food additives

Summary

Summary: Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.

Top Publications

  1. ncbi Dietary exposures to mineral hydrocarbons from food-use applications in the United States
    J T Heimbach
    ENVIRON International Corporation, Arlington, VA 22203, USA
    Food Chem Toxicol 40:555-71. 2002
  2. ncbi Antioxidant nutrients and mycotoxins
    Faik Atroshi
    Department of Clinical Sciences, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Helsinki University, P O 57, FIN 00014, Helsinki, Finland
    Toxicology 180:151-67. 2002
  3. ncbi Aluminium content of some foods and food products in the USA, with aluminium food additives
    Salim M Saiyed
    College of Pharmacy, University of Kentucky Medical Center, Lexington, KY, USA
    Food Addit Contam 22:234-44. 2005
  4. ncbi Extra-phosphate load from food additives in commonly eaten foods: a real and insidious danger for renal patients
    Omar Benini
    Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Pisa, Italy
    J Ren Nutr 21:303-8. 2011
  5. ncbi The food additives inulin and stevioside counteract oxidative stress
    Silviya Stoyanova
    Institute of Plant Biology, Biological Research Center, Szeged, Hungary
    Int J Food Sci Nutr 62:207-14. 2011
  6. ncbi Antimicrobial activity of essential oils and structurally related synthetic food additives towards selected pathogenic and beneficial gut bacteria
    W Si
    Food Research Program, Agriculture and Agri Food Canada, Guelph, Ont, Canada
    J Appl Microbiol 100:296-305. 2006
  7. ncbi Habitual high phosphorus intakes and foods with phosphate additives negatively affect serum parathyroid hormone concentration: a cross-sectional study on healthy premenopausal women
    Virpi E Kemi
    Calcium Research Unit, Department of Applied Chemistry and Microbiology, PO Box 66, FIN 00014, University of Helsinki, Finland
    Public Health Nutr 12:1885-92. 2009
  8. ncbi Reconsidering the effects of monosodium glutamate: a literature review
    Matthew Freeman
    OhioHealth, Columbus, Ohio, USA
    J Am Acad Nurse Pract 18:482-6. 2006
  9. ncbi Effect of food additives on hyperphosphatemia among patients with end-stage renal disease: a randomized controlled trial
    Catherine Sullivan
    Division of Nephrology, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH 44109, USA
    JAMA 301:629-35. 2009
  10. ncbi An update on alternatives to antimicrobial growth promoters for broilers
    Gerard Huyghebaert
    Ministry of the Flemish Community, Institute Agriculture Fishery Research ILVO Animal Nutrition Sciences, Scheldeweg 68, B 9090 Melle, Belgium
    Vet J 187:182-8. 2011

Detail Information

Publications263 found, 100 shown here

  1. ncbi Dietary exposures to mineral hydrocarbons from food-use applications in the United States
    J T Heimbach
    ENVIRON International Corporation, Arlington, VA 22203, USA
    Food Chem Toxicol 40:555-71. 2002
    ..Nearly all of the remainder, 0.404 mg/kg BW/day, is petrolatum, primarily from its use as trough grease in bakery applications. Exposure to paraffin and microcrystalline waxes combined is only 0.044 mg/kg BW/day...
  2. ncbi Antioxidant nutrients and mycotoxins
    Faik Atroshi
    Department of Clinical Sciences, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Helsinki University, P O 57, FIN 00014, Helsinki, Finland
    Toxicology 180:151-67. 2002
    ..However, supplementation with antioxidant nutrients to prevent mycotoxicosis has been controversial. The case for the use of supplemental antioxidant vitamins at the present time needs further research...
  3. ncbi Aluminium content of some foods and food products in the USA, with aluminium food additives
    Salim M Saiyed
    College of Pharmacy, University of Kentucky Medical Center, Lexington, KY, USA
    Food Addit Contam 22:234-44. 2005
    ..Many products provide a significant amount of Al compared to the typical intake of 3-12 mg/day reported from dietary Al studies conducted in many countries...
  4. ncbi Extra-phosphate load from food additives in commonly eaten foods: a real and insidious danger for renal patients
    Omar Benini
    Department of Animal Pathology, Prophylaxis and Food Hygiene, University of Pisa, Pisa, Italy
    J Ren Nutr 21:303-8. 2011
    ..The extra amount of phosphorus which is consumed as a result of phosphate-containing food additives is a real challenge for patients with renal disease and for dieticians because it represents a "hidden" ..
  5. ncbi The food additives inulin and stevioside counteract oxidative stress
    Silviya Stoyanova
    Institute of Plant Biology, Biological Research Center, Szeged, Hungary
    Int J Food Sci Nutr 62:207-14. 2011
    ..Within the plant vacuole, these compounds could play a crucial role in antioxidant defense mechanisms to help survive stresses. Addition to food assists in natural sweetening, food stabilization and maximizes health impact...
  6. ncbi Antimicrobial activity of essential oils and structurally related synthetic food additives towards selected pathogenic and beneficial gut bacteria
    W Si
    Food Research Program, Agriculture and Agri Food Canada, Guelph, Ont, Canada
    J Appl Microbiol 100:296-305. 2006
    To assess the potential of essential oils and structurally related synthetic food additives in reducing bacterial pathogens in swine intestinal tract.
  7. ncbi Habitual high phosphorus intakes and foods with phosphate additives negatively affect serum parathyroid hormone concentration: a cross-sectional study on healthy premenopausal women
    Virpi E Kemi
    Calcium Research Unit, Department of Applied Chemistry and Microbiology, PO Box 66, FIN 00014, University of Helsinki, Finland
    Public Health Nutr 12:1885-92. 2009
    Foods can contain natural phosphorus (NP) and phosphate-containing food additives (AP). The main objective of the present study was to investigate whether NP and AP of habitual diets differ in their effects on markers of Ca metabolism...
  8. ncbi Reconsidering the effects of monosodium glutamate: a literature review
    Matthew Freeman
    OhioHealth, Columbus, Ohio, USA
    J Am Acad Nurse Pract 18:482-6. 2006
    ....
  9. ncbi Effect of food additives on hyperphosphatemia among patients with end-stage renal disease: a randomized controlled trial
    Catherine Sullivan
    Division of Nephrology, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH 44109, USA
    JAMA 301:629-35. 2009
    ..However, phosphorus-containing additives are increasingly being added to processed and fast foods. The effect of such additives on serum phosphorus levels is unclear...
  10. ncbi An update on alternatives to antimicrobial growth promoters for broilers
    Gerard Huyghebaert
    Ministry of the Flemish Community, Institute Agriculture Fishery Research ILVO Animal Nutrition Sciences, Scheldeweg 68, B 9090 Melle, Belgium
    Vet J 187:182-8. 2011
    ..There are a number of non-therapeutic alternatives, including enzymes, (in)organic acids, probiotics, prebiotics, etheric oils and immunostimulants. Their efficacy and mode of action are briefly described in this review...
  11. pmc Comparable postprandial glucose reductions with viscous fiber blend enriched biscuits in healthy subjects and patients with diabetes mellitus: acute randomized controlled clinical trial
    Alexandra L Jenkins
    Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital and Li Ka Shing Knowledge Institute, 70 Richmond St E, Toronto, Ontario, Canada
    Croat Med J 49:772-82. 2008
    ..To compare the blood glucose-lowering effect of a highly viscous fiber blend (VFB) added to a starchy snack on postprandial glycemia between healthy participants and participants with diabetes mellitus...
  12. pmc Phosphorus-containing food additives and the accuracy of nutrient databases: implications for renal patients
    Catherine M Sullivan
    Division of Nephrology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio 44109, USA
    J Ren Nutr 17:350-4. 2007
    ..Phosphorus-containing additives are increasingly being added to food products. We sought to determine the potential impact of these additives. We focused on chicken products as an example...
  13. ncbi In vitro evaluation of the erosive potential of orange juice modified by food additives in enamel and dentine
    Tais Scaramucci
    Department of Restorative Dentistry, School of Dentistry, University of Sao Paulo, Av Prof Lineu Prestes 2227, 05508 900 Sao Paulo, SP, Brazil
    J Dent 39:841-8. 2011
    To evaluate the erosive potential of orange juice modified by food additives in enamel and dentine.
  14. pmc Contribution of food additives to sodium and phosphorus content of diets rich in processed foods
    Anna Carrigan
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
    J Ren Nutr 24:13-9, 19e1. 2014
    Phosphorus-based food additives increase the total phosphorus content of processed foods. However, the extent to which these additives augment total phosphorus intake per day is unclear.
  15. ncbi Antioxidant activity of resveratrol compared with common food additives
    M A Murcia
    Department of Food Science, Veterinary Faculty, University of Murcia, Spain
    J Food Prot 64:379-84. 2001
    ..The ability to scavenge HOCI was, in decreasing order, PG > resveratrol > alpha-tocopherol > phenol. The other compounds did not scavenge HOCl...
  16. ncbi Food additives such as sodium sulphite, sodium benzoate and curcumin inhibit leptin release in lipopolysaccharide-treated murine adipocytes in vitro
    Christian Ciardi
    Department of Internal Medicine I, Anichstrasse 35, Innsbruck Medical University, A 6020 Innsbruck, Austria
    Br J Nutr 107:826-33. 2012
    ..As the daily intake of food additives has increased substantially, the aim of the present study was to investigate a potential influence of food ..
  17. ncbi The role of histamine degradation gene polymorphisms in moderating the effects of food additives on children's ADHD symptoms
    Jim Stevenson
    School of Psychology, University of Southampton, Highfield, Southampton, SO17 1BJ, England
    Am J Psychiatry 167:1108-15. 2010
    b>Food additives can exacerbate ADHD symptoms and cause non-immunoglobulin E-dependent histamine release from circulating basophils...
  18. ncbi The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice
    I Martin-Kleiner
    Rudjer Boskovic Institute, Division of Molecular Medicine, PO Box 180, HR 10002, Zagreb, Croatia
    Food Chem Toxicol 39:717-27. 2001
    ..The clinoptilolite preparations ameliorated the sodium and chloride decline, whereas the effects on hematopoiesis were erratic...
  19. ncbi Synergistic interactions between commonly used food additives in a developmental neurotoxicity test
    Karen Lau
    Developmental Toxicopathology Unit, Department of Human Anatomy and Cell Biology, University of Liverpool, Sherrington Buildings, Liverpool L69 3GE, UK
    Toxicol Sci 90:178-87. 2006
    Exposure to non-nutritional food additives during the critical development window has been implicated in the induction and severity of behavioral disorders such as attention deficit hyperactivity disorder (ADHD)...
  20. ncbi Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity
    L Baad-Hansen
    Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark
    Cephalalgia 30:68-76. 2010
    ..Systolic BP was elevated in the high MSG session compared with low MSG and placebo. These findings add new information to the concept of MSG headache and craniofacial pain sensitivity...
  21. ncbi The comet assay with 8 mouse organs: results with 39 currently used food additives
    Yu F Sasaki
    Laboratory of Genotoxicity, Faculty of Chemical and Biological Engineering, Hachinohe National College of Technology, Tamonoki Uwanotai 16 1, Aomori 039 1192, Japan
    Mutat Res 519:103-19. 2002
    We determined the genotoxicity of 39 chemicals currently in use as food additives. They fell into six categories-dyes, color fixatives and preservatives, preservatives, antioxidants, fungicides, and sweeteners...
  22. ncbi Antioxidant evaluation in dessert spices compared with common food additives. Influence of irradiation procedure
    M Antonia Murcia
    Department of Food Science, Veterinary Faculty, Campus de Espinardo, University of Murcia, Apartado de Correos 4021, E 30008 Murcia, Spain
    J Agric Food Chem 52:1872-81. 2004
    ..Irradiated samples did not show significant differences (p < 0.05) in the antioxidant activity with respect to the non-irradiated samples (1, 3, 5, and 10 kGy) in the assays used...
  23. ncbi Adverse reactions to food additives
    Brian G Wilson
    Allergy and Immunology Section, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Ann Allergy Asthma Immunol 95:499-507; quiz 507, 570. 2005
    To summarize the literature related to the classification of food additives and their reported adverse reactions and to provide a practical approach for evaluation of patients suspected of having such reactions.
  24. ncbi Hypersensitivity reactions to food additives
    Shahid Randhawa
    Allergy and Immunology Section, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130 3932, USA
    Curr Opin Allergy Clin Immunol 9:278-83. 2009
    To provide an updated concise review on food additives adverse reactions, diagnosis, and management.
  25. ncbi Dietary strategies to counteract the effects of mycotoxins: a review
    F Galvano
    Dipartimento di Scienze e Tecnologie Agroforestali ed Ambientali, Universita di Reggio, Gallina di Reggio Calabria, Italy
    J Food Prot 64:120-31. 2001
    ....
  26. ncbi Rapid and convenient method for preparing aurapten-enriched product from hassaku peel oil: implications for cancer-preventive food additives
    Yasuo Takahashi
    Wakayama Agricultural Processing Research Corporation, 398 Tsukatsuki, Momoyama Chou, Naga gun, Wakayama 649 61, Japan
    J Agric Food Chem 50:3193-6. 2002
    ..The stability of aurapten in the aurapten-enriched preparation was higher than that of purified aurapten. These results suggest that aurapten is readily recovered from hassaku peel oil using SP70, and thus may be used as a food additive...
  27. ncbi Marker constituents of the natural antioxidant Eucalyptus leaf extract for the evaluation of food additives
    Yoshiaki Amakura
    College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime, Japan
    Biosci Biotechnol Biochem 73:1060-5. 2009
    ..Eucalyptus leaf extract, the UV-absorbing constituents of two eucalyptus leaf extracts registered as food additives (eucalyptus A and B) were investigated...
  28. ncbi Antioxidant properties of Mediterranean spices compared with common food additives
    M Martínez-Tomé
    Department of Food Science, Veterinary Faculty, University of Murcia, Spain
    J Food Prot 64:1412-9. 2001
    ..annatto, cumin, oregano, sweet and hot paprika, rosemary, and saffron) at 5% concentration and of common food additives (butylated hydroxyanisole [BHA], butylated hydroxytoluene [BHT], and propyl gallate) at 100 microg/g are ..
  29. ncbi Simultaneous determination of some food additives in soft drinks and other liquid foods by flow injection on-line dialysis coupled to high performance liquid chromatography
    Orawan Kritsunankul
    Department of Chemistry, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand
    Talanta 84:1342-9. 2011
    ..on-line dialysis was developed for sample pretreatment prior to the simultaneous determination of some food additives by high performance liquid chromatography (FID-HPLC)...
  30. ncbi Urinary metabolites of histamine and leukotrienes before and after placebo-controlled challenge with ASA and food additives in chronic urticaria patients
    G Di Lorenzo
    Dipartimento di Medicina Clinica e delle Patologie Emergenti, Universita degli Studi di Palermo, Italy
    Allergy 57:1180-6. 2002
    ..We aimed to determine urinary metabolites of both histamine and leukotrienes (LTs) in patients affected by chronic urticaria (CU)...
  31. ncbi One hundred years of commercial food carbohydrates in the United States
    James N BeMiller
    Whistler Center for Carbohydrate Research, Department of Food Science, Purdue University, West Lafayette, Indiana 47907, USA
    J Agric Food Chem 57:8125-9. 2009
    ..Exceptions are the introduction of maltodextrins and major developments in the high-fructose syrup industry, which occurred in the 1970s...
  32. ncbi Adverse reactions to food additives
    Ronald A Simon
    Division of Allergy, Asthma, and Immunology, Scripps Clinic, 10666 N Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Allergy Asthma Rep 3:62-6. 2003
    ..with asthma or chronic idiopathic urticaria/angioedema whose conditions are exacerbated after ingestion of food additives. Many of these reports are characterized by poorly controlled challenge procedures...
  33. ncbi [Studies on estrogenic activities of food additives with human breast cancer MCF-7 cells and mechanism of estrogenicity by BHA and OPP]
    Tomoko Okubo
    Department of Environmental Health, The Tokyo Metropolitan Research Laboratory of Public Health, 3 24 1 Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
    Yakugaku Zasshi 123:443-52. 2003
    Estrogenic activities of more than 90 chemicals including food additives, foodstuffs of plant origin, and some chemicals, which could be orally ingested, were examined by assaying estrogen receptor (ER)-dependent proliferation of MCF-7 ..
  34. ncbi Blocking of Pseudomonas aeruginosa and Ralstonia solanacearum Lectins by plant and microbial branched polysaccharides used as food additives
    Keren D Zinger-Yosovich
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    J Agric Food Chem 57:6908-13. 2009
    ..for assaying the pathogenic lectin-blocking abilities of some plant and microbial polysaccharidic food additives, adding the mannophilic plant lectin Con A as a reference...
  35. ncbi A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins
    Russell L Blaylock
    Belhaven College, Jackson, Mississippi, USA
    Altern Ther Health Med 15:56-60. 2009
    ..In addition, a number of environmental neurotoxins, such as fluoride, lead, cadmium, and aluminum, can result in these pathological and biochemical changes...
  36. ncbi Filamentous fungi for production of food additives and processing aids
    David B Archer
    School of Biology, University of Nottingham, University Park, NG7 2RD, Nottingham, UK
    Adv Biochem Eng Biotechnol 111:99-147. 2008
    ..In this review chapter we focus on the use of fungi in the production of food additives but take a largely pre-genomic, albeit a mainly molecular, view of the topic.
  37. ncbi [Experimental model to induce obesity in rats]
    Vinicius Von Diemen
    Post Graduate Program in Surgery, UFRGS, Brazil
    Acta Cir Bras 21:425-9. 2006
    ....
  38. ncbi Isoflavones--safe food additives or dangerous drugs?
    Wolfgang Wuttke
    Department of Clinical and Experimental Endocrinology, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Ageing Res Rev 6:150-88. 2007
    ..Therefore, the following question arises for the clinician: Why should soy or red clover products containing isoflavone be recommended, if the positive effects are only negligible but the adverse effects serious?..
  39. ncbi Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro
    T J Schrader
    Toxicology Research Division, Food Directorate, Health Canada
    Toxicol Sci 53:278-88. 2000
    ..Thus, of the chemicals tested, some interact with the human androgen receptor in vitro as agonists, others as antagonists, and some as partial agonists/antagonists...
  40. ncbi Is the Melkersson-Rosenthal syndrome related to the exposure to food additives? A case report
    M L Pachor
    Instituto di Clinica Odontoiatrica, Universita di Verona, Italy
    Oral Surg Oral Med Oral Pathol 67:393-5. 1989
    ..a case of Melkersson-Rosenthal syndrome that occurred in an adult patient who experienced intolerance to the food additives sodium benzoate and tartrazine...
  41. ncbi The influence of food additives and related materials on lower bowel structure and function
    P M Newberne
    Boston University School of Medicine, Massachusetts
    Toxicol Pathol 16:184-97. 1988
    b>Food additives, drugs, and other chemicals are known to influence the lower gastrointestinal tract under some defined conditions, resulting in morphological alterations in the mucosa and other tissues, deranged absorption and excretion of ..
  42. ncbi Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
    Rob Stierum
    Physiological Sciences Department, TNO Quality of Life, Zeist, The Netherlands
    Toxicol Appl Pharmacol 207:179-88. 2005
    ..is shown in which gene expression profiling together with conventional biochemistry led to the discovery of novel markers for the hepatic effects of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole.
  43. ncbi Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives
    Jeffrey Cummings
    Cancer Research UK, Edinburgh Oncology Unit, Western General Hospital, Edinburgh, United Kingdom
    Cancer Res 63:8443-50. 2003
    ..Glucuronidation may represent a mechanism of intrinsic drug resistance in colon cancer open to modulation by a range of food additives and proprietary medicines.
  44. ncbi Adverse reactions to food additives
    B Wuthrich
    Department of Dermatology, University Hospital Zurich, Switzerland
    Ann Allergy 71:379-84. 1993
    b>Food additives can induce a wide range of adverse reactions in sensitive individuals. A prevalence of 0.03% to 0.23% is estimated...
  45. ncbi alpha- and beta-Thujones (herbal medicines and food additives): synthesis and analysis of hydroxy and dehydro metabolites
    N S Sirisoma
    Environmental Chemistry and Toxicology Laboratory, Department of Environmental Science, Policy and Management, 115 Wellman Hall, University of California, Berkeley, California 94720-3112, USA
    J Agric Food Chem 49:1915-21. 2001
    Essential oils containing alpha- and beta-thujones are important herbal medicines and food additives. The thujone diastereomers are rapidly metabolized convulsants acting as noncompetitive blockers of the gamma-aminobutyric acid-gated ..
  46. ncbi [Use and regulation of veterinary drugs in Japan and many foreign countries]
    Masakazu Horie
    Saitama Prefectural Institute of Public Health 639 1, Kamiokubo, Saitama, Saitama 338 0824, Japan
    Shokuhin Eiseigaku Zasshi 45:J211-5. 2004
  47. ncbi Nitrites, nitrates and N-nitrosoamines in Estonian cured meat products: intake by Estonian children and adolescents
    M Reinik
    Estonian Health Protection Inspectorate, Tartu Laboratory, PB 272, 50002 Tartu, Estonia
    Food Addit Contam 22:1098-105. 2005
    ..7 mg, that of nitrites was 0.83 mg and that of N-nitrosoamines was 0.073 microg. In the 2000-01 study, the calculated nitrite intake exceeded the acceptable daily intake by up to 140% for 1-6-year-old children and up to 105% in 2003-04...
  48. ncbi Methods of in vitro toxicology
    G Eisenbrand
    University of Kaiserslautern, Department of Chemistry Food Chemistry and Environmental Toxicology, PO Box 3049, D 67653, Kaiserslautern, Germany
    Food Chem Toxicol 40:193-236. 2002
    ..chemicals, and have also been taken into account sporadically for risk assessment purposes in the case of food additives. However, the range of food-associated compounds amenable to in vitro toxicology is considered much broader, ..
  49. ncbi In vitro studies on the evaluation of mycotoxin detoxifying agents for their efficacy on deoxynivalenol and zearalenone
    S Doll
    Institute of Animal Nutrition, Federal Agricultural Research Centre FAL, Braunschweig, Germany
    Arch Anim Nutr 58:311-24. 2004
    ..Nonetheless in vivo experiments are indispensable to proof the efficacy...
  50. ncbi Low tryptophan and protein in the diet during development increase the susceptibility to convulsions in adult rats
    Alfredo Feria-Velasco
    Depto Biología Celular y Molecular, Centro Universitario de Ciencias Biologicas y Agropecuarias, Universidad de Guadalajara, Km 15 5 Carr Guad Nogales, 45100 Las Agujas Nextipac, Zapopan, Jal, Mexico
    Neurochem Res 33:1484-91. 2008
    ....
  51. ncbi A high dietary intake of sodium glutamate as flavoring (ajinomoto) causes gross changes in retinal morphology and function
    Hiroshi Ohguro
    Department of Ophthalmology, Hirosaki University School of Medicine, 5 Zaifucho, Hirosaki 036 8562, Hirosaki, Japan
    Exp Eye Res 75:307-15. 2002
    ..The present study suggests that a diet with excess sodium glutamate over a period of several years may increase glutamate concentrations in vitreous and may cause retinal cell destruction...
  52. ncbi Lay discourses and beliefs related to food risks: an Australian perspective
    Deborah A Lupton
    School of Social Sciences and Liberal Studies, Charles Sturt University, Australia
    Sociol Health Illn 27:448-67. 2005
    ..The relevance of the Australian cultural context for these findings is discussed...
  53. ncbi Human health risk assessment of processing-related compounds in food
    Angelika M Tritscher
    International Programme on Chemical Safety, World Health Organization, CH 1211 Geneva 27, Switzerland
    Toxicol Lett 149:177-86. 2004
    ..Once this information becomes available, the health risk from acrylamide exposure through food can be assessed...
  54. ncbi Estimates of the theoretical maximum daily intake of phenolic antioxidants BHA, BHT and TBHQ in Brazil
    G C Maziero
    Department of Food Science, Faculty of Food Engineering, State University of Campinas, UNICAMP, SP, Brazil
    Food Addit Contam 18:365-73. 2001
    ..The estimates were based on maximum levels of use of the food additives specified in national food standards...
  55. ncbi Estimated daily intakes of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) antioxidants in Korea
    H J Suh
    Korea Health Industry Development Institute, 57 1 Noryangjin Dong, Seoul 156 800, Korea
    Food Addit Contam 22:1176-88. 2005
    ..00 to 14.42% of the ADI of each antioxidant. According to these results, the EDIs of BHA, BHT and TBHQ in Korea were significantly lower than ADI of these antioxidants established by the JECFA...
  56. ncbi An innovative approach to the determination of safety for a dietary ingredient derived from a new source: case study using a crystalline lutein product
    C L Kruger
    ENVIRON International Corporation, 4350 Fairfax Drive, Arlington, VA 22203, USA
    Food Chem Toxicol 40:1535-49. 2002
    ..It can be concluded that crystalline lutein is a safe and GRAS source of lutein for its proposed uses in food...
  57. ncbi Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin
    E O Farombi
    Department of Biochemistry, Drug Metabolism and Toxicology Research Laboratories, College of Medicine, University of Ibadan, Nigeria
    Hum Exp Toxicol 25:251-9. 2006
    ..The results indicate that dietary antioxidants have protective potential against oxidative stress induced by MSG and, in addition, suggest that active oxygen species may play an important role in its genotoxicity...
  58. ncbi Using ammonium-tolerant yeast isolates: Candida halophila and Rhodotorula glutinis to treat high strength fermentative wastewater
    Q Yang
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, P O Box 2871, Beijing 100085, China
    Environ Technol 24:383-90. 2003
    ..The residual COD of effluents from the yeast reactor could be further reduced to under 500 mg l(-1) by a combination process of activated sludge treatment and coagulation technologies...
  59. ncbi Influence of monosodium glutamate on circadian rhythms of lipid peroxidation products and antioxidants in rats
    Tamilarasan Manivasagam
    Department of Biochemistry, Faculty of Science, Annamalai University, Annamalainagar 608002, Tamilnadu, India
    Ital J Biochem 53:23-7. 2004
    ....
  60. ncbi Study on reduction of acrylamide in fried bread sticks by addition of antioxidant of bamboo leaves and extract of green tea
    Yu Zhang
    Department of Food Science and Nutrition, College of Biosystem Engineering and Food Science, Zhejiang University, 268 Kaixuan Road, Hangzhou, China 310029
    Asia Pac J Clin Nutr 16:131-6. 2007
    ..This study could be regarded as an important contribution on the reduction of acrylamide by natural antioxidants...
  61. ncbi Survey of residual solvents in natural food additives by standard addition head-space GC
    Y Uematsu
    Tokyo Metropolitan Research Laboratory of Public Health, Japan
    Food Addit Contam 19:335-42. 2002
    Residual levels of 12 solvents in 87 natural food additives (66 samples of food colours, 19 samples of natural antioxidants and two natural preservatives) collected between 1997 and 1999 were determined by automated head-space GC using ..
  62. ncbi Acrylamide in fried and roasted potato products: a review on progress in mitigation
    R J Foot
    European Snacks Association, London, UK
    Food Addit Contam 24:37-46. 2007
    ..More research is required into new potato varieties and the agronomical factors that influence the levels of asparagine and sugars in potatoes...
  63. ncbi Antioxidant activity of edible fungi (truffles and mushrooms): losses during industrial processing
    M Antonia Murcia
    Department of Food Science, Veterinary Faculty, University of Murcia, Spain
    J Food Prot 65:1614-22. 2002
    ..Losses of antioxidant activity were detected in the processed samples of these truffles and mushrooms...
  64. ncbi Who knows whether acrylamide in food is hazardous to humans?
    Fredrik Granath
    J Natl Cancer Inst 95:842-3. 2003
  65. ncbi [Assessment of mutagenic danger of food products]
    N B Maganova
    Vopr Pitan 73:35-7. 2004
    ..The majority of studied food additions, new foodstuffs and fodder did not induce mutagenic effect in the used experimental conditions...
  66. ncbi Assessment of feed additives and contaminants: an essential component of food safety
    Alberto Mantovani
    Dipartimento di Sanità Alimentare ed Animale, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    Ann Ist Super Sanita 42:427-32. 2006
    ..The possible effects of feed additives and contaminants on the overall safety and nutritional quality of human diet are discussed...
  67. ncbi [Problems of food authenticity]
    Ludwik Czerwiecki
    Zakład Analizy Zywności, Instytut Biotechnologii Przemysłu Rolno Spozywczego, 02 532 Warszawa, ul Rakowiecka 36
    Rocz Panstw Zakl Hig 55:9-19. 2004
    ..The role of chemometrics as a way of several analytical data processing was highlighted. It was pointed out at the necessity of more rigorous control of food to support of all activity in area of fight with fraud in food industry...
  68. ncbi Application of CE in hydrodynamically closed systems for analysis of bioactive compounds in food
    Frantisek Kvasnicka
    Department of Food Preservation and Meat Technology, Institute of Chemical Technology, Prague, Czech Republic
    Electrophoresis 28:3581-9. 2007
    ..There are two types of biologically active substances in food - naturally occurring and food additives. The bioactive compounds of food that will be mentioned in this review are inorganic and organic acids, amino ..
  69. ncbi Migration of substances from food packaging materials to foods
    Ioannis S Arvanitoyannis
    Department of Agriculture Crop and Livestock Production, School of Technological Sciences, University of Thessaly, Fytoko Street, 38446 Nea Ionia Magnesias, Volos, Hellas, Greece
    Crit Rev Food Sci Nutr 44:63-76. 2004
    ..Furthermore, the list of hazardous monomers, oligomers, and additives continues to augment in order to ensure that the consumer safety is in current agreement with the HACCP, which is continuously gaining ground...
  70. ncbi [Semicarbazide in food]
    Miyako Yamamoto
    Division of Safety Information on Drug, Food and Chemicals, National Institute of Health Sciences, Tokyo, Japan
    Shokuhin Eiseigaku Zasshi 45:J288-90. 2004
  71. ncbi The use of food consumption data in assessments of exposure to food chemicals including the application of probabilistic modelling
    Joyce Lambe
    Institute of European Food Studies, Biotechnology Institute, Trinity College, Dublin, Republic of Ireland
    Proc Nutr Soc 61:11-8. 2002
    ..The food chemicals for which exposure assessments are required include food additives, pesticide residues, environmental contaminants, mycotoxins, novel food ingredients, packaging-material ..
  72. ncbi Screening method for the addition of bovine blood-based binding agents to food using liquid chromatography triple quadrupole mass spectrometry
    Helen H Grundy
    DEFRA Central Science Laboratory, Sand Hutton, York YO41 1LZ, UK
    Rapid Commun Mass Spectrom 21:2919-25. 2007
    ..Fibrinopeptide A was found to be an effective marker in fresh, processed and cooked food matrices spiked with 5% (v/w) bovine binding agent...
  73. ncbi Occurrence and bioaccumulation study of PCDD and PCDF from mineral feed additives
    J Parera
    Laboratory of Dioxins, Mass Spectrometry Laboratory, Department of Ecotechnologies, IIQAB CSIC, Jordi Girona 18, 08034 Barcelona, Spain
    Chemosphere 73:S252-60. 2008
    ....
  74. ncbi [Acrylamide: Federal agency (Federal Institute for Risk Assessment) confirms food-watch and sees urgent need for action]
    Barbara F Hohl
    Foodwatch e V, Kommunikation, Barbara F Hohl
    Kinderkrankenschwester 24:467. 2005
  75. ncbi Application of uncertainty analysis in assessing dietary exposure
    Andy Hart
    Central Science Laboratory, Sand Hutton, YO41 1LZ, York, UK a hart gov uk
    Toxicol Lett 140:437-42. 2003
    ..Further work required to implement probabilistic approaches for dietary exposure assessment is discussed...
  76. ncbi Regulation of drugs used in feedlot diets
    Virginia R Fajt
    Veterinary Physiology and Pharmacology, Texas A and M University, College Station, TX 77843 4466, USA
    Vet Clin North Am Food Anim Pract 23:299-307, vii-viii. 2007
    ..The article includes a discussion of what a drug is, how drugs are approved in the United States, what uses of drugs in feedlot diets are legal or illegal, and what is on the horizon for future drug regulations...
  77. ncbi Determination of additives and organic contaminants in food by CE and CEC
    Mary C Boyce
    Edith Cowan University, Perth, WA, Australia
    Electrophoresis 28:4046-62. 2007
    ..The review highlights the strategies and approaches adopted in making CE suitable for the determination of analytes at residue level and in complicated matrices...
  78. ncbi [Study of development of analytical methods of veterinary drugs and other chemicals in food]
    Hiroyuki Nakazawa
    Department of Analytical Chemistry, Faculty of Pharmaceutical Science, Hoshi University, 2 4 41, Ebara, Shinagawa ku, Tokyo 142 8501, Japan
    Shokuhin Eiseigaku Zasshi 47:J311-4. 2006
  79. ncbi Food safety of allergic patients in hospitals: implementation of a quality strategy to ensure correct management
    P Sergeant
    Department of Internal Medicine, Clinical Immunology and Allergology, University Hospital, 29, Avenue de Lattre de Tassigny 54035, Nancy, France
    Eur Ann Allergy Clin Immunol 35:120-3. 2003
    ..As setting up food allergenic safety in hospitals in not addressed adequately in the European directives, it's judicious to draw attention of hospital catering managers and hospital canteen staff to this necessity...
  80. ncbi Safety evaluation of an alpha-amylase enzyme preparation derived from the archaeal order Thermococcales as expressed in Pseudomonas fluorescens biovar I
    Timothy D Landry
    The Dow Chemical Company, Midland, MI 48674, USA
    Regul Toxicol Pharmacol 37:149-68. 2003
    ..The enzyme was labile to pepsin digestion. Based on these data, BD5088 alpha-amylase preparation may be considered safe for use in food production such as corn wet milling...
  81. ncbi Does high glutamate intake cause obesity?
    M Hermanussen
    Aschauhof, Altenhof, Germany
    J Pediatr Endocrinol Metab 16:965-8. 2003
    ..We suggest abandoning the flavouring agent monosodium glutamate and reconsidering the recommended daily allowances of protein and amino acids, particularly during pregnancy...
  82. ncbi Aluminum bioavailability from the approved food additive leavening agent acidic sodium aluminum phosphate, incorporated into a baked good, is lower than from water
    Robert A Yokel
    Pharmaceutical Sciences Department, College of Pharmacy, University of Kentucky Medical Center, 725 Rose Street, Lexington, KY 40536 0082, USA
    Toxicology 227:86-93. 2006
    ..1mg from water, respectively) suggest food provides approximately 25-fold more Al to systemic circulation, and potential Al body burden, than does drinking water...
  83. ncbi Monosodium glutamate (MSG) and food labeling regulations
    Amy Lavine
    Food Drug Law J 62:349-73. 2007
  84. ncbi Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens
    W A Awad
    Institute of Nutrition, University of Veterinary Medicine, Vienna, Austria
    Poult Sci 85:974-9. 2006
    ..This indicates that in case of DON contamination of feedstuffs, the addition of PB would be a proper way to counteract the possible effects caused by this mycotoxin...
  85. ncbi Dietary exposure of children and teenagers to benzoates, sulphites, butylhydroxyanisol (BHA) and butylhydroxytoluen (BHT) in Beirut (Lebanon)
    L Soubra
    INRA INA P G, 16, rue Claude Bernard, 75005 Paris, France
    Regul Toxicol Pharmacol 47:68-77. 2007
    ..The aim of this paper is to assess the actual intake of the food additives listed above for a group of the Lebanese population (students aged between 9 and 18 years old) likely to be ..
  86. ncbi Development of databases for use in validation studies of probabilistic models of dietary exposure to food chemicals and nutrients
    C Leclercq
    INRAN National Research Institute for Food and Nutrition, Rome, Italy
    Food Addit Contam 20:S27-35. 2003
    ..used within the European Union FP5 Monte Carlo project to estimate, as accurately as possible, the intake of food additives, pesticide residues and nutrients...
  87. ncbi Design, development and validation of software for modelling dietary exposure to food chemicals and nutrients
    C McNamara
    Trinity Center for High Performance Computing, O Reilly Institute, Trinity College, Dublin, Ireland
    Food Addit Contam 20:S8-26. 2003
    ....
  88. ncbi Reducing human exposure to aflatoxin through the use of clay: a review
    T D Phillips
    Department of VIBS MS 4458, Texas A and M University, Veterinary Integrative Biosciences, College Station, TX 77843, USA
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:134-45. 2008
    ....
  89. ncbi Dietary sources of inorganic microparticles and their intake in healthy subjects and patients with Crohn's disease
    Miranda C E Lomer
    Gastrointestinal Laboratory, The Rayne Institute, St Thomas Hospital, London, UK
    Br J Nutr 92:947-55. 2004
    ..Nonetheless, microparticle-containing foods have now been identified which allows a low-microparticle diet to be further assessed in CD...
  90. ncbi Intake and risk assessment of nitrate and nitrite from New Zealand foods and drinking water
    B M Thomson
    ESR PO Box 29 181, Christchurch New Zealand
    Food Addit Contam 24:113-21. 2007
    ..Either the ADI is inappropriate and needs to be re-evaluated, or those individuals who have a high rate of conversion of nitrate to nitrite are at risk to adverse effects of nitrite exposure...
  91. ncbi A 90-day dietary study on kappa carrageenan with emphasis on the gastrointestinal tract
    Myra L Weiner
    FMC Corporation, P O Box 8, Princeton, NJ 08543, USA
    Food Chem Toxicol 45:98-106. 2007
    ..Commission Directive, 2004/45/EC of 16 April 2004 amending Directive 96/77/EC laying down specific purity criteria on food additives other than colors and sweeteners. Official Journal of European Union 20 April, 2004, L113/19-L113/21).
  92. ncbi Chronic toxicity and carcinogenicity of dietary administered ammonium sulfate in F344 rats
    Y Ota
    Division of Pathology, National Institute of Health Sciences, Setagaya Ku, Tokyo, Japan
    Food Chem Toxicol 44:17-27. 2006
    ..6% diet, which is equivalent to 256 and 284 mg/kg b.w./day in males and females, respectively, and the compound is non-carcinogenic under the conditions of the study...
  93. ncbi Evaluation of toxicity of green tea catechins with 90-day dietary administration to F344 rats
    S Takami
    Division of Pathology, National Institute of Health Sciences, 1 18 1 Kamiyoga, Setagaya Ku, Tokyo 158 8501, Japan
    Food Chem Toxicol 46:2224-9. 2008
    ..Based on above findings, the no observed adverse effect level (NOAEL) of GTC was estimated to be 1.25% (764mg/kg body weight/day for males and 820mg/kg body weight/day for females)...
  94. ncbi The eyes suppress a circadian rhythm of FOS expression in the suprachiasmatic nucleus in the absence of light
    C Beaule
    Center for Studies in Behavioral Neurobiology, Concordia University, 1455 de Maisonneuve Boulevard West, Montreal, Quebec H3G 1M8, Canada
    Neuroscience 121:253-7. 2003
    ..In contrast, we show here that removal of the eyes amplifies a normally dampened endogenous circadian rhythm within the SCN, indicating that the eyes can suppress the expression of specific rhythms within the SCN while promoting others...
  95. ncbi Obesity, voracity, and short stature: the impact of glutamate on the regulation of appetite
    M Hermanussen
    Aschauhof Altenhof Germany
    Eur J Clin Nutr 60:25-31. 2006
    ..Supraphysiological doses of GLU are toxic for neuronal cells...
  96. ncbi Thirteen-week repeated dose toxicity of Siraitia grosvenori extract in Wistar Hannover (GALAS) rats
    Meilan Jin
    Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3 5 8 Saiwai cho, Fuchu shi, Tokyo 183 8509, Japan
    Food Chem Toxicol 45:1231-7. 2007
    ..On the basis of these data, the no-observed-adverse effect level (NOAEL) of S. grosvenori extract in Wistar Hannover rats was considered to be 5% (2520 mg/kg/day in males and 3200 mg/kg/day in females) or more...
  97. ncbi [Effect of monosodium glutamate given orally on appetite control (a new theory for the obesity epidemic)]
    Jesús A Fernández-Tresguerres Hernández
    An R Acad Nac Med (Madr) 122:341-55; discussion 355-60. 2005
    ..In conclussion, oral administration of MSG during pregnancy and development in rats is able to significantly affect hypothalamic control of various hormones and increases appetite...
  98. ncbi Malnutrition impairs alveolar fluid clearance in rat lungs
    Tsutomu Sakuma
    Department of Thoracic Surgery, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Ishikawa 920 0293, Japan
    Am J Physiol Lung Cell Mol Physiol 286:L1268-74. 2004
    ....
  99. ncbi Lack of toxicity or carcinogenicity of S-170, a sucrose fatty acid ester, in F344 rats
    Midori Yoshida
    Department of Pathology, Sasaki Institute, 2 2 Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    Food Chem Toxicol 42:667-76. 2004
    ..37 g/kg/day in males and 2.80 g/kg/day in females, and 2.12 g/kg/day in males and 2.42 g/kg/day in females, respectively...
  100. ncbi Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis
    A G Schapowal
    Hochgebirgsklinik Davos Wolfgang, Switzerland
    Acta Otorhinolaryngol Belg 49:235-50. 1995
    ..There is an intolerance to aspirin and most other NSAID. An intolerance to tartrazine, food additives, alcohol, narcotics and local anaesthetics can follow. Most aspirin-sensitive patients develop nasal polyps...
  101. ncbi Overview of inhalation exposure techniques: strengths and weaknesses
    Jürgen Pauluhn
    Department of Toxicology, Institute of Toxicology, Bayer AG, Healthcare, Building No 514, 42096 Wuppertal, Germany
    Exp Toxicol Pathol 57:111-28. 2005
    ..waste sites, drinking water disinfection by-products, natural flavoring complexes or the cumulative intake of food additives and pesticide residues, the scientific evaluation of complex airborne mixtures, such as acid aerosols, ..

Research Grants51

  1. Modulation of Oxidative Damage by Tea Polyphenols
    Jia Sheng Wang; Fiscal Year: 2002
    ..The results of this proposed study will help to understand the mechanisms of antioxidative role of tea polyphenols in modulating human hepatocarcinogenesis caused by hepatitis B/C viruses and aflatoxins. ..
  2. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2012
    ..to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, food, or water...
  3. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2011
    ..to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, food, or water...
  4. SUPPORT CONTRACT FOR THE NTP INTERAGENCY CENTER/VALIDATION OF ALT METHODS
    David Allen; Fiscal Year: 2009
    ..to substances such as pesticides, consumer products, medicines, medical devices, workplace chemicals, food additives, or to contaminants in air, food, or water...
  5. Phosphorus-based Food Additives, Mineral Metabolism and Cardiovascular Health
    ORLANDO M GUTIERREZ; Fiscal Year: 2013
    ..recommendations for daily intake, in large part due to the nearly ubiquitous distribution of phosphorus-based food additives in the US food supply...
  6. What a Difference an X Makes: The State of Women's Health
    Christine Carter; Fiscal Year: 2013
    ..the management of chronic diseases in women;4) Nutrition and Obesity: Panelists will address the role of diet, food additives and obesity in chronic diseases...
  7. Role of Nrf2 in immunotoxicity by food additives and environmental contaminants
    CHERYL ELIZABETH ROCKWELL; Fiscal Year: 2013
    ..abstract_text> ..
  8. Nasal dosimetry of diacetyl and butyric acid vapors
    John Morris; Fiscal Year: 2005
    ..Although generally recognized as safe as food additives, exposure of workers to these vapors is associated with bronchiolitis obliterans...
  9. Predictive Genes Sets For Chemically-Induced Liver Cancer
    BRIAN A NAUGHTON; Fiscal Year: 2010
    ..potential of untested chemicals and allow a significant savings of time, money and animals for both governmental agencies as well as private industry related to chemical manufacturing, food additives and pharmaceuticals.
  10. Workshop on Measurement Methods for Release of Engineered Nanomaterials from Food
    Richard Canady; Fiscal Year: 2012
    ..quantify engineered nanoparticles released from food along the alimentary tract, as occurring through direct food additives or indirect incorporation in food through migration from food packaging or environmental contamination...
  11. NEW CATALYSTS FOR ASYMMETRIC DIELS-ALDER REACTIONS
    Peter Mackenzie; Fiscal Year: 1991
    ..stereochemistry is therefore frequently essential in the synthesis of a number of important pharmaceuticals, food additives and pheromones...
  12. OBESITY: ROLE OF EMOTIONS AND LEVEL OF REINFORCEMENT
    Edwin Fisher; Fiscal Year: 1980
    ..Participants will be told we are studying the effects of food additives on mood...
  13. TOXICOLOGY OF BROMINATED FATTY ACIDS
    IAN TINSLEY; Fiscal Year: 1980
    ..Initial studies will concentrate on brominated fatty acids because of their use in food additives and flame retardants and their occurrence in marine oils...
  14. An In Vitro Robotic Assay for Anti-Estrogenic Activity
    CATHY YANG; Fiscal Year: 2006
    ..investigations have shown that many chemicals used in plastics, Pharmaceuticals, pesticides, cosmetics, food additives, etc., are endocrine disrupters (EDs)...
  15. In Vitro Robotic Assay for Estrogenic Activity
    CATHY YANG; Fiscal Year: 2005
    ..investigations have shown that many chemicals used in plastics, pharmaceuticals, )esticides, cosmetics, food additives, etc. are endocrine disruptors (EDs)...
  16. An In Vitro Robotic Assay for Estrogenic Activity
    CATHY YANG; Fiscal Year: 2002
    ..investigations have shown that many chemicals used in plastics, pharmaceuticals, pesticides, cosmetics, food additives, etc...
  17. INTERACTION OF DRUGS & FOOD ADDITIVES WITH VITAMIN A
    Charles Lieber; Fiscal Year: 1990
    ..to recognize conditions that result in vitamin A depletion in association with the use and abuse of drugs and food additives 2) to determine to what extent liver damage may ensue and 3) to define the "therapeutic window" that pertains ..
  18. ABSOLUTE STEREOCONTROL VIA 2-ALKENYL-1,3-DIOXOLANONES
    Peter Mackenzie; Fiscal Year: 1991
    The absolute control of stereochemistry is frequently essential in the synthesis of important pharmaceuticals, food additives and pheromones...
  19. BIOSTATISTICAL METHODS FOR CARCINOGENICITY EXPERIMENTS
    Stephen Lagakos; Fiscal Year: 1990
    ..research into problems arising in laboratory experiments designed to assess the potential hazards of food additives, drugs, cosmetics, and other chemicals...
  20. NITROGENOUS LIGANDS AND HEPATIC MONOOXYGENASES
    HOWARD SHERTZER; Fiscal Year: 1980
    ..would be important since man is exposed to many of these nitrogenous compounds in the form of air pollutants, food additives and drugs...
  21. XANTHOPHYLL BIOSYNTHESIS IN BACTERIA
    DENNIS GIERHART; Fiscal Year: 1991
    ..If these studies continue to be confirmed, carotenoids may increasingly be considered valuable food additives, as well as chemotherapeutic agents in the prevention and treatment of cancer...
  22. CELLULAR FATTY ACIDS FOR MONITORING COLONIC MICROFLORA
    ROBERT CARMAN; Fiscal Year: 1993
    Non-nutritive food additives and antibiotics are entering the food chain in ever increasing amounts. Consequently, there is increased public health concerns over the effects these compounds may have on the human intestinal microflora...
  23. Development of a New High-Throughout Mammalian DEL Assay
    Richard Brennan; Fiscal Year: 2001
    ..is playing an increasing role in the early development of pharmaceuticals, cosmetics, chemicals, and food additives. There is a continuing need for high-throughput genetic toxicology assays more predictive of carcinogenicity ..
  24. MODEL FOR IDENTIFICATION OF GENETIC LESIONS
    Jay Short; Fiscal Year: 1991
    ..The increases concerns of human composure to mutagenic compounds from such common sources as drinking water, food additives and industrial materials outlines the importance of proper mutagen assessment...
  25. DIETARY CONSTITUENT CANCER MODULATION ANALYSIS SYSTEM
    Barbara Petersen; Fiscal Year: 1992
    ..results, (2) databases providing information on the levels of food constituents (nutrients, contaminants, food additives, and other components of food), and (3) biological characteristics of food constituents (recommended intake ..
  26. IDENTIFICATION OF GENETIC LESIONS LEADING TO MUTATIONS
    Jay Short; Fiscal Year: 1990
    ..The increased concerns of human exposure to mutagenic compounds from such common sources as drinking water, food additives and industrial materials outlines the importance of proper mutagen assessment...
  27. ALCOHOL APPETITE--A NUTRIENT CONDITIONING ANALYSIS
    Karen Ackroff; Fiscal Year: 2001
    ..It will advance our basic knowledge of the psychobiology of alcohol appetite and may provide practical benefits for controlling alcohol consumption in humans. ..
  28. A device containing immobilized chelator to remove aluminum from TPN solutions
    Robert Yokel; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  29. Aluminum bioavailability from foods
    Robert Yokel; Fiscal Year: 2004
    ..abstract_text> ..
  30. COMBINING A SMOKE ENDING AID WITH BEHAVIORAL TREATMENT
    Peter Gariti; Fiscal Year: 2001
    ..The findings of this study will provide sufficient evidence for the efficacy of the experimental treatment and its extended investigation in a Phase II study or for its nonefficacy. ..
  31. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  32. Ethanol & Anxiety: Cellular Mechanisms
    BRIAN MCCOOL; Fiscal Year: 2008
    ..These studies could therefore provide insight into the cellular mechanisms governing anxietyassociated relapse in human alcoholics. ..
  33. Determination of RDA for Vitamin D in Caucasian and African American Women
    John Gallagher; Fiscal Year: 2009
    ..The results from this study will also help in designing future larger clinical trials of the effect of vitamin D on falls and fractures. ..
  34. METHYLPHENIDATE STUDY IN YOUNG CHILDREN WITH PDD
    Jaswinder Ghuman; Fiscal Year: 2005
    ..The proposed training program will allow the candidate to acquire sufficient expertise to carry out future treatment intervention studies in a very specialized area. ..
  35. EARLY HUSBANDRY INFLUENCES ON ADULT PHENOTYPE
    MICHAEL TORDOFF; Fiscal Year: 2009
    ..The results will lead to better environmental controls in future work and, asa direct consequence, easierand more rapid progress with genetic analyses. ..
  36. Developmental Neurotoxicity of Phthalate Esters
    Bernard Weiss; Fiscal Year: 2008
    ..The proposed research will examine this question in rats, and translate its implications into human relevance. [unreadable] [unreadable] [unreadable]..
  37. ACTIONS OF OPIATE DRUGS--DIETARY MODULATION
    ROBIN KANAREK; Fiscal Year: 2002
    ....
  38. Pimecrolius on T cell Responses in Atopic March
    Jonathan Spergel; Fiscal Year: 2008
    ..In third aim of the trial, we explore the effects of pimecrolimus as a disease-modifying agent in the prevention of asthma. Asthma phenotype will be examined by spirometry per and post-beta-2-agonist and exhaled nitric oxide. ..
  39. A new method to measure taste bud function
    Stephen Roper; Fiscal Year: 2004
    ..If these cells turn out to be mechanoreceptors, the results may explain how taste buds detect food texture. This will greatly further our understanding of food selection and diet. ..
  40. Neurotoxic Interactions of Different Forms of Mercury
    Bernard Weiss; Fiscal Year: 2007
    ..The acquisition of these data offers a firm foundation for determining the risks to neurobehavioral development of concurrent exposures to both mercury species. ..
  41. Light Smoking Program
    Peter Gariti; Fiscal Year: 2007
    ..g., withdrawal symptoms, adverse events, weight gain, treatment satisfaction) characteristics of the participants are predictive of treatment response. ..
  42. GABA-A Receptors, Ethanol, and Stress in Monkey Amygdala
    BRIAN MCCOOL; Fiscal Year: 2006
    ..Ultimately, our proposed studies will help lead to a better understanding of the ethanol-anxiety/stress interaction in primates. ..
  43. Role of Genomic Imprinting in Developmental Neurotoxici*
    Ellen Silbergeld; Fiscal Year: 2003
    ..2. To utilize high throughput methods to examine patterns of DNA methylation in candidate genes in sperm and zygote in order to detect the presence of male-mediated effects on imprinted genes involved in early development. ..
  44. Transdisciplinary Research on Urban Health Collaborative (RMI)
    Nicholas Freudenberg; Fiscal Year: 2008
    ..This application will provide support for the institutionalization of these efforts at the University that educates more researchers and professionals involved in urban health than any university in the nation. [unreadable] [unreadable]..
  45. Nutritional/Inflammatory Evaluation of Dialysis Patients
    Kamyar Kalantar Zadeh; Fiscal Year: 2005
    ....
  46. Colon and liver anticarcinogenicity by acetaminophen
    Gary Williams; Fiscal Year: 2004
    ..In addition, these experiments will provide support for the epidemiological observations of reduced cancer risk associated with the use of APAP. ..
  47. Impact/HIV Intervention/Adolescent Males Leaving Jail
    Nicholas Freudenberg; Fiscal Year: 2005
    ..This sub-study will also be used to tailor the intervention tested in this proposal for adolescent females. ..
  48. Anti-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients
    Kamyar Kalantar Zadeh; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  49. Genetic Susceptibility to Mercury-Induced Immune Dysfunction in Autism & ASD
    Ellen Silbergeld; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..