Thermotoga maritima MSB8

Summary

Alias: Thermotoga maritima DSM 3109, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8

Top Publications

  1. ncbi Binding of thiostrepton to a complex of 23-S rRNA with ribosomal protein L11
    J Thompson
    Eur J Biochem 98:261-5. 1979
  2. ncbi Cooperative interactions of RNA and thiostrepton antibiotic with two domains of ribosomal protein L11
    Y Xing
    Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Biochemistry 35:1581-8. 1996
  3. ncbi Structure of CheA, a signal-transducing histidine kinase
    A M Bilwes
    Department of Biology, California Institute of Technology, Pasadena 91125, USA
    Cell 96:131-41. 1999
  4. ncbi Crystal structure of a conserved ribosomal protein-RNA complex
    G L Conn
    Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA
    Science 284:1171-4. 1999
  5. ncbi A detailed view of a ribosomal active site: the structure of the L11-RNA complex
    B T Wimberly
    Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA
    Cell 97:491-502. 1999
  6. ncbi EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome
    R K Agrawal
    Wadsworth Center, State University of New York at Albany, 12201 0509, USA
    Nat Struct Biol 6:643-7. 1999
  7. ncbi The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution
    F Mueller
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, Berlin, 14195, Germany
    J Mol Biol 298:35-59. 2000
  8. ncbi Structure of the 30S ribosomal subunit
    B T Wimberly
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Nature 407:327-39. 2000
  9. ncbi Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation
    R K Agrawal
    Wadsworth Center, Empire State Plaza, Albany, NY 12201 0509, USA
    J Mol Biol 311:777-87. 2001
  10. ncbi Structural analysis of DNA replication fork reversal by RecG
    M R Singleton
    ICRF Clare Hall Laboratories, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3LD, United Kingdom
    Cell 107:79-89. 2001

Research Grants

Patents

  1. ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS,NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
  2. COMPOSITIONS AND METHODS FOR PRODUCING CHEMICALS AND DERIVATIVES THEREOF
  3. COMPOSITIONS AND METHODS FOR PRODUCING CHEMICALS AND DERIVATIVES THEREOF
  4. Proteins associated with abiotic stress response and homologs
  5. PRODUCTION OF PERACIDS USING AN ENZYME HAVING PERHYDROLYSIS ACTIVITY
  6. Process for the production of a fine chemical
  7. Proteins associated with abiotic stress response and homologs
  8. ENZYMES AND FORMULATIONS FOR BROAD-SPECIFICITY DECONTAMINATION OF CHEMICAL AND BIOLOGICAL WARFARE AGENTS
  9. Process of producing L-vinylglycine derivatives
  10. HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM

Scientific Experts

Detail Information

Publications103 found, 100 shown here

  1. ncbi Binding of thiostrepton to a complex of 23-S rRNA with ribosomal protein L11
    J Thompson
    Eur J Biochem 98:261-5. 1979
    ..coli or the homologous protein BM-L11 of Bacillus megaterium. In the presence of T1 ribonuclease, protein BM-L11 and thiostrepton protect from degradation a fragment of E. coli 23-S RNA estimated to be about 50 nucleotides in length...
  2. ncbi Cooperative interactions of RNA and thiostrepton antibiotic with two domains of ribosomal protein L11
    Y Xing
    Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Biochemistry 35:1581-8. 1996
    ..L11 function is thus more complex than simple interaction with ribosomal RNA; we suggest that thiostrepton mimics some ribosomal component or factor that normally interacts with the L11 N-terminal domain...
  3. ncbi Structure of CheA, a signal-transducing histidine kinase
    A M Bilwes
    Department of Biology, California Institute of Technology, Pasadena 91125, USA
    Cell 96:131-41. 1999
    ..Different subunit conformations suggest that relative domain motions link receptor response to kinase activity...
  4. ncbi Crystal structure of a conserved ribosomal protein-RNA complex
    G L Conn
    Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA
    Science 284:1171-4. 1999
    ..This direct interaction with a key ribosomal RNA tertiary interaction suggests that part of the role of L11 is to stabilize an unusual RNA fold within the ribosome...
  5. ncbi A detailed view of a ribosomal active site: the structure of the L11-RNA complex
    B T Wimberly
    Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA
    Cell 97:491-502. 1999
    ..These antibiotics are proposed to bind in this cleft, locking the putative switch and interfering with the function of elongation factors...
  6. ncbi EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome
    R K Agrawal
    Wadsworth Center, State University of New York at Albany, 12201 0509, USA
    Nat Struct Biol 6:643-7. 1999
    ..Upon GTP hydrolysis, the bifurcation is reversed and an arc-like connection is formed between the base of the stalk and EF-G...
  7. ncbi The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution
    F Mueller
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, Berlin, 14195, Germany
    J Mol Biol 298:35-59. 2000
    ....
  8. ncbi Structure of the 30S ribosomal subunit
    B T Wimberly
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Nature 407:327-39. 2000
    ..The structure will facilitate the interpretation in molecular terms of lower resolution structural data on several functional states of the ribosome from electron microscopy and crystallography...
  9. ncbi Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation
    R K Agrawal
    Wadsworth Center, Empire State Plaza, Albany, NY 12201 0509, USA
    J Mol Biol 311:777-87. 2001
    ..The results provide a new insight into the mechanism of EF-G-dependent translocation...
  10. ncbi Structural analysis of DNA replication fork reversal by RecG
    M R Singleton
    ICRF Clare Hall Laboratories, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3LD, United Kingdom
    Cell 107:79-89. 2001
    ..We propose a mechanism for how forks are processed by RecG to facilitate replication fork restart. In addition, this structure suggests that the mechanism and function of the two largest helicase superfamilies are distinct...
  11. ncbi Structural basis for contrasting activities of ribosome binding thiazole antibiotics
    Georg Lentzen
    RiboTargets, Ltd, Granta Park, Abington, CB1 6GB, Cambridge, United Kingdom
    Chem Biol 10:769-78. 2003
    ..We have generated a three-dimensional (3D) model for the interaction of thiostrepton with L11BD RNA. The model rationalizes the differences between micrococcin and the thiostrepton-like antibiotics interacting with L11BD...
  12. ncbi Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy
    Mikel Valle
    Howard Hughes Medical Institute, Health Research, Inc at the Wadsworth Center, Empire State Plaza, Albany, New York 12201 0509, USA
    Nat Struct Biol 10:899-906. 2003
    ..From these new findings we propose a mechanism that can explain the sequence of events during the decoding of mRNA on the ribosome...
  13. pmc Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase
    John C Evans
    Department of Biological Chemistry and Biophysics Research Division, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 1055, USA
    Proc Natl Acad Sci U S A 101:3729-36. 2004
    ..To complete the catalytic cycle, the cobalamin-binding domain must travel back and forth between these distant active sites...
  14. ncbi Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima
    Cindy M Quezada
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    J Mol Biol 341:1283-94. 2004
    ..The P1 conformations that we observe are likely relevant to other helical or coiled-coil proteins and may be important for generating switches in signaling processes...
  15. ncbi Crystal structures of the ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon
    Sabine Petry
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Cell 123:1255-66. 2005
    ..Finally, this work demonstrates the feasibility of crystallizing ribosomes with bound factors at a defined state along the translational pathway...
  16. ncbi Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution
    Michael DiDonato
    Joint Center for Structural Genomics, USA
    Proteins 63:256-60. 2006
  17. ncbi Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 A resolution
    Irimpan I Mathews
    Synchrotron Radiation Laboratory, Stanford University, Menlo Park, California, USA
    Proteins 63:1106-11. 2006
  18. pmc Crystal structure of the CorA Mg2+ transporter
    Vladimir V Lunin
    Department of Medical Biophysics, University of Toronto, 112 College Street, Toronto, Ontario M5G 1L6, Canada
    Nature 440:833-7. 2006
    ..An apparent Mg2+ ion was bound between monomers at a conserved site in the cytoplasmic domain, suggesting a mechanism to link gating of the pore to the intracellular concentration of Mg2+...
  19. ncbi Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution
    Said Eshaghi
    Division of Biophysics, Department of Medical Biochemistry and Biophysics, Karolinska Institute, SE 171 77 Stockholm, Sweden
    Science 313:354-7. 2006
    ....
  20. ncbi Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from Thermotoga maritima at 1.90 A resolution
    Irimpan I Mathews
    Stanford Synchrotron Radiation Laboratory, Stanford University, Menlo Park, California, USA
    Proteins 65:249-54. 2006
  21. pmc Complexed structures of formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima describe a novel ATP binding protein superfamily
    Mariya Morar
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA
    Biochemistry 45:14880-95. 2006
    ....
  22. ncbi Functional properties of the thermostable mutL from Thermotoga maritima
    Tae Gyun Kim
    Department of Chemistry, Pohang University of Science and Technology, Pohang 790 784, Korea
    BMB Rep 42:53-8. 2009
    ..The properties of a stable MutL homologue were investigated using a thermostable MutL (TmL) from Thermotoga maritima MSB8 and whose size exclusion chromatographic and crosslinking analyses were compatible with a dimeric form of ..
  23. pmc A structural basis for Mg2+ homeostasis and the CorA translocation cycle
    Jian Payandeh
    Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
    EMBO J 25:3762-73. 2006
    ..A proteolytic protection assay, biophysical data, and comparison to a soluble domain structure from Archaeoglobus fulgidus have revealed the potential reaction coordinate for this diverse family of transport proteins...
  24. pmc Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications
    J R Brown
    Canadian Institute for Advanced Research, Department of Biochemistry, Dalhousie University, Halifax, NS
    Proc Natl Acad Sci U S A 92:2441-5. 1995
    ..vaginalis clustered with other eukaryotic ValRS genes, which may have been transferred from the mitochondrial genome to the nuclear genome, suggesting that this amitochondrial trichomonad once harbored an endosymbiotic bacterium...
  25. pmc Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein
    B L Golden
    Department of Microbiology, Duke University Medical Center, Durham, NC 27710
    EMBO J 12:4901-8. 1993
    ..The domain structure is homologous with several other ribosomal proteins and to a large family of eukaryotic RNA binding proteins...
  26. ncbi Cloning and sequencing of the gene coding for topoisomerase I from the extremely thermophilic eubacterium, Thermotoga maritima
    C Bouthier de la Tour
    Laboratoire d Enzymologie des Acides Nucleiques, Institut de Genetique et Microbiologie, URA 1354, Universite Paris Sud, Orsay, France
    Biochim Biophys Acta 1264:279-83. 1995
    ..Finally, analysis of the regions flanking the gene reveals that Tm TopA is surrounded by two other ORFs, suggesting the occurrence of a polycistronic transcriptional unit...
  27. ncbi Crystallographic analysis of phosphoglycerate kinase from the hyperthermophilic bacterium Thermotoga maritima
    G Auerbach
    Max Planck Institut fur Biochemie, Martinsried, Germany
    Biol Chem 378:327-9. 1997
    ....
  28. ncbi The two faces of the Escherichia coli 23 S rRNA sarcin/ricin domain: the structure at 1.11 A resolution
    C C Correll
    Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA
    J Mol Biol 292:275-87. 1999
    ..This minor groove surface includes the Watson-Crick faces of the cytosine bases in the unusual A2654.C2666 and U2653.C2667 water-mediated base-pairs...
  29. ncbi Thermostability, oligomerization and DNA-binding properties of the regulatory protein ArgR from the hyperthermophilic bacterium Thermotoga neapolitana
    D Dimova
    Laboratoire de Biotechnologie, UPRES Biocatalyse, Faculte des Sciences et des Techniques, Universite de Nantes, France
    Mol Gen Genet 263:119-30. 2000
    ..Our data indicate that genes for arginine biosynthesis are clustered in a putative operon, which could also be regulated by the ArgR protein, in the hyperthermophilic host...
  30. pmc Crystal structure of the cell division protein FtsA from Thermotoga maritima
    F van den Ent
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    EMBO J 19:5300-7. 2000
    ..Elucidation of the crystal structure of FtsA shows that another bacterial protein involved in cytokinesis is structurally related to a eukaryotic cytoskeletal protein involved in cytokinesis...
  31. ncbi Phylogenetic analyses of two "archaeal" genes in thermotoga maritima reveal multiple transfers between archaea and bacteria
    C L Nesbo
    Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Canada
    Mol Biol Evol 18:362-75. 2001
    ..For hyperthermophiles, we hypothesize that LGT may be as much a consequence as the cause of adaptation to hyperthermophily...
  32. ncbi An essential GTPase, der, containing double GTP-binding domains from Escherichia coli and Thermotoga maritima
    J Hwang
    Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 276:31415-21. 2001
    ..The deletion strain was found to form colonies only if the cells harbored a plasmid containing der, indicating that der is essential for E. coli growth...
  33. ncbi Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex
    Holger Stark
    Max Planck Institute for Biophysical Chemistry, 37077 Gottingen, Germany
    Nat Struct Biol 9:849-54. 2002
    ..These results provide a detailed snapshot view of an important functional state of the ribosome and suggest mechanisms of decoding and GTPase activation...
  34. ncbi F- and V-type ATPases in the hyperthermophilic bacterium Thermotoga neapolitana
    Toshii Iida
    Marine Biotechnology Institute, Heita, Kamaishi, Iwate 026 0001, Japan
    Extremophiles 6:369-75. 2002
    ..maritima genome. Evolution of the two types of ATPases in Thermotoga is discussed...
  35. ncbi Structure of the Escherichia coli ribosomal termination complex with release factor 2
    Bruno P Klaholz
    Department of Biological Sciences, Imperial College of Science, Technology and Medicine, London SW7 2AY, UK
    Nature 421:90-4. 2003
    ..By connecting the ribosomal decoding centre with the PTC, RF2 functionally mimics a tRNA molecule in the A site. Translational termination in eukaryotes is likely to be based on a similar mechanism...
  36. ncbi Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Thermotoga maritima through trapping of a covalent glycosyl-enzyme intermediate and mutagenesis
    Chris A Tarling
    Department of Chemistry, University of British Columbia, Vancouver V6T 1Z1, Canada
    J Biol Chem 278:47394-9. 2003
    ..This article presents the first direct identification of the catalytic nucleophile of an alpha-L-fucosidase, a key step in the understanding of these important enzymes...
  37. ncbi Thermotoga maritima-Escherichia coli chimeric topoisomerases. Answers about involvement of the carboxyl-terminal domain in DNA topoisomerase I-mediated catalysis
    Thierry Viard
    Laboratoire d Enzymologie des Acides Nucleiques, Institut de Genetique et Microbiologie, UMR 8621 CNRS, Batiment 400, Universite Paris Sud, Centre d Orsay, 91405 Orsay, France
    J Biol Chem 279:30073-80. 2004
    ....
  38. ncbi Evolutionary links as revealed by the structure of Thermotoga maritima S-adenosylmethionine decarboxylase
    Angela V Toms
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 279:33837-46. 2004
    ..A homology model for the Escherichia coli AdoMetDC was generated based on the structures of the T. maritima and human AdoMetDCs...
  39. ncbi Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 A resolution
    Daniel McMullan
    The Joint Center for Structural Genomics, San Diego, California, USA
    Proteins 56:615-8. 2004
  40. ncbi An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima
    Vivian L Y Yip
    Department of Chemistry, University of British Columbia, Vancouver, BC, Canada V6T 1Z1
    J Am Chem Soc 126:8354-5. 2004
    ..6), provided evidence in support of the proposed mechanism, which has striking resemblances to that of the sugar dehydratases. Furthermore, analysis of the stereochemical outcome indicated that family 4 enzymes are retaining glycosidases...
  41. pmc Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved by gene duplication
    Robert Pejchal
    Department of Biological Chemistry, University of Michigan, Ann Arbor, USA
    PLoS Biol 3:e31. 2005
    ..Structures of the binary substrate complexes imply that rearrangement of folate, perhaps accompanied by domain rearrangement, must occur before formation of a ternary complex that is competent for methyl transfer...
  42. ncbi Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation
    Mihaela Diaconu
    Röntgenkristallographie, Max Planck Institut fur biophysikalische Chemie, Am Fassberg 11, D 37077 Gottingen, Germany
    Cell 121:991-1004. 2005
    ..Highly mobile L7/12 C-terminal domains promote recruitment of translation factors to the ribosome and stimulate GTP hydrolysis by the ribosome bound factors through stabilization of their active GTPase conformation...
  43. ncbi Structural basis of the substrate subsite and the highly thermal stability of xylanase 10B from Thermotoga maritima MSB8
    - Ihsanawati
    Department of Life Science, Tokyo Institute of Technology, Yokohama, Japan
    Proteins 61:999-1009. 2005
    The crystal structure of xylanase 10B from Thermotoga maritima MSB8 (TmxB), a hyperthermostable xylanase, has been solved in its native form and in complex with xylobiose or xylotriose at 1.8 A resolution...
  44. pmc Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer
    Rongguang Zhang
    Biosciences Division, Midwest Center for Structural Genomics, Structural Biology Center, Argonne National Laboratory, Argonne, IL 60439, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 62:335-9. 2006
    ..This 230-amino-acid protein exhibits high structural homology with SAICAR synthase from baker's yeast. The protein structure is described and compared with that of the ATP-SAICAR synthase complex from yeast...
  45. ncbi Reconstruction of the chemotaxis receptor-kinase assembly
    Sang Youn Park
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA
    Nat Struct Mol Biol 13:400-7. 2006
    ..Linking layers of ternary complexes with close-packed receptors generates a lattice with reasonable component ratios, cooperative interactions among receptors and accessible sites for modification enzymes...
  46. pmc Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure
    Dario Segura-Peña
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 South Ashland Avenue, Chicago, IL 60607, USA
    J Mol Biol 369:129-41. 2007
    ..A more open conformation, as seen in the TmTK-TP4A complex structure, is required to provide space for the adenosine moiety. Our analysis supports the formation of an analogous open conformation in hTK1 upon ATP binding...
  47. pmc Glycerate 2-kinase of Thermotoga maritima and genomic reconstruction of related metabolic pathways
    Chen Yang
    Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Bacteriol 190:1773-82. 2008
    ..Both enzymatic activities were experimentally verified, and the entire pathway was validated by its in vitro reconstitution...
  48. pmc Metal active site elasticity linked to activation of homocysteine in methionine synthases
    Markos Koutmos
    Biophysics Research Division, Life Sciences Institute, and Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 105:3286-91. 2008
    ..Specifically, zinc is mobile in the active sites of MetE and MetH, and its dynamic nature helps facilitate the active site conformational changes necessary for thiol activation and methyl transfer...
  49. pmc The structure of a soluble chemoreceptor suggests a mechanism for propagating conformational signals
    Abiola M Pollard
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14850, USA
    Biochemistry 48:1936-44. 2009
    ....
  50. doi New insights into the mechanism of dihydrodipicolinate synthase using isothermal titration calorimetry
    Andrew C Muscroft-Taylor
    Biomolecular Interaction Centre, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
    Biochimie 92:254-62. 2010
    ..These results offer new insights into the inhibition of this enzyme, a validated antibiotic target...
  51. pmc Purification, crystallization and preliminary crystallographic analysis of a thermostable endonuclease IV from Thermotoga maritima
    Ronny C Hughes
    Oak Ridge National Laboratory, Neutron Scattering Science Division, 1 Bethel Valley Road, Oak Ridge, TN 37831, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:1317-9. 2009
    The DNA-repair enzyme endonuclease IV from the thermophilic bacterium Thermotoga maritima MSB8 (reference sequence NC_000853) has been expressed in Escherichia coli and crystallized for X-ray analysis. T...
  52. pmc Structure of the ternary complex formed by a chemotaxis receptor signaling domain, the CheA histidine kinase, and the coupling protein CheW as determined by pulsed dipolar ESR spectroscopy
    Jaya Bhatnagar
    Center for Advanced ESR Studies, Cornell University, Ithaca, New York 14853, USA
    Biochemistry 49:3824-41. 2010
    ..In the context of the hexagonal lattice formed by trimeric transmembrane chemoreceptors, the PDS structure is best accommodated with the P3 domain in the center of a honeycomb edge...
  53. pmc Immobilization of the plug domain inside the SecY channel allows unrestricted protein translocation
    Jelger A Lycklama A Nijeholt
    Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9751 NN Haren, The Netherlands
    J Biol Chem 285:23747-54. 2010
    ..Biochemical characterization of this mutant as well as molecular dynamics simulations suggest that only a limited movement of the plug domain suffices for translocation...
  54. doi Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima
    Takuhiro Ito
    Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    Acta Crystallogr D Biol Crystallogr 66:813-20. 2010
    ..Interestingly, the glutamylation efficiency was not affected even in the presence of excess GatCAB. Therefore, GluRS avoids competition with GatCAB and glutamylates tRNA(Gln)...
  55. pmc OS-FRET: a new one-sample method for improved FRET measurements
    Annette H Erbse
    Department of Chemistry and Biochemistry and Molecular Biophysics Program, University of Colorado, Boulder, CO 80309 0215, USA
    Biochemistry 50:451-7. 2011
    ..Anticipated applications of OS-FRET include analysis of macromolecular structure, binding and conformational dynamics, and high-throughput screening for interactions and inhibitors...
  56. doi Identification of Tyr241 as a key catalytic base in the family 4 glycoside hydrolase BglT from Thermotoga maritima
    Vivian L Y Yip
    2036 Main Mall, Department of Chemistry, University of British Columbia, Vancouver, BC, Canada V6T 1Z1
    Biochemistry 51:8464-74. 2012
    ..This is consistent with a slowing of the deprotonation step upon removal of the base...
  57. pmc Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes
    Susan E Tsutakawa
    Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    J Biol Chem 288:8445-55. 2013
    ..Collectively, the results illuminate the activities of residues, metal ions, and active site features for abasic site endonucleases...
  58. doi A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritima
    Hanan M A Moustafa
    Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA Department of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, El Chatby, Alexandria 21526, Egypt
    Anal Biochem 501:75-81. 2016
    ..The kinetic parameters of Km and kcat are 1.2 mM and 185 s(-1) at 90 °C, respectively. The enzyme has a half-life time of up to 156 min at 90 °C. This enzyme is the most active and thermostable PPM reported to date...
  59. ncbi Structure and mechanism of spermidine synthases
    Hong Wu
    Structural Genomics Consortium, University of Toronto, 100 College Street, Toronto, Ontario, M5G 1L5, Canada
    Biochemistry 46:8331-9. 2007
    ..The studies also provide a structural basis for the specificity of the spermidine synthase subclass of the aminopropyltransferase family...
  60. pmc Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes
    Dario Segura-Peña
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 South Ashland Avenue, Chicago, IL 60607, USA
    Structure 15:1555-66. 2007
    ..We hypothesize that these structural changes are relevant to enzyme function in situ as part of the catalytic cycle and serve an important role in regulating enzyme activity by amplifying the effects of feedback inhibitor binding...
  61. doi Structure of a complex of the ATPase SecA and the protein-translocation channel
    Jochen Zimmer
    Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nature 455:936-43. 2008
    ..SecA binding generates a 'window' at the lateral gate of the SecY channel and it displaces the plug domain, preparing the channel for signal sequence binding and channel opening...
  62. pmc Purification, crystallization and preliminary crystallographic analysis of a 4-thiouridine synthetase-RNA complex
    Peter Thomas Naumann
    Molecular Structural Biology, Georg August University Gottingen, Justus von Liebig Weg 11, 37077 Gottingen, Germany
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:421-4. 2013
    ..5 Å. The crystals belonged to the orthorhombic space group P212121, with unit-cell parameters a = 102.9, b = 112.8, c = 132.8 Å...
  63. ncbi The glnA gene of the extremely thermophilic eubacterium Thermotoga maritima: cloning, primary structure, and expression in Escherichia coli
    A M Sanangelantoni
    Dipartimento di Genetica e Microbiologia A Buzzati Traverso, Universita di Pavia, Italy
    J Gen Microbiol 138:383-93. 1992
    ..Comparison of the amino acid sequence of T. maritima GS with those from thermophilic and mesophilic micro-organisms failed to detect any obvious features directly related to thermal stability...
  64. pmc Phylogenetic analysis of sequences from diverse bacteria with homology to the Escherichia coli rho gene
    T Opperman
    Department of Chemistry, Indiana University, Bloomington 47405
    J Bacteriol 176:5033-43. 1994
    ..Since functionally defective mutants for E. coli Rho exist in all three of these segments, they represent important parts of Rho that have undergone adaptive evolution...
  65. pmc Crystal structure of the ribosomal protein S6 from Thermus thermophilus
    M Lindahl
    Chemical Center, University of Lund, Sweden
    EMBO J 13:1249-54. 1994
    ....
  66. ncbi Highly thermostable endo-1,3-beta-glucanase (laminarinase) LamA from Thermotoga neapolitana: nucleotide sequence of the gene and characterization of the recombinant gene product
    V V Zverlov
    Institute of Molecular Genetics, Russian Academy of Science, Moscow, Russia
    Microbiology 143:1701-8. 1997
    ..Thus, LamA is the most thermostable 1,3-beta-glucanase described to date...
  67. pmc Both DNA gyrase and reverse gyrase are present in the hyperthermophilic bacterium Thermotoga maritima
    O Guipaud
    Laboratoire de Biologie Moléculaire du Gène chez les Extrémophiles, Institut de Genetique et Microbiologie, Universite Paris Sud, 91405 Orsay Cedex, France
    Proc Natl Acad Sci U S A 94:10606-11. 1997
    ..The findings concerning DNA gyrase and negative supercoiling in Thermotogales put into question the role of reverse gyrase in hyperthermophiles...
  68. pmc Reverse gyrase from the hyperthermophilic bacterium Thermotoga maritima: properties and gene structure
    C Bouthier de la Tour
    Laboratoire d Enzymologie des Acides Nucleiques, Institut de Genetique et Microbiologie, Universite Paris Sud, Orsay, France
    J Bacteriol 180:274-81. 1998
    The hyperthermophilic bacterium Thermotoga maritima MSB8 possesses a reverse gyrase whose enzymatic properties are very similar to those of archaeal reverse gyrases...
  69. ncbi Isolation and analysis of genes for amylolytic enzymes of the hyperthermophilic bacterium Thermotoga maritima
    M Bibel
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, Germany
    FEMS Microbiol Lett 158:9-15. 1998
    ..to the previously identified 4-alpha-glucanotransferase gene mgtA and the alpha-amylase gene amyA of Thermotoga maritima strain MSB8 we have now isolated three further genes encoding amylolytic enzymes from a gene library of this ..
  70. ncbi Homo-dimeric recombinant dihydrofolate reductase from Thermotoga maritima shows extreme intrinsic stability
    T Dams
    Institut fur Biophysik und Physikalische Biochemie, Universitat Regensburg, Germany
    Biol Chem 379:367-71. 1998
    ..The apoenzyme was crystallized and a data set was collected to a resolution of about 2 A...
  71. ncbi Homomultimeric protease in the hyperthermophilic bacterium Thermotoga maritima has structural and amino acid sequence homology to bacteriocins in mesophilic bacteria
    P M Hicks
    Department of Chemical Engineering, North Carolina State University, Raleigh 27695 7905, USA
    FEBS Lett 440:393-8. 1998
    ..maritima protease suggests that their antibacterial activity may involve elements of proteolysis, and raises the prospect for antimicrobial ecological strategies in hyperthermophilic niches...
  72. pmc Discontinuous occurrence of the hsp70 (dnaK) gene among Archaea and sequence features of HSP70 suggest a novel outlook on phylogenies inferred from this protein
    S Gribaldo
    Istituto Pasteur Fondazione Cenci Bolognetti, Dipartimento Biotecnologie Cellulari ed Ematologia, Universita di Roma I, Policlinico Umberto I degrees, 00161 Roma, Italy
    J Bacteriol 181:434-43. 1999
    ....
  73. ncbi Does the elimination of ion pairs affect the thermal stability of cold shock protein from the hyperthermophilic bacterium Thermotoga maritima?
    N Frankenberg
    Institut fur Biophysik und Physikalische Biochemie, Universitat Regensburg, Germany
    FEBS Lett 454:299-302. 1999
    ..The results are in agreement with preliminary NMR data which confirm the predicted structure only for the N-terminal ion pair...
  74. ncbi Structure of the C-terminal domain of FliG, a component of the rotor in the bacterial flagellar motor
    S A Lloyd
    Department of Biology, University of Utah, Salt Lake City 84112 0840, USA
    Nature 400:472-5. 1999
    ..On the basis of the disposition of these residues, we present a hypothesis for the orientation of FliG-C domains in the flagellar motor, and propose a structural model for the part of the rotor that interacts with the stator...
  75. pmc The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition
    M Stoldt
    Abteilung Molekulare Biophysik NMR Spektroskopie, Institut fur Molekulare Biotechnologie, Postfach 100813, 07708 Jena, Germany
    EMBO J 18:6508-21. 1999
    ..The structure of the complex reveals that the E-domain RNA serves as a preformed docking partner, while the L25 protein has one preformed and one induced recognition module...
  76. ncbi Thermotoga maritima AglA, an extremely thermostable NAD+-, Mn2+-, and thiol-dependent alpha-glucosidase
    C Raasch
    Institut fur Mikrobiologie und Genetik, Georg August Universitat, Gottingen, Germany
    Extremophiles 4:189-200. 2000
    The gene for the alpha-glucosidase AglA of the hyperthermophilic bacterium Thermotoga maritima MSB8, which was identified by phenotypic screening of a T...
  77. pmc Characterization of GTPase activity of TrmE, a member of a novel GTPase superfamily, from Thermotoga maritima
    K Yamanaka
    Department of Biochemistry, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Bacteriol 182:7078-82. 2000
    ..3 min(-1), respectively. Our results indicate that TrmE is a GTP-binding protein with a very high intrinsic GTP hydrolysis rate. We also propose that TrmE homologues constitute a novel subfamily of the GTPase superfamily...
  78. ncbi Characterization of the full length uracil-DNA glycosylase in the extreme thermophile Thermotoga maritima
    M Sandigursky
    Departments of Radiology and Radiation Oncology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Mutat Res 485:187-95. 2001
    ..We have also demonstrated that TMUDG can substitute for the Escherichia coli uracil-DNA glycosylase and initiate base excision repair using a closed circular DNA substrate containing a unique U:G base pair...
  79. pmc Crystal structure of the bacterial cell division inhibitor MinC
    S C Cordell
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    EMBO J 20:2454-61. 2001
    ..MinC does not act like SulA, which affects the GTPase activity of FtsZ, and the model can explain how MinC would select for the FtsZ polymer rather than the monomer...
  80. ncbi The crystal structure of indoleglycerol-phosphate synthase from Thermotoga maritima. Kinetic stabilization by salt bridges
    Thorsten Knöchel
    Division of Structural Biology, Biozentrum, University Basel, Klingelbergstrasse 70, CH 4056 Basel, Switzerland
    J Biol Chem 277:8626-34. 2002
    ..This observation is consistent with a protein unfolding mechanism where the simultaneous breakdown of all salt bridges is the rate-determining step...
  81. ncbi Differential oligosaccharide recognition by evolutionarily-related beta-1,4 and beta-1,3 glucan-binding modules
    Alisdair B Boraston
    Protein Engineering Network of Centres of Excellence, Edmonton, Alberta, Canada T6G 2S2
    J Mol Biol 319:1143-56. 2002
    ..Thermodynamics interpreted in the light of structural information highlights the differential role of water in the interaction of these CBMs with their respective oligosaccharide ligands...
  82. ncbi Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643
    Zhiru Yang
    Department of Biological Sciences, Columbia University, New York, New York 10027, USA
    J Biol Chem 278:8804-8. 2003
    ..Therefore, our studies demonstrate that two different enzymes, an oxidase and a dehydrogenase, may have evolved to catalyze the first step of NAD biosynthesis in prokaryotes. TM1643 establishes a new class of amino acid dehydrogenases...
  83. pmc Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain
    Darcie J Miller
    Department of Molecular Pharmacology and Biological Chemistry and Drug Discovery Program, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Protein Sci 12:1432-42. 2003
    ..These TM0872 crystal structures offer the first structural glimpses at this phylogenetically conserved sequence family...
  84. pmc Structural analysis of the domain interface in DrrB, a response regulator of the OmpR/PhoB subfamily
    Victoria L Robinson
    Howard Hughes Medical Institute, Center for Advanced Biotechnology and Medicine, and Department of Biochemistry, Robert Wood Johnson Medical School, The University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Bacteriol 185:4186-94. 2003
    ....
  85. ncbi Locking and unlocking of ribosomal motions
    Mikel Valle
    Howard Hughes Medical Institute, and Health Research Incororated at the Wadswoth Center, State University of New York, Albany, 12201, USA
    Cell 114:123-34. 2003
    ..These ribosomal motions can occur only when the P-site tRNA is deacylated. Prior to peptidyl-transfer to the A-site tRNA or peptide removal, the presence of the charged P-site tRNA locks the ribosome and prohibits both of these motions...
  86. ncbi Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 A resolution
    Robert Schwarzenbacher
    Joint Center for Structural Genomics, La Jolla, CA 92037, USA
    Proteins 54:810-3. 2004
  87. ncbi Crystal structure of a ribose-5-phosphate isomerase RpiB (TM1080) from Thermotoga maritima at 1.90 A resolution
    Qingping Xu
    The Joint Center for Structural Genomics, Stanford University, Menlo Park, California, USA
    Proteins 56:171-5. 2004
  88. ncbi NMR for structural proteomics of Thermotoga maritima: screening and structure determination
    Wolfgang Peti
    The Scripps Research Institute, Department of Molecular Biology and Joint Center of Structural Genomics, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Struct Funct Genomics 5:205-15. 2004
    ....
  89. pmc Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain
    Dong Hae Shin
    Berkeley Structural Genomics Center, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 101:13198-203. 2004
    ..The overall structural features of TmYjeQ make it a good candidate for an RNA-binding protein, which is consistent with the biochemical data of the YjeQ subfamily in binding to the ribosome...
  90. pmc High-throughput computational and experimental techniques in structural genomics
    Mark R Chance
    New York Structural Genomics Research Consortium, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Genome Res 14:2145-54. 2004
    ..This projected resource will provide structural biology information important to understanding the function of most proteins of the cell...
  91. ncbi Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX
    Sang Youn Park
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14850, USA
    Mol Cell 16:563-74. 2004
    ..Our structures indicate that the flagellar switch components FliY and FliM resemble CheC more closely than CheX, but attribute phosphatase activity only to FliY...
  92. pmc Structural insights into the first incision reaction during nucleotide excision repair
    James J Truglio
    Department of Pharmacological Sciences, State University of New York at Stony Brook, Stony Brook, NY, USA
    EMBO J 24:885-94. 2005
    ..Structural and biochemical data strongly suggest that the N-terminal endonuclease domain of UvrC utilizes a novel one-metal mechanism to cleave the phosphodiester bond...
  93. ncbi Oligomeric state and mode of self-association of Thermotoga maritima ribosomal stalk protein L12 in solution
    Pierre D J Moens
    School of Biological, Biomedical, and Molecular Sciences, The University of New England, Armidale, New South Wales 2351, Australia
    Biochemistry 44:3298-305. 2005
    ..coli system. The exchange rate increases with increasing temperature and approaches the one observed for the E. coli system at 50 degrees C. Possible factors responsible for this difference are discussed...
  94. ncbi Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM
    Partha P Datta
    Division of Molecular Medicine, Wadsworth Center, New York State Department of Health, Empire State Plaza, P O Box 509, Albany, New York 12201, USA
    Mol Cell 20:723-31. 2005
    ....
  95. ncbi A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation
    Xingjuan Chao
    Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA
    Cell 124:561-71. 2006
    ..A point mutation that dissociates CheC from CheD impairs chemotaxis in vivo. Thus, CheC incorporates an element of an upstream receptor to influence both its own effect on receptor output and that of its binding partner, CheD...
  96. ncbi Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p
    Qingping Xu
    Joint Center for Structural Genomics
    Proteins 65:777-82. 2006
  97. ncbi Biochemical analysis of Thermotoga maritima GH36 alpha-galactosidase (TmGalA) confirms the mechanistic commonality of clan GH-D glycoside hydrolases
    Donald A Comfort
    Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695 7905, USA
    Biochemistry 46:3319-30. 2007
    ..Furthermore, they show that the biochemical characteristics of GH36 TmGalA are closely related to GH27 enzymes, confirming the mechanistic commonality of clan GH-D members...
  98. pmc Crystallization and preliminary crystallographic analysis of an esterase with a novel domain from the hyperthermophile Thermotoga maritima
    Lei Sun
    Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands
    Acta Crystallogr Sect F Struct Biol Cryst Commun 63:777-9. 2007
    ..6 A resolution. The crystal belongs to space group H32, with unit-cell parameters a = b = 130.2, c = 306.2 A. There are two molecules in the asymmetric unit, with a V(M) of 2.9 A3 Da(-1) and 58% solvent content...
  99. pmc Xylanase attachment to the cell wall of the hyperthermophilic bacterium Thermotoga maritima
    Wolfgang Liebl
    Institut fur Mikrobiologie und Genetik, Georg August Universitat, Grisebachstr 8, D 37077 Gottingen, Germany
    J Bacteriol 190:1350-8. 2008
    ..maritima via a hydrophobic peptide anchor, which is highly unusual for an outer membrane protein...
  100. doi Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution
    Qingping Xu
    Joint Center for Structural Genomics, Menlo Park, California, USA
    Proteins 71:1546-52. 2008
  101. pmc Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport
    Matthew J Cuneo
    Department of Biochemistry, Duke University, Medical Center, Durham, North Carolina 27710, USA
    J Biol Chem 283:32812-20. 2008
    ....

Research Grants1

  1. Improving nucleoside phosphorylation with hybrid kinases
    Stefan Lutz; Fiscal Year: 2009
    ..Finally, the structural diversity of the hybrid proteins will be a rich source for fundamental structure-function studies. ..

Patents32

  1. ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS,NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
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  2. COMPOSITIONS AND METHODS FOR PRODUCING CHEMICALS AND DERIVATIVES THEREOF
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  3. COMPOSITIONS AND METHODS FOR PRODUCING CHEMICALS AND DERIVATIVES THEREOF
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  6. Process for the production of a fine chemical
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  7. Proteins associated with abiotic stress response and homologs
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  8. ENZYMES AND FORMULATIONS FOR BROAD-SPECIFICITY DECONTAMINATION OF CHEMICAL AND BIOLOGICAL WARFARE AGENTS
    Patent Number: JP2009517002-A; Date:2009-04-30
  9. Process of producing L-vinylglycine derivatives
    Patent Number: JP2007295865-A; Date:2007-11-15
  10. HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
    Patent Number: JP2007524375-A; Date:2007-08-30
  11. No title supplied
    Patent Number: WO2006056468-A1; Date:2006-06-01
  12. ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS,NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
    Patent Number: JP2013176393-A; Date:2013-09-09
  13. ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS,NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
    Patent Number: JP2010516296-A; Date:2010-05-20
  14. HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
    Patent Number: JP2010284168-A; Date:2010-12-24
  15. PRODUCTION OF PERACIDS USING AN ENZYME HAVING PERHYDROLYSIS ACTIVITY
    Patent Number: JP2011504370-A; Date:2011-02-10
  16. Hydrolases, nucleic acids encoding them and methods for improving paper strength
    Patent Number: EP1869173-A2; Date:2007-12-26
  17. Production of peracids using an enzyme having perhydrolysis activity
    Patent Number: WO2007070609-A2; Date:2007-06-21
  18. Glycosidase Enzymes
    Patent Number: JP2004000189-A; Date:2004-01-08
  19. Process for the control of production of fine chemicals
    Patent Number: EP2199304-A1; Date:2010-06-23
  20. Process for the production of fine chemicals
    Patent Number: EP2194140-A2; Date:2010-06-09
  21. Plants with increased yield (nue)
    Patent Number: WO2010046221-A1; Date:2010-04-29
  22. Method for producing a transgenic plant cell, a plant or a part thereof with increased resistance biotic stress
    Patent Number: WO2010037714-A1; Date:2010-04-08
  23. Plants with increased yield (lt)
    Patent Number: WO2010034672-A1; Date:2010-04-01
  24. Process for the production of lutein
    Patent Number: EP2096177-A2; Date:2009-09-02
  25. Process for the production of a fine chemical
    Patent Number: EP2090662-A2; Date:2009-08-19
  26. Lipid metabolism proteins, combinations of lipid metabolism proteins and uses thereof
    Patent Number: WO2009077406-A1; Date:2009-06-25
  27. Plants with increased yield and/or increased tolerance to environmental stress (iy-bm)
    Patent Number: WO2009077611-A2; Date:2009-06-25
  28. Production of peracids using an enzyme having perhydrolysis activity
    Patent Number: WO2009067279-A1; Date:2009-05-28
  29. Plants with increased yield
    Patent Number: WO2009037329-A2; Date:2009-03-26
  30. Plants with increased yield
    Patent Number: WO2009037279-A1; Date:2009-03-26
  31. Plants with increased tolerance and/or resistance to environmental stress and increased biomass production
    Patent Number: WO2008142034-A2; Date:2008-11-27
  32. Production of peracids using an enzyme having perhydrolysis activity
    Patent Number: WO2008073139-A1; Date:2008-06-19