fructans

Summary

Summary: Polysaccharides composed of D-fructose units.

Top Publications

  1. ncbi Roles of the fructans from leaf sheaths and from the elongating leaf bases in the regrowth following defoliation of Lolium perenne L
    A Morvan-Bertrand
    , IRBA, , France
    Planta 213:109-20. 2001
  2. ncbi Molecular characterization of sucrose:sucrose 1-fructosyltransferase and sucrose:fructan 6-fructosyltransferase associated with fructan accumulation in winter wheat during cold hardening
    Akira Kawakami
    National Agricultural Research Center for Hokkaido Region, Hitsujigaoka, Sapporo 062 8555, Japan
    Biosci Biotechnol Biochem 66:2297-305. 2002
  3. pmc Properties of fructan:fructan 1-fructosyltransferases from chicory and globe thistle, two Asteracean plants storing greatly different types of inulin
    Rudy Vergauwen
    K U Leuven, Laboratory for Developmental Biology, 3001 Leuven, Belgium
    Plant Physiol 133:391-401. 2003
  4. ncbi Can dietary fructans lower serum glucose?
    Nana K A Bonsu
    Program in Gerontology, University of Regina, Saskatchewan, Canada
    J Diabetes 3:58-66. 2011
  5. ncbi Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice
    Evelyne M Dewulf
    Louvain Drug Research Institute, Metabolism and Nutrition Research Group, LDRI, Universite Catholique de Louvain, 1200 Brussels, Belgium
    J Nutr Biochem 22:712-22. 2011
  6. pmc Fructan and its relationship to abiotic stress tolerance in plants
    David P Livingston
    USDA and North Carolina State University, 840 Method Road, Unit 3, Raleigh, NC 27695, USA
    Cell Mol Life Sci 66:2007-23. 2009
  7. pmc Fructans, but not the sucrosyl-galactosides, raffinose and loliose, are affected by drought stress in perennial ryegrass
    Véronique Amiard
    Unité Mixte de Recherche Institut National de la Recherche Agronomique Université de Caen Basse Normandie, Laboratoire de Physiologie et Biochimie Végétales, Institut de Recherche en Biologie Appliquée, Universite, 14032 Caen Cedex, France
    Plant Physiol 132:2218-29. 2003
  8. ncbi Inulin-type fructans: functional food ingredients
    Marcel B Roberfroid
    Universite Catholique de Louvain, B 1348 Louvain la Neuve, Belgium
    J Nutr 137:2493S-2502S. 2007
  9. ncbi Molecular structures of fructans from Agave tequilana Weber var. azul
    Mercedes G Lopez
    Departamento de Biotecnologia y Bioquimica, Centro de Investigacion y de Estudios Avanzados del IPN, Unidad Irapuato, Apartado Postal 629, Irapuato, Gto, 36500 Mexico
    J Agric Food Chem 51:7835-40. 2003
  10. ncbi Plant fructans in stress environments: emerging concepts and future prospects
    Ravi Valluru
    Institute for Crop Production and Grassland Research, University of Hohenheim, D 70599 Stuttgart, Germany
    J Exp Bot 59:2905-16. 2008

Research Grants

Detail Information

Publications229 found, 100 shown here

  1. ncbi Roles of the fructans from leaf sheaths and from the elongating leaf bases in the regrowth following defoliation of Lolium perenne L
    A Morvan-Bertrand
    , IRBA, , France
    Planta 213:109-20. 2001
    ..cv. Bravo) during the first 48 h of regrowth showed that fructans from elongating leaf bases were hydrolysed first whereas fructans in mature leaf sheaths were degraded only after ..
  2. ncbi Molecular characterization of sucrose:sucrose 1-fructosyltransferase and sucrose:fructan 6-fructosyltransferase associated with fructan accumulation in winter wheat during cold hardening
    Akira Kawakami
    National Agricultural Research Center for Hokkaido Region, Hitsujigaoka, Sapporo 062 8555, Japan
    Biosci Biotechnol Biochem 66:2297-305. 2002
    ..Our results showed that Wft1 and Wft2 were important in fructan accumulation during cold hardening of winter wheat...
  3. pmc Properties of fructan:fructan 1-fructosyltransferases from chicory and globe thistle, two Asteracean plants storing greatly different types of inulin
    Rudy Vergauwen
    K U Leuven, Laboratory for Developmental Biology, 3001 Leuven, Belgium
    Plant Physiol 133:391-401. 2003
    ..Some species such as artichoke (Cynara scolymus) and globe thistle (Echinops ritro) store fructans with a considerably higher degree of polymerization than the one observed in chicory (Cichorium intybus) and ..
  4. ncbi Can dietary fructans lower serum glucose?
    Nana K A Bonsu
    Program in Gerontology, University of Regina, Saskatchewan, Canada
    J Diabetes 3:58-66. 2011
    Convincing evidence indicates that the consumption of inulin-type fructans, inulin, and oligofructose has beneficial effects on blood glucose changes in animal models, although data in humans have been considered equivocal...
  5. ncbi Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARγ-related adipogenesis in the white adipose tissue of high-fat diet-fed mice
    Evelyne M Dewulf
    Louvain Drug Research Institute, Metabolism and Nutrition Research Group, LDRI, Universite Catholique de Louvain, 1200 Brussels, Belgium
    J Nutr Biochem 22:712-22. 2011
    Inulin-type fructans (ITF) are nondigestible/fermentable carbohydrates which are able - through the modification of the gut microbiota - to counteract high-fat (HF) diet-induced obesity, endotoxemia and related-metabolic alterations...
  6. pmc Fructan and its relationship to abiotic stress tolerance in plants
    David P Livingston
    USDA and North Carolina State University, 840 Method Road, Unit 3, Raleigh, NC 27695, USA
    Cell Mol Life Sci 66:2007-23. 2009
    ..These experiments indicate that besides an indirect effect of supplying tissues with hexose sugars, fructan has a direct protective effect that can be demonstrated by both model systems and genetic transformation...
  7. pmc Fructans, but not the sucrosyl-galactosides, raffinose and loliose, are affected by drought stress in perennial ryegrass
    Véronique Amiard
    Unité Mixte de Recherche Institut National de la Recherche Agronomique Université de Caen Basse Normandie, Laboratoire de Physiologie et Biochimie Végétales, Institut de Recherche en Biologie Appliquée, Universite, 14032 Caen Cedex, France
    Plant Physiol 132:2218-29. 2003
    ..1,6) alpha-D-Glc (1,2) beta-D-Fru], in drought tolerance of perennial ryegrass and to compare it with that of fructans. To that end, the loliose biosynthetic pathway was first established and shown to operate by a UDP-Gal: sucrose (..
  8. ncbi Inulin-type fructans: functional food ingredients
    Marcel B Roberfroid
    Universite Catholique de Louvain, B 1348 Louvain la Neuve, Belgium
    J Nutr 137:2493S-2502S. 2007
    ..The term inulin-type fructans covers all beta(2<--1) linear fructans including native inulin (DP 2-60, DP(av) = 12), oligofructose (DP 2-8, ..
  9. ncbi Molecular structures of fructans from Agave tequilana Weber var. azul
    Mercedes G Lopez
    Departamento de Biotecnologia y Bioquimica, Centro de Investigacion y de Estudios Avanzados del IPN, Unidad Irapuato, Apartado Postal 629, Irapuato, Gto, 36500 Mexico
    J Agric Food Chem 51:7835-40. 2003
    Agave plants utilize crassulacean acid metabolism (CAM) for CO(2) fixation. Fructans are the principal photosynthetic products generated by agave plants...
  10. ncbi Plant fructans in stress environments: emerging concepts and future prospects
    Ravi Valluru
    Institute for Crop Production and Grassland Research, University of Hohenheim, D 70599 Stuttgart, Germany
    J Exp Bot 59:2905-16. 2008
    ..b>Fructans are fructose-based polymers synthesized from sucrose by fructosyltransferases (FTs)...
  11. ncbi Carbohydrate partitioning between upper and lower regions of the crown in oat and rye during cold acclimation and freezing
    D P Livingston
    USDA and North Carolina State University, Unit 3, Raleigh, NC 27695, USA
    Cryobiology 52:200-8. 2006
    ..Results suggest that to understand how carbohydrates relate to freezing tolerance, regions of the crown that endure freezing stress differently should be compared...
  12. pmc Pp6-FEH1 encodes an enzyme for degradation of highly polymerized levan and is transcriptionally induced by defoliation in timothy (Phleum pratense L.)
    Ken ihi Tamura
    National Agricultural Research Center for Hokkaido Region, Hitsujigaoka 1, Toyohira, Sapporo 062 8555, Japan
    J Exp Bot 62:3421-31. 2011
    ..In temperate grass species accumulating fructans, defoliation induces the activity of a fructan exohydrolase (FEH) that degrades fructans to serve as a carbon ..
  13. ncbi Contribution of alginate and levan production to biofilm formation by Pseudomonas syringae
    Heike Laue
    Molecular Microbial Ecology Group, BioCentrum DTU, Technical University of Denmark, DK 2800 Lyngby, Denmark
    Microbiology 152:2909-18. 2006
    ..syringae derivatives. Production of the as yet uncharacterized additional EPS might be more important for biofilm formation than the syntheses of levan and alginate...
  14. pmc Plants modify biological processes to ensure survival following carbon depletion: a Lolium perenne model
    Julia M Lee
    DairyNZ Ltd, Hamilton, New Zealand
    PLoS ONE 5:e12306. 2010
    ..In addition, many transcriptomic experiments have typically been undertaken under laboratory conditions; therefore, long-term acclimation strategies that plants use in natural environments are not well understood...
  15. ncbi Dietary fructans and serum triacylglycerols: a meta-analysis of randomized controlled trials
    Furio Brighenti
    Department of Public Health, University of Parma, Parma, Italy
    J Nutr 137:2552S-2556S. 2007
    Convincing evidence indicates that the intake of inulin-type fructans, inulin and oligofructose, has beneficial effects on blood lipid changes in animals, although data in humans have been considered contradictory...
  16. ncbi Production of long-chain levan by a sacC insertional mutant from Bacillus subtilis 327UH
    Toshio Shida
    Department of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, Ueda, Nagano, Japan
    Biosci Biotechnol Biochem 66:1555-8. 2002
    ..After transformation of 327UH with a levanase-deficient 168SC (sacC::Cm(r)) chromosomal DNA, a Cm(r) transformant 327UHSC (sacC::Cm(r) degSU(Hy)) produced 3 times longer levan than that of the wild type...
  17. pmc Towards understanding vacuolar antioxidant mechanisms: a role for fructans?
    Darin Peshev
    KU Leuven, Laboratory of Molecular Plant Biology, Kasteelpark Arenberg 31, Leuven, Belgium
    J Exp Bot 64:1025-38. 2013
    ..Based on these and previous findings, a working model is proposed describing the putative radical reactions involving fructans and secondary metabolites at the inner side of the tonoplast and in the vacuolar lumen.
  18. ncbi Overview of experimental data on reduction of colorectal cancer risk by inulin-type fructans
    Beatrice L Pool-Zobel
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University, Jena, Germany
    J Nutr 137:2580S-2584S. 2007
    ..The responsible carcinogens cause mutations or enhance cell growth. Inulin-type fructans may counteract the effects via their gut flora-mediated fermentation products in vitro and in vivo...
  19. ncbi Quantification of fructans, galacto-oligosacharides and other short-chain carbohydrates in processed grains and cereals
    J R Biesiekierski
    Department of Medicine, Monash University, Box Hill, Victoria, Australia
    J Hum Nutr Diet 24:154-76. 2011
    ..The prebiotics best studied are fructans [fructooligosaccharides (FOS), inulin] and galactooligosaccharides (GOS)...
  20. pmc In vitro kinetic analysis of fermentation of prebiotic inulin-type fructans by Bifidobacterium species reveals four different phenotypes
    Gwen Falony
    Research Group of Industrial Microbiology and Food Biotechnology, Department of Applied Biological Sciences and Engineering, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Appl Environ Microbiol 75:454-61. 2009
    ..These variations indicate niche-specific adaptation of bifidobacteria and could have in vivo implications on the strain specificity of the stimulatory effect of inulin-type fructans on bifidobacteria.
  21. ncbi Fructan and free fructose content of common Australian vegetables and fruit
    Jane G Muir
    Monash University, Department of Medicine, Box Hill Hospital, Victoria 3128, Australia
    J Agric Food Chem 55:6619-27. 2007
    b>Fructans are not digested in the small intestines of humans. While many health benefits have been attributed to these carbohydrates, they can cause gastrointestinal symptoms in some individuals...
  22. ncbi Fructans interact strongly with model membranes
    R A Demel
    Department Biochemistry of Membranes, Centre for Biomembranes and Lipid Enzymology, Utrecht University, Padualaan 8, NL 3584 CH Utrecht, Netherlands
    Biochim Biophys Acta 1375:36-42. 1998
    Bacterial fructans with a high degree of polymerisation cause a very large increase in surface pressure of lipid monolayers at the air-water interface with a broad range of lipids, including phosphatidylethanolamine and several types of ..
  23. ncbi Contribution of Erwinia amylovora exopolysaccharides amylovoran and levan to biofilm formation: implications in pathogenicity
    Jessica M Koczan
    Department of Plant Biology, Michigan State University, East Lansing 48824, USA
    Phytopathology 99:1237-44. 2009
    ..These results demonstrate that biofilm formation plays a critical role in the pathogenesis of E. amylovora...
  24. ncbi Studies with inulin-type fructans on intestinal infections, permeability, and inflammation
    Francisco Guarner
    Digestive System Research Unit, University Hospital Vall d Hebron, CIBERehd, Barcelona, Spain
    J Nutr 137:2568S-2571S. 2007
    Symbiosis between host and gut bacteria can be optimized by prebiotics. Inulin-type fructans have been shown to improve the microbial balance of the intestinal ecosystem by stimulating the growth of bifidobacteria and lactobacilli...
  25. ncbi Set up of a new in vitro model to study dietary fructans fermentation in formula-fed babies
    Gwenaelle Le Blay
    Laboratory of Food Biotechnology, Institute of Food Science and Nutrition, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich, Switzerland
    Br J Nutr 103:403-11. 2010
    ..simulating the proximal colon of a formula-fed baby was developed and used to test the effects of known prebiotic fructans. Intestinal fermentation, based on a previously developed colonic fermentation model, using a new feeding medium ..
  26. ncbi In vitro comparison of the prebiotic effects of two inulin-type fructans
    Anna Pompei
    Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro 6, 40100 Bologna, Italy
    Anaerobe 14:280-6. 2008
    ..05) compared to the control. Significant changes in the pH and levels of ammonia with both inulin-type fructans were observed, as well as higher levels of acetic, lactic and formic acids (P< or =0.05)...
  27. ncbi Microbial fructosyltransferases and the role of fructans
    M L Velázquez-Hernández
    Centro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolas de Hidalgo, Michoacan, Mexico
    J Appl Microbiol 106:1763-78. 2009
    ..Microbial fructans are involved in conferring resistance to environmental stress such as water deprivation, nutrient assimilation, ..
  28. ncbi High levan accumulation in transgenic tobacco plants expressing the Gluconacetobacter diazotrophicus levansucrase gene
    Alexander Banguela
    Laboratorio Interacciones Planta Microorganismo, Centro de Ingenieria Genetica y Biotecnologia CIGB, Habana, Cuba
    J Biotechnol 154:93-8. 2011
    ..of onion sucrose:sucrose 1-fructosyltransferase (1-SST) in tobacco, a crop that does not naturally produce fructans. In the transgenic plants, levan with degree of polymerization above 10(4) fructosyl units was detected in leaves,..
  29. ncbi Short-term effect of bedtime consumption of fermented milk supplemented with calcium, inulin-type fructans and caseinphosphopeptides on bone metabolism in healthy, postmenopausal women
    Berit Adolphi
    Department of Physiology and Biochemistry of Nutrition, Max Rubner Institut MRI, Federal Research Institute of Nutrition and Food, Hermann Weigmann Strasse 1, 24103, Kiel, Germany
    Eur J Nutr 48:45-53. 2009
    ..Milk products are good sources of calcium and their consumption may reduce bone resorption and thus contribute to prevent bone loss...
  30. pmc Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis?
    Tita Ritsema
    Botanisches Institut der Universität Basel, Zurich Basel Plant Science Center, Basel, Switzerland
    PLoS ONE 4:e6605. 2009
    ..The results lead us to infer a central role for small GTPases in sugar signaling...
  31. ncbi Importance of pre-anthesis anther sink strength for maintenance of grain number during reproductive stage water stress in wheat
    Xuemei Ji
    CSIRO Plant Industry, Canberra, Australian Capital Territory 2601, Australia
    Plant Cell Environ 33:926-42. 2010
    ....
  32. pmc Towards a better understanding of the generation of fructan structure diversity in plants: molecular and functional characterization of a sucrose:fructan 6-fructosyltransferase (6-SFT) cDNA from perennial ryegrass (Lolium perenne)
    Bertrand Lasseur
    UMR INRA UCBN 950 EVA Ecophysiologie Végétale, Agronomie and nutritions NCS, Universite de Caen, Esplanade de la Paix, 14032 Caen Cedex, France
    J Exp Bot 62:1871-85. 2011
    The main storage compounds in Lolium perenne are fructans with prevailing β(2-6) linkages. A cDNA library of L. perenne was screened using Poa secunda sucrose:fructan 6-fructosyltransferase (6-SFT) as a probe...
  33. ncbi Enhanced levan production using chitin-binding domain fused levansucrase immobilized on chitin beads
    Chung Jen Chiang
    Department of Medical Laboratory Science and Biotechnology, China Medical University, No 91, Hsueh Shih Road, Taichung, 40402, Taiwan
    Appl Microbiol Biotechnol 82:445-51. 2009
    ..It is apparent that this approach offers a promising way for levan production by Z. mobilis levansucrase immobilized on chitin beads...
  34. ncbi Sequential production of two biopolymers-levan and poly-ε-lysine by microbial fermentation
    Ing Lung Shih
    Department of Environmental Engineering, Da Yeh University, Changhua, Taiwan
    Bioresour Technol 102:3966-9. 2011
    ..The process of using remnant (waste) from levan fermentation for the second biopolymer (ε-PL) production is unprecedented and the products obtained are environmental-friendly...
  35. ncbi Ryegrass leaf fructan synthesis is oxygen dependent and abolished by endomembrane inhibitors
    Andrew J Cairns
    Institute of Biological Environmental and Rural Sciences, Aberystwyth University, Gogerddan SY233EB, UK
    New Phytol 180:832-40. 2008
    ..It was shown that the results were inconsistent with a vacuolar site for fructan synthesis. Six inhibitors of endomembrane function were shown to abolish fructan synthesis in vivo...
  36. ncbi Effect of the dietary polyphenolic fraction of chicory root, peel, seed and leaf extracts on caecal fermentation and blood parameters in rats fed diets containing prebiotic fructans
    Jerzy Juśkiewicz
    Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, 10 Tuwima Street, Olsztyn, Poland
    Br J Nutr 105:710-20. 2011
    ..was to examine the physiological response of growing rats to a dietary combination of prebiotic chicory fructans, with polyphenols originating from different parts of the chicory plant, i.e. roots, root peels, seeds and leaves...
  37. ncbi Digestive tolerance of inulin-type fructans: a double-blind, placebo-controlled, cross-over, dose-ranging, randomized study in healthy volunteers
    Jacques Bruhwyler
    Squarepoint Pointcarré sprl, Ecaussinnes, Belgium
    Int J Food Sci Nutr 60:165-75. 2009
    Similar to other indigestible carbohydrates or dietary fibres, a consumption of too large quantities of inulin-type fructans may cause some digestive problems.
  38. ncbi Comparison of native or reformulated chicory fructans, or non-purified chicory, on rat cecal fermentation and mineral metabolism
    Christian Demigne
    UMR1019, Unité Nutrition Humaine, INRA, Centre Clermont Ferrand Theix, 63122, St Genes Champanelle, France
    Eur J Nutr 47:366-74. 2008
    ..inulin ((NAT)Inulin) or a reformulated inulin ((REF)Inulin, based on a combination of short- and long chain fructans) or dehydrated chicory...
  39. ncbi Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects
    T Van De Wiele
    Laboratory Microbial Ecology and Technology LabMET, Ghent University, Ghent, Belgium
    J Appl Microbiol 102:452-60. 2007
    We assessed to what extent fructans of different degrees of polymerization (DP) differ in their prebiotic effectiveness towards in vitro microbial communities from the proximal and distal colon.
  40. ncbi Crystallization and preliminary X-ray diffraction study of fructan 1-exohydrolase IIa from Cichorium intybus
    Maureen Verhaest
    Laboratorium voor Analytische Chemie en Medicinale Fysicochemie, Faculteit Farmaceutische Wetenschappen, K U Leuven, E Van Evenstraat 4, B 3000 Leuven, Belgium
    Acta Crystallogr D Biol Crystallogr 60:553-4. 2004
    ..83, b = 139.83, c = 181.94 A. Calculation of the Matthews coefficient indicates there to be two or three molecules in the asymmetric unit. Synchrotron radiation was used to collect a complete native data set to a resolution of 2.35 A...
  41. ncbi Isolation, structural elucidation and immunomodulatory activity of fructans from aged garlic extract
    Puthanapura M Chandrashekar
    Department of Biochemistry and Nutrition, Central Food Technological Research Institute Council of Scientific and Industrial Research Laboratory, Mysore, Karnataka State, India
    Phytochemistry 72:255-64. 2011
    ..AGE is also known to contain fructans; the amount of fructans in AGE represents a small fraction (0.22%) of the total fructans in raw garlic...
  42. ncbi Prebiotic capacity of inulin-type fructans
    Sofia Kolida
    Food Microbial Sciences Unit, Department of Food Biosciences, The University of Reading, Reading, UK
    J Nutr 137:2503S-2506S. 2007
    ..In vitro and in vivo evidence has accumulated to confirm the prebiotic effects of inulin-derived fructans.
  43. ncbi Long-term administration of inulin-type fructans has no significant lipid-lowering effect in normolipidemic humans
    Fabien Forcheron
    INSERM U 499, Faculté RTH Laennec, IFR 62, Universite Claude Bernard Lyon, 69008 Lyon, France
    Metabolism 56:1093-8. 2007
    Short-term studies have shown that the addition to diet of inulin-type fructans, a nondigestible carbohydrate, may have a plasma lipid-lowering effect in humans...
  44. ncbi Linear ion trap MS(n) of enzymatically synthesized 13C-labeled fructans revealing differentiating fragmentation patterns of β (1-2) and β (1-6) fructans and providing a tool for oligosaccharide identification in complex mixtures
    Scott Harrison
    AgResearch, Grasslands Research Center, Palmerston North, New Zealand
    Anal Chem 84:1540-8. 2012
    b>Fructans are polymeric carbohydrates, which play important roles as plant reserve carbohydrates and stress protectants, and are beneficial for human health and animal production...
  45. ncbi Kinetic study of the thermal hydrolysis of Agave salmiana for mezcal production
    M J Garcia-Soto
    Departamento de Ingeniería Química Bioquímica, Instituto Tecnológico de Celaya, Avenida Tecnológico s n, Celaya, Guanajuato 38010, México
    J Agric Food Chem 59:7333-40. 2011
    The kinetics of the thermal hydrolysis of the fructans of Agave salmiana were determined during the cooking step of mezcal production in a pilot autoclave...
  46. ncbi In vitro fermentation profiles, gas production rates, and microbiota modulation as affected by certain fructans, galactooligosaccharides, and polydextrose
    David C Hernot
    University of Illinois, Department of Animal Sciences, 1207 West Gregory Drive, Urbana, Illinois 61801, USA
    J Agric Food Chem 57:1354-61. 2009
    ..Mixing short- and long-chain oligosaccharides attenuated short-chain oligosaccharide fermentation rate and extent. This study provides new information on the fermentation characteristics of some oligosaccharides used in human nutrition...
  47. pmc Unexpected presence of graminan- and levan-type fructans in the evergreen frost-hardy eudicot Pachysandra terminalis (Buxaceae): purification, cloning, and functional analysis of a 6-SST/6-SFT enzyme
    Wim Van den Ende
    Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, KU Leuven, B 3001 Leuven, Belgium
    Plant Physiol 155:603-14. 2011
    About 15% of flowering plants accumulate fructans. Inulin-type fructans with β(2,1) fructosyl linkages typically accumulate in the core eudicot families (e.g...
  48. ncbi Fructan accumulation and transcription of candidate genes during cold acclimation in three varieties of Poa pratensis
    R Shyama Prasad Rao
    Aarhus University, Faculty of Agricultural Sciences, Department of Genetics and Biotechnology, Forsøgsvej 1, Slagelse, Denmark
    J Plant Physiol 168:344-51. 2011
    Poa pratensis, a type species for the grass family (Poaceae), is an important cool season grass that accumulates fructans as a polysaccharide reserve...
  49. ncbi [Systematic review of the effects of inulin-type fructans on blood lipid profiles: a meta-analysis]
    Ting Wu
    Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China
    Wei Sheng Yan Jiu 39:172-6. 2010
    To conduct a systematic review on the efficacy of inulin-type fructans on lowering blood lipids, randomized controlled intervention trials on the analysis of plasma total cholesterol and triacylglycerol resulted from the treatment of ..
  50. ncbi High dietary intake of prebiotic inulin-type fructans in the prehistoric Chihuahuan Desert
    Jeff D Leach
    Paleobiotics Laboratory, 2401 Burgundy Suite 7, New Orleans, LA 70117, USA
    Br J Nutr 103:1558-61. 2010
    ..in the northern Chihuahuan Desert reveal intensive utilisation of desert plants that store prebiotic inulin-type fructans as the primary carbohydrate...
  51. ncbi Enzymatic hydrolysis of fructans in the tequila production process
    Angela Avila-Fernández
    Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico
    J Agric Food Chem 57:5578-85. 2009
    ..of reserve carbohydrates in most plant-derived alcoholic beverage processes carried out with enzymes, agave fructans in tequila production have traditionally been transformed to fermentable sugars through acid thermal hydrolysis...
  52. ncbi Levan (beta-2, 6-fructan), a major fraction of fermented soybean mucilage, displays immunostimulating properties via Toll-like receptor 4 signalling: induction of interleukin-12 production and suppression of T-helper type 2 response and immunoglobulin E p
    Q Xu
    Central Research Institute, Mizkan Group Co Ltd, Handa, Japan
    Clin Exp Allergy 36:94-101. 2006
    ..However, the formulations previously examined were not chemically pure, and this is a major limitation for elucidation of the molecular mechanisms for their activities...
  53. pmc Structural and kinetic analysis of Schwanniomyces occidentalis invertase reveals a new oligomerization pattern and the role of its supplementary domain in substrate binding
    Miguel Alvaro-Benito
    Centro de Biologia Molecular Severo Ochoa, Departamento de Biologia Molecular, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 285:13930-41. 2010
    ..This highlights the essential function that oligomerization plays in substrate specificity and assigns, for the first time, a direct catalytic role to the supplementary domain of a GH32 enzyme...
  54. ncbi Determination of the structure and degree of polymerisation of fructans from Echinacea purpurea roots
    Maren Wack
    Pharmaceutical Institute, Department of Pharmaceutical Biology, Christian Albrechts University of Kiel, Gutenbergstr 76, D 24118 Kiel, Germany
    Carbohydr Res 341:1147-53. 2006
    Highly water soluble fructans have been isolated from Echinacea purpurea (L.) Moench. roots by hot water extraction and precipitation at three different ethanol concentrations (80% v/v, 60% v/v and 40% v/v)...
  55. ncbi Molecular characterization of a putative sucrose:fructan 6-fructosyltransferase (6-SFT) of the cold-resistant Patagonian grass Bromus pictus associated with fructan accumulation under low temperatures
    F del Viso
    Instituto de Biotecnologia, CICVyA, Instituto Nacional de Tecnologia Agropecuaria INTA, Castelar, 1686, Hurlingham, Buenos Aires, Argentina
    Plant Cell Physiol 50:489-503. 2009
    b>Fructans are fructose polymers synthesized from sucrose in the plant vacuole. They represent short- and long-term carbohydrate reserves and have been associated with abiotic stress tolerance in graminean species...
  56. ncbi Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence
    Susan J Shepherd
    Department of Gastroenterology and Monash University Department of Medicine, Box Hill Hospital, Victoria, Australia
    Clin Gastroenterol Hepatol 6:765-71. 2008
    ....
  57. pmc Lactobacillus paracasei subsp. paracasei 8700:2 degrades inulin-type fructans exhibiting different degrees of polymerization
    Lefteris Makras
    Research Group of Industrial Microbiology, Fermentation Technology and Downstream Processing IMDO, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Appl Environ Microbiol 71:6531-7. 2005
    Ten strains of lactobacilli were assessed for their capacity to degrade inulin-type fructans, which are well-known prebiotics. Both oligofructose and inulin were tested...
  58. ncbi Water-soluble carbohydrates and fructan structure patterns from Agave and Dasylirion species
    N Alejandra Mancilla-Margalli
    Departamento de Biotecnologia y Bioquimica, Centro de Investigacion y de Estudios Avanzados del IPN, Campus Guanajuato, Apartado Postal 629, Irapuato, Gto, 36500 Mexico
    J Agric Food Chem 54:7832-9. 2006
    b>Fructans, storage carbohydrates with beta-fructofuranosyl linkages, are found in approximately 15% of higher plants...
  59. ncbi Transgenic tobacco plants accumulating osmolytes show reduced oxidative damage under freezing stress
    Daniela Parvanova
    Abiotic Stress Tolerance and Echophysiology, AgroBioInstitute, Institute of Cryobiology and Food Technology, Sofia, Bulgaria
    Plant Physiol Biochem 42:57-63. 2004
    ..Our lines and model system could serve as a good prerequisite for additional studies to gain further insights into the complex role of osmoprotectants in freezing tolerance...
  60. ncbi Coordinated expression of functionally diverse fructosyltransferase genes is associated with fructan accumulation in response to low temperature in perennial ryegrass
    Hiroshi Hisano
    Research Faculty of Agriculture, Hokkaido University, Sapporo 060 8589, Japan
    New Phytol 178:766-80. 2008
    ..Thus at least two different patterns of gene expression have developed during the evolution of functionally diverse FT genes, which are associated in a coordinated way with fructan synthesis in a cold environment...
  61. ncbi Current data with inulin-type fructans and calcium, targeting bone health in adults
    Veronique Coxam
    Unité de Nutrition Humaine UMR1019, Equipe Alimentation Squelette et Métabolismes INRA Theix, Saint Genes Champanelle, France
    J Nutr 137:2527S-2533S. 2007
    ..and this process may be susceptible to dietary manipulation by fermentable substrates, especially inulin-type fructans. Inulin-type fructans can modulate calcium absorption because they are resistant to hydrolysis by mammalian ..
  62. ncbi Improved fructan accumulation in perennial ryegrass transformed with the onion fructosyltransferase genes 1-SST and 6G-FFT
    Gitte Gadegaard
    Department of Biosystems, Risoe National Laboratory, Roskilde, Denmark
    J Plant Physiol 165:1214-25. 2008
    ..Further, the high fructan content was stable during the growth period, whereas the fructan content in an elite variety, marketed as a high sugar variety, dropped rapidly after reaching its maximum and subsequently remained low...
  63. pmc The effect of fructan on membrane lipid organization and dynamics in the dry state
    Ingrid J Vereyken
    Department Biochemistry of Membranes, CBLE, Institute of Biomembranes, Utrecht University, The Netherlands
    Biophys J 84:3759-66. 2003
    b>Fructans are a group of fructose-based oligo- and polysaccharides, which appear to be involved in membrane preservation during dehydration by interacting with the membrane lipids...
  64. ncbi Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis
    Umang Munjal
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 102:663-71. 2009
    ..Moreover, since early adenoma cells were found to be more sensitive, this may have important implications for chemoprevention when translated to the in vivo situation, because survival of early transformed cells could be reduced...
  65. ncbi Experimental evidences on the potential of prebiotic fructans to reduce the risk of colon cancer
    B Pool-Zobel
    Institute for Nutrition, Department of Nutritional Toxicology, Friedrich Schiller University Jena, Germany
    Br J Nutr 87:S273-81. 2002
    Inulin is extracted from the chicory root. It is a set of fructans with its monomers linked by means of beta(2-1) bonds...
  66. ncbi Fructans insert between the headgroups of phospholipids
    I J Vereyken
    Department of Biochemistry of Membranes, CBLE, Institute of Biomembranes, Utrecht University, The Netherlands
    Biochim Biophys Acta 1510:307-20. 2001
    b>Fructans are polysaccharides consisting of one glucose unit and two or more fructose units. It was hypothesized that fructans play a role in drought tolerance in plants by interacting directly with the membrane...
  67. ncbi Fructosyltransferase mutants specify a function for the beta-fructosidase motif of the sucrose-binding box in specifying the fructan type synthesized
    Tita Ritsema
    Department of Molecular Plant Physiology, University Utrecht, Padualaan 8, CH, The Netherlands
    Plant Mol Biol 54:853-63. 2004
    The onion fructosyltransferase fructan:fructan 6G-fructosyltransferase (6G-FFT) synthesizes fructans of the inulin neo-series using 1-kestose as a substrate...
  68. pmc Cloning and functional analysis of a fructosyltransferase cDNA for synthesis of highly polymerized levans in timothy (Phleum pratense L.)
    Ken ichi Tamura
    National Agricultural Research Center for Hokkaido Region, Hitsujigaoka 1, Toyohira, Sapporo 062 8555, Japan
    J Exp Bot 60:893-905. 2009
    Variation in the structures of plant fructans and their degree of polymerization (DP) can be explained as the result of diverse combinations of fructosyltransferases (FTs) with different properties...
  69. ncbi Molecular and functional characterization of a cDNA encoding fructan:fructan 6G-fructosyltransferase (6G-FFT)/fructan:fructan 1-fructosyltransferase (1-FFT) from perennial ryegrass (Lolium perenne L.)
    Bertrand Lasseur
    UMR INRA UCN 950 EVA Ecophysiologie Végétale, Agronomie et Nutritions NCS, Universite de Caen, Esplanade de la Paix, F 14032 Caen Cedex, France
    J Exp Bot 57:2719-34. 2006
    b>Fructans are the main storage compound in Lolium perenne. To account for the prevailing neokestose-based fructan synthesis in this species, a cDNA library of L...
  70. ncbi Cloning, gene mapping, and functional analysis of a fructan 1-exohydrolase (1-FEH) from Lolium perenne implicated in fructan synthesis rather than in fructan mobilization
    Jérémy Lothier
    UMR INRA UCBN 950 EVA Ecophysiologie Végétale, Agronomie et Nutritions NCS, Universite de Caen, Esplanade de la Paix, 14032 Caen Cedex, France
    J Exp Bot 58:1969-83. 2007
    b>Fructans, which are beta-(2,1) and/or beta-(2,6) linked polymers of fructose, are important storage carbohydrates in many plants. They are mobilized via fructan exohydrolases (FEHs)...
  71. ncbi Purification, cloning and functional characterization of a fructan 6-exohydrolase from wheat (Triticum aestivum L.)
    Liesbet Van Riet
    Laboratory of Molecular Plant Physiology, Institute of Botany and Microbiology, K U Leuven, Kasteelpark Arenberg 31, B 3001 Leuven, Belgium
    J Exp Bot 57:213-23. 2006
    b>Fructans, beta2-1 and/or beta2-6 linked polymers of fructose, are produced by fructosyltransferases (FTs) from sucrose. They are important storage carbohydrates in many plants...
  72. ncbi Dietary fructans, but not cellulose, decrease triglyceride accumulation in the liver of obese Zucker fa/fa rats
    Catherine Daubioul
    Unit of Pharmacokinetics, Metabolism, Nutrition and Toxicology, 7369 School of Pharmacy, Universite Catholique de Louvain, B 1200 Brussels, Belgium
    J Nutr 132:967-73. 2002
    ..The high fermentation of fructans compared with cellulose was reflected by greater cecal contents and by a twofold greater propionate concentration ..
  73. ncbi Molecular cloning and functional analysis of a novel 6&1-FEH from wheat (Triticum aestivum L.) preferentially degrading small graminans like bifurcose
    Akira Kawakami
    National Agricultural Research Center for Hokkaido Region, Hitsujigaoka, Sapporo, 062 8555, Japan
    Gene 358:93-101. 2005
    Like barley and other cereals, wheat (Triticum aestivum L.) accumulates branched graminan-type fructans containing both beta-(2,1) and beta-(2,6) fructosyl linkages, mainly with a quite low degree of polymerization (DP)...
  74. ncbi selective production and characterization of levan by Bacillus subtilis (Natto) Takahashi
    Ing Lung Shih
    Department of Environmental Engineering, Da Yeh University, Chang Hwa, Taiwan
    J Agric Food Chem 53:8211-5. 2005
    ..subtilis strains tested and, as previously reported, it produced the highest yield of levan in the least time (21 h) under the common cultivation condition...
  75. pmc Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops
    Gareth S Catchpole
    Max Planck Institute for Molecular Plant Physiology, D 14424 Golm, Germany
    Proc Natl Acad Sci U S A 102:14458-62. 2005
    ..We show that, apart from targeted changes, these GM potatoes in this study appear substantially equivalent to traditional cultivars...
  76. ncbi A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents
    Steven A Abrams
    US Department of Agriculture Agricultural Research Service, Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX 77030, USA
    Am J Clin Nutr 82:471-6. 2005
    Short-term studies in adolescents have generally shown an enhancement of calcium absorption by inulin-type fructans (prebiotics)...
  77. ncbi Cloning and functional analysis of a high DP fructan:fructan 1-fructosyl transferase from Echinops ritro (Asteraceae): comparison of the native and recombinant enzymes
    Wim Van den Ende
    KU Leuven, Laboratory of Molecular Plant Physiology, Kasteelpark Arenberg 31, B 3001 Leuven, Belgium
    J Exp Bot 57:775-89. 2006
    Inulin-type fructans are the simplest and most studied fructans and have become increasingly popular as prebiotic health-improving compounds...
  78. ncbi Effect of water stress on proline accumulation of genetically modified potatoes (Solanum tuberosum L.) generating fructans
    Gabriele Knipp
    University Institute of Crop Science and Plant Breeding I, Justus Liebig University Giessen Germany
    J Plant Physiol 163:392-7. 2006
    ..the effect of water stress on the accumulation of proline in the leaves of transgenic potato lines generating fructans. The results of the series of bifactorial experiments in 2002 and 2003 indicated an increase of the proline level ..
  79. ncbi Fructans from oat and rye: composition and effects on membrane stability during drying
    Dirk K Hincha
    Max Planck Institut fur Molekulare Pflanzenphysiologie, D 14424 Potsdam, Germany
    Biochim Biophys Acta 1768:1611-9. 2007
    b>Fructans have been implicated in the abiotic stress tolerance of many plant species, including grasses and cereals...
  80. ncbi Chromium(III) propionate and dietary fructans supplementation stimulate erythrocyte glucose uptake and beta-oxidation in lymphocytes of rats
    Tomasz Kuryl
    Department of Physiological Sciences, Veterinary Medicine Faculty, Agricultural University, 02 787 Warsaw, Poland
    Biol Trace Elem Res 114:237-48. 2006
    The study describes the effects of 10-wk dietary supplementation with fructans (inulin and oligofructose, 5% and 10%, respectively) as well as the biomimetic Cr(III) propionate complex (0...
  81. ncbi The rice genome encodes two vacuolar invertases with fructan exohydrolase activity but lacks the related fructan biosynthesis genes of the Pooideae
    Xuemei Ji
    Plant Breeding, Genetics and Biochemistry Division, International Rice Research Institute, DAPO Box 7777, Metro Manila, Philippines
    New Phytol 173:50-62. 2007
    b>Fructans are believed to contribute to cold and drought tolerance in several plant families (Poaceae, Asparagaceae and Asteraceae), but it is not clear why the ability to accumulate these polymers is found in some genera (e.g...
  82. pmc The effect of fructan on the phospholipid organization in the dry state
    Ingrid J Vereyken
    Department Biochemistry of Membranes, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands
    Biophys J 85:3058-65. 2003
    b>Fructans, a family of oligo- and polyfructoses, are implicated to play a drought-protecting role in plants. Inulin-type fructan is able to preserve the membrane barrier during dehydration...
  83. ncbi Developing fructan-synthesizing capability in a plant invertase via mutations in the sucrose-binding box
    Tita Ritsema
    Zurich Basel Plant Science Center, Botanisches Institut der Universität Basel, Hebelstrasse 1, 4056 Basel, Switzerland
    Plant J 48:228-37. 2006
    b>Fructans are fructose polymers that are synthesized from sucrose by fructosyltransferases. Fructosyltransferases are present in unrelated plant families suggesting a polyphyletic origin for their transglycosylation activity...
  84. ncbi Hydrolase and fructosyltransferase activities implicated in the accumulation of different chain size fructans in three Asteraceae species
    Nair M Itaya
    Seção de Fisiologia e Bioquímica de Plantas, Instituto de Botânica, Caixa Postal 3005, 01061 970 São Paulo, SP, Brazil
    Plant Physiol Biochem 45:647-56. 2007
    b>Fructans are widely distributed in Asteraceae from floras with seasonal growth and are thought to be involved in drought and freezing tolerance, in addition to storage function...
  85. ncbi Calcium is essential for fructan synthesis induction mediated by sucrose in wheat
    Giselle Martínez-Noël
    Centro de Investigaciones Biologicas, Fundación para Investigaciones Biológicas Aplicadas FIBA, Vieytes 3103, 7600 Mar del Plata, Argentina
    Planta 225:183-91. 2006
    ..Our results support the hypothesis that calcium is a component of the sucrose signaling pathway that leads to the induction of fructan synthesis...
  86. pmc Coculture fermentations of Bifidobacterium species and Bacteroides thetaiotaomicron reveal a mechanistic insight into the prebiotic effect of inulin-type fructans
    Gwen Falony
    Research Group of Industrial Microbiology and Food Biotechnology IMDO, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Appl Environ Microbiol 75:2312-9. 2009
    ..subgroups within the large-intestinal Bifidobacterium population will be stimulated by different groups of prebiotic inulin-type fructans, a variation that could be reflected in differences concerning their health-promoting effects.
  87. ncbi Fructan:fructan 1-fructosyltransferase, a key enzyme for biosynthesis of graminan oligomers in hardened wheat
    Akira Kawakami
    Laboratory of Fungal Disease, Department of Plant Pathology, National Agricultural Research Center, Kannondai, Tsukuba, Ibaraki 305 8666, Japan
    Planta 223:90-104. 2005
    b>Fructans play important roles not only as a carbon source for survival under persistent snow cover but also as agents that protect against various stresses in overwintering plants...
  88. ncbi Effects of fructans-type prebiotics on lipid metabolism
    N M Delzenne
    UCL Université Catholique de Louvain, School of Pharmacy, Brussels
    Am J Clin Nutr 73:456S-458S. 2001
    ..Oligofructose, which is a mixture of nondigestible and fermentable fructans, can decrease triacylglycerol in VLDL when given to rats...
  89. ncbi Fate of fructose supplied to leaf sheaths after defoliation of Lolium perenne L.: assessment by 13C-fructose labelling
    Véronique Amiard
    UMR INRA UCBN Physiologie et Biochimie Végétales, IRBA, Universite de Caen, Esplanade de la Paix, F 14032 Caen Cedex, France
    J Exp Bot 54:1231-43. 2003
    The role of fructans from leaf sheaths for the refoliation of Lolium perenne after severe defoliation was assessed by following the fate of (13)C-fructose supplied to leaf sheaths at the time of defoliation...
  90. pmc Structural requirements of the fructan-lipid interaction
    Ingrid J Vereyken
    Department Biochemistry of Membranes, Center for Biomembranes, Lipids, and Enzymology, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Biophys J 84:3147-54. 2003
    b>Fructans are a group of fructose-based oligo- and polysaccharides. They are proposed to be involved in membrane protection of plants during dehydration...
  91. ncbi Fructans in the diet cause alterations of intestinal mucosal architecture, released mucins and mucosa-associated bifidobacteria in gnotobiotic rats
    Brigitta Kleessen
    German Institute of Human Nutrition DIfE Potsdam Rehbrucke, D 14558 Bergholz Rehbrücke, Germany
    Br J Nutr 89:597-606. 2003
    The effects of fructans in the diet on the mucosal morphometry (height of villi, depth of the crypts, number of goblet cells), the thickness of the epithelial mucus layer and the histochemical composition of intestinal mucosubstances in ..
  92. ncbi Plant fructan exohydrolases: a role in signaling and defense?
    Wim Van den Ende
    KU Leuven, Institute of Botany and Microbiology, Laboratory of Molecular Plant Physiology, Kasteelpark Arenberg 31, B 3001 Heverlee, Belgium
    Trends Plant Sci 9:523-8. 2004
    b>Fructans are fructose oligomers and polymers synthesized by a small number of plant and bacterial species and mainly function as reserve carbohydrates...
  93. ncbi Protein kinase and phosphatase activities are involved in fructan synthesis initiation mediated by sugars
    G M Noël
    Centro de Investigaciones Biologicas, Fundacións para Investigaciones Biológicas Aplicadas FIBA, Mar del Plata, Argentina
    Planta 213:640-6. 2001
    ..Our data indicate that protein kinase and protein phosphatase activities take part in the chain of events that intervenes in the induction of fructan synthesis by sugars...
  94. pmc Disaccharide-mediated regulation of sucrose:fructan-6-fructosyltransferase, a key enzyme of fructan synthesis in barley leaves
    J Muller
    Botanisches Institut der Universität Basel, Hebelstrasse 1, CH 4056 Basel, Switzerland
    Plant Physiol 123:265-74. 2000
    ....
  95. ncbi Engineering fructan metabolism in plants
    Tita Ritsema
    Molecular Plant Physiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    J Plant Physiol 160:811-20. 2003
    b>Fructans, or polyfructosylsucroses, are storage carbohydrates present in many higher plants. They are also considered healthy food ingredients...
  96. ncbi Specific effects of fructo- and gluco-oligosaccharides in the preservation of liposomes during drying
    Dirk K Hincha
    Max Planck Institut fur Molekulare Pflanzenphysiologie, D 14424 Potsdam, Germany
    Glycobiology 12:103-10. 2002
    ..However, it has been unclear whether fructans have properties that make them better protectants for cellular structures than other sugars...
  97. ncbi Differences in chain length distribution of inulin from Cynara scolymus and Helianthus tuberosus are reflected in a transient plant expression system using the respective 1-FFT cDNAs
    E M Hellwege
    Max Planck Institut fur Molekulare Pflanzenphysiologie, Golm, Germany
    FEBS Lett 427:25-8. 1998
    ..23, whereas parallel experiments performed using a 1-FFT cDNA from Jerusalem artichoke led to the production of fructans with a DP of up to only 12...
  98. ncbi Cloning of the fructan biosynthesis pathway of Jerusalem artichoke
    I M van der Meer
    DLO Centre for Plant Breeding and Reproduction Research CPRO DLO, Department of Cell Biology, Wageningen, The Netherlands
    Plant J 15:489-500. 1998
    ..In tubers, the spatial and developmental expression correlates with the accumulation of fructans. Using the 1-sst and 1-fft cDNAs, chimeric genes were constructed driven by the CaMV 35S promoter...
  99. ncbi Fructan biosynthesis in transgenic plants
    Andrew J Cairns
    Plant Breeding Department, Institute of Grassland and Environmental Research, Plas Gogerddan, Aberystwyth SY23 3EB, Wales, UK
    J Exp Bot 54:549-67. 2003
    ..This implies a direct influence of the intracellular environment on the capacity for polymerization of fructosyltransferases and may have implications for the mechanism of natural fructan polymerization in vivo...
  100. ncbi Pet food and feed applications of inulin, oligofructose and other oligosaccharides
    E A Flickinger
    Department of Animal Sciences, University of Illinois, 132 Animal Sciences Laboratory, 1207 W Gregory Drive, Urbana 61801, USA
    Br J Nutr 87:S297-300. 2002
    ..Research to date indicates positive effects of prebiotics on health status and performance of companion animals, livestock, and poultry...
  101. ncbi Dietary fructans
    M B Roberfroid
    Universite Catholique de Louvain, Department of Pharmaceutical Sciences, Brussels, Belgium
    Annu Rev Nutr 18:117-43. 1998
    ..This review focuses on the fate of inulin-type fructans (namely native chicory inulin, oligofructose produced by the partial enzymatic hydrolysis of chicory inulin, and ..

Research Grants6

  1. Impact of Diet on Intestinal Microbiota-Host Dynamics
    Justin Sonnenburg; Fiscal Year: 2013
    ..function of an operon conserved in Bacteroides required for use of abundant dietary plant polysaccharides called fructans;(ii) determine how model microbiotas composed of bacterial species with differing relative abilities to utilize ..
  2. Genomic and metabolomic foundations of human-microbial symbiosis in the gut
    JEFFREY IVAN GORDON; Fiscal Year: 2013
    ..species to be sequenced);(ii) colonize GF mice fed standard polysaccharide-rich chow, a chow enriched for fructans, or a high fat Western diet with B. theta and/or M...
  3. GENETICS OF ORAL MICROFLORA
    FRANCIS MACRINA; Fiscal Year: 2000
    ..containing epitopes from the glucan-binding protein; (3) to determine that sucrose-derived glucans, and not fructans, are endocarditis virulence determinants and that attachment of these polymers to bacteria via GTF and glucan ..
  4. Regulation of Streptococcus mutans Virulence by covR/S
    Grace Spatafora; Fiscal Year: 2003
    ..covR/S homologs in the regulation of fructosyltransferases (ftf) that mediate the sucrose-dependent production of fructans necessary for bacterial adherence to the tooth pellicle. Since S...
  5. STREPTOCOCCUS MUTANS GENES IMPORTANT TO VIRULENCE
    Michael Hudson; Fiscal Year: 1992
    ..The second aim of the work is to understand how the synthesis and breakdown of fructans (fructose polymers) contribute to S. mutans pathogenicity...
  6. Effects of Natural Agents with Fluoride on Caries
    Hyun Koo; Fiscal Year: 2004
    ....