Genomes and Genes
female contraceptive agents
Summary: Chemical substances or agents with contraceptive activity in females. Use for female contraceptive agents in general or for which there is no specific heading.
Publications215 found, 100 shown here
- Bleeding problems and progestogen-only contraceptionCharlotte Porter
Victoria Clinic, Nottingham, UK
J Fam Plann Reprod Health Care 28:178-81. 2002
- Advances in hormonal contraceptionNupur Gupta
Tufts University School of Medicine, Boston, MA 02111, USA
Adolesc Med Clin 17:653-71; abstract xi. 2006..The article provides a short description of each of these contraceptive methods, information about compliance, side effects, and efficacy, and an update on that particular method...
- Hormonal contraception and risk of sexually transmitted disease acquisition: results from a prospective studyJ M Baeten
Department of Epidemiology, University of Washington, Seattle, WA 98104 2499, USA
Am J Obstet Gynecol 185:380-5. 2001..To examine the relationship between use of oral contraceptive pills or depot medroxyprogesterone acetate and sexually transmitted disease acquisition...
- Perivascular smooth muscle alpha-actin is reduced in the endometrium of women with progestin-only contraceptive breakthrough bleedingP A Rogers
Monash University Department of Obstetrics and Gynaecology, Monash Medical Centre, Victoria, Australia
Hum Reprod 15:78-84. 2000....
- Hormonal contraceptive use, herpes simplex virus infection, and risk of HIV-1 acquisition among Kenyan womenJared M Baeten
Seattle HIV Prevention Trials Unit, Department of Medicine, University of Washington, 9012 Boren Avenue, Seattle, WA 98104, USA
AIDS 21:1771-7. 2007..A recent study from Uganda and Zimbabwe found that women using hormonal contraception were at increased risk for HIV-1 if they were seronegative for herpes simplex virus type 2 (HSV-2), but not if they were HSV-2 seropositive...
- Pregnancy in effectiveness trials of HIV prevention agentsElizabeth G Raymond
Family Health International, Research Triangle Park, North Carolina, USA
Sex Transm Dis 34:1035-9. 2007
- Experience with the levonorgestrel-releasing intrauterine system among HIV-infected womenPäivi Lehtovirta
Department of Obstetrics and Gynecology, University of Helsinki, SF 00029 Helsinki, Finland
Contraception 75:37-9. 2007..Yet, little is known about LNG-IUS use in HIV-infected women...
- Injectable progestin contraceptive use and risk of HIV infection in a South African family planning cohortImmo Kleinschmidt
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
Contraception 75:461-7. 2007....
- Hormonal contraception and risk of HIV-1 acquisition: results of a 10-year prospective studyLudo Lavreys
Departments of Epidemiology and Medicine, University of Washington, Seattle, WA, USA
AIDS 18:695-7. 2004
- Hormonal contraception and HIV prevalence in four African countriesPauline M Leclerc
Epidemiologie des Maladies Emergentes, Institut Pasteur, 25 rue du Docteur Roux, Paris, France
Contraception 77:371-6. 2008..The HIV seroprevalence among women aged 15-24 years was compared according to their pattern of contraceptive use in four African countries: Kenya, Lesotho, Malawi and Zimbabwe...
- The long-term actions of etonogestrel and levonorgestrel on decidualized and non-decidualized endometrium in a mouse model mimic some effects of progestogen-only contraceptives in womenNaomi B Morison
Prince Henry s Institute, PO Box 5152, Clayton, Victoria, Australia
Reproduction 133:309-21. 2007..MMP7 was primarily associated with tissue repair. Therefore, this model mimics some of the changes observed in endometria of women using p-only contraceptives and provides an opportunity for functional studies...
- Endometrial effects of intrauterine levonorgestrelAnja Guttinger
Division of Reproductive and Developmental Sciences, The Queen s Medical Research Institute, Centre for Reproductive Biology, The University of Edinburgh, EH16 4TJ Edinburgh, UK
Contraception 75:S93-8. 2007..Much remains to be determined about the mechanisms involved in suppression of menstruation, BTB episodes and the local endometrial environment with local LNG administration...
- Prospective clinical trials designed to assess the use of hormonal contraceptives and risk of HIV acquisitionCharles S Morrison
Family Health International, Research Triangle Park, NC, USA
J Acquir Immune Defic Syndr 38:S17-8. 2005
- Hormonal contraception and HIV-1 disease progression among postpartum Kenyan womenBarbra A Richardson
Department of Biostatistics, University of Washington, Seattle, WA 98194 2499, USA
AIDS 21:749-53. 2007..To assess the immediate and longer-term effects of the use of hormonal contraception on the progression of HIV-1 disease in postpartum women...
- Mifepristone, but not levonorgestrel, inhibits human blastocyst attachment to an in vitro endometrial three-dimensional cell culture modelP G L Lalitkumar
Division of Obstetrics and Gynecology, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital, S 171 76, Stockholm, Sweden
Hum Reprod 22:3031-7. 2007..This study investigates the effect of levonorgestrel and mifepristone on attachment of human embryos to an in vitro endometrial construct...
- Randomised comparative trial of thermal balloon ablation and levonorgestrel intrauterine system in patients with idiopathic menorrhagiaRobert W Shaw
Academic Division of Obstetrics and Gynaecology, University of Nottingham, Derby, UK
Aust N Z J Obstet Gynaecol 47:335-40. 2007....
- Superficial endometrial vascular fragility in Norplant users and in women with ovulatory dysfunctional uterine bleedingM Hickey
Department of Reproductive Science and Medicine, Imperial College School of Medicine at St Mary s, Norfolk Place W2 1PG, London, UK
Hum Reprod 15:1509-14. 2000..83, P = 0.01). There was no obvious relationship between subepithelial bleeding and circulating concentrations of oestradiol and progesterone...
- A longitudinal study of changes in endometrial microvascular density in Norplant implant usersM Hickey
Sydney Centre for Reproductive Health Research, Department of Obstetrics and Gynaecology, University of Sydney, Australia
Contraception 59:123-9. 1999..The findings suggest that the endometrial vasculature is profoundly altered in the early months of Norplant implant exposure when bleeding problems are most common...
- The effect upon the human vaginal histology of the long-term use of the injectable contraceptive Depo-ProveraL Bahamondes
Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas, UNICAMP, Campinas, Brazil
Contraception 62:23-7. 2000..In conclusion, the use of Depo-Provera between two and three years did not affect vaginal thinning of the epithelium, Langerhans cell count or maturation index...
- Health status function after treatment with thermal balloon endometrial ablation and levonorgestrel intrauterine system for idiopathic menorrhagia: a randomized studyWing Hung Tam
Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Hong Kong, SAR, China
Gynecol Obstet Invest 62:84-8. 2006..To compare patients' health status function after treatment with thermal balloon endometrial ablation (TBEA) and levonorgestrel intrauterine system (LNG-IUS) for idiopathic menorrhagia...
- Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093D Heather Watts
National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA
Contraception 77:84-90. 2008..We evaluated the safety and tolerability of depot medroxyprogesterone acetate (DMPA) among women on ARV...
- Spinal bone density in women using depot medroxyprogesterone contraceptionT Cundy
Department of Medicine, The Faculty of Medicine and Health Sciences, University of Auckland, New Zealand
Obstet Gynecol 92:569-73. 1998..To determine factors possibly associated with reduced bone density in women using the injectable contraceptive depot medroxyprogesterone acetate...
- Development of vaginal rings for sustained release of nonhormonal contraceptives and anti-HIV agentsYoung A Han
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, 515 East 71st Street, S 412, New York, NY 10021, USA
Contraception 76:132-8. 2007..Construction of vaginal rings to deliver nonhormonal contraceptives and 3'-azido-3'-deoxythymidine (AZT) as an anti-HIV agent and determination of their daily release and efficacy in vitro...
- The levonorgestrel-releasing intrauterine system (LNG-IUS) in HIV-infected women--effects on bleeding patterns, ovarian function and genital shedding of HIVOskari Heikinheimo
Department of Obstetrics and Gynaecology, University of Helsinki, Finland
Hum Reprod 21:2857-61. 2006..The levonorgestrel-releasing intrauterine system (LNG-IUS) is a highly effective contraceptive with additional health benefits. The objective of this study was to evaluate the effects of the LNG-IUS among HIV-infected women...
- Morphological and functional changes in human endometrium following intrauterine levonorgestrel deliveryR L Jones
Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
Hum Reprod 15:162-72. 2000....
- Endometrial vessel maturation in women exposed to levonorgestrel-releasing intrauterine system for a short or prolonged period of timeRavet Stéphanie
Laboratory of Tumor and Development Biology, Center of Experimental Cancer Research, University de Liège, Tour de Pathologie B23, Avenue de l Hopital, GIGA R, Sart Tilman, B 4000 Liege, Belgium
Hum Reprod 22:3084-91. 2007..The area, density and maturation of endometrial vessels were quantified in 19 endometrial biopsies of women with LNG-IUS and in 10 normally ovulating patients during mid-luteal phase...
- Hormonal contraceptive use and HIV-1 infection in a population-based cohort in Rakai, UgandaMohammed Kiddugavu
Rakai Project, Uganda Virus Research Institute, Entebbe, Uganda
AIDS 17:233-40. 2003..Hormonal contraceptives have been associated with increased risk of HIV acquisition...
- The role of tissue factor in regulating endometrial haemostasis: implications for progestin-only contraceptionC J Lockwood
Department of Obstetrics and Gynecology, New York University School of Medicine, NY 10016, USA
Hum Reprod 15:144-51. 2000....
- Abnormal uterine bleeding associated with hormonal contraceptionSarina Schrager
Department of Family Medicine, University of Wisconsin Medical School, Madison 53715, USA
Am Fam Physician 65:2073-80. 2002....
- Recent developments in hormone delivery systemsLee P Shulman
Department of Obstetrics and Gynecology, Feinberg School of Medicine at Northwestern University, Chicago, IL 60611, USA
Am J Obstet Gynecol 190:S39-48. 2004..Finally, hormonal implants that release low doses of progestins have been used for more than 30 years by a total of 10 million women, and easier-to-use implants will soon be available...
- Relationship between progesterone receptor level in endometrium and bleeding pattern in depot medroxyprogesterone acetate usersPichai Chotnopparatpattara
Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
J Med Assoc Thai 86:172-7. 2003..05). In conclusion, after a second dose of DMPA, subjects with amenorrhea had a higher stromal PR score than those with uterine bleeding...
- Effects of thrombin, hypoxia, and steroids on interleukin-8 expression in decidualized human endometrial stromal cells: implications for long-term progestin-only contraceptive-induced bleedingCharles J Lockwood
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Clin Endocrinol Metab 89:1467-75. 2004..However, LTPOC-induced hypoxia and excess thrombin generation enhance IL-8 expression in decidualized HESCs, thereby eliciting aberrant angiogenesis and inflammation that promote the onset of abnormal uterine bleeding...
- The Mirena levonorgestrel systemC Jay McGavigan
Department of Obstetrics and Gynecology, Southern General Hospital, South Glasgow University Hospitals NHS Trust, Govan, Glasgow, UK
Drugs Today (Barc) 39:973-84. 2003..Detailed counseling is crucial to explain this anticipated side effect in order to reduce unnecessary discontinuation of treatment...
- A three-dimensional study of endometrial microvessels in women using the contraceptive subdermal levonorgestrel implant system, norplantM Simbar
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, The University of Sydney, Sydney, NSW, 2006, Australia
Micron 35:589-95. 2004....
- A study of the capability of manufacturers of generic hormonal contraceptives in lower- and middle-income countriesPeter E Hall
Concept Foundation, Thailand Science Park, Pathumthani 12120, Thailand
Contraception 75:311-7. 2007..Studies were undertaken to assess the capability, competence and capacity of manufacturers of oral and injectable hormonal contraceptives in lower- and middle-income countries...
- Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodelingNatalie J Hannan
Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
J Clin Endocrinol Metab 89:6119-29. 2004..These findings support a number of roles for fractalkine in the endometrium, in the secretory phase, in early pregnancy, and when influenced by progestin-only contraceptives...
- Ovarian function with the contraceptive vaginal ring or an oral contraceptive: a randomized studyIngrid J M Duijkers
Dinox Medical Investigations, Groenewoudseweg 317, 6524 TX Nijmegen, The Netherlands
Hum Reprod 19:2668-73. 2004..The effects on ovarian function of the combined contraceptive vaginal ring NuvaRing and a combined oral contraceptive (COC) were compared...
- Managing drug-resistant essential menorrhagia without hysterectomyRitva Hurskainen
Department of Obstetrics and Gynecology, Hyvinkaa Hospital, Hospital District of Helsinki and Uusimaa, Sairaalank 1, 05850 Hyvinkaa, Finland
Best Pract Res Clin Obstet Gynaecol 20:681-94. 2006..However, second generation ablation techniques may offer better cost-effectiveness than the first generation techniques, but the evidence is insufficient...
- Hormonal contraception: recent advancesAnne Szarewski
Margaret Pyke Centre, London
J Fam Health Care 16:35-6. 2006
- Hormonal contraception and false-positive cervical cytology: is there an association?Anna V Hoekstra
Department of Obstetrics and Gynecology, Illinois Masonic Medical Center, Chicago, USA
J Low Genit Tract Dis 10:102-6. 2006..The aim of the study was to determine if use of hormonal contraception influences the false-positive rate of cervical cytology when compared with loop electrosurgical excision procedure or cervical biopsy specimens...
- Effect of etonogestrel subdermal contraceptive implant (Implanon) on liver function tests -- a randomized comparative study with Norplant implantsArijit Biswas
Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, 119074, Singapore
Contraception 70:379-82. 2004..The study aimed to assess the possible differences in effects of Implanon and Norplant implants on liver function over 2 years of use...
- Nondaily hormonal contraception: establishing a fit between product characteristics and patient preferencesJeffrey P Levine
Departments of Family Medicine and Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, 1 RWJ Place, CN19, New Brunswick, NJ 08903 0019, USA
J Fam Pract 53:904-13. 2004
- Conceivable sterilization: a constitutional analysis of a Norplant/Depo-Provera welfare conditionKimberly A Smith
Indiana University School of Law Bloomington, USA
Indiana Law J 77:389-418. 2002
- Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagiaA Kriplani
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
Int J Gynaecol Obstet 97:190-4. 2007..To evaluate the efficacy, acceptability, and possible side effects of a levonorgestrel-releasing intrauterine system for menorrhagia...
- Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girlsBarbara A Cromer
Department of Pediatrics, MetroHealth Medical Center, Cleveland, OH 44109, USA
J Adolesc Health 35:434-41. 2004....
- The effect of the levonorgestrel intrauterine system on uterine artery blood flow 1 year after insertionA Haberal
Department of Gynecology, S S K Ankara Maternity and Women s Health Teaching Hospital, Ankara, Turkey
Ultrasound Obstet Gynecol 27:316-9. 2006..To assess whether the morphological alterations of the endometrium induced by the levonorgestrel intrauterine system affect the uterine artery vasculature...
- Revisiting the intrauterine contraceptive device in adolescentsAlina Toma
Department of Obstetrics and Gynaecology, Queen s University, Kingston, Ontario, Canada
J Pediatr Adolesc Gynecol 19:291-6. 2006....
- Endometrial chemokines, uterine natural killer cells and mast cells in long-term users of the levonorgestrel-releasing intrauterine systemAlessandra Peloggia
Human Reproduction Unit, Department of Obstetrics and Gynaecology, School of Medicine, Universidade Estadual de Campinas UNICAMP, Campinas, SP, Brazil
Hum Reprod 21:1129-34. 2006..The objective was to assess endometrial chemokines in users of the levonorgestrel-releasing intrauterine system (LNG-IUS) and correlate them with leucocyte populations, uterine natural killer cells (uNK) and mast cells (MCs)...
- Effective use of hormonal contraceptives: Part II: Combined hormonal injectables, progestogen-only injectables and contraceptive implantsCamaryn E Chrisman
Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Contraception 73:125-33. 2006..Norplant implants left in place for up to seven completed years remained effective among women who weighed <70 kg at the time of implant insertion, but their effectiveness decreased among women weighing >or=70 kg...
- A prospective study of the forearm bone density of users of etonorgestrel- and levonorgestrel-releasing contraceptive implantsLuis Bahamondes
Human Reproduction Unit, Department of Obstetrics and Gynaecology, School of Medicine, Universidade Estadual de Campinas UNICAMP, 13084 971, Campinas, SP, Brazil
Hum Reprod 21:466-70. 2006..The aim of the study was to compare bone mineral density (BMD) before insertion and at 18 months of use of etonorgestrel- and levonorgestrel-releasing contraceptive implants...
- Five years' experience with a small intracervical/intrauterine levonorgestrel-releasing devicePaivi Pakarinen
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, 00029 HUS Helsinki, Finland
Contraception 72:342-5. 2005..A randomized study was performed to compare the efficacy, safety and acceptability of a new model of an intracervical/intrauterine contraceptive device (ICD) releasing 20 microg of levonorgestrel (LNG) per day...
- Levonorgestrel-releasing intrauterine system vs. transcervical endometrial resection for dysfunctional uterine bleedingB Gupta
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
Int J Gynaecol Obstet 95:261-6. 2006..To compare the acceptability, efficacy, adverse effects, and user satisfaction of a levonorgestrel intrauterine system (LNG-IUS) and transcervical resection of the endometrium (TCRE) for the treatment of dysfunctional uterine bleeding...
- Contraceptive and therapeutic effects of the levonorgestrel intrauterine system: an overviewJeffrey T Jensen
Department of Obstetrics and Gynecology, UHN 70, Oregon Health and Science University, 3181 Sam Jackson Park Road, Portland, OR 97239, USA
Obstet Gynecol Surv 60:604-12. 2005....
- Effect of Norplant contraceptive on the bones of Nigerian women as assessed by quantitative ultrasound and serum markers of bone turnoverDorothy J Vanderjagt
Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
Contraception 72:212-6. 2005..001). We conclude that although levonorgestrel contraceptive decreased overall bone turnover, it had no deleterious effect on the bone quality of women using Norplant implants for up to 4 years...
- [Weight variation in users of the levonorgestrel-releasing intrauterine system, of the copper IUD and of medroxyprogesterone acetate in Brazil]Daniela Angerame Yela
Departamento de Obstetricia e Ginecologia, Faculdade de Medicina, Universidade Estadual de Campinas UNICAMP, Campinas, Brazil
Rev Assoc Med Bras 52:32-6. 2006....
- What's new in adolescent contraception: what residents and teachers need to knowEduardo Lara-Torre
Kaza Medical Group, Milford, Delaware 19963, USA
J Pediatr Adolesc Gynecol 18:133-5. 2005
- Expression of vascular endothelial growth factors and their receptors in human endometrium from women experiencing abnormal bleeding patterns after prolonged use of a levonorgestrel-releasing intrauterine systemBjorn Moller
Department of Women s and Children s Health, Uppsala University, Sweden
Hum Reprod 20:1410-7. 2005..The aim of the study was to elucidate the possible association of these VEGF and receptors with bleeding disturbances among users of LNG-IUS...
- [Acceptability of intrauterine levonorgestrel delivery system (Mirena 52mg) after estrogen-progesterone oral contraception: results of a prospective multicentric study of 211 patients aged 25-35 years]P Collinet
clinique de gynécologie, Hopital Jeanne de Flandre, CHRU de Lille, 2, Avenue Oscar Lambret, 59037 Lille Cedex
J Gynecol Obstet Biol Reprod (Paris) 35:778-84. 2006..The purpose of this study was to evaluate patient satisfaction among young women during the first year of use of the intrauterine hormonal system...
- Relative cost effectiveness of Depo-Provera, Implanon, and Mirena in reversible long-term hormonal contraception in the UKSusan J Varney
CATALYST Health Economics Consultants, Northwood, Middlesex, UK
Pharmacoeconomics 22:1141-51. 2004....
- Benefit-risk assessment of the levonorgestrel intrauterine system in contraceptionTiina Backman
Department of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland
Drug Saf 27:1185-204. 2004..Thus, the benefits of the levonorgestrel-releasing IUS make it a very suitable method of contraception for most women...
- Weight changes in clients on hormonal contraceptives in Zaria, NigeriaSaadatu Sule
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
Afr J Reprod Health 9:92-100. 2005..This information will be beneficial in contraceptive counselling for clients in this environment and provide a baseline for further research...
- The combined contraceptive vaginal ring (NuvaRing) and lipid metabolism: a comparative studyM Tuppurainen
Laboratorio Gyne Oy, Kuopio, Finland
Contraception 69:389-94. 2004..These changes reflect the lower androgenicity of etonogestrel versus levonorgestrel and show that NuvaRing has a minimal effect on lipid profile...
- The local progestational effect of the levonorgestrel-releasing intrauterine system: a sonographic and Doppler flow studyY Zalel
Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel
Hum Reprod 17:2878-80. 2002..We aimed to evaluate the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) on the uterine vasculature and the endometrium...
- New developments in contraceptionL M Keder
College of Medicine, Department of Obstetrics and Gynecology, Ohio State University, Columbus, OH, USA
J Pediatr Adolesc Gynecol 15:179-81. 2002
- Successful pregnancy following insertion of a levonorgestrel-releasing intrauterine system in two infertile patients with complex atypical endometrial hyperplasiaXiujuan Qi
Department of Obstetrics and Gynecology, Qingdao University Medical School, Qingdao, PR China
Gynecol Obstet Invest 65:266-8. 2008..Histological morphology of endometrial samples after 6 months' exposure to LNG-IUS showed secretory or atrophic glands with decidualized stroma. Two healthy babies were born following ovulation induction after removal of the LNG-IUS...
- Clinical experience with Norplant subdermal implant system as long-term contraception during adolescenceE Cardamakis
Department of Obstetrics and Gynecology, University of Patras Medical School, University Hospital, Greece
Eur J Contracept Reprod Health Care 7:36-40. 2002..This study was undertaken to assess the efficacy, acceptability and side-effects of the Norplant (Leiras) contraceptive system during adolescence...
- Long-term effects of the levonorgestrel-releasing intrauterine system on serum lipids and the endometrium in breast cancer patients taking tamoxifenM D Kesim
Sisli Etfal Research and Training Hospital, 3th Obstetrics and Gynecology Clinic, Istanbul, Turkey
Climacteric 11:252-7. 2008..To investigate the long-term effects of a levonorgestrel-releasing intrauterine system on the endometrium and lipid profile of breast cancer patients taking tamoxifen...
- Hormonal effects of Depo-Provera in cervical smears: a comparison with Triphasil and postmenopausal effectsStamatina Kaptain
Department of Pathology, St Joseph s Wayne Hospital, Wayne, New Jersey, USA
Cancer 96:74-82. 2002....
- Recent developments in contraceptive implants at the Population CouncilIrving Sivin
Population Council, Center for Biomedical Research, New York, NY, USA
Contraception 65:113-9. 2002..The status and rationale of studies of a new Nestorone-releasing, single implant developed by the Population Council for a period of use of 2 years are presented...
- Implantable contraceptives for womenOlav Meirik
Instituto Chileno de Medicina Reproductiva, Santiago, Chile
Contraception 65:1-2. 2002
- Progestin-releasing intrauterine systemsT Luukkainen
Steroid Research Laboratory, Institute of Biomedicine, University of Helsinki, Helsinki, Finland
Semin Reprod Med 19:355-63. 2001..Users should be told that the LNG IUS does not prevent sexually transmitted infection, and therefore women at risk should also use condoms for their protection...
- Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia: a randomized, prospective, controlled clinical trial in female smokersT Kucuk
Department of Obstetrics and Gynecology, GATA School of Medicine, Ankara, Turkey
Clin Exp Obstet Gynecol 35:57-60. 2008..To compare the efficacy of three progestin regimens in perimenopausal menorrhagia...
- [Contraception with depot gestagens]D Koryntová
Gynekologicko porodnická klinika VFN a 1 LF UK, Praha
Ceska Gynekol 66:202-8. 2001..Summary of contraceptive implants and injectable contraceptives...
- Intrauterine contraception--what now and what next?J Guillebaud
Margaret Pyke Family Planning Centre, London, UK
Eur J Contracept Reprod Health Care 6:11-4. 2001..Regarding the inconvenience of the first weeks of light post-insertion bleeding and the early-phase low incidence ofsteroidal side-effects, forewarned is forearmed!..
- Effects of injectable or implantable progestin-only contraceptives on insulin-glucose metabolism and diabetes riskHenry S Kahn
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Diabetes Care 26:216-25. 2003..Additional research could help clarify whether exposure to injectable or implantable contraceptives leads to increased risk of type 2 diabetes and gestational diabetes in women with predisposing factors...
- Undiagnosed HIV in women attending a sexual health clinic for non-barrier methods of contraception. Two case studiesMartin Jones
Sexual Health, Eastbourne Sexual Health Clinic, Eastbourne Downs Primary Care Trust, Eastbourne, East Sussex, UK
J Fam Plann Reprod Health Care 29:31-2. 2003..It is suggested that providers of contraception are well placed to identify clients at high risk of HIV and to recommend HIV testing...
- Alternatives to oral regimens of contraceptionM Simon
Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Minerva Ginecol 59:271-86. 2007....
- Local levonorgestrel regulation of androgen receptor and 17beta-hydroxysteroid dehydrogenase type 2 expression in human endometriumKevin A Burton
Centre for Reproductive Biology, Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
Hum Reprod 18:2610-7. 2003....
- The levonorgestrel intrauterine system: a clinical perspective from the UKJohn Guillebaud
University College London and Margaret Pyke Centre, 73 Charlotte Street, London W1T 4PL, UK
Ann N Y Acad Sci 997:185-93. 2003..Regarding the admitted inconvenience of the first weeks of light postinsertion bleeding and the early phase low incidence of steroidal side effects: good counseling is paramount, since forewarned is forearmed!..
- Effects of levonorgestrel-releasing IUS and progesterone receptor modulator PRM CDB-2914 on uterine leiomyomasTakeshi Maruo
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, 650 0017, Japan
Contraception 75:S99-103. 2007..The cell type-specific action of CDB2914 on leiomyoma cells, without affecting the surrounding normal myometrial cells, is meaningful for understanding the usefulness of CDB2914 in the medical treatment of uterine myomas...
- Progress in contraception: new technologyEdward S Linn
Department of Ob Gyn, Lutheran General Hospital, Park Ridge, Illinois 60068 1174, USA
Int J Fertil Womens Med 48:182-91. 2003..This expanded menu of effective contraceptive options should help women find a method that suits their particular life style...
- Enlarged ovarian follicles in users of a levonorgestrel-releasing intrauterine system and contraceptive implantLuis Bahamondes
Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas, Campinas, SP, Brazil
J Reprod Med 48:637-40. 2003....
- The effect of a levonorgestrel-releasing intrauterine system on angiogenic growth factors in the endometriumB A Roopa
Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore
Hum Reprod 18:1809-19. 2003....
- [A randomized study comparing the efficacy and bleeding pattern of Implanon and Norplant hormonal contraceptive implant]Xiao Ying Yao
Department of Family Planning, Obstetric and Gynecology Hospital, Fudan University, Shanghai 200011, China
Zhonghua Fu Chan Ke Za Zhi 38:419-22. 2003..To compare the contraceptive efficacy, tolerability and bleeding patterns of Implanon and Norplant...
- Current treatment of dysfunctional uterine bleedingMarlies Y Bongers
Department of Obstetrics and Gynaecology, Maxima Medical Centre, P O Box 7777, 5500 MB Veldhoven, The Netherlands
Maturitas 47:159-74. 2004..We performed a review of the treatment modalities for dysfunctional uterine bleeding...
- A 5-year experience with Norplant implants in Thai womenJ Manonai
Department of Obstetrics and Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Int J Gynaecol Obstet 82:83-4. 2003
- The effects of the levonorgestrel intrauterine system (Mirena coil) on endometrial morphologyV Phillips
Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast BT12 6BL, Northern Ireland, UK
J Clin Pathol 56:305-7. 2003..The Mirena coil is a levonorgestrel releasing intrauterine device that is in widespread use. This study aims to document the endometrial morphology associated with this device...
- Effects of levonorgestrel-releasing intra-uterine system on the expression of vascular endothelial growth factor and adrenomedullin in the endometrium in adenomyosisJ B Laoag-Fernandez
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
Hum Reprod 18:694-9. 2003..Endometrial angiogenesis is believed to be regulated by angiogenic factors. The study aim was to evaluate the effects of LNg-IUS on vascular endothelial growth factor (VEGF) and adrenomedullin (AM) expression in the endometrium...
- Simultaneous use of a levonorgestrel intrauterine system and an etonogestrel subdermal implant for debilitating adolescent endometriosisMoamar Al-Jefout
Department of Obstetrics and Gynaecology, Queen Elizabeth II Research Institute for Mothers and Infants, University of Sydney, New South Wales, Australia
Aust N Z J Obstet Gynaecol 47:247-9. 2007....
- Toxicology of polymers for implant contraceptives for womenPrasad Venkatram Shastri
Department of Materials Science and Engineering and School of Medicine, University of Pennsylvania and Children s Hospital of Philadelphia, Abramson Research Center, Philadelphia, PA, USA
Contraception 65:9-13. 2002..However, any future implant development using these polymers should place an emphasis on processing parameters to minimize potential small molecule leachants and establish safety as a function of both site and duration of implantation...
- Parenteral administration of progestins for hormonal replacement therapyAnita Nath
Tietze fellow from the Population Council, New York, NY 10065, USA
Eur J Contracept Reprod Health Care 14:88-96. 2009..Although parenteral administration of progesterone or low-dose progestins should in theory be associated with fewer side-effects than oral therapy, the long-term safety of the newer systems warrants further evaluation...
- Preliminary evaluation of deslorelin, a GnRH agonist for contraception of the captive variable flying fox Pteropus hypomelanusLara C Metrione
White Oak Conservation Center, Yulee, FL 32097, USA
Contraception 78:336-45. 2008....
- Controversies in contraceptionSarah A B Pitts
Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Opin Pediatr 20:383-9. 2008..At times, these studies can be clarifying, but they can also raise new controversies and questions. It is important for providers to be aware of the emerging issues regarding contraceptive care for adolescent patients...
- A biodegradable levonorgestrel-releasing implant made of PCL/F68 compound as tested in rats and dogsGuilei Ma
The Tianjin Key Laboratory of Biomaterials, Institute of Biomedical Engineering, Peking Union Medical College and Chinese Academy of Medical Sciences, Nankai District, Tianjin 300192, China
Contraception 74:141-7. 2006..Our objective was to report preclinical studies on a biodegradable long-acting contraceptive implant...
- Systematic review of the effects of aromatase inhibitors on pain associated with endometriosisA Nawathe
Department of Obstetrics and Gynaecology, Birmingham Women s Hospital, University of Birmingham, Birmingham, UK corrected
BJOG 115:818-22. 2008..To assess the effects of aromatase inhibitors in women symptomatic of pain with endometriosis...
- Hormonal contraceptive use, pregnancy and parity, and the risk of cervical intraepithelial neoplasia 3 among oncogenic HPV DNA-positive women with equivocal or mildly abnormal cytologyPhilip E Castle
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Int J Cancer 117:1007-12. 2005....
- When 'emergency contraception' is neitherTimothy F Murphy
University of Illinois at Chicago, Chicago, IL 60612 7309, USA
Am J Bioeth 7:W7. 2007
- Birth control within reach: a national survey on women's attitudes toward and interest in pharmacy access to hormonal contraceptionSharon Cohen Landau
Pharmacy Access Partnership, Oakland, CA 94610, USA
Contraception 74:463-70. 2006....
- Modern management of abnormal uterine bleeding: the levonorgestrel intra-uterine systemDiana Mansour
Graingerville Clinic, Newcastle General Hospital, Newcastle upon Tyne, UK
Best Pract Res Clin Obstet Gynaecol 21:1007-21. 2007..This article will outline the development of the IUS, highlighting the most important recent areas of research covering its use to control menstrual blood loss and pain...
- Recent patent trends in the field of progesterone receptor agonists and modulatorsNorbert Schmees
Bayer Schering Pharma, Medicinal Chemistry, Muellerstrasse 178, 13353 Berlin, Germany
Expert Opin Ther Pat 19:1521-34. 2009..The interest for antagonists or selective progesterone receptor modulators (SPRMs) is growing. Recent reports on this class of compounds indicate that they could become the next generation of therapeutics in gynecological treatments...
- Oral contraceptives and liver hemangioma: a case-control studyOfer Gemer
Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel
Acta Obstet Gynecol Scand 83:1199-201. 2004..To study whether there is an epidemiological association between liver hemangiomas and oral contraception use, as may be suggested by clinical observations of liver hemangioma growth during pregnancy and under estrogen administration...
- CHEMICAL SYNTHESIS FACILITYBashir Kaskar; Fiscal Year: 2013..Health Branch (CRHB) supports research in the synthesis and testing of a broad spectrum of male and female contraceptive agents. Successful development of new contraceptive methods for men and women has been a goal for many decades...
- CHEMICAL SYNTHESIS FACILITYBashir Kaskar; Fiscal Year: 2012..Health Branch (CRHB) supports research in the synthesis and testing of a broad spectrum of male and female contraceptive agents. Successful development of new contraceptive methods for men and women has been a goal for many decades...
- MEDICINAL CHEMISTRY FACILITYGREGG PIOSKE; Fiscal Year: 2013..Development Branch (CDDB) support research in the synthesis and testing of a broad spectrum of male and female contraceptive agents. Successful development of new contraceptive methods for men and women has been a goal for many decades...
- Control of menstrual bleeding disturbances in womenIan Fraser; Fiscal Year: 2006..This study aims to explore these possibilities in large scale clinical studies, scientific study of vascular and molecular changes in endometrium and with the exploration of molecular mechanisms in mice. ..
- DEPO PROVERA AND BONE MINERAL DENSITY IN ADOLESCENTSBarbara Cromer; Fiscal Year: 2003..The statistical analysis will estimate the effect of DMPA on bone density while taking account of constant treatment discontinuation throughout the study period. ..
- Oral Contraceptive Use and Bone Density in Young WomenDelia Scholes; Fiscal Year: 2008..abstract_text> ..
- Ectopic Pregnancy: Assessing Long-Term Trends in Rates and Risk FactorsDelia Scholes; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Depo-provera & BMD: Continuing ObservationsM Clark; Fiscal Year: 2005..The longitudinal design will be continued, maintaining all methods and protocols employed in the parent study. ..
- PDE3 Inhibitors: Selective Blockers of Oocyte MaturationJeffrey Jensen; Fiscal Year: 2007..This approach is expected to provide a foundation for future Phase 1 trials of PDE3 inhibitors in humans. ..
- Stampidine: A Novel Broad-Spectrum Anti-HIV MicrobicideOSMOND D CRUZ; Fiscal Year: 2005..Specific Aims 1 and 2 may provide the foundation for the clinical development of STAMP in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
- Phase II SBIR: WHI-07: A Novel Dual-Function MicrobicideOSMOND D CRUZ; Fiscal Year: 2005....
- The effect of nonoxynol-9 on human endometriumJohn Jain; Fiscal Year: 2005..The results of this study will provide important preliminary information on the role of microbicides on endometrial toxicity and may help guide future research priorities. ..
- PHI-443: Novel Non-Spermicidal Anti-HIV MicrobicideOSMOND D CRUZ; Fiscal Year: 2003..Specific Aims 1 and 2 may provide the foundation for the clinical development of PHI-443 in Phase II studies as a safe, effective broad-spectrum anti-HIV microbicide without conception-inhibiting functions. ..
- METVAN: A Novel Anticancer AgentOSMOND D CRUZ; Fiscal Year: 2003..The knowledge gained from these studies described under Specific Aims 1-2 is expected to facilitate the design of innovative treatment regimens employing METVAN for metastatic breast cancer and brain tumor patients. ..
- NOVEL CONTRACEPTIVES WITH ANTI-HIV ACTIVITYOSMOND D CRUZ; Fiscal Year: 2001..The preclinical data on in vivo efficacies of WHI-05 and WHI-07 will be essential to further explore the utility of these novel drugs for clinical studies in human patients. ..
- Prophylactic Ibuprofen: Effect on IUD Continuation RatesDavid Hubacher; Fiscal Year: 2003..In the US, ibuprofen may help spur renewed interest in the most cost effective and efficacious reversible contraceptive method available. ..
- Vanadocenes as a New Class of Spermicidal DrugsOSMOND D CRUZ; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- PHI 346: A Novel Dual-Function MicrobicideOSMOND D CRUZ; Fiscal Year: 2003..Following successful completion of the Phase I in vivo efficacy studies, gel formulation of PHI-346 will be further explored as a vaginal dual-function microbicide in Phase II. ..
- FLP-102: Rationally Engineered Antiviral ProteinOSMOND D CRUZ; Fiscal Year: 2003..The preclinical data on FLP-102 will be essential to further explore the utility of this novel recombinant PAP mutant for Phase II. ..
- Effect of hormonal contraception on bone mineral densityAbbey Berenson; Fiscal Year: 2005..Ultimately, this study will determine which women, if any, are placed at increased risk of osteopenia or osteoporosis as a result of using these hormonal contraceptives during their reproductive years. ..
- Obesity, Oral Contraception and Ovarian SuppressionCarolyn Westhoff; Fiscal Year: 2007..This study will have very good power to detect clinically important differences. Results could directly and immediately affect contraceptive practice. ..
- Contraceptive Practice /Delivery -- Community PharmaciesJacqueline Gardner; Fiscal Year: 2005..abstract_text> ..
- RCT of a Novel Oral Contraceptive Initiation MethodCarolyn Westhoff; Fiscal Year: 2004..We will also assess dual method use for STD prevention in the study to adoption of and adherence to oral contraceptives. We will also assess dual method use for STD prevention in the study population. ..
- ESTIMATING EFFICACY OF A MEDICAL INTERVENTIONJames Trussell; Fiscal Year: 2001....
- Improving contraceptive use/practices among young womenMelissa Gilliam; Fiscal Year: 2008..unreadable] [unreadable]..
- Progesterone, GABA Receptors and Cell SurvivalMeharvan Singh; Fiscal Year: 2005..abstract_text> ..
- UNINTENDED PREGNANCY AND CONTRACEPTIVE EFFECTIVENESSSusheela Singh; Fiscal Year: 2004..abstract_text> ..
- Conspiracies, Perceived Discrimination & Sexual BehaviorSheryl Thorburn; Fiscal Year: 2003..Findings from this study will inform efforts to prevent HIV and other STDs, as well as unintended pregnancy, among African Americans nationally. ..
- Immunobiological Role of Fertilization Antigen(FA-1)RAJESH NAZ; Fiscal Year: 2007..unreadable] [unreadable]..
- Progestogen Inhibition of Ovarian Cancer Cell MetastasisWilliam Murdoch; Fiscal Year: 2003....
- A DIAGNOSTIC TEST TO ASSESS RISK ASSOCIATED WITH ANDROGEN THERAPYMeharvan Singh; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- The Role of Prolactin in the Etiology of Postmenopausal Breast CancerShelley Tworoger; Fiscal Year: 2008..This potentially may affect public health by increasing our understanding of how breast cancer develops, which in turn can lead to a better understanding of how to prevent this disease. [unreadable] [unreadable]..
- MITOCHONDRIAL DNA ANALYSIS IN CYCLIC VOMITING SYNDROMERichard Boles; Fiscal Year: 2002..An extensive amount of clinical and laboratory data will be collected in all patients, allowing for the comparison of CVS sufferers with and without mtDNA mutations. ..
- Clinical Relevance of Transient Nevirapine ResistanceLouise Kuhn; Fiscal Year: 2008..unreadable] [unreadable]..
- Pathogenesis of Essential Tremor: Cerebellar MetabolismElan Louis; Fiscal Year: 2008..abstract_text> ..
- Relationship Dynamics and Sexual Risk BehaviorsSANDY HARVEY; Fiscal Year: 2009..Findings will have significant implications for the design of interventions for reducing the risk of HIV infection among individuals in close relationships by addressing the dynamics of sexual partnerships. ..
- Antiretroviral Therapy and HIV-1 Infectivity in WomenRAYMOND SCOTT MCCLELLAND; Fiscal Year: 2010....
- WOMEN'S ACCEPTABILITY OF THE VAGINAL DIAPHRAGMSANDY HARVEY; Fiscal Year: 2002....
- HIV Protective Immunity and Perinatal ExposureLouise Kuhn; Fiscal Year: 2006..abstract_text> ..
- Mentored Investigator Award in Women's HealthLori Boardman; Fiscal Year: 2005....
- A Community Study of Infertility in Northern TanzaniaUlla Larsen; Fiscal Year: 2004..A basic protocol for the recommended treatment of infertility will be developed. 6. To analyze the social implications of infertility. 7. To assess the demographic implications of infertility. ..
- Oral contraceptives and cytochrome p450 inducersAnne Davis; Fiscal Year: 2006..unreadable] [unreadable]..
- WIH/Brown Epidemiology/Clinical Trials Training ProgramLori Boardman; Fiscal Year: 2006..This multidisciplinary program will provide a new cadre of ob/gyn investigators who will further the scientific database in reproductive health. ..
- RCT OF STEPPING STONES BEHAVIOURAL INTERVENTION FOR HIVRachel Jewkes; Fiscal Year: 2005..It will also seek to understand what are the barriers to behavior change and what strategies are used by which people to circumnavigate these. ..
- Identifying Services Changes to Improve Contraceptive U*Jennifer Frost; Fiscal Year: 2005..By identifying gaps in knowledge and effective intervention models, it will also stimulate new research and intervention development and evaluation. ..
- COLON CANCER SURVIVORS--MEDICATIONS & RISK OF RECURRENCEChristine Johnson; Fiscal Year: 2004..Using automated pharmacy data, the timing of use and exposure to NSAIDs and HRT will be analyzed among cancer survivors, along with potentially confounding variables, in relation to these outcomes. ..
- Mammographic Densities: In the Pathway to Breast Cancer?KARIN ROSENBLATT; Fiscal Year: 2005..abstract_text> ..
- Polybrominated Biphenyls and Cancer RiskKARIN ROSENBLATT; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORSDavid Archer; Fiscal Year: 2006..If successful, DOX treatment could become an important adjuvant for treatment of this and possibly other inflammatory disorders effecting reproductive tract tissues. ..
- VULVODYNIA PREVALENCE AND EFFICACY OF 4 INTERVENTIONSGloria Bachmann; Fiscal Year: 2004..Our ultimate goal is to share findings from this and related research with the broadest cross-spectrum of women that we can. ..
- Membrane Androgen Receptors in NeuroprotectionMeharvan Singh; Fiscal Year: 2007..unreadable] [unreadable]..
- St. John's Wort Effects on LevonorgestrelPatricia Murphy; Fiscal Year: 2006..The study protocol will be refined for use in future studies of levonorgestrel and other emergency contraceptive regimens. ..
- HORMONAL CONTROL OF THE FEMALE REPRODUCTIVE TRACTRobert Brenner; Fiscal Year: 2004..The VEGF family and MMPs during menstrual induction. 2. VEFG-HGF interactions in MMP regulation. 3. KGF-VEGF interactions in spiral artery growth. 4. HGF and VEGF antagonists during menstruation. ..
- Increased Access to Emergency Contraceptive PillsElizabeth Raymond; Fiscal Year: 2004..These secondary analyses should help explain the primary biologic outcomes and should be useful in the development of counseling messages and service protocols in the future. ..
- ORAL CONTRACEPTIVES FOR DYSMENORRHEA IN ADOLESCENT GIRLSAnne Davis; Fiscal Year: 2002..Given their efficacy in pregnancy prevention, safety, and non-contraceptive health benefits, COC may be an ideal therapy for primary dysmenorrhea in adolescent girls. ..
- A RCT of LNG-IUD vs. DMPA for young postpartum womenNancy Stanwood; Fiscal Year: 2005..Such a study could provide evidence for the safe and effective use of LNG-IUD in young postpartum women, leading to fewer unintended pregnancies. ..
- Early Environmental Hygiene and Pediatric AtopyChristine C Johnson; Fiscal Year: 2006..Further, working with Dr. F. Martinez, we will use the established repository of biospecimens to develop molecular epidemiologic studies of genetic-environmental risk factors. ..
- Effects of Hypericum Perforatum on Oral ContraceptivesPatricia Murphy; Fiscal Year: 2002..A concurrent aim is the development and refinement of a methodology for evaluating the risk of ovulation and unintended pregnancy from use of other herbs or medications during oral contraceptive use. ..