Genomes and Genes
biocompatible coated materials
Summary: Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
Publications237 found, 100 shown here
- Anode glow discharge plasma treatment enhances calcium phosphate adsorption onto titanium platesY Shibata
Department of Oral Biomaterials and Technology, Showa University School of Dentistry, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8555, Japan
J Dent Res 81:841-4. 2002..In addition, calcium phosphate was not nucleated on the specimen with GDP-. We conclude that GDP+ is more suitable for biomineralization on titanium...
- Endothelial progenitor cell capture by stents coated with antibody against CD34: the HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth-First In Man) RegistryJiro Aoki
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 45:1574-9. 2005..This study was designed to evaluate whether rapid endothelialization of stainless steel stents with a functional endothelium prevents stent thrombosis and reduces the restenotic process...
- Staphylococcus aureus adhesion to titanium oxide surfaces coated with non-functionalized and peptide-functionalized poly(L-lysine)-grafted-poly(ethylene glycol) copolymersL G Harris
AO Research Institute, Interface Biology, Clavadelerstrasse, CH7270 Davos Platz, Switzerland
Biomaterials 25:4135-48. 2004..aureus adhesion, resulting in a selective biointeraction pattern that may be useful for applications in the area of osteosynthesis, orthopaedic and dental implantology...
- Electronic manipulation of DNA, proteins, and nanoparticles for potential circuit assemblyLifeng Zheng
Electrical Engineering and Computer Science, University of California, Irvine, CA 92697 2625, USA
Biosens Bioelectron 20:606-19. 2004..The technique of simultaneously measuring resistance while using dielectrophoresis to trap nanoscale objects should find broad applicability...
- Nano-structured polymers enhance bladder smooth muscle cell functionAnil Thapa
Department of Biomedical Engineering, Purdue University, West Lafayette, IN 47907 1296, USA
Biomaterials 24:2915-26. 2003..This claim is supported by the fact that cell number was enhanced on nano-structured compared to conventional PLGA and PU once chemistry changes were eliminated using casting techniques...
- Mechanism(s) of increased vascular cell adhesion on nanostructured poly(lactic-co-glycolic acid) filmsDerick C Miller
Weldon School of Biomedical Engineering, Purdue University, 500 Central Drive, West Lafayette, IN 47907 2022, USA
J Biomed Mater Res A 73:476-84. 2005..In this manner, this study continues to provide evidence for the promise of nanostructured PLGA in vascular tissue engineering applications...
- Study of antirestenosis with the BiodivYsio dexamethasone-eluting stent (STRIDE): a first-in-human multicenter pilot trialXiaoshun Liu
Department of Cardiology, University Hospitals Leuven, Leuven, Belgium
Catheter Cardiovasc Interv 60:172-8; discussion 179. 2003..0.60 +/- 0.55 mm, P < 0.07, and 26.86 +/- 14 vs. 38.40 +/- 16%, P < 0.02). This study demonstrated the feasibility and safety of the implantation of a dexamethasone-eluting stent and its effect on in-stent neointimal hyperplasia...
- Deposition of silver nanoparticles on titanium surface for antibacterial effectLiao Juan
State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, PR China
Int J Nanomedicine 5:261-7. 2010..These data suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial...
- Restenosis following implantation of bare metal coronary stents: pathophysiology and pathways involved in the vascular response to injuryNeal A Scott
Camino Cardiovascular Associates, 525 South Drive, Suite 107, Mountain View, CA 94040, USA
Adv Drug Deliv Rev 58:358-76. 2006..Although preliminary data suggest that the use of drug-eluting stents may be effective, only intracoronary radiation has shown consistent efficacy in randomized trials...
- Biomimetic apatite formation on chemically treated titaniumLenka Jonásová
Department of Materials Science III, University of Erlangen Nuremberg, Martensstrasse 5, Erlangen 91058, Germany
Biomaterials 25:1187-94. 2004..The treatment of titanium by acid etching in HCl and subsequently in NaOH is a suitable method for providing the metal implant with bone-bonding ability...
- Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary angiography and three-dimensional intravascular ultrasound studyJ E Sousa
Institute Dante Pazzanese of Cardiology, Sao Paulo, Brazil
Circulation 103:192-5. 2001..Restenosis remains an important limitation of interventional cardiology. Therefore, we aimed to determine the safety and efficacy of sirolimus (a cell-cycle inhibitor)-coated BX Velocity stents...
- Preparation and characterization of rapamycin-loaded PLGA coating stentC J Pan
Key Lab for Advanced Technologies of Materials of Ministry of Education, Southwest Jiaotong University, Chengdu 610031, China
J Mater Sci Mater Med 18:2193-8. 2007..Take into these results account, this novel rapamycin-eluting may be a good candidate to resolve in-stent restenosis...
- Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vitronectinT J Webster
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
Tissue Eng 7:291-301. 2001..These events, namely, enhanced vitronectin adsorption, comformation, and bioactivity, may explain the increased osteoblast adhesion on nanophase alumina...
- Vascular response to sirolimus-eluting stents delivered with a nonaggressive implantation technique: comparison of intravascular ultrasound results from the multicenter, randomized E-SIRIUS, and SIRIUS trialsRainer Hoffmann
Medical Clinic I, University Hospital Aachen, Aachen, Germany
Catheter Cardiovasc Interv 66:499-506. 2005....
- Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy)Paolo Ortolani
Institute of Cardiology, Policlinico S Orsola, University of Bologna, Bologna, Italy
Am J Cardiol 96:1393-8. 2005..In conclusion, in diabetics with small coronary arteries, SES implantation significantly reduces the incidence of the 8-month angiographic restenosis rate compared with BMSs...
- Early failure of precoated femoral components in primary total hip arthroplastyAlvin Ong
Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4283, USA
J Bone Joint Surg Am 84:786-92. 2002..Reports differ as to whether this step has increased or decreased the rate of failure. This study was designed to evaluate this issue...
- Drug-eluting stent thrombosis: results from a pooled analysis including 10 randomized studiesRaul Moreno
Division of Interventional Cardiology, Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain
J Am Coll Cardiol 45:954-9. 2005..We compared the risk of stent thrombosis (ST) after drug-eluting stents (DES) versus bare-metal stents (BMS), and tested the hypothesis that the risk of DES thrombosis is related to stent length...
- Paclitaxel coating reduces in-stent intimal hyperplasia in human coronary arteries: a serial volumetric intravascular ultrasound analysis from the Asian Paclitaxel-Eluting Stent Clinical Trial (ASPECT)Myeong Ki Hong
Department of Medicine, University of Ulsan College of Medicine, Songpa Gu, Seoul, Korea
Circulation 107:517-20. 2003..The aim of this study was to use serial volumetric intravascular ultrasound (IVUS) to evaluate the effect of a paclitaxel coating on in-stent intimal hyperplasia (IH)...
- Growth of nano-scale hydroxyapatite using chemically treated titanium oxide nanotubesSeung Han Oh
Department of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, Bldg EBU 2, RM, La Jolla, CA 92093, USA
Biomaterials 26:4938-43. 2005..Such TiO2 nanotube arrays and associated nanostructures can be useful as a well-adhered bioactive surface layer on Ti implant metals for orthopaedic and dental implants, as well as for photocatalysts and other sensor applications...
- Helical rosette nanotubes: a biomimetic coating for orthopedics?Ai Lin Chun
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907 2022, USA
Biomaterials 26:7304-9. 2005....
- Role of stent design and coatings on restenosis and thrombosisHidehiko Hara
Minnesota Cardiovascular Research Institute, Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, 920 East 28th Street Suite 620, Minneapolis, MN, 55407, USA
Adv Drug Deliv Rev 58:377-86. 2006..This chapter describes stents which have subtle influences of modular design, metal coverage, strut thickness, strut shape, surface smoothness, and coating materials like an alloy composition...
- Covered versus uncovered wallstent for malignant extrahepatic biliary obstruction: a cohort comparative analysisDo Hyun Park
Department of Internal Medicine, Soon Chun Hyang University Cheonan Hospital, Cheonan, Korea
Clin Gastroenterol Hepatol 4:790-6. 2006....
- Enhanced osteoblast adhesion on hydrothermally treated hydroxyapatite/titania/poly(lactide-co-glycolide) sol-gel titanium coatingsMichiko Sato
School of Materials Engineering, Purdue University, West Lafayette, IN 47907, USA
Biomaterials 26:1349-57. 2005....
- Increased osteoblast cell density on nanostructured PLGA-coated nanostructured titanium for orthopedic applicationsLester J Smith
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA
Int J Nanomedicine 2:493-9. 2007..This straight forward application of nano-topography on current bone implant materials represents a new direction in the design of enhanced biomaterials for the orthopedic industry...
- Peptide-immobilized nanoporous alumina membranes for enhanced osteoblast adhesionErin E Leary Swan
Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA
Biomaterials 26:1969-76. 2005..Cell secreted matrix was absent on unmodified membranes for the same duration. Vitronectin-adsorbed surfaces did not show significant improvement in adhesion over unmodified membranes...
- Enhanced fibronectin adsorption on carbon nanotube/poly(carbonate) urethane: independent role of surface nano-roughness and associated surface energyDongwoo Khang
Division of Engineering, Brown University, 184 Hope Street, Providence, RI 02912, USA
Biomaterials 28:4756-68. 2007....
- Short term in vivo biocompatibility testing of biodegradable poly(D,L-lactide)--growth factor coating for orthopaedic implantsBritt Wildemann
Center for Musculoskeletal Surgery, Charite, University Medicine, Augustenburger Platz 1, Berlin D 13353, Germany
Biomaterials 26:4035-40. 2005..In conclusion, no indication of a foreign body reaction due to the use of the polylactide or the growth factors was found indicating a good short-term biocompatibility of this bioactive coating...
- Drug-eluting bioresorbable stents for various applicationsMeital Zilberman
Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel
Annu Rev Biomed Eng 8:153-80. 2006..Because a lot of research in this field has been done by us, examples for these functions are described based mainly on developments in our laboratories...
- Hydroxyapatite-coated tapered cementless femoral components in total hip arthroplastyBryan Chambers
Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Arthroplasty 22:71-4. 2007..Although these advantages have not been shown to significantly increase long-term durability, there is sufficient data to support the routine use of HA-coated, tapered cementless femoral stems in THA...
- Early failure of hemispheric hydroxyapatite-coated acetabular cupsShin Yoon Kim
Department of Orthopaedic Surgery, Kyungpook National University, School of Medicine, Daegu, Korea
Clin Orthop Relat Res 446:233-8. 2006..5%, respectively. Total hip arthroplasties using an hydroxyapatite-coated smooth hemispheric acetabular cup showed an unexpected high failure rate in terms of fixation, occurrence of osteolysis, and revision after midterm followup...
- In vivo effects of RGD-coated titanium implants inserted in two bone-gap modelsBrian Elmengaard
Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Aarhus University Hospital, AKH, Norrebrogade 44, bygn 1a, DK 8000 Aarhus C, Denmark
J Biomed Mater Res A 75:249-55. 2005..RGD peptide coatings can potentially be used to enhance tissue integration in these challenging environments...
- Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysisMarco Valgimigli
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
J Am Coll Cardiol 47:507-14. 2006....
- The use of a hydroxyapatite-coated primary stem in revision total hip arthroplastyStephen J Kelly
Department of Orthopaedics and Rehabilitation, McClure Musculoskeletal Research Center, University of Vermont, Burlington, Vermont 05405 0084, USA
J Arthroplasty 21:64-71. 2006..These results are superior to previous reports of primary cementless stems for revision THA. The use of a cementless nonmodular implant provides a viable option in some patients undergoing revision THA...
- Early failure of smooth hydroxyapatite-coated press-fit acetabular cup--7 years of follow-upKin Wing Cheung
Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
J Arthroplasty 20:627-31. 2005..Radiolucent line was not an accurate sign for the detection of mechanical failure...
- Human osteoblast response to pulsed laser deposited calcium phosphate coatingsA Bigi
Department of Chemistry G Ciamician, University of Bologna, via Selmi, 2, Bologna 40126, Italy
Biomaterials 26:2381-9. 2005..Our data demonstrate that both calcium phosphate coatings favour osteoblasts proliferation, activation of their metabolism and differentiation...
- The effect of different titanium and hydroxyapatite-coated dental implant surfaces on phenotypic expression of human bone-derived cellsChristine Knabe
Department of Experimental Dentistry, University Hospital Benjamin Franklin, Free University of Berlin, Assmannshauser Str 4 6, 14197 Berlin, FRG
J Biomed Mater Res A 71:98-107. 2004..Furthermore, Ti-DPS surfaces induced greater osteoblast proliferation and differentiation than Ti-TPS...
- Protein resistance of titanium oxide surfaces modified by biologically inspired mPEG-DOPAJeffrey L Dalsin
Biomedical Engineering Department, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA
Langmuir 21:640-6. 2005....
- An in vitro analysis of a carotid artery stent with a protective porous membraneStefan Muller-Hulsbeck
Department of Radiology, University Hospital, Arnold Heller Strasse 9, 24105 Kiel, Germany
J Vasc Interv Radiol 15:1295-305. 2004..To prove the effectiveness of a new stent concept with integrated protection (MembraX [MX]) by comparing it with five cerebral protection devices designed for carotid angioplasty in an in vitro model...
- Grit-blasted and hydroxyapatite-coated total hip arthroplasty: an 11- to 14-year follow-up studyShumpei Miyakawa
Doctoral Program in Sports Medicine, Graduate School of Comprehensive Human Science, The University of Tsukuba, 1 1 1 Tennodai, 305 8577, Tsukuba, Japan
J Orthop Sci 9:462-7. 2004..The suboptimal result of the hydroxyapatite-coated smooth cup indicates that porous coatings under the hydroxyapatite coating would be beneficial for hydroxyapatite-coated total hip implants, especially for the acetabular components...
- Controlled release of insulin from PLGA nanoparticles embedded within PVA hydrogelsJ Liu
Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, China
J Mater Sci Mater Med 18:2205-10. 2007....
- Hip arthroplasty in patients younger than 30 years: excellent ten to 16-year follow-up results with a HA-coated stemH Wangen
Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Centre, 0027, Oslo, Norway
Int Orthop 32:203-8. 2008..In conclusion, we found mechanical failures at the acetabular side, but excellent results with a fully HA-coated femoral stem, with no revisions after ten to 16 years...
- Self-sterilization using silicone catheters coated with Ag and TiO2 nanocomposite thin filmYanyan Yao
Department of Urology and Molecular Science, Graduate School of Medicine, Yokohama City University, 3 9 Fukuura, Yokohama 236 0004, Japan
J Biomed Mater Res B Appl Biomater 85:453-60. 2008..This type of catheter shows a great promise in lowering the incidence of catheter-related bacterial infections...
- Studies of photokilling of bacteria using titanium dioxide nanoparticlesYang Hwei Tsuang
Department of Orthopedic Surgery, Taipei City Hospital, Taipei, Taiwan
Artif Organs 32:167-74. 2008..In the presence of UV light, the titanium dioxide nanoparticles can be applicable to medical facilities where the potential for infection should be controlled...
- Vancomycin derivative photopolymerized to titanium kills S. epidermidisMcKinley C Lawson
Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA
Clin Orthop Relat Res 461:96-105. 2007..This coating method allows a loading dose several thousand times larger than that achieved with monolayer vancomycin coupling approaches and holds promise for the treatment of orthopaedic infections...
- Biocompatibility of nanoporous alumina membranes for immunoisolationKristen E La Flamme
Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
Biomaterials 28:2638-45. 2007..Further, in vivo work has demonstrated that implantation of these capsules into the peritoneal cavity of rats induces a transient inflammatory response, and that PEG is useful in minimizing the host response to the material...
- Modeling of degradation and drug release from a biodegradable stent coatingSantosh Prabhu
Cardiac Therapies, Abbott Vascular, Santa Clara, California 95054, USA
J Biomed Mater Res A 80:732-41. 2007..In addition, this modeling methodology has broader applications and can be used to develop mathematical models for predicting the degradation and drug release kinetics for other polymeric drug delivery systems...
- N-halamine biocidal coatingsJ Liang
Department of Chemistry, Auburn University, Auburn, AL 36849, USA
J Ind Microbiol Biotechnol 34:157-63. 2007..Synthetic schemes and biocidal efficacy data are presented. The stabilities of the bound chlorine on the surfaces are also addressed. Substrates employed include sand, textiles, and paint. Potential uses for the technology are discussed...
- Locally delivered TGF-beta1 and IGF-1 enhance the fixation of titanium implants: a study in dogsAnders Lamberg
Department of Orthopaedic Surgery, Aarhus University Hospital, Denmark
Acta Orthop 77:799-805. 2006..We examined the effect of locally delivered transforming growth factor-beta1 and insulin-like growth factor-1 in a biodegradable poly (D, L-lactide) coating...
- Hydroxyapatite-coated femoral components: 15-year minimum followupWilliam N Capello
Indiana University School of Medicine, Department of Orthopaedic Surgery, 541 Clinical Drive CL600, Indianapolis, IN 46202, USA
Clin Orthop Relat Res 453:75-80. 2006..6% at 15-year minimum followup. The data demonstrate excellent long-term survivorship of this hydroxyapatite-coated femoral component used in a relatively young patient group...
- Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility studyJordi Rello
Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
Crit Care Med 34:2766-72. 2006..To assess the feasibility and safety of the respiratory infection control (RIC) device, a silver-coated endotracheal tube, and its effect on bacterial burden in the airways...
- Cell fouling resistance of polymer brushes grafted from ti substrates by surface-initiated polymerization: effect of ethylene glycol side chain lengthXiaowu Fan
Department of Biomedical Engineering, Robert R McCormick School of Engineering and Applied Sciences, Northwestern University, Evanston, Illinois 60208, USA
Biomacromolecules 7:2443-8. 2006....
- Porous-coated cups fixed with screws: a 12-year clinical and radiostereometric follow-up study of 50 hipsStephan M Rohrl
Department of Orthopaedic Surgery, Flinders University and Flinders Medical Centre, Adelaide, Australia
Acta Orthop 77:393-401. 2006..We evaluated the clinical and radiographic results of 50 patients followed for 12 years...
- Sirolimus-eluting stent in chronic total occlusion: the SICTO studyChaim Lotan
Hadassah Hebrew University Medical Centre, Jerusalem, Israel
J Interv Cardiol 19:307-12. 2006..The CYPHER sirolimus-eluting stent was safe and effective in the treatment of CTO compared to historical data with bare metal stents...
- Hydroxyapatite coating by sol-gel on Ti-6Al-4V alloy as drug carrierEduardo Peón Avés
Department of Ceramic and Composites, Centro de Biomateriales, Universidad de La Habana, Havana, Cuba
J Mater Sci Mater Med 20:543-7. 2009....
- Atomic force microscopy probing platelet activation behavior on titanium nitride nanocoatings for biomedical applicationsVarvara Karagkiozaki
Department of Physics, Laboratory for Thin Films Nanosystems and Nanometrology, Aristotle University of Thessaloniki, Thessaloniki, Greece
Nanomedicine 5:64-72. 2009..It was found that the TiN(x) films stoichiometry and surface roughness affect the platelet response. The stoichiometric and smoother TiN films promote platelets adhesion and activation...
- Frequency of and risk factors for stent thrombosis after drug-eluting stent implantation during long-term follow-upDuk Woo Park
Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Am J Cardiol 98:352-6. 2006..6%, similar to that for bare metal stents. The predictors of stent thrombosis were premature antiplatelet therapy interruption, primary stenting in acute myocardial infarction, and total stent length...
- Effect of hydroxyapatite coating on risk of revision after primary total hip arthroplasty in younger patients: findings from the Danish Hip Arthroplasty RegistryAksel Paulsen
Department of Orthopaedic Surgery, Odense University Hospital, University of Southern Denmark, Denmark
Acta Orthop 78:622-8. 2007..The effect of hydroxyapatite (HA) on implant survival in the medium and long term is uncertain. We studied the effect of HA coating of uncemented implants on the risk of cup and stem revision in primary total hip arthroplasty (THA)...
- Long-term results of HA coated threaded versus HA coated hemispheric press fit cups: 287 hips followed for 11 to 16 yearsOlav Reikeras
Orthopaedic Department, Rikshospitalet University Clinic, 0027 Oslo, Norway
Arch Orthop Trauma Surg 126:503-8. 2006..In this paper, we report 11 to 16 years follow up results of HA coated threaded versus HA coated hemispherical press fit cups...
- Surface engineering approaches to micropattern surfaces for cell-based assaysDidier Falconnet
BioInterfaceGroup, Laboratory for Surface Science and Technology, Department of Materials, Swiss Federal Institute of Technology ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
Biomaterials 27:3044-63. 2006....
- Influence of silicon concentration on the haemocompatibility of amorphous carbonSoon Eng Ong
School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore
Biomaterials 28:4033-8. 2007..Bonding structure and surface energy were determined to be factors contributing to the improved haemocompatibility...
- Plasma-mediated grafting of poly(ethylene glycol) on polyamide and polyester surfaces and evaluation of antifouling ability of modified substratesBaiyan Dong
Center for Plasma Aided Manufacturing, 1410 Engineering Drive, University of Wisconsin Madison, Madison, WI 53706, USA
Langmuir 23:7306-13. 2007..This plasma functionalization method provided an efficient way to graft PEG onto PA and PET surfaces. Because of the high reactivity of Si-Cl species, this method could potentially be applied to other polymeric materials...
- Risk of thrombosis with the use of sirolimus-eluting stents for percutaneous coronary intervention (from registry and clinical trial data)Anthony A Bavry
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Cardiol 95:1469-72. 2005..Compared with bare metal stents, sirolimus-eluting stents did not appear to increase the risk for thrombosis up to 13.5 months after coronary intervention (risk ratio 0.49, 95% confidence interval 0.22 to 1.12, p = 0.09)...
- High wear rates and extensive osteolysis in 3 types of uncemented total hip arthroplasty: a review of the PCA, the Harris Galante and the Profile/Tri-Lock Plus arthroplasties with a minimum of 12 years median follow-up in 96 hipsGeir Hallan
Department of Orthopaedic Surgery, Haukeland University Hospital Bergen Norway
Acta Orthop 77:575-84. 2006..High wear rates and femoral and acetabular osteolysis have been-and still are-the main problems in uncemented total hip replacement. We reviewed 96 consecutive cementless total hip replacements of 4 different designs...
- Polymerizable vancomycin derivatives for bactericidal biomaterial surface modification: structure-function evaluationMcKinley C Lawson
Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA
Biomacromolecules 10:2221-34. 2009..In particular, the vancomycin-PEG-acrylate derivatives demonstrated a 7-8 log reduction in bacterial colony forming units (CFU) with respect to nonfunctionalized control surfaces...
- Polyelectrolyte multilayer films with pegylated polypeptides as a new type of anti-microbial protection for biomaterialsF Boulmedais
Institut Charles Sadron, UPR 22 CNRS, 6 rue Boussingault, 67083 Strasbourg Cedex, France
Biomaterials 25:2003-11. 2004..This kind of anti-adhesive films represents a new and very simple method to coat any type of biomaterials for protection against bacterial adhesion and therefore limiting its pathological consequences...
- Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesionsAntonio Colombo
Ospedale San Raffaele, Milano, Italy
Circulation 108:788-94. 2003..Early clinical studies demonstrated the feasibility of local paclitaxel delivery in reducing restenosis after treatment of de novo coronary lesions in small patient populations...
- Survival and polyethylene wear of porous-coated acetabular components in patients less than fifty years old: results at nine to fourteen yearsJames D Crowther
Department of Orthpaedics, University of North Carolina, Chapel Hill 27599, USA
J Bone Joint Surg Am 84:729-35. 2002..In this report, we present the results associated with the use of an uncemented acetabular component in young patients who were evaluated at a minimum of nine years postoperatively...
- The impact of heparin-coated cardiopulmonary bypass circuits on pulmonary function and the release of inflammatory mediatorsR de Vroege
Departments of Extracorporeal Circulation, Room 6A 149, Vrije Universiteit Medisch Centrum, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Anesth Analg 98:1586-94, table of contents. 2004..The correlation with sPLA(2), leukocyte activation, and postoperative leukocyte count suggests reduced activation of pulmonary capillary endothelial cells...
- Reduction in neointimal formation with a stent coated with multiple layers of releasable heparin in porcine coronary arteriesYasuharu Matsumoto
Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
J Cardiovasc Pharmacol 39:513-22. 2002..8 +/- 1.0) than at the control stent site (19.1 +/- 1.7) (p < 0.01). These results suggest that the stent coated with releasable heparin is beneficial in reducing neointimal formation and subsequent in-stent restenosis...
- Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogsMerle E Olson
Department of Microbiology and Infectious Diseases, Animal Resources Center, The University of Calgary, Alberta, Canada
Chest 121:863-70. 2002..To evaluate the influence of silver-coated endotracheal tubes on the lung bacterial burden of mechanically ventilated dogs...
- Silver coated materials for external fixation devices: in vitro biocompatibility and genotoxicityM Bosetti
Department of Medical Sciences, Human Anatomy, University of Eastern Piemonte, Novara, Italy
Biomaterials 23:887-92. 2002..Based on these and the previous bacterial studies it seems like the toxicity towards bacteria was quite a bit greater than that towards the human cells...
- Cementless Spotorno tapered titanium stems: excellent 10-15-year survival in 141 young patientsPeter R Aldinger
Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstrasse 200a, DE 69118 Heidelberg, Germany
Acta Orthop Scand 74:253-8. 2003..However, the high rate of cup loosening and the low Harris hip scores are a concern in this subgroup of young patients...
- Effects of solution pH and electrical parameters on hydroxyapatite coatings deposited by a plasma-assisted electrophoresis techniqueX Nie
Research Centre in Surface Engineering, University of Hull, Hull, HU6 7RX, UK
J Biomed Mater Res 57:612-8. 2001..Such a nanophase TiO2 layer (if used as a coating alone) may also provide a further improvement in osteoinductive properties, compared to a conventional TiO2 coating on the Ti alloy substrate...
- Efficacy of a new coating material, PMEA, for cardiopulmonary bypass circuits in a porcine modelH Suhara
Department of Surgery, Osaka University Graduate School of Medicine, Japan
Ann Thorac Surg 71:1603-8. 2001..Thus, PMEA coating may be a suitable means for improving the biocompatibility of CPB circuits...
- Hydroxyapatite-coated acetabular components. Histological and histomorphometric analysis of six cups retrieved at autopsy between three and seven years after successful implantationA Tonino
Department of Orthopaedics, De Wever Hospital, Heerlen, The Netherlands
J Bone Joint Surg Am 83:817-25. 2001....
- Malignant biliary obstruction: treatment with ePTFE-FEP- covered endoprostheses initial technical and clinical experiences in a multicenter trialMaria Schoder
Department of Angiography and Interventional Radiology, University of Vienna Medical School, Waehringerguertel 18 20, A 1090 Vienna, Austria
Radiology 225:35-42. 2002..To determine and present the initial technical and clinical results of using an expanded polytetrafluoroethylene-fluorinated ethylene propylene (ePTFE-FEP)-covered biliary endoprosthesis to treat malignant biliary obstruction...
- The odyssey of porous-coated fixationCharles A Engh
Anderson Orthopedic Research Institute, Alexandria, Virginia 22307, USA
J Arthroplasty 17:102-7. 2002..Because of the relatively easy, reproducible surgical technique associated with extensively porous-coated stems and the perception of marginally better outcome, we prefer to use extensively porous-coated stems for all primary THAs...
- Influence of surface modifications to titanium on antibacterial activity in vitroM Yoshinari
Department of Dental Materials Science and Oral Health Science Center, Tokyo Dental College, Chiba, Japan
Biomaterials 22:2043-8. 2001..These findings indicate that surface modification by means of a dry process is useful in providing antibacterial activity of oral bacteria to titanium implants exposed to the oral cavity...
- Biocompatilibity-related surface characteristics of oxidized NiTiAnatoli Danilov
Department of Medical Technology, University of Oulu, PO Box 5000, Oulu, Finland
J Biomed Mater Res A 82:810-9. 2007..The comparative oxidation of pure titanium and NiTi showed that the effect of Ni on the EWF value of NiTi surface oxide is negligible...
- Degradation characteristics of hydroxyapatite coatings on orthopaedic TiAlV in simulated physiological media investigated by electrochemical impedance spectroscopyRicardo M Souto
Department of Physical Chemistry, University of La Laguna, Campus de Anchieta, E 38071 Tenerife, Canary Islands, La Laguna, Spain
Biomaterials 24:4213-21. 2003..The blocking effect due to salt precipitation inside the pores produces an enhancement of the resistance values, thus effectively diminishing the metal ion release in the system...
- Processing-microstructure-property relations in HVOF sprayed calcium phosphate based bioceramic coatingsK A Khor
School of Mechanical and Production Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore
Biomaterials 24:2233-43. 2003..The relationship among the processing, microstructure, and mechanical properties of the HVOF sprayed bioceramic coatings was summarily examined...
- Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorptionO Reigstad
Orthopaedic Department, Rikshospitalet National Hospital, 0027 Oslo, Norway
J Biomed Mater Res B Appl Biomater 83:9-15. 2007..This unloaded short-term study has shown promising results for the easily applicable and resorbable coat (Bonit) compared to uncoated titanium-alloy implants...
- Biological responses in osteoblast-like cell line according to thin layer hydroxyapatite coatings on anodized titaniumS H Sohn
Department of Biochemistry, College of Medcine, Korea University, Seongbuk gu, Seoul, Korea
J Oral Rehabil 33:898-911. 2006..The attachment and expression of key osteogenic regulatory genes were enhanced by the surface morphology of the dental materials used...
- Properties and immersion behavior of magnetron-sputtered multi-layered hydroxyapatite/titanium composite coatingsShinn Jyh Ding
Institute of Dental Materials, Chung Shan Medical University, Taichung, 402, Taiwan ROC
Biomaterials 24:4233-8. 2003..The adhesion strength higher than 60MPa did not change much even after 14 weeks of immersion. The multi-layered composite coatings had the advantages of high and non-declining adhesion strength and high resistance to SBF attack...
- Quantification of fibrinogen adsorption onto 316L stainless steelRobert T T Gettens
Department of Biomedical and Chemical Engineering, Syracuse University, Link Hall 121, Syracuse, New York 13244, USA
J Biomed Mater Res A 81:465-73. 2007..Complete area coverage was never obtained. That is, after adsorption for over 5 time constants (5tau), voids in the structure were always observed...
- Biocompatibility of electrophoretical deposition of nanostructured hydroxyapatite coating on roughen titanium surface: in vitro evaluation using mesenchymal stem cellsF Chen
State Key Laboratory for Physical Chemistry of Solid Surfaces, Department of Chemistry, Xiamen University, Xiamen 361005, China
J Biomed Mater Res B Appl Biomater 82:183-91. 2007..Proliferation of the MSCs on the nano-HAp coating was higher than its micron counterpart in XTT assay. These properties show potential for the orthopaedic and dental applications...
- Evaluation of corrosion on plasma sprayed and anodized titanium implants, both with and without bone cementL Reclaru
Groupe PX, PX Tech, Bldv des Eplature 46, La Chaux de Fonds 2304, Switzerland
Biomaterials 24:3027-38. 2003..We cannot deduce from our results, however, whether the polymer itself possesses corrosive properties. Long-term experiments will be necessary to study the degradation behavior of the polymer cement...
- The effects of conductivity and electrochemical doping on the reduction of methemoglobin immobilized in nanoparticulate TiO2 filmsElizabeth V Milsom
Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK
Bioelectrochemistry 70:221-7. 2007..TiO(2) can be temporarily switched from a non-conducting (irreversible electron transfer) into a conducting (reversible electron transfer) state...
- Preparation and osteocompatibility of hydroxyapatite coated on titanium from the reaction of sputtered CaO and vaporized P2O5K Ozeki
Applied Systems Engineering, Graduate School of Science and Engineering, Tokyo Denki University, Ishizaka, Hatoyama, Hiki, Saitama, 350 0394, Japan
Biomed Mater Eng 13:83-90. 2003....
- In vitro corrosion behavior of bioceramic, metallic, and bioceramic-metallic coated stainless steel dental implantsM H Fathi
Department of Materials Engineering, Isfahan University of Technology, 84154, Isfahan, Iran
Dent Mater 19:188-98. 2003..The aim of this work was to evaluate the corrosion behavior and thus the biocompatibility of the uncoated and coated stainless steels and compare the effect of type of coatings on corrosion behavior...
- Effects of ion beam-assisted deposition of hydroxyapatite on the osseointegration of endosseous implants in rabbit tibiaeY C Jung
Department of Dentistry, St Vincent's Hospital, School of Medicine, The Catholic University of Korea, Seoul
Int J Oral Maxillofac Implants 16:809-18. 2001..05)...
- Deposition of nano-hydroxyapatite particles utilising direct and transitional electrohydrodynamic processesZ Ahmad
Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK
J Mater Sci Mater Med 19:3093-104. 2008..The results indicate the robustness of the electrohydrodynamic route in the nano-materials processing arena, with emphasis on biomedical materials...
- Hydroxyapatite coatings produced on commercially pure titanium by micro-arc oxidationYong Huang
College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, People s Republic of China
Biomed Mater 2:196-201. 2007..The favorable osteoblast cell affinity gives HA film good biocompatibility. HA coatings are expected to have significant uses for medical applications such as dental implants and artificial bone joints...
- Hydroxyapatite coating on Ti6Al4V alloy by a sol-gel methodDiangang Wang
School of Materials Science and Engineering, Shandong University, Jinan, 250061, P R China
J Mater Sci Mater Med 19:2281-6. 2008....
- Electrohydrodynamic coating of metal with nano-sized hydroxyapatiteXiang Li
Department of Mechanical Engineering, University College London, London, UK
Biomed Mater Eng 17:335-46. 2007..Therefore, we have uncovered a new procedure by which nano-biomaterials can be deposited on real orthopedic substrates to prepare bioactive thin coatings in a simple and easy manner...
- Development of nano-hydroxyapatite coating by electrohydrodynamic atomization sprayingXiang Li
Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK
J Mater Sci Mater Med 19:1545-51. 2008..3 kV and 5.2 kV, a uniform nHA coating was obtained. This is a crucial step forward in obtaining advanced nano-hydroxyapatite coatings of high quality for biomedical applications by using EHDA spraying...
- [Bioactive films for biomaterial coating and intended for tissue engineering: new original methods?]P Schaaf
Institut Charles Sadron, ULP CNRS UPR22, 6, rue Boussingault, 67083 Strasbourg, France
Pathol Biol (Paris) 50:189-93. 2002..Combined with a high affinity for calcium or phosphate complexing properties such functionalized architectures could constitute an original way to favour osseointegration...
- Thin films of SiO2 and hydroxyapatite on titanium deposited by spray pyrolysisV Jokanovic
Institute of Nuclear Sciences Vinca Laboratory for Radiation Chemistry and Physics, P O Box 522, Belgrade 11001, Republic of Serbia
J Mater Sci Mater Med 19:1871-9. 2008..A hydroxyapatite film was prepared on the so-obtained SiO2 thin film by spray pyrolysis deposition and its morphology and phase composition were investigated...
- Preparation and characteristics of nano-grained calcium phosphate coatings on titanium from ultrasonated bath at acidic pHR Narayanan
Department of Dental Biomaterials, College of Dentistry, Institute for Biomaterials Research and Development, KNU School of Dentistry BK21, Kyungpook National University, Daegu, Korea
J Biomed Mater Res B Appl Biomater 85:231-9. 2008..Heat-treatment of the coatings for 2 h at 500 degrees C completely eliminated the dicalcium phosphate phase and resulted in mono hydroxyapatite phase containing grains in the size range of 20-30 nm...
- Preparation of an electrodeposited hydroxyapatite coating on titanium substrate suitable for in-vivo applicationsSuping Huang
State Key Laboratory for Powder Metallurgy, Central South University, Changsha, Hunan 410083, PR China
J Mater Sci Mater Med 19:437-42. 2008..05), which demonstrated that HA-coated Ti has a good biocompatibility...
- Nucleation and growth of apatite on chemically treated titanium alloy: an electrochemical impedance spectroscopy studyC X Wang
School of Mechanical and Production Engineering, Nanyang Technological University, Nanyang Avenue, Singapore 639798, Singapore
Biomaterials 24:3069-77. 2003..It was found that EIS is a useful method for investigating the nucleation and growth of bone-like apatite on Ti6Al4V pretreated with NaOH solution...
- Helical Rosette Nanotubes for Treating Osteoporotic BoneThomas Webster; Fiscal Year: 2008..abstract_text> ..
- PACING, SENSING AND DEFIBRILLATION ELECTRODE COATINGSStuart Cogan; Fiscal Year: 2006..The in vivo studies will be done with collaborators at the University of Alabama. [unreadable] [unreadable]..
- Electrodeposited Noble Metal Oxide Nerve ElectrodesStuart Cogan; Fiscal Year: 2006..abstract_text> ..
- Conductive Polymer Recording and Stimulation ElectrodesStuart Cogan; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- MODEL FOR ELECTRODE TESTING AND REDUCED ANIMAL USEStuart Cogan; Fiscal Year: 2003..The validity of the inanimate and living models will be evaluated by comparison of electrode function in the in vitro models with that observed under identical test protocols in the chronic cat cortex. ..
- Functionalized Coatings for Enhanced Neural InterfacesStuart Cogan; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Wearable Organic Electric Film RFID Sensors for Monitoring of Airborne ToxicantsRadislav A Potyrailo; Fiscal Year: 2010..This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species. ..
- Biomimetic Scaffolds for Abdominal Wall RepairAnshu Mathur; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Targeted Delivery of Anthrax InhibitorsMarina Backer; Fiscal Year: 2007..In Phase II we will develop LFn-liposomes with combination of LF and EF inhibitors, validate these liposomes in animal models of anthrax infection, and pre-clinical steps required for IND filing. [unreadable] [unreadable] [unreadable]..
- Ultrasound Monitoring of Rat Metastatic Uveal MelanomaRODNEY BRAUN; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- INTERFACE MECHANICS, MATERIALS AND TISSUE RESPONSEJoan Sanders; Fiscal Year: 2007..The development of methods to predict and overcome the detrimental effects of residual limb shape change and ultimately prevent soft-tissue breakdown will help to prevent secondary disability and morbidity in the amputee population. ..
- Detection of Topoisomerase II Mediated DNA Damage in StrokeVLADIMIR DIDENKO; Fiscal Year: 2007..It will also have a broad applicability in all fields of biomedicine where detection of early apoptosis is important. [unreadable] [unreadable] [unreadable]..
- Glial Biology Gordon Research ConferenceVladimir Parpura; Fiscal Year: 2007..This Glial Biology Conference provides an international forum for emerging, innovative research related to glia functions and cell-cell interactions in health and disease. ..
- Development of Magnetic Sensors for MRI Cancer ImagingJ Perez; Fiscal Year: 2007..The proposed research will be conducted in a multidisciplinary environment and the integrated training and research program will enable the candidate to establish himself as an independent cancer researcher. [unreadable] [unreadable]..
- Multiaxial Single-Cell Biomechanics for MechanotransductionSEAN KOHLES; Fiscal Year: 2007..contribute to the understanding of pathologic cell states and therapeutic approaches for load-bearing tissues, and guide the design of engineered biomaterials which control cellular function [unreadable] [unreadable] [unreadable]..
- Semi-artificial nanomachines for detection of DNA damage and apoptosisVLADIMIR DIDENKO; Fiscal Year: 2008..abstract_text> ..
- Cellular MRI in Glioma and Radiation NecrosisAli Syed Arbab; Fiscal Year: 2010..Early detection of recurrent or metastatic glioma as well as early differentiation of glioma from radiation necrosis will help clinician to tackle the devastating neurological disease. ..
- Real-time MRI-guided RF Ablation of Cardiac TachyArrhythmiasOrhan Unal; Fiscal Year: 2010..Successful completion of this project is expected to improve safety, simplicity, and efficacy catheter ablation procedure to treat AF. ..
- Semiconductor Nanosensors for Label-Free Detection of Antigens and Cellular ImmunMark Reed; Fiscal Year: 2010..These nanosensors can replace current technology with a powerful solid-state device useful for rapid diagnosis in clinical settings. ..
- BIOSENSOR ARRAYS BASED ON SINGLE WALL CARBON NANOTUBESJames F Rusling; Fiscal Year: 2010..In addition to achieving our specific aims, this project should provide fundamental guidance for fabrication of sensitive microarray devices for a wide variety of biomedical applications. ..
- Orchestrating Bone Regeneration on Multiple ScalesPeter X Ma; Fiscal Year: 2010..SA 3. Confirm that the multi-scaled and factor-releasing scaffolds (selected from Aims 1&2) afford a superior environment for vascularized bone regeneration in a rat critical defect model. ..
- Towards the development of a "living" cochlear implantXuejun Wen; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- IMPROVING THE DETECTION LIMIT OF POTENTIOMETRIC SENSORSJoseph Wang; Fiscal Year: 2008..The perturbance of such fluxes by surface binding events will be used to explore novel approaches to biosensing at liquid-polymer interfaces. ..
- Differentiation of Glioma from Radiation Injury Using Cellular MRISyed Ali; Fiscal Year: 2008..This magnetic labeling technique will also help investigators to track the injected CTL in the body as well as in the targeted areas by magnetic resonance imaging (MRI). [unreadable] [unreadable] [unreadable]..
- Nano Fibers for ADME/ToxicologyPeter Ma; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Targeting GRP78/BIP As An Adjunct Therapy For EGFR-positive Breast CancerMarina Backer; Fiscal Year: 2008..We expect that this data establish feasibility of clinical development for EGF-SLiP. [unreadable] [unreadable] [unreadable]..
- Engineered neuronal networks for drug screeningPeter Molnar; Fiscal Year: 2008..abstract_text> ..
- Pathogenesis of Experimental Necrotizing EnterocolitisHenri Ford; Fiscal Year: 2006..III) To determine the effects of scavengers of NO or inhibitors of NO production on the development of experimental rodent NEC. ..
- Skin Adaptation to Mechanical StressJoan Sanders; Fiscal Year: 2006..By understanding the process of skin adaptation (natural skin strengthening) at both a cellular and molecular level, therapies to encourage skin adaptation before breakdown occurs can be intelligently pursued. ..
- Composition/Functional Elasticity of Engineered TissuesSEAN KOHLES; Fiscal Year: 2003..The results will be used to predict the time-dependent performance of cell-polymer constructs, and to gain insight into the mechanisms of scaffold degradation and ECM synthesis...
- Physical Regulation of Skeletal Repair WorkshopRoy Aaron; Fiscal Year: 2003..Finally, how repairing skeletal tissues organize physical information to augment the repair process, and what translational opportunities exist, will be considered. ..
- STRUCTURES OF ACETYLCHOLINE RECEPTORSArthur Karlin; Fiscal Year: 2003..The Cys will be substituted for residues known to contribute to the binding of ACh. ..
- INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSEJoan Sanders; Fiscal Year: 2003....
- Biomimetic Nano ScaffoldsPeter Ma; Fiscal Year: 2004..This knowledge will enable us to develop a predictable biomimetic scaffold for in vivo application and will be the basis for our planned R01 investigation. ..
- A Novel Technique of Imposing Femtonewton ForcesJin Yu Shao; Fiscal Year: 2004..Therefore, the EMAT should have great potential to make an impact in the field of single molecule and single bond biophysics. ..
- Osteoblast response to strain at implant-tissue interfacJoel Bumgardner; Fiscal Year: 2003..Furthermore, it may also be useful in identifying loading parameters that promote osteointegration. ..
- EXERCISE AND CARDIOVASCULAR DISEASEWilliam Weintraub; Fiscal Year: 2003..Not only existing markers of oxidative stress, but also novel surrogate markers, such as, plasma soluble VCAM-l, myeloperoxidase, and autoantbodies to oxidatively modified proteins will be measured. ..
- Coating Reduces Encrustation on Urethral StentShih Horng Su; Fiscal Year: 2004..Ureteral stents equipped with the anti-encrustation coating will be compared to many similar products on the market in the aspect of encrustation severity. The data will guide future optimization. ..
- Analysis & Control of Non-Synaptic Epileptiform ActivityDominique Durand; Fiscal Year: 2004..The results of our studies should provide valuable insight into mechanisms underlying epileptogenesis as well as new tools for the control and suppression of epileptic seizures. ..
- Effect of defined surfaces on cardiac myocyte physiologyPeter Molnar; Fiscal Year: 2004..Results obtained in this study would have a high impact on the progress of the emerging new cardiac tissue engineering methods. ..
- SELECTINS ROLE IN VASCULAR INJURY IN GENE-TARGETEDIan Sarembock; Fiscal Year: 2004..In addition, these studies will open new avenues to potential therapeutic strategies to limit neointimal growth after vascular injury. ..
- INTERFACE MECHANICS, MATERIALS, AND TISSUE RESPONSEJoan Sanders; Fiscal Year: 2002....
- ROLES OF NITRIC OXIDE AND OXYGEN IN OCULAR MELANOMARODNEY BRAUN; Fiscal Year: 2002....
- Optimization of Cure Efficiency in Polymeric BiomaterialLawrence Musanje; Fiscal Year: 2006..A light emitting diode (LED) whose emission adequately overlaps the absorption spectrum of photosensitizer will be chosen. ..
- Assessment of Tissue Response to StressJoan Sanders; Fiscal Year: 2006..this technology could be applied to other areas of rehabilitation, for example, shoe design for patients with insensate feet, cushion design for wheelchair users, and mattress design for bedridden patients [unreadable] [unreadable]..
- Novel Biomaterials Guiding Supercrestal Bone GrowthMei Wei; Fiscal Year: 2008..This will also improve the reliability of the surgery and reduce the risk, pain and disruption associated with bone augmentation [unreadable] [unreadable] [unreadable]..
- Calcium-dependent glutamate release from astrocytesVladimir Parpura; Fiscal Year: 2008..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions [unreadable] [unreadable]..
- NEW BIOMATERIALS TO MINIMIZE SCAR TISSUE FORMATIONJoan Sanders; Fiscal Year: 2002..e. soft-tissue complications that require surgical repair through use of a biomaterial. The new materials will prevent scar tissue formation and reduce the occurrence of secondary complications. ..
- Estrogen: Chrodroprotective or Destructive?Sally Frenkel; Fiscal Year: 2002..The inconclusive and contradictory data from human and animal studies render the proposed studies highly significant. ..
- FUNDAMENTALS OF SURGICAL RESEARCH COURSEHenri Ford; Fiscal Year: 2008..Therefore, promoting, educating and training the young surgical investigator in the responsible conduct of research is an essential component of the Fundamentals of Surgical Research Course. ..
- Quantifying Axon Growth in Complex EnvironmentsDiane Hoffman Kim; Fiscal Year: 2010..The proposed research seeks to solve this problem by quantifying how guidance cues, both individually and in combination, promote axon growth in an inhibitory environment such as a nerve injury site. ..
- Biomechanics on Neutrophil Rolling on the EndotheliumJin Yu Shao; Fiscal Year: 2006..The microvillus mechanics will be studied with the optical tweezers, combined with the micropipette manipulation system. ..
- A Novel Technique of Imposing Femtonewton ForcesJin Yu Shao; Fiscal Year: 2007..Therefore, the EMAT should have great potential to make an impact in the field of single molecule and single bond biophysics. [unreadable] [unreadable]..
- Development of a Multi-phased Scaffold for Soft Tissue to Bone IntegrationHelen Lu; Fiscal Year: 2006..abstract_text> ..
- Antiatherogenic Properties of tert-ButylhydroquinoneWilliam Stone; Fiscal Year: 2004..Commercial development should be accelerated since NIH has already conducted extensive toxicological studies with TBHQ. ..
- Extracellular Mechanisms For Thoracic Aortic AneurysmsJohn Ikonomidis; Fiscal Year: 2008..abstract_text> ..
- ACTIVATION OF TONGUE MUSCLES IN OBSTRUCTIVE SLEEP APNEADominique Durand; Fiscal Year: 2004..It is anticipated that the experimental delineation and validation of these methods will lead to a design of a neuroprosthetic device for the treatment of OSA. ..
- Free radicals detection in aging brain by fullerenesVLADIMIR DIDENKO; Fiscal Year: 2003..At a later stage free radicals will be monitored using magnetic resonance tracer and MRI detection. ..
- Mesoporus Diamondlike Carbon Medical Device MembraneRoger Narayan; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- MULTIPHOTON BIOMEDICAL NANOFABRICATIONPaul Campagnola; Fiscal Year: 2001..3) To fabricate dimensionally complex channels and structures for applications to microfluidics. 4) To fabricate composites and biomaterials for tissue engineering. ..
- Tissue protein imaging via second harmonic generatonPaul Campagnola; Fiscal Year: 2006..iii) Determine ideal optical parameters for SHG imaging of tissues in vivo. ..
- MULTIPHOTON BIOMEDICAL NANOFABRICATIONPaul Campagnola; Fiscal Year: 2003..3) To fabricate dimensionally complex channels and structures for applications to microfluidics. 4) To fabricate composites and biomaterials for tissue engineering. ..