Bovine viral diarrhea virus 1

Summary

Alias: Pestivirus type 1, Bovine viral diarrhea virus, Mucosal disease virus, bovine viral diarrhea virus BVDV, bovine viral diarrhea virus type I, BVDV, BVDV-1, Bovine viral diarrhea virus type 1, Bovine viral diarrhea virus-1

Top Publications

  1. ncbi Maternally derived humoral immunity to bovine viral diarrhea virus (BVDV) 1a, BVDV1b, BVDV2, bovine herpesvirus-1, parainfluenza-3 virus bovine respiratory syncytial virus, Mannheimia haemolytica and Pasteurella multocida in beef calves, antibody decline
    Robert W Fulton
    Department of Veterinary Pathobiology, Oklahoma State University, College of Veterinary Medicine, Stillwater, OK 74078, USA
    Vaccine 22:643-9. 2004
  2. pmc Bovine viral diarrhea viral infections in feeder calves with respiratory disease: interactions with Pasteurella spp., parainfluenza-3 virus, and bovine respiratory syncytial virus
    R W Fulton
    Department of Infectious Diseases and Physiology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    Can J Vet Res 64:151-9. 2000
  3. ncbi Natural iminosugar derivatives of 1-deoxynojirimycin inhibit glycosylation of hepatitis viral envelope proteins
    James R Jacob
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, NY 14853, USA
    J Microbiol 45:431-40. 2007
  4. pmc Transmission of bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves
    Robert W Fulton
    Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Can J Vet Res 69:161-9. 2005
  5. ncbi Response of calves persistently infected with noncytopathic bovine viral diarrhea virus (BVDV) subtype 1b after vaccination with heterologous BVDV strains in modified live virus vaccines and Mannheimia haemolytica bacterin-toxoid
    Robert W Fulton
    Room 250, McElroy Hall, Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 21:2980-5. 2003
  6. pmc Complete genomic sequence of border disease virus, a pestivirus from sheep
    P Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, D 35392 Giessen, Germany
    J Virol 72:5165-73. 1998
  7. ncbi Genetic and antigenic characterization of novel pestivirus genotypes: implications for classification
    Paul Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, Frankfurter Strabetae 107, D 35392, Giessen, Germany
    Virology 311:96-104. 2003
  8. pmc Bovine viral diarrhea virus (BVDV) 1b: predominant BVDV subtype in calves with respiratory disease
    Robert W Fulton
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    Can J Vet Res 66:181-90. 2002
  9. ncbi Genetic diversity of pestiviruses: identification of novel groups and implications for classification
    P Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, Giessen, D 35392, Germany
    Virology 262:64-71. 1999
  10. ncbi Maternal recognition of foetal infection with bovine virus diarrhoea virus (BVDV)--the bovine pestivirus
    J Brownlie
    Department of Pathology and Infectious Diseases, Royal Veterinary College, Hatfield, Herts, UK
    Clin Diagn Virol 10:141-50. 1998

Patents

  1. Peptidomimetic Protease Inhibitors
  2. Replicons of pestiviruses that do not express c and or e1 proteinand infectious viral particles containing same, that can be used in vaccines
  3. Infectious pestivirus pseudo-particles containing functional erns, E1, E2 envelope proteins
  4. A method of detecting and/or quantifying expression of a target protein candidate in a cell, and a method of identifying a target protein of a small molecule modulator
  5. Safe mutant viral vaccines
  6. BVDV VACCINE
  7. Infectious bovine viral diarrhea virus clone
  8. Replicons of pestiviruses that do not express C and or E1 protein and infectious viral particles containing same, that can be used in
  9. Peptidomimetic Protease Inhibitors
  10. A method of detecting and/or quantifying expression of a target protein candidate in a cell, and a method of identifying a target protein of a small molecule modulator

Detail Information

Publications355 found, 100 shown here

  1. ncbi Maternally derived humoral immunity to bovine viral diarrhea virus (BVDV) 1a, BVDV1b, BVDV2, bovine herpesvirus-1, parainfluenza-3 virus bovine respiratory syncytial virus, Mannheimia haemolytica and Pasteurella multocida in beef calves, antibody decline
    Robert W Fulton
    Department of Veterinary Pathobiology, Oklahoma State University, College of Veterinary Medicine, Stillwater, OK 74078, USA
    Vaccine 22:643-9. 2004
    ..The calves were vaccinated with a commercial inactivated viral vaccine containing bovine viral diarrhea virus (BVDV)1a, BVDV2, bovine herpesvirus-1 (BHV-1), parainfluenza-3 virus (PI-3V), and bovine respiratory ..
  2. pmc Bovine viral diarrhea viral infections in feeder calves with respiratory disease: interactions with Pasteurella spp., parainfluenza-3 virus, and bovine respiratory syncytial virus
    R W Fulton
    Department of Infectious Diseases and Physiology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    Can J Vet Res 64:151-9. 2000
    The prevalence of bovine viral diarrhea virus (BVDV) infections was determined in a group of stocker calves suffering from acute respiratory disease...
  3. ncbi Natural iminosugar derivatives of 1-deoxynojirimycin inhibit glycosylation of hepatitis viral envelope proteins
    James R Jacob
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, NY 14853, USA
    J Microbiol 45:431-40. 2007
    ..activity of the silkworm extract and one of its purified constituents, 1-DNJ, was demonstrated against bovine viral diarrhea virus (BVDV) and GB virus-B (GBV-B), both members of the Flaviviridae family, and against woodchuck hepatitis ..
  4. pmc Transmission of bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves
    Robert W Fulton
    Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Can J Vet Res 69:161-9. 2005
    b>Bovine viral diarrhea virus (BVDV) persistently infected (PI) calves represent significant sources of infection to susceptible cattle...
  5. ncbi Response of calves persistently infected with noncytopathic bovine viral diarrhea virus (BVDV) subtype 1b after vaccination with heterologous BVDV strains in modified live virus vaccines and Mannheimia haemolytica bacterin-toxoid
    Robert W Fulton
    Room 250, McElroy Hall, Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA
    Vaccine 21:2980-5. 2003
    Seronegative persistently infected (PI) calves with bovine viral diarrhea virus (BVDV) subtype 1b were vaccinated with each of four modified live virus (MLV) BVDV vaccines and a Mannheimia haemolytica bacterin-toxoid...
  6. pmc Complete genomic sequence of border disease virus, a pestivirus from sheep
    P Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, D 35392 Giessen, Germany
    J Virol 72:5165-73. 1998
    The genus Pestivirus of the family Flaviviridae comprises three established species, namely, bovine viral diarrhea virus (BVDV), classical swine fever virus (CSFV), and border disease virus from sheep (BDV)...
  7. ncbi Genetic and antigenic characterization of novel pestivirus genotypes: implications for classification
    Paul Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, Frankfurter Strabetae 107, D 35392, Giessen, Germany
    Virology 311:96-104. 2003
    Currently, the genus Pestivirus comprises the four approved species Bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, Classical swine fever virus (CSFV), and Border disease virus (BDV) and one tentative fifth species represented by a ..
  8. pmc Bovine viral diarrhea virus (BVDV) 1b: predominant BVDV subtype in calves with respiratory disease
    Robert W Fulton
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA
    Can J Vet Res 66:181-90. 2002
    The prevalence of bovine viral diarrhea virus (BVDV) infections was determined in 2 groups of stocker calves with acute respiratory disease...
  9. ncbi Genetic diversity of pestiviruses: identification of novel groups and implications for classification
    P Becher
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat, Giessen, D 35392, Germany
    Virology 262:64-71. 1999
    ..Phylogenetic analysis enabled the segregation of pestiviruses into the established species bovine viral diarrhea virus-1 (BVDV-1), BVDV-2, border disease virus (BDV), and classical swine fever virus (CSFV)...
  10. ncbi Maternal recognition of foetal infection with bovine virus diarrhoea virus (BVDV)--the bovine pestivirus
    J Brownlie
    Department of Pathology and Infectious Diseases, Royal Veterinary College, Hatfield, Herts, UK
    Clin Diagn Virol 10:141-50. 1998
    ..includes classical swine fever virus (CSFV), border disease virus of sheep (BDV) and bovine virus diarrhoea virus (BVDV)...
  11. doi Rumen temperature change monitored with remote rumen temperature boluses after challenges with bovine viral diarrhea virus and Mannheimia haemolytica
    T K Rose-Dye
    Department of Animal Science, Oklahoma State University, Stillwater 74078, USA
    J Anim Sci 89:1193-200. 2011
    ..if remotely monitored rumen temperature boluses could detect a temperature change in steers exposed to bovine viral diarrhea virus (BVDV) and challenged with a common bovine respiratory disease pathogen, Mannheimia haemolytica (MH)...
  12. doi Seroprevalence and risk factors for the presence of ruminant pestiviruses in the Dutch swine population
    W L A Loeffen
    Department of Virology, Central Veterinary Institute of Wageningen UR CVI Lelystad, 8200AB Lelystad, The Netherlands
    Vet Microbiol 136:240-5. 2009
    ..infected with classical swine fever virus (CSFV), as well as ruminant pestiviruses: bovine viral diarrhoea virus (BVDV), and Border disease virus (BDV)...
  13. pmc Deletions of structural glycoprotein E2 of classical swine fever virus strain alfort/187 resolve a linear epitope of monoclonal antibody WH303 and the minimal N-terminal domain essential for binding immunoglobulin G antibodies of a pig hyperimmune serum
    M Lin
    Animal Diseases Research Institute, Nepean, Ontario, Canada
    J Virol 74:11619-25. 2000
    ..WH303) with affinity for various CSFV strains but not for the other members of the Pestivirus genus, bovine viral diarrhea virus (BVDV) and border disease virus (BDV)...
  14. pmc "Self" and "nonself" manipulation of interferon defense during persistent infection: bovine viral diarrhea virus resists alpha/beta interferon without blocking antiviral activity against unrelated viruses replicating in its host cells
    Matthias Schweizer
    Institute of Veterinary Virology, University of Bern, Laenggass Str 122, P O Box, CH 3001 Bern, Switzerland
    J Virol 80:6926-35. 2006
    b>Bovine viral diarrhea virus (BVDV), together with Classical swine fever virus (CSFV) and Border disease virus (BDV) of sheep, belongs to the genus Pestivirus of the Flaviviridae...
  15. doi Effects of exposure to calves persistently infected with bovine viral diarrhea virus type 1b and Mannheimia haemolytica challenge on animal performance, nitrogen balance, and visceral organ mass in beef steers
    L O Burciaga-Robles
    Department of Animal Science, Division of Agricultural Sciences and Natural Resources, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater 74078, USA
    J Anim Sci 88:2179-88. 2010
    ..was to determine the effects of Mannheimia haemolytica challenge after short-term exposure (72 h) to bovine viral diarrhea virus type 1b (BVDV1b) persistently infected (PI) calves on performance, N balance, and organ mass in ..
  16. doi Effect of bovine viral diarrhoea virus biotypes on adherence of sperm to oocytes during in-vitro fertilization in cattle
    M Talebkhan Garoussi
    Section of Theriogenology, Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad Iran
    Theriogenology 75:1067-75. 2011
    Bovine viral diarrhoea virus (BVDV), a member of the Pestivirus genus, is one of the most important pathogens of dairy cattle; it can cause several clinical syndromes, ranging from subclinical to severe disease...
  17. doi Associations between reproductive performance and seropositivity for bovine leukemia virus, bovine viral-diarrhea virus, Mycobacterium avium subspecies paratuberculosis, and Neospora caninum in Canadian dairy cows
    J A Vanleeuwen
    Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550, University Avenue, Charlottetown, PE, Canada
    Prev Vet Med 94:54-64. 2010
    ..was to investigate effects of seropositivity for bovine leukemia virus (BLV), Type 1 bovine viral-diarrhea virus (BVDV), Mycobacterium avium subspecies paratuberculosis (MAP), and Neospora caninum (NC), and their possible interactions,..
  18. pmc Characterization of an autonomous subgenomic pestivirus RNA replicon
    S E Behrens
    Institut für Virologie FB Veterinärmedizin, Justus Liebig Universitat Giessen, Germany
    J Virol 72:2364-72. 1998
    As an initial approach to define the requirements for the replication of bovine viral diarrhea virus (BVDV), a member of the Flaviviridae family with a positive-strand RNA genome, full-length genomic and subgenomic RNAs were originated ..
  19. ncbi Nucleotide sequence analysis of the structural gene coding region of the pestivirus border disease virus
    D G Sullivan
    Department of Pathology, Colorado State University, Fort Collins 80523
    Virus Res 33:219-28. 1994
    ..to the two other well characterized members of the Pestivirus genus of the Flaviviridae family, namely bovine viral diarrhea virus (BVDV) and hog cholera virus (HoCV)...
  20. pmc The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon
    Lorin Moes
    Evolva, CH 4123 Allschwil, Switzerland
    Virol J 4:124. 2007
    b>Bovine viral diarrhea virus (BVDV) is the prototype representative of the pestivirus genus in the Flaviviridae family...
  21. doi Humoral and T cell-mediated immune responses to bivalent killed bovine viral diarrhea virus vaccine in beef cattle
    Ratree Platt
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    Vet Immunol Immunopathol 122:8-15. 2008
    ..to evaluate the antibody and cell-mediated immune responses to a multivalent vaccine containing killed bovine viral diarrhea virus (BVDV) types 1 and 2...
  22. pmc A single point mutation in nonstructural protein NS2 of bovine viral diarrhea virus results in temperature-sensitive attenuation of viral cytopathogenicity
    Alexander Pankraz
    Department of Infectious Diseases, Institute of Virology, University of Veterinary Medicine, D 30559 Hannover, Germany
    J Virol 83:12415-23. 2009
    For Bovine viral diarrhea virus (BVDV), the type species of the genus Pestivirus in the family Flaviviridae, cytopathogenic (cp) and noncytopathogenic (ncp) viruses are distinguished according to their effect on cultured cells...
  23. ncbi Genomic analyses of bovine viral diarrhea viruses isolated from cattle imported into Japan between 1991 and 2005
    Tomoko Yamamoto
    Animal Quarantine Service, Ministry of Agriculture, Forestry and Fisheries, 11 1 Haramachi, Yokohama, Kanagawa 235 0008, Japan
    Vet Microbiol 127:386-91. 2008
    Thirty-one isolates of bovine viral diarrhea virus (BVDV) isolated within the past 15 years from imported cattle by the Japanese Animal Quarantine Service (AQS) were used in this study in which a 5'-untranslated region of each isolate ..
  24. pmc Cellular sequences in pestivirus genomes encoding gamma-aminobutyric acid (A) receptor-associated protein and Golgi-associated ATPase enhancer of 16 kilodaltons
    Paul Becher
    Institut für Virologie Fachbereich Veterinärmedizin, Justus Liebig Universitat, Frankfurter Strasse 107, D 35392 Giessen, Germany
    J Virol 76:13069-76. 2002
    ..we report the identification and characterization of two novel cellular sequences in the genomes of cp bovine viral diarrhea virus (BVDV) strains...
  25. ncbi Infectivity of bovine viral diarrhea virus associated with in vivo-derived bovine embryos
    Julie G Waldrop
    College of Veterinary Medicine, Auburn University, 100 McAdory Hall, Auburn, AL 36849 5519, USA
    Theriogenology 62:387-97. 2004
    Early research indicated that bovine viral diarrhea virus (BVDV) would not adhere to zona pellucida-intact (ZP-I), in vivo-derived bovine embryos...
  26. ncbi Experimental infection of white-tailed deer fawns (Odocoileus virginianus) with bovine viral diarrhea virus type-1 isolated from free-ranging white-tailed deer
    E A Raizman
    Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
    J Wildl Dis 45:653-60. 2009
    The objective of the current study was to elucidate the within-host dynamics of bovine viral diarrhea virus (BVDV) type-1 infection to better understand how this virus could be maintained in white-tailed deer (Odocoileus virginianus, WTD)..
  27. ncbi Evidence for persistent Bovine viral diarrhea virus infection in a captive mountain goat (Oreamnos americanus)
    Danielle D Nelson
    Washington Animal Disease Diagnostic Laboratory, College Station, Pullman, WA 99165 2037, USA
    J Vet Diagn Invest 20:752-9. 2008
    ..can produce persistently infected animals that are immunotolerant to the infecting strain of Bovine viral diarrhea virus (BVDV) and shed virus throughout their lives...
  28. ncbi Replication and persistence of different strains of bovine viral diarrhea virus in an in vitro embryo production system
    M D Givens
    Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849, USA
    Theriogenology 54:1093-107. 2000
    Recent studies have shown that exposed, in vitro-derived embryos remain contaminated with bovine viral diarrhea virus (BVDV) after washing...
  29. ncbi What is known about the antiviral agents active against bovine viral diarrhea virus (BVDV)?
    L M Finkielsztein
    Cátedra de Química Medicinal, Universidad de Buenos Aires, Argentina
    Curr Med Chem 17:2933-55. 2010
    ..This family includes three genera: Pestivirus [including bovine viral diarrhea virus (BVDV)], Flavivirus [including yellow fever virus (YFV), dengue virus, and West Nile virus (WNV)], and ..
  30. doi First report of BVDV circulation in sheep in Argentina
    S Julia
    Instituto de Virologia, Centro de Investigaciones en Ciencias Veterinarias y Agronomicas, INTA Castelar, CC 25 1712, 1686 Morón, Buenos Aires, Argentina
    Prev Vet Med 90:274-7. 2009
    ..Currently, the genus Pestivirus includes Bovine Viral Diarrhea Virus 1 (BVDV-1) and 2 (BVDV-2), Border Disease Virus (BDV), and Classical Swine Fever Virus (CSFV)...
  31. pmc Transmission of bovine viral diarrhea virus among white-tailed deer (Odocoileus virginianus)
    Thomas Passler
    College of Veterinary Medicine, JT Vaughan Large Animal Teaching Hospital, Auburn University, Auburn, AL 36849, USA
    Vet Res 41:20. 2010
    Cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV), a pestivirus in the family Flaviviridae, are an important source of viral transmission to susceptible hosts...
  32. ncbi Lymphocytopathogenic activity in vitro correlates with high virulence in vivo for BVDV type 2 strains: Criteria for a third biotype of BVDV
    Julia F Ridpath
    Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
    Virus Res 118:62-9. 2006
    Two biotypes of bovine viral diarrhea viruses (BVDV), cytopathic (cp) and noncytopathic (ncp), are recognized based on their activity in cultured epithelial cells...
  33. ncbi Failure to spread bovine virus diarrhoea virus infection from primarily infected calves despite concurrent infection with bovine coronavirus
    Rauni Niskanen
    Department of Ruminant Medicine and Veterinary Epidemiology, Swedish University of Agricultural Sciences, S 750 07 Uppsala, Sweden
    Vet J 163:251-9. 2002
    Previous reports on the spread of bovine virus diarrhoea virus (BVDV) from animals primarily infected with the agent are contradictory...
  34. pmc Suitability of vaccinia virus and bovine viral diarrhea virus (BVDV) for determining activities of three commonly-used alcohol-based hand rubs against enveloped viruses
    Gunter Kampf
    Bode Chemie GmbH and Co, KG, Scientific Affairs, Melanchthonstr, 27, 22525 Hamburg, Germany
    BMC Infect Dis 7:5. 2007
    ..and the German Association for the Control of Virus Disease (DVV) suggested that vaccinia virus and bovine viral diarrhea virus (BVDV) should be used as test viruses in a quantitative suspension test to determine the activity of a ..
  35. pmc Immunohistochemical study of Hemophilus somnus, Mycoplasma bovis, Mannheimia hemolytica, and bovine viral diarrhea virus in death losses due to myocarditis in feedlot cattle
    Deborah M Haines
    Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskathewan S7N 5B4, Canada
    Can Vet J 45:231-4. 2004
    ..study was to determine the presence of Hemophilus somnus, Mycoplasma bovis, Mannheimia hemolytica, and bovine viral diarrhea virus (BVDV) in lesional tissues of feeder calves dying with myocarditis...
  36. ncbi Further characterization of border disease virus isolates: evidence for the presence of more than three species within the genus pestivirus
    P Becher
    Federal Research Centre for Virus Diseases of Animals, Tubingen, Germany
    Virology 209:200-6. 1995
    ..two distinct groups of sheep-derived pestiviruses, namely "true" border disease virus strains (BDV) and bovine viral diarrhea virus (BVDV)-like strains...
  37. doi Seroconversion to bovine viral diarrhoea virus and infectious bovine rhinotracheitis virus in dairy herds of Michoacan, Mexico
    Jose C Segura-Correa
    Facultad de Medicina Veterinaria y Zootecnia, UADY, Km 15 5 carretera Mérida Xmatkuil, A P 4 116, Itzimná, Merida, Yucatan, Mexico
    Trop Anim Health Prod 42:233-8. 2010
    Bovine viral diarrhoea virus (BVDV) and infectious bovine rhinotracheitis virus (IBRV) are important viral diseases around the world...
  38. doi Risk factors associated with Neospora caninum seropositivity in randomly sampled Canadian dairy cows and herds
    J A Vanleeuwen
    Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown, PE, Canada C1A 4P3
    Prev Vet Med 93:129-38. 2010
    ..controlling for important confounding variables and co-infections with bovine leukemia virus (BLV), bovine viral diarrhea virus (BVDV) and Mycobacterium avium subspecies paratuberculosis (MAP)...
  39. doi Molecular characterization of bovine viral diarrhea virus type 2 isolate originating from a native Indian sheep (Ovies aries)
    N Mishra
    High Security Animal Disease Laboratory, Indian Veterinary Research Institute, Anand Nagar, Bhopal 462021, Madhya Pradesh, India
    Vet Microbiol 130:88-98. 2008
    The wide spread prevalence of bovine viral diarrhea virus type 1 (BVDV-1) in cattle and recent identification of BVDV-2 in goats in India warranted pestivirus surveillance in sheep...
  40. ncbi Viral antigen distribution in the respiratory tract of cattle persistently infected with bovine viral diarrhea virus subtype 2a
    A W Confer
    Department of Veterinary Pathobiology and the Oklahoma Animal Disease Diagnostic Laboratory, 211 McElroy Hall, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Vet Pathol 42:192-9. 2005
    ..bifurcation, and lung from each of 10 clinically healthy calves persistently infected (PI) with bovine viral diarrhea virus (BVDV) serotype 2a...
  41. doi Serological response of guinea pigs to oily and aqueous inactivated vaccines containing a Brazilian isolate of the Bovine Viral Diarrhea Virus (BVDV)
    Ricardo Spacagna Jordão
    Laboratório de Produção de Imunobiológicos, Instituto Biologico, Av Cons Rodrigues Alves 1252, 04014 002 São Paulo, Brazil
    Res Vet Sci 91:311-5. 2011
    b>Bovine Viral Diarrhea Virus (BVDV) is widespread in cattle in Brazil and research shows its large antigenic variability. Available vaccines are produced with virus strains isolated in other countries and may not be effective...
  42. pmc Seroepidemiology of bovine viral diarrhoea virus (BVDV) in the Adamawa Region of Cameroon and use of the SPOT test to identify herds with PI calves
    Ian G Handel
    The Roslin Institute at the Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom
    PLoS ONE 6:e21620. 2011
    Bovine viral diarrhoea, caused by the bovine viral diarrhoea virus (BVDV) in the Pestivirus genus of the Flaviviridae, is one of the most important diseases of cattle world wide causing poor reproductive performance in adult cattle and ..
  43. pmc Noncytopathic bovine viral diarrhea virus inhibits double-stranded RNA-induced apoptosis and interferon synthesis
    M Schweizer
    Institute of Veterinary Virology, University of Bern, CH 3012 Bern, Switzerland
    J Virol 75:4692-8. 2001
    b>Bovine viral diarrhea virus (BVDV), a pestivirus of the Flaviviridae family, is an economically important cattle pathogen with a worldwide distribution...
  44. ncbi Antiviral activity of hop constituents against a series of DNA and RNA viruses
    Victor E Buckwold
    Infectious Disease Research Department, Southern Research Institute, 431 Aviation Way, Frederick, MD 21701, USA
    Antiviral Res 61:57-62. 2004
    ..These hop constituents were tested for antiviral activity against bovine viral diarrhea virus (BVDV) as a surrogate model of hepatitis C virus (HCV), human immunodeficiency virus (HIV), influenza A ..
  45. pmc Cytopathic bovine viral diarrhea viruses (BVDV): emerging pestiviruses doomed to extinction
    Ernst Peterhans
    Institute of Veterinary Virology, University of Bern, Bern, Switzerland
    Vet Res 41:44. 2010
    b>Bovine viral diarrhea virus (BVDV), a Flaviviridae pestivirus, is arguably one of the most widespread cattle pathogens worldwide. Each of its two genotypes has two biotypes, non-cytopathic (ncp) and cytopathic (cp)...
  46. doi Protection from persistent infection with a bovine viral diarrhea virus (BVDV) type 1b strain by a modified-live vaccine containing BVDV types 1a and 2, infectious bovine rhinotracheitis virus, parainfluenza 3 virus and bovine respiratory syncytial virus
    Wenzhi Xue
    Intervet Schering Plough Animal Health, 35500W 91st Street, De Soto, KS 66018, USA
    Vaccine 29:4657-62. 2011
    Recent studies showed that BVDV-1b subgenotype is dominant in North and South American field BVDV isolates. However, nearly all commercially available BVDV-1 vaccines contain BVDV-1a strains...
  47. ncbi Ruminant pestivirus infection in pigs
    B Liess
    Institute of Virology, Division of Clinical Virology, Hanover Veterinary School, Federal Republic of Germany
    Rev Sci Tech 9:151-61. 1990
    ..iii) degree of homology of virus strains used for serology, with field strains of bovine virus diarrhoea virus (BVDV) infecting pigs. Emphasis should be laid on sources of BVDV other than cattle, e.g...
  48. ncbi Production and characterization of monoclonal antibodies to Brazilian isolates of bovine viral diarrhea virus
    L C Kreutz
    Laboratorio de Virologia, Departamento de Medicina Veterinaria Preventiva, Microbiologia e Parasitologia, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil
    Braz J Med Biol Res 33:1459-66. 2000
    Three Brazilian isolates of bovine viral diarrhea virus (BVDV), antigenically distinct from the standard North American isolates, were selected to immunize BALB/c mice in order to obtain hybridoma cells secreting anti-BVDV monoclonal ..
  49. doi Genetic diversity of pestivirus isolates in cattle from Western Austria
    Andrea Hornberg
    Austrian Agency for Health and Food Safety AGES, Robert Koch Gasse 17, 2340 Moedling, Austria
    Vet Microbiol 135:205-13. 2009
    The genetic diversity of bovine viral diarrhoea virus (BVDV) isolates in infected cattle from Tyrol and Vorarlberg (Austria) was investigated...
  50. ncbi [Kinetics and persistence of neutralizing antibodies against bovine viral diarrhea virus-1 and -2 and border disease virus after two step vaccination of cattle]
    T C Oguzoglu
    Institut fur Virologie, Tierarztliche Hochschule Hannover
    Dtsch Tierarztl Wochenschr 110:14-7. 2003
    The aim of the study was the assessment of rise and persistence of neutralizing antibodies (nAb) to bovine viral diarrhea virus (BVDV) and border disease virus (BDV) after a two step vaccination using an inactivated BVDV/BDV (Mucobovin) ..
  51. ncbi Clinical and epidemiologic observations of bovine viral diarrhea virus in the northwestern United States
    James F Evermann
    Washington Animal Disease Diagnostic Laboratory, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA
    Vet Microbiol 89:129-39. 2002
    Retrospective analyses of cases from which bovine viral diarrhea virus (BVDV) was isolated from 1980 to 2000 were conducted. These cases originated from the northwestern US and included both beef and dairy cattle...
  52. ncbi Genetic variety of bovine viral diarrhea virus 2 strains isolated from sheep
    Massimo Giangaspero
    Institute of Special Pathology and Veterinary Medical Clinic, The University of Milan, Italy
    J Vet Med Sci 66:323-6. 2004
    b>Bovine viral diarrhea virus 2 (BVDV-2) strains, isolated from sheep showing clinical symptoms of border disease, have been evaluated by the palindromic nucleotide substitution (PNS) method at the three variable loci (V1, V2 and V3) in ..
  53. doi Development and validation of an ELISA for quantitation of bovine viral diarrhea virus antigen in the critical stages of vaccine production
    A Pecora
    Instituto de Virologia, CICVyA, INTA Castelar, 1686 Buenos Aires, Argentina
    J Virol Methods 162:170-8. 2009
    b>Bovine Viral Diarrhea Virus (BVDV) is the causative agent of a worldwide disease. The virus infects bovines of all ages, causing reproductive problems and contaminating biological products of high commercial value...
  54. ncbi A scoring system for risk assessment of the introduction and spread of bovine viral diarrhoea virus in dairy herds in Northern Italy
    Camilla Luzzago
    Universita degli Studi di Milano, Dipartimento Patologia Animale, Igiene e Sanita Pubblica Veterinaria, Milano, Italy
    Vet J 177:236-41. 2008
    ..this study aimed to develop an integrated scoring system for the risk assessment of bovine viral diarrhoea virus (BVDV) infection in dairy herds in Northern Italy...
  55. ncbi Foetal cross-protection experiments between type 1 and type 2 bovine viral diarrhoea virus in pregnant ewes
    D J Paton
    Central Veterinary Laboratory, Veterinary Laboratories Agency, Surrey, UK
    Vet Microbiol 64:185-96. 1999
    ..and given an intranasal dose of either cell culture medium, or a type 1 or a type 2 bovine viral diarrhoea virus (BVDV-1 or BVDV-2)...
  56. ncbi Clinical response and immunomodulation following experimental challenge of calves with type 2 noncytopathogenic bovine viral diarrhea virus
    D Archambault
    Departement des Sciences Biologiques, Universite du Quebec a Montreal, Canada
    Vet Res 31:215-27. 2000
    Eight calves between 16 and 18 weeks of age that were seronegative to bovine viral diarrhea virus (BVDV), bovine leucosis virus and bovine immunodeficiency-like virus were infected (day 0) intranasally with the type 2 noncytopathogenic ..
  57. doi Impact of oral meloxicam and long-distance transport on cell-mediated and humoral immune responses in feedlot steers receiving modified live BVDV booster vaccination on arrival
    N K Van Engen
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, 50011, USA
    Vet Immunol Immunopathol 175:42-50. 2016
    ..on arrival (day 0) and after 7days, and that CMI following vaccination with a modified live bovine viral diarrhea virus (BVDV) recall antigen would be increased...
  58. pmc Persistent infections after natural transmission of bovine viral diarrhoea virus from cattle to goats and among goats
    Claudia Bachofen
    Institute of Veterinary Virology, University of Bern, Länggassstr, 122, P, O, Box 8466, CH 3001 Bern, Switzerland
    Vet Res 44:32. 2013
    Bovine viral diarrhoea virus (BVDV) is an economically important pathogen of cattle worldwide...
  59. pmc Identification of a cell population that produces alpha/beta interferon in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus
    L S Brackenbury
    Institute for Animal Health, Compton, Newbury, Berkshire RG20 7NN, United Kingdom
    J Virol 79:7738-44. 2005
    In vitro infection of bovine cells of many origins with the cytopathogenic bovine viral diarrhea virus (cpBVDV) results in the induction of alpha/beta interferon (IFN-alpha/beta), whereas noncytopathogenic BVDV (ncpBVDV) isolates have ..
  60. ncbi Serological status for N. caninum, bovine viral diarrhea virus, and infectious bovine rhinotracheitis virus at pregnancy testing and reproductive performance in beef herds
    C L Waldner
    Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, 52 Campus Drive, University of Saskatchewan, Saskatoon, Sask, Canada
    Anim Reprod Sci 90:219-42. 2005
    Neospora caninum, infectious bovine rhinotracheitis (IBR), and bovine viral diarrhea virus (BVDV) are important differentials for the diagnosis of infectious reproductive loss in beef herds...
  61. pmc The effect of bovine viral diarrhea virus (BVDV) strains on bovine monocyte-derived dendritic cells (Mo-DC) phenotype and capacity to produce BVDV
    Mrigendra K S Rajput
    Department of Veterinary and Biomedical Sciences, SDSU, Brookings, SD 57007, USA
    Virol J 11:44. 2014
    ..In this study, the ability of bovine viral diarrhea virus (BVDV) to replicate and produce infectious virus in monocyte-derived dendritic cells (Mo-DC) and ..
  62. ncbi Assessing the effect of sample handling on the performance of a commercial bovine viral diarrhea virus antigen-capture enzyme-linked immunosorbent assay
    Matthew C Reed
    College of Veterinary Medicine, Iowa State University, Ames, IA 50010, USA
    J Vet Diagn Invest 20:124-6. 2008
    ..In this study, as part of the Voluntary Iowa Bovine Viral Diarrhea Virus Screening Project held in 2006, 2 sample-handling practices were evaluated to determine how they affect ..
  63. doi High prevalence of bovine viral diarrhea virus 1 in Chinese swine herds
    Yu Deng
    Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
    Vet Microbiol 159:490-3. 2012
    Nested RT-PCR was used to investigate bovine viral diarrhea virus in 511 specimens collected from Chinese pigs exhibiting clinical symptoms between 2007 and 2010...
  64. doi Influence of herd structure and type of virus introduction on the spread of bovine viral diarrhoea virus (BVDV) within a dairy herd
    Pauline Ezanno
    INRA, UMR1300, Bio agression, Epidémiologie et Analyse de Risques, BP 40706, 44307 Nantes, France
    Vet Res 39:39. 2008
    ..Herd structure varies among cattle herds. However, published models of the spread of bovine viral diarrhoea virus (BVDV) assume no herd structure or a unique structure chosen as a representative...
  65. ncbi Isolation of BVDV from bovine serum by EMEA/CVMP and 9 CFR: a comparison
    J W Black
    American BioResearch Laboratory, Sevierville, TN 37964, USA
    Dev Biol (Basel) 126:293-9; discussion 327. 2006
    Data derived from both experience and validation exercises on the behaviour and properties of BVDV is presented as applied to recovery of the virus from bovine serum used in the industrial production of animal biologicals...
  66. doi Occurrence of antibodies anti -Toxoplasma gondii, Neospora caninum and Leptospira interrogans in a captive deer herd in Southern Brazil
    Cristina Kraemer Zimpel
    Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    Rev Bras Parasitol Vet 24:482-7. 2015
    ..were tested for Brucella abortus, Leptospira (23 serovars), Toxoplasma gondii, Neospora caninum, bovine viral diarrhea virus, infectious bovine rhinotracheitis virus, foot-and-mouth disease virus, western equine encephalitis ..
  67. doi Biosecurity aspects and pathogen inactivation in acidified high risk animal by-products
    Björn Vinnerås
    Department of Chemistry, Environment and Feed Hygiene, National Veterinary Institute, Uppsala, Sweden
    J Environ Sci Health A Tox Hazard Subst Environ Eng 47:1166-72. 2012
    ..of Salmonella Typhimurium, Bacillus cereus spores, porcine herpes virus, avian influenza virus, bovine viral diarrhea virus, equine rhinitis A virus and porcine parvovirus in Biomal at different storage times...
  68. doi Identification and characterization of mimotopes of classical swine fever virus E2 glycoprotein using specific anti-E2 monoclonal antibodies
    Melissa Batonick
    USDA, APHIS, Veterinary Services, National Veterinary Services Laboratories, Foreign Animal Disease Diagnostic Laboratory, United States
    Virus Res 175:12-9. 2013
    ..nucleic acid and amino acid sequence homology with the other members of the pestivirus genus, namely bovine viral diarrhea virus and border disease virus...
  69. doi Herpetiform genital lesions in a heifer with mucosal disease
    J J Fabis
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Vet Pathol 45:212-6. 2008
    ..Lesions of the vulva similar to those seen in some stages of infectious pustular vulvovaginitis were negative for bovine herpesvirus-1 and tested positive for bovine viral diarrhea virus antigen by immunohistochemistry.
  70. ncbi Pestivirus exposure in free-living and captive deer in Austria
    Reinhild Krametter
    II Medical Clinic for Ruminants and Swine, Veterinary University of Vienna, 1210 Vienna, Austria
    J Wildl Dis 40:791-5. 2004
    ..Sera were tested for antibodies against bovine viral diarrhea virus (BVDV) with an enzyme-linked immunosorbent assay (ELISA) and virus neutralization tests against three ..
  71. pmc Pestivirus virion morphogenesis in the absence of uncleaved nonstructural protein 2-3
    E Lattwein
    Institute for Virology and Cell Biology, University of Lubeck, Ratzeburger Allee 160, D 23562 Lubeck, Germany
    J Virol 86:427-37. 2012
    ..g., hepatitis C virus [HCV]), and Pestivirus. Pestiviruses, like bovine viral diarrhea virus (BVDV), bear a striking degree of similarity to HCV concerning polyprotein organization, processing, ..
  72. doi The effects of viral vaccination of dairy heifer calves on the incidence of respiratory disease, mortality, and growth
    M C Windeyer
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
    J Dairy Sci 95:6731-9. 2012
    ..Calves were randomly assigned to receive a commercial, intramuscular, modified-live vaccine against bovine viral diarrhea virus types 1 and 2, bovine respiratory syncytial virus, bovine herpesvirus type 1, and parainfluenza virus ..
  73. ncbi Mapping of two antigenic domains on the NS3 protein of the pestivirus bovine viral diarrhea virus
    Dirk Deregt
    Lethbridge Laboratory Animal Diseases Research Institute, Canadian Food Inspection Agency, P O Box 640, Lethbridge, Alta, Canada T1J 3Z4
    Vet Microbiol 108:13-22. 2005
    The immunodominant NS3 (p80) protein of the pestivirus bovine viral diarrhea virus (BVDV) functions as a serine protease and a RNA helicase...
  74. doi Virucidal activity of ortho-phthalaldehyde solutions against hepatitis B and C viruses
    Charles G Roberts
    Advanced Sterilization Products, Johnson and Johnson Company, Irvine, CA 92618, USA
    Am J Infect Control 36:223-6. 2008
    ..The surrogate viruses, duck hepatitis B virus (DHBV) and bovine viral diarrhea virus (BVDV), were used to assess the virucidal efficacy of OPA on HBV and HCV, respectively...
  75. pmc Epidemiology and genetic characterization of BVDV, BHV-1, BHV-4, BHV-5 and Brucella spp. infections in cattle in Turkey
    Muhammet Eren Aslan
    Department of Virology, Faculty of Veterinary Medicine, Kirikkale University, Kirikkale 71450, Turkey
    J Vet Med Sci 77:1371-7. 2015
    The aim of the study was to determine the epidemiological data of bovine viral diarrhea virus (BVDV), bovine herpesvirus-1 (BHV-1), bovine herpesvirus-4 (BHV-4), bovine herpesvirus-5 (BHV-5) and Brucella-associated cattle that were ..
  76. doi Two newly developed E(rns)-based ELISAs allow the differentiation of Classical Swine Fever virus-infected from marker-vaccinated animals and the discrimination of pestivirus antibodies
    Andrea Aebischer
    Institute of Virology and Immunoprophylaxis, Sensemattstrasse 293, CH 3147 Mittelhäusern, Switzerland
    Vet Microbiol 161:274-85. 2013
    ..the most promising live marker vaccine candidate currently available, is a genetically modified Bovine Viral Diarrhea virus expressing the E2 glycoprotein of CSFV strain Alfort/187...
  77. doi Development of fetal and placental innate immune responses during establishment of persistent infection with bovine viral diarrhea virus
    Natalia P Smirnova
    Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 1683 Campus Delivery, Fort Collins, CO 80523 1683, USA
    Virus Res 167:329-36. 2012
    ..b>Bovine viral diarrhea virus (BVDV) has the ability to cross the placenta and infect the fetus...
  78. ncbi Experimental superinfection of a Lesser Malayan mousedeer (Tragulus javanicus) persistently infected with bovine viral diarrhea virus
    Antje Semrau
    Leibniz Institute for Zoo and Wildlife Research, Alfred Kowalke Strasse 17, 10315 Berlin, Germany
    J Zoo Wildl Med 39:124-7. 2008
    A Lesser Malayan mousedeer (Tragulus javanicus), persistently infected with noncytopathogenic bovine viral diarrhea virus (BVDV) type 1f, was experimentally superinfected with a cytopathogenic isolate of BVDV type 1c, which antigenically ..
  79. doi Serologic, trace element, and fecal parasite survey of free-ranging, female mule deer (Odocoileus hemionus) in eastern Washington, USA
    Woodrow L Myers
    1 Washington Department of Fish and Wildlife, 2315 N Discovery Place, Spokane Valley, Washington 99216, USA
    J Wildl Dis 51:125-36. 2015
    ..Leptospira interrogans serovar Canicola (1%), Leptospira interrogans serovar Grippotyphosa (13%), Bovine viral diarrhea virus 1 (57%), Bovine respiratory syncytial virus (71%), Infectious bovine rhinotracheitis virus (51%), Bovine ..
  80. doi Effect of injectable trace minerals on the humoral immune response to multivalent vaccine administration in beef calves
    J D Arthington
    Institute of Food and Agricultural Sciences, University of Florida, FL, USA edu
    J Anim Sci 90:1966-71. 2012
    ..2 kg), seronegative for bovine herpesvirus-1 (BHV-1) and bovine viral diarrhea virus, genotypes 1 and 2 (BVDV-1 and BVDV-2), were sourced from 2 locations...
  81. pmc Genome Sequence of a Subgenotype 1a Bovine Viral Diarrhea Virus in China
    Shandian Gao
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping, Lanzhou, Gansu, People s Republic of China
    Genome Announc 4:. 2016
    A bovine viral diarrhea virus (BVDV), GS5, of the BVDV-1a subgenotype was isolated from dairy cattle in Gansu Province, northwest China...
  82. doi Milk as a diagnostic sample for a commercially available ELISA to identify bovine viral diarrhoea (BVD) antibodies in dairy herds
    S R Lanyon
    School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, 5371, Australia
    Aust Vet J 92:269-73. 2014
    ..of this study were to evaluate a commercially available ELISA for the detection of bovine viral diarrhoea virus (BVDV)-specific antibodies in individual milk compared with individual serum samples, and in bulk milk samples compared ..
  83. pmc Detection and identification of the atypical bovine pestiviruses in commercial foetal bovine serum batches
    Hongyan Xia
    Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden
    PLoS ONE 6:e28553. 2011
    ..According to the certificate of analysis that the suppliers claimed for each batch of FBS, BVDV-1 was detected in all 11 countries and BVDV-2 was detected exclusively in the America Continent...
  84. doi Simulation of the K-function in the analysis of spatial clustering for non-randomly distributed locations--exemplified by bovine virus diarrhoea virus (BVDV) infection in Denmark
    A K Ersbøll
    Department of Large Animal Sciences, Faculty of Life Sciences, University of Copenhagen, Frederiksberg C, Denmark
    Prev Vet Med 91:64-71. 2009
    ..The approach also overcomes edge effects and problems with complex shapes of the study region. An application to bovine virus diarrhoea virus (BVDV) infection in Denmark is described.
  85. doi Yeast-surface expressed BVDV E2 protein induces a Th1/Th2 response in naïve T cells
    Robert Patterson
    Royal Veterinary College, Department of Pathology and Infectious Diseases, Hawkshead Lane, Hatfield AL9 7TA, UK
    Dev Comp Immunol 37:107-14. 2012
    ..In the current project, we express the immunogenic envelope protein E2 of bovine viral diarrhoea virus (BVDV) on the surface of S. cerevisiae...
  86. doi Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents
    Michele Tonelli
    Dipartimento di Farmacia, Universita di Genova, Viale Benedetto XV 3, 16132 Genova, Italy Electronic address
    Bioorg Med Chem 22:4893-909. 2014
    ..Fifty-two of them displayed different levels of activity against one or more viruses, among which CVB-5, RSV, BVDV and Sb-1 were the most frequently affected...
  87. doi Molecular diversity of bovine viral diarrhea virus in uruguay
    L Maya
    Laboratorio de Virologia Molecular, Regional Norte, CENUR Noroeste, Universidad de la Republica, Gral Rivera 1350, 50000, Salto, Uruguay
    Arch Virol 161:529-35. 2016
    ..Two viral species has been recognized: BVDV-1 and BVDV-2, both distributed worldwide. Recently, novel specie of BVDV named HoBi-like pestivirus was discovered...
  88. doi A serosurvey for ruminant pestivirus exposure conducted using cattle sera collected for brucellosis surveillance in the United States
    Fernando V Bauermann
    National Animal Disease Center, Agricultural Research Services, Ames, IA Bauermann, Ridpath
    J Vet Diagn Invest 29:76-82. 2017
    Four species of ruminant pestivirus are currently circulating in the United States: Bovine viral diarrhea virus 1 and 2 (BVDV-1, -2; predominant host: cattle), Border disease virus (BDV; predominant host: sheep), and pronghorn virus (..
  89. ncbi Molecular epidemiology of bovine viral diarrhoea during the final phase of the Swedish BVD-eradication programme
    Karl Ståhl
    Department of Biomedical Sciences and Veterinary Public Health, SLU, Box 7036, S 750 07 Uppsala, Sweden
    Prev Vet Med 72:103-8; discussion 215-9. 2005
    ..the first results of a programme where we apply a molecular-epidemiological approach to trace sources and routes of BVDV infection, and that we expect will speed up the final phase of the BVD-programme and help to reach total eradication...
  90. doi Development of a RT-PCR ELISA for simultaneous detection of BVDV-1, BVDV-2 and BDV in ruminants and its evaluation on clinical samples
    Pooja Dubey
    National Institute of High Security Animal Diseases formerly HSADL, Indian Council of Agricultural Research, Anand Nagar, Bhopal, Madhya Pradesh 462021, India
    J Virol Methods 213:50-6. 2015
    ..When the assay was evaluated on the samples obtained from animals infected experimentally with BVDV and from the field using virus isolation as standard, it showed a high diagnostic sensitivity (95...
  91. doi Distribution of lymphoid depletion and viral antigen in alpacas experimentally infected with Bovine viral diarrhea virus 1
    David J Steffen
    1David Steffen, Veterinary Diagnostic Center, Fair Street and Campus Loop, University of Nebraska, Lincoln, NE 68583 0907
    J Vet Diagn Invest 26:35-41. 2014
    It was hypothesized that acute postnatal Bovine viral diarrhea virus 1 (BVDV-1) infection leads to leukopenia and lymphoid depletion of gut-associated lymphoid tissues similar to acute disease in calves...
  92. doi Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor
    Giuseppe Manfroni
    Dipartimento di Chimica e Tecnologia del Farmaco, Universita degli Studi di Perugia, Via del Liceo, 1, 06123 Perugia, Italy
    J Med Chem 52:3354-65. 2009
    ..C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral diarrhea virus (BVDV) compound...
  93. doi Molecular mechanism of viral resistance to a potent non-nucleoside inhibitor unveiled by molecular simulations
    Shailendra Asthana
    Dipartimento di Fisica, Universita degli Studi di Cagliari, Cittadella Universitaria, 09042 Monserrato, CA, Italy
    Biochemistry 53:6941-53. 2014
    Recently, we reported on a potent benzimidazole derivative (227G) that inhibits the growth of the bovine viral diarrhea virus (BVDV) in cell-based and enzyme assays at nanomolar concentrations...
  94. ncbi Respiratory disease associated with bovine coronavirus infection in cattle herds in Southern Italy
    Nicola Decaro
    Department of Animal Health and Well Being, Faculty of Veterinary Medicine of Bari, s p per Casamassima km 3, 70010 Valenzano, Bari, Italy
    J Vet Diagn Invest 20:28-32. 2008
    ..e., bovine respiratory syncytial virus, bovine herpesvirus type 1, bovine viral diarrhea virus, bovine parainfluenza virus)...
  95. pmc Comparison of bulk milk antibody and youngstock serology screens for determining herd status for Bovine Viral Diarrhoea Virus
    Richard E Booth
    Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, UK
    BMC Vet Res 12:177. 2016
    ..for determining the presence or absence of animals persistently infected (PI) with Bovine Viral Diarrhoea Virus (BVDV) within a herd...
  96. ncbi Acute non-cytopathic bovine viral diarrhea virus infection induces pronounced type I interferon response in pregnant cows and fetuses
    Natalia P Smirnova
    Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1683, USA
    Virus Res 132:49-58. 2008
    b>Bovine viral diarrhea virus (BVDV) infection occurs in the cattle population worldwide. Non-cytopathic (ncp) BVDV strains cause transient infection (TI) or persistent infection (PI) depending on the host's immune status...
  97. doi Study of the kinetics of antibodies titres against viral pathogens and detection of rotavirus and parainfluenza 3 infections in captive crias of guanacos (Lama guanicoe)
    G Marcoppido
    Instituto de Virologia, CICVyA, INTA Castelar, Buenos Aires, Argentina
    Transbound Emerg Dis 58:37-43. 2011
    ..Ab) to Rotavirus (RV), Parainfluenza-3 virus (PI-3), Bovine Herpesvirus-1 (BoHV-1), Bovine Viral Diarrhoea virus (BVDV-1) and Bluetongue virus (BTV) in eleven guanaco's crias (chulengos) relocated from Rio Negro to Buenos Aires ..
  98. doi Herd-level factors associated with the presence of bovine viral diarrhoea virus in herds participating in the voluntary phase of the Irish national eradication programme
    D A Graham
    Animal Health Ireland, Main Street, Carrick on Shannon, Leitrim, Ireland
    Prev Vet Med 112:99-108. 2013
    ..to identify variables associated with initial positive or inconclusive results for bovine viral diarrhoea virus (BVDV) in ear punch samples collected from calves between 1st January and 15th July 2012 (the study period) as part of ..
  99. ncbi Interferon-gamma and interleukin-4 mRNA expression by peripheral blood mononuclear cells from pregnant and non-pregnant cattle seropositive for bovine viral diarrhea virus
    A S Waldvogel
    Institute of Veterinary Pathology, University of Berne, Langgass strasse 122, CH 3012, Berne, Switzerland
    Vet Immunol Immunopathol 77:201-12. 2000
    ..was to examine cytokine expression in peripheral blood mononuclear cells (PBMCs) from cattle immune to bovine viral diarrhea virus (BVDV) to determine whether pregnancy also has an influence on the type of immune response in this ..
  100. doi Antibody titers to vaccination are not predictive of level of protection against a BVDV type 1b challenge in Bos indicus - Bos taurus steers
    E D Downey-Slinker
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, TX 77843, USA Electronic address
    Vaccine 34:5053-9. 2016
    ..MLV) vaccine, or no vaccine (control), and were challenged with a noncytopathic 1b field strain of bovine viral diarrhea virus. Rectal temperature and levels of circulating lymphocytes and platelets were monitored following ..
  101. ncbi Apoptosis inhibitors delay the cytopathic effect of bovine viral diarrhoea virus (BVDV)
    B Grummer
    Institute of Virology, School of Veterinary Medicine, Hannover, Germany
    J Vet Med B Infect Dis Vet Public Health 49:298-303. 2002
    Based on their action in cell culture, two biotypes of bovine viral diarrhoea virus (BVDV) can be distinguished. The noncytopathic (ncp) BVDV isolated from persistently infected animals cause no visible damage to cultured bovine cells...

Research Grants31

  1. Identification and Analysis of Flavivirus Protease and RNA Helicase Inhibitors
    Radhakrishnan Padmanabhan; Fiscal Year: 2009
    ..recently reported crystal structures of YFV and DEN2 RNA helicases and those of hepatitis C virus and bovine viral diarrhea virus (BVDV) RdRP for docking studies...
  2. Imino sugars for flavivirus infections of bioterror
    Timothy M Block; Fiscal Year: 2010
    ..These will first be tested for the ability to inhibit bovine viral diarrhea (BVDV) in yield reduction assays, since it shares the same step as other flaviviruses in the virus life cycle that is ..
  3. Novel agents against West Nile Virus infections
    Krzysztof Pankiewicz; Fiscal Year: 2003
    ..and mycophenolic adenine dinucleotide (MAD) analogues showed activity against closely related Bovine Viral Diarrhea virus, novel compounds such as phosphonate analogues of MPA and analogues of mycophenolic adenine ..
  4. Antiviral agents for Flavivirus infections of bioterror
    Timothy Block; Fiscal Year: 2003
    ..potential are difficult or dangerous to grow in tissue culture, but the flavivirus family member bovine viral diarrhea virus (BVDV) is easily quantified in tissue culture, we have been using BVDV as a surrogate...
  5. Development of Novel Hepatits C Virus Inhibitors
    TODD PARSLEY; Fiscal Year: 2009
    ..therapeutic index than the approved therapeutic ribavirin in in vitro assays using the HCV surrogate bovine viral diarrhea virus (BVDV)...
  6. Effect of Thiopurines on RNA Viruses/Hepatitis C Virus
    Robert Striker; Fiscal Year: 2005
    ..We have determined conditions in which thiopurine nucleoside analogs inhibit a model Flaviviridae, Bovine Viral Diarrhea Virus (BVDV), in cell culture without cytotoxicity...
  7. CRYOBARIC VIRAL INACTIVATION FOR IMMUNOGLOBULIN
    Feng Tao; Fiscal Year: 2000
    ..In the proposed research, we will add human immunodeficiency virus (HIV-1), bovine viral diarrhea virus (BVDV, a surrogate for hepatitis C virus), duck hepatitis B virus (a surrogate for human hepatitis B ..
  8. MUTATION 'REFRACTION' BROAD SPECTRUM ANTI-HEPATITIS DRUG
    Timothy Block; Fiscal Year: 2000
    ..Studies to examine the frequency of spontaneously occurring glucosidase inhibitor mutants of bovine viral diarrhea virus, which will be used as a tissue culture model for HCV will also be performed...
  9. ANTI-VIRAL TREATMENT OF DEVELOPING BOVINE EMBRYOS
    Maurice Givens; Fiscal Year: 2002
    ..produced bovine embryos are potential vectors for transmission of the ruminant pestivirus known as bovine viral diarrhea virus (BVDV)...
  10. Novel Class of Compounds for Treatment of HCV Infections
    Krzysztof Pankiewicz; Fiscal Year: 2003
    ..During the course of our search for nucleosides that may inhibit replication of bovine viral diarrhea virus (BVDV), used as an HCV surrogate, we discovered potent inhibitory activity of 3-beta-D-ribofuranosyl-9,..
  11. Identification of novel antiviral targets using RNAi
    CATHERINE PACHUK; Fiscal Year: 2002
    ..system, a DNA containing virus, human herpes simplex virus type I (HSV-1), and an RNA containing virus, bovine viral diarrhea virus (BVDV). BVDV is a tissue culture surrogate for hepatitis C virus...
  12. HCV Nonstructural Proteins and Host Protein Secretion
    Kouacou Konan; Fiscal Year: 2006
    ..Similar studies will be done with homologous proteins of BVDV, a flavivirus that can be conveniently and safely be grown in tissue culture...
  13. Modified nucleosides for Hepatitis C Virus
    Lieven Stuyver; Fiscal Year: 2002
    ..Phase 2 will include advanced toxicological and early human studies. ..
  14. SELECTIVE INHIBITION OF HCV TRANSLATION BY TETRAPEPTIDE
    ALEXANDER BIRK; Fiscal Year: 2008
    ..If DAPL or related analogues can be further developed to target and inhibit HCV RNA translation, the clinical application of this kind of therapeutics might be significant. ..
  15. Nanoarray-Type Detection of Oct3/4 and Cdx2 using AuNPs and E-beam Patterns
    Jeong Yeol Yoon; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Conference--Drug development for Viral Hepatitis
    Charles Rice; Fiscal Year: 2005
    ..Support is requested to help defray the publications costs of the abstract book and for equipment used to facilitate delivery and display of the oral and poster presentations...
  17. HEPATITIS C VIRUS IN ETIOLOGY OF WA RHEUMATOID FACTORS
    Vincent Agnello; Fiscal Year: 2001
    ..abstract_text> ..
  18. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  19. Development of Inhibitors Against HCV Infection
    Joshua Ojwang; Fiscal Year: 2002
    ..To overcome this difficulty, surrogate animal viruses are being used, including bovine viral diarrhea virus, yellow fever virus, dengue virus, and banzi virus...
  20. Extra-pulmonary pathology caused by avian H5N1 and recombinant H1N1-1918 influenz
    Helle Bielefeldt Ohmann; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  21. The Joint Risks of Hazadous Air Pollulants Among Childhood Cancer Histotypes
    James Thompson; Fiscal Year: 2007
    ..This study will identify the areas of high risk and the associated HAPs exposures, information essential to elucidate the role of HAPs and to guide further study. [unreadable] [unreadable] [unreadable]..
  22. New HCV isolates SBIR
    VICTOR BUCKWOLD; Fiscal Year: 2007
    ..This would help expedite drug development for HCV, leading to improvements in Public Health. [unreadable] [unreadable] [unreadable]..
  23. Ethnobotanical Anti-Respiratory Syncytial Virus Drugs
    Joshua Ojwang; Fiscal Year: 2003
    ..proposed commercial application: not available ..
  24. Viruses And Cells Gordon Conference
    Charles Rice; Fiscal Year: 2005
    ..Funding is requested to support the conference fees for graduate students and postdoctoral fellows to this meeting. ..
  25. MOLECULAR GENETICS OF SINDBIS VIRUS REPLICATION
    Charles Rice; Fiscal Year: 2005
    ....
  26. The Role of Pesticide Dispersion Within Texas Watershed*
    James Thompson; Fiscal Year: 2004
    ..It is anticipated that the results produced will provide the preliminary data needed to continue definitive investigations under the auspices of subsequent R01 funding. ..
  27. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  28. Small Molecules as Research Tools for HCV Biology
    Charles Rice; Fiscal Year: 2004
    ..compounds will be counter-screened against other members of the Flaviviridae family, including bovine viral diarrhea virus and yellow fever virus...
  29. Modeling GBV-B Replication in Immortalized Cell Lines
    VICTOR BUCKWOLD; Fiscal Year: 2003
    ..This will facilitate the discovery and development of new anti-HCV drugs that may improve the quality of life for HCV-infected patients. ..
  30. IMMUNOTHERAPY PROTECTION & VACCINES FOR HEPATITIS C
    Charles Rice; Fiscal Year: 2003
    ..It is believed that much of the information gained in these studies will be applicable to vaccine development for man. ..
  31. STRUCTURE/FUNCTION OF A PREGNANCY ASSOCIATED PROTEIN
    Thomas Hansen; Fiscal Year: 2003
    ..abstract_text> ..

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