP/WAX phase was by a factor of about 15 higher compared to the standard gradient elution RP-purification protocol...
  33. ncbi The influence of homogenisation conditions on biomass-adsorbent interactions during ion-exchange expanded bed adsorption
    Jürgen J Hubbuch
    Institute of Biotechnology, Research Center Jülich GmbH, 52425 Julich, Germany
    Biotechnol Bioeng 94:543-53. 2006
    ..The new approach, however, led to a system where anion exchange as capture step became possible, however, to the cost of binding capacity...
  34. ncbi Evaluation of methods for the extraction of nitrite and nitrate in biological fluids employing high-performance anion-exchange liquid chromatography for their determination
    Christopher C T Smith
    Department of Medicine, Royal Free and University College Medical School, Gower Street Campus, The Middlesex Hospital, Mortimer Street, London W1N 8AA, UK
    J Chromatogr B Analyt Technol Biomed Life Sci 779:201-9. 2002
    ..Our procedure may be suitable for routine determination of NO(2)(-) and NO(3)(-) in various biological fluids, e.g., plasma...
  35. ncbi Screening anion-exchange chromatographic matrices for isolation of onco-retroviral vectors
    Teresa Rodrigues
    ITQB IBET, Av da Republica EAN, P 2781 901 Oeiras, Portugal
    J Chromatogr B Analyt Technol Biomed Life Sci 837:59-68. 2006
    ..Fixed-bed DEAE FF and Q XL proved to be good candidates for purification of MoMLV derived vectors due to resulting high yields, 53+/-13% and 51+/-7%, respectively, while removing more than 99% of protein and 90% of the DNA contaminants...
  36. ncbi Flow microcalorimetric measurements for bovine serum albumin on reversed-phase and anion-exchange supports under overloaded conditions
    M E Thrash
    Department of Chemical Engineering, University of Cincinnati, OH 45221, USA
    J Chromatogr A 908:293-9. 2001
    ..Heats of adsorption of BSA on an ion-exchange support were also measured. Endothermic heats were obtained in all cases. The data indicate that the observed heat effects may be strongly influenced by the release of water from the surface...
  37. ncbi Adsorption equilibrium of fructosyltransferase on a weak anion-exchange resin
    Katarína Vanková
    Department of Chemical and Biochemical Engineering, Institute of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinskeho 9, 81237 Bratislava, Slovakia
    J Chromatogr A 1162:56-61. 2007
    ..The model fit provided the protein characteristic charge equal to 1.9, equilibrium constant 0.326, and steric factor 1.095 x 10(5)...
  38. ncbi Comparison of chromatographic ion-exchange resins VI. Weak anion-exchange resins
    Arne Staby
    Novo Nordisk A S, Protein Separation, Hagedornsvej 1, DK 2820, Gentofte, Denmark
    J Chromatogr A 1164:82-94. 2007
    ..The data presented in this paper may be used for selection of resins for testing in process development...
  39. ncbi Simple and rapid chromatographic method for the separation of major classes of ribosomal ribomononucleotides
    D A Popović
    Department of Biochemistry, Medical Faculty, Novi Sad, Yugoslavia
    J Chromatogr A 769:225-30. 1997
    ..Our method is competitive, in several respects, with modern HPLC techniques for the separation of ribomononucleotides...
  40. ncbi Theory and applications of a novel ion exchange chromatographic technology using controlled pH gradients for separating proteins on anionic and cationic stationary phases
    Latchezar I Tsonev
    CryoBioPhysica, Inc, Biomedical Research Institute, 12111 Parklawn Drive, Rockville, MD 20852, USA
    J Chromatogr A 1200:166-82. 2008
    ....
  41. ncbi Influence of column type and chromatographic conditions on the ion-exchange chromatography of immunoglobulins
    Y B Yang
    Separations Group, Inc, Hesperia, CA 92345, USA
    J Chromatogr A 743:171-80. 1996
    ..Significant differences in the chromatographic behavior (elution pattern, peak shape and selectivity) of the test samples are discussed in regard to the column type and the chromatographic conditions...
  42. ncbi Microcalorimetric characterization of the anion-exchange adsorption of recombinant cytochrome b5 and its surface-charge mutants
    D S Gill
    Department of Chemical Engineering, University of Houston, TX 77204-4792, USA
    J Chromatogr A 715:81-93. 1995
    ....
  43. ncbi Large-scale capture and partial purification of plasmid DNA using anion-exchange membrane capsules
    Shiying Zhang
    Pall Corporation, 8780 Ely Road, Pensacola, FL 32514, USA
    Biotechnol Appl Biochem 37:245-9. 2003
    ..The captured and eluted plasmid pool was found to have been concentrated 10-fold with a reduction in endotoxin of four orders of magnitude...
  44. ncbi Combined pH gradient and anion-exchange high-performance liquid chromatographic separation of oligodeoxyribonucleotides
    T Lu
    Department of Biochemical and Biophysical Sciences, University of Houston, TX 77204-5934
    J Chromatogr A 686:339-43. 1994
    ....
  45. ncbi Purification of recombinant human basic fibroblast growth factor: stability of selective sorbents under cleaning in place conditions
    F B Anspach
    GBF-National Research Centre for Biotechnology, Braunschweig, Germany
    J Chromatogr A 711:129-39. 1995
    ..By direct application of pooled fractions from Fractogel EMD-SO3- onto Heparin-Sepharose a highly pure product was obtained; however, the recovery after Heparin-Sepharose was only 30%...
  46. ncbi Adsorption of plasmid DNA on anion exchange chromatography media
    Christina Tarmann
    Department of Biotechnology, University of Applied Life Science and Natural Resources Vienna, Vienna, Austria
    J Sep Sci 31:2605-18. 2008
    ..Feed concentrations higher than 0.1 mg/mL pDNA pronounce this effect. Monolithic media showed the fastest adsorption rate and highest binding capacity with 13 mg pDNA per mL...
  47. ncbi Efficient purification of small unsaturated oligoglucuronides by reversed-phase chromatography
    Marie Laure Tavernier
    Laboratoire des Glucides, UMR CNRS 6219, Universite de Picardie Jules Verne, 33 rue Saint Leu, F 80039 Amiens, France
    J Chromatogr B Analyt Technol Biomed Life Sci 863:266-72. 2008
    ..7%) as eluent. Different selectivities and column stabilities were observed in this acidic condition. The scale up for semi-preparative applications enabled us to recover pure unsaturated oligoglucuronans without desalting step...
  48. ncbi Separation and determination of rare earth elements by Dowex 2-X8 resin using sodium trimetaphosphate as elution agent
    S K Sungur
    Department of Chemistry, Science and Letters Faculty, Istanbul Technical University, Turkey
    J Chromatogr A 874:311-7. 2000
    ..It has been seen that the elution peaks are narrow, tailing effects are very small, Dy and Y are well separated. Qualitative and quantitative determinations were realized by spectrofluorometry...
  49. ncbi Secondary interactions, an unexpected problem emerged between hydroxyl containing analytes and fused silica capillaries in anion-exchange micro-liquid chromatography
    A Castillo
    Research Institute for Pesticides and Water, Universitat Jaume I, E 12071 Castelló, Spain
    J Chromatogr A 1172:179-85. 2007
    ..0 and NH(4)NO(3)/NH(4)H(2)PO(4) at pH 8.7, were optimized and compared. Results showed better peak shapes for some species when hydrogen phosphate was added to the mobile phase...
  50. ncbi Selection of pH-related parameters in ion-exchange chromatography using pH-gradient operations
    Tangir Ahamed
    Department of Biotechnology, Delft University of Technology, Delft, The Netherlands
    J Chromatogr A 1194:22-9. 2008
    ..5 or anion-exchange chromatography (AEX) at pH 7.2 without lowering the salt concentration in the CCS. The performance of both CEX and AEX was predicted to be equal for this particular MAb capture...
  51. ncbi Liquid chromatographic and electrophoretic characterisation of extracellular beta-glucosidase of Pleurotus ostreatus grown in organic waste
    Helena Morais
    National Agronomical Station, Quinta do Marques, Oeiras, Portugal
    J Chromatogr B Analyt Technol Biomed Life Sci 770:111-9. 2002
    ....
  52. ncbi Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2
    H Chung
    Center for Cell Signaling, The University of Virginia, Charlottesville 22908, USA
    Biochemistry 38:10371-6. 1999
    ..Signals that affect phosphorylation or methylation of the C subunit of PP2A may promote subunit exchange and direct phosphatase activity to specific intracellular substrates...
  53. ncbi Comparison of byproduct formation in waters treated with chlorine and iodine: relevance to point-of-use treatment
    Emma Marie Smith
    Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, USA
    Environ Sci Technol 44:8446-52. 2010
    ..Although N-nitrosamines have been associated with oxidant contact with anion exchange resins, N-nitrosamine formation rapidly declined to low levels (4 ng/L) using the Lifestraw device after the ..
  54. ncbi The pathogenesis and treatment of pruritus and fatigue in patients with PBC
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 11:623-31. 1999
    ..The limited and inconsistent efficacy of conventional empiric therapies, such as anion exchange resins and rifampicin, has led to inconclusive trials of invasive experimental therapies, such as plasmapheresis, ..
  55. ncbi [Hyperlipidemia in children and adolescents: diagnosis and therapy]
    B Koletzko
    Kinderpoliklinik, Klinikum Innenstadt der Ludwig Maximilians Universität München
    Schweiz Med Wochenschr 128:477-85. 1998
    ..9 mmol/l) in the presence of additional risk factors. The drugs of first choice are anion exchange resins (colestyramine or colestipol) because of their well documented efficacy and safety...
  56. ncbi Uranium removal from contaminated groundwater by synthetic resins
    D H Phillips
    Environmental Engineering Research Centre, School of Planning, Architecture, and Civil Engineering, Queen s University of Belfast, Belfast BT9 5AG, Northern Ireland, UK
    Water Res 42:260-8. 2008
    ..This study presents an improved understanding of the selectivity and sorption kenetics of a range of ion-exchange resins that remove uranium from both low- and high-nitrate-containing groundwaters with varying pHs...
  57. ncbi Familial Hypercholesterolaemia Regression Study: a randomised trial of low-density-lipoprotein apheresis
    G R Thompson
    Department of Cardiology, Hammersmith Hospital, London
    Lancet 345:811-6. 1995
    ..Decreasing lipoprotein(a) seems to be unnecessary if LDL cholesterol is reduced to 3.4 mmol/L or less...
  58. ncbi Chromate (CrO(4)(2-)) and copper (Cu2+) adsorption by dual-functional ion exchange resins made from agricultural by-products
    Wayne E Marshall
    USDA ARS Southern Regional Research Center, 1100 Robert E Lee Blvd, P O Box 19687, New Orleans, LA 70179 0687, USA
    Water Res 40:2541-8. 2006
    ..The dual-functional resins adsorbed as much as or more of the marker ions compared to commercial cation or anion exchange resins used for comparison...
  59. ncbi Reduction of dioxins and polychlorinated biphenyls (PCBs) in human body
    Yoji Mochida
    Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba 260 8670, Japan
    Fukuoka Igaku Zasshi 98:106-13. 2007
    ..manner has been tested such as foods containing dietary fibers and chlorophyll, lipids (squalane etc) and anion exchange resins. Cholestyramine, a cholesterol lowering agent, was no efficacy in humans...
  60. ncbi The effects of cholestyramine and colestipol on the absorption of diclofenac in man
    S R al-Balla
    Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    Int J Clin Pharmacol Ther 32:441-5. 1994
    ..The in-vivo data suggest a reduction of diclofenac bioavailability when colestipol or cholestyramine is administered concomitantly...
  61. ncbi The effect of colestipol and cholestyramine on the systemic clearance of intravenous ibuprofen in rabbits
    Y M El-Sayed
    Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
    J Pharm Pharmacol 46:73-5. 1994
    ..This effect is thought to be due to augmentation of net biliary excretion through enteric binding...
  62. ncbi The effect of colestipol and cholestyramine on ibuprofen bioavailability in man
    M A al-Meshal
    Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
    Biopharm Drug Dispos 15:463-71. 1994
    The purpose of this study was to determine whether a concomitant single oral dose of one of the anion exchange resins colestipol hydrochloride (10 g) or cholestyramine (8 g) administered with ibuprofen (400 mg) would alter the ..
  63. ncbi Overexpression and purification of mammalian mitochondrial translational initiation factor 2 and initiation factor 3
    Domenick G Grasso
    Department of Chemistry, University of North Carolina at Chapel Hill, USA
    Methods Enzymol 430:59-78. 2007
    ..factor is then further purified by high-performance liquid chromatography or gravity chromatography on anion exchange resins. IF3(mt) has never been purified from any mammalian system...
  64. ncbi Hemoperfusion--state of art
    M Spighi
    Institute of Anaesthesiology and Resuscitation, University of Bologna
    Boll Soc Ital Biol Sper 69:661-7. 1993
    ..Next, the authors describe their experimental study with hemoperfusion using coated anion exchange resins for the treatment of acute respiratory insufficiency, the correction of metabolic alkalosis in pyloric ..
  65. ncbi Activity and characterization of secondary metabolites produced by a new microorganism for control of plant diseases
    Wen Hsiung Ko
    Department of Plant Pathology, National Chung Hsing University, Taichung, Taiwan
    N Biotechnol 27:397-402. 2010
    ..capsici although it was still strongly inhibitory to A. brassicicola. After treatment with cation or anion exchange resins, the extract lost its inhibitory effect against P. capsici but not A. brassicicola...
  66. ncbi Adsorptive removal of nitrilotris(methylenephosphonic acid) antiscalant from membrane concentrates by iron-coated waste filtration sand
    L Boels
    Wetsus, Centre of Excellence for Sustainable Water Technology, P O Box 1113, 8900 CC Leeuwarden, The Netherlands
    J Hazard Mater 182:855-62. 2010
    ..phosphonate-based antiscalant on this material was measured and compared with two commercially available anion exchange resins and activated carbon...
  67. ncbi An efficient and aseptic preparation of "sodium fluoride ((18)F) injection" in a GMP compliant facility
    Chih Hao K Kao
    Department of Nuclear Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    Ann Nucl Med 24:149-55. 2010
    ..This report introduces an efficient, low-cost and aseptic preparation of "Sodium fluoride ((18)F) injection" for PET scan...
  68. ncbi Anion chromatography using on-line recycled eluents
    Takashi Yokoyama
    Department of Chemistry, Faculty of Science, Okayama University of Science, 1 1 Ridai cho, Okayama 700 0005, Japan
    J Chromatogr A 1089:82-6. 2005
    ..excluded from the eluents using a mixture of strongly acidic cation-exchange resins and strongly basic anion exchange resins in the eluent reservoir...
  69. ncbi Decomposition of free chlorine with tertiary ammonium
    Hajime Katano
    Department of Bioscience, Fukui Prefectural University, Eiheiji, Fukui 910 1195, Japan
    Anal Sci 26:349-53. 2010
    ..The catalytic decomposition was observed also with the tertiary-ammonium-based anion-exchange resins. Furthermore, the anion-exchange resins exhibited the decomposition of not only free chlorine but also chloramines in water...
  70. ncbi Sorbent-based artificial liver devices: principles of operation, chemical effects and clinical results
    Benoît Carpentier
    Universite de Technologie de Compiegne, Biomechanics and Biomedical Engineering, Compiegne, France
    Expert Rev Med Devices 4:839-61. 2007
    ..Prometheus uses neutral and anion exchange resins to regenerate a plasma filtrate containing albumin and small globulins...
  71. ncbi Influence of surface chemistry of the substrate on the adsorption of Escherichia coli
    K J Hüttinger
    Institut für Chemische Technik, Universitat Karlsruhe
    Zentralbl Bakteriol Mikrobiol Hyg B 184:538-47. 1987
    ..of (1) polystyrene, hydroxymethylated, chloromethylated and aminomethylated polystyrene, (2) cation and anion exchange resins, (3) glass and siliconized glass using a shake test...
  72. ncbi Aqueous carbonic acid: a readily removable electrolyte for the recovery of [18F]fluoride from anion exchange resins
    D M Jewett
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109 0552
    Int J Rad Appl Instrum A 42:410-1. 1991
    ..Chloride was substantially retained on the column permitting separation of [18F]fluoride from the former...
  73. ncbi Biodiesel production using anionic ion-exchange resin as heterogeneous catalyst
    Naomi Shibasaki-Kitakawa
    Department of Chemical Engineering, Tohoku University, Aoba yama 6 6 07, Aoba ku, Sendai 980 8579, Japan
    Bioresour Technol 98:416-21. 2007
    ..A continuous transesterification reaction was carried out using an expanded bed reactor packed with the most active resin. The reactor system permitted the continuous production of ethyl oleate with a high conversion...
  74. ncbi Patented techniques for the extraction and isolation of secoisolari-ciresinol diglucoside from flaxseed
    Farah S Hosseinian
    University of Manitoba, Department of Food Science, Winnipeg, Manitoba, R3T 2N2 Canada
    Recent Pat Food Nutr Agric 1:25-31. 2009
    ..is enriched by a process involving either liquid-liquid partitioning or passing the aqueous phase through anion exchange resins or C18 resins. The SDG is recovered after evaporation of the water...
  75. ncbi Removal of perfluorooctane sulfonate from wastewater by anion exchange resins: effects of resin properties and solution chemistry
    Shubo Deng
    POPs Research Center, Department of Environmental Science and Engineering, Tsinghua University, Beijing, 100084, PR China
    Water Res 44:5188-95. 2010
    ..In this paper, six anion exchange resins with different polymer matrix, porosity, and functional group were evaluated for PFOS removal from ..
  76. ncbi New rapid analysis method demonstrates differences in 6-[18F] fluoro-L-dopa plasma input curves with and without carbidopa and in hemi-MPTP lesioned monkeys
    C A McLellan
    Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, MD 20892
    Int J Rad Appl Instrum A 42:847-54. 1991
    ..We have developed a new method that uses alumina extraction preceded by cation and anion exchange resins to determine the parent compound, [18F]Dopa and its critical metabolite 3-O-methyl-6-[18F]fluoro-L-dopa...
  77. ncbi Anion exchange resins for removal of reactive dyes from textile wastewaters
    Silke Karcher
    Department of Water Quality Control, Faculty III, TU Berlin, Germany
    Water Res 36:4717-24. 2002
    ..However, the weak basic type is only efficient up to pH 8. Alkaline regeneration works well for MP62, for S6328a acid regeneration works for most dyes...
  78. ncbi Natural organic matter (NOM) and pesticides removal using a combination of ion exchange resin and powdered activated carbon (PAC)
    Hugues Humbert
    Anjou Recherche Veolia Environnement, Chemin de la Digue, Maisons Laffitte Cedex, France
    Water Res 42:1635-43. 2008
    The combination of anion exchange resins (AERs) and powdered activated carbon (PAC) was studied to remove both natural organic matter (NOM) and pesticides...
  79. ncbi Optimized enrichment and purification of ferrocyanide for 13/12C and 15/14N isotope analysis of aqueous solutions
    Ulrike Schulte
    Lehrstuhl für Sediment und Isotopengeologie, Institut fur Geologie, Mineralogie und Geophysik, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    Water Res 44:5414-22. 2010
    ....
  80. ncbi Recovery and purification of no-carrier-added [18F]fluoride with bistrimethylsilylsulfate (BTMSS)
    G K Mulholland
    Division of Nuclear Medicine, University of Michigan, Ann Arbor 48109
    Int J Rad Appl Instrum A 42:1003-8. 1991
    ..The supports included calcium phosphate, anion exchange resins, alumina, borosilicate and porous carbon beads, to which [18F]fluoride was applied by absorption or ..
  81. ncbi Development and evaluation of an isotope dilution LC/MS method for the determination of total homocysteine in human plasma
    Bryant C Nelson
    Genzyme Corporation, Framingham, MA 01701, USA
    Anal Chem 75:775-84. 2003
    ..LC/MS performed well in relation to the other homocysteine methods in terms of its capability to accurately quantify plasma homocysteine over the normal range (5-15 micromol/L)...
  82. ncbi Cholesterol-lowering nutraceuticals and functional foods
    Zhen Yu Chen
    Food and Nutritional Sciences Programme, Department of Biochemistry, The Chinese University of Hong Kong, Shatin, NT, China
    J Agric Food Chem 56:8761-73. 2008
    ..This review summarizes the findings of recent studies on the production, application, efficacy, and mechanisms of popular cholesterol-lowering nutraceuticals and functional foods...
  83. ncbi Evolving concepts of the pathogenesis and treatment of the pruritus of cholestasis
    E A Jones
    Academic Medical Center, Amsterdam ZO, The Netherlands
    Can J Gastroenterol 14:33-40. 2000
    ..This assumption cannot be excluded but is not supported by convincing data. Empirical therapies such as anion exchange resins and rifampicin often appear to be partially efficacious...
  84. ncbi Treatment of Clostridium difficile infection
    Dale N Gerding
    Hines Veterans Affairs Hospital, Hines, IL 60141, USA
    Clin Infect Dis 46:S32-42. 2008
    ..difficile vaccine...
  85. ncbi Arsenate removal from water by a weak-base anion exchange fibrous adsorbent
    Md Rabiul Awual
    Department of Applied Chemistry and Biochemistry, Kumamoto University, Kurokami 2 39 1, Kumamoto 860 8555, Japan
    Water Res 42:689-96. 2008
    ..chloride and sulfate do not strongly interfere with uptake of arsenate species different from conventional anion exchange resins based on crosslinked polystyrene matrices...
  86. ncbi Monoclonal antibodies to chick intestinal receptors for 1,25-dihydroxyvitamin D3. Interaction and effects of binding on receptor function
    J W Pike
    J Biol Chem 259:1167-73. 1984
    ..receptor for DNA, as well as the ionic strength necessary to elute receptor from both cation and anion exchange resins was significantly reduced by prior incubation with excess antibody...
  87. ncbi Bioavailability of slowly cycling soil phosphorus: major restructuring of soil P fractions over four decades in an aggrading forest
    Daniel D Richter
    Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC 27708, USA
    Oecologia 150:259-71. 2006
    ..of P from mineral soil into tree biomass and O horizons, labile soil P was not diminished, as indexed by anion exchange resins, and NaHCO(3) and Mehlich III extractants...
  88. ncbi Weak partitioning chromatography for anion exchange purification of monoclonal antibodies
    Brian D Kelley
    Purification Process Development, Wyeth BioPharma, 1 Burtt Road, Andover, Massachusetts 01810, USA
    Biotechnol Bioeng 101:553-66. 2008
    ..The use of WPC with anion exchange resins enables a two-column cGMP purification platform to be used for many different mAbs...
  89. ncbi BVMO-catalysed dynamic kinetic resolution of racemic benzyl ketones in the presence of anion exchange resins
    Cristina Rodriguez
    Departamento de Quimica Organica e Inorganica, Instituto Universitario de Biotecnologia de Asturias, Universidad de Oviedo, c Julian Claveria 8, 33006, Oviedo, Spain
    Org Biomol Chem 8:1121-5. 2010
    ..Different parameters that affect to the efficiency of the enzymatic Baeyer-Villiger oxidation and racemisation were analyzed in order to optimize the activity and selectivity of the biocatalytic system...
  90. ncbi Raman spectroscopic detection for perchlorate at low concentrations
    Baohua Gu
    Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA
    Appl Spectrosc 58:741-4. 2004
    ..Further exploration and research may allow application of these techniques for in situ, real-time detection and monitoring of ClO4- in environmental samples at even lower concentrations...
  91. ncbi [Pruritus associated with cholestasis]
    Alvaro Terán
    Servicio de Aparato Digestivo, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Espana
    Gastroenterol Hepatol 33:313-22. 2010
    ..have proven efficacy in randomized clinical trials in patients with cholestatic disorders, such as anion exchange resins, rifampicin, opioid antagonists and ursodeoxycholic acid; the latter is especially useful in intrahepatic ..
  92. ncbi Application of superparamagnetic nanoparticles in purification of plasmid DNA from bacterial cells
    Chen Li Chiang
    Department of Chemical Engineering, Southern Taiwan University of Technology, 710 Yung Kang City, Tainan Hsien, Taiwan
    J Chromatogr B Analyt Technol Biomed Life Sci 822:54-60. 2005
    ..Thus, the separation and purification qualities of PEI-modified magnetic nanobeads as well as its ease of use surpass those of conventional anion-exchange resins...
  93. ncbi Temperature influence on the dynamic binding capacity of a monolithic ion-exchange column
    Igor Mihelic
    Faculty of Chemistry and Chemical Technology, University of Ljubljana, Askerceva 5, SI 1000 Ljubljana, Slovenia
    J Chromatogr A 987:159-68. 2003
    ..In the case of L-glutamic acid, an increase in the binding capacity was observed with temperature up to 20 degrees C. A further increase in temperature caused a decrease of the dynamic binding capacity...
  94. ncbi Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors
    Sergei Zolotukhin
    Powell Gene Therapy Center, 1600 SW Archer Road, College of Medicine, University of Florida, 32610 0266, Gainesville, FL 32610 0266, USA
    Methods 28:158-67. 2002
    ..The purified vector stocks are 99% pure with titers of 1 x 10(12) to 1 x 10(13)vector genomes/ml...
  95. ncbi Adsorption of an ionizable drug onto microspheres: experimental and modeling studies
    Vincent Boudy
    Service Recherche et Développement, Pharmacie Centrale des Hôpitaux de Paris, 7 rue du Fer à Moulin, 75005 Paris, France
    Int J Pharm 239:13-22. 2002
    ..Although significant indomethacin loading was obtained onto the DEAE microspheres, the rapid rate of diffusion is not compatible with sustained release properties sought for this type of microspheres...
  96. ncbi Simultaneous separation and analysis of water- and fat-soluble vitamins on multi-modal reversed-phase weak anion exchange material by HPLC-UV
    Romain Dabre
    Department of Analytical Chemistry, University of Vienna, Vienna, Austria
    J Sep Sci 34:761-72. 2011
    ..The validated method was finally employed for the analysis of the vitamin content of some commercially available supplement tablets...
  97. ncbi Preparation and characterization of prototypes for multi-modal separation media aimed for capture of negatively charged biomolecules at high salt conditions
    Bo Lennart Johansson
    Department of Polymer and Surface Chemistry, Research and Development, Amersham Biosciences, SE 751 84 Uppsala, Sweden
    J Chromatogr A 1016:21-33. 2003
    ..With these ligands recovery was often found to be low due to strong non-electrostatic interactions. However, for phenol derived anion-exchange media the recovery can be improved by desorption at high pH...
  98. ncbi Speciation of arsenic compounds in urine from occupationally unexposed and exposed persons in the U.K. using a routine LC-ICP-MS method
    Jackie Morton
    Health and Safety Laboratory, Buxton, United Kingdom
    J Anal Toxicol 30:293-301. 2006
    ..The urine samples from timber treatment workers exhibited significantly higher levels of four arsenic species (not AB) than those observed in both the control groups and the semi-conductor workers...
  99. ncbi Postinfective bile acid malabsorption: is this a long-term condition?
    Shyam Menon
    Department of Gastroenterology, Sandwell General Hospital, West Bromwich, UK
    Eur J Gastroenterol Hepatol 23:308-10. 2011
    ..We identified these patients retrospectively from our medical records and assessed their long-term clinical course...
  100. ncbi Membrane chromatography: protein purification from E. coli lysate using newly designed and commercial anion-exchange stationary phases
    Bharat V Bhut
    Department of Chemical and Biomolecular Engineering, Clemson University, 127 Earle Hall, Clemson, SC 29634, USA
    J Chromatogr A 1217:4946-57. 2010
    ....
  101. ncbi Plasmid adsorption to anion-exchange matrices: comments on plasmid recovery
    Peter Tiainen
    Department of Pure and Applied Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden
    Biotechnol J 2:726-35. 2007
    ..It was thus observed that polyelectrolyte complexes associated with a surface were much more difficult to dissociate than the equivalent soluble complexes...

Research Grants8

  1. Statins &Lymphoid Malignancy Risk in a Large Multi-Site Population-Based Cohort
    Marianne Ulcickas Yood; Fiscal Year: 2013
    ..e., anion exchange resins, fibrates, nicotinic acid, and ezetimibe)...
  2. CHALONE REGULATION OF HUMAN LYMPHOID NEOPLASMS
    David Ranney; Fiscal Year: 1980
    ..Partial purification of this batch preparation has been achieved by chromatography on cation and anion exchange resins. Final purification is currently being performed by high pressure liquid chromatography, using a C-18 ..
  3. CELLULAR BASIS OF ANTIATHEROGENESIS BY APOLIPOPROTEIN E
    Daniel Rader; Fiscal Year: 2001
    ..These studies will provide greater understanding of the role of the local inflammatory response in atherosclerosis and its regulation by apoE. ..
  4. CHEMISTRY OF THE POLYSACCHARIDE OF V CHOLERAE 0139
    C Bush; Fiscal Year: 2001
    ..Oligosaccharide fragments will test the hypothesis of a conformational epitope that depends on molecular size. The oligosaccharides are to be used in development of chemically modified protein conjugates for vaccine development. ..
  5. Gordon Research Conference: Lipoprotein Metabolism 2004
    Daniel Rader; Fiscal Year: 2004
    ....
  6. MECHANISM OF PI-RELATED DYSLIPIDEMIA AND ATHEROSCLEROSIS
    Daniel Rader; Fiscal Year: 2004
    ..These studies will provide novel insights into the mechanisms of PI-associated dyslipidemia and atherosclerosis. ..
  7. Mentored Career Development in Patient Oriented Research
    Daniel Rader; Fiscal Year: 2006
    ..abstract_text> ..
  8. HDL metabolism: Influence of extracellular lipases
    Daniel Rader; Fiscal Year: 2009
    ....