Sulfolobus islandicus

Summary

Alias: "Sulfolobus islandicus" Zillig et al. 1994

Top Publications

  1. ncbi Halocins and sulfolobicins: the emerging story of archaeal protein and peptide antibiotics
    E M O'Connor
    Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011 5640, USA
    J Ind Microbiol Biotechnol 28:23-31. 2002
  2. doi A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus
    Ling Deng
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK2200, Copenhagen N, Denmark
    Mol Microbiol 87:1088-99. 2013
  3. pmc Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus
    Wenfang Peng
    State Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China
    RNA Biol 10:738-48. 2013
  4. doi Reassortment of CRISPR repeat-spacer loci in Sulfolobus islandicus
    Nicole L Held
    Department of Microbiology, University of Illinois, Urbana Champaign, Urbana, IL, USA
    Environ Microbiol 15:3065-76. 2013
  5. pmc Geographic divergence of "Sulfolobus islandicus" strains assessed by genomic analyses including electronic DNA hybridization confirms they are geovars
    Guanghong Zuo
    T life Research Center, Fudan University, Shanghai, 200433, China
    Antonie Van Leeuwenhoek 105:431-5. 2014
  6. pmc Recombination shapes genome architecture in an organism from the archaeal domain
    David J Krause
    Department of Microbiology, University of Illinois at Urbana Champaign
    Genome Biol Evol 6:170-8. 2014
  7. doi Inter-viral conflicts that exploit host CRISPR immune systems of Sulfolobus
    Susanne Erdmann
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 N, Copenhagen, Denmark
    Mol Microbiol 91:900-17. 2014
  8. pmc An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference
    Wenfang Peng
    State Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, 430070 Wuhan, China Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen N, Denmark
    Nucleic Acids Res 43:406-17. 2015
  9. ncbi [Archaeons--still unknown microorganisms]
    Magdalena Efenberger
    Zakład Immunologii Doświadczalnej, Uniwersytet Medyczny w Łodzi
    Postepy Hig Med Dosw (Online) 68:1452-63. 2014
  10. pmc Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition
    Tao Liu
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, P R China
    Nucleic Acids Res 43:1044-55. 2015

Research Grants

Patents

  1. Modified plants with increased oil content
  2. SULFOLOBAL PHOSPHOTRIESTERASE-LIKE (PLL) LACTONASES ACTIVITY HAVING ENHANCED PROPERTIES AND THE USES THEREOF
  3. Sulfolobal Phosphotriesterase-Like (PLL) lactonases activity having enhanced properties and the uses thereof
  4. Archaeal plasmid vector system
  5. Archaeal plasmid vector system
  6. AN ENZYME FOR THE PREPARATION OF METHYLMALONATE SEMIALDEHYDE

Scientific Experts

  • G Lipps
  • Andrew F Gardner
  • Patrizia Contursi
  • Qihong Huang
  • Eugenio Notomista
  • David Prangishvili
  • Qunxin She
  • Ling Deng
  • C E Blank
  • Xu Peng
  • Gael Erauso
  • P J Keeling
  • Rachel J Whitaker
  • David J Evans
  • Arnulf Kletzin
  • Changyi Zhang
  • Nan Peng
  • Tessa E F Quax
  • Roger A Garrett
  • Yun Xiang Liang
  • Patrick Forterre
  • Nicole L Held
  • Wenfang Peng
  • Silvia Berkner
  • Mart Krupovic
  • David J Krause
  • Yunxiang Liang
  • Yingjun Li
  • REBECCA ETHEL TAUROG
  • Sara Munk Jensen
  • Li Huang
  • Li Guo
  • Mingxia Feng
  • Adeline Goulet
  • Hinsby Cadillo-Quiroz
  • Yuxia Mei
  • Yindi Chu
  • Julien Hiblot
  • Lanming Chen
  • Jamie C Snyder
  • Guennadi Sezonov
  • Guillaume Gotthard
  • Soizick Lucas
  • Ariane Bize
  • Sonja Verena Albers
  • Michael L Reno
  • Kim Brugger
  • Nolan F Sheppard
  • Egor A Vorontsov
  • Carlos León-Sobrino
  • Wenyuan Han
  • Xueguo Song
  • Guannan Liu
  • Elena Rensen
  • Tao Liu
  • Alexander H Treusch
  • Martin Brandl
  • Christer S Ejsing
  • Frank DiMaio
  • Søren Hallstrøm
  • Guanghong Zuo
  • Magdalena Efenberger
  • Jinfeng Ni
  • Yulong Shen
  • Susanne Erdmann
  • Huan Li
  • Alexandra Kessler
  • Markus Zeeb
  • Peng Juan Liang
  • Rachel Y Samson
  • Emmanuelle R J Quemin
  • Carole Jaubert
  • Xavier Didelot
  • Chijioke J Joshua
  • Alfa Herrera
  • Xiang Ao
  • Tao Zheng
  • Dominic Mao
  • Yongmei Hu
  • Susan Fischer
  • Eric Chabriere
  • Mikael Elias
  • Xiyang Li
  • Soley Gudbergsdottir
  • Mark J Young
  • Marie Christine Prevost
  • Zhengjun Chen
  • Kenneth M Flynn
  • Dennis Grogan
  • Blair R Szymczyna

Detail Information

Publications101 found, 100 shown here

  1. ncbi Halocins and sulfolobicins: the emerging story of archaeal protein and peptide antibiotics
    E M O'Connor
    Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011 5640, USA
    J Ind Microbiol Biotechnol 28:23-31. 2002
    ..Finally, archaeocins also are produced by the hyperthermophile "Sulfolobus islandicus"...
  2. doi A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus
    Ling Deng
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK2200, Copenhagen N, Denmark
    Mol Microbiol 87:1088-99. 2013
    ..The archaeon Sulfolobus islandicus REY15A encodes three interference modules, one of type IA and two of type IIIB...
  3. pmc Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus
    Wenfang Peng
    State Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China
    RNA Biol 10:738-48. 2013
    ..The crenarchaeon Sulfolobus islandicus encodes three distinct CRISPR interference modules, including a type IA system and two type IIIB systems: ..
  4. doi Reassortment of CRISPR repeat-spacer loci in Sulfolobus islandicus
    Nicole L Held
    Department of Microbiology, University of Illinois, Urbana Champaign, Urbana, IL, USA
    Environ Microbiol 15:3065-76. 2013
    ..To assess evolutionary dynamics of CRISPR loci, we have sampled a population of closely related Sulfolobus islandicus strains from Kamchatka, Russia at two time points, 10 years apart...
  5. pmc Geographic divergence of "Sulfolobus islandicus" strains assessed by genomic analyses including electronic DNA hybridization confirms they are geovars
    Guanghong Zuo
    T life Research Center, Fudan University, Shanghai, 200433, China
    Antonie Van Leeuwenhoek 105:431-5. 2014
    Ten well-annotated genomes of "Sulfolobus islandicus" strains from different geographic locations have been released at the NCBI database...
  6. pmc Recombination shapes genome architecture in an organism from the archaeal domain
    David J Krause
    Department of Microbiology, University of Illinois at Urbana Champaign
    Genome Biol Evol 6:170-8. 2014
    ..across the chromosomes of ten closely related sympatric strains of the thermoacidophilic archaeon Sulfolobus islandicus. Statistical analyses show that recombination varies across the genome and interacts with selection to ..
  7. doi Inter-viral conflicts that exploit host CRISPR immune systems of Sulfolobus
    Susanne Erdmann
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 N, Copenhagen, Denmark
    Mol Microbiol 91:900-17. 2014
    Infection of Sulfolobus islandicus REY15A with mixtures of different Sulfolobus viruses, including STSV2, did not induce spacer acquisition by the host CRISPR immune system...
  8. pmc An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference
    Wenfang Peng
    State Key Laboratory of Agricultural Microbiology and College of Life Science and Technology, Huazhong Agricultural University, 430070 Wuhan, China Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK 2200 Copenhagen N, Denmark
    Nucleic Acids Res 43:406-17. 2015
    ..To investigate the in vivo mechanism of RNA interference by two type III-B systems (Cmr-α and Cmr-β) in Sulfolobus islandicus, a genetic assay was developed using plasmids carrying an artificial mini-CRISPR (AC) locus with a single ..
  9. ncbi [Archaeons--still unknown microorganisms]
    Magdalena Efenberger
    Zakład Immunologii Doświadczalnej, Uniwersytet Medyczny w Łodzi
    Postepy Hig Med Dosw (Online) 68:1452-63. 2014
    ..Some archaeons, such as Haloferax mediterranei and Sulfolobus islandicus can synthesize antimicrobial agents which are called archaeocins...
  10. pmc Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition
    Tao Liu
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, P R China
    Nucleic Acids Res 43:1044-55. 2015
    ..Here we examine the transcriptional regulation of the conserved spacer acquisition genes in Type I-A of Sulfolobus islandicus REY15A...
  11. doi Structural characterization of ether lipids from the archaeon Sulfolobus islandicus by high-resolution shotgun lipidomics
    Sara Munk Jensen
    Department of Biology and Nordic Center for Earth Evolution, University of Southern Denmark, Odense, Denmark Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark
    J Mass Spectrom 50:476-87. 2015
    ..shotgun lipidomics to characterize, for the first time, the lipid complement of the archaeon Sulfolobus islandicus. To support the identification of lipids in S...
  12. pmc Efficient 5'-3' DNA end resection by HerA and NurA is essential for cell viability in the crenarchaeon Sulfolobus islandicus
    Qihong Huang
    State Key Laboratory of Microbial Technology, Shandong University, 27 Shanda Nan Rd, Jinan, 250100, P R China
    BMC Mol Biol 16:2. 2015
    ..Here we employed Sulfolobus islandicus, a hyperthermophilic archaeon, as a model to investigate the in vivo functions of the ATPase/helicase HerA,..
  13. doi Virology. A virus that infects a hyperthermophile encapsidates A-form DNA
    Frank DiMaio
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    Science 348:914-7. 2015
    ..The nonenveloped, rod-shaped virus SIRV2 (Sulfolobus islandicus rod-shaped virus 2) infects the hyperthermophilic acidophile Sulfolobus islandicus, which lives at 80°C ..
  14. pmc The Effects of Temperature and Growth Phase on the Lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii
    Sara Munk Jensen
    Department of Biology and Nordic Center for Earth Evolution, University of Southern Denmark, Odense 5230, Denmark
    Life (Basel) 5:1539-66. 2015
    ..used shotgun lipidomics to study this effect as well as the influence of growth phase on the lipidomes of Sulfolobus islandicus and Sulfolobus tokodaii for the first time...
  15. pmc The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules
    Eugenio Notomista
    Dipartimento di Biologia, Universita degli Studi di Napoli Federico II, Complesso Universitario Monte S Angelo, Via Cinthia, 80126, Naples, Italy
    Microb Cell Fact 14:126. 2015
    ..Cationic antimicrobial peptides (CAMPs) are small positively charged peptides with an amphipathic structure, active against Gram-positive and Gram-negative bacteria, fungi, as well as protozoa...
  16. pmc Harnessing Type I and Type III CRISPR-Cas systems for genome editing
    Yingjun Li
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China
    Nucleic Acids Res 44:e34. 2016
    ..Here, a method was developed to repurpose both CRISPR-Cas systems for genetic manipulation in Sulfolobus islandicus, a thermophilic archaeon...
  17. doi Transcriptome changes in STSV2-infected Sulfolobus islandicus REY15A undergoing continuous CRISPR spacer acquisition
    Carlos León-Sobrino
    Archaea Centre, Department of Biology, University of Copenhagen, Copenhagen, DK 2200, Denmark
    Mol Microbiol 99:719-28. 2016
    A transcriptome study was performed on Sulfolobus islandicus REY15A actively undergoing CRISPR spacer acquisition from the crenarchaeal monocaudavirus STSV2 in rich and basal media over a 6 day period...
  18. pmc The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease
    Nolan F Sheppard
    Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, USA
    RNA 22:216-24. 2016
    ..associated component of the Cmr effector complex, but is necessary for DNA silencing by the Cmr system in Sulfolobus islandicus. To investigate the function of the Csx1 protein, we characterized the activity of recombinant Pyrococcus ..
  19. pmc The apt/6-Methylpurine Counterselection System and Its Applications in Genetic Studies of the Hyperthermophilic Archaeon Sulfolobus islandicus
    Changyi Zhang
    Department of Microbiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA Carl R Woese Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Appl Environ Microbiol 82:3070-81. 2016
    b>Sulfolobus islandicus serves as a model for studying archaeal biology as well as linking novel biology to evolutionary ecology using functional population genomics...
  20. pmc Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugated Sulfolobus species
    Guannan Liu
    Archaea Centre, Department of Biology, University of Copenhagen, DK 2200 Copenhagen N, Denmark
    Nucleic Acids Res 44:4233-42. 2016
    ..Here we examined the conjugation cycle of pKEF9 in the recipient strain Sulfolobus islandicus REY15A...
  21. doi Knockout and functional analysis of two DExD/H-box family helicase genes in Sulfolobus islandicus REY15A
    Xueguo Song
    State Key Laboratory of Microbial Technology, Shandong University, 27 Shanda Nan Rd, Jinan, 250100, China
    Extremophiles 20:537-46. 2016
    ..In this study, we attempted gene knockout of 8 putative DExD/H-box helicases in Sulfolobus islandicus REY15A and obtained two deletion mutants, SiRe_0681 and SiRe_1605...
  22. pmc Abundant Lysine Methylation and N-Terminal Acetylation in Sulfolobus islandicus Revealed by Bottom-Up and Top-Down Proteomics
    Egor A Vorontsov
    From the Structural Mass Spectrometry and Proteomics Unit, Structural Biology and Chemistry Department, Institut Pasteur, 75015 Paris, France
    Mol Cell Proteomics 15:3388-3404. 2016
    ..The data have been deposited to the ProteomeXchange with identifiers PXD003074 and PXD004179...
  23. pmc A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction
    Wenyuan Han
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen Biocenter, DK 2200 Copenhagen N, Denmark
    Nucleic Acids Res . 2016
    ..The Sulfolobus islandicus type III-B Cmr-α system targets invading nucleic acid at both RNA and DNA levels and DNA targeting relies ..
  24. pmc Functional characterization of the origin of replication of pRN1 from Sulfolobus islandicus REN1H1
    Chijioke J Joshua
    Department of Plant and Microbial Biology, University of California, Berkeley, Berkeley, California, United States of America Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America Joint BioEnergy Institute, Emeryville, California, United States of America
    PLoS ONE 8:e84664. 2013
    Plasmid pRN1 from Sulfolobus islandicus REN1H1 is believed to replicate by a rolling circle mechanism but its origin and mechanism of replication are not well understood...
  25. ncbi Folding and association of an extremely stable dimeric protein from Sulfolobus islandicus
    Markus Zeeb
    Laboratorium für Biochemie III, Universitat Bayreuth, D 95440 Bayreuth, Germany
    J Mol Biol 336:227-40. 2004
    ORF56 is a plasmid-encoded protein from Sulfolobus islandicus, which probably controls the copy number of the pRN1 plasmid by binding to its own promotor...
  26. ncbi Characterization of the Sulfolobus host-SSV2 virus interaction
    Patrizia Contursi
    Department of Biological Chemistry, Institute of Molecular Biology and Physiology, University of Copenhagen, Copenhagen, Denmark
    Extremophiles 10:615-27. 2006
    ..In this paper we report the findings of a comparative study of SSV2 physiology in the natural host, Sulfolobus islandicus REY15/4, versus the foreign host, Sulfolobus solfataricus, and provide evidence of differently regulated ..
  27. pmc First insights into the entry process of hyperthermophilic archaeal viruses
    Emmanuelle R J Quemin
    Institut Pasteur, Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Departement de Microbiologie, Paris, France
    J Virol 87:13379-85. 2013
    ..we present the first study focusing on the primary interactions between the archaeal rod-shaped virus Sulfolobus islandicus rod-shaped virus 2 (SIRV2) (family Rudiviridae) and its hyperthermoacidophilic host, S. islandicus...
  28. doi Knockouts of RecA-like proteins RadC1 and RadC2 have distinct responses to DNA damage agents in Sulfolobus islandicus
    Peng Juan Liang
    State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China
    J Genet Genomics 40:533-42. 2013
    ..In this study, we performed phylogenetic and genetic analysis of two RadC proteins from Sulfolobus islandicus. RadC is closer to the KaiC lineage of cyanobacteria and proteobacteria than to the lineage of the ..
  29. ncbi Characterisation of the novel restriction endonuclease SuiI from Sulfolobus islandicus
    Stefan Söllner
    Institute of Biochemistry, University of Bayreuth, Universitatstrasse 30, 95447 Bayreuth, Germany
    Extremophiles 10:629-34. 2006
    A restriction endonuclease activity from Sulfolobus islandicus REN2H1 was purified by phosphocellulose and cation exchange chromatography...
  30. doi Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host
    Yuxia Mei
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, People s Republic of China
    Appl Microbiol Biotechnol 93:1965-74. 2012
    A protein expression system recently developed for the thermophilic crenarchaeon Sulfolobus islandicus was employed to produce recombinant protein for EstA, a thermophilic esterase encoded in the same organism...
  31. pmc Modulation of CRISPR locus transcription by the repeat-binding protein Cbp1 in Sulfolobus
    Ling Deng
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200N Copenhagen K, Denmark
    Nucleic Acids Res 40:2470-80. 2012
    ..cbp1 gene deletion from Sulfolobus islandicus REY15A produced a strong reduction in pre-crRNA yields from CRISPR loci but did not inhibit the foreign ..
  32. pmc Patterns of gene flow define species of thermophilic Archaea
    Hinsby Cadillo-Quiroz
    Department of Microbiology and Institute for Genomic Biology, University of Illinois, Urbana Champaign, Urbana, Illinois, United States of America
    PLoS Biol 10:e1001265. 2012
    ..we use high-throughput genome sequencing to identify ongoing speciation in the thermoacidophilic Archaeon Sulfolobus islandicus. Patterns of homologous gene flow among genomes of 12 strains from a single hot spring in Kamchatka, ..
  33. pmc Genomic evidence of rapid, global-scale gene flow in a Sulfolobus species
    Dominic Mao
    Department of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA
    ISME J 6:1613-6. 2012
    Local populations of Sulfolobus islandicus diverge genetically with geographical separation, and this has been attributed to restricted transfer of propagules imposed by the unfavorable spatial distribution of acidic geothermal habitat...
  34. doi A broadly applicable gene knockout system for the thermoacidophilic archaeon Sulfolobus islandicus based on simvastatin selection
    Changyi Zhang
    Department of Microbiology, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Microbiology 158:1513-22. 2012
    ..Interesting patterns of natural variation among Sulfolobus islandicus strains have been identified through genome sequencing...
  35. pmc A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon Sulfolobus islandicus
    Nan Peng
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People s Republic of China
    Appl Environ Microbiol 78:5630-7. 2012
    ..Here we report a versatile vector that confers high levels of protein expression in Sulfolobus islandicus, a hyperthermophilic crenarchaeon...
  36. pmc An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA
    Susan Fischer
    Department of Biology II, Ulm University, 89069 Ulm, Germany
    J Biol Chem 287:33351-63. 2012
    ..their molecular details have so far only been examined in three archaeal species: Sulfolobus solfataricus, Sulfolobus islandicus, and Pyrococcus furiosus...
  37. pmc Structural and enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus
    Julien Hiblot
    URMITE UMR CNRS IRD 6236, IFR48, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 7:e47028. 2012
    A new member of the Phosphotriesterase-Like Lactonases (PLL) family from the hyperthermophilic archeon Sulfolobus islandicus (SisLac) has been characterized...
  38. pmc Identification and characterization of a highly conserved crenarchaeal protein lysine methyltransferase with broad substrate specificity
    Yindi Chu
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, China
    J Bacteriol 194:6917-26. 2012
    ..crenarchaeal protein lysine methyltransferase, designated aKMT, from the hyperthermophilic crenarchaeon Sulfolobus islandicus. The enzyme was capable of transferring methyl groups to selected lysine residues in a substrate protein ..
  39. pmc Insights into a viral lytic pathway from an archaeal virus-host system
    Jamie C Snyder
    Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, Montana, USA
    J Virol 87:2186-92. 2013
    Archaeal host cells infected by Sulfolobus turreted icosahedral virus (STIV) and Sulfolobus islandicus rod-shaped virus 2 (SIRV2) produce unusual pyramid-like structures on the cell surface prior to virus-induced cell lysis...
  40. doi Genetic manipulation in Sulfolobus islandicus and functional analysis of DNA repair genes
    Changyi Zhang
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, People s Republic of China
    Biochem Soc Trans 41:405-10. 2013
    Recently, a novel gene-deletion method was developed for the crenarchaeal model Sulfolobus islandicus, which is a suitable tool for addressing gene essentiality in depth...
  41. doi Genomics and biology of Rudiviruses, a model for the study of virus-host interactions in Archaea
    David Prangishvili
    Institut Pasteur, Department of Microbiology, 25 rue du Dr Roux, Paris 75015, France
    Biochem Soc Trans 41:443-50. 2013
    ..In addition, a revised genome annotation of SIRV2 (Sulfolobus islandicus rod-shaped virus 2) is presented...
  42. doi Sulfolobus islandicus: a model system for evolutionary genomics
    Changyi Zhang
    Department of Microbiology, University of Illinois at Urbana Champaign, 601 S Goodwin Ave, Urbana, IL 61801, USA
    Biochem Soc Trans 41:458-62. 2013
    b>Sulfolobus islandicus has been developed as a model system for combining approaches of evolutionary and molecular biology in Archaea...
  43. pmc Specificity and function of archaeal DNA replication initiator proteins
    Rachel Y Samson
    Sir William Dunn School of Pathology, Oxford University, South Parks Road, Oxford OX1 3RE, UK
    Cell Rep 3:485-96. 2013
    ..We find that the three origins in the single chromosome of the archaeon Sulfolobus islandicus are specified by distinct initiation factors...
  44. pmc Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon
    Carole Jaubert
    Departement de Microbiologie, Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, Paris, France
    Open Biol 3:130010. 2013
    The 2 465 177 bp genome of Sulfolobus islandicus LAL14/1, host of the model rudivirus SIRV2, was sequenced. Exhaustive comparative genomic analysis of S. islandicus LAL14/1 and the nine other completely sequenced S...
  45. pmc Massive activation of archaeal defense genes during viral infection
    Tessa E F Quax
    Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, Paris, France or
    J Virol 87:8419-28. 2013
    ..The Sulfolobus islandicus rod-shaped virus 2 (SIRV2) is a model to study virus-host interactions in Archaea...
  46. pmc Augmenting the genetic toolbox for Sulfolobus islandicus with a stringent positive selectable marker for agmatine prototrophy
    Changyi Zhang
    Department of Microbiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Appl Environ Microbiol 79:5539-49. 2013
    ..In particular, Sulfolobus islandicus provides a powerful opportunity to explore natural variation via experimental functional genomics...
  47. ncbi Complete nucleotide sequence of the Sulfolobus islandicus multicopy plasmid pRN1
    P J Keeling
    Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia, Canada
    Plasmid 35:141-4. 1996
    The complete sequence of the 5350-bp plasmid pRN1 from the crenarchaeote Sulfolobus islandicus has been determined...
  48. ncbi Biochemical and phylogenetic characterization of the dUTPase from the archaeal virus SIRV
    D Prangishvili
    Max Planck Institute for Biochemistry, Am Klopferspitz 18a, 82152 Martinsried, Federal Republic of Germany
    J Biol Chem 273:6024-9. 1998
    The derived amino acid sequence from a 474-base pair open reading frame in the genome of the Sulfolobus islandicus rod-shaped virus SIRV shows striking similarity to bacterial dCTP deaminases and to dUTPases from eukaryotes, bacteria, ..
  49. ncbi Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry
    P J Keeling
    Department of Biology, Indiana University, Bloomington 47405, USA
    Extremophiles 2:391-3. 1998
    The complete sequence of the plasmid pRN2 from the thermoacidophile Sulfolobus islandicus has been determined. The plasmid was found to be circular and 6959 bp in length. S...
  50. pmc Molecular analysis of pDL10 from Acidianus ambivalens reveals a family of related plasmids from extremely thermophilic and acidophilic archaea
    A Kletzin
    Institute of Microbiology and Genetics, Darmstadt University of Technology, 64287 Darmstadt, Germany
    Genetics 152:1307-14. 1999
    ..The pDL10 Rep protein shared 45-80% identical residues with homologous protein genes encoded by the Sulfolobus islandicus plasmids pRN1 and pRN2...
  51. ncbi The genetic element pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus
    H P Arnold
    Max Planck Institut fur Biochemie, 82152 Martinsried, Germany
    Mol Microbiol 34:217-26. 1999
    A new Sulfolobus islandicus strain, REY15/4, harboured both a novel fusellovirus, SSV2, and a small plasmid, pSSVx. The plasmid spread in S...
  52. ncbi A novel lipothrixvirus, SIFV, of the extremely thermophilic crenarchaeon Sulfolobus
    H P Arnold
    Max Planck Institut fur Biochemie, Martinsried, 82152, Germany
    Virology 267:252-66. 2000
    We describe a novel lipothrixvirus, SIFV, of the crenarchaeotal archaeon Sulfolobus islandicus. SIFV (S. islandicus filamentous virus) has a linear virion with a linear double-stranded DNA genome...
  53. pmc Sulfolobicins, specific proteinaceous toxins produced by strains of the extremely thermophilic archaeal genus Sulfolobus
    D Prangishvili
    Max Plank Institute für Biochemie, 82152 Martinsried, Germany
    J Bacteriol 182:2985-8. 2000
    Several novel strains of "Sulfolobus islandicus" produced proteinaceous toxins, termed sulfolobicins, which killed cells of other strains of the same species, as well as of Sulfolobus solfataricus P1 and Sulfolobus shibatae B12, but not ..
  54. ncbi Evolution of the family of pRN plasmids and their integrase-mediated insertion into the chromosome of the crenarchaeon Sulfolobus solfataricus
    X Peng
    Microbial Genome Group Institute of Molecular Biology, University of Copenhagen, Solvgade 83H, Copenhagen, DK 1307, Denmark
    J Mol Biol 303:449-54. 2000
    Plasmid pHEN7 from Sulfolobus islandicus was sequenced (7.83 kb) and shown to belong to the archaeal pRN family, which includes plasmids pRN1, pRN2, pSSVx and pDL10 that share a large conserved sequence region...
  55. pmc pING family of conjugative plasmids from the extremely thermophilic archaeon Sulfolobus islandicus: insights into recombination and conjugation in Crenarchaeota
    K M Stedman
    Max Planck Institut fur Biochemie, D 82152 Martinsried, Germany
    J Bacteriol 182:7014-20. 2000
    ..The efficient occurrence of these recombination processes is further evidence for the striking plasticity of the Sulfolobus genome...
  56. pmc Thermostable and site-specific DNA binding of the gene product ORF56 from the Sulfolobus islandicus plasmid pRN1, a putative archael plasmid copy control protein
    G Lipps
    University of Bayreuth, Biochemistry II, Universitatsstrasse 30, D 95447 Bayreuth, Germany
    Nucleic Acids Res 29:904-13. 2001
    ..we report on the product of the gene orf56 from plasmid pRN1 of the acidophilic and thermophilic archaeon Sulfolobus islandicus. orf56 has not been characterised yet but low sequence similarily to several eubacterial plasmid-encoded ..
  57. pmc The protein ORF80 from the acidophilic and thermophilic archaeon Sulfolobus islandicus binds highly site-specifically to double-stranded DNA and represents a novel type of basic leucine zipper protein
    G Lipps
    University Bayreuth, Biochemistry II, Universitatsstrasse 30, 95447 Bayreuth, Germany
    Nucleic Acids Res 29:4973-82. 2001
    The cryptic high copy number plasmid pRN1 from the thermophilic and acidophilic crenarchaeote Sulfolobus islandicus shares three conserved open reading frames with other S.islandicus plasmids...
  58. pmc A novel type of replicative enzyme harbouring ATPase, primase and DNA polymerase activity
    Georg Lipps
    Department of Biochemistry, University of Bayreuth, Universitatsstrasse 30, Germany
    EMBO J 22:2516-25. 2003
    ..The protein ORF904, encoded by the plasmid pRN1 from the thermoacidophile archaeon Sulfolobus islandicus, is a highly compact multifunctional enzyme with ATPase, primase and DNA polymerase activity...
  59. ncbi Structure of a bifunctional DNA primase-polymerase
    Georg Lipps
    Institute of Biochemistry, University of Bayreuth, Universitatsstrasse 30, D 95447 Bayreuth, Germany
    Nat Struct Mol Biol 11:157-62. 2004
    ..activities are combined, however, in newly identified replicases from archaeal plasmids, such as pRN1 from Sulfolobus islandicus. Here we present a structure-function analysis of the pRN1 primase-polymerase (prim-pol) domain...
  60. ncbi The replication protein of the Sulfolobus islandicus plasmid pRN1
    G Lipps
    Biochemistry, University of Bayreuth, Universitatstrasse 30, 95447 Bayreuth, Germany
    Biochem Soc Trans 32:240-4. 2004
    ..This domain constitutes the first member of the DNA polymerase family E. Based on the biochemical characterization of the gene products a model of how pRN1 is replicated in vivo is proposed...
  61. pmc Transcription of the rod-shaped viruses SIRV1 and SIRV2 of the hyperthermophilic archaeon sulfolobus
    Alexandra Kessler
    Department of Microbiology, University of Regensburg, Regensburg, Germany
    J Bacteriol 186:7745-53. 2004
    ..analysis of gene expression of these viruses at different time points after infection of the host cell, Sulfolobus islandicus, and of the mapping of transcriptional start sites...
  62. ncbi Site-specific binding of the 9.5 kilodalton DNA-binding protein ORF80 visualized by atomic force microscopy
    M Lysetska
    Lehrstuhl für Physikalische Chemie II and Lehrstuhl für Biochemie, Universitat Bayreuth, 95440 Bayreuth, Germany
    Biomacromolecules 6:1252-7. 2005
    ..The measurements allow an estimate of the stoichiometry of the DNA-protein complexes. In contrast to previous results, the single-molecule experiments suggest that only a low number of ORF80 molecules bind to a DNA-binding site...
  63. ncbi Recombination shapes the natural population structure of the hyperthermophilic archaeon Sulfolobus islandicus
    Rachel J Whitaker
    Department of Plant and Microbial Biology, University of California, Berkeley, USA
    Mol Biol Evol 22:2354-61. 2005
    ..We investigated the genetic structure of a thermoacidophilic crenarchaeal species, Sulfolobus islandicus, using multilocus sequence analysis of six variable protein-coding loci on a set of 60 isolates from the ..
  64. ncbi Two novel conjugative plasmids from a single strain of Sulfolobus
    Gael Erauso
    Laboratory of Microbiology, Wageningen University, The Netherlands
    Microbiology 152:1951-68. 2006
    Two conjugative plasmids (CPs) were isolated and characterized from the same 'Sulfolobus islandicus' strain, SOG2/4. The plasmids were separated from each other and transferred into Sulfolobus solfataricus...
  65. pmc Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV)
    Adeline Goulet
    Architecture et Fonction des Macromolecules Biologiques, CNRS and Universités d Aix Marseille I et II, UMR 6098, Case 932, 163 Avenue de Luminy, 13288 Marseille Cedex 9, France
    Acta Crystallogr Sect F Struct Biol Cryst Commun 62:884-6. 2006
    ..1, c = 132.4 A. Diffraction data were collected to a maximum acceptable resolution of 2.95 and 3.20 A for the SeMet-labelled and native protein, respectively...
  66. pmc A spreadable, non-integrative and high copy number shuttle vector for Sulfolobus solfataricus based on the genetic element pSSVx from Sulfolobus islandicus
    Tiziana Aucelli
    Istituto di Biochimica delle Proteine, Via P Castellino 111, 80131 CNR, Napoli, Italy
    Nucleic Acids Res 34:e114. 2006
    The pSSVx genetic element from Sulfolobus islandicus REY15/4 is a hybrid between a plasmid and a fusellovirus, able to be maintained in non-integrative form and to spread when the helper SSV2 virus is present in the cells...
  67. pmc An active nonautonomous mobile element in Sulfolobus islandicus REN1H1
    Silvia Berkner
    Department of Biochemistry, University of Bayreuth, 95440 Bayreuth, Germany
    J Bacteriol 189:2145-9. 2007
    In the crenarchaeote Sulfolobus islandicus REN1H1, a mobile element of 321 bp length has been shown to be active. It does not contain terminal inverted repeats and transposes by a replicative mechanism...
  68. pmc Characterization of the transcriptional activity of the cryptic plasmid pRN1 from Sulfolobus islandicus REN1H1 and regulation of its replication operon
    Silvia Berkner
    Department of Biochemistry, University of Bayreuth, 95440 Bayreuth, Germany
    J Bacteriol 189:1711-21. 2007
    The plasmid pRN1 from Sulfolobus islandicus REN1H1 belongs to the crenarchaeal plasmid family pRN...
  69. pmc Small multicopy, non-integrative shuttle vectors based on the plasmid pRN1 for Sulfolobus acidocaldarius and Sulfolobus solfataricus, model organisms of the (cren-)archaea
    Silvia Berkner
    Department of Biochemistry, University of Bayreuth, 95440 Bayreuth, Germany
    Nucleic Acids Res 35:e88. 2007
    ..of a series of Sulfolobus-Escherichia coli shuttle vectors based on the small multicopy plasmid pRN1 from Sulfolobus islandicus. Selection in suitable uracil auxotrophs is provided through inclusion of pyrEF genes in the plasmid...
  70. pmc Transcriptional analysis of the genetic element pSSVx: differential and temporal regulation of gene expression reveals correlation between transcription and replication
    Patrizia Contursi
    Dipartimento di Biologia Strutturale e Funzionale, Universita degli Studi di Napoli Federico II, Complesso Universitario Monte S Angelo, Via Cinthia, Napoli, Italy
    J Bacteriol 189:6339-50. 2007
    pSSVx from Sulfolobus islandicus strain REY15/4 is a hybrid between a plasmid and a fusellovirus...
  71. pmc Structure of the acidianus filamentous virus 3 and comparative genomics of related archaeal lipothrixviruses
    Gisle Vestergaard
    Centre for Comparative Genomics and Danish Archaea Centre, Department of Molecular Biology, Biocenter, Copenhagen University, Ole Maaløes Vej 5, DK 2200 Copenhagen N, Denmark
    J Virol 82:371-81. 2008
    ..over large regions, with this similarity extending partly to the earlier described betalipothrixvirus Sulfolobus islandicus filamentous virus...
  72. doi Evidence for the horizontal transfer of an integrase gene from a fusellovirus to a pRN-like plasmid within a single strain of Sulfolobus and the implications for plasmid survival
    Xu Peng
    Danish Archaea Centre, Department of Molecular Biology, Biocenter, Copenhagen University, Ole Maaløes Vej 5, Copenhagen N, Denmark
    Microbiology 154:383-91. 2008
    ..This is believed to be the first report of a pRN plasmid sharing its natural host with a fusellovirus and carrying a highly similar integrase gene...
  73. doi Molecular biology of the pRN1 plasmid from Sulfolobus islandicus
    Georg Lipps
    University of Applied Sciences of Northwestern Switzerland FHNW, School of Life Sciences, Institute of Chemistry and Bioanalytics, Gründenstrasse 40, 4132 Muttenz, Switzerland
    Biochem Soc Trans 37:42-5. 2009
    The pRN1 plasmid is a rather small multicopy plasmid which was isolated from a Sulfolobus islandicus strain in 1993 by Wolfram Zillig and co-workers...
  74. doi Genetic analyses in the hyperthermophilic archaeon Sulfolobus islandicus
    Qunxin She
    Danish Archaea Centre, Department of Biology, University of Copenhagen, Biocenter, Ole Maaloes Vej 5, DK 2200 Copenhagen N, Denmark
    Biochem Soc Trans 37:92-6. 2009
    ..In the last few years, we have focused on developing genetic systems for Sulfolobus islandicus using pyrEF as a selection marker and versatile genetic tools have been developed, including methods for ..
  75. doi Viral biogeography revealed by signatures in Sulfolobus islandicus genomes
    Nicole L Held
    Department of Microbiology, University of Illinois, Urbana Champaign, Urbana, IL 61801, USA
    Environ Microbiol 11:457-66. 2009
    ..The biogeographic distribution of viruses that infect Sulfolobus islandicus is investigated using genome comparisons among four newly identified, integrated, Sulfolobus spindle-..
  76. pmc Synergy of NMR, computation, and X-ray crystallography for structural biology
    Blair R Szymczyna
    Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA
    Structure 17:499-507. 2009
    ..overall strategy for rapidly determining the structure of the coat protein C-terminal domain from the Sulfolobus islandicus rod-shaped virus (SIRV)...
  77. pmc Biogeography of the Sulfolobus islandicus pan-genome
    Michael L Reno
    Department of Microbiology and Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Proc Natl Acad Sci U S A 106:8605-10. 2009
    ..Through population-scale comparative genomics of 7 Sulfolobus islandicus genomes from 3 locations, we demonstrate the biogeographical structure of the pan-genome of this species, ..
  78. doi Unmarked gene deletion and host-vector system for the hyperthermophilic crenarchaeon Sulfolobus islandicus
    Ling Deng
    Huazhong Agricultural University, Wuhan, People s Republic of China
    Extremophiles 13:735-46. 2009
    b>Sulfolobus islandicus is being used as a model for studying archaeal biology, geo-biology and evolution. However, no genetic system is available for this organism. To produce an S...
  79. pmc Structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1
    Florence Guillière
    Institut Pasteur, Unité de RMN des Biomolécules, CNRS URA 2185, 75015 Paris, France
    J Biol Chem 284:22222-37. 2009
    ..SvtR (formerly called gp08) from the rod-shaped virus SIRV1, which infects the hyperthermophilic archaeon Sulfolobus islandicus that thrives at 85 degrees C in hot acidic springs. The protein forms a dimer in solution...
  80. pmc A unique virus release mechanism in the Archaea
    Ariane Bize
    Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 106:11306-11. 2009
    ..Here, we demonstrate that the virions of the archaeal Sulfolobus islandicus rod-shaped virus 2 (SIRV2) are released from the host cell through a mechanism, involving the formation of ..
  81. doi Exploitation of plant and archaeal viruses in bionanotechnology
    David J Evans
    Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK
    Biochem Soc Trans 37:665-70. 2009
    ..SIRV2 (Sulfolobus islandicus rod-shaped virus 2), is a robust archaeal virus, resistant to high temperature and low pH...
  82. doi Structure-based stability analysis of an extremely stable dimeric DNA binding protein from Sulfolobus islandicus
    Ulrich Weininger
    Institut fur Physik, Biophysik, Martin Luther Universitat Halle Wittenberg, D 06120 Halle Saale, Germany
    Biochemistry 48:10030-7. 2009
    ORF56 is a small and thermodynamically extremely stable dimeric protein from the archaeon Sulfolobus islandicus. This DNA binding protein is encoded on plasmid pRN1 and possibly controls the copy number of the plasmid...
  83. doi An upstream activation element exerting differential transcriptional activation on an archaeal promoter
    Nan Peng
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China
    Mol Microbiol 74:928-39. 2009
    ..of the Sulfolobus solfataricus araS gene encoding an arabinose binding protein was characterized using an Sulfolobus islandicus reporter gene system...
  84. pmc Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage
    Adeline Goulet
    Architecture et Fonction des Macromolecules Biologiques, Centre national de la Recherche Scientifique and Universités Aix Marseille I and II, Architecture et Fonction des Macromolecules Biologiques, Unite Mixte de Recherche 6098, Case 932, 163 Avenue de Luminy, 13288 Marseille Cedex 9, France
    Proc Natl Acad Sci U S A 106:21155-60. 2009
    ..The four-helix bundle fold of the MCPs from AFV1 is identical to that of the coat protein (CP) of Sulfolobus islandicus rod-shaped virus (SIRV), a member of the Rudiviridae family...
  85. doi The Sulfolobus rod-shaped virus 2 encodes a prominent structural component of the unique virion release system in Archaea
    Tessa E F Quax
    Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, 75724 Paris Cedex 15, France
    Virology 404:1-4. 2010
    ..Here we present results of a protein analysis of Sulfolobus islandicus cells infected with the rudivirus SIRV2, which enable us to postulate SIRV2-encoded protein P98 as the ..
  86. doi Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method
    Changyi Zhang
    State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, PR China
    Microbiology 156:3386-97. 2010
    ..To study the mechanism of archaeal sliding clamps, we sought to generate knockouts for each pcna gene in Sulfolobus islandicus, a hyperthermophilic crenarchaeon, but failed with two conventional knockout methods...
  87. doi Transcription termination in the plasmid/virus hybrid pSSVx from Sulfolobus islandicus
    Patrizia Contursi
    Archaeal Genetics Laboratory, Department of Molecular Biology, University of Copenhagen, Copenhagen Biocenter Ole Maaløes Vej 5, 2200, Copenhagen N, Denmark
    Extremophiles 14:453-63. 2010
    The pSSVx from Sulfolobus islandicus, strain REY15/4, is a hybrid between a plasmid and a fusellovirus...
  88. pmc Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus
    Kenneth M Flynn
    Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, USA
    Genome Biol Evol 2:859-69. 2010
    ..Therefore, in this genus of Archaea as well as in many Bacteria, evolutionary rates and variation in genome content associate with replication timing...
  89. pmc Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers
    Soley Gudbergsdottir
    Archaea Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200N Copenhagen, Denmark
    Mol Microbiol 79:35-49. 2011
    ..pyrE/pyrF genes and transformed into uracil auxotrophic hosts derived from Sulfolobus solfataricus P2 or Sulfolobus islandicus REY15A...
  90. doi C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor family
    Patrizia Contursi
    Dipartimento di Biologia Strutturale e Funzionale, Universita degli Studi di Napoli Federico II, Complesso Universitario Monte S Angelo, Via Cinthia, Naples, Italy
    Biochem J 435:157-66. 2011
    The genetic element pSSVx from Sulfolobus islandicus, strain REY15/4, is a hybrid between a plasmid and a fusellovirus. This plasmid-virus hybrid infects several species of the hyperthermophilic acidophilic crenarchaeon Sulfolobus...
  91. doi Archaeal promoter architecture and mechanism of gene activation
    Nan Peng
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, 430070 Wuhan, Hubei, China
    Biochem Soc Trans 39:99-103. 2011
    Sulfolobus solfataricus and Sulfolobus islandicus contain several genes exhibiting D-arabinose-inducible expression and these systems are ideal for studying mechanisms of archaeal gene expression...
  92. pmc Genome analyses of Icelandic strains of Sulfolobus islandicus, model organisms for genetic and virus-host interaction studies
    Li Guo
    Archaea Centre, Department of Biology, Copenhagen University, Ole Maaløes Vej 5, DK 2200N Copenhagen, Denmark
    J Bacteriol 193:1672-80. 2011
    The genomes of two Sulfolobus islandicus strains obtained from Icelandic solfataras were sequenced and analyzed. Strain REY15A is a host for a versatile genetic toolbox...
  93. pmc Simple and elegant design of a virion egress structure in Archaea
    Tessa E F Quax
    Institut Pasteur, Biologie Moléculaire du Gène chez les Extrêmophiles, 75015 Paris, France
    Proc Natl Acad Sci U S A 108:3354-9. 2011
    ..Here we describe in detail the structure and composition of VAPs formed by the Sulfolobus islandicus rod-shaped virus 2 (SIRV2) in cells of its hyperthermophilic archaeal host...
  94. pmc Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus islandicus lactonase
    Guillaume Gotthard
    Architecture et Fonction des Macromolecules Biologiques, CNRS Aix Marseille Universite, 13288 Marseille, France
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:354-7. 2011
    ..of the PLL family has been identified (SisPox) and its gene was cloned from the hyperthermophilic archeon Sulfolobus islandicus. Owing to its hyperthermostable architecture, SisPox appears to be a good candidate for engineering ..
  95. doi Exceptional virion release mechanism: one more surprise from archaeal viruses
    David Prangishvili
    Institut Pasteur, Department of Microbiology, Biologie Moléculaire du Gène chez les Extrêmophiles, 75015 Paris, France
    Curr Opin Microbiol 14:315-20. 2011
    ..Here we summarize available data on the extraordinary egress mechanism exploited by the Sulfolobus islandicus rod-shaped virus SIRV2 and the Sulfolobus turreted icosahedral virus STIV...
  96. pmc Characterization of Sulfolobus islandicus rod-shaped virus 2 gp19, a single-strand specific endonuclease
    Andrew F Gardner
    New England Biolabs, Inc, Ipswich, MA 01938, USA
    Extremophiles 15:619-24. 2011
    The hyperthermophilic Sulfolobus islandicus rod-shaped virus 2 (SIRV2) encodes a 25-kDa protein (SIRV2gp19) annotated as a hypothetical protein with sequence homology to the RecB nuclease superfamily...
  97. doi Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control
    Xiyang Li
    State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
    J Genet Genomics 38:253-9. 2011
    ..in vivo role of archaeal topo III, we constructed and characterized a topo III gene deletion mutant of Sulfolobus islandicus. The mutant was viable but grew more slowly than the wild-type strain, especially in a nutrient-poor ..
  98. pmc Biochemical characterization of a structure-specific resolving enzyme from Sulfolobus islandicus rod-shaped virus 2
    Andrew F Gardner
    New England Biolabs, Inc, Ipswich, Massachusetts, United States of America
    PLoS ONE 6:e23668. 2011
    b>Sulfolobus islandicus rod shaped virus 2 (SIRV2) infects the archaeon Sulfolobus islandicus at extreme temperature (70°C-80°C) and acidity (pH 3)...
  99. pmc Development of a simvastatin selection marker for a hyperthermophilic acidophile, Sulfolobus islandicus
    Tao Zheng
    State Key Laboratory of Microbial Technology, Shandong University, Jinan, People s Republic of China
    Appl Environ Microbiol 78:568-74. 2012
    We report here a novel selectable marker for the hyperthermophilic crenarchaeon Sulfolobus islandicus. The marker cassette is composed of the sac7d promoter and the hmg gene coding for the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) ..
  100. doi An expansion of age constraints for microbial clades that lack a conventional fossil record using phylogenomic dating
    Carrine E Blank
    Department of Geosciences, University of Montana, 32 Campus Drive 1296, Missoula, MT 59812 1296, USA
    J Mol Evol 73:188-208. 2011
    ..Similar analyses also predicted that the ancestor to the Sulfolobus solfataricus-Sulfolobus islandicus clade was able to metabolize phenol using catechol dioxygenase, so this clade was assigned a maximum age ..
  101. pmc Genomic comparison of archaeal conjugative plasmids from Sulfolobus
    Bo Greve
    Danish Archaea Centre, Institute of Molecular Biology, Copenhagen University, Sølvgade 83H, DK 1307 Copenhagen K, Denmark
    Archaea 1:231-9. 2004
    ....

Research Grants1

  1. Biochemical and structural characterization of self-assembling viral particles
    REBECCA ETHEL TAUROG; Fiscal Year: 2010
    The Sulfolobus islandicus rod-shaped virus (SIRV) is a fibrous virus that infects thermophilic, acidophilic Archaea found in thermal vents and hot springs around the world...

Patents6

  1. Modified plants with increased oil content
    Patent Number: JP2014531194-A; Date:2014-11-27
  2. SULFOLOBAL PHOSPHOTRIESTERASE-LIKE (PLL) LACTONASES ACTIVITY HAVING ENHANCED PROPERTIES AND THE USES THEREOF
    Patent Number: WO2014167140-A1; Date:2014-10-16
  3. Sulfolobal Phosphotriesterase-Like (PLL) lactonases activity having enhanced properties and the uses thereof
    Patent Number: EP2789344-A1; Date:2014-10-15
  4. Archaeal plasmid vector system
    Patent Number: EP1990417-A1; Date:2008-11-12
  5. Archaeal plasmid vector system
    Patent Number: WO2008138579-A1; Date:2008-11-20
  6. AN ENZYME FOR THE PREPARATION OF METHYLMALONATE SEMIALDEHYDE
    Patent Number: WO2011157573-A2; Date:2011-12-22