Genomes and Genes
Summary: Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.
Publications282 found, 100 shown here
- Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controlsV Beral
Cancer Epidemiology Unit, Oxford, UK
Lancet 371:303-14. 2008b>Oral contraceptives were introduced almost 50 years ago, and over 100 million women currently use them...
- GnRH-analogues and oral contraceptives for fertility preservation in women during chemotherapyZeev Blumenfeld
Reproductive Endocrinology and Infertility Section, Department of Obstetrics and Gynaecology, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa 31096, Israel
Hum Reprod Update 14:543-52. 2008..Meanwhile, non-invasive techniques have attempted to minimize the gonadotoxic effect of chemotherapy, by using gonadotrophin-releasing hormone-analogues (GnRH-a) or oral contraceptives (OC).
- Anastrazole and oral contraceptives: a novel treatment for endometriosisLisa L Amsterdam
Indiana University School of Medicine, Indianapolis, Indiana, USA
Fertil Steril 84:300-4. 2005..To establish the use of aromatase inhibitors as a therapeutic option for endometriosis...
- Pregnancy outcome after exposure to oral contraceptives during the periconceptional periodH K Ahn
The Korean Motherisk Program, Cheil Hospital and Women s Health care Center, Kwandong University College of Medicine, Seoul, Korea
Hum Exp Toxicol 27:307-13. 2008To evaluate whether periconceptional exposure to oral contraceptives (OCs) increased adverse pregnancy outcomes, 136 pregnant women taking OCs within the periconceptional period were identified at the Korean Motherisk Program...
- Oral contraceptives and the risk of breast cancerPolly A Marchbanks
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 346:2025-32. 2002..We conducted a population-based, case-control study to determine the risk of breast cancer among former and current users of oral contraceptives.
- Oral contraceptives suppress cell proliferation and enhance apoptosis of eutopic endometrial tissue from patients with endometriosisGabriela F Meresman
Instituto de Biología y Medicina Experimental IBYME, Buenos Aires, Argentina
Fertil Steril 77:1141-7. 2002To evaluate the effects of administering combination oral contraceptives (COCs) to patients with endometriosis on the regulation of cell growth in the eutopic endometrium.
- Influence of gender and oral contraceptives on CYP2D6 and CYP2C19 activity in healthy volunteersS Hagg
Division of Clinical Pharmacology, Norrland University Hospital, Umea, Sweden
Br J Clin Pharmacol 51:169-73. 2001The study was carried out in order to assess the effects of gender and the use of oral contraceptives (OCs) on CYP2D6 and CYP2C19 activities in healthy volunteers.
- Relation of contraceptive and reproductive history to ovarian cancer risk in carriers and noncarriers of BRCA1 gene mutationsV McGuire
Department of Health Research and Policy and Medicine, Stanford University School of Medicine, Stanford, CA, USA
Am J Epidemiol 160:613-8. 2004..In both carriers and noncarriers, reduced risk was associated with ever use of oral contraceptives (odds ratio = 0.54 (95% confidence interval (CI): 0.26, 1.13) for carriers and 0.55 (95% CI: 0.41, 0...
- Selective exposure reporting and Medline indexing limited the search sensitivity for observational studies of the adverse effects of oral contraceptivesSusan Wieland
Department of Community Health, Center for Gerontology and Health Care Research, Brown University, Providence, RI 02912, USA
J Clin Epidemiol 58:560-7. 2005To explore development of possible approaches leading to a sensitive and precise Medline search to identify observational studies of the association between oral contraceptives and breast cancer, an adverse event.
- Oral contraceptives and androgenicity: influences on visuospatial task performance in younger individualsWhitney Wharton
Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA
Exp Clin Psychopharmacol 16:156-64. 2008The current study investigated whether the androgenic activity of oral contraceptives (OC) mediates performance on sexually dimorphic cognitive tasks in 155 younger individuals...
- The Coraliance study: non-compliant behavior. Results after a 6-month follow-up of patients on oral contraceptivesE Aubeny
Eur J Contracept Reprod Health Care 9:267-77. 2004..In those women who changed from a continuous cycle to an interrupted type of cycle, or vice versa, the study also aimed to evaluate the impact of this change on the pattern of omission of pills...
- The risk of oral contraceptives in the etiology of inflammatory bowel disease: a meta-analysisJulie A Cornish
Department of Biosurgery and Surgical Technology, St Mary s Hospital, Imperial College, London, United Kingdom
Am J Gastroenterol 103:2394-400. 2008..The aim of this study was to provide a quantification of the risk of oral contraceptive pill (OCP) use in the etiology of inflammatory bowel disease...
- Estrogens, oral contraceptives and hormonal replacement therapy increase the incidence of cutaneous melanoma: a population-based case-control studyE R Koomen
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, The Netherlands
Ann Oncol 20:358-64. 2009..Multiple studies showed conflicting results on the association between oral contraceptive (OC) use and the development of cutaneous melanoma (CM). We investigated the association between estrogen use and CM incidence...
- Oral contraceptives and increased headache prevalence: the Head-HUNT StudyK Aegidius
Department of Neuroscience, Norwegian National Headache Centre, St Olav s University Hospital, Trondheim, Norway
Neurology 66:349-53. 2006To examine the prevalence of headache and migraine among women using oral contraceptives (OCs) in a large, cross-sectional population-based study.
- Risk of stroke in women exposed to low-dose oral contraceptives: a critical evaluation of the evidenceWee Shian Chan
Departments of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Arch Intern Med 164:741-7. 2004....
- Treating acne with oral contraceptives: use of lower dosesJohannes Huber
Division of Gynecology and Infertility Treatment, Department of Obstetrics and Gynecology, Medical University Vienna, A 1090 Vienna, Austria
Contraception 73:23-9. 2006b>Oral contraceptives (OCs) have been shown to effectively treat acne...
- To what extent do oral contraceptives influence mood and affect?Kirsten A Oinonen
Department of Psychology, Lakehead University, Thunder Bay, Ont, Canada P7B 5E1
J Affect Disord 70:229-40. 2002Studies examining the effects of oral contraceptives (OCs) on mood, affect, and affect variability are reviewed.
- Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort studyJennifer Lin
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Am J Epidemiol 165:794-801. 2007..09). No significant association was observed between reproductive factors and colorectal cancer risk. These findings provide some support for a potential role of OCs in reducing risk of colorectal cancer...
- Effect of four different oral contraceptives on various sex hormones and serum-binding globulinsI Wiegratz
Department of Obstetrics and Gynecology, J W Geothe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
Contraception 67:25-32. 2003In a double-blind, controlled, randomized, four-arm, bicentric clinical study, the effect of four oral contraceptives (OCs) on various hormone parameters and serum-binding globulins was investigated...
- Oral contraceptives and breast cancer risk in Taiwan, a country of low incidence of breast cancer and low use of oral contraceptivesW C Chie
School of Public Health, College of Public Health, National Taiwan University, Taipei
Int J Cancer 77:219-23. 1998..Our results support the notion that OC use in early life for younger women and in early calendar years increase breast cancer risk...
- Primary dysmenorrhea in adolescent girls and treatment with oral contraceptivesA R Davis
Department of Obstetrics and Gynecology, Columbia University, 630 W 168th Street, New York, NY 10032, USA
J Pediatr Adolesc Gynecol 14:3-8. 2001..Combined oral contraceptives (COC) are an accepted treatment for dysmenorrhea in nonadolescent women...
- Oral contraceptives and individual variability of circulating levels of ethinyl estradiol and progestinsJoseph W Goldzieher
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 78212, USA
Contraception 78:4-9. 2008
- Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysisFrancesco Dentali
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Blood 107:2766-73. 2006Recent studies suggest that thrombophilic abnormalities and the use of oral contraceptives (OCs) are the leading causes of cerebral vein thrombosis (CVT)...
- Oral contraceptives, hormone replacement therapy and thrombosisF R Rosendaal
Department of Hematology, Leiden University Medical Center, The Netherlands
Thromb Haemost 86:112-23. 2001b>Oral contraceptives and hormone replacement therapy are used by hundreds of millions of women worldwide. Since the early 1960s it is known that female hormones increase the risk of venous thrombosis, myocardial infarction and stroke...
- The RATIO study: oral contraceptives and the risk of peripheral arterial disease in young womenM A A J van den Bosch
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
J Thromb Haemost 1:439-44. 2003With regard to oral contraceptives, much research has concentrated on venous thrombosis and on the coronary and cerebral forms of atherosclerotic disease, while peripheral arterial disease (PAD) has received little attention...
- Estrogen fluctuations, oral contraceptives and borderline personalityM Catherine DeSoto
Department of Psychology, University of Northern Iowa, Cedar Falls, IA 50614 0505, USA
Psychoneuroendocrinology 28:751-66. 2003..Inventory, Professional Manual, 1991) and a questionnaire that assessed time in menstrual cycle and use of oral contraceptives, that is synthetic estrogens...
- Influence of gender and oral contraceptives intake on innate and inflammatory response. Role of neuroendocrine factorsE Giraldo
Department of Physiology, Faculty of Sciences, University of Extremadura, 06071 Badajoz, Spain
Mol Cell Biochem 313:147-53. 2008..was to determine differences between young men (M), and women in the follicular phase (W) and women taking oral contraceptives containing ethinylestradiol (CW) in the phagocytic process of neutrophils (chemotaxis, phagocytosis and ..
- Have oral contraceptives reduced the prevalence of acne? a population-based study of acne vulgaris, tobacco smoking and oral contraceptivesGregor B E Jemec
Division of Dermatology, Department of Medicine, Roskilde University Hospital, Roskilde, Denmark
Dermatology 204:179-84. 2002..to describe the prevalence rate of acne among Danish adolescents and to study the possible influence of oral contraceptives (OC) and tobacco smoking on disease prevalence and severity...
- Oral contraceptive use and risk of breast cancer among women with a family history of breast cancer: a prospective cohort studyStephanie A N Silvera
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY 10461, USA
Cancer Causes Control 16:1059-63. 2005..Among women with any family history of breast cancer, ever use of oral contraceptives was associated with a 12% reduction in risk of breast cancer (95% confidence interval [CI]=0.73-1...
- Adolescents' cortisol responses to awakening and social stress; effects of gender, menstrual phase and oral contraceptives. The TRAILS studyEsther M C Bouma
Interdisciplinary Center for Psychiatric Epidemiology, University Medical Center Groningen CC 72, University of Groningen, Groningen, The Netherlands
Psychoneuroendocrinology 34:884-93. 2009..Effects of type of OC could not be studied because of low numbers of OC that were only progestin based...
- Serum folate and Vitamin B12 levels in women using modern oral contraceptives (OC) containing 20 microg ethinyl estradiolMarc W Sütterlin
Department of Obstetrics and Gynecology, University of Wurzburg, Josef Schneider Str 4, D 97080 Wurzburg, Germany
Eur J Obstet Gynecol Reprod Biol 107:57-61. 2003The effects of modern oral contraceptives (OC) on serum concentrations of folate and cobalamin are controversial.
- Oral contraceptives and colorectal cancer risk: a systematic review and meta-analysisCristina Bosetti
Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, 20156, Milan, Italy
Hum Reprod Update 15:489-98. 2009..Various studies have reported an inverse relation between oral contraceptive (OC) use and the risk of colorectal cancer, but the issue is still open...
- Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptivesI B Runnebaum
Department of Obstetrics and Gynecology, University of Ulm, Ulm, Germany
Pharmacogenetics 11:635-8. 2001b>Oral contraceptives have been shown to be protective against hereditary ovarian cancer...
- Parity and decreased use of oral contraceptives as predictors of asthma in young womenM A Jenkins
Department of Public Health, The University of Melbourne, Carlton, VIC 3053, Australia
Clin Exp Allergy 36:609-13. 2006..Asthma is more prevalent among males in childhood, but females report higher rates in adulthood. The reasons are unknown; although it has been hypothesized that hormonal factors may explain this sex-dependent risk of adult-onset asthma...
- Oral contraceptives as risk factors for cervical adenocarcinomas and squamous cell carcinomasJ V Lacey
National Cancer Institute, Bethesda, Maryland 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 8:1079-85. 1999To assess the hypothesis that oral contraceptives (OCs) increase the risk of cervical adenocarcinomas, we conducted a six-center case-control study of 124 patients with adenocarcinomas, 139 with squamous cell carcinomas, and 307 ..
- Association between sex hormone-binding globulin levels and activated protein C resistance in explaining the risk of thrombosis in users of oral contraceptives containing different progestogensHuib A A M van Vliet
Department of Gynaecology and Reproductive Medicine, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Hum Reprod 20:563-8. 2005Epidemiological studies have shown that both the estrogen dose and progestogen type of oral contraceptives contribute to the increased risk of thrombosis in oral contraceptive users...
- Use of oral contraceptives and breast cancer risk: The Norwegian-Swedish Women's Lifestyle and Health Cohort StudyMerethe Kumle
Institute of Community Medicine, University of Tromsoe, 9037 Tromsoe, Norway
Cancer Epidemiol Biomarkers Prev 11:1375-81. 2002Current use of oral contraceptives (OCs) has been reported to increase breast cancer risk slightly...
- Comparison of metabolic and inflammatory outcomes in women who used oral contraceptives and the levonorgestrel-releasing intrauterine device in a general populationLaure Morin-Papunen
Department of Obstetrics and Gynecology, University Hospital of Oulu, Oulu, Finland
Am J Obstet Gynecol 199:529.e1-529.e10. 2008We compared the metabolic and cardiovascular parameters of a reference group of women with those of women who used 2 contraceptive regimes that are used worldwide: the levonorgestrel-releasing intrauterine device and oral contraceptives.
- Antiepileptic drugs: coprescription of proconvulsant drugs and oral contraceptives: a national study of antiepileptic drug prescribing practiceS D Shorvon
Epilepsy Research Group, Institute of Neurology, Queen Square, London WC1N 3BG, UK
J Neurol Neurosurg Psychiatry 72:114-5. 2002To determine the frequency of coprescription of antiepileptic drugs (AEDs) and drugs with proconvulsant potential and of coprescription of AEDs and low dose oral contraceptives.
- Effects of oral contraceptives on peak exercise capacityGretchen A Casazza
Exercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, California 94720, USA
J Appl Physiol 93:1698-702. 2002..53 +/- 0.21 to 2.25 +/- 0.18 l/min). In conclusion, 1) endogenous ovarian steroids have little effect on VO(2 peak), but 2) the exogenous ovarian steroids in OC decrease peak exercise capacity in moderately physically active young women...
- Oral contraceptives and cervical cancer--further findings from the Oxford Family Planning Association contraceptive studyK T Zondervan
Department of Public Health and Primary Care, University of Oxford, Radcliffe Infirmary, UK
Br J Cancer 73:1291-7. 1996..results from the Oxford Family Planning Association contraceptive study regarding the association between oral contraceptives (OCs) and cervical neoplasia, after a 10 year follow-up of a cohort of 17,000 women...
- Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort studyM P Vessey
University Department of Public Health and Primary Care, Radcliffe Infirmary, Oxford, UK
Br J Cancer 71:1340-2. 1995Many case-control studies have shown that oral contraceptives protect against endometrial cancer and epithelial ovarian cancer, but little information is available from cohort studies...
- Metformin, naltrexone, or the combination of prednisolone and antiandrogenic oral contraceptives as first-line therapy in hyperinsulinemic women with polycystic ovary syndromeDijana Hadžiomerović-Pekić
Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Innsbruck, Innsbruck, Austria
Fertil Steril 94:2385-8. 2010....
- Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception studyPhilip C Hannaford
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen AB25 2AY
BMJ 335:651. 2007..To examine the absolute risks or benefits on cancer associated with oral contraception, using incident data...
- Oral contraceptives and risk of familial breast cancerKetil Heimdal
Unit of Medical Genetics, Norwegian Radium Hospital, University of Oslo
Cancer Detect Prev 26:23-7. 2002..For BRCA1 mutation carriers, the point estimate is a doubling of risk, but CI is wide and no conclusion may be drawn from this study alone...
- Oral contraceptive use, hormone replacement therapy, reproductive history and risk of colorectal cancer in womenGeoffrey C Kabat
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY 10461, USA
Int J Cancer 122:643-6. 2008..Ever use of oral contraceptives at baseline was associated with a modest reduction in the risk of colorectal cancer (hazard ratio 0...
- Cycle characteristics after discontinuation of oral contraceptivesC Gnoth
Department of Reproductive Medicine and Gynecological Endocrinology, Frauenklinik Duesseldorf Benrath, Duesseldorf, Germany
Gynecol Endocrinol 16:307-17. 2002Nearly 60% of the women between 20 and 40 years of age who do not want to conceive choose oral contraceptives (OCs) for contraception in Germany...
- Effects of two low-dose oral contraceptives containing ethinylestradiol and either desogestrel or levonorgestrel on serum lipids and lipoproteins with particular regard to LDL sizeT Foulon
Départment de Biologie Intégrée, CHU, BP217, Grenoble Cedex 09, France
Contraception 64:11-6. 2001This study was designed to determine the effects of two low-dose oral contraceptives, most frequently given in our area, monophasic desogestrel/ethinylestradiol (DG/EE) and triphasic levonorgestrel/ethinylestradiol (LNG/EE), on ..
- Use of oral contraceptives and mortality during 14 years' follow-up of Norwegian womenSidsel Graff-Iversen
Norwegian Institute of Public Health, Oslo, Norway
Scand J Public Health 34:11-6. 2006The aim was to evaluate total and cardiovascular disease (CVD) mortality in relation to use of oral contraceptives (OC) in a cohort of women with a relatively high prevalence of smoking and high serum lipid levels.
- Diurnal rhythm and effects of oral contraceptives on serum dehydroepiandrosterone sulfate (DHEAS) are related to alterations in serum albumin rather than to changes in adrenocortical steroid secretionK Carlstrom
Department of Obstetrics and Gynecology, Clinical Research Center, Karolinska Institutet, Huddinge University Hospital, Sweden
Scand J Clin Lab Invest 62:361-8. 2002..Although of adrenocortical origin, serum DHEAS levels are decreased by oral contraceptives (OCs). DHEAS is strongly bound to serum albumin and has a very low metabolic clearance rate...
- Oral contraceptives are not an independent risk factor for cervical intraepithelial neoplasia or high-risk human papillomavirus infectionsKari Syrjanen
Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland
Anticancer Res 26:4729-40. 2006..The aim of the present was study to analyse the risk estimates for OC users in order to develop several intermediate end-point markers in cervical carcinogenesis...
- Oral contraceptives, other methods of contraception, and risk reduction for ovarian cancerR B Ness
Graduate School of Public Health and Pittsburgh Cancer Institute, University of Pittsburgh, USA
Epidemiology 12:307-12. 2001b>Oral contraceptives reduce the risk of ovarian cancer, but the impact of other methods of contraception has not been fully explored. This population-based, case-control study involved women 20-69 years of age who had ever had intercourse...
- Improvement in quality-of-life questionnaire measures in obese adolescent females with polycystic ovary syndrome treated with lifestyle changes and oral contraceptives, with or without metforminMiranda Harris-Glocker
Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 601 Elmwood Avenue, Box 668, Rochester, NY 14642, USA
Fertil Steril 93:1016-9. 2010We studied the effect of metformin or placebo in a lifestyle modification program combined with oral contraceptives (OC) on quality-of-life parameters measured by the polycystic ovary syndrome (PCOS) questionnaire in obese adolescent ..
- Hypertension, genotype and oral contraceptivesPaolo Mulatero
Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, University of Torino, S San Vito 34 10133 Torino, Italy
Pharmacogenomics 3:57-63. 2002..In this article, the epidemiology and the pathogenesis of OCIH are reviewed with particular emphasis on the genetic influence in light of the most recent studies in this field...
- Oral contraceptives can cause falsely low vitamin B(12) levelsJ Gardyn
Hematology Unit, Golda Hasharon Campus, Rabin Medical Center, Petah Tikva, Israel
Acta Haematol 104:22-4. 2000..We evaluated 10 consecutive healthy women on oral contraceptives (OC) who had falsely low vitamin B(12) levels, as reflected by normal urine methylmalonic acid and plasma ..
- No sex-related differences but significant inhibition by oral contraceptives of CYP2C19 activity as measured by the probe drugs mephenytoin and omeprazole in healthy Swedish white subjectsK Laine
Department of Medical Laboratory Sciences and Technology, Karolinska Institutet, Huddinge University Hospital, Sweden
Clin Pharmacol Ther 68:151-9. 2000Although it is known that the use of oral contraceptives inhibits oxidative drug metabolism, there is little information regarding their effect on CYP2C19 activity...
- The effect of oral contraceptives on aromatase expression in the eutopic endometrium of patients with endometriosisHugo Maia
Centro de Pesquisa e Assistência em Reprodução Humana CEPARH, Salvador, Bahia, Brazil
Gynecol Endocrinol 24:123-8. 2008To determine the effect of oral contraceptives containing gestodene on aromatase expression in the endometrium of patients diagnosed with endometriosis.
- Effect of oral contraceptives on endothelial function in the peripheral microcirculation of healthy womenAgostino Virdis
Department of Internal Medicine, University of Pisa, Italy
J Hypertens 21:2275-80. 2003..We assessed whether third-generation oral contraceptive (OC) treatment (30 microg ethinylestradiol + 75 microg gestodene daily) could affect the endothelial function of healthy women...
- Benefits and risks of third-generation oral contraceptivesE S LeBlanc
Department of Internal Medicine, Portland Veterans Affairs Medical Center, Portland, OR, USA
J Gen Intern Med 14:625-32. 1999OBJECTIVE: To evaluate the risks and benefits of third-generation oral contraceptives. DATA SOURCES: A MEDLINE search was done for English language articles published from 1985 through 1998 relating to the side-effect profile of third-..
- Over-the-counter use of oral contraceptives in KuwaitM A Shah
Health Information Administration, Kuwait University, Kuwait
Int J Gynaecol Obstet 73:243-51. 2001..However, there is a need for better packaging and instructions that would enable high-risk women to identify themselves and to use OCPs under physician supervision...
- The effects of oral contraceptives including low-dose estrogen and drospirenone on the concentration of leptin and ghrelin in polycystic ovary syndromeNevin Sagsoz
Department of Obstetrics and Gynecology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey
Fertil Steril 92:660-6. 2009To evaluate short-term leptin and ghrelin concentrations in women with polycystic ovary syndrome (PCOS) who use low-dose oral contraceptives containing drospirenone.
- Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologiesHugo Maia
Centro de Pesquisas e Assistencia em Reproducao Humana CEPARH, 40210 341 Salvador, Bahia, Brazil
Contraception 78:479-85. 2008..The study was conducted to evaluate vascular endothelial growth factor (VEGF), Cox-2 and aromatase expression in the endometrium of uteri with myomas and other associated pathologies...
- Pro-inflammatory effects of oestrogens during use of oral contraceptives and hormone replacement treatmentC Kluft
Gaubius Laboratory, TNO PG, Vascular and Connective Tissue Research, Zernikedreef 9, P O Box 2215, 2333 CK Leiden, The Netherlands
Vascul Pharmacol 39:149-54. 2002The effects of two third-generation monophasic combined oral contraceptives (COC) and a postmenopausal hormone replacement therapy (HRT) consisting of 2 mg 17 beta-oestradiol on the plasma level of the acute-phase indicator C-reactive ..
- Risk of breast cancer associated with short-term use of oral contraceptivesSuzanne G Folger
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Cancer Causes Control 18:189-98. 2007..To estimate breast cancer risk associated with short-term (<6 months) oral contraceptive use, and explore variation in estimates by use characteristics and medical, menstrual, and reproductive history...
- Oral contraceptives and family history of breast cancerMary E Gaffield
Department of Reproductive Health and Research, World Health Organization, 1211 Geneva 27, Switzerland
Contraception 80:372-80. 2009..Questions remain regarding whether oral contraceptive (OC) use among women with a family history of breast cancer increases disease risk...
- Does use of estrogens decrease the Breslow thickness of melanoma of the skin? Oral contraceptives and hormonal replacement therapyElsje R Koomen
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands
Melanoma Res 19:327-32. 2009..This association was shown for both oral contraceptives (OC) and hormonal replacement therapy (HRT)...
- Non-contraceptive benefits of oral contraceptivesJohannes C Huber
University of Vienna School of Medicine, Department of Gynaecologic Endocrinology and Reproductive Medicine, Vienna, Austria
Expert Opin Pharmacother 9:2317-25. 2008There is increasing awareness of the opportunity that many contraceptive interventions may provide for additional health benefits. However, treatment of medical problems with oral contraceptives (OCs) is often an 'off-label' practice.
- Use of oral contraceptives in pregnancy and major structural birth defects in offspringDOROTHY KIM WALLER
The University of Texas, Houston Health Science Center, School of Public Health, Houston, TX 77030, USA
Epidemiology 21:232-9. 2010b>Oral contraceptives (OCs) are the most commonly used reversible contraceptive method among US women...
- Oral contraceptives and thrombotic disease: risk of venous thromboembolismF M Helmerhorst
Department of Obstetrics, Gynecology and Reproductive Medicine, Leiden University, The Netherlands
Thromb Haemost 78:327-33. 1997..The clinical consequence is therefore that second-generation OCs are the first choice in prescription to first-time users...
- Oral contraceptives improve endothelial function in amenorrheic athletesAnette Rickenlund
Research Laboratory for Reproductive Health, Department of Obstetrics and Gynecology, C4 U1, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
J Clin Endocrinol Metab 90:3162-7. 2005..The aim of this study was to evaluate the effects of oral contraceptives (OCs) on endothelial function measured as flow-mediated dilatation (FMD) of the brachial artery, the lipid ..
- Effects of oral contraceptives on sympathetic nerve activity during orthostatic stress in young, healthy womenJason R Carter
Dept of Exercise Science, Michigan Technological Univ, 1400 Townsend Drive, Houghton, MI 49931, USA
Am J Physiol Regul Integr Comp Physiol 298:R9-R14. 2010..The purpose of the present study was to determine whether oral contraceptives (OC) influence sympathetic neural activation during an orthostatic challenge...
- Early onset vulvar Lichen Sclerosus in premenopausal women and oral contraceptivesAndreas R Günthert
University of Goettingen, Department Obstetrics and Gynaecology, Robert Koch Str 40, 37075 Goettingen, Germany
Eur J Obstet Gynecol Reprod Biol 137:56-60. 2008..During the last decade an increase of LS in young women has been suspected. Aim of this study was to evaluate data of premenopausal women with early onset LS to find potential risk factors focussing on the use of oral contraceptives.
- Intrinsic coagulation activation and the risk of arterial thrombosis in young women: results from the Risk of Arterial Thrombosis in relation to Oral contraceptives (RATIO) case-control studyB Siegerink
Department of Clinical Epidemiology, LUMC, Leiden, The Netherlands
Circulation 122:1854-61. 2010..This study aims to determine the risks of arterial thrombosis conferred by increased activation of intrinsic coagulation proteins in young women and the effect of oral contraceptive use on this association...
- Oral contraceptives use and the risk of myocardial infarction: a meta-analysisYousef S Khader
Department of Biostatistics, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Contraception 68:11-7. 2003..48 [95% confidence interval (CI): 1.91-3.22] compared to never-users. The risk of MI for past OC users is not significantly different from that for never-users, overall OR = 1.15 (95% CI: 0.98-1.35; p = 0.096)...
- Effect of the menstrual cycle and oral contraceptives on cyclooxygenase-2 expression in the endometriumHugo Maia
CEPARH, Salvador, Bahia, Brazil
Gynecol Endocrinol 21:57-61. 2005To compare the expression of cyclooxygenase-2 (COX-2) and proliferation markers (Ki-67) in the endometrium of patients with ovulatory cycles with those in the endometrium of patients using oral contraceptives.
- Influence of smoking and oral contraceptives on bone mineral density and bone remodeling in young women: a 2-year studyC Elgán
Department of Nursing, Lund University, P O Box 157, S 221 00, Lund, Sweden
Contraception 67:439-47. 2003The objective of the study was to explore the influence of menstrual irregularities, oral contraceptives and smoking on bone mineral density (BMD) development and bone turnover with time...
- Association between efficacy and body weight or body mass index for two low-dose oral contraceptivesRonald T Burkman
Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, MA 01199, USA
Contraception 79:424-7. 2009..This analysis investigated the association of oral contraceptive efficacy with body weight and body mass index (BMI) for hypothesis-generating purposes...
- Risk of venous thromboembolism from oral contraceptives containing gestodene and desogestrel versus levonorgestrel: a meta-analysis and formal sensitivity analysisS Hennessy
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Contraception 64:125-33. 2001Controversy exists regarding whether oral contraceptives (OCs) containing desogestrel and gestodene are associated with an increased risk of venous thromboembolism (VTE) versus OCs containing levonorgestrel...
- Cyclooxygenase-2 expression in the endometrium and its relationship to bleeding in users of continuous oral contraceptivesHugo Maia
Centro de Pesquisa e Assistência em Reprodução Humana CEPARH, Salvador, Bahia, Brazil
Gynecol Endocrinol 22:96-100. 2006The objective of the present study was to investigate whether or not the presence of irregular bleeding during use of oral contraceptives (OC) is associated with increased cyclooxygenase-2 (COX-2) expression.
- Oral contraceptives and DDAVP nasal spray: patterns of use in managing vWD-associated menorrhagia: a single-institution studyLawrence S Amesse
Section of Pediatric Adolescent Gynecology, Division of Reproductive Endocrinology and Infertility, Wright State University School of Medicine, Dayton, Ohio 45409, USA
J Pediatr Hematol Oncol 27:357-63. 2005..Subjects with vWD type 1 (n = 36) administered either oral contraceptives (OC) or intranasal desmopressin acetate (DDAVP) and followed from 6 months to 4 years were selected for ..
- Systematic review of case-control studies: oral contraceptives show no effect on melanoma riskA Pfahlberg
Department of Medical Statistics, University of Gottingen, Germany
Public Health Rev 25:309-15. 1997....
- Effect of second and third generation oral contraceptives on C-reactive protein, lipids and apolipoproteins in young, non-obese, non-smoking apparently healthy womenMagdalena Krintus
Department of Laboratory Medicine, Collegium Medicum, Nicolaus Copernicus University, ul M Sklodowskiej Curie 9, 85 094 Bydgoszcz, Poland
Clin Biochem 43:626-8. 2010Third generation oral contraceptives (OC) may increase the risk of cardiovascular events in healthy young women.
- Oral contraceptives, hormone replacement therapy and the risk of colorectal cancerE Fernandez
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
Br J Cancer 73:1431-5. 1996The relationship between oral contraceptives (OCs), menopausal hormone replacement therapy (HRT) and the risk of colorectal cancer was investigated in a case-control study conducted in northern Italy between 1985 and 1992 on 709 women ..
- Effects of oral contraceptives on total serum proteins, albumin, globulins and cholesterol levels in Ibadan, NigeriaK A Obisesan
Department of Obstetrics and Gynaecology, College of Medicine University of Ibadan, Nigeria
West Afr J Med 21:197-9. 2002..protein, albumin, globulin, albumin/globulin ratio and cholesterol levels were determined in 25 subjects on oral contraceptives and 25 controls...
- Effects of oral contraceptives on diurnal profiles of insulin, insulin-like growth factor binding protein-1, growth hormone and cortisol in endurance athletes with menstrual disturbanceA Rickenlund
Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska Institutet, SE 171 76 Stockholm, Sweden
Hum Reprod 25:85-93. 2010....
- Effect of low-dose oral contraceptives on metabolic risk factors in African-American womenBarbara A Frempong
Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
J Clin Endocrinol Metab 93:2097-103. 2008..The effect of oral contraceptive pill (OCP) use on cardiovascular risk in African-American women is unknown...
- Acute renal vein thrombosis, oral contraceptives, and protein S deficiency: a successful catheter-directed thrombolysisHyung Kee Kim
Division of Transplantation and Vascular Surgery, Department of Surgery, Kyungpook National University School of Medicine, Daegu, South Korea
Ann Vasc Surg 23:687.e1-4. 2009..a case of acute RVT with multiple pulmonary emboli that occurred in a 40-year-old woman who was taking oral contraceptives and was subsequently found to have protein S deficiency...
- Decreased mechanical pain threshold in the vestibular mucosa of women using oral contraceptives: a contributing factor in vulvar vestibulitis?Nina Bohm-Starke
Division of Obstetrics and Gynaecology, Karolinska Institutet Danderyd Hospital, Stockholm, Sweden
J Reprod Med 49:888-92. 2004To analyze possible differences in somatosensory perception in the vestibular mucosa in healthy women associated with the use of oral contraceptives.
- Hormonal content and potency of oral contraceptives and breast cancer risk among young womenM D Althuis
Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 7084, EPS MSC 7234, Rockville, MD 20852 USA
Br J Cancer 88:50-7. 2003..Hormonal content and potency of combination oral contraceptives used for the longest duration within 5 years of interview for breast cancer cases aged 20-44 years (N=1640) ..
- Oral contraceptives and the risk of ductal breast carcinoma in situElizabeth B Claus
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Breast Cancer Res Treat 81:129-36. 2003..No study has examined the relationship between oral contraceptive use and the risk of non-invasive breast carcinoma, that is, breast carcinoma in situ...
- Association between the current use of low-dose oral contraceptives and cardiovascular arterial disease: a meta-analysisJean Patrice Baillargeon
Department of Internal Medicine, Universite de Sherbrooke, Endocrine Division, 3001 12th North Avenue, Sherbrooke, Quebec J1H 5N4, Canada
J Clin Endocrinol Metab 90:3863-70. 2005The long-term cardiovascular safety of widely used oral contraceptives (OCs) is still debated, and no meta-analysis assesses the modern use of OCs and the associated cardiovascular risks.
- Assessment of DNA damage in women using oral contraceptivesAydan Biri
Department of Obstetric and Gynecology, School of Medicine, Gazi University, Ankara, Turkey
Mutat Res 521:113-9. 2002....
- Effect of injectable and oral contraceptives on serum lipidsAbbey B Berenson
Department of Obstetrics and Gynecology, the Center for Interdisciplinary Research in Women s Health, The University of Texas Medical Branch, Galveston, Texas 77555 0587, USA
Obstet Gynecol 114:786-94. 2009To estimate the effects of using depot medroxyprogesterone acetate (DMPA) or oral contraceptives (OCs) containing 20 micrograms ethinyl estradiol and 0.15 mg desogestrel on serum lipid levels.
- Facilitated acquisition of the classically conditioned eyeblink response in women taking oral contraceptivesKevin D Beck
Neurobehavioral Research Laboratory, VA New Jersey Health Care System, East Orange, New Jersey 07018, USA
Behav Pharmacol 19:821-8. 2008..Therefore, in this preliminary study we assessed learning in women who take oral contraceptives and those who do not during the three phases of the menstrual cycle: early, middle, and later cycle...
- Venous thromboembolism in young female while on oral contraceptives: high frequency of inherited thrombophilia and analysis of thrombotic events in 400 czech womenPetr Dulicek
Second Department of Internal Medicine Division of Hematology, University Hospital and Medical Faculty of Charles University, Hradec Kralove, Czech Republic
Clin Appl Thromb Hemost 15:567-73. 2009..Oral contraceptive use is a common risk factor for venous thromboembolism in women of reproductive age. The presence of inherited thrombophilia further increases this risk...
- Effects of putative male pheromones on female ratings of male attractiveness: influence of oral contraceptives and the menstrual cycleFrances Thorne
Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne, UK
Neuro Endocrinol Lett 23:291-7. 2002..The results of this study suggest that exposure to natural male axillary pheromones can significantly enhance female perceptions of various aspects of male attractiveness...
- Risk of hyperkalemia in women taking ethinylestradiol/drospirenone and other oral contraceptivesJeanne Loughlin
Ingenix i3 Drug Safety, Waltham, MA 02451, USA
Contraception 78:377-83. 2008..We sought to determine whether EE/DRSP use might lead to adverse effects possibly attributable to hyperkalemia...
- [Use of oral contraceptives and increased risk of cervical cancer]C E Schmeink
Universitair Medisch Centrum St Radboud, afd Verloskunde en Gynaecologie, Postbus 9101, 6500 HB Nijmegen
Ned Tijdschr Geneeskd 152:1717-8. 2008A recently published meta-analysis and a large cohort study showed independently that use of oral contraceptives (OC) leads to an increased relative risk (RR) of cervical cancer. This RR increased with the duration of OC use and was 1...
- Risk of venous thromboembolism and the use of dienogest- and drospirenone-containing oral contraceptives: results from a German case-control studyJürgen Dinger
Director, ZEG Berlin Center for Epidemiology and Health Research, Invalidenstrasse 115, 10115 Berlin, Germany
J Fam Plann Reprod Health Care 36:123-9. 2010..e. containing < or =30 microg EE), particularly oral contraceptives containing levonorgestrel (LNG)...
- Oral contraceptives: a risk factor for uncontrolled blood pressure among hypertensive womenJaqueline Neves Lubianca
Programa de Pós Graduação em Ciências Médicas Clínica Médica, 2 degrees andar Faculde de Medicina da Universidade Federal do Rio Grande do Sul UFRGS, Rua Ramiro Barcelos 2400, CEP 90035 003, Porto Alegre, RS, Brazil
Contraception 67:19-24. 2003..was to assess the association between systolic and diastolic blood pressure (SBP and DBP) and the use of oral contraceptives (OC) in hypertensive women...
- Different oral contraceptives and voice quality--an observational studyOfer Amir
Department of Communication Disorders, Sackler Faculty of Medicine, Tel Aviv University, 52621 Israel
Contraception 71:348-52. 2005The classical literature on endocrine effect on voice considers oral contraceptives (OCs) as a risk factor for voice. However, recent studies revealed no adverse effect of new-generation OCs on voice...
- The Primate Corpus Luteum: Functional Regression and Cardiovascular ImpactsRandy L Bogan; Fiscal Year: 2012..cycle-induced changes in cardiovascular risk factors and how inhibiting ovarian activity via hormonal oral contraceptives affects these factors...
- Vitamin B6 Effects on One-Carbon MetabolismJesse F Gregory; Fiscal Year: 2013..segment of the population, women of reproductive age, has compromised B6 status associated with the use of oral contraceptives (OC)...
- A Novel Target for the Treatment of EndometriosisPaul D Crowe; Fiscal Year: 2011..therapy carries a significant risk of bone loss, is not obviously more effective than treatment with oral contraceptives, and also has a 50% or higher recurrence of symptoms within 5 years...
- Innate immunity predictors of HIV: the role of contraception, pregnancy and HSV-2Charles Morrison; Fiscal Year: 2013..HC), including the injectable progestin depot medroxyprogesterone acetate (DMPA) and combined oral contraceptives (COCs), and pregnancy have been associated with increased risk of HIV in some, but not all, large ..
- Risk Factors for Urinary Incontinence in WomenFrancine Grodstein; Fiscal Year: 2010..may increase risk of developing UI, we also propose novel and detailed analyses of the relation between oral contraceptives and UI in premenopausal women...
- Role of NRF-1 in Estrogen-Induced Breast Cancer PathogenesisDeodutta Roy; Fiscal Year: 2013DESCRIPTION (provided by applicant): Exposure to exogenous estrogen used in oral contraceptives (OCs) and hormone therapy (HT) is a major risk factor for breast cancer initiation and progression in women including veteran population...
- FACTOR VA INTERACTIONS REGULATING PROTHROMBIN ACTIVATIONPaul E Bock; Fiscal Year: 2010..defects in the coagulation factors, factor V, protein C, protein S, and prothrombin, and women taking oral contraceptives have a higher risk of clotting in veins...
- Smoking, Sex Hormones and PregnancySharon S Allen; Fiscal Year: 2013..between sex hormones and smoking-related symptomatology in pregnancy and, a more controlled clinical model, oral contraceptives. We will address this objective by assessing two specific study aims: (1) investigate the association ..
- Gonadotropins &Cox-2 in Ovarian Cancer PreventionXIANGXI MIKE XU; Fiscal Year: 2013..cancer risk factors, such as high cancer incidence in peri- postmenopausal ages and preventive activity of oral contraceptives. However, the mechanisms for these well-established ideas remain obscure, and experimental systems are ..
- Prevention of Menopause-Related Ovarian Epithelial CancerElizabeth R Smith; Fiscal Year: 2010..where uninterrupted ovulation frequency and non-parity increase the risk, and parity and the use of oral contraceptives clearly reduce the risk...
- Oral contraceptive use by formulation and breast cancer risk by subtypeDIANA SM BUIST; Fiscal Year: 2010DESCRIPTION (provided by applicant): Project Summary/Abstract Approximately 82% of US women have ever used oral contraceptives (OCs) during their reproductive lives and there is a modest increased risk of breast cancer associated with ..
- A Pooled Analysis to Identify New Ovarian Cancer Risk FactorsCeleste Leigh Pearce; Fiscal Year: 2010..While it is clear that exogenous hormones in the form of oral contraceptives (OCs) are associated with decreased risk of epithelial ovarian cancer (ovarian cancer), the situation with ..
- Oral Contraceptives in the Etiopathogenesis of Crohn's DiseaseHamed Khalili; Fiscal Year: 2013..In prior work, the candidate has demonstrated that use of oral contraceptives (OC) is associated with an increased risk of developing CD...
- Oral Contraceptive Use and Fractures Around the Menopausal TransitionDelia Scholes; Fiscal Year: 2012..Combined oral contraceptives (OCs), the leading method of contraception in the U.S...
- Modulation of Hormonal and Systemic Immunity by Hormonal Contraceptive UseThomas L Cherpes; Fiscal Year: 2013..generate a fresh approach to this research question that focuses on the immunomodulatory effects of DMPA, oral contraceptives (OC), and levonorgestrel-containng intrauterine devices (LNG-IUD) that may impair host responses against ..
- Long-term Follow-Up of Infertility Patients: A Pilot StudyFrancine Grodstein; Fiscal Year: 2010..Although health effects of hormonal treatments such as oral contraceptives and postmenopausal hormone therapy have been well- documented, surprisingly little is known regarding the ..
- Effects of Continuous versus Cyclic Oral Contraceptives on Mammary Tumor GrowthPATRICIA ANN MASSO-WELCH; Fiscal Year: 2013..The primary outcome of these studies is to define the effects of continuous dosing of OC on primary and metastatic mammary tumor growth in two distinct mouse mammary tumor models, relative to no OC or cyclic dosing of OC. ..
- Prolactin as a lacrimal gland immunomodulatorJoel Schechter; Fiscal Year: 2009..puerperium, and lactation, and in a setting of elevated systemic E2 mimicking that of a woman using oral contraceptives. Together, Aims 1 and 2 test the hypothesis that certain endocrinological states allow the system to ..
- Mechanisms of Prevention of Ovarian Cancer by Oral ContraceptivesMalcolm C Pike; Fiscal Year: 2013....
- Elucidating the mechanism of ERbeta in colon carcinogenesisCECILIA MARIE WILLIAMS; Fiscal Year: 2013..hormone replacement therapy in women unexpectedly resulted in reduced risk of colorectal cancer, use of oral contraceptives is associated with a lower incidence of this disease, and estradiol has been shown to reduce the formation ..
- Reproductive Hormones and their impact on HIV-1 acquisitionBharat Ramratnam; Fiscal Year: 2013..during different phases of the menstrual cycle, before/after starting hormonal contraception (high dose oral contraceptives vs. low dose oral contraceptives vs. DMPA) and before/after starting estrogenic creams...
- Fertility and Oral Contraceptive Use Study (FOCUS)Larissa R Brunner Huber; Fiscal Year: 2010b>Oral contraceptives (OCs) are the most popular reversible method of contraception in the US...
- Ovulation, inclusion cysts, and p53 mutations in a mouse model of ovarian cancerJoanna E Burdette; Fiscal Year: 2010..For example, pregnancy, breast-feeding, use of oral contraceptives, and early menopause all reduce the risk for developing ovarian cancers...
- Fat Mediated Modulation of Reproductive and Endocrine Function in Young AthletesMadhusmita Misra; Fiscal Year: 2013..Despite the prevalent practice of prescribing oral contraceptives in AA, there is a paucity of data regarding benefits of this intervention in teenagers...
- Hormonal Contraception and HIV Acquisition: An IPD Meta-analysisCharles Morrison; Fiscal Year: 2012..use including the injectable progestin, depot-medroxyprogesterone acetate (DMPA), and combined oral contraceptives (OCs)...
- A novel vaginal ring to prevent HIV and HSV-2 infection, as well as pregnancyTHOMAS MICHAEL ZYDOWSKY; Fiscal Year: 2013..prevents SHIV-RT and HSV-2 infection in vivo;and LNG is the most widely used progestin in approved oral contraceptives (in combination with ethinyl estradiol or alone in low dose progestin only contraceptives)...
- Levonorgestrel intrauterine system versus oral contraceptives for heavy mensesKristen A Matteson; Fiscal Year: 2013..In the United States, combined oral contraceptives and the levonorgestrel intrauterine system are the two most commonly prescribed non-surgical treatments for ..
- RCT of a Novel Oral Contraceptive Initiation MethodCarolyn Westhoff; Fiscal Year: 2004Description (provided by applicant): Pregnancy rates are high among acceptors of oral contraceptives despite the effectiveness of the method...
- GENETIC SUSCEPTIBILITY TO HORMONAL CARCINOGENESISROLF PERSSON; Fiscal Year: 2000..factors-like nulliparity, late age at first birth, early menarche, late menopause, long-term use of oral contraceptives or hormone replacement therapy-together with first-degree family history, explain only half of all breast ..
- MUTATIONS, HORMONE THERAPY, AND VENOUS THROMBOEMBOLISMBruce Psaty; Fiscal Year: 2001..In pre-menopausal women, the use of oral contraceptives is associated with a 4-fold increase in VTE risk, and the joint effects of oral contraceptive use and ..
- TRACE ELEMENT NUTRITION OF THE LENS--ZINCJ Bentley; Fiscal Year: 1990..diseases, including diabetes mellitus and diarrheal disease, and the use of some drugs such as ethanol, oral contraceptives and thiazide diuretics. Some such conditions are known to result in a predisposition to cataracts in humans...
- DIET, ACTIVITY & REPRODUCTION--RISKS FOR RECTAL CANCERMARTHA OR MARTY SLATTERY; Fiscal Year: 1999..associated with an increased risk of colon cancer; 4) nulliparity, late age at first birth and non-use of oral contraceptives are associated with an increased risk of colon cancer; 5) family history of colon cancer is associated with ..
- ORAL CONTRACEPTIVES AND THROMBOEMBOLIC DISEASEStephen Sidney; Fiscal Year: 2000..Finally, they point out that it would provide estimates of the prevalence of the Factor V Leiden mutation and its impact on thromboembolic disease in a racially heterogeneous California study population. ..
- Treatment of Endometriosis-Associated Pelvic PainDavid Guzick; Fiscal Year: 2007..As an alternative, the continuous use of oral contraceptives has been advocated as a practical, inexpensive strategy for long-term medical treatment of endometriosis-..
- ROLE OF STROMA IN MAMMARY GLAND CELL PROLIFERATIONSANDRA HASLAM; Fiscal Year: 2007..Since P are widely used in oral contraceptives and in postmenopausal hormone replacement therapy it is critically important that their mechanims of action ..
- A RCT of LNG-IUD vs. DMPA for young postpartum womenNancy Stanwood; Fiscal Year: 2005..DMPA) is a highly effective method of contraception, with better compliance and lower pregnancy rates than oral contraceptives. It is commonly recommended to young women for postpartum contraception...
- ECTOPY, HORMONAL CONTRACEPTION AND STD'S IN ADOLESCENTSLigia Peralta; Fiscal Year: 2004..Cervical ectopy and use of oral contraceptives (OC), both common in adolescence, are risk factors for chlamydia, the most common inflammatory STD...
- Inflammatory Markers in Circulation and Ovarian Cancer RiskAlan Arslan; Fiscal Year: 2009..Conversely, factors that suppress ovulation (pregnancy, lactation, and use of oral contraceptives) and possibly use of anti-inflammatory medications are associated with reduced risk...
- ASSESSING RECALL ACCURACY FOR PRESCRIPTION MEDICATIONSSuzanne West; Fiscal Year: 1991..Except for drugs such as estrogens and oral contraceptives, little attention has been focused on the validity of patient histories of prior drug exposures...
- ORAL CONTRACEPTIVES: EFFECT ON VITAMIN C METABOLISMK Lei; Fiscal Year: 1980..The in vitro reactions will be monitored by measuring the quantities of products formed or the remaining substrate...
- PAIN AND ANALGESIC RESPONSE--SEX AND HORMONE VARIATIONSSandra Comer; Fiscal Year: 2002..Further, each study will compare normally-cycling women to women maintained on oral contraceptives and to men...
- 60-HZ MAGNETIC FIELDS AND HORMONE LEVELS IN WOMENScott Davis; Fiscal Year: 2000..not been previously diagnosed with breast cancer, who reports regular menstrual periods, who is not taking oral contraceptives or hormone preparations, and who normally sleeps with an electric blanket during the winter months...
- ORAL CONTRACEPTIVES AND INFLAMMATORY BOWEL DISEASE RISKEdward Boyko; Fiscal Year: 1992The main goals of this study are (1) to determine whether current and past use of oral contraceptives alter a woman's risk of developing ulcerative colitis (2) to determine whether alteration in risk due to oral contraceptive use varies ..
- LONG ORAL CONTRACEPTIVE USE/VITAMIN B-6 PREGNANCY NEEDSAvanelle Kirksey; Fiscal Year: 1980..nutritional status of women who may be at risk of a deficiency of the vitamin following long-term use of oral contraceptives (OCA)...
- ROLE OF GONADAL STEROIDS IN LIVER CARCINOGENESISJAMES YAGER; Fiscal Year: 1980Recently, numerous reports have appeared describing the presence of liver-cell adenomas in women using oral contraceptives. Animal studies conducted at the time these agents were originally tested foretold of the possibility, but it was ..
- ETHINYL ESTRADIOL AND HEPATOCARCINOGENESISJAMES YAGER; Fiscal Year: 2003Prolonged use by women of oral contraceptives containing the synthetic ethinyl estradiol (EE) is associated with a modest increased risk of developing liver tumors...
- CHEMOPREVENTION OF BREAST AND OVARIAN CANCERPowel Brown; Fiscal Year: 2004..2) Chemoprevention of Ovarian Cancer: Marker Modulation using Fenretinide and Oral Contraceptives. This project will investigate whether oral contraceptives, the synthetic retinoid 4HPR or their ..
- PROSPECTIVE STUDY OF STRESS AND MOOD IN CHRONIC HEADACHEEdward Blanchard; Fiscal Year: 1999..and, when appropriate, indications of two key points in the menstrual cycle of premenopausal women not on oral contraceptives: time of ovulation and time of onset of menstruation...
- CatSper: Novel target for an oral contraceptiveJAYHONG CHONG; Fiscal Year: 2003Hydra Biosciences Inc. will develop a novel class of non-hormonal, oral contraceptives based on the discovery by our co-founder, David Clapham, M.D./ Ph.D., of a sperm specific ion channel, CatSper...
- HPV methylation: a biomarker of cervical lesion progressAnna Giuliano; Fiscal Year: 2003..2) whether methylation patterns of HPV are related to viral load; 3) the factors (such as smoking, oral contraceptives, and co-infections) associated with HPV methylation status; 4) whether HPV DNA methylation status is ..
- CASE-CONTROL STUDY OF ADENOCARCINOMA OF THE CERVIXRuth Peters; Fiscal Year: 1991The LONG-TERM OBJECTIVE of this proposal is to conduct a case-control study to investigate the role of oral contraceptives (OC's) in the etiology of adenocarcinoma of the uterine cervix...
- A NOVEL ORAL CONTRACEPTIVE INITIATION METHODPatricia Murphy; Fiscal Year: 2000..The main reason is non-use of effective contraceptives. Oral contraceptives are one of the most effective of methods, but even after they are prescribed, pregnancy rates remain high...
- ORAL CONTRACEPTION AND ATHEROSCLEROSISMichael Adams; Fiscal Year: 1993While oral contraceptives have been in widespread use for about 25 years, the effects of these compounds on risk of coronary heart disease (CHD) remain unclear...
- POSTMENOPAUSAL PROGESTINS & THE RISK OF CORONARY DISEASEBruce Psaty; Fiscal Year: 1992..Progestins are probably responsible for the increased risk of myocardial infarction (MI) in women on oral contraceptives. Does the addition of progestins pose a risk for fatal and non-fatal MI in post-menopausal women on ..
- BRCA1, ORAL CONTRACEPTIVES, AND HORMONAL RISK FACTORSLeslie Bernstein; Fiscal Year: 2003..abstract_text> ..
- ORAL CONTRACEPTIVES AND CANCERJames Schlesselman; Fiscal Year: 1991..Finally, estimates of cumulative cancer incidence will be computed to evaluate the overall public health importance of apparently causal relationships...
- NIGHT SHIFT WORKERS AND HORMONE LEVELS IN WOMENScott Davis; Fiscal Year: 2006..ages of 20 and 40, employed for at least 20 hours/week, resident of King or Snohomish County, do not take oral contraceptives or other hormone preparations, and have no personal history of breast cancer...
- Psychological Symptoms and Oral Contraceptive Continuation in Young MinoritiesKelli Stidham Hall; Fiscal Year: 2009..Although oral contraceptives (OCs) are the safest and most effective method of birth control, their use by sexually active adolescents ..
- Mechanisms underlying the anatomically specific actions of estradiol in brain.KEITH LANCE GONZALES; Fiscal Year: 2010..despite a full understanding of its actions, which has lead to behavioral and mood disorders in women using oral contraceptives. Furthermore, estradiol has recently been associated with a number of neurological disorders including ..
- Genetic Variants of Hormone Receptors in Ovarian CancerKathryn Terry; Fiscal Year: 2003..epidemiologic literature suggests a protective effect for the combination of estrogen and progesterone in oral contraceptives, which are consistently protective...
- HORMONAL CONTRACEPTIVES AND INVASIVE CERVICAL CANCERSamuel Shapiro; Fiscal Year: 2000..been posited that injectable progestogen-only contraceptives (IPCs) and/or combined estrogen-progestogen oral contraceptives (COCs) may act as cofactors, together with HPV, in the aetiology of cervical cancer...
- CASE-CONTROL STUDY OF BREAST CANCER IN YOUNG WOMENLeslie Bernstein; Fiscal Year: 1991Although there ius no strong evidence that oral contraceptives (OCs) have an effect on breast cancer risk when used during the middle reproductive years, women who use OCs for long periods of time in the post-menarcheal period may be at ..
- Effect of Estrogen on Radiation-induced CataractogenesisJOSEPH DYNLACHT; Fiscal Year: 2005..High estrogen levels are artificially induced in nonpregnant women using oral contraceptives, or in post-menopausal women on estrogen replacement therapy, and these groups may be at an increased risk ..
- HORMONAL REPLACEMENT THERAPY AND RISK OF COLON CANCERJean Paul Collet; Fiscal Year: 1999..Also obtained from the SPDP for this same time period will be prescription information on oral contraceptives and NSAIDs...