Ruta

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Top Publications

  1. ncbi Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada
    Cheryl Lans
    BCICS, University of Victoria, British Columbia V8W 2Y2, Canada
    Vet Parasitol 148:325-40. 2007
  2. ncbi Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts
    A Logarto Parra
    Drug Research and Development Center CIDEM, Biologic Research Department, Ciudad de La Habana, Cuba
    Phytomedicine 8:395-400. 2001
  3. doi Application of chitin and chitosan as elicitors of coumarins and fluoroquinolone alkaloids in Ruta graveolens L. (common rue)
    Aleksandra Orlita
    Faculty of Chemistry, University of Gdansk, ul Sobieskiego 18, PL 80 952 Gdansk, Poland
    Biotechnol Appl Biochem 51:91-6. 2008
  4. ncbi In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders
    Fernando Calzada
    Unidad de Investigación Médica en Farmacología de Productos Naturales, Hospital de Pediatria, 2 Piso, Centro Medico Nacional Siglo XXI, IMSS, Av Cuauhtemoc 330, Col Doctores, CP 06725, Mexico, DF, Mexico
    J Ethnopharmacol 108:367-70. 2006
  5. ncbi Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine
    K B Hari Kumar
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala State, India
    Asian Pac J Cancer Prev 8:98-102. 2007
  6. ncbi Clastogenic potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells
    Korengath C Preethi
    Department of Biochemistry, Amala Cancer Research Centre, Kerala, India
    Asian Pac J Cancer Prev 9:763-9. 2008
  7. ncbi Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model
    T Erkinaro
    Department of Anaesthesiology, University Hospital of Oulu, PO Box 21, FIN 90029 OYS, Finland
    Br J Anaesth 93:825-32. 2004
  8. doi Chemical composition and antioxidant potential of Ruta montana L. essential oil from Algeria
    N Kambouche
    Organic Synthesis Laboratory, Chemistry Department, Sciences Faculty, Essenia University, Oran, Algeria
    J Med Food 11:593-5. 2008
  9. ncbi Rue the herb: Ruta graveolens--associated phytophototoxicity
    Kimberly Eickhorst
    Department of Dermatology, St Luke s Roosevelt Hospital, New York, NY, USA
    Dermatitis 18:52-5. 2007
  10. doi Phylogenetic relationships of Ruteae (Rutaceae): new evidence from the chloroplast genome and comparisons with non-molecular data
    Gabriele Salvo
    Institute of Systematic Botany, University of Zurich, Zollikerstrasse 107, Ch 8008 Zurich, Switzerland
    Mol Phylogenet Evol 49:736-48. 2008

Scientific Experts

Detail Information

Publications146 found, 100 shown here

  1. ncbi Ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in British Columbia, Canada
    Cheryl Lans
    BCICS, University of Victoria, British Columbia V8W 2Y2, Canada
    Vet Parasitol 148:325-40. 2007
    ..Ranunculaceae), Juglans nigra L. (Juglandaceae), Olea europaea L. (Oleaceae) and Ruta graveolens L. (Rutaceae)). Stomach problems were treated with: Achillea millefolium L. (Asteraceae), Aloe vera (L...
  2. ncbi Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts
    A Logarto Parra
    Drug Research and Development Center CIDEM, Biologic Research Department, Ciudad de La Habana, Cuba
    Phytomedicine 8:395-400. 2001
    ..Plantaginaceae); Plectranthus amboinicus (Lour.) Spreng. (Lamiaceae); Ruta graveolens L. (Rutaceae); Senna alata (L.) Roxb. (Fabaceae); Stachytarpheta jamaicensis (L...
  3. doi Application of chitin and chitosan as elicitors of coumarins and fluoroquinolone alkaloids in Ruta graveolens L. (common rue)
    Aleksandra Orlita
    Faculty of Chemistry, University of Gdansk, ul Sobieskiego 18, PL 80 952 Gdansk, Poland
    Biotechnol Appl Biochem 51:91-6. 2008
    Common rue (Ruta graveolens L.) accumulates various types of secondary metabolites, such as coumarins furanocoumarins, acridone and quinolone alkaloids and flavonoids...
  4. ncbi In vitro susceptibility of Entamoeba histolytica and Giardia lamblia to plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders
    Fernando Calzada
    Unidad de Investigación Médica en Farmacología de Productos Naturales, Hospital de Pediatria, 2 Piso, Centro Medico Nacional Siglo XXI, IMSS, Av Cuauhtemoc 330, Col Doctores, CP 06725, Mexico, DF, Mexico
    J Ethnopharmacol 108:367-70. 2006
    ..Dorstenia contrajerva, Senna villosa and Ruta chalepensis were the most active toward Giardia lamblia with IC50 < 38 microg/ml...
  5. ncbi Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine
    K B Hari Kumar
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala State, India
    Asian Pac J Cancer Prev 8:98-102. 2007
    ..We have used Ruta, Hydrastis, Lycopodium and Thuja, which are commonly employed in homeopathy for treating cancer...
  6. ncbi Clastogenic potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells
    Korengath C Preethi
    Department of Biochemistry, Amala Cancer Research Centre, Kerala, India
    Asian Pac J Cancer Prev 9:763-9. 2008
    b>Ruta graveolens belonging to family Rutaceae has long been traditionally used as a medicinal plant as well as a flavoring agent in food. However, very little data are available on the toxicity of the plant...
  7. ncbi Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model
    T Erkinaro
    Department of Anaesthesiology, University Hospital of Oulu, PO Box 21, FIN 90029 OYS, Finland
    Br J Anaesth 93:825-32. 2004
    ..We hypothesized that ephedrine and phenylephrine, administered for maternal hypotension following fetal hypoxaemia, are equal in respect of fetal outcome...
  8. doi Chemical composition and antioxidant potential of Ruta montana L. essential oil from Algeria
    N Kambouche
    Organic Synthesis Laboratory, Chemistry Department, Sciences Faculty, Essenia University, Oran, Algeria
    J Med Food 11:593-5. 2008
    The essential oil of aerial parts of Ruta montana L. growing in the Oran region in the west of Algeria was obtained by hydrodistillation with a 1.63% yield on a dry weight basis...
  9. ncbi Rue the herb: Ruta graveolens--associated phytophototoxicity
    Kimberly Eickhorst
    Department of Dermatology, St Luke s Roosevelt Hospital, New York, NY, USA
    Dermatitis 18:52-5. 2007
    We describe an unusual case of phytophototoxicity induced by an herbal plant, Ruta graveolens, from the Rutaceae family. This common herb, also called rue, can be found throughout rural settings in the United States...
  10. doi Phylogenetic relationships of Ruteae (Rutaceae): new evidence from the chloroplast genome and comparisons with non-molecular data
    Gabriele Salvo
    Institute of Systematic Botany, University of Zurich, Zollikerstrasse 107, Ch 8008 Zurich, Switzerland
    Mol Phylogenet Evol 49:736-48. 2008
    ..The phylogenetic analyses determined that Haplophyllum and Ruta form reciprocally exclusive monophyletic groups and that Dictamnus is not closely related to the other genera of ..
  11. ncbi Inhibition of lipopolysaccharide-inducible nitric oxide synthase and IL-1beta through suppression of NF-kappaB activation by 3-(1'-1'-dimethyl-allyl)-6-hydroxy-7-methoxy-coumarin isolated from Ruta graveolens L
    Sunil Kumar Raghav
    Proteomics and Structural Biology Division, Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110 007, India
    Eur J Pharmacol 560:69-80. 2007
    The Ruta graveolens L. plant is used in traditional medicine to treat a large number of diseases...
  12. ncbi Transvaginal Doppler-guided uterine artery occlusion for the treatment of symptomatic fibroids: summary results from two pilot studies
    George A Vilos
    Department of Obstetrics and Gynecology, St Joseph s Health Care, London, ON
    J Obstet Gynaecol Can 32:149-54. 2010
    ..To evaluate the feasibility, safety, and short-term efficacy of bilateral uterine artery occlusion, using a transvaginal Doppler-guided vascular clamp as a minimally invasive therapy for symptomatic uterine leiomyomas...
  13. pmc Characterization of rice anthranilate synthase alpha-subunit genes OASA1 and OASA2. Tryptophan accumulation in transgenic rice expressing a feedback-insensitive mutant of OASA1
    Y Tozawa
    National Agriculture Research Center, 3 1 1 Kannondai, Tsukuba, Ibaraki 305 8666, Japan
    Plant Physiol 126:1493-506. 2001
    ..AS alpha-subunits from various species revealed a close evolutionary relationship among OASA1 and Arabidopsis ASA2, Ruta graveolens AS alpha 2, and tobacco ASA2, whereas OASA2, Arabidopsis ASA1, and R...
  14. ncbi Effect of Ruta graveolens L. and Euphorbia peplus L. anti-inflammatory extracts on nutritional status of rats and the safety of their use
    Sahar Y Al-Okbi
    Food Sciences and Nutrition Department, National Research Centre, Dokki, Cairo, Egypt
    Indian J Exp Biol 40:45-8. 2002
    ..graveolens. The results suggest that both plant extracts have no harmful effect on nutritional status and are safe towards kidney functions, while Euphorbia is more safe than Ruta in relation to liver functions.
  15. ncbi Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid
    Anna Oliva
    Department of Life Science, Second University of Naples, Via Vivaldi 43, 81100 Naples, Italy
    J Agric Food Chem 51:890-6. 2003
    Bioassay-directed isolation of antifungal compounds from an ethyl acetate extract of Ruta graveolens leaves yielded two furanocoumarins, one quinoline alkaloid, and four quinolone alkaloids, including a novel compound, 1-methyl-2-[6'-(3' '..
  16. ncbi Ruta graveolens aqueous extract retards mouse preimplantation embryo development
    Jorge L Gutierrez-Pajares
    Laboratorio de Reproducción y Biología del Desarrollo, Facultad de Ciencias Biologicas, Universidad Nacional Mayor de San Marcos, Lima, Peru
    Reprod Toxicol 17:667-72. 2003
    This work was undertaken to examine possible embryotoxicity of Ruta graveolens (rue), a plant used by indigenous communities for the purposes of therapeutic and fertility regulation...
  17. ncbi Medicinal plant use in the Bredasdorp/Elim region of the Southern Overberg in the Western Cape Province of South Africa
    T S A Thring
    Department of Biodiversity and Conservation Biology, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa
    J Ethnopharmacol 103:261-75. 2006
    ..A more structured questionnaire was used to determine which plants were most popular for particular ailments. It was found that Artemisia afra and Ruta graveolens were the most popular.
  18. ncbi Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells
    S K Raghav
    Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110007, India
    J Ethnopharmacol 104:234-9. 2006
    b>Ruta graveolens L. (Rutaceae) is used for several therapeutic purposes worldwide...
  19. ncbi Inhibitory effects of Ruta graveolens L. extract on guinea pig liver aldehyde oxidase
    Saieed Pirouzpanah
    School of Health and Nutrition, Tabriz University of Medical Sciences, Iran
    Chem Pharm Bull (Tokyo) 54:9-13. 2006
    b>Ruta graveolens L. is a flavonoid-containing medicinal plant with various biological properties. In the present study, the effects of R. graveolens extract on aldehyde oxidase, a molybdenum hydroxylase, are investigated...
  20. ncbi An acridone-producing novel multifunctional type III polyketide synthase from Huperzia serrata
    Kiyofumi Wanibuchi
    School of Pharmaceutical Sciences and the COE 21 Program, University of Shizuoka, Japan
    FEBS J 274:1073-82. 2007
    ..Interestingly, Hu. serrata polyketide synthase 1 lacks most of the consensus active site sequences with acridone synthase from Ruta graveolens (Rutaceae).
  21. ncbi Long-term outcome from uterine fibroid embolization with tris-acryl gelatin microspheres: results of a multicenter study
    James B Spies
    Department of Radiology, Georgetown University Hospital, 3800 Reservoir Rd NW, CG 201, Washington, DC 20007 2197, USA
    J Vasc Interv Radiol 18:203-7. 2007
    ..To determine the long-term outcome of uterine fibroid therapy (UFE) using tris-acryl gelatin microspheres (TAGM)...
  22. ncbi 'Translation is not enough': using the Global Person Generated Index (GPGI) to assess individual quality of life in Bangladesh, Thailand, and Ethiopia
    Laura Camfield
    Wellbeing in Developing Countries ESRC Research Group, University of Bath, Bath BA2 7AY, UK
    Qual Life Res 16:1039-51. 2007
    ..The GPGI is based on the widely used Patient Generated Index (Ruta, Camfield, & Martin, (2004) Quality of Life Research, 13, 1545...
  23. pmc 4-Phenoxybutoxy-substituted heterocycles--a structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3
    Silke B Bodendiek
    Department of Pharmacology, University of California, Davis, Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Davis, CA 95616, USA
    Eur J Med Chem 44:1838-52. 2009
    ..Using 5-methoxypsoralen (5-MOP, 1), a compound isolated from Ruta graveolens, as a template we previously synthesized 5-(4-phenoxybutoxy)psoralen (PAP-1, 2) which inhibits Kv1...
  24. doi Repellent activity of plant-derived compounds against Amblyomma cajennense (Acari: Ixodidae) nymphs
    Sara Fernandes Soares
    Centro de Parasitologia Veterinária, Escola de Veterinaria, Universidade Federal de Goias UFG, Campus II Samambaia, Caixa Postal 131, 74001 970 Goiania, GO, Brazil
    Vet Parasitol 167:67-73. 2010
    ..Cymbopogon nardus, Spiranthera odoratissima, Chenopodium ambrosioides, Ageratum conyzoides, Mentha pulegium, Ruta graveolens, and Memora nodosa were studied. Among these the extract of C...
  25. ncbi Oxidative profile in patients with colon cancer: effects of Ruta chalepensis L
    R Acquaviva
    Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy
    Eur Rev Med Pharmacol Sci 15:181-91. 2011
    To verify the involvement of free radicals in tumor progression and to investigate the effects of an ethanolic extract of Ruta Chalepensis L. and of rutin in blood of patients with colon cancer.
  26. ncbi [Toxic hepatitis due to the use of Ruta herbal medicine]
    Elena Rabaev
    Department of Family Medicine, Dimona Dalet Clalit Health Services, Beer Sheba, Israel
    Harefuah 150:235-6, 305. 2011
    ..In this case report, we present an example of toxic hepatitis due to use of Ruta herbal medicine, an unfamiliar side effect of the common herbal medicine Ruta.
  27. ncbi Larvicidal and cytotoxic activities of extracts from 11 native plants from northeastern Mexico
    Yael C de la Torre Rodríguez
    Departamento de Químicas Analítica, Facultad de Medicina, Ave Universidad s n, Cd Universitaria, San Nicolas de los Garza, Nuevo León CP 66451, Mexico
    J Med Entomol 50:310-3. 2013
    ..and Zanthoxylum fagara (L.), and both ether and methanol extracts of Ruta chalepensis L. were significantly larvicidal toward the dengue mosquito after 24 h of exposure...
  28. pmc Effects of clonality on the genetic variability of rare, insular species: the case of Ruta microcarpa from the Canary Islands
    M Meloni
    Institute of Systematic Botany, University of Zurich Zollikerstrase 107, Zurich, 8008, Switzerland
    Ecol Evol 3:1569-79. 2013
    ..polymorphic microsatellite markers to study the genetic structure of the critically endangered insular endemic Ruta microcarpa. We found that clonality appears to positively affect the genetic diversity of R...
  29. doi Monodimensional (GC-FID and GC-MS) and comprehensive two-dimensional gas chromatography for the assessment of volatiles and fatty acids from Ruta chalepensis aerial parts
    Laura Tedone
    Dipartimento di Scienze del Farmaco e dei Prodotti per la Salute, Universita degli Studi di Messina, Viale Annunziata, 98168, Messina, Italy
    Phytochem Anal 25:468-75. 2014
    b>Ruta chalepensis L. (Rutaceae) is widespread in the Mediterranean area. This plant has a solid tradition in ethnomedicine because of its various biological activities. Based on previous reports, the main volatile constituents of R...
  30. pmc Antinociceptive, anti-inflammatory and antipyretic activities of the leaf methanol extract of Ruta graveolens L. (Rutaceae) in mice and rats
    Firdows Loonat
    Discipline of Pharmacology, School of Pharmacy, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa
    Afr J Tradit Complement Altern Med 11:173-81. 2014
    b>Ruta graveolens has been used to treat toothache, earache, rheumatism and fever with little scientific evidence corroborating these uses.
  31. doi Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves
    Tutik Sri Wahyuni
    Division of Microbiology, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe 650 0017, Japan Department of Pharmacognocy and Phytochemistry, Faculty of Pharmacy, Airlangga University, Jl Dharmawangsa Dalam, Surabaya 60286, Indonesia
    Fitoterapia 99:276-83. 2014
    ..In this study, we examined extracts, their subfractions and isolated compounds of Ruta angustifolia leaves for antiviral activities against HCV in cell culture...
  32. doi DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by Ruta graveolens in human colon cancer cells
    Shagun Arora
    Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh, India Electronic address
    Homeopathy 104:36-47. 2015
    In the present study, we investigated the anti-cancer effect of various potencies of Ruta graveolens (Ruta) on COLO-205 cell line, as evidenced by cytotoxicity, migration, clonogenecity, morphological and biochemical changes and ..
  33. doi Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo
    Samrat Ghosh
    Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, West Bengal, India
    J Integr Med 13:34-44. 2015
    ..In this study, efficacy of ethanolic extract of Ruta graveolens (RG) on skin melanoma cells (A375) in vitro and on 7,12-dimethylbenz(a)anthracene (DMBA)-induced skin ..
  34. doi Immobilising effect of Ruta graveolens L. on human spermatozoa: coumarin compounds are involved
    Z Naghibi Harat
    IVF Center, Arash Women Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Andrologia 47:1183-9. 2015
    This study was designed to find out Ruta graveolens L. functional components, which have immobilisation effect on human spermatozoa for contraceptive use...
  35. doi New species of the genus Ypsiloncyphon (Insecta: Coleoptera: Scirtidae: Scirtinae)
    Hiroyuki Yoshitomi
    Entomological Laboratory, Faculty of Agriculture, Ehime University, Tarumi 3 5 7, Matsuyama, 790 8566 Japan Email
    Zootaxa 3904:451-500. 2015
    ..n., and Y. cervus sp. n. Additional specimens of Ypsiloncyphon mendosus (Klausnitzer, 1980), Y. luteoapicalis (Ruta, 2007) and Y. micans (Klausnitzer, 1973) are recorded. Species group IV is newly proposed...
  36. pmc Ruta graveolens L. induces death of glioblastoma cells and neural progenitors, but not of neurons, via ERK 1/2 and AKT activation
    Maria Teresa Gentile
    Laboratory of Molecular and Cellular Pathology, Department of Environmental, Biological and Pharmaceutical Science and Technologies, Second University of Naples, Caserta, Italy
    PLoS ONE 10:e0118864. 2015
    ..Here, we report that the water extract of Ruta graveolens L...
  37. ncbi In vitro antifungal activity of the essential oil and the methanolic extract of Ruta chalepensis
    Ch Aouadhi
    Laboratoire d épidémiologie et microbiologie vétérinaire, Groupes de Bactériologie et Développement Biotechnologique Institut Pasteur de Tunis, Université El Manar
    Arch Inst Pasteur Tunis 90:39-46. 2013
    b>Ruta chalepensis L...
  38. pmc Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings
    Luis Águila
    Center of Neurosciences and Peptides Biology CEBIOR BIOREN, Faculty of Medicine, University of La Frontera, Temuco, Chile
    Biol Res 48:28. 2015
    b>Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others...
  39. pmc Phylogenetic Relationships and Evolution of the Androecia in Ruteae (Rutaceae)
    Lai Wei
    College of Life Sciences, Beijing Normal University, Xinjiekouwai Street, Beijing, China State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Xiangshan, Beijing, China
    PLoS ONE 10:e0137190. 2015
    b>Ruta, which belongs to tribe Ruteae, is the type genus of the subfamily Rutoideae and the family Rutaceae...
  40. ncbi Antiproliferative Effects of Various Furanoacridones Isolated from Ruta graveolens on Human Breast Cancer Cell Lines
    Zsuzsanna Schelz
    Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary
    Anticancer Res 36:2751-8. 2016
    Thanks to its biologically active constituents, Ruta graveolens L. (Rutaceae) is a widely used medicinal plant...
  41. doi [Not Available]
    Emilio Villa-González
    Departamento de Cultura Física Facultad de Ciencias de la Salud Universidad Nacional de Chimborazo Riobamba, Ecuador PROFITH PROmoting FITness and Health through physical activity grupo de investigación Departamento de Educación Física y Deportiva Facultad de Ciencias del Deporte Universidad de Granada
    Nutr Hosp 33:283. 2016
    ..mediante la utilización de dos programas diferentes:Google MapsTM y Sistema de Información Geográfica (GIS) en ruta y en línea recta...
  42. doi Chemical Composition, Antibacterial and Phytotoxic Activities of Peganum harmala Seed Essential Oils from Five Different Localities in Northern Africa
    Ida Apostolico
    Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano Salerno, Italy
    Molecules 21:. 2016
    ..Lepidium sativum L., and Ruta graveolens L. The results showed that both germination and radical elongation were sensitive to the oils.
  43. ncbi Bioactivity of Ruta graveolens and Satureja montana Essential Oils on Solanum tuberosum Hairy Roots and Solanum tuberosum Hairy Roots with Meloidogyne chitwoodi Co-cultures
    Jorge M S Faria
    Centro de Estudos do Ambiente e do Mar Lisboa, Faculdade de Ciencias, Universidade de Lisboa, CBV, C2, Piso 1, Campo Grande, 1749 016 Lisboa, Portugal
    J Agric Food Chem 64:7452-7458. 2016
    ..StHR/CRKN) were evaluated, with and without the addition of the essential oils (EOs) of Satureja montana and Ruta graveolens...
  44. ncbi In vitro digestion, antioxidant and antiacetylcholinesterase activities of two species of Ruta: Ruta chalepensis and Ruta montana
    Ayda Khadhri
    a Faculty of Sciences, Unity of Research of Vegetal Ecology, University of El Manar II, Tunis, Tunisia
    Pharm Biol 55:101-107. 2017
    b>Ruta genus (Rutaceae) is abundantly used and described in the most ancient systematic records of medical practice of the Mediterranean world. In Tunisia, this genus is represented by two medicinal and aromatic shrubs: Ruta chalepensis L...
  45. pmc Insecticidal toxicities of carvacrol and thymol derived from Thymus vulgaris Lin. against Pochazia shantungensis Chou &Lu., newly recorded pest
    Jun Hwan Park
    Department of BioEnvironmental Chemistry, Chonbuk National University, Jeonju 54896, Korea
    Sci Rep 7:40902. 2017
    ..The LC50 values of Thymus vulgaris, Ruta graveolens, Citrus aurantium, Leptospermum petersonii and Achillea millefolium oils were recorded as 57.48, 84...
  46. ncbi Molluscicidal activity of some Moroccan medicinal plants
    M Hmamouchi
    Unité de recherche Substances Naturelles, Faculte de Medecine et de Pharmacie, Rabat, B P 6203, Rabat Institut, Maroc
    Fitoterapia 71:308-14. 2000
    ..activity, ethyl acetate extract from Origanum compactum and hexane extracts from both Chenopodium ambrosioides and Ruta chalepensis were the most active (LC(90)=2.00, 2.23 and 2...
  47. ncbi Antibacterial activity of extracts from some edible plants commonly consumed in Asia
    N S Alzoreky
    Faculty of Agriculture, Department of Food Science, Sana a University, Sana a, Yemen
    Int J Food Microbiol 80:223-30. 2003
    ..The most sensitive microorganism to extracts from Azadirachta indica, Cinnamomum cassia, Rumex nervosus, Ruta graveolens, Thymus serpyllum and Zingiber officinale was B. cereus, with MIC of 165 to 660 mg l(-1). E. coli and S...
  48. ncbi Field trials on the repellent activity of four plant products against mainly Mansonia population in western Ethiopia
    Mamuye Hadis
    Ethiopian Health and Nutrition Research Institute, PO Box 1242, Addis Ababa, Ethiopia
    Phytother Res 17:202-5. 2003
    The repellent activity of essential oils of lemon eucalyptus (Eucalyptus maculata citrodion), rue (Ruta chalepensis), oleoresin of pyrethrum (Chrysanthemum cinerariaefolium) and neem (Azadiracta indica) have been field tested as 40%, 50% ..
  49. ncbi Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase
    Marc Hehmann
    Institut fur Pharmazeutische Biologie, Philipps Universitat Marburg, Germany
    Eur J Biochem 271:932-40. 2004
    ..had been reported to methylate bergaptol to bergapten and xanthotoxol to xanthotoxin, from induced cell cultures of Ruta graveolens, Petroselinum crispum and Ammi majus...
  50. ncbi Specific accumulation and revised structures of acridone alkaloid glucosides in the tips of transformed roots of Ruta graveolens
    Inna Kuzovkina
    Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya ul 35, 127276 Moscow, Russia
    Phytochemistry 65:1095-100. 2004
    The root tips of Ruta graveolens (common rue) show strong autofluorescence of acridone alkaloids, which are characteristic secondary metabolites of this plant...
  51. ncbi Phytotoxins from the leaves of Ruta graveolens
    Amber L Hale
    Department of Pharmacognosy, University of Mississippi, University, Mississippi 38677, USA
    J Agric Food Chem 52:3345-9. 2004
    Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens (common rue) leaves led to the isolation of the furanocoumarins 5-methoxypsoralen (5-MOP), 8-methoxypsoralen (8-MOP), and the quinolone alkaloid graveoline as ..
  52. ncbi Dual role of boxB RNA motif in the mechanisms of termination/antitermination at the lambda tR1 terminator revealed in vivo
    Erwann Vieu
    Centre de Biophysique Moleculaire, CNRS, rue Charles Sadron, 45071 Orleans, France
    J Mol Biol 339:1077-87. 2004
    ..at the phage lambda tR1 terminator is governed primarily by the upstream rut element that encodes two RNA regions rutA and rutB...
  53. ncbi Antimicrobial and cytotoxic activity of Ruta graveolens
    A Ivanova
    Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria
    Fitoterapia 76:344-7. 2005
    The methanol, petroleum ether, ethyl acetate and water-methanol extracts of Ruta graveolens were found to possess antimicrobial and cytotoxic activities.
  54. ncbi [Transformation of the names of certain herbs by linguistic transfer - colchicum, wormseed, soybean, nandina and wijnruit]
    Masao Uchibayashi
    Yakushigaku Zasshi 39:350-4. 2004
    ..and soybeans, (4) from the Japanese plant nanten to the genus Nandina, and (5) from the Dutch term wijnruit (wine-ruta) to hen-ruda in Japanese...
  55. ncbi Neuropharmacological profile of an ethanol extract of Ruta chalepensis L. in mice
    M E Gonzalez-Trujano
    Direccion de Investigaciones en Neurociencias del Instituto Nacional de Psiquiatria Ramon de la Fuente, Calz Mexico Xochimilco 101, Col Sn Lorenzo Huipulco, 14370 Mexico, D F, Mexico
    J Ethnopharmacol 106:129-35. 2006
    The effects of an ethanol extract of the aerial parts of Ruta chalepensis on the central nervous system (CNS) and LD(50) determination were studied in mice...
  56. pmc A previously undescribed pathway for pyrimidine catabolism
    Kevin D Loh
    Department of Plant and Microbial Biology, 111 Koshland Hall, University of California, Berkeley, CA 94720 3102, USA
    Proc Natl Acad Sci U S A 103:5114-9. 2006
    ..We propose that the genes of this operon be named rutA-G for pyrimidine utilization...
  57. ncbi Fifth instar experience reduces aversiveness of the plant extract ruda (Ruta Graveolens) in the adult triatomine Rhodnius prolixus Stal 1859
    Charles I Abramson
    Laboratory of Comparative Psychology and Behavioral Biology, Department of Psychology, 215 N Murray, Stillwater, OK 74078, USA
    J Vector Ecol 31:196-7. 2006
  58. ncbi Anti-tumour activity of Ruta graveolens extract
    K C Preethi
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala 680555, India
    Asian Pac J Cancer Prev 7:439-43. 2006
    An extract of Ruta graveolens was found to be cytotoxic to Dalton's lymphoma ascites (DLA), Ehrlich ascites carcinoma (EAC) and L929 cells in culture (IC100=16 mg/ml) and also to increase the lifespan of tumour bearing animals...
  59. ncbi Combinatorial synthesis by nature: volatile organic sulfur-containing constituents of Ruta chalepensis L
    Sina Escher
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chem Biodivers 3:943-57. 2006
    ..new natural fragrance and flavor ingredients prompted us to examine a solvent extract of sulfurous-sweaty smelling Ruta chalepensis L. (Rutaceae) plant material more closely...
  60. ncbi The ecological aspect of ethnobotany and ethnopharmacology of population in Bosnia and Herzegovina
    Sulejman S Redzić
    Center of Ecology and Natural Resources, Faculty of Science University of Sarajevo, Sarajevo, Bosnia and Herzegovina
    Coll Antropol 31:869-90. 2007
    ..asclepiadea, Helichrysum italicum, Lycopodium clavatum, Marrubium vulgare, Nepeta cataria, Populus tremula, Ruta graveolens, Tamus communis, Teucrium montanum, T. chamaedrys, and endemic plants Gentiana lutea subsp...
  61. doi Methanolic extract of Ruta graveolens L. inhibits inflammation and oxidative stress in adjuvant induced model of arthritis in rats
    M Ratheesh
    Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram 695581, India
    Inflammopharmacology 17:100-5. 2009
    b>Ruta graveolens L. (Rutaceae) are traditionally used for the treatment of rheumatism, arthritis and other inflammatory conditions in the traditional medicine of India...
  62. ncbi The role of NO and cGMP in antispasmodic activity of Ruta chalepensis leaf extract on rat ileum
    A A Moazedi
    Department of Biology, School of Science, Shahid Chamran University, Ahwaz, Iran
    Pak J Biol Sci 13:83-7. 2010
    The aim of present study was to investigate the effect of hydroalcoholic extract of Ruta chalepensis (Rutaceae) leaves on rat ileum contractility and possible mechanism(s) involved...
  63. doi Evaluation of antileishmanial, cytotoxic and antioxidant activities of essential oils extracted from plants issued from the leishmaniasis-endemic region of Sned (Tunisia)
    S Ben Hadj Ahmed
    Departement de Biologie, Faculté des Sciences de Gafsa, Campus Universitaire Zarroug Gafsa 2112, Gafsa, Tunisia
    Nat Prod Res 25:1195-201. 2011
    ..62% and camphor at 13.82%) is significantly active against both L. major and L. infantum, whereas Ruta chalepensis EO (rich on 2-undecanone at 84.28%) is only active against L. infantum...
  64. doi A 2-oxoglutarate-dependent dioxygenase from Ruta graveolens L. exhibits p-coumaroyl CoA 2'-hydroxylase activity (C2'H): a missing step in the synthesis of umbelliferone in plants
    Guilhem Vialart
    UMR 1121 Lorraine University, INRA Agronomie et Environnement Nancy Colmar, ENSAIA, 2 Avenue de la Foret de Haye, 54505 Vandœuvre Lès Nancy, France
    Plant J 70:460-70. 2012
    ..approach and a cDNA library screen to identify an orthologous ORF (Genbank accession number JF799117) from Ruta graveolens L...
  65. pmc Antidiabetic and cytotoxicity screening of five medicinal plants used by traditional African health practitioners in the Nelson Mandela Metropole, South Africa
    Mea van Huyssteen
    Department of Pharmacy, Nelson Mandela Metropolitan University, Port Elizabeth, South Africa
    Afr J Tradit Complement Altern Med 8:150-8. 2011
    ..project with these practitioners focused on the screening of Bulbine frutescens, Ornithogalum longibracteatum, Ruta graveolens, Tarchonanthus camphoratus and Tulbaghia violacea for antidiabetic and cytotoxic potential...
  66. ncbi [Cloning, expression and functional identification of a type III polyketide synthase gene from Huperzia serrata]
    Jin cui Ye
    Institute of Materia Medica, Zhejiang Academy of Medical Sciences, Hangzhou, 310013, China
    Yao Xue Xue Bao 46:1273-8. 2011
    ..Interestingly, H. serrata PKS2 lacks most of the consensus active site sequences with acridone synthase from Ruta graveolens (Rutaceae).
  67. doi Iron deficiency and fatigue in adolescent females with heavy menstrual bleeding
    W Wang
    College of Medicine, The Ohio State University, Columbus, OH, USA
    Haemophilia 19:225-30. 2013
    ..To evaluate the degree and effects of menstrual blood loss, we utilized the Ruta Menorrhagia Severity Score. We investigated the symptoms of fatigue using the Fatigue Severity Scale...
  68. doi Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L
    Daycem Khlifi
    Universite de Toulouse, Laboratoire des Interactions Moleculaires et Reactivite Chimique et Photochimique, UMR CNRS 5623, Universite Paul Sabatier, 118 route de Narbonne, F 31062 Toulouse, France
    Food Chem Toxicol 55:202-8. 2013
    In this study, biological activities of methanolic extracts from Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L. plants, collected in Centre of Tunisia, were investigated...
  69. doi Bioactivity against Bursaphelenchus xylophilus: Nematotoxics from essential oils, essential oils fractions and decoction waters
    Jorge M S Faria
    Universidade de Lisboa, Faculdade de Ciencias de Lisboa, DBV, IBB, Centro de Biotecnologia Vegetal, C2, Campo Grande, 1749 016 Lisboa, Portugal
    Phytochemistry 94:220-8. 2013
    ..Twenty EOs showed corrected mortalities ⩾96% at 2 μL/mL. These were further tested at lower concentrations. Ruta graveolens, Satureja montana and Thymbra capitata EOs showed lethal concentrations (LC100)<0.4μL/mL...
  70. doi Oral administration of alkaloid fraction from Ruta graveolens inhibits oxidative stress and inflammation in hypercholesterolemic rabbits
    M Ratheesh
    Department of Biochemistry, University of Kerala, Thiruvananthapuram, India
    Pharm Biol 51:1552-8. 2013
    The anti-atherogenic effect of alkaloid fraction from Ruta graveolens Linn (Rutaceae) extract is suspected to be related to its activities of antioxidation and anti-inflammation.
  71. ncbi [Effects of ruta SSP on the activity of the smooth gastrointestinal muscle isolated of rat]
    Carlota A Grigorjev
    Cátedra de Farmacología General Escuela Práctica Facultad de Ciencias Médicas Universidad Nacional de Córdoba Santa Rosa 1085, 5000 Cordoba, Argentina
    Rev Fac Cien Med Univ Nac Cordoba 67:77-80. 2010
    b>Ruta graveolens L. and Ruta chalepensis L. are plants used in folkloric medicine as antispasmodics, digestive and for intestinal gases...
  72. pmc Antibacterial activity of methanol extract of Ruta chalapensis (L), Quercus infectoria (Oliver) and Canthium parviflorum (Lam)
    P Sathiya Priya
    Depart of Biochemistry, Karpagam University, Coimbatore, Tamilnadu, India
    Anc Sci Life 29:28-31. 2009
    The present study aimed at evaluating the antibacterial activity of methanol extract of Ruta chalapensis, L., (Rutaceae), Quercus infectoria Oliver., (Fagaceae) and Canthium parviflorum Lam...
  73. pmc A multi-faceted analysis of RutD reveals a novel family of α/β hydrolases
    Aleksandra A Knapik
    Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia 22903, USA
    Proteins 80:2359-68. 2012
    ..The rut operon in E. coli evaded detection until 2006, yet consists of seven proteins named RutA, RutB, etc. through RutG...
  74. pmc Up and down: stamen movements in Ruta graveolens (Rutaceae) enhance both outcrossing and delayed selfing
    Ming Xun Ren
    Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China
    Ann Bot 110:1017-25. 2012
    ..Recently, complex patterns of stamen movements have been identified in Loasaceae, Parnassiaceae, Rutaceae and Tropaeolaceae. In this study the stamen movements in Ruta graveolens (Rutaceae) and their impact on pollination are determined.
  75. ncbi Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures
    Renuka Diwan
    Department of Botany, University of Pune, India
    Nat Prod Commun 7:895-8. 2012
    ..furanocoumarin production was investigated by exogenous addition, at different concentrations, to shoot cultures of Ruta graveolens at different phases of growth...
  76. pmc CYP98A22, a phenolic ester 3'-hydroxylase specialized in the synthesis of chlorogenic acid, as a new tool for enhancing the furanocoumarin concentration in Ruta graveolens
    Fazeelat Karamat
    Université de Lorraine UMR 1121, Agronomie et Environnement Nancy Colmar, ENSAIA 2 avenue de la forêt de Haye, 54505 Vandœuvre Lès Nancy, France
    BMC Plant Biol 12:152. 2012
    ..with proven therapeutic properties and are produced in only a small number of medicinal plant species such as Ruta graveolens. In vivo, these molecules play a protective role against phytophageous insect attack...
  77. ncbi From traditional European medicine to discovery of new drug candidates for the treatment of dementia and Alzheimer's disease: acetylcholinesterase inhibitors
    P Russo
    Laboratory of Systems Approaches and Non Communicable Diseases, IRCCS San Raffaele Pisana, Via di Valcannuta, 247, I 00166 Roma, Italia
    Curr Med Chem 20:976-83. 2013
    ..Starting from Galanthamine, properties of Melissa species, Salvia officinalis, Arnica chamissonis and Ruta graveolens are discussed to point to the role of these plants as potential sources for the development of ..
  78. doi Larvicidal and repellent activity of essential oils from wild and cultivated Ruta chalepensis L. (Rutaceae) against Aedes albopictus Skuse (Diptera: Culicidae), an arbovirus vector
    Barbara Conti
    Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124, Pisa, Italy
    Parasitol Res 112:991-9. 2013
    ..In our research, the essential oils extracted from fresh leaves of wild and cultivated plants of Ruta chalepensis L...
  79. doi Acoustic excitations in glassy sorbitol and their relation with the fragility and the boson peak
    B Ruta
    European Synchrotron Radiation Facility, BP220, F 38043 Grenoble, France
    J Chem Phys 137:214502. 2012
    ..b>Ruta, G. Monaco, F. Scarponi, and D. Fioretto, Philos. Mag. 88, 3939 (2008)]...
  80. doi Anti-inflammatory effect of quinoline alkaloid skimmianine isolated from Ruta graveolens L
    M Ratheesh
    Department of Biochemistry, Kerala University, Trivandrum, India
    Inflamm Res 62:367-76. 2013
    The present study evaluates the anti-inflammatory effect of the quinoline alkaloid skimmianine (SKM), isolated from Ruta graveolens L., against carrageenan-induced acute inflammation.
  81. doi Chemical composition and antimicrobial activity of the essential oils from four Ruta species growing in Algeria
    Farah Haddouchi
    Laboratory of Natural Products, Department of Biology, Faculty of Sciences, Abou Bekr Belkaid University, B P 119, Tlemcen 13000, Algeria
    Food Chem 141:253-8. 2013
    ..of this research is to study the antibacterial and antifungal effects of four traditional plants essential oils, Ruta angustifolia, Ruta chalepensis, Ruta graveolens and Ruta tuberculata, against standard bacterial and fungal strains...
  82. ncbi A new furoquinoline alkaloid with antifungal activity from the leaves of Ruta chalepensis L
    A Emam
    Department of Biochemistry, Faculty of Agriculture, Fayoum University, Fayoum, Egypt
    Drug Discov Ther 4:399-404. 2010
    ..known biscoumarin daphnoretin (2) as the active constituents of the chloroform extract obtained from the leaves of Ruta chalepensis...
  83. ncbi Mutagenicity testing of rutacridone epoxide and rutacridone, alkaloids in Ruta graveolens L., using the Salmonella/microsome assay
    H Paulini
    Institut fúr Botanik und Pharmazeutische Biologie der Universität Erlangen Nürnberg, FRG
    Mutagenesis 4:45-50. 1989
    ..Evidence is presented that rutacridone is metabolized by rat liver enzymes to the corresponding epoxide as the ultimate mutagen...
  84. ncbi Perinatal toxicology of Ruta chalepensis (Rutaceae) in mice
    R Zeichen de Sa
    Departamento de Farmacologia, Instituto Nacional de Medicamentos, Administración Nacional de Medicamentos, Alimentos y Tecnología Médica, Buenos Aires, Argentina
    J Ethnopharmacol 69:93-8. 2000
    Dried leaf infusions of Ruta chalepensis L. (Rutaceae), 'rue', 'ruda', were found to cause perinatal changes in mice, at daily doses of 0.16, 0.80 and 1.60 g/kg, administered p.o. from 1 to 14 days post coitum...
  85. ncbi High-resolution gas-chromatographic analysis of the secondary metabolites obtained by subcritical-fluid extraction from Colombian rue (Ruta graveolens L.)
    E E Stashenko
    Phytochemistry and Chromatography Laboratory, School of Chemistry, Industrial University of Santander, A A 678, Bucaramanga, Colombia
    J Biochem Biophys Methods 43:379-90. 2000
    ..Extractor, was used to isolate secondary metabolites from leaves, flowers, stems and roots of Colombian rue (Ruta graveolens L.)...
  86. ncbi Intracranial cysticercosis: an effective treatment with alternative medicines
    P Banerji
    PBH Research Foundation, 10 3 1 Elgin Road, Calcutta 700 020, West Bengal, India
    In Vivo 15:181-4. 2001
    The purpose of this study was to demonstrate the cysticidal activities of Ruta graveolens and calcium phosphate in fractional dilutions as a completely new approach for the treatment of neurocysticercosis in humans...
  87. ncbi Water-soluble glycosides from Ruta graveolens
    C C Chen
    National Research Institute of Chinese Medicine, NO 155 1, Sec 2, Li Nung Street, Peitou, Taipei, Taiwan, Republic of China
    J Nat Prod 64:990-2. 2001
    An EtOH extract of the dried aerial parts of Ruta graveolens was suspended in water and then partitioned with EtOAc...
  88. ncbi Biological effects of rutin on the survival of Escherichia coli AB1157 and on the electrophoretic mobility of plasmid PUC 9.1 DNA
    Luciana C Bernardo
    Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcantara Gomes, Departamento de Biofisica e Biometria, RJ, Brazil
    Cell Mol Biol (Noisy-le-grand) 48:517-20. 2002
    The use of natural products as medicines is growing in the world. The rutin, a compound isolated from Ruta graveolens, is a flavonoid, which has been suggested to have antioxidant properties and to reduce the triacylglycerol levels...
  89. ncbi Potential allelochemicals from the essential oil of Ruta graveolens
    Vincenzo De Feo
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, I 84084 Salerno, Fisciano, Italy
    Phytochemistry 61:573-8. 2002
    The essential oil of aerial parts of Ruta graveolens was obtained by hydrodistillation with a 0.74% yield on a dry weight basis. Thirty-eight components were identified by GC and GC-MS analyses...
  90. ncbi A new dicoumarinyl ether and two rare furocoumarins from Ruta montana
    Z Kabouche
    Université Mentouri Constantine, Faculte des Sciences, Laboratoire d Obtention de Substances Thérapeutiques L O S T, Campus Chaabet Ersas, Constantine 25000, Algerie
    Fitoterapia 74:194-6. 2003
    A new dicoumarinyl ether, rutamontine and two rare furocoumarins, heraclenol and isopimpinellin, were isolated from Ruta montana...
  91. ncbi Conjugate additions of o-iodoanilines and methyl anthranilates to acetylenic sulfones. A new route to quinolones including first syntheses of two alkaloids from the medicinal herb Ruta chalepensis
    Thomas G Back
    Department of Chemistry, University of Calgary, Calgary, Alberta, Canada T2N 1N4
    J Org Chem 68:2223-33. 2003
    ..The resulting 2-substituted 4-quinolones included the naturally occurring medicinal compounds 1 and 2 and the O-methyl derivative 3...
  92. ncbi Evaluating companion planting and non-host masking odors for protecting roses from the Japanese beetle (Coleoptera: Scarabaeidae)
    D W Held
    Department of Entomology, University of Kentucky, Lexington, KY 40546 0091, USA
    J Econ Entomol 96:81-7. 2003
    ..Three reputedly effective companion species, rue (Ruta graveolens L.), zonal geranium (Pelargonium x hortorum Bailey), and garlic chives (Allium scheonparum L...
  93. ncbi Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer
    Sen Pathak
    Department of Molecular Genetics, M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Oncol 23:975-82. 2003
    ..We investigated the brain cancer cell-killing activity of a homeopathic medicine, Ruta, isolated from a plant, Ruta graveolens...
  94. ncbi Protection against murine endotoxemia by treatment with Ruta chalepensis L., a plant with anti-inflammatory properties
    Liliana Iauk
    Department of Microbiological and Gynaecological Sciences, Section of Microbiology, University of Catania, Via Androne 81, Catania 95124, Italy
    J Ethnopharmacol 90:267-72. 2004
    The anti-inflammatory effect of the extract of Ruta Chalepensis L. (Rutaceae) on the course of lethal endotoxemia in BALB/c mice was studied. When administered by gavage as 1 g/kg per day starting 14 or 7 days prior to injection of 0...
  95. ncbi A new coumarin glucoside, coumarins and alkaloids from Ruta corsica roots
    Cedric Bertrand
    Laboratoire Pharmacophores Redox, Phytochimie et Radiobiologie, EA 3030 Faculté des Sciences Pharmaceutiques, Université Paul Sabatier 35, chemin des Maraichers, 310362 Toulouse 4, France
    Fitoterapia 75:242-4. 2004
    ..one coumarin, five furanocoumarins, three bicoumarins, three quinoline alkaloids and one sinapoyl sucrose derivative have been isolated from the roots of Ruta corsica.
  96. ncbi Accumulation of biologically active furanocoumarins in Ruta graveolens ssp. divaricata (Tenore) Gams in vitro culture
    H Ekiert
    Department of Pharmaceutical Botany, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Pharmazie 60:66-8. 2005
    ..dynamics of accumulation of five linear furanocoumarins and umbelliferone in stationary liquid cultures of Ruta graveolens ssp. divaricata (Tenore) Gams during 6-week growth cycles...
  97. ncbi Accumulation of biologically active furanocoumarins in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams
    H Ekiert
    Chair and Department of Pharmaceutical Botany, Collegium Medicum, Jagiellonian University, 9 Medyczna Street, 30 688 Krakow, Poland
    Pharmazie 60:623-6. 2005
    ..xanthotoxin, isopimpinellin, imperatorin) and their biogenetic precursor, umbelliferone, in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams during 6-week growth cycles...
  98. ncbi Temporary uterine artery occlusion for treatment of menorrhagia and uterine fibroids using an incisionless Doppler-guided transvaginal clamp: case report
    G A Vilos
    Department of Obstetrics and Gynecology, University of Western Ontario, St Joseph s Health Care, London, Ontario, Canada
    Hum Reprod 21:269-71. 2006
    ..Menorrhagia symptoms were tracked with the Ruta Menorrhagia Severity Scale. Uterine and fibroid volumes were measured by analysis of magnetic resonance images...
  99. ncbi Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs
    Kumudini M Meepagala
    USDA ARS, Natural Products Utilization Research Unit, P O Box 8048, University, MS 38677, USA
    Phytochemistry 66:2689-95. 2005
    Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens roots yielded rutacridone epoxide with potent selective algicidal activity towards the 2-methyl-isoborneol (MIB)-producing blue-green alga Oscillatoria ..
  100. ncbi Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity
    Anne Adsersen
    Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2 Universitetsparken, 2100 Copenhagen O, Denmark
    J Ethnopharmacol 104:418-22. 2006
    ..laxa and Corydalis solida ssp. slivenensis. Extracts of Ruta graveolens, Lavandula angustifolia, Rosmarinus officinalis, Petroselinum crispum and Mentha spicata exhibited ..
  101. ncbi Antiandrogenic activity of Ruta graveolens L in male Albino rats with emphasis on sexual and aggressive behavior
    Nabil Azar Khouri
    Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
    Neuro Endocrinol Lett 26:823-9. 2005
    The Ruta graveolens L. is currently used by the Jordanian population systemically for its antispasmodic, diuretic, sedative, and analgesic effects and externally for its antirheumatic effect.

Research Grants3

  1. GENETIC STUDIES OF GLUTAMINE SYNTHETASE IN BACTERIA
    SYDNEY GOVONS KUSTU; Fiscal Year: 2010
    ..and biochemical approaches to identify the intermediates of the Rut pathway and the enzymatic activities of the RutA-RutF proteins. We will study the DNA binding and transcriptional repression activities of RutR in vitro...
  2. Small Molecule Kv1.3 Blockers as New Therapeutics for Multiple Sclerosis
    Heike Wulff; Fiscal Year: 2007
    ..Following up on anecdotal reports from the late 1980s that tea prepared from Ruta graveolens, the common rue, had beneficial effects in MS, we discovered that Ruta contained a small molecule called ..
  3. Structural Analysis of Voltage-gated Potassium Channels
    ROBERT BLAUSTEIN; Fiscal Year: 2006
    ..abstract_text> ..