micronutrients

Summary

Summary: Essential dietary elements or organic compounds that are required in only small quantities for normal physiologic processes to occur.

Top Publications

  1. ncbi Micronutrients in pregnancy
    R E Black
    Department of International Health, Johns Hopkins School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Br J Nutr 85:S193-7. 2001
  2. ncbi What works? Interventions for maternal and child undernutrition and survival
    Zulfiqar A Bhutta
    Aga Khan University, Karachi, Pakistan
    Lancet 371:417-40. 2008
  3. ncbi Mechanisms of nutrient modulation of the immune response
    Susanna Cunningham-Rundles
    Host Defenses Program, Department of Pediatrics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY, USA
    J Allergy Clin Immunol 115:1119-28; quiz 1129. 2005
  4. ncbi Effects of prenatal food and micronutrient supplementation on infant development: a randomized trial from the Maternal and Infant Nutrition Interventions, Matlab (MINIMat) study
    Fahmida Tofail
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Am J Clin Nutr 87:704-11. 2008
  5. ncbi Effect of multiple micronutrient supplementation on pregnancy and infant outcomes: a systematic review
    Usha Ramakrishnan
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Paediatr Perinat Epidemiol 26:153-67. 2012
  6. pmc Effects of prenatal food and micronutrient supplementation on child growth from birth to 54 months of age: a randomized trial in Bangladesh
    Ashraful Islam Khan
    International Maternal and Child Health, Department of Women s and Children s Health, Uppsala University, Sweden
    Nutr J 10:134. 2011
  7. ncbi Impact of prenatal multiple micronutrients on survival and growth during infancy: a randomized controlled trial
    Dominique Roberfroid
    Child Health and Nutrition Unit, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium
    Am J Clin Nutr 95:916-24. 2012
  8. pmc Multiple micronutrient supplementation during pregnancy in low-income countries: a meta-analysis of effects on birth size and length of gestation
    Caroline H D Fall
    MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK
    Food Nutr Bull 30:S533-46. 2009
  9. ncbi Effects of a dairy product fortified with multiple micronutrients and omega-3 fatty acids on birth weight and gestation duration in pregnant Chilean women
    Francisco Mardones
    1Department of Public Health, School of Medicine, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Marcoleta 434, Santiago, Chile
    Public Health Nutr 11:30-40. 2008
  10. ncbi Effects of micronutrients on DNA repair
    Andrew R Collins
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, PB 1046, 0316, Oslo, Norway
    Eur J Nutr 51:261-79. 2012

Detail Information

Publications318 found, 100 shown here

  1. ncbi Micronutrients in pregnancy
    R E Black
    Department of International Health, Johns Hopkins School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Br J Nutr 85:S193-7. 2001
    Vitamins and minerals, referred to collectively as micronutrients, have important influences on the health of pregnant women and the growing fetus...
  2. ncbi What works? Interventions for maternal and child undernutrition and survival
    Zulfiqar A Bhutta
    Aga Khan University, Karachi, Pakistan
    Lancet 371:417-40. 2008
    ..93-21.07) and micronutrients (which reduced the risk of low birthweight at term by 16% (relative risk 0.84, 0.74-0.95)...
  3. ncbi Mechanisms of nutrient modulation of the immune response
    Susanna Cunningham-Rundles
    Host Defenses Program, Department of Pediatrics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY, USA
    J Allergy Clin Immunol 115:1119-28; quiz 1129. 2005
    Lack of adequate macronutrients or selected micronutrients, especially zinc, selenium, iron, and the antioxidant vitamins, can lead to clinically significant immune deficiency and infections in children...
  4. ncbi Effects of prenatal food and micronutrient supplementation on infant development: a randomized trial from the Maternal and Infant Nutrition Interventions, Matlab (MINIMat) study
    Fahmida Tofail
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Am J Clin Nutr 87:704-11. 2008
    ..Few data exist for the effects of multiple micronutrient (MM) or food supplementation to undernourished pregnant women on their offsprings' development...
  5. ncbi Effect of multiple micronutrient supplementation on pregnancy and infant outcomes: a systematic review
    Usha Ramakrishnan
    Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Paediatr Perinat Epidemiol 26:153-67. 2012
    Supplementation with multiple micronutrients (MM) during pregnancy may result in improved pregnancy and infant outcomes...
  6. pmc Effects of prenatal food and micronutrient supplementation on child growth from birth to 54 months of age: a randomized trial in Bangladesh
    Ashraful Islam Khan
    International Maternal and Child Health, Department of Women s and Children s Health, Uppsala University, Sweden
    Nutr J 10:134. 2011
    ..The hypothesis was that prenatal MMS and early invitation to food supplementation would increase physical growth in the offspring during 0-54 months and a combination of these interventions would further improve these outcomes...
  7. ncbi Impact of prenatal multiple micronutrients on survival and growth during infancy: a randomized controlled trial
    Dominique Roberfroid
    Child Health and Nutrition Unit, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium
    Am J Clin Nutr 95:916-24. 2012
    Although prenatal multiple micronutrients can improve fetal growth, their benefit on postnatal health remains uncertain.
  8. pmc Multiple micronutrient supplementation during pregnancy in low-income countries: a meta-analysis of effects on birth size and length of gestation
    Caroline H D Fall
    MRC Epidemiology Resource Centre, University of Southampton, Southampton, UK
    Food Nutr Bull 30:S533-46. 2009
    ..Multiple micronutrient deficiencies are common among women in low-income countries and may adversely affect pregnancy outcomes...
  9. ncbi Effects of a dairy product fortified with multiple micronutrients and omega-3 fatty acids on birth weight and gestation duration in pregnant Chilean women
    Francisco Mardones
    1Department of Public Health, School of Medicine, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Marcoleta 434, Santiago, Chile
    Public Health Nutr 11:30-40. 2008
    To test the hypothesis that maternal food fortification with omega-3 fatty acids and multiple micronutrients increases birth weight and gestation duration, as primary outcomes.
  10. ncbi Effects of micronutrients on DNA repair
    Andrew R Collins
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, PB 1046, 0316, Oslo, Norway
    Eur J Nutr 51:261-79. 2012
    ..Interest in the influence of micronutrients on DNA repair activity is prompted by the possibility that the protective effects of fruits and vegetables ..
  11. pmc Micronutrient deficits are still public health issues among women and young children in Vietnam
    Arnaud Laillou
    Global Alliance for Improved Nutrition, Geneva, Switzerland
    PLoS ONE 7:e34906. 2012
    ..As no national data exist on the prevalence of micronutrient deficiencies, a survey was conducted in 2010 to assess the micronutrient status of randomly selected 1526 women of reproductive age and 586 children aged 6-75 mo...
  12. ncbi Multiple micronutrients in pregnancy and lactation: an overview
    Lindsay H Allen
    US Department of Agriculture, ARS Western Human Nutrition Research Center, and Department of Nutrition, University of California, Davis, CA, USA
    Am J Clin Nutr 81:1206S-1212S. 2005
    This overview of multiple micronutrients during pregnancy and lactation emphasizes 2 relatively neglected issues...
  13. pmc Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: a randomised trial
    Jacobien Veenemans
    Wageningen University, Cell Biology and Immunology Group, Wageningen, The Netherlands
    PLoS Med 8:e1001125. 2011
    ..Protection may depend on other nutrients. We measured the effect of supplementation with zinc and other nutrients on malaria rates...
  14. ncbi Impact of micronutrient deficiencies on obesity
    Olga P Garcia
    School of Natural Sciences, Universidad Autonoma de Queretaro, Juriquilla, Mexico
    Nutr Rev 67:559-72. 2009
    ..Further studies are needed to clarify the roles of the different micronutrient deficiencies with respect to obesity and its comorbid conditions...
  15. ncbi Effects of maternal multiple micronutrient supplementation on fetal growth: a double-blind randomized controlled trial in rural Burkina Faso
    Dominique Roberfroid
    Child Health and Nutrition Unit, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium
    Am J Clin Nutr 88:1330-40. 2008
    ..Intrauterine growth retardation is a major predictor of child health in developing countries...
  16. pmc Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial
    Lingxia Zeng
    Department of Public Health, Xi an Jiaotong University College of Medicine, PO Box 46, Xi an, Shaanxi 710061, China
    BMJ 337:a2001. 2008
    To examine the impact of antenatal supplementation with multiple micronutrients or iron and folic acid compared with folic acid alone on birth weight, duration of gestation, and maternal haemoglobin concentration in the third trimester.
  17. ncbi Effects of antenatal multiple micronutrient supplementation on birthweight and gestational duration in Nepal: double-blind, randomised controlled trial
    David Osrin
    International Perinatal Care Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Lancet 365:955-62. 2005
    ..We tested the hypotheses that antenatal multiple micronutrient supplementation would increase infant birthweight and gestational duration...
  18. ncbi Prenatal food supplementation fortified with multiple micronutrients increases birth length: a randomized controlled trial in rural Burkina Faso
    Lieven Huybregts
    Department of Food Safety and Food Quality, Ghent University, Ghent, Belgium
    Am J Clin Nutr 90:1593-600. 2009
    ..Prenatal multiple micronutrient (MMN) or balanced energy and protein supplementation has a limited effect on birth size of the offspring...
  19. ncbi Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients
    J M Bourre
    French Academy of Medicine INSERM, U705 CNRS, UMR 7157 Universités Paris 7 et 5, Department of Neuro pharmaco nutrition Hôpital Fernand Widal, 200, rue du Faubourg Saint Denis, 75475 Paris Cedex 10
    J Nutr Health Aging 10:377-85. 2006
    ..In fact, most micronutrients (vitamins and trace-elements) have been directly evaluated in the setting of cerebral functioning...
  20. ncbi Abdominal obesity explains the positive rural-urban gradient in the prevalence of the metabolic syndrome in Benin, West Africa
    Gervais Ntandou
    TRANSNUT, WHO Collaborating Centre on Nutrition Changes and Development, Department of Nutrition, Universite de Montreal, Montreal H3C 3J7, Canada
    Nutr Res 29:180-9. 2009
    ..This study shows that the nutrition transition is ongoing in Benin and suggests that cardiovascular disease risk could be reduced substantially by promoting physical activity and a more adequate diet...
  21. pmc Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysis
    Prakesh S Shah
    Department of Paediatrics, Mount Sinai Hospital, University of Toronto, Ont
    CMAJ 180:E99-108. 2009
    Reduced intake of micronutrients during pregnancy exposes women to nutritional deficiencies and may affect fetal growth...
  22. ncbi Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: a cluster-randomised trial
    Sajid Soofi
    Department of Paediatrics and Child Health, Division of Women and Child Health, The Aga Khan University, Karachi, Pakistan
    Lancet 382:29-40. 2013
    Powders containing iron and other micronutrients are recommended as a strategy to prevent nutritional anaemia and other micronutrient deficiencies in children...
  23. ncbi Impact of nutritional status on antibody responses to different vaccines in undernourished Gambian children
    S E Moore
    MRC Keneba, MRC Laboratories, The Gambia
    Acta Paediatr 92:170-6. 2003
    ..To test the efficacy of T-cell-dependent and T-cell-independent vaccines in rural Gambian children suffering from a range of energy/protein and micronutrient deficiencies...
  24. ncbi Nutritional status of primary schoolchildren in Garhwali Himalayan villages of India
    Akoto Osei
    Helen Keller International, Asia Pacific Regional Office, Phnom Penh, Cambodia
    Food Nutr Bull 31:221-33. 2010
    ..However, past studies have narrowly focused on only a few micronutrients and have not carefully evaluated the association between sociodemographic factors and nutritional status of ..
  25. pmc Nutritional deficiencies in obesity and after bariatric surgery
    Stavra A Xanthakos
    Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2010, Cincinnati, OH 45229, USA
    Pediatr Clin North Am 56:1105-21. 2009
    ..This article reviews current knowledge of nutritional deficits in obese and overweight individuals and those that commonly present after bariatric surgery and summarizes current recommendations for screening and supplementation...
  26. pmc Interactions of malnutrition and immune impairment, with specific reference to immunity against parasites
    S Hughes
    Tropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia
    Parasite Immunol 28:577-88. 2006
    ..2. There is good evidence that specific micronutrients influence immunity, particularly zinc and vitamin A...
  27. pmc Do dietary supplements improve micronutrient sufficiency in children and adolescents?
    Regan L Bailey
    Office of Dietary Supplements, National Institutes of Health, Bethesda, MD 20892 7517, USA
    J Pediatr 161:837-42. 2012
    ..To examine if children use supplements to fill gaps in nutritionally inadequate diets or whether supplements contribute to already adequate or excessive micronutrient intakes from foods...
  28. ncbi Importance of zinc in the elderly: the ZENITH study
    N Meunier
    Centre de Recherche en Nutrition Humaine d Auvergne, Unite Maladies Metaboliques et Micronutriments, Centre de Recherche INRA Clermont Ferrand Theix, Saint Genes Champanelle, France
    Eur J Clin Nutr 59:S1-4. 2005
    ..This article reviews the importance of zinc (Zn) in elderly people, particularly for behavioural and mental function, micronutrient status, immune and antioxidant system, and bone metabolism...
  29. ncbi Antenatal supplementation with micronutrients and biochemical indicators of status and subclinical infection in rural Nepal
    Parul Christian
    Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Am J Clin Nutr 83:788-94. 2006
    ..Previously we showed that women in rural Nepal experience multiple micronutrient deficiencies in early pregnancy...
  30. pmc Rapeseed oil fortified with micronutrients reduces atherosclerosis risk factors in rats fed a high-fat diet
    Jiqu Xu
    Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan, PR China
    Lipids Health Dis 10:96. 2011
    b>Micronutrients polyphenols, tocopherols and phytosterols in rapeseed exert potential benefit to cardiovascular system, but most of these micronutrients are removed by the refining process...
  31. ncbi Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part II--vitamin D, vitamin A, iron, zinc, iodine, essential fatty acids
    Joe Leigh Simpson
    Florida International University, College of Medicine, Miami, FL 33199, USA
    J Matern Fetal Neonatal Med 24:1-24. 2011
    Part II of this review considers additional micronutrients. Vitamin D is a fat soluble vitamin found in foods of animal origins (fatty fish, liver oil) or fortified products (milk, cheese)...
  32. ncbi Micronutrient status of primary school girls in rural and urban areas of South Vietnam
    Thi Tuyet Mai Ta
    Department of Food and Nutrition, Japan Women s University, Tokyo, Japan
    Asia Pac J Clin Nutr 12:178-85. 2003
    ..Thus, nutritional education to improve the dietary habits of the two groups is necessary for Vietnamese primary school children...
  33. ncbi Monitoring the marketing, distribution, and use of Sprinkles micronutrient powders in rural western Kenya
    Parminder S Suchdev
    Nutrition Branch, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS K25, Atlanta, GA 30341, USA
    Food Nutr Bull 31:S168-78. 2010
    ....
  34. ncbi Food groups associated with a composite measure of probability of adequate intake of 11 micronutrients in the diets of women in urban Mali
    Gina Kennedy
    Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands
    J Nutr 140:2070S-8S. 2010
    ..Despite this, there are little data on the dietary intake of micronutrients among women of reproductive age in Mali...
  35. ncbi Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery
    Barbara Ernst
    Interdisciplinary Obesity Center, Kantonsspital St Gallen, CH 9400, Rorschach, Switzerland
    Obes Surg 19:66-73. 2009
    ..Increasing evidence points to a generally poor micronutrient status in obese subjects...
  36. ncbi Triple trouble: the role of malnutrition in tuberculosis and human immunodeficiency virus co-infection
    Monique van Lettow
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nutr Rev 61:81-90. 2003
    ..Further investigation is needed to evaluate the prophylactic and therapeutic potential of nutritional interventions for co-infection with HIV and tuberculosis...
  37. pmc Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians
    Davidson H Hamer
    Jean Mayer USDA Human Nutrition Research Center on the Aging, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA
    J Nutr 139:113-9. 2009
    ..Deficiencies of essential vitamins and minerals place these elderly adults at risk for infections through their negative impact on immune function...
  38. ncbi Impact of multiple micronutrient versus iron-folic acid supplements on maternal anemia and micronutrient status in pregnancy
    Lindsay H Allen
    U S Department of Agriculture, ARS Western Human Nutrition Research Center, University of California, Davis, California, USA
    Food Nutr Bull 30:S527-32. 2009
    ..Multiple micronutrient supplements could increase hemoglobin and improve micronutrient status of pregnant women more than iron supplements alone or iron with folic acid...
  39. ncbi Preventing low birthweight through maternal multiple micronutrient supplementation: a cluster-randomized, controlled trial in Indramayu, West Java
    - Sunawang
    Center for Health Research, School of Public Health, University of Indonesia, Depok, Indonesia
    Food Nutr Bull 30:S488-95. 2009
    ..UNICEF/United Nations University/World Health Organization jointly proposed a formulation for a multiple micronutrient supplement for pregnant women, and several effectiveness trials were conducted to assess its impact...
  40. ncbi Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus
    Maria Kippler
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Toxicol Lett 192:162-8. 2010
    ..study was to elucidate to what extent the accumulation of Cd in human placenta interacts with the transport of micronutrients to the fetus...
  41. ncbi Association between protein intake and blood pressure: the INTERMAP Study
    Paul Elliott
    Department of Epidemiology and Public Health, Faculty of Medicine, St Mary s Campus, Imperial College London, London, England
    Arch Intern Med 166:79-87. 2006
    ..Findings from epidemiological studies suggest an inverse relationship between individuals' protein intake and their blood pressure...
  42. ncbi Risk of zinc, iodine and other micronutrient deficiencies among school children in North East Thailand
    R A Thurlow
    Department of Human Nutrition, University of Otago, New Zealand
    Eur J Clin Nutr 60:623-32. 2006
    ....
  43. pmc Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial
    Sunil Sazawal
    Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    PLoS ONE 5:e12167. 2010
    ..from a community based double-masked, randomized trial among children 1-4 years evaluating the effects of micronutrients (especially of zinc and iron) delivered through fortified milk on growth, anemia and iron status markers as ..
  44. ncbi Programs to improve production and consumption of animal source foods and malnutrition in Vietnam
    Le Thi Hop
    National Institute of Nutrition, Ministry of Health, Hanoi, Vietnam
    J Nutr 133:4006S-4009S. 2003
    ..The prevalence of undernutrition in children <5 y old, and of chronic energy deficiency (CED) in women of reproductive age, has been remarkably reduced...
  45. pmc Creatinine, diet, micronutrients, and arsenic methylation in West Bengal, India
    Arin Basu
    Arsenic Health Effects Research Group, School of Public Health, University of California, Berkeley, California 94720, USA
    Environ Health Perspect 119:1308-13. 2011
    ..Methylation may have an important role in arsenic toxicity, because the monomethylated trivalent metabolite [MMA(III)] is highly toxic...
  46. ncbi Milk products, dietary patterns and blood pressure management
    Penny M Kris-Etherton
    Department of Nutritional Sciences, 110 Chandlee Laboratory, Penn State University, University Park, PA 16802, USA
    J Am Coll Nutr 28:103S-19S. 2009
    ..A growing evidence base shows that dairy product consumption is involved in the regulation of BP. Consequently, inclusion of dairy products in a heart healthy diet is an important focal point to attain BP benefits...
  47. ncbi Simultaneous weekly supplementation of iron and zinc is associated with lower morbidity due to diarrhea and acute lower respiratory infection in Bangladeshi infants
    Abdullah H Baqui
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Nutr 133:4150-7. 2003
    ..Intermittent simultaneous supplementation with iron + zinc seems promising; it will be useful to determine whether higher doses would provide greater benefits...
  48. ncbi Breeding for micronutrients in staple food crops from a human nutrition perspective
    Ross M Welch
    USDA ARS, US Plant, Soil and Nutrition Laboratory, Cornell University, Tower Road, Ithaca, NY 14853 0001, USA
    J Exp Bot 55:353-64. 2004
    ..Importantly, these crops can be enriched (i.e. 'biofortified') with micronutrients using plant breeding and/or transgenic strategies, because micronutrient enrichment traits exist within their ..
  49. ncbi Physiological functions of mineral micronutrients (Cu, Zn, Mn, Fe, Ni, Mo, B, Cl)
    Robert Hansch
    Institut fur Pflanzenbiologie, Technische Universitat Braunschweig, Braunschweig, Germany
    Curr Opin Plant Biol 12:259-66. 2009
    b>Micronutrients are involved in all metabolic and cellular functions...
  50. ncbi Placing metal micronutrients in context: transport and distribution in plants
    Sergi Puig
    Departament de Bioquimica i Biologia Molecular, Universitat de Valencia, Valencia, Spain
    Curr Opin Plant Biol 12:299-306. 2009
    ..developed finely tuned mechanisms to efficiently acquire and balance the concentrations of essential metal micronutrients including iron, zinc, copper, and manganese, both at the cellular and systemic levels...
  51. ncbi Indicators of zinc status at the population level: a review of the evidence
    Rosalind S Gibson
    Department of Hunan Nutrition, University of Otago, Union Street, PO Box 56, Dunedin 9015, New Zealand
    Br J Nutr 99:S14-23. 2008
    ..More research is needed to establish the validity, specificity, sensitivity, and feasibility of these new biomarkers, especially in community-settings...
  52. ncbi Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development
    Seth Adu-Afarwuah
    Program in International Nutrition and Community Nutrition, University of California, Davis, CA 95616 8669, USA
    Am J Clin Nutr 86:412-20. 2007
    ..A potential low-cost solution is the home fortification of complementary foods with Sprinkles (SP) powder, crushable Nutritabs (NT) tablets, or energy-dense (108 kcal/d), fat-based Nutributter (NB)...
  53. pmc Associations between body mass index and the prevalence of low micronutrient levels among US adults
    Joel E Kimmons
    Division of Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    MedGenMed 8:59. 2006
    ..Low micronutrient levels observed with increasing adiposity may result from inadequate nutrient intake and/or alterations in nutrient metabolism...
  54. ncbi A randomized trial of multivitamin supplements and HIV disease progression and mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:23-32. 2004
    ..Results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (HIV) disease...
  55. ncbi Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal
    Parul Christian
    Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room W2041, Baltimore, MD 21205, USA
    JAMA 304:2716-23. 2010
    ..Few studies have examined whether iron and zinc supplementation during gestation, a critical period of central nervous system development, affects children's later functioning...
  56. ncbi Moving micronutrients from the soil to the seeds: genes and physiological processes from a biofortification perspective
    Brian M Waters
    Department of Agronomy and Horticulture, University of Nebraska, Lincoln, NE 68583 0915, USA
    Plant Sci 180:562-74. 2011
    The micronutrients iron (Fe), zinc (Zn), and copper (Cu) are essential for plants and the humans and animals that consume plants...
  57. ncbi Cadmium interacts with the transport of essential micronutrients in the mammary gland - a study in rural Bangladeshi women
    Maria Kippler
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Toxicology 257:64-9. 2009
    ..study was to elucidate how cadmium is transported to breast milk by assessing interactions with essential micronutrients. The study is nested into a food and micronutrient supplementation trial conducted among pregnant women in ..
  58. ncbi Maternal micronutrient deficiency, fetal development, and the risk of chronic disease
    Parul Christian
    Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21200, USA
    J Nutr 140:437-45. 2010
    ..This review fills a critical gap in the literature related to the seminal role of micronutrients in early life and extends the discussion on the developmental origins of health and disease beyond birth size ..
  59. ncbi Effects of prenatal multimicronutrient supplements on birth weight and perinatal mortality: a randomised, controlled trial in Guinea-Bissau
    P Kaestel
    Department of Human Nutrition, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Eur J Clin Nutr 59:1081-9. 2005
    ..To assess the effects of daily prenatal multimicronutrient supplementation on birth weight (BW) and perinatal mortality...
  60. pmc Micronutrient deficiencies and cognitive functioning
    Maureen M Black
    Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Nutr 133:3927S-3931S. 2003
    ..Although micronutrient deficiencies often co-occur in the context of poverty, little is known about the impact of multiple micronutrient deficiencies on cognitive development...
  61. ncbi Trends in energy and nutrient intake and risk of inadequate intakes in Catalonia, Spain (1992-2003)
    Lluis Serra-Majem
    Community Nutrition Research Centre, University of Barcelona Science Park, Baldiri Reixac 4, Torre D 4A1, 08028, Barcelona, Spain
    Public Health Nutr 10:1354-67. 2007
    ..To analyse trends in energy and nutrient intakes and nutritional adequacy from 1992 to 2003...
  62. ncbi Low plasma selenium concentrations, high plasma human immunodeficiency virus load and high interleukin-6 concentrations are risk factors associated with anemia in adults presenting with pulmonary tuberculosis in Zomba district, Malawi
    M Van Lettow
    Johns Hopkins University School of Medicine, Baltimore, USA
    Eur J Clin Nutr 59:526-32. 2005
    ..Although anemia is common among adults with pulmonary tuberculosis and human immunodeficiency virus (HIV) infection in sub-Saharan Africa, the factors contributing to its pathogenesis have not been well characterized...
  63. ncbi Prevalence of micronutrient malnutrition worldwide
    Usha Ramakrishnan
    Department of International Health, Rollins School of Public Health at Emory University, Atlanta, GA 30032, USA
    Nutr Rev 60:S46-52. 2002
    ..Finally, in many settings, more than one micronutrient deficiency exists, suggesting the need for simple approaches that evaluate and address multiple micronutrient malnutrition...
  64. ncbi Micronutrients and the pathogenesis of human immunodeficiency virus infection
    R D Semba
    Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Br J Nutr 81:181-9. 1999
    ..Insufficient dietary intake, malabsorption, diarrhoea, and impaired storage and altered metabolism of micronutrients can contribute to the development of micronutrient deficiencies...
  65. pmc Mapping low intake of micronutrients across Europe
    G B M Mensink
    Department of Epidemiology and Health Monitoring, Robert Koch Institute, General Pape Strasse 64, DE 12101 Berlin, Germany
    Br J Nutr 110:755-73. 2013
    ..In spite of the limitations of the data, the present study provides valuable new information about micronutrient intakes across Europe and the likelihood of inadequacy country by country...
  66. ncbi Micronutrients in childhood and the influence of subclinical inflammation
    David I Thurnham
    Kenya Medical Research Institute, Centre for Public Health Research, Nairobi
    Proc Nutr Soc 64:502-9. 2005
    ..The inflammatory response rapidly influences the concentration in the blood of several important micronutrients such as vitamin A, Fe and Zn, even in the first 24 h, whereas dietary deficiencies can be envisaged as having ..
  67. pmc Dietary intake of meat, fruits, vegetables, and selective micronutrients and risk of bladder cancer in the New England region of the United States
    J W Wu
    National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, Rockville, MD 20852, USA
    Br J Cancer 106:1891-8. 2012
    ..Despite many studies on diet and bladder cancer, there are areas that remain unexplored including meat mutagens, specific vegetable groups, and vitamins from diet...
  68. ncbi The role of diet and nutrient composition in nonalcoholic Fatty liver disease
    Erin Marie McCarthy
    Northwestern Faculty Foundation, Chicago, IL, USA
    J Acad Nutr Diet 112:401-9. 2012
    ....
  69. pmc Micronutrients, N-acetyl cysteine, probiotics and prebiotics, a review of effectiveness in reducing HIV progression
    Ruben Hummelen
    Department of Public Health, Erasmus MC University Medical Center Rotterdam P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Nutrients 2:626-51. 2010
    Low serum concentrations of micronutrients, intestinal abnormalities, and an inflammatory state have been associated with HIV progression. These may be ameliorated by micronutrients, N-acetyl cysteine, probiotics, and prebiotics...
  70. pmc Plasma pencil atmospheric mass spectrometry detection of positive ions from micronutrients emitted from surfaces
    M Jeanette Stein
    Department of Bioengineering, University of Washington, Seattle, Washington 98195 5061, USA
    Anal Chem 84:1572-8. 2012
    Analysis and detection of micronutrients is important for the reduction of the global burden of malnutrition-related disease...
  71. ncbi Is maternal education level associated with diet in 10-year-old children?
    Victoria L Cribb
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    Public Health Nutr 14:2037-48. 2011
    ..To examine the associations between maternal education level and diet in 10-year-old children...
  72. ncbi Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study
    N I Weijl
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Cancer 40:1713-23. 2004
    ..However, patients who achieved the highest plasma concentrations of the three antioxidant micronutrients had significantly less loss of high-tone hearing...
  73. pmc Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa
    M K Chhagan
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Private Bag 7, Congella, 4013, South Africa
    Eur J Clin Nutr 63:850-7. 2009
    The efficacy of zinc combined with vitamin A or multiple micronutrients in preventing diarrhoea is unclear in African countries with high prevalence of human immunodeficiency virus (HIV)-exposed children...
  74. ncbi Fortification strategies to meet micronutrient needs: successes and failures
    Ian Darnton-Hill
    World Health Organization, Geneva, Switzerland
    Proc Nutr Soc 61:231-41. 2002
    ..Food fortification based on sound principles and supported by clear policies and regulations can play an increasingly large role in this progress towards prevention and control of micronutrient malnutrition...
  75. ncbi Recommendations for improving Guatemala's food fortification program based on household income and expenditure survey (HIES) data
    John L Fiedler
    Harvest Plus, International Food Policy Research Institute, Washington DC, USA
    Food Nutr Bull 31:251-69. 2010
    ..In countries that have fortification, governments are increasingly being challenged to provide evidence that programs are well designed and effective...
  76. pmc Zinc and glutamine improve brain development in suckling mice subjected to early postnatal malnutrition
    Fernando V L Ladd
    Department of Surgery, College of Veterinary Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
    Nutrition 26:662-70. 2010
    ..The effect of zinc and glutamine on brain development was investigated during the lactation period in Swiss mice...
  77. ncbi How is the adequacy of micronutrient intake assessed across Europe? A systematic literature review
    Garden Tabacchi
    Institute of Physiology and Human Nutrition, University of Palermo, Palermo, Italy
    Br J Nutr 101:S29-36. 2009
    ..The aims of the present paper were to review the methods used for the adequacy assessment of the intake of six micronutrients of public health concern (vitamin A, folate, vitamin B12, Fe, Zn and iodine) in non-European and European ..
  78. ncbi Micronutrients and fetal growth
    Caroline H D Fall
    MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, Hampshire SO16 6YD, United Kingdom
    J Nutr 133:1747S-1756S. 2003
    ..b>Micronutrients are essential for growth, and maternal micronutrient deficiency, frequently multiple in developing countries, ..
  79. ncbi [Micronutrients and their relevance for the eye--function of lutein, zeaxanthin and omega-3 fatty acids]
    F J Schweigert
    Institut für Ernährungswissenschaft, Universitat Potsdam, Arthur Scheunert Allee 114 116, Nuthetal
    Klin Monbl Augenheilkd 228:537-43. 2011
    b>Micronutrients play an important role in function and health maintenance for the eye...
  80. ncbi Iron, folate, and vitamin B12 stores among pregnant women in a rural area of Haryana State, India
    Priyali Pathak
    Department of Human Nutrition, All India Institute of Medical Sciences, New Delhi, India
    Food Nutr Bull 28:435-8. 2007
    ..Iron, folate, and vitamin B12 deficiencies have adverse effects on pregnancy outcome. In India, data on the concomitant prevalence of these deficiencies among pregnant women are meager...
  81. ncbi Lessons learned from national food fortification projects: experiences from Morocco, Uzbekistan, and Vietnam
    James P Wirth
    Global Alliance for Improved Nutrition GAIN, P O Box 55, Geneva 1211, Switzerland
    Food Nutr Bull 33:S281-92. 2012
    ..With the increased number of fortification projects globally, there is a need to share practical lessons learned relating to their implementation and responses to project-related and external challenges...
  82. ncbi Intake of milk with added micronutrients increases the effectiveness of an energy-restricted diet to reduce body weight: a randomized controlled clinical trial in Mexican women
    Jorge L Rosado
    Human Nutrition Department, School of Natural Sciences, Universidad Autónomade Querétaro, Queretaro, Mexico
    J Am Diet Assoc 111:1507-16. 2011
    ..Micronutrient deficiencies have been associated with an increase in fat deposition and body weight; thus, adding them to low-fat milk may facilitate weight loss when accompanied by an energy-restricted diet...
  83. ncbi Dietary diversification/modification strategies to enhance micronutrient content and bioavailability of diets in developing countries
    R S Gibson
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand
    Br J Nutr 85:S159-66. 2001
    Both cereal staples and household diets can be manipulated to enhance the content of micronutrients and/or alter the levels of absorption modifiers to improve micronutrient bioavailability...
  84. ncbi Micronutrients, birth weight, and survival
    Parul Christian
    Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Annu Rev Nutr 30:83-104. 2010
    ..Few other single micronutrients given antenatally, including vitamin A, zinc, and folic acid, have been systematically shown to confer such a ..
  85. ncbi The overlap of overweight and anaemia among women in three countries undergoing the nutrition transition
    C L Eckhardt
    Food Consumption and Nutrition Division, International Food Policy Research Institute, Washington, DC 20006, USA
    Eur J Clin Nutr 62:238-46. 2008
    ..To compare the odds of anaemia in overweight and obese (OVWT) (body mass index (BMI) > or =25) versus non-overweight (non-OVWT) (BMI<25) women in three countries at different stages of the nutrition transition...
  86. ncbi Urbanisation, nutrition transition and cardiometabolic risk: the Benin study
    Helene Delisle
    Department of Nutrition, Faculty of Medicine, TRANSNUT, WHO Collaborating Centre on Nutrition Changes and Development, University of Montreal, PO Box 6128, Downtown Station, Montreal, PQ, Canada H3C 3J7
    Br J Nutr 107:1534-44. 2012
    ..This risk could be mitigated by a more adequate diet, particularly micronutrient intake, and a more active lifestyle...
  87. ncbi Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmic Epidemiol 14:288-98. 2007
    ..Results of observational and intervention studies have been inconsistent...
  88. ncbi The influence and benefits of controlling for inflammation on plasma ferritin and hemoglobin responses following a multi-micronutrient supplement in apparently healthy, HIV+ Kenyan adults
    Anne S W Mburu
    Kenya Medical Research Institute, Centre for Public Health Research, Nairobi, 00202 Kenya
    J Nutr 138:613-9. 2008
    ..However, low hemoglobin concentrations were the consequence of long-term chronic inflammation and improvements in response to MN supplements were only detected in subjects with no inflammation...
  89. pmc The gastric sleeve: losing weight as fast as micronutrients?
    Edo O Aarts
    Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands
    Obes Surg 21:207-11. 2011
    ..However, the incidence of micronutrient deficiencies after LSG have hardly been researched...
  90. ncbi Associations between added sugars and micronutrient intakes and status: further analysis of data from the National Diet and Nutrition Survey of Young People aged 4 to 18 years
    Sigrid Gibson
    Sig Nurture Ltd, 11 Woodway, Guildford, Surrey GU1 2TF, UK
    Br J Nutr 101:100-7. 2009
    ..Further work is needed to explore the impact of different sources of added sugars and to refine assessments of inadequate intakes and status...
  91. ncbi Micronutrient deficiencies and anemia among preschool children in rural Vietnam
    Nguyen Van Nhien
    Department of Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770 8503, Japan
    Asia Pac J Clin Nutr 17:48-55. 2008
    ..In addition, the results also demonstrate a strong relationship between selenium deficiency and anemia. Clearly, sustainable strategies are urgently required to overcome the problems in the country...
  92. pmc Multiple micronutrient supplementation during pregnancy in low-income countries: a meta-analysis of effects on stillbirths and on early and late neonatal mortality
    Carine Ronsmans
    London School of Hygiene and Tropical Medicine, London, UK
    Food Nutr Bull 30:S547-55. 2009
    ..Multiple micronutrient deficiencies are common among women in low-income countries and may adversely affect pregnancy outcomes...
  93. ncbi Multiple micronutrient supplementation during pregnancy in developing-country settings: policy and program implications of the results of a meta-analysis
    Roger Shrimpton
    Institute of Child Health, London, UK
    Food Nutr Bull 30:S556-73. 2009
    An independent Systematic Review Team performed a meta-analysis of 12 randomized, controlled trials comparing multiple micronutrients with daily iron-folic acid supplementation during pregnancy.
  94. ncbi Effect of vitamin supplementation to HIV-infected pregnant women on the micronutrient status of their infants
    A Baylin
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Eur J Clin Nutr 59:960-8. 2005
    ....
  95. pmc Both human immunodeficiency virus-infected and human immunodeficiency virus-exposed, uninfected children living in Brazil, Argentina, and Mexico have similar rates of low concentrations of retinol, beta-carotene, and vitamin E
    Jacqueline P Monteiro
    University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Nutr Res 29:716-22. 2009
    ..Our hypothesis was that the rates of low concentrations of these micronutrients would be higher in the HIV-infected group than those in the HIV-exposed, uninfected group...
  96. ncbi Effect of long-term calorie restriction with adequate protein and micronutrients on thyroid hormones
    Luigi Fontana
    Washington University School of Medicine, 4566 Scott Avenue, Campus Box 8113, St Louis, MO 63110, USA
    J Clin Endocrinol Metab 91:3232-5. 2006
    ..Caloric restriction (CR) retards aging in mammals. It has been hypothesized that a reduction in T(3) hormone may increase life span by conserving energy and reducing free-radical production...
  97. pmc Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage
    Bruce N Ames
    Nutrition and Metabolism Center, Children s Hospital of Oakland Research Institute, Oakland, CA 94609, USA
    Proc Natl Acad Sci U S A 103:17589-94. 2006
    ..Deficiencies in many micronutrients cause DNA damage, such as chromosome breaks, in cultured human cells or in vivo...
  98. pmc Dietary supplement use in the United States, 2003-2006
    Regan L Bailey
    National Institutes of Health, Office of Dietary Supplements, Bethesda, MD 20892 7517, USA
    J Nutr 141:261-6. 2011
    ..Given the widespread use of supplements, data should be included with nutrient intakes from foods to correctly determine total nutrient exposure...
  99. ncbi DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
    B N Ames
    University of California, 94720 3202, Berkeley, CA, USA
    Mutat Res 475:7-20. 2001
    A deficiency of any of the micronutrients: folic acid, Vitamin B12, Vitamin B6, niacin, Vitamin C, Vitamin E, iron, or zinc, mimics radiation in damaging DNA by causing single- and double-strand breaks, oxidative lesions, or both...
  100. ncbi Micronutrients in women's health and immune function
    A Bendich
    GlaxoSmithKline Consumer Healthcare, 1500 Littleton Road, Parsippany, NJ 07054 3884, USA
    Nutrition 17:858-67. 2001
    ..b>Micronutrients of particular importance for prevention of adverse pregnancy outcomes are folic acid, zinc, and iron...
  101. ncbi Effects of maternal multimicronutrient supplementation on the mental development of infants in rural western China: follow-up evaluation of a double-blind, randomized, controlled trial
    Qiang Li
    Division of Epidemiology and Biostatistics, Department of Public Health, Xi an Jiaotong University School of Medicine, 76 Yanta West Rd, Xi an 710061, China
    Pediatrics 123:e685-92. 2009
    ..We investigated the benefits of maternal multimicronutrient supplementation during gestation on the mental and psychomotor development of infants...

Research Grants65

  1. MICRONUTRIENTS AND ENTERIC INFECTION IN AFRICAN CHILDREN
    Sherwood Gorbach; Fiscal Year: 2005
    ..This study will also allow us to determine risk factors for persistent diarrhea, and to develop algorithms for the management of infectious diarrhea in a region where HIV infection is common. ..
  2. METABOLISM, MICRONUTRIENTS, AND ANTIRETROVIRAL THERAPY OUTCOMES IN ZAMBIA
    DOUGLAS CORBETT HEIMBURGER; Fiscal Year: 2010
    ..measure additional metabolic analytes (sodium, chloride, bicarbonate, urea nitrogen, and creatinine), selected micronutrients (ferritin for iron status, folic acid, vitamins A, B12, and E, and selenium), and inflammatory markers (C-..
  3. Preconception Nutrition, Endocrine Disruptors, Reproductive Outcomes
    Xiaobin Wang; Fiscal Year: 2013
    ..and birth outcomes (gestational age, birth weight, length, and head circumference);(3) Preconception BMI and Micronutrients: including serum biomarkers of folate, B6, B12, cysteine, homocysteine, hemoglobin, ferritin, and trans-..
  4. Triple Quadrupole/Linear Ion Trap LC-MS/MS for LPI
    Jan Frederik Stevens; Fiscal Year: 2010
    ..The LPI has established itself as a national and international leader in research and education on micronutrients and antioxidants, and is one of a few research centers in the US to focus entirely on increasing human "..
  5. The Magnesium and Metabolic Syndrome Trial
    Stella Lucia Volpe; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Many people consume processed foods, leading to decreased consumption of important micronutrients, such as magnesium;these same individuals might be adherent to magnesium supplementation, even though dietary ..
  6. Lung Cancer Chemoradiation: Predictors of Survival
    Xifeng Wu; Fiscal Year: 2009
    ..such as smoking at diagnosis and treatment initiation, demographic factors, poor dietary intake of select micronutrients, weight loss, performance status, and tumor characteristics - with the genetic data from the studies described ..
  7. Prenatal diet, PM2.5 and programming of the infant autonomic response
    Rosalind J Wright; Fiscal Year: 2013
    ..g., ?-3 fatt acids and antioxidant micronutrients (e.g...
  8. Mycobacterium turberculosis metal transport P-type ATPases
    JOSE M ARGUELLO; Fiscal Year: 2010
    ..Host defense includes reactive oxygen species, reactive nitrogen species, removal of metal micronutrients and lowered pH. The microorganism survives, in part, by secreting various metalloenzymes (SODs, catalases, etc...
  9. Regulation of vitamin A metabolism during Schistosoma mansoni infection
    PNG LOKE; Fiscal Year: 2013
    ..b>Micronutrients such as vitamin A may play a critical role in regulating the inflammatory immune response during helminth ..
  10. The role of b-carotene in maternal-fetal nutrition
    Loredana Quadro; Fiscal Year: 2013
    ..These studies have a significant impact on human health, since they aim at reducing the incidence of fetal malformations associated with an abnormal maternal intake of micronutrients, such as vitamins.
  11. A Pilot Study of the DASH Diet in Not-Well-Controlled Adult Asthma
    Jun Ma; Fiscal Year: 2013
    ..resulted in a chronic metabolic surplus and a relative reduction in the intake of complex carbohydrates and micronutrients. The available literature on the relationship between diet and asthma has taken a reductionist approach by ..
  12. Malaria in Pregnancy: Nutrition and Immunologic Effects
    Wafaie W Fawzi; Fiscal Year: 2013
    ..The published literature suggests that these two micronutrients favor a reduction in risk of placental malaria and related clinical outcomes including malaria and anemia ..
  13. Nutritional Epidemiology of Lower Urinary Tract Symptoms
    Nancy Nairi Maserejian; Fiscal Year: 2010
    ..It also examines dietary versus supplemental sources of micronutrients and dose-response trends across categories of intake...
  14. CER on CAM Antioxidant Therapies (CERCAT)
    BALZ B FREI; Fiscal Year: 2012
    ..Pauling Institute has established itself as a national and international leader in research and education on micronutrients and antioxidants, and is one of a few research centers in the U.S...
  15. International Population Study on Macronutrients and BP - INTERMAP
    LINDA VERNER VAN HORN; Fiscal Year: 2013
    ..INTERMAP is a basic epidemiologic investigation on the role of dietary factors (foods/macro-/micronutrients)/ their urinary metabolites in the etiopatho- genesis population-wide of unfavorable BP levels, including the ..
  16. DIETARY PREVENTION OF CARDIAC MITOCHONDRIAL AGING
    Tory M Hagen; Fiscal Year: 2011
    ..The long-term objectives of this research are to examine the causes and consequences of mitochondrial decay and how the micronutrients acetyl-L-carnitine and/or (R)-a-lipoic acid may maintain mitochondrial function during aging.
  17. Oxidative Stree, Antioxidants and Risk of Breast Cancer: A Prospective Analysis
    A Heather Eliassen; Fiscal Year: 2012
    ..Carotenoids, prominent micronutrients in fruits and vegetables, have been of specific interest in breast cancer because of their antioxidant ..
  18. Increasing Animal Foods in Diets of HIV-Infected Kenyan Women and Their Children
    Judith A Ernst; Fiscal Year: 2011
    In the proposed project we will evaluate the effect of protein and micronutrients in meat on the health and nutritional well being of rural Kenyan women living with HIV and the health and development of their children, by means of a ..
  19. Maternal Methylmercury Exposure Through Rice Ingestion and Offspring Development
    SARAH ROTHENBERG; Fiscal Year: 2013
    ..This study will examine methylmercury exposure in the absence of the same beneficial micronutrients associated with fish ingestion...
  20. Complementary feeding: a Global Network cluster randomized controlled trial
    K Michael Hambidge; Fiscal Year: 2012
    ..plant-based complementary foods, even prepared optimally, cannot meet the needs for certain 'problem'micronutrients. Of special importance are iron and zinc, requirements for which can only be attained from unfortified foods ..
  21. Long-Term Dietary Risk Factor Assessment and Incident AD
    MARTHA MORRIS; Fiscal Year: 2009
    ..Others propose that the mechanism for protection by these micronutrients may be through reduction in the accumulation of homocysteine...
  22. Nutrition and HIV Progression
    Christine A Wanke; Fiscal Year: 2013
    ..There are data that suggest that the use of micronutrients could reduce CD4 count decline and delay death, however micronutrients alone will not support or maintain ..
  23. Renal blood flow, vascular stiffness, and the DASH diet
    Paul R Conlin; Fiscal Year: 2012
    ..I was a co-investigator in three interventional nutrition studies that explored the effects of macro- and micronutrients on blood pressure...
  24. Molecular Aspects of Copper Binding to the Prion Protein
    Glenn L Millhauser; Fiscal Year: 2013
    ..This research is aimed at evaluating proteins of the central nervous system that regulate copper and other micronutrients. These proteins are essential for neuron health and understanding their behavior will lead to new strategies ..
  25. Vascular Quiescence and Stabilization in Immunity
    Theresa T Lu; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Lymph node blood vessels bring cells, oxygen, and micronutrients to the lymph node and are a critical component of a functioning immune system...
  26. The Biological Role of Heme in Nutrition
    Iqbal Hamza; Fiscal Year: 2013
    ..Results from our studies may provide a heuristic paradigm to tackle similar questions for other micronutrients.
  27. Dietary Methyl Content, Epigenetics and Breast Cancer
    Jia Chen; Fiscal Year: 2010
    ..Specifically, we will examine the dietary intake of one-carbon-related micronutrients/compounds (e.g...
  28. Effects of protein-calorie supplementation on HIV disease in breastfeeding women
    C Fordham von Reyn; Fiscal Year: 2013
    ..Existing research has focused on the role of micronutrients in HIV disease outcomes but has not addressed the role of protein calorie supplementation (PCS) in ..
  29. The MTHFR C677T SNP exerts bipolar effects on colorectal cancer risk through the
    Joel B Mason; Fiscal Year: 2010
    ..pathway as playing a large role in the modulation of carcinogenesis mediated by folate and the other 1-carbon micronutrients. The purpose of the proposed animal studies is to conduct the initial steps necessary to define the ..
  30. Epidemiology of Prenatal Factors and Adult Psychopathology
    ALAN STEWART BROWN; Fiscal Year: 2012
    ..by investigating their relationship with bipolar disorder;2) investigating whether specific prenatal micronutrients [vitamin B12, iron (ferritin), vitamin A (retinol)] are associated with an increased risk of adult ..
  31. Seasonal Impact of iron fortification on malaria incidence in Ghanaian children
    Stanley H Zlotkin; Fiscal Year: 2010
    ..the RFA by proposing the use of encapsulated ferrous fumarate, supplied in a powder form with other essential micronutrients as a potentially safer and effective alternative to syrups or drops for providing iron to infants and young ..
  32. MICRONUTRIENTS AND ENTERIC INFECTION IN AFRICAN CHILDREN
    MICHAEL BENNISH; Fiscal Year: 2002
    ..This study will also allow us to determine risk factors for persistent diarrhea, and to develop algorithms for the management of infectious diarrhea in a region where HIV infection is common. ..
  33. CALERIE Competitive Renewal
    William E Kraus; Fiscal Year: 2013
    ..However, there were also indications of malnutrition with deficiencies in many micronutrients. Beyond this experiment, most information comes from animal models, and significant CR benefits have been ..
  34. APOE and the Effects of Malnutrition on Cognitive and Intestinal Development
    Richard L Guerrant; Fiscal Year: 2010
    ..order to directly test our hypothesis that intestinal and cognitive impairments involve ApoE and that specific micronutrients can ameliorate these effects, and to examine potential mechanisms involved, we have established murine models ..
  35. The Genetic Basis of Natural Ionomic Variation
    Mary Lou Guerinot; Fiscal Year: 2013
    ..elemental- profile or "ionome" including P, Ca, K, Mg (macronutrients);Cu, Fe, Zn, Mn, Co, Ni, Se, Mo, I (micronutrients of significance to plant and human health);Na, As, and Cd (minerals causing agricultural or environmental ..
  36. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..The relationship between mastitis and breastmilk HIV load and the epidemiology and microbiology of mastitis will be examined in a new cohort of HIV-infected lactating women. ..
  37. Micronutrient Malnutrition and EBV Persistence in Children
    Rosemary Rochford; Fiscal Year: 2010
    ..We are testing the hypothesis that essential micronutrients are deficient in children that are living in a region in Kenya where there is a high risk for getting Burkitt&..
  38. Influence of Dietary Flavonoids on the Expression of At*
    Carl Keen; Fiscal Year: 2002
    ..Using the mouse model, they will test the hypothesis that a diet marginal in select micronutrients will induce a pro-oxidative state that will worsen the pathophysiological state of atherosclerosis...
  39. CHLAMYDIA TRACHOMATIS ENVELOPE COMPONENTS AND VIRULENCE
    JANE RAULSTON; Fiscal Year: 2003
    ..the endometrial epithelial cell layer lining the uterine cavity is subject to constant changes in levels of micronutrients such as iron, due to hormonal cycling during menstruation...
  40. OXIDATIVE CELL INJURY: FIRST-EPISODE PSYCHOTIC PATIENTS
    Sahebarao Mahadik; Fiscal Year: 2002
    ..Plasma levels of MDA, PLA2, nonenzymatic antioxidants (vitamins C and E, urate), and micronutrients (copper, zinc, selenium) that are involved in activities of antioxidant enzymes will also be determined...
  41. FAT SOLUBLE MICRONUTRIENTS IN HUMAN PLASMA AND TISSUES
    NORMAN KRINSKY; Fiscal Year: 1993
    ..of this proposal is to ascertain whether a relationship exists between plasma and tissue levels of fat-soluble micronutrients such as alpha-tocopherol and gamma-tocopherol and carotenoids such as beta- carotene, alpha-carotene, lycopene,..
  42. LOCALIZED VITAMIN DEFICIENCIES AND RISK FOR LUNG CANCER
    Chandrika Piyathilake; Fiscal Year: 2001
    ..effect of smoking to be greatest in the lung, where the potential for cigarette smoke to oxidize and destroy micronutrients should be most pronounced...
  43. C elegans:a model to study intestinal water-soluble vitamins transport in vivo
    HAMID SAID; Fiscal Year: 2007
    ..Humans cannot synthesize these micronutrients, and thus, must obtain them by intestinal absorption via the function of a number of specialized transporters...
  44. Induction Of Apoptosis in Osteosarcoma By Green Tea
    TARIQ HAQQI; Fiscal Year: 2005
    b>Micronutrients present in edible plants are known to possess anti-carcinogenic properties because epidemiological studies have suggested that consumption of fruits and vegetables may prevent against many cancer types...
  45. EVALUATION OF INTESTINAL ABSORPTION OF BETA-CAROTENE
    Sohrab Mobarhan; Fiscal Year: 1990
    ..Subsequently, the macro- and micronutrients in rectal effluent are measured. This method avoids some of the difficulties inherent with isotopic studies...
  46. MACULAR BIOCHEMISTRY
    ALICE ADLER; Fiscal Year: 1999
    ..Focus will be placed on micronutrients, because of the possibility or preventive dietary intervention...
  47. FASEB SUMMER CONFERENCE ON MICRONUTRIENT--TRACE ELEMENTS
    Mark Failla; Fiscal Year: 1992
    This proposal requests partial funding to support the 1992 FASEB Summer Conference on Micronutrients: Trace Elements to held June 21-26, at Copper Mountain, Colorado...
  48. NUTRITION IN PREGNANCY AND INFANT HEALTH
    Graham Colditz; Fiscal Year: 2000
    ..of uncertainty regarding the effects of diet on fetal growth, especially the roles of types of fat and certain micronutrients. Even less is known about the dietary determinants of gestational length...
  49. THE EFFECT OF SMOKING CESSATION ON PLASMA MICRONUTRIENTS
    James Shikany; Fiscal Year: 2001
    High dietary intakes and blood concentrations of the micronutrients vitamin C, 13-carotene, folate, and vitamin B have been associated with a decreased risk of cardiovascular disease and/or cancer in epidemiologic studies...
  50. HUMAN BLOOD/TISSUE LEVELS/VITAMINS A, E, & CAROTENOIDS
    DAVID NIERENBERG; Fiscal Year: 1993
    ..However, blood levels of these micronutrients may be less important than tissue levels in predicting cancer chemopreventive effects...
  51. Chronic Alcohol & AIDS Impact on Muscle Wasting
    Patricia Molina; Fiscal Year: 2006
    ..In addition, chronic alcohol abuse impairs the nutritional state of the individual affecting micronutrients, which in turn, modulate circulating and tissue levels of growth factors...
  52. B-Vitamin Intake and Blood Pressure: The INTERMAP Study
    Linda Van Horn; Fiscal Year: 2003
    ..is a basic epidemiologic investigation to clarify unanswered questions on the role of macronutrients and micronutrients in the etiology of unfavorable blood pressure (BP) patterns prevailing for most middle-aged and older ..
  53. Impact of vitamin A and zinc on diarrheal disease
    KURT LONG; Fiscal Year: 2004
    ..These two micronutrients also have contrasting effects on the T helper type 1 (Th1) and type 2 (Th2) responses: vitamin A ..
  54. A TOPICAL MICRONUTRIENT DELIVERY SYSTEM
    Jaber Qasem; Fiscal Year: 2001
    ..A growing body of evidence demonstrates that micronutrients including vitamins B6, B12, C, E, folate, and niacin are involved in the maintenance of genomic integrity of ..
  55. Topical Micronutrient Delivery System
    Hyuntae Kim; Fiscal Year: 2005
    ..challenge for the development of prevention strategies for skin damage relates to the difficulty of delivering micronutrients to skin...
  56. THE RELATIONSHIP BETWEEN BLOOD AND TISSUE MICRONUTRIENT
    YEI MEI PENG; Fiscal Year: 1993
    The accumulated epidemiologic and laboratory findings have suggested that some micronutrients may inhibit or prevent the process of carcinogenesis...
  57. MICRONUTRIENTS IN IMMUNOMODULATIONS AND CANCER
    Kimberly Kline; Fiscal Year: 1992
    The long term objective of laboratory research on the role of micronutrients in immunomodulation and cancer prevention is the development of a scientifically-based dietary supplement which can be added to clinical resources for the ..
  58. ZINC AND IRON SUPPLEMENTATION: IMPACT ON DEVELOPMENT
    Maureen Black; Fiscal Year: 2002
    ..The trial had four cells: riboflavin with and without zinc, and other micronutrients [riboflavin, calcium, phosphorus, folate, and iron] with and without zinc...
  59. Mouse Models of Vitamin Transport Defects
    Judith Fleming; Fiscal Year: 2004
    ..Members of this solute carrier sub-family are 12-membrane spanning proteins that specifically transport micronutrients such as folate (SLC19A1) or thiamine (SLC19A2 and SLC19A3)...
  60. Quantification of Drusen in Macular Degeneration
    Thomas Friberg; Fiscal Year: 2003
    ..intervals to determine risk factors for AMD as well as to measure the influence of certain multivitamins and micronutrients on the progression of macular degeneration and cataract...
  61. ENVIRONMENTAL & GENETIC DETERMINANTS OF PROSTATE CANCER
    Margaret Spitz; Fiscal Year: 1999
    ..to previously reported and putative risk factors (including dietary intake of total fat, fatty acids, and micronutrients, sociodemographic factors, patterns of body fat distribution, vasectomy, family history and male patterns of ..
  62. FASEB Summer Conference on Micronutrients-Trace Elements
    Raymond Burk; Fiscal Year: 2001
    DESCRIPTION (taken from the application) The next Micronutrients: Trace Elements FASEB Summer Conference will be held June 2-7, 2001. The site of the conference will be Big Mountain Ski and Summer Resort in Whitefish, Montana...
  63. IMPACT OF MICRONUTRIENTS ON PROGRESSION OF SIV
    Sherwood Gorbach; Fiscal Year: 2004
    ..in this SIV- infected model with intramuscular Vitamin B 12 and oral selenium, the two most promising micronutrients in human studies; and 2) Conduct an HS vitamin/micronutrient intervention over 36 months in SIV-infected ..
  64. ADOLESCENT PREGNANCY: NUTRITION, GROWTH AND OUTCOME
    Theresa Scholl; Fiscal Year: 1999
    ..and maternal growth is associated with evidence of diminished placental blood flow and reduced levels of micronutrients (e.g., ferritin, folate) in cord blood...
  65. Zinc Nutrition and Brain Development in Southern Ethiopia
    K Hambidge; Fiscal Year: 2005
    ..Center and Oklahoma State University, to initiate and sustain a durable research program linking nutrition [micronutrients] and maternal-child brain development and function; [2] to complete pilot studies that will provide an ..