Summary: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Publications280 found, 100 shown here
- A gas chromatography-mass spectrometric method to determine skin-whitening agents in cosmetic productsAlberto Chisvert
Departamento de Quimica Analitica, Facultad de Quimica, Universidad de Valencia, Doctor Moliner Street, 50, 46100 Burjassot, Valencia, Spain
Talanta 81:530-6. 2010..kojic acid, azelaic acid and arbutin) and two forbidden (resorcinol and hydroquinone) skin-whitening agents in cosmetics. The method is based on gas chromatography coupled with mass spectrometric detection, which allows the two ..
- Endocrine disruptors and asthma-associated chemicals in consumer productsRobin E Dodson
Silent Spring Institute, Newton, Massachusetts 02458, USA
Environ Health Perspect 120:935-43. 2012..Laboratory and human studies raise concerns about endocrine disruption and asthma resulting from exposure to chemicals in consumer products. Limited labeling or testing information is available to evaluate products as exposure sources...
- From miso, saké and shoyu to cosmetics: a century of science for kojic acidRonald Bentley
Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
Nat Prod Rep 23:1046-62. 2006..It was one of the first secondary metabolites to have its biosynthetic pathway studied by the isotope tracer technique, and, more recently, has been of interest as a skin lightening agent. There are 112 references...
- Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmeticsShinya Kato
Laboratory of Cell Death Control BioTechnology, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 562, Nanatsuka, Shobara, Hiroshima 727 0023, Japan
J Nanosci Nanotechnol 10:6769-74. 2010..We suggest that LF-SQ could be used as an active ingredient for wrinkle-care cosmetics.
- Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010Sarah Adler
Centre for Documentation and Evaluation of Alternatives to Animal Experiments ZEBET, Federal Institute for Risk Assessment BfR, Berlin, Germany
Arch Toxicol 85:367-485. 2011The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics on the market in Europe after 2013...
- Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, PakistanArshad Mehmood Abbasi
Department of Plant Sciences, Quaid i Azam University, Islamabad 45320, Pakistan
J Ethnopharmacol 128:322-35. 2010The present investigation is an attempt to find out ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics.
- Assessment of lead in cosmetic productsIman Al-Saleh
Environmental Health Section, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, P O Box 3354, Riyadh 11211, Saudi Arabia
Regul Toxicol Pharmacol 54:105-13. 2009..This has drawn our attention to assess the safety of various cheap brands of cosmetics sold at 2-riyals stores in Saudi market that are imported from countries where safety regulations are poorly ..
- Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: correlation of UV filters with use of cosmeticsMargret Schlumpf
GREEN Tox and Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
Chemosphere 81:1171-83. 2010..Our data emphasize the need for analyses of complex mixtures to obtain more information on inter-individual and temporal variability of human exposure to different types of chemicals...
- Determination of total lead in lipstick: development and validation of a microwave-assisted digestion, inductively coupled plasma-mass spectrometric methodNancy M Hepp
Office of Cosmetics and Colors, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, MD 20740, USA
J Cosmet Sci 60:405-14. 2009..This method will be useful for the FDA and industry in helping to ensure the safety of cosmetic products...
- Optical characteristics of titanium oxide interference film and the film laminated with oxides and their applications for cosmeticsTakahiro Kaida
Nihon Koken Kogyo Company, Ltd, Tachikawa shi, Japan
J Cosmet Sci 55:219-20. 2004
- Categorization framework to aid exposure assessment of nanomaterials in consumer productsSteffen Foss Hansen
Department of Environmental Engineering, NanoDTU Environment and Health, Technical University of Denmark, DTU Building 113, Kgs Lyngby 2800, Denmark
Ecotoxicology 17:438-47. 2008..The application of sun lotion containing 2% nanoparticles result in an exposure of 56.7 mg kg(-1) bw d(-1) for a 2-year-old child, if the amounts applied correspond to the European Commission recommendations on use of sunscreen...
- Novel cosmetic delivery systems: an application updateV B Patravale
Department of Pharmaceutical Sciences and Technology, University Institute of Chemical Technology, Mumbai 400 019, India
Int J Cosmet Sci 30:19-33. 2008..Functional ingredients and innovative delivery systems are driving the new product development in the field of cosmetics. A significant number of innovative formulations are now being used in personal care with real consumer-..
- European consumer exposure to cosmetic products, a framework for conducting population exposure assessments Part 2B Hall
L Oreal, Worldwide Safety Evaluation, Asnières sur Seine, France
Food Chem Toxicol 49:408-22. 2011..date and largely confirm the current exposure parameters concerning some 95% of the estimated daily exposure to cosmetics use in the EU...
- Recent progresses in application of fullerenes in cosmeticsMarko Lens
King s College, St Thomas s Hospital, Westminster Bridge Road, London SE1 7EH, UK
Recent Pat Biotechnol 5:67-73. 2011..Published evidence on biological activities of fullerenes relevant for their application in cosmetics use and examples of published patents are presented...
- Spectroscopic detection of health hazardous contaminants in lipstick using Laser Induced Breakdown SpectroscopyM A Gondal
Physics Department and Center of Excellence in Nanotechnology, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
J Hazard Mater 175:726-32. 2010..For this purpose, special treatment of the lipstick samples was necessary to analyze with our LIBS method...
- Concentrations and potential health risks of metals in lip productsSa Liu
Environmental Health Sciences Division, School of Public Health, University of California, Berkeley, Berkeley, California 94720 7360, USA
Environ Health Perspect 121:705-10. 2013..Metal content in lip products has been an issue of concern...
- European consumer exposure to cosmetic products, a framework for conducting population exposure assessmentsB Hall
L Oreal, Worldwide Safety Evaluation, River Plaza 25 29 quai Aulagnier, 92600 Asnières sur Seine, France
Food Chem Toxicol 45:2097-108. 2007..The results largely confirm the exposure parameters currently used by the cosmetic industry. Design of this study could serve as a model for future assessments of population exposure to chemicals in products other than cosmetics.
- Accumulation of mercury in ovaries of mice after the application of skin-lightening creamsIman Al-Saleh
Biological and Medical Research Department, King Faisal Specialist Hospital, Riyadh, Saudi Arabia
Biol Trace Elem Res 131:43-54. 2009..Alternatively, public health authorities should encourage more reliance on prescribed creams for the treatment of skin pigmentation problems...
- Investigation of lead contents in lipsticks by solid sampling high resolution continuum source electrothermal atomic absorption spectrometrySema Gunduz
Istanbul Technical University, Faculty of Science and Letters, Department of Chemistry, 34469 Maslak Istanbul, Turkey
Regul Toxicol Pharmacol 65:34-7. 2013..The lead in 25 lipstick samples with different properties were 0.11-4.48 ng mg(-1) which were not significantly different from those (<0.026-7.19 ng mg(-1)) reported by FDA for around 400 samples...
- Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methodsMarcel Leist
Centre for Alternatives to Animal Testing, CAAT Europe, University of Konstanz, Germany
ALTEX 29:373-88. 2012..The overall hazard and risk assessment strategy integrating these different examples has been compiled in a graphical work flow...
- Usage patterns of personal care products: important factors for exposure assessmentJacqueline W H Biesterbos
Radboud University Medical Centre, Department for Health Evidence, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Food Chem Toxicol 55:8-17. 2013..As expected, the participants used several PCPs simultaneously. The database yields important personalized exposure factors which can be used in aggregate consumer exposure assessment for substances that are components of PCPs...
- Metabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytesP Tucci
Medical Research Council, Toxicology Unit, Leicester University, Leicester, UK
Cell Death Dis 4:e549. 2013..No other morphological changes were detected after 24-h exposure consistent with a specific role of mitochondria in this response...
- Potential exposure of German consumers to engineered nanoparticles in cosmetics and personal care productsChristiane Lorenz
Institute for Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland
Nanotoxicology 5:12-29. 2011..Along with toxicological data, exposure estimates are essential for assessing risk. Currently, cosmetics and personal care products (C&PCP) represent the largest ENP-containing consumer product class on the market...
- Toxicological profile of diethyl phthalate: a vehicle for fragrance and cosmetic ingredientsA M Api
Research Institute for Fragrance Materials Inc, Two University Plaza, Suite 406, Hackensack, NJ 07601, USA
Food Chem Toxicol 39:97-108. 2001..75 mg/kg/day oral exposure) indicates no significant toxic liability for the use of DEP in fragrances and cosmetic products...
- Formulation and in vitro evaluation of a cosmetic emulsion from almond oilNaveed Akhtar
Faculty of Pharmacy and Alternative Medicine, Department of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Pak J Pharm Sci 21:430-7. 2008....
- Development of the EpiOcular(TM) eye irritation test for hazard identification and labelling of eye irritating chemicals in response to the requirements of the EU cosmetics directive and REACH legislationYulia Kaluzhny
MatTek Corporation, Ashland, MA 01721, USA
Altern Lab Anim 39:339-64. 2011The recently implemented 7th Amendment to the EU Cosmetics Directive and the EU REACH legislation have heightened the need for in vitro ocular test methods...
- Usage pattern of personal care products in California householdsXiangmei May Wu
Department of Public Health Sciences, University of California, Davis, CA 95616, USA
Food Chem Toxicol 48:3109-19. 2010..This information will be valuable for exposure and risk assessments...
- Structural degradation at the surface of a TiO(2)-based nanomaterial used in cosmeticsMelanie Auffan
CEREGE UMR 6635 CNRS Aix Marseille Universite, Europole de l Arbois, Aix en Provence, France
Environ Sci Technol 44:2689-94. 2010..We focused here on a hydrophobic TiO(2) nanoparticle-based formulation used in cosmetics: T-Lite SF...
- Exposure data for cosmetic products: lipstick, body lotion, and face creamL J Loretz
Cosmetic, Toiletry, and Fragrance Association, 1101 17th Street NW, Suite 300, Washington, DC 20036, USA
Food Chem Toxicol 43:279-91. 2005..The effect of product preference on use practices was also investigated. This study provides current cosmetic exposure information for commonly used products which will be useful for risk assessment purposes...
- Engineered inorganic nanoparticles and cosmetics: facts, issues, knowledge gaps and challengesJohann W Wiechers
Independent Consultant for Cosmetic Science, JW Solutions, Gasthuispolderweg 30, 2807 LL Gouda, The Netherlands
J Biomed Nanotechnol 6:408-31. 2010..concerning the safety and environmental impact of ENPs used in cosmetics. This review paper seeks to address the twin concerns of the safety of cosmetics and the potential environmental ..
- Ultrasound-assisted emulsification of cosmetic samples prior to elemental analysis by different atomic spectrometric techniquesI Lavilla
Departamento de Quimica Analitica y Alimentaria, Area de Quimica Analitica, Facultad de Quimica, Universidad de Vigo, As Lagoas Marcosende s n, 36310 Vigo, Spain
Talanta 80:109-16. 2009..Microwave-assisted digestion and Inductively Coupled Plasma Mass Spectrometry were used for comparison purposes. Relative standard deviations from analysis of five independent emulsions were less than 9% in all cases...
- Safety assessment of personal care products/cosmetics and their ingredientsGerhard J Nohynek
L Oreal R and D, Global Safety Evaluation, 92600 Asnières, France
Toxicol Appl Pharmacol 243:239-59. 2010..In the interest of all stakeholders, consumers, regulatory bodies and producers, there is an urgent need for an international harmonization on the status and safety requirements of these products and their ingredients...
- Silver nanoparticles as a safe preservative for use in cosmeticsSatoshi Kokura
Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Nanomedicine 6:570-4. 2010..These results suggest that Ag nanoparticles may have potential for use as a preservative in cosmetics. From the clinical editor: In this study, the effects of recently synthesized Ag nanoparticles were investigated ..
- Lip colour affects perceived sex typicality and attractiveness of human facesIan D Stephen
Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK
Perception 39:1104-10. 2010..The association between lip colour contrast and attractiveness in women's faces may be attributable to its association with oxygenated blood perfusion indicating oestrogen levels, sexual arousal, and cardiac and respiratory health...
- Lead and traditional Moroccan pharmacopoeiaN Lekouch
University Cadi Ayyad, Faculty of Sciences, Department of Biology, Marrakech, Morocco
Sci Total Environ 280:39-43. 2001The use of traditional cosmetics and remedies such as kohl and henna is very common in Morocco, especially among women, children and babies. Kohl is a dangerous eye cosmetic...
- Decorative cosmetics improve the quality of life in patients with disfiguring skin diseasesWolf Henning Boehncke
Department of Dermatology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590, Frankfurt Main, Germany
Eur J Dermatol 12:577-80. 2002..We therefore asked whether the application of decorative cosmetics might increase their quality of life...
- Mercury poisoning associated with a Mexican beauty creamM M Weldon
Epidemic Intelligence Service EIS Epidemiology Program Office, CDC Atlanta, GA, USA
West J Med 173:15-8; discussion 19. 2000....
- Objective evaluation of the efficacy of daily topical applications of cosmetics bases using the hairless mouse model of atopic dermatitisKatsuo Matsumoto
POLA Laboratories, Kashio cho, Totsuka ku, Yokohama, Kanagawa, Japan
Skin Res Technol 11:209-17. 2005..To elucidate the mechanisms underlying the clinical effectiveness of these newer treatments, we used our recently established hairless mouse model of AD...
- Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirantLinda Loretz
Cosmetic, Toiletry, and Fragrance Association, 1101 17th Street NW, Suite 300, Washington, DC 20036, USA
Food Chem Toxicol 44:2008-18. 2006..Six widely used personal care product types were included in the studies. Five of the products were cosmetics (spray perfume, hairspray, liquid foundation, shampoo, body wash) and one product was a cosmetic/over-the-..
- Efficacy of lanolin and bovine type I collagen in the treatment of childhood anal fissures: a prospective, randomized, controlled clinical trialBehçet Ilker Büyükyavuz
Department of Pediatric Surgery, Suleyman Demirel University Medical School, 32260, Isparta, Turkey
Surg Today 40:752-6. 2010..We designed an open-labeled, prospective, randomized, controlled clinical trial to test the efficacy of topical lanolin ointment (PureLan) and bovine type I collagen spray (Gelfix) in the treatment of childhood anal fissures...
- Study of sensory properties of emollients used in cosmetics and their correlation with physicochemical propertiesMaria Emma Parente
Cátedra de Química Cosmética, Facultad de Quimica, Universidad de la Republica, Montevideo, Uruguay
J Cosmet Sci 56:175-82. 2005..PLS revealed that emollient sensory attributes could be well predicted by instrumental measurements...
- Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredientsR Kroes
Institute for Risk Assessment Sciences, Utrecht University, c o Seminariehof 38, NL 3768 EE Soest, The Netherlands
Food Chem Toxicol 45:2533-62. 2007..Overall the TTC approach provides a useful additional tool for the safety evaluation of cosmetic ingredients and impurities of known chemical structure in the absence of chemical-specific toxicology data...
- Formaldehyde-releasers in cosmetics in the USA and in EuropeAnton C de Groot
Schipslootweg 5, 8351 HV Wapserveen, The Netherlands
Contact Dermatitis 62:221-4. 2010Frequencies of sensitization to formaldehyde among US patients patch tested for suspected contact dermatitis are higher than in Europe. Cosmetics are an important source of contact with formaldehyde.
- [Improvement of local lymph node assay for cosmetics safety evaluation]Zhen Liu
Department of Toxicology, The Second Military Medicine University, Shanghai 200433, China
Wei Sheng Yan Jiu 38:585-9. 2009..To improve the local lymph node assay (LLNA) as an alternative method to detect chemicals for both sensitization and irritation...
- Safety of botanical ingredients in personal care products/cosmeticsEric Antignac
L Oreal Research and Innovation, Global Safety Evaluation, Asnières, France
Food Chem Toxicol 49:324-41. 2011..Pragmatic approaches for quality and safety standards of botanical ingredients are needed; consumer safety should be the first objective of conventional and botanical PCP ingredients...
- Lipopeptides in cosmeticsM Kanlayavattanakul
School of Cosmetic Science, Mae Fah Luang University, Chiangrai, Thailand
Int J Cosmet Sci 32:1-8. 2010Lipopeptides are biosurfactants extensively used in cosmetics. The consumption of cosmetics containing lipopeptides is increasing as a result of the exceptional surface properties and diverse biological activities of lipopeptides which ..
- Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmeticsCheng Hui Lin
Department of Biological Engineering, Yung Ta Institute of Technology, Pingtung, Taiwan
Anal Chim Acta 581:102-7. 2007..the contents of ascorbyl glucoside (AA-2G), kojic acid (KA), and niacinamide (VitB(3)) in commercial bleaching cosmetics. Our results indicate that AA-2G, KA, and VitB(3) separated well within 4...
- Frequency of dermatoses associated with cosmeticsIda Duarte
Sector of Allergy and Phototherapy, Clinic of Dermatology, Santa Casa de Sao Paulo Hospital and School of Medicine, Sao Paulo, Brazil
Contact Dermatitis 56:211-3. 2007The objectives of this study were (i) to determine the frequency of dermatoses caused by use of cosmetics in patients with specific complaints of reaction to cosmetic products, and (ii) to observe the main skin conditions frequently ..
- Hydrolysed wheat proteins present in cosmetics can induce immediate hypersensitivitiesMichel Lauriere
UMR INRA INA PG de Chimie Biologique, Centre de Recherche de Grignon, 78850 Thiverval Grignon, France
Contact Dermatitis 54:283-9. 2006b>Cosmetics containing hydrolysed wheat proteins (HWP) can induce rare but severe allergic reactions. 9 patients, all females without common wheat allergy, but with contact urticaria to such cosmetics, were studied...
- Use of the Reviscometer for measuring cosmetics-induced skin surface effectsM Paye
Colgate Palmolive R and D, Milmort, Belgium
Skin Res Technol 13:343-9. 2007..The Reviscometer RVM600 that measures resonance running time (RRT) has been shown to be inversely related to the skin stiffness. However, very few publications describe the use of this instrument for testing the effect of cosmetic products...
- Chemiluminescence determination of ferulic acid by flow-injection analysis using cerium(IV) sensitized by rhodamine 6GJu Peng Wang
School of Chemistry and Chemical Engineering, Chongqing Municipal Key Laboratory of Luminescence and Real Time Analysis, Southwest University, Chongqing 400715, PR China
Spectrochim Acta A Mol Biomol Spectrosc 71:204-8. 2008..The relative standard deviation was 2.4% for 10 replicate analyses of 1.0 x 10(-5) mol l(-1) ferulic acid. The proposed method was applied to the determination of ferulic acid in Taita Beauty Essence samples with satisfactory results...
- Simultaneous determination of heavy metals in cosmetic productsSo Mi Lee
Amore Pacific Corporation, 314 1 Bora dong, Giheung gu, Yongin si, Gyeonggi Do, 446 729, Republic of Korea
J Cosmet Sci 59:441-8. 2008..The new method was applied to analyze the amount of heavy metals contained in 22 cosmetic products and 11 coloring agents...
- Cosmetics Europe multi-laboratory pre-validation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritationN Alepee
L Oreal Research and Innovation, Aulnay sous Bois, France
Toxicol In Vitro 27:1476-88. 2013b>Cosmetics Europe, The Personal Care Association, known as Colipa before 2012, conducted a program of technology transfer and assessment of Within/Between Laboratory (WLV/BLV) reproducibility of the SkinEthic™ Reconstituted Human ..
- An expert consortium review of the EC-commissioned report "alternative (Non-Animal) methods for cosmetics testing: current status and future prospects - 2010"Thomas Hartung
Johns Hopkins University, Bloomberg School of Public Health, Center for Alternatives to Animal Testing, Baltimore, MD 21205, USA
ALTEX 28:183-209. 2011The European cosmetics legislation foresees a review in 2011 and possible postponement of the 2013 marketing ban to enforce the testing ban for systemic and repeated-dose animal tests...
- Evaluating beauty care provided by the hospital to women suffering from breast cancer: qualitative aspectsPhilippe Amiel
Institut de Cancerologie Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif Cedex, France
Support Care Cancer 17:839-45. 2009....
- Analysis of aliphatic dicarboxylic acids in pharmaceuticals and cosmetics by liquid chromatography (HPLC) with fluorescence detectionR Gatti
Department of Pharmaceutical Sciences, University of Bologna, Italy
J Pharm Biomed Anal 13:589-95. 1995..The proposed methods proved to be suitable for the quality control of various complex pharmaceutical and cosmetic formulations of the azelaic acid and meglutol...
- Aromatase inhibiting and combined estrogenic effects of parabens and estrogenic effects of other additives in cosmeticsJ A van Meeuwen
Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
Toxicol Appl Pharmacol 230:372-82. 2008..Our calculation for the extra estrogen burden due to exposure to parabens, phthalates and polycyclic musks indicates an insignificant estrogenic load relative to the endogenous or therapeutic estrogen burden...
- [Medical corrective make-up in post- chemotherapy]C Merial-Kieny
Laboratoires Dermatologiques Avène Les Cauquillous, 81506 Lavaur cedex, France
Ann Dermatol Venereol . 2008..The aim of this study was to evaluate the tolerance and the satisfaction of patients needing medical make up to hide the cutaneous side effects induced by chimiotherapy and to improve self-esteem...
- Exposure data for cosmetic products: facial cleanser, hair conditioner, and eye shadowL J Loretz
Cosmetic, Toiletry, and Fragrance Association, Washington, DC 20036, USA
Food Chem Toxicol 46:1516-24. 2008..6, 1.1, and 1.2, respectively. This study provides an estimate of current exposure information for commonly used products which will be useful for risk assessment purposes...
- Synthetic musks in blood of healthy young adults: relationship to cosmetics useH P Hutter
Institute of Environmental Health, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15, A 1095, Vienna, Austria
Sci Total Environ 407:4821-5. 2009..Study participants also completed a questionnaire on the use of cosmetics, about nutrition and other life-style aspects...
- Refining aggregate exposure: example using parabensChristina E Cowan-Ellsberry
The Procter and Gamble Company, Cincinnati, OH, USA
Regul Toxicol Pharmacol 55:321-9. 2009..Comparison to the 95th percentile of these data showed that these refined estimates were still conservative by factors of 2-92. All of our refined estimates of aggregate exposure are less than the ADI of 10mg/kg/day for parabens...
- Patterns of cosmetic contact allergyMari Paz Castanedo-Tardan
Department of Medicine, Section of Dermatology, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
Dermatol Clin 27:265-80, vi. 2009..Once the offending allergen is identified, an avoidance regimen should be established to avoid further exposure...
- Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticalsCarmelo Puglia
University of Catania, Carmelo Puglia, Department of Drug Sciences, Faculty of Pharmacy, Catania, Italy
Expert Opin Drug Deliv 9:429-41. 2012..Solid lipid nanoparticles (SLN) and the newest nanostructured lipid carriers (NLC) show important advantages for dermal application of cosmetics and pharmaceuticals.
- Contact allergy to the 26 specific fragrance ingredients to be declared on cosmetic products in accordance with the EU cosmetics directiveMaria V Heisterberg
Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, National Allergy Research Centre, 2900 Hellerup, Denmark
Contact Dermatitis 65:266-75. 2011Fragrance ingredients are a frequent cause of allergic contact dermatitis. The EU Cosmetics Directive states that 26 specific fragrance ingredients, known to cause allergic contact dermatitis, must be declared on the ingredient lists of ..
- Cosmetics as a feature of the extended human phenotype: modulation of the perception of biologically important facial signalsNancy L Etcoff
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America
PLoS ONE 6:e25656. 2011..Here, we investigate one tool, the use of color cosmetics. In two studies, we asked viewers to rate the same female faces with or without color cosmetics, and we varied ..
- Molecularly imprinted layer-coated silica nanoparticles for selective solid-phase extraction of bisphenol A from chemical cleansing and cosmetics samplesRong Zhu
School of Pharmacy, Nanjing Medical University, Hanzhong Road 140, Nanjing, Jiangsu 210029, PR China
Anal Chim Acta 658:209-16. 2010..The BPA-imprinted silica nanoparticles were successfully used in SPE to selectively enrich and determine BPA from shampoo, bath lotion and cosmetic cream samples...
- Low molecular weight cyclic volatile methylsiloxanes in cosmetic products sold in Canada: implication for dermal exposureRong Wang
Exposure and Biomonitoring Division, Health Canada, Ottawa, ON, Canada
Environ Int 35:900-4. 2009Low molecular weight cyclic volatile methylsiloxane (cVMS) compounds have been used in a variety of cosmetics and personal care products and many other consumer products...
- Volatile pollutants emitted from selected liquid household productsKi Dong Kwon
Department of Indoor Environment, National Institute of Environment Research, Incheon, South Korea
Environ Sci Pollut Res Int 15:521-6. 2008..Consequently, the current study evaluated the emission composition for 42 liquid household products sold in Korea, focusing on five product classes (deodorizers, household cleaners, color removers, pesticides, and polishes)...
- Final report of the safety assessment of Kojic acid as used in cosmeticsChristina L Burnett
Cosmetic Ingredient Review, Washington, DC 20036, USA
Int J Toxicol 29:244S-73. 2010..available human sensitization data supported the safety of kojic acid at a use concentration of 2% in leave-on cosmetics. Kojic acid depigmented black guinea pig skin at a concentration of 4%, but this effect was not seen at 1%...
- Changes in European legislation make it timely to introduce a transparent market surveillance system for cosmeticsMarie Lodén
Research and Development, ACO HUD NORDIC AB, Upplands Vasby, Sweden
Acta Derm Venereol 87:485-92. 2007Marketing of cosmetics often makes strong claims linked to active ingredients...
- Carotenoids and polyphenols in nutricosmetics, nutraceuticals, and cosmeceuticalsTalita Pizza Anunciato
Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brasil
J Cosmet Dermatol 11:51-4. 2012..As a recent result of convergence phenomenon between cosmetics and food industries, nutricosmetics is a blurry area unfamiliar to many consumers and sometimes even to foods ..
- Colored facial cosmeticsZ D Draelos
Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Dermatol Clin 18:621-31. 2000Colored cosmetics are an important part of the dermatologic armamentarium...
- Consumer inhalation exposure to formaldehyde from the use of personal care products/cosmeticsMarc André Lefebvre
L Oreal, Research and Innovation, 25 29 quai Aulagnier, 92665 Asnières, France
Regul Toxicol Pharmacol 63:171-6. 2012..4-87 μg/m³). Overall, our data yielded evidence that inhalation of FA from the use of PCP containing FA-releasers poses no risk to human health...
- Mercury levels in locally manufactured Mexican skin-lightening creamsClaudia P Peregrino
Environmental Department, Advanced Material Research Center, Miguel de Cervantes 120, Chihuahua, Chih 31109, Mexico
Int J Environ Res Public Health 8:2516-23. 2011..Skin creams containing mercury are still available and commonly used in Mexico and many developing countries, and their contents are poorly controlled...
- Use of fullerenes in cosmeticsMarko Lens
King s College, Genetic Epidemiology Unit, St Thomas s Hospital, Lambeth Palace Road, London, UK
Recent Pat Biotechnol 3:118-23. 2009..In the last few years application of fullerene C(60) and its derivates in cosmetics has been intensively tested. Fullerenes display a wide range of biological activities...
- Are adverse skin reactions to cosmetics underestimated in the clinical assessment of contact dermatitis? A prospective study among 1075 patients attending Swedish patch test clinicsMagnus Lindberg
Department of Medicine, Occupational and Environmental Dermatology, Karolinska Institutet, Stockholm, Sweden
Acta Derm Venereol 84:291-5. 2004It is known that cosmetics and skin care products can cause adverse skin reactions. However, the frequency of adverse reactions reported to the Medical Product Agency (MPA) in Sweden is low...
- Use of topical herbal remedies and cosmetics: a questionnaire-based investigation in dermatology out-patientsM Corazza
Department of Clinical and Experimental Medicine, Section of Dermatology, University of Ferrara, Ferrara, Italy
J Eur Acad Dermatol Venereol 23:1298-303. 2009Although topical remedies and cosmetics based on herbal ingredients are becoming increasingly popular with the public due to the perception that botanical compounds are safer and healthier than their synthetic counterparts, a large ..
- Marinosomes, marine lipid-based liposomes: physical characterization and potential application in cosmeticsN Moussaoui
Laboratoire de Nutrition et Signalisation Cellulaire, ISTAB, Universite Bordeaux I, Avenue des Facultes, F 33405 Cedex, Talence, France
Int J Pharm 242:361-5. 2002..At low pH (pH 4) or in presence of high calcium concentrations (9 mM), complex structural rearrangements, such as aggregation and size reduction, occurred which were kinetically dependant...
- Validation of HPLC method for the simultaneous and quantitative determination of 12 UV-filters in cosmeticsM Nyeborg
Laboratoire COTY LANCASTER, Recherche et développement analytique, 6, avenue Albert II, 98000 Monaco, France
Int J Cosmet Sci 32:47-53. 2010..UV measurements were carried out at multi-wavelengths, according to the absorption of the analytes...
- Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyesD J Kirkland
Covance Laboratories Limited, Otley Road, Harrogate HG3 1PY, UK
Mutat Res 588:88-105. 2005The European Scientific Committee on Cosmetics and Non-Food Products (SCCNFP) guideline for testing of hair dyes for genotoxic/mutagenic/carcinogenic potential has been reviewed...
- Allergic contact dermatitis from cosmetics. Retrospective analysis of 819 patch-tested patientsL Kohl
Department of Dermatology, University Hospital St Pierre, Brussels, Belgium
Dermatology 204:334-7. 2002b>Cosmetics have been used since the oldest known civilisations, and nowadays almost everybody resorts to beauty products.
- Safety evaluation of cosmetics in the EU. Reality and challenges for the toxicologistMarleen Pauwels
Dermato Cosmetology and Pharmacognosy, Department of Toxicology, Vrije Universiteit Brussel, Laarbeeklaan 103, B 1090 Brussels, Belgium
Toxicol Lett 151:7-17. 2004..i) The full responsibility for the safety of cosmetics for human health is placed on the manufacturer, first importer in the EU or marketer...
- Rapid detection of ricin in cosmetics and elimination of artifacts associated with wheat lectinJacqueline Dayan-Kenigsberg
Unité Biotechnologie, Biochimie des Protéines et Macromolécules, agence française de sécurité sanitaire des produits de santé, 143 boulevard Anatole France, 93285 Saint Denis Cedex, France
J Immunol Methods 336:251-4. 2008Ricin can be detected in cosmetics at 0.005 microg/mL in the analytical sample using lateral flow devices (LFDs). Wheat germ, an ingredient used in skin care products is also a potential source of wheat lectin...
- A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysisStefan Pfuhler
Procter and Gamble, Miami Valley Laboratories, Cincinnati, OH 45253, USA
Regul Toxicol Pharmacol 57:315-24. 2010..Due to the 7th amendment to the EU Cosmetics Directive ban on in vivo genotoxicity testing for cosmetics that was enacted March 2009, it is no longer ..
- ECVAM's response to the changing political environment for alternatives: consequences of the European Union chemicals and cosmetics policiesThomas Hartung
ECVAM, Institute for Health and Consumer Protection, European Commission Joint Research Centre, 21020 Ispra VA, Italy
Altern Lab Anim 31:473-81. 2003..In essence, steering groups formed by ECVAM senior staff, and complemented with external experts, will carry out the project management and will coordinate the various inputs...
- Database search for safety information on cosmetic ingredientsMarleen Pauwels
Department of Toxicology, Dermato Cosmetology and Pharmacognosy, Vrije Universiteit Brussel, Laarbeeklaan 103, B 1090 Brussels, Belgium
Regul Toxicol Pharmacol 49:208-16. 2007..It should be mentioned that the search strategies described are equally useful as a starting point for any quest for safety data on chemicals or chemical-related substances in general...
- Methylisothiazolinone, an emerging allergen in cosmetics?Juan García-Gavín
Faculty of Medicine, Department of Dermatology, University of Santiago de Compostela, University Hospital Complex, Spain
Contact Dermatitis 63:96-101. 2010..In cosmetics, methylisothiazoline (MI) is permitted in a concentration of 100 p.p.m., while 15 p.p.m...
- Ethnobotany of medicinal plants used by Assamese people for various skin ailments and cosmeticsAbinash Pratim Saikia
Department of Biotechnology, Indian Institute of Technology Guwahati, North Guwahati 781039, Assam, India
J Ethnopharmacol 106:149-57. 2006..paper deals with the medicinal plants used by the people of Assam for curing different skin ailments and for cosmetics. A total of 85 plants belonging to 49 families have been documented for their therapeutic use against skin ..
- Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometryMaw Rong Lee
Department of Chemistry, National Chung Hsing University, Taichung 40227, Taiwan
J Chromatogr A 1120:244-51. 2006..Detection limits are achieved at the level of 4.7-142 ng/g. It was successfully applied to the determination of paraben preservatives and antioxidants in cosmetics without tedious pretreatment.
- Retinoids in cosmeceuticalsOlivier Sorg
Clinique de Dermatologie, Geneva University Hospital, Geneva, Switzerland
Dermatol Ther 19:289-96. 2006....
- A sex difference in facial contrast and its exaggeration by cosmeticsRichard Russell
Department of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA 02138, USA
Perception 38:1211-9. 2009..Application of cosmetics was found to consistently increase facial contrast...
- Applications of microemulsions in cosmeticsPrapaporn Boonme
Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Thailand
J Cosmet Dermatol 6:223-8. 2007..microemulsions were discovered approximately six decades ago, their applications in several fields, including cosmetics, have been increased due to their good appearance, thermodynamic stability, high solubilization power, and ease ..
- Complications of chronic use of skin lightening cosmeticsYetunde M Olumide
Dermatology Unit, Department of Medicine, College of Medicine, Lagos, Nigeria
Int J Dermatol 47:344-53. 2008Skin lightening (bleaching) cosmetics and toiletries are widely used in most African countries. The active ingredients in these cosmetic products are hydroquinone, mercury and corticosteroids...
- [Allergic contact dermatitis to cosmetics containing Melaleuca alternifolia (tea tree oil)]T M Fritz
Dermatologische Klinik, , Suisse
Ann Dermatol Venereol 128:123-6. 2001..DISCUSSION: The allergic potential of low concentrations of Melaleuca alternifolia is presumed to be low on healthy skin. Photoaged Melaleuca alternifolia must be considered to be a stronger sensitizer...
- Glucosides as unexpected allergens in cosmeticsA Goossens
Department of Dermatology, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium
Contact Dermatitis 48:164-6. 2003
- Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methodsHao Yu Shen
Analysis and Testing Center, Ningbo Institute of Technology, Zhejiang University, Ningbo, Zhejiang, PR China
J Sep Sci 30:48-54. 2007..The residue level is at 1.22-5289 mg/kg...
- Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literatureSarah Quartier
Department of Dermatology, University Hospital, Catholic University Leuven, B 3000 Leuven, Belgium
Contact Dermatitis 55:257-67. 2006..Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still unknown...
- Cosmetics in the treatment of acne vulgarisElla L Toombs
Aesthetic Dermatology of Dupont Circle, Washington, DC 20009, USA
Dermatol Clin 23:575-81, viii. 2005This article describes scenarios of patients who have acne vulgaris have tried over-the-counter products and cosmetics and are disheartened by the persistence of their disease and the resulting scars...
- Human health safety evaluation of cosmetics in the EU: a legally imposed challenge to scienceM Pauwels
Department of Toxicology, Dermato Cosmetology and Pharmacognosy, Vrije Universiteit Brussel VUB, Laarbeeklaan 103, B 1090 Brussels, Belgium
Toxicol Appl Pharmacol 243:260-74. 2010..substances, biocides, plant protection products, food additives, medicinal products, and of course also cosmetics. Horizontal legislative texts, on the contrary, cover more general fields such as protection of experimental ..
- A rapid and reliable size-exclusion chromatographic method for determination of kojic dipalmitate in skin-whitening cosmetic productsAngel Balaguer
Departamento de Quimica Analitica, Facultad de Quimica, Universidad de Valencia, 46100 Burjassot, Valencia, Spain
Talanta 75:407-11. 2008..The chromatographic run takes less than 8 min to complete. All these features make the method easy to apply to quality control in the cosmetic industry...
- Possible relation of Tunisian pemphigus with traditional cosmetics: a multicenter case-control studySylvie Bastuji-Garin
Department of Public Health, Hôpital Henri Mondor AP HP, Universite Paris XII, Creteil, France
Am J Epidemiol 155:249-56. 2002..factors were significantly associated with pemphigus in multivariate logistic regression analyses: traditional cosmetics (odds ratio (OR) = 4.0, 95% confidence interval (CI): 1.1, 14.8); Turkish baths (OR = 3.2, 95% CI: 1.4, 7...
- Investigating Mechanism of Intracellular Rotational Transport with Optical TJeffrey N Anker; Fiscal Year: 2012..With the increased use of engineered nanoparticles in medicine (diagnostics and therapeutics), electronics, cosmetics, and textiles and the corresponding awareness of the toxicity from such nanoparticles, there is a critical need ..
- Analyzer for Monitoring Personal Environmental Exposure to Fluids and MaterialsMATTHEW CUSACK; Fiscal Year: 2010..wine, coffee beer, tea) and all materials placed on the subject/patient's skin such as: lotions, perfumes, cosmetics (lipstick, makeup), soaps, shampoos, deodorant, etc...
- Absorption, distribution, metabolism, excretion (ADME) of chemicals in mammalsRochelle W Tyl; Fiscal Year: 2009..acid (butylparaben, BPB) is widely used as an antioxidant and preservative in foods, pharmaceuticals, and cosmetics. Human exposure can occur via inhalation, ingestion, or dermal contact...
- Field Validation of New XRF Analyzers: Assessing Personal Exposure to MetalsPATRICK JEREMY PARSONS; Fiscal Year: 2012..g., cosmetics, personal hygiene products) and matrices (e.g...
- HDAC Inhibitors Inspired by Natural ProductsDennis L Wright; Fiscal Year: 2012..valued for antibacterial and antiproliferative activity and are currently used in numerous topical agents and cosmetics. The composition of these extracts was studied in the early 1940s, leading to the identification of an unusual ..
- Structural and functional studies of botulinum neurotoxinRongsheng Jin; Fiscal Year: 2013..2001;Gill, 1982). Paradoxically, BoNT-containing medicines and cosmetics, such as Botox(R), Dysport(R), Xeomin(R), CBTXA(R), Myobloc(R) and NeuroBloc(R), have been used with great ..
- HEPylated G-CSF: Drug with Safer, Enhanced Delivery for Neutropenia TreatmentWei Jing; Fiscal Year: 2011..that are potentially being undermined by a plethora of PEG- containing consumer products including toothpaste, cosmetics, processed foods, and laxatives such that ~22-25% of the US population in 2001 (up from 0...
- eukaryotic expression vectors resistant to transgene silencingJames Williams; Fiscal Year: 2012..In Phase III the gene therapies for diabetic foot ulcers and skin cosmetics will undergo clinical development...
- Ear Canal Optical Coherent Tomography SystemPAUL SHNITSER; Fiscal Year: 2010..hearing aid candidates actually use these devices, owing to concerns about inconvenience, discomfort, stigma, cosmetics, sound quality, and affordability...
- A rapid label-free sensor for immune markers of environmental exposure for applicChristopher Striemer; Fiscal Year: 2012..The explosive growth of nanotechnology in research and consumer products (sunscreens, cosmetics, paint) is also creating an array of ultrafine materials with largely unknown health effects...
- Molecular Mechanisms of Obesity in Children Exposed to Phthalates in UteroNina T Holland; Fiscal Year: 2013..Evidence from animals and epidemiologic studies suggests that phthalates, components of plastics and cosmetics ubiquitously found in humans, may be obesogenic...
- XENOBIOTICS AND PRIMARY BILIARY CIRRHOSISMERRILL E GERSHWIN; Fiscal Year: 2013..on our functional data that autoimmune cholangitis can be induced by immunization of 2OA, a material found in cosmetics. In particular, we will define the role of effector mechanisms in this model that allows dissection of early ..
- Immunostimulatory properties of chitin and chitosanCHARLES ALLEN SPECHT; Fiscal Year: 2012..Chitin and/or chitosan are used in cosmetics and biomaterials, have been postulated to play a role in asthma, and have been proposed as vaccine adjuvants...
- Cytoxic and Genotoxic Effects of Manufactured Nanoparticles on Stem CellsYiling Hong; Fiscal Year: 2011..that are, or will be, prominently used in commercially available products: carbon NPs (car wax, fuel lines, cosmetics), silver NPs (antimicrobial wound dressings, odor-reducing socks), titanium dioxide NPs (sunscreens, paints), ..
- NITRIC OXIDE INHIBITOR AND LEISHMANIA PATHOGENESISMARION CHAN; Fiscal Year: 2004..Rural populations in India use turmeric abundantly in their daily life: as a spice, as a component of cosmetics, as an anti-inflammatory agent and other medications, and as a household topical remedy for minor injuries ..
- Impact of Environmental Pollutants on Breast Cancer and*Julia Brody; Fiscal Year: 2005..to EDCs and mammary carcinogens is common from sources such as air and water pollution, detergents, pesticides, cosmetics, plastics, building materials, and furnishings...
- NITRIC OXIDE INHIBITOR AND LEISHMANIA PATHOGENESISMARION CHAN; Fiscal Year: 2000..Rural populations in India use turmeric abundantly in their daily life: as a spice, as a component of cosmetics, as an anti-inflammatory agent and other medications, and as a household topical remedy for minor injuries ..
- Enhanced Phototoxicity Assay in Reconstituted SkinGEORGE DEGEORGE; Fiscal Year: 2002..The phototoxic potential of chemicals, cosmetics, dietary supplements and pharmaceuticals are a growing major concern in the consumer products industry...
- RIBONUCLEOSIDES FOR PREDICTION OF SKIN IRRITATIONWILLIAM REIFENRATH; Fiscal Year: 1999..PROPOSED COMMERCIAL APPLICATION Development of new materials that contact the skin (e.g. topical drugs, cosmetics) usually requires an assessment of skin irritation potential in an animal model...
- Nursing & Environmental Health Conference: Methymercury and Human Health EffectsJeanne Hewitt; Fiscal Year: 2006..communication by Hmong; a poster presentation session that illustrates traditional medicines, herbs, candies, cosmetics, and other products that can be sources of exposure to mercury, lead, and other toxins; a science experiment ..
- Tooth Phone Auditory Device TPADBARRY MERSKY; Fiscal Year: 2009..to the precedent device, the TPAD has many important advantages such as cost, safety, longevity, fidelity, and cosmetics. In the TPAD system, ambient speech and sound is picked-up by a microphone and radio transmitted to a removable ..
- MINORITY PREDOCTORAL FELLOWSHIP PROGRAMSHONDELLE WILSON; Fiscal Year: 2004..photo-oxidation of methane, oxidation of hydrocarbons released from plants and by numerous industrial products (cosmetics, cigarette smoke, automotive emissions, etc.); that contain this chemical as an ingredient...
- Phototoxicity Screening Assay in Reconstituted SkinGEORGE DEGEORGE; Fiscal Year: 2006..The phototoxic potential of chemicals, cosmetics, dietary supplements and Pharmaceuticals are a major and growing concern in the consumer products industry, but ..
- Mechanism of Thimerosal Induced NeurotoxicityKINSLEY KININGHAM; Fiscal Year: 2003..is a widely used ethyl mercury containing preservative used in over-the-counter medications, cleaners and cosmetics. Recent concern has been raised on the use of thimerosal in over 30 vaccines licensed in the United States...
- Nanoparticles and Arterial DiseaseVIRGINIA MILLER; Fiscal Year: 2009..Nanoparticles are being developed for such diverse industrial applications as data processing and cosmetics, and in medicine for targeted drug delivery, surface coatings to improve implantable devices and biosensors...
- NOVEL OLIGOPEPTIDES AS TOPICAL SKIN LIGHTENING AGENTSJAMES LEYDA; Fiscal Year: 2001..Additionally, the desire for skin whitening cosmetics is common in various cultures around the world...
- Neurotoxic Interactions of Different Forms of MercuryBernard Weiss; Fiscal Year: 2007..health risks are methylmercury, found in fish and marine mammals, and metallic mercury vapor, found in industry, cosmetics, and dental amalgams...
- Diethanolamine, brain development and adult memorySteven Zeisel; Fiscal Year: 2006..in the synthesis of fatty acid condensates that are present in many consumer products, including shampoos and cosmetics. DEA is structurally similar to choline, a methyl donor and an important endogenous precursor in the synthesis ..
- An In Vitro Robotic Assay for Anti-Estrogenic ActivityCATHY YANG; Fiscal Year: 2006..Recent scientific investigations have shown that many chemicals used in plastics, Pharmaceuticals, pesticides, cosmetics, food additives, etc., are endocrine disrupters (EDs)...
- In Vitro Robotic Assay for Estrogenic ActivityCATHY YANG; Fiscal Year: 2005Recent scientific investigations have shown that many chemicals used in plastics, pharmaceuticals, )esticides, cosmetics, food additives, etc. are endocrine disruptors (EDs)...
- An In Vitro Robotic Assay for Estrogenic ActivityCATHY YANG; Fiscal Year: 2002Recent scientific investigations have shown that many chemicals used in plastics, pharmaceuticals, pesticides, cosmetics, food additives, etc...
- BRAIN TUMORS AND N-NITROSO EXPOSURESBaruch Modan; Fiscal Year: 1992..The questionnaire asks about sources of NOC exposure such as diet, drugs, cosmetics, rubber products and parental occupational exposures...
- BIOSTATISTICAL METHODS FOR CARCINOGENICITY EXPERIMENTSStephen Lagakos; Fiscal Year: 1990..problems arising in laboratory experiments designed to assess the potential hazards of food additives, drugs, cosmetics, and other chemicals...
- Development of a New High-Throughout Mammalian DEL AssayRichard Brennan; Fiscal Year: 2001..by applicant) Molecular toxicology is playing an increasing role in the early development of pharmaceuticals, cosmetics, chemicals, and food additives...
- A Catalytic Conformational Prion SensorCindy Orser; Fiscal Year: 2002..PROPOSED COMMERCIAL APPLICATION: Beef and beef-by-products are omnipresent in foods, drugs, vaccines, and cosmetics, and the subclinical presence of an undiagnosed epidemic of transmissible spongiform encephalopathy (TSE) could ..
- BARRIER FUNCTION IN NORMAL IMMORTALIZED KERATINOCYTEALLEN COMER; Fiscal Year: 2001..Such tests are needed to prevent the inclusion of ingredients in consumer products, cosmetics or topically applied pharmaceuticals that would damage this critical function of skin...
- Reporter gene assays for skin irritation assessmentALLEN COMER; Fiscal Year: 2001..Such tests are needed to prevent the inclusion of irritating ingredients in consumer products, cosmetics, or topically applied pharmaceuticals...
- BIOSENSOR STUDIES OF ESTROGENIC COMPOUNDS WITH HER-A & BJUDITH ERB; Fiscal Year: 2002..Also diethyl phthalate, a compound widely used in colognes and cosmetics, selectively activates formation of stable complex between ERE and hER-alpha but not hER-beta...
- ARRAYS FOR BINAURAL ADAPTIVE DIRECTIONAL HEARING AIDScott Shaw; Fiscal Year: 2000..PROPOSED COMMERCIAL APPLICATION: The primary commercial application of the research is to improve both the cosmetics and the speech-in-noise performance of directional hearing devices, such as hearing aids or cochlear implants...
- Investigation of a Behavioral Substitute for SunbathingSherry Pagoto; Fiscal Year: 2007..Prevention interventions that target high-risk segments of the community in settings where risk behavior occurs have potential for a large and focused public health impact. [unreadable] [unreadable] [unreadable]..
- Guided Pocket Recolonization (GPR) in PeriodontitisMarc Quirynen; Fiscal Year: 2004..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
- Obesity and Negative Affect-Induced EatingSherry Pagoto; Fiscal Year: 2007..The University of Illinois at Chicago provides an ideal setting for training behavioral scientists and the mentoring team will provide a sound training experience for the PI from which an academic career can be launched. ..
- NNK, Beta-Adrenergic AA Release and Lung CancerHILDEGARD SCHULLER; Fiscal Year: 2005..2. To determine which products of the AA cascade are formed in untreated cells and in response to NNK, which of these products stimulate DNA synthesis, and what downstream effectors are activated by these products. ..
- Immortized Human Langerhans CellsSeyoum Ayehunie; Fiscal Year: 2002..Finally, a skin model containing immunologically competent cells would be extremely valuable to a large number of companies in evaluating whether their products are likely to cause allergic contact dermatitis...
- In Vitro Tissue Model of PsoriasisSeyoum Ayehunie; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Human Corneal Model for Ocular Irritation AssayYulia Kaluzhny; Fiscal Year: 2008..We will develop a corneal full thickness tissue and in vitro test methods that will dramatically reduce or eliminate the need to use animals to assess ocular irritancy of chemicals and products. [unreadable] [unreadable] [unreadable]..
- Tools for Targeted Delivery of DNA into Mammalian CellsALEXEY ZDANOVSKY; Fiscal Year: 2004..coil into mammalian cells. Also, we expect to lay a foundation for construction of customized bacteriophage-based DNA delivery systems suitable for genetic therapy applications. ..
- PROTEASE INHIBITOR-INDUCED HYPERLIPIDEMIA IN AIDSVirgil Brown; Fiscal Year: 2004..These are specific agents that are effective in reducing triglyceride as well as improving insulin resistance. ..
- Approach for amplification of molecular signalsALEXEY ZDANOVSKY; Fiscal Year: 2005..Bacterial luciferase will be incorporated in the naturally existing cascades of enzymatic reactions to produce an inexpensive and simple assay for the detection of antigens of interest including those of biowarfare agents. ..
- Biological Analysis of Toxic DEP ChemicalsAndre Nel; Fiscal Year: 2006..We will determine if inhaled ambient PM induce apoptosis in induced sputum samples in humans. ..
- Tanning bed use among UI StudentsLeslie Dennis; Fiscal Year: 2003..abstract_text> ..
- Community Based Clinical Trials Education ProgramGeorgia Sadler; Fiscal Year: 2006..The clinical trials. infrastructure has had extensive revisions to allow for accurate endpoint assessment with future efforts. ..
- Proteomics of DEP-induced Oxidative StressAndre Nel; Fiscal Year: 2006..They will also use a display of protein carbonyls to identity oxidatively modified proteins in the BAL fluid. ..
- Pre-validation of Tissue Specific Micronucleus Assay for Genotoxicity TestingYulia Kaluzhny; Fiscal Year: 2006..are also used; however, beginning in 2009, legislation in Europe will prevent manufacturers from marketing cosmetics products that have been tested using animals...
- Probes and cell arrays for detection of bacterial toxinsALEXEY ZDANOVSKY; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- Infection, Persistence & Clearance of Oral HPV in WomenJimmy Efird; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Atherogenic Effects of Ambient PM In Susceptible AnimalsAndre Nel; Fiscal Year: 2007..These mice will be exposed to CAPs as discussed in Aims 1 and 2, and select endpoints used to demonstrate the effect on atherosclerotic inflammation and apoptosis. ..
- Validation of Organotypic Vaginal Tissue Based Assay for Endocrine DisruptorsSeyoum Ayehunie; Fiscal Year: 2007..The proposed human organotypic tissue based assay will provide a sensitive and specific assay method to screen a large number of endocrine disrupting chemicals at a reduced cost. [unreadable] [unreadable] [unreadable]..
- Preclin. model for prevention of NSCLC in former smokersHILDEGARD SCHULLER; Fiscal Year: 2006....
- Development of methods and models for nanoparticle toxicity screening: ApplicatioAndre Nel; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- LIPID METABOLISM IN HUMAN KERATINOCYTESKATHI MADISON; Fiscal Year: 2004..Ultimately, these studies will contribute to fundamental knowledge about the regulation of epidermal differentiation at the molecular level. ..