domestic silkworm

Summary

Alias: silk moth, silkworm, Bombyx mori, Bombyx mori Linnaeus, 1758

Top Publications

  1. pmc Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori
    Shogo Atsumi
    Division of Insect Sciences, National Institute of Agrobiological Sciences, Tsukuba 305 8634, Japan
    Proc Natl Acad Sci U S A 109:E1591-8. 2012
  2. pmc Transcriptional regulation of juvenile hormone-mediated induction of Krüppel homolog 1, a repressor of insect metamorphosis
    Takumi Kayukawa
    Division of Insect Sciences, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8634, Japan
    Proc Natl Acad Sci U S A 109:11729-34. 2012
  3. ncbi Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio
    S Inoue
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 1 1 Tsutsumidori Amamiyamachi, Aoba ku, Sendai 981 8555 Japan
    J Biol Chem 275:40517-28. 2000
  4. ncbi A draft sequence for the genome of the domesticated silkworm (Bombyx mori)
    Qingyou Xia
    Southwest Agricultural University, Chongqing Beibei, 400716, China
    Science 306:1937-40. 2004
  5. ncbi Characterization of a novel silkworm (Bombyx mori) phenol UDP-glucosyltransferase
    Teresa Luque
    Department of Biology, Imperial College of Science, Technology and Medicine, London SW7 2AZ, UK
    Eur J Biochem 269:819-25. 2002
  6. ncbi CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila
    Ryusuke Niwa
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, USA
    J Biol Chem 279:35942-9. 2004
  7. ncbi Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis
    James T Warren
    Department of Biology, University of North Carolina, 342 Wilson Hall, CB 3280, Chapel Hill, NC 27599 3280, USA
    Insect Biochem Mol Biol 34:991-1010. 2004
  8. ncbi Cloning and characterization of the pheromone biosynthesis activating neuropeptide receptor from the silkmoth, Bombyx mori. Significance of the carboxyl terminus in receptor internalization
    J Joe Hull
    Molecular Entomology Laboratory, RIKEN The Institute of Physical and Chemical Research, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    J Biol Chem 279:51500-7. 2004
  9. doi Functional characterization of the Bombyx mori fatty acid transport protein (BmFATP) within the silkmoth pheromone gland
    Atsushi Ohnishi
    Molecular Entomology Laboratory, Advanced Science Institute, RIKEN, Wako, Saitama 351 0198, Japan
    J Biol Chem 284:5128-36. 2009
  10. ncbi Isolation and characterization of a Bombyx vasa-like gene
    H Nakao
    Department of Insect Genetics and Breeding, National Institute of Sericultural and Entomological Science, 1 2 Oowashi, Tsukuba 305 8634, Japan
    Dev Genes Evol 209:312-6. 1999

Research Grants

  1. Convergent Molecular Evolution of Moth and Spider Silks
    NADIA AYOUB; Fiscal Year: 2009
  2. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald L Jarvis; Fiscal Year: 2010
  3. SILK SCAFFOLDS FOR BONE FORMATION
    David Kaplan; Fiscal Year: 2003
  4. Circadian Clock: Differential Cryptochrome Functions
    Steven M Reppert; Fiscal Year: 2011
  5. Peijing Jeremy Wang; Fiscal Year: 2016
  6. Yohei Kirino; Fiscal Year: 2016
  7. Recombinant Subunit Protein for Flu Vaccine
    Carolyn Weeks Levy; Fiscal Year: 2006
  8. CONTROL OF TRNA GENE EXPRESSION IN BOMBYX MORI
    KAREN SPRAGUE; Fiscal Year: 1993
  9. MULTIGENE FAMILIES: STRUCTURE, EXPRESSION AND EVOLUTION
    Thomas Eickbush; Fiscal Year: 1991
  10. REGULATION OF AMINOACYL-TRNA SYNTHETASES IN BOMBYX
    DAVID DIGNAM; Fiscal Year: 1990

Patents

  1. HYBRID SILK AND METHOD OF PRODUCING THE SAME
  2. COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS
  3. Novel Gene Specifically Expressed in the Posterior Silk Gland and Promoter Therof
  4. Fibroin Heavy chain Core Promoter of Bombyx mori and the Vector Thereof
  5. binary gene expression system
  6. Juvenile hormone sensor
  7. Nucleic acids sequence of a cell death-inducible vector, and the transgenic silkmoth strains carrying the DNA fragment inducing tissue-specific cell death
  8. Nucleic acids sequence of a cell death-inducible vector, and the transgenic silkmoth strains carrying the DNA fragment inducing tissue-specific cell death
  9. female lethal strain of Bombyx mori
  10. female lethal strain of Bombyx mori

Detail Information

Publications352 found, 100 shown here

  1. pmc Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori
    Shogo Atsumi
    Division of Insect Sciences, National Institute of Agrobiological Sciences, Tsukuba 305 8634, Japan
    Proc Natl Acad Sci U S A 109:E1591-8. 2012
    ..By using Bombyx mori as a model, we identified a candidate gene for a recessive form of resistance to Cry1Ab toxin on chromosome 15 ..
  2. pmc Transcriptional regulation of juvenile hormone-mediated induction of Krüppel homolog 1, a repressor of insect metamorphosis
    Takumi Kayukawa
    Division of Insect Sciences, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8634, Japan
    Proc Natl Acad Sci U S A 109:11729-34. 2012
    ..of Kr-h1 induction, we first cloned cDNAs encoding Kr-h1 (BmKr-h1) and Met (BmMet1 and BmMet2) homologs from Bombyx mori. In a B. mori cell line, BmKr-h1 was rapidly induced by subnanomolar levels of natural JHs...
  3. ncbi Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio
    S Inoue
    Laboratory of Molecular Biology, Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, 1 1 Tsutsumidori Amamiyamachi, Aoba ku, Sendai 981 8555 Japan
    J Biol Chem 275:40517-28. 2000
    Silk fibroin produced by the silkworm Bombyx mori consists of a heavy chain, a light chain, and a glycoprotein, P25...
  4. ncbi A draft sequence for the genome of the domesticated silkworm (Bombyx mori)
    Qingyou Xia
    Southwest Agricultural University, Chongqing Beibei, 400716, China
    Science 306:1937-40. 2004
    We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori), covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which exceeds the 13,379 genes reported for Drosophila melanogaster...
  5. ncbi Characterization of a novel silkworm (Bombyx mori) phenol UDP-glucosyltransferase
    Teresa Luque
    Department of Biology, Imperial College of Science, Technology and Medicine, London SW7 2AZ, UK
    Eur J Biochem 269:819-25. 2002
    ..molecular cloning and functional characterization of a phenol UDP-glucosyltransferase (UGT) from the silkworm, Bombyx mori, which was named BmUGT1. The complete cDNA clone is 1...
  6. ncbi CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila
    Ryusuke Niwa
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, USA
    J Biol Chem 279:35942-9. 2004
    ..P450 gene, designated Cyp306a1, that is essential for ecdysteroid biosynthesis in the PGs of the silkworm Bombyx mori and fruit fly Drosophila melanogaster...
  7. ncbi Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis
    James T Warren
    Department of Biology, University of North Carolina, 342 Wilson Hall, CB 3280, Chapel Hill, NC 27599 3280, USA
    Insect Biochem Mol Biol 34:991-1010. 2004
    ..gene identification has also resulted in the characterization of the corresponding 25-hydroxylase gene in Bombyx mori. Confirmation of 2,22,25-trideoxyecdysone (3beta,5beta-ketodiol) conversion to 2,22-dideoxyecdysone (3beta,..
  8. ncbi Cloning and characterization of the pheromone biosynthesis activating neuropeptide receptor from the silkmoth, Bombyx mori. Significance of the carboxyl terminus in receptor internalization
    J Joe Hull
    Molecular Entomology Laboratory, RIKEN The Institute of Physical and Chemical Research, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    J Biol Chem 279:51500-7. 2004
    ..a full-length 2780-nucleotide clone encoding a 46-kDa G protein-coupled receptor was amplified from a Bombyx mori pheromone gland cDNA library...
  9. doi Functional characterization of the Bombyx mori fatty acid transport protein (BmFATP) within the silkmoth pheromone gland
    Atsushi Ohnishi
    Molecular Entomology Laboratory, Advanced Science Institute, RIKEN, Wako, Saitama 351 0198, Japan
    J Biol Chem 284:5128-36. 2009
    ..By exploiting this unique system in the PG of the silkmoth, Bombyx mori, we found that BmFATP is predominantly expressed in the PG and undergoes up-regulation 1 day prior to eclosion...
  10. ncbi Isolation and characterization of a Bombyx vasa-like gene
    H Nakao
    Department of Insect Genetics and Breeding, National Institute of Sericultural and Entomological Science, 1 2 Oowashi, Tsukuba 305 8634, Japan
    Dev Genes Evol 209:312-6. 1999
    AcDNA for a vasa-like gene (BmVLG) was isolated from Bombyx mori. As with vasa in Drosophila, the expression is restricted to the germline in the larval (and pupal and adult?) stage, and the maternal transcript exists...
  11. doi Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body
    Yan Liu
    Key Laboratory of Insect Developmental Biology and Evolution, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    J Insect Physiol 56:1436-44. 2010
    ..From the silkworm, Bombyx mori, we have identified and characterized several key genes involved in the IIS pathway, including InR, IRS, ..
  12. doi Positional cloning of silkworm white egg 2 (w-2) locus shows functional conservation and diversification of ABC transporters for pigmentation in insects
    Ken Ichiro Tatematsu
    National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8634, Japan
    Genes Cells 16:331-42. 2011
    ..The white egg 2 (w-2) mutant of the silkworm, Bombyx mori, has white eggs and eyes because of lack of ommochrome granules in the serosa and eyes...
  13. doi Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori
    Shi Hong Gu
    Department of Zoology, National Museum of Natural Science, 1 Kuan Chien Road, Taichung 404, Taiwan, ROC
    Insect Biochem Mol Biol 41:197-202. 2011
    ..and tyrosine kinase are involved in PTTH-stimulated ecdysteroidogenesis by the prothoracic glands of both Bombyx mori and Manduca sexta...
  14. doi Identification of specific sites in the third intracellular loop and carboxyl terminus of the Bombyx mori pheromone biosynthesis activating neuropeptide receptor crucial for ligand-induced internalization
    J J Hull
    Molecular Entomology Laboratory, RIKEN Advanced Science Institute, Wako, Saitama, Japan
    Insect Mol Biol 20:801-11. 2011
    ..Using fluorescent Bombyx mori PBANR (BmPBANR) chimeras to study PBANR regulation, we previously showed that BmPBANR undergoes rapid ligand-..
  15. pmc Beta-fructofuranosidase genes of the silkworm, Bombyx mori: insights into enzymatic adaptation of B. mori to toxic alkaloids in mulberry latex
    Takaaki Daimon
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo, Japan
    J Biol Chem 283:15271-9. 2008
    ..Although these compounds do not harm the silkworm, Bombyx mori, a mulberry specialist, they are highly toxic to insects that do not normally feed on mulberry leaves...
  16. ncbi Control of juvenile hormone biosynthesis in Bombyx mori: cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata
    Terunori Kinjoh
    Faculty of Agriculture and Life Sciences, Hirosaki University, Hirosaki 036 8561, Japan
    Insect Biochem Mol Biol 37:808-18. 2007
    ..of all enzymes involved in the mevalonate pathway portion of the juvenile hormone (JH) biosynthetic pathway in Bombyx mori, i.e., those responsible for the formation of farnesyl diphosphate from acetyl-CoA...
  17. doi Non-molting glossy/shroud encodes a short-chain dehydrogenase/reductase that functions in the 'Black Box' of the ecdysteroid biosynthesis pathway
    Ryusuke Niwa
    Graduate School of Life and Environmental Sciences, University of Tsukuba, Tennoudai 1 1 1, Tsukuba, Ibaraki 305 8572, Japan
    Development 137:1991-9. 2010
    ..This gene was first isolated by positional cloning of the nm-g mutant of the silkworm Bombyx mori, which exhibits a low ecdysteroid titer and consequently causes a larval arrest phenotype...
  18. pmc Carotenoid silk coloration is controlled by a carotenoid-binding protein, a product of the Yellow blood gene
    Takashi Sakudoh
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, Japan
    Proc Natl Acad Sci U S A 104:8941-6. 2007
    ..The Y (Yellow blood) gene, a critical cocoon color determinant in the silkworm Bombyx mori, controls the uptake of carotenoids into the intestinal mucosa and the silk gland...
  19. pmc Repression of tyrosine hydroxylase is responsible for the sex-linked chocolate mutation of the silkworm, Bombyx mori
    Chun Liu
    Key Sericultural Laboratory of Agricultural Ministry, Institute of Sericulture and Systems Biology, Southwest University, Chongqing 400716, China
    Proc Natl Acad Sci U S A 107:12980-5. 2010
    ..Wild-type neonatal larvae of the silkworm, Bombyx mori, are completely black...
  20. ncbi Cytochrome P450 CYP307A1/Spook: a regulator for ecdysone synthesis in insects
    Toshiki Namiki
    Department of Integrated Biosciences, Rm 201, Graduate School of Frontier Sciences, The University of Tokyo, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, Japan
    Biochem Biophys Res Commun 337:367-74. 2005
    ..To identify genes functioning in the PG of the silkworm, Bombyx mori, we used differential display PCR and focused on a cytochrome P450 gene designated Cyp307a1...
  21. pmc Positional cloning of a Bombyx wingless locus flugellos (fl) reveals a crucial role for fringe that is specific for wing morphogenesis
    Kaoru Sato
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Bioscience Building 501, 5 1 5 Kashiwanoha, Kashiwa, Chiba 277 8562, Japan
    Genetics 179:875-85. 2008
    Mutations at the flügellos (fl) locus in Bombyx mori produce wingless pupae and moths because of the repressed response of wing discs to ecdysteroid. Four recessive fl alleles occurred spontaneously and were mapped at 13...
  22. ncbi Purification and molecular cloning of chemosensory proteins from Bombyx mori
    J F Picimbon
    Institut fur Physiologie, Universitat Hohenheim, Stuttgart, Germany
    Arch Insect Biochem Physiol 44:120-9. 2000
    ..From the antennae of Bombyx mori, we have purified and sequenced a protein (BmorCSP1) bearing sequence similarity to a class of soluble ..
  23. pmc Involvement of a bifunctional fatty-acyl desaturase in the biosynthesis of the silkmoth, Bombyx mori, sex pheromone
    Ken ichi Moto
    RIKEN, Hirosawa 2 1, Wako, Saitama 351 0198, Japan
    Proc Natl Acad Sci U S A 101:8631-6. 2004
    ..three cDNAs encoding desaturase family members from the pheromone gland of the inbred strain of the silkmoth, Bombyx mori. Transcript analyses by RT-PCR and subsequent functional assays using a Bac-to-Bac baculovirus expression ..
  24. ncbi Cloning, expression and characterization of theta-class glutathione S-transferase from the silkworm, Bombyx mori
    Kohji Yamamoto
    Laboratory of Insect Genetic Resources, Faculty of Agriculture, Kyushu University, 6 10 1 Hakozaki, Higashi ku, Fukuoka, Fukuoka 812 8581, Japan
    Comp Biochem Physiol B Biochem Mol Biol 141:340-6. 2005
    This study focused on glutathione S-transferase (GST), one of the detoxification enzymes, from the silkworm, Bombyx mori (GSTT1)...
  25. ncbi The molecular mechanism of the termination of insect diapause, part 1: A timer protein, TIME-EA4, in the diapause eggs of the silkworm Bombyx mori is a metallo-glycoprotein
    Minoru Isobe
    Laboratory of Organic Chemistry Graduate School of Bioagricultural Sciences, Nagoya University Chikusa, Nagoya 464 8601, Japan
    Chembiochem 7:1590-8. 2006
    ..ATPase that measures time intervals, functioning as a diapause duration clock in diapause eggs of the silkworm, Bombyx mori. Characterization of the primary and higher structures of the TIME-EA4 would be desirable to clarify the ..
  26. pmc ERK- and JNK-dependent signaling pathways contribute to Bombyx mori nucleopolyhedrovirus infection
    Susumu Katsuma
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Virol 81:13700-9. 2007
    ..intracellular signaling pathways induced by baculovirus infection, we examined the involvement of MAPKs in Bombyx mori nucleopolyhedrovirus (BmNPV) infection of BmN cells...
  27. doi Molecular cloning and characterization of cDNAs encoding dopamine receptor-1 and -2 from brain-suboesophageal ganglion of the silkworm, Bombyx mori
    K Mitsumasu
    Sericulture and Entomoresources, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya, Aichi, Japan
    Insect Mol Biol 17:185-95. 2008
    ..between dopamine and the release of diapause hormone into the blood, we cloned and characterized cDNAs encoding Bombyx mori dopamine receptor-1 and -2 (BmDopR1 and 2) from the pupal brain-suboesophageal ganglion...
  28. doi Biochemical properties of an omega-class glutathione S-transferase of the silkmoth, Bombyx mori
    Kohji Yamamoto
    Institute of Genetic Resources, Faculty of Agriculture, Kyushu University Graduate School, Higashi ku, Fukuoka 812 8581, Japan
    Comp Biochem Physiol C Toxicol Pharmacol 149:461-7. 2009
    A cDNA encoding an omega-class glutathione S-transferase of the silkmoth, Bombyx mori (bmGSTO), was cloned by reverse transcriptase-polymerase chain reaction...
  29. pmc The silkworm mutant lemon (lemon lethal) is a potential insect model for human sepiapterin reductase deficiency
    Yan Meng
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    J Biol Chem 284:11698-705. 2009
    ..strains, lemon (lem) and its lethal allele lemon lethal (lem(1)) with yellow body coloration, of the silkworm Bombyx mori could be used as the first insect model for human SPR deficiency diseases...
  30. ncbi Identification, genomic organization and expression pattern of glutathione S-transferase in the silkworm, Bombyx mori
    Quanyou Yu
    The Key Sericultural Laboratory of Agricultural Ministry, College of Biotechnology, Southwest University, Chongqing, China
    Insect Biochem Mol Biol 38:1158-64. 2008
    ..We have identified 23 putative cytosolic GSTs by searching the new assembly of the Bombyx mori genome sequence. Phylogenetic analyses on the amino acid sequences reveal that 21 of the B...
  31. doi betaFTZ-F1 and Broad-Complex positively regulate the transcription of the wing cuticle protein gene, BMWCP5, in wing discs of Bombyx mori
    Hua Bing Wang
    Faculty of Agriculture, Utsunomiya University, 350 Mine, Utsunomiya, Tochigi 321 8505, Japan
    Insect Biochem Mol Biol 39:624-33. 2009
    ..Expression of BMWCP5 was strong at around pupation and weak at the mid-pupal stage in wing tissues of Bombyx mori. We analyzed the upstream region of the BMWCP5 gene using a transient reporter assay with a gene gun system to ..
  32. pmc Annotation and expression of carboxylesterases in the silkworm, Bombyx mori
    Quan You Yu
    The Institute of Agricultural and Life Sciences, Chongqing University, Chongqing 400044, China
    BMC Genomics 10:553. 2009
    ..However, genome-wide characterization of COEs in phytophagous insects and comparative analysis remain to be performed...
  33. doi Two Tor genes in the silkworm Bombyx mori
    S Zhou
    Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Insect Mol Biol 19:727-35. 2010
    ..Tor genes, BmTor1 and BmTor2, were identified as a pair of inverted repeats in the genome of the silkworm Bombyx mori. The synteny of BmTor1 and CG8360 indicates that BmTor1 is the orthologue while BmTor2 is a duplicate...
  34. doi Effect of RNAi-mediated knockdown of the Bombyx mori transformer-2 gene on the sex-specific splicing of Bmdsx pre-mRNA
    Masataka G Suzuki
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan
    Int J Dev Biol 56:693-9. 2012
    ..The function of Bmtra-2, the Bombyx mori homolog of tra-2, on the other hand remains to be elucidated...
  35. doi Ras1CA-upregulated BCPI inhibits cathepsin activity to prevent tissue destruction of the Bombyx posterior silk gland
    Li Ma
    Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    J Proteome Res 12:1924-34. 2013
    Using the GAL4/UAS transgenic system established in the silkworm, Bombyx mori, we have previously reported that overexpression of the Ras1(CA) oncogene specifically in the posterior silk gland (PSG) resulted in improved fibroin synthesis,..
  36. pmc Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori
    Azusa Sato
    Faculty of Textile Science and Technology, Shinshu University, Ueda 386 8567, Japan
    Proc Natl Acad Sci U S A 111:E1249-55. 2014
    In the bivoltine strain of the silkworm, Bombyx mori, embryonic diapause is induced transgenerationally as a maternal effect...
  37. ncbi Complete nucleotide sequences of major plasma protein genes of Bombyx mori
    S Mori
    Department of Biology, Tokyo Metropolitan University, Japan
    Biochim Biophys Acta 1090:129-32. 1991
    In the silkworm, Bombyx mori, a family of hormone-sensitive genes encodes major plasma proteins, termed '30K proteins'...
  38. ncbi cDNA cloning of acyl-CoA desaturase homologs in the silkworm, Bombyx mori
    T Yoshiga
    Laboratory of Molecular Entomology and Baculovirology, RIKEN, Hirosawa 2 1, Wako, Saitama, Japan
    Gene 246:339-45. 2000
    ..desaturase clones from a pheromone gland cDNA library by using the EST (expressed sequence tag) database of Bombyx mori. The putative acyl-CoA desaturases encoded by the clones desat 1 (2029bp) and desat 2 (2341bp) have 98% ..
  39. ncbi Characterization of acyl-CoA-binding protein (ACBP) in the pheromone gland of the silkworm, Bombyx mori
    S Matsumoto
    The Institute of Physical and Chemical Research RIKEN, Hirosawa 2 1, Wako Shi, Saitama 351 0198, Japan
    Insect Biochem Mol Biol 31:603-9. 2001
    ..We have purified a 10-kDa protein from the cytosolic fraction of Bombyx mori pheromone glands by using affinity chromatography with a palmitoyl-CoA-agarose column and reversed-phase HPLC...
  40. ncbi cDNA cloning of calcineurin heterosubunits from the pheromone gland of the silkmoth, Bombyx mori
    T Yoshiga
    Laboratory of Molecular Entomology and Baculovirology, The Institute of Physical and Chemical Research RIKEN, Hirosawa 2 1, Wako Shi, 351 0198, Saitama, Japan
    Insect Biochem Mol Biol 32:477-86. 2002
    ..PBAN) stimulates the step of fatty acyl reduction in the pheromone biosynthetic pathway of the silkmoth, Bombyx mori. It has been suggested that the intracellular signal transduction of PBAN in B...
  41. ncbi Alternative splicing of the primary transcript generates heterogeneity within the products of the gene for Bombyx mori chitinase
    Babiker M A Abdel-Banat
    Laboratory of Biochemistry, Department of Biological Science, Faculty of Agriculture, Yamaguchi University, Yamaguchi 753 8515, Japan
    J Biol Chem 277:30524-34. 2002
    The gene of chitinase in the silkworm, Bombyx mori, generates four mRNA products by alternative splicing...
  42. ncbi Molecular cloning and characterization of the translationally controlled tumor protein gene in Bombyx mori
    Jae Man Lee
    Laboratory of Silkworm Science, Faculty of Agriculture, Kyushu University Graduate School of Bioresource and Bioenvironmental Sciences, Hakozaki 6 10 1, Fukuoka 812 8581, Japan
    Comp Biochem Physiol B Biochem Mol Biol 139:35-43. 2004
    ..To elucidate its molecular basis of the expression and physiological significance, a cDNA encoding for the Bombyx mori Tctp (BmTctp) was deduced by editing the partial cDNA sequences registered in a Bombyx EST database...
  43. ncbi Molecular cloning and expression of two novel beta-N-acetylglucosaminidases from silkworm Bombyx mori
    Takahiro Okada
    The International Center for Biotechnology, Osaka University, Suita, Osaka, Japan
    Biosci Biotechnol Biochem 71:1626-35. 2007
    ..A search using the Bombyx mori cDNA database revealed the existence of two putative beta-N-acetylglucosaminidase genes...
  44. ncbi Identification and functional analysis of Relish homologs in the silkworm, Bombyx mori
    Hiromitsu Tanaka
    Innate Immunity Research Unit, National Institute of Agrobiological Sciences, Owashi 1 2, Tsukuba, Ibaraki 305 8634, Japan
    Biochim Biophys Acta 1769:559-68. 2007
    Two cDNAs designated BmRelish1 and 2, that encode Relish homologs, were cloned from the silkworm, Bombyx mori. BmRelish1 had an IkappaB-like domain with 5 ankyrin repeats in addition to Rel homology domain (RHD), nuclear localization ..
  45. doi Expression analysis and characteristics of profilin gene from silkworm, Bombyx mori
    Zuoming Nie
    Institute of Biochemistry, College of Life Sciences, Zhejiang Sci Tech University, Hangzhou, China
    Appl Biochem Biotechnol 158:59-71. 2009
    A recombinant Bombyx mori profilin protein (rBmPFN) was overexpressed in Escherichia coli BL21. Purified rBmPFN was used to generate anti-BmPFN polyclonal antibody, which were used to determine the subcellular localization of BmPFN...
  46. doi Novel female-specific splice form of dsx in the silkworm, Bombyx mori
    Jayendra Nath Shukla
    Centre of Excellence for Genetics and Genomics of Silkmoths, Laboratory of Molecular Genetics, Centre for DNA Fingerprinting and Diagnostics, Tuljaguda, Nampally, Hyderabad, 500001, India
    Genetica 139:23-31. 2011
    The Bombyx mori doublesex (Bmdsx), a homologue of doublesex of Drosophila, is the bottom most gene of the sex determination cascade. Bmdsx plays a very crucial role in somatic sexual development...
  47. pmc The genomic underpinnings of apoptosis in the silkworm, Bombyx mori
    Jin Ye Zhang
    The Key Sericultural Laboratory of Agricultural Ministry, Institute of Sericulture and Systems Biology, Southwest University, Chongqing 400715, China
    BMC Genomics 11:611. 2010
    ..Herein we have identified apoptosis-related genes in the silkworm Bombyx mori and compared them to those from insects, mammals, and nematodes.
  48. ncbi Identification of a prothoracicostatic peptide in the larval brain of the silkworm, Bombyx mori
    Y J Hua
    Laboratory of Bioactive Substances, National Institute of Sericultural and Entomological Sciences, Ohwashi 1 2, Tsukuba, Ibaraki 305 8634, Japan
    J Biol Chem 274:31169-73. 1999
    ..ecdysteroid biosynthesis in the PG was isolated from the extracts of 2,000 larval brains of the silkworm, Bombyx mori, using a protocol that included four reversed-phase high performance liquid chromatography procedures...
  49. ncbi Interaction of Bombyx mori nucleopolyhedrovirus BRO-A and host cell protein laminin
    W K Kang
    Laboratory of Molecular Entomology and Baculovirology, RIKEN, Wako, Japan
    Arch Virol 148:99-113. 2003
    The Bombyx mori nucleopolyhedrovirus (BmNPV) contains five baculovirus repeated ORF ( bro) genes, all of which are expressed as delayed early genes...
  50. ncbi Insect sex-pheromone signals mediated by specific combinations of olfactory receptors
    Takao Nakagawa
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277 8562, Japan
    Science 307:1638-42. 2005
    We describe two male-specific olfactory receptors (ORs) in the silk moth, Bombyx mori, that are mutually exclusively expressed in a pair of adjacent pheromone-sensitive neurons of male antennae: One is specifically tuned to bombykol, the ..
  51. ncbi Myocyte enhancer factor 2 (MEF2) is a key modulator of the expression of the prothoracicotropic hormone gene in the silkworm, Bombyx mori
    Kunihiro Shiomi
    Faculty of Textile Science and Technology, Shinshu University, Nagano, Japan
    FEBS J 272:3853-62. 2005
    ..AcNPV)-mediated transient gene transfer into the central nervous sytem (CNS) of the silkworm, Bombyx mori, we identified two cis-regulatory elements that participate in the decision and the enhancement of PTTH gene ..
  52. doi Binding of the general odorant binding protein of Bombyx mori BmorGOBP2 to the moth sex pheromone components
    Xiaoli He
    Department of Biological Chemistry, Rothamsted Research, Harpenden, UK
    J Chem Ecol 36:1293-305. 2010
    ..In the silkworm, Bombyx mori (L...
  53. ncbi Prothoracicotropic hormone of the silkworm, Bombyx mori: amino acid sequence and dimeric structure
    H Kataoka
    Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo, Japan
    Agric Biol Chem 55:73-86. 1991
    Prothoracicotropic hormone (PTTH) of the silkworm, Bombyx mori, was purified and its primary structure determined for the most part...
  54. doi Abnormal red body coloration of the silkworm, Bombyx mori, is caused by a mutation in a novel kynureninase
    Yan Meng
    Department of Agricultural and Environmental Biology, The University of Tokyo, Bunkyo ku, Japan
    Genes Cells 14:129-40. 2009
    Larvae of the body color mutant red blood (rb) of the silkworm, Bombyx mori, display reddish skin whose hemolymph becomes red in air, whereas hemolymphs of normal strains become black during melanization...
  55. ncbi Molecular cloning and heterologous expression of an alpha-adrenergic-like octopamine receptor from the silkworm Bombyx mori
    A Ohtani
    Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University, Matsue, Shimane, Japan
    Insect Mol Biol 15:763-72. 2006
    A cDNA encoding an octopamine (OA) receptor (BmOAR1) was isolated from the nerve tissue of silkworm (Bombyx mori) larvae...
  56. doi A single-base deletion in an ABC transporter gene causes white eyes, white eggs, and translucent larval skin in the silkworm w-3(oe) mutant
    Natuo Kômoto
    Division of Insect Sciences, National Institute of Agrobiological Sciences, Ibaraki 305 8634, Japan
    Insect Biochem Mol Biol 39:152-6. 2009
    The w-3(oe) silkworm mutant has white eyes and eggs due to the absence of ommochrome pigments in the eye pigment cells and serosa cells...
  57. doi Immunity or digestion: glucanase activity in a glucan-binding protein family from Lepidoptera
    Yannick Pauchet
    Department of Entomology, Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans Knoell Str 8, 07745 Jena, Germany
    J Biol Chem 284:2214-24. 2009
    ..The noncatalytic betaGRPs may be evolutionarily derived from this newly described enzyme family that continues to function catalytically in digestion and/or pathogen defense...
  58. pmc Identification and expression analysis of ras gene in silkworm, Bombyx mori
    Takehiko Ogura
    Department of Applied Life Sciences, Kyoto University, Kyoto, Japan
    PLoS ONE 4:e8030. 2009
    ..We identified three ras cDNAs from the silk worm, Bombyx mori. These sequences corresponded to three Ras of Drosophila melanogaster, but not to three mammalian Ras (H-Ras, K-..
  59. ncbi A Bombyx mori gene, BmChi-h, encodes a protein homologous to bacterial and baculovirus chitinases
    Takaaki Daimon
    Laboratory of Insect Genetics and Bioscience, Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    Insect Biochem Mol Biol 33:749-59. 2003
    We have cloned and characterized a novel chitinase gene (BmChi-h) from the silkworm, Bombyx mori. BmChi-h cDNA has an open reading frame of 1,665 nucleotides, encoding a protein of 555 amino acid residues...
  60. doi Developmentally synchronized expression of two Bombyx mori Piwi subfamily genes, SIWI and BmAGO3 in germ-line cells
    Shinpei Kawaoka
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Science, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    Biochem Biophys Res Commun 367:755-60. 2008
    ..In this study, we examined the expression profiles of two Bombyx mori Piwi subfamily genes, silkworm Piwi (SIWI) and BmAGO3, which are possible partners of Bombyx piRNA-like small ..
  61. ncbi Organization of the Hox gene cluster of the silkworm, Bombyx mori: a split of the Hox cluster in a non-Drosophila insect
    Yuji Yasukochi
    Insect Genome Laboratory, National Institute of Agrobiological Sciences, Tsukuba, 305 8634, Ibaraki, Japan
    Dev Genes Evol 214:606-14. 2004
    ..chromosome (BAC) contig was constructed by chromosome walking, starting from the Hox genes of the silkworm, Bombyx mori. Bombyx orthologues of the labial (lab) and zerknult (zen) genes were newly identified...
  62. pmc Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition
    Kiyohiro Takahasi
    Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, N 21, W 11, Kita ku, Sapporo 001 0021, Japan
    Proc Natl Acad Sci U S A 106:11679-84. 2009
    ..This report shows the solution structure of the N-terminal beta-1,3-glucan recognition domain of silkworm betaGRP...
  63. ncbi Molecular cloning of the Bombyx mori prothoracicotropic hormone
    A Kawakami
    Department of Biology, School of Science, Nagoya University, Japan
    Science 247:1333-5. 1990
    ..The complementary DNAs encoding PTTH of the silkmoth Bombyx mori were cloned and characterized, and the complete amino acid sequence was deduced...
  64. ncbi Isolation and expression of the ecdysteroid-inducible angiotensin-converting enzyme-related gene in wing discs of Bombyx mori
    G X Quan
    Faculty of Agriculture, Utsunomiya University, 350 Mine, Utsunomiya, 321 8505, Tochigi, Japan
    Insect Biochem Mol Biol 31:97-103. 2001
    ..encoding a putative angiotensin-converting enzyme-related gene from the wing disc cDNA library of the silkworm, Bombyx mori (refer to as BmAcer)...
  65. pmc Identification and functional characterization of a sex pheromone receptor in the silkmoth Bombyx mori
    Takeshi Sakurai
    Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa, Kyoto 606 8502, Japan
    Proc Natl Acad Sci U S A 101:16653-8. 2004
    ..Bombykol in the silkmoth Bombyx mori was the first sex pheromone to be identified...
  66. ncbi The roles of ERK and P38 MAPK signaling cascades on embryonic diapause initiation and termination of the silkworm, Bombyx mori
    Yoshihiro Fujiwara
    Faculty of Textile Science and Technology, Department of Applied Biology, Shinshu University, Ueda, Nagano 386 8567, Japan
    Insect Biochem Mol Biol 36:47-53. 2006
    ..Phospho-ERK levels were maintained with diapause-interrupting treatment and declined with diapause-sustaining treatment. ERK phosphorylation is considered to have a role in diapause termination and in the resumption of development...
  67. doi Bombyx mori transferrin: genomic structure, expression and antimicrobial activity of recombinant protein
    Eun Young Yun
    Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Suwon 441 100, South Korea
    Dev Comp Immunol 33:1064-9. 2009
    ..In this study, we identified and characterized Bombyx mori transferrin (BmTf)...
  68. pmc Bombyx mori homologs of STIM1 and Orai1 are essential components of the signal transduction cascade that regulates sex pheromone production
    J Joe Hull
    Molecular Entomology Laboratory, RIKEN Advanced Science Institute, 2 1 Hirosawa, Wako, Saitama 351 0198, Japan
    J Biol Chem 284:31200-13. 2009
    Sex pheromone production in the pheromone gland (PG) of the silkmoth, Bombyx mori, is mediated by store-operated channels (SOCs) acting downstream of pheromone biosynthesis activating neuropeptide (PBAN) binding...
  69. doi Functional analysis of Ultrabithorax in the silkworm, Bombyx mori, using RNAi
    Mika Masumoto
    Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya, 464 8601, Japan
    Dev Genes Evol 219:437-44. 2009
    ..We examined the function of Ubx in the silkworm Bombyx mori (Bm-Ubx) by embryonic RNA interference (RNAi)...
  70. ncbi Isolation and characterization of the lysozyme-encoding gene from the silkworm Bombyx mori
    W J Lee
    Unité d Ecologie des Systèmes Vectoriels, Institut Pasteur, Paris, France
    Gene 161:199-203. 1995
    We have isolated and characterized a Bombyx mori (Bm) cDNA encoding a lysozyme (Lyz)...
  71. ncbi The mechanism of sex-specific splicing at the doublesex gene is different between Drosophila melanogaster and Bombyx mori
    M G Suzuki
    Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, 113 8657, Tokyo, Japan
    Insect Biochem Mol Biol 31:1201-11. 2001
    ..found to be sex-specifically expressed in various tissues at larval, pupal, and adult stages in the silkworm, Bombyx mori, and was alternatively spliced to yield male- and female-specific mRNAs...
  72. pmc Precursor polyprotein for multiple neuropeptides secreted from the suboesophageal ganglion of the silkworm Bombyx mori: characterization of the cDNA encoding the diapause hormone precursor and identification of additional peptides
    Y Sato
    Radioisotope Research Center, Nagoya University, Japan
    Proc Natl Acad Sci U S A 90:3251-5. 1993
    ..In the silkworm Bombyx mori, SG is known to secrete two neuropeptides, diapause hormone (DH) responsible for induction of embryonic ..
  73. ncbi Patchwork-structure serpins from silkworm (Bombyx mori) larval hemolymph
    T Sasaki
    Department of Food Science and Technology, School of Agriculture, Nagoya University, Aichi, Japan
    Eur J Biochem 202:255-61. 1991
    A new serpin (serine proteinase inhibitor), having antichymotryptic activity, was isolated from silkworm, Bombyx mori, larval hemolymph and was named silkworm antichymotrypsin II (sw-AchyII)...
  74. ncbi B96Bom encodes a Bombyx mori tyramine receptor negatively coupled to adenylate cyclase
    H Ohta
    Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University, Matsue, Shimane, Japan
    Insect Mol Biol 12:217-23. 2003
    A cDNA encoding a biogenic amine receptor (B96Bom) was isolated from silkworm (Bombyx mori) larvae, and the ligand response of the receptor stably expressed in HEK-293 cells was examined. Tyramine (TA) at 0...
  75. pmc Peptides encoded by short ORFs control development and define a new eukaryotic gene family
    Maximo Ibo Galindo
    School of Life Sciences, University of Sussex, Brighton, East Sussex, United Kingdom
    PLoS Biol 5:e106. 2007
    ..Our results open a new avenue for the annotation and functional analysis of genes and sequenced genomes, in which thousands of short ORFs are still uncharacterised...
  76. doi Glycerol kinase activity and glycerol kinase-3 gene are up-regulated by acclimation to 5 degrees C in diapause eggs of the silkworm, Bombyx mori
    Fukashi Kihara
    Sericulture and Entomoresources, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa ku, Nagoya, Aichi, Japan
    Insect Biochem Mol Biol 39:763-9. 2009
    With initiation of diapause, glycogen is converted into sorbitol and glycerol in eggs of the silkworm Bombyx mori. At diapause termination promoted by incubation at 5 degrees C, sorbitol and glycerol are utilized...
  77. doi Functional and pharmacological characterization of a beta-adrenergic-like octopamine receptor from the silkworm Bombyx mori
    Xi Chen
    Department of Life Science and Biotechnology, Faculty of Life and Environmental Science, Shimane University, Matsue, Shimane 690 8504, Japan
    Insect Biochem Mol Biol 40:476-86. 2010
    A cDNA encoding a seven-transmembrane receptor was cloned from the nervous tissues of silkworm (Bombyx mori) larvae...
  78. doi TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori
    Shi Hong Gu
    Department of Zoology, National Museum of Natural Science, 1 Kuan Chien Road, Taichung, Taiwan 404, ROC
    Insect Biochem Mol Biol 42:296-303. 2012
    ..that phosphoinositide 3-kinase (PI3K)/Akt signaling was involved in PTTH-stimulated ecdysteroidogenesis by Bombyx mori prothoracic glands. In the present study, downstream signaling of PI3K/Akt was further investigated...
  79. doi Ecdysone-responsive transcription factors determine the expression region of target cuticular protein genes in the epidermis of Bombyx mori
    Md Saheb Ali
    Faculty of Agriculture, Utsunomiya University, 350 Mine, Utsunomiya, Tochigi, 321 8505, Japan
    Dev Genes Evol 222:89-97. 2012
    ....
  80. doi Molecular characterization of a peritrophic membrane protein from the silkworm, Bombyx mori
    Xiaolong Hu
    College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China
    Mol Biol Rep 40:1087-95. 2013
    ..In the current study, a novel PM protein, designated as BmMtch, was identified from the silkworm, Bombyx mori. The open reading frame of BmMtch is 888 bp in length, encoding 295 amino acid residues consisting of two ..
  81. ncbi Purification of a beta-1,3-glucan recognition protein in the prophenoloxidase activating system from hemolymph of the silkworm, Bombyx mori
    M Ochiai
    Biochemical Laboratory, Hokkaido University, Sapporo, Japan
    J Biol Chem 263:12056-62. 1988
    The plasma fraction (referred to as plasma-CPB) of silkworm hemolymph, from which a protein with affinity to beta-1,3-glucan was specifically removed according to Yoshida et al. (Yoshida, H., Ochiai, M., and Ashida, M. (1986), Biochem...
  82. ncbi Molecular cloning of silkworm (Bombyx mori) antichymotrypsin. A new member of the serpin superfamily of proteins from insects
    H Narumi
    Department of Food Science and Technology, School of Agriculture, Nagoya University, Japan
    Eur J Biochem 214:181-7. 1993
    The cDNA of silkworm (Bombyx mori) antichymotrypsin (sw-Achy) was cloned from larval fat body and its nucleotide sequence was determined...
  83. ncbi Structure and organization of the Bombyx mori sericin 1 gene and of the sericins 1 deduced from the sequence of the Ser 1B cDNA
    A Garel
    Centre de Genetique Moleculaire et Cellulaire, U M R, Université C Bernard, Lyon I, Villeurbanne, France
    Insect Biochem Mol Biol 27:469-77. 1997
    The sericin 1 primary transcript of the silkworm Bombyx mori is differentially spliced via a tissue- and developmentally-regulated process...
  84. ncbi Phylogenetic mapping of intron positions: a case study of translation initiation factor eIF2gamma
    Veiko Krauss
    Department of Genetics, University of Leipzig, Leipzig, Germany
    Mol Biol Evol 22:74-84. 2005
    ..We also performed tree reconstructions using the eIF2gamma protein sequences and intron positioning as phylogenetic information. Our results support the monophyly of Viridoplantae, Ascomycota, Homobasidiomyceta, and Apicomplexa...
  85. ncbi Superoxide dismutase from the silkworm, Bombyx mori: sequence, distribution, and overexpression
    Kohji Yamamoto
    Laboratory of Insect Genetic Resources, Faculty of Agriculture, Kyushu University, Fukuoka, Japan
    Biosci Biotechnol Biochem 69:507-14. 2005
    ..This study focused on SOD from the silkworm, Bombyx mori (bmSOD). cDNA encoding bmSOD was amplified by reverse transcriptase-polymerase chain reaction...
  86. ncbi Phenotypic effects induced by knock-down of the period clock gene in Bombyx mori
    Federica Sandrelli
    Dipartimento di Biologia, Universita di Padova, Padua 35131, Italy
    Genet Res 89:73-84. 2007
    The lepidopteran Bombyx mori is an insect of considerable scientific and economic importance. Recently, the B. mori circadian clock gene period has been molecularly characterized. We have transformed a B...
  87. ncbi A basic-HLH transcription factor, HLH54F, is highly expressed in the prothoracic gland in the silkworm Bombyx mori and the fruit fly Drosophila melanogaster
    Toshiki Namiki
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan
    Biosci Biotechnol Biochem 73:762-5. 2009
    ..HLH54F was uncovered by the use of an expressed sequence tag database of the silkworm Bombyx mori. It was also highly expressed in the prothoracic gland of the fruit fly Drosophila melanogaster.
  88. doi Molecular characterization of heat shock proteins 90 (HSP83?) and 70 in tropical strains of Bombyx mori
    Aparna H Sosalegowda
    Department of Biochemistry, Karnatak University, Dharwad, Karnataka, India
    Proteomics 10:2734-45. 2010
    Following the concept of whole organism, we have extracted total protein from the Bombyx mori for the identification and analysis of HSPs...
  89. pmc BmDJ-1 is a key regulator of oxidative modification in the development of the silkworm, Bombyx mori
    Hiroko Tabunoki
    Department of Bioinformatics and Molecular Neuropathology, Meiji Pharmaceutical University, Tokyo, Japan
    PLoS ONE 6:e17683. 2011
    We cloned cDNA for the Bombyx mori DJ-1 protein (BmDJ-1) from the brains of larvae. BmDJ-1 is composed of 190 amino acids and encoded by 672 nucleotides...
  90. pmc CD36 homolog divergence is responsible for the selectivity of carotenoid species migration to the silk gland of the silkworm Bombyx mori
    Takashi Sakudoh
    Division of Radiological Protection and Biology, National Institute of Infectious Diseases, Shinjuku Tokyo 162 8640, Japan
    J Lipid Res 54:482-95. 2013
    ..The products of the Yellow cocoon (C) gene and the Flesh (F) gene of the silkworm Bombyx mori determine the selectivity for transport of lutein and β-carotene, respectively, to the silk gland...
  91. doi Reaper homologue IBM1 in silkworm Bombyx mori induces apoptosis upon baculovirus infection
    Yu Wu
    Institute of Life Science, Jiangsu University, Zhenjiang 212013, China
    FEBS Lett 587:600-6. 2013
    ..b>Bombyx mori IBM1 gene, a Drosophila Reaper orthologue, is localised in mitochondria and can induce a mitochondrial membrane ..
  92. pmc BmPAH catalyzes the initial melanin biosynthetic step in Bombyx mori
    Ping Chen
    State Key Laboratory of Silkworm Genome Biology and College of Biotechnology, Southwest University, Chongqing, China College of Biotechnology, Southwest University, Chongqing, China
    PLoS ONE 8:e71984. 2013
    Pigmentation during insect development is a primal adaptive requirement. In the silkworm, melanin is the primary component of larval pigments...
  93. ncbi Structures and organization of major plasma protein genes of the silkworm Bombyx mori
    S Mori
    Department of Biology, Tokyo Metropolitan University, Japan
    J Mol Biol 218:7-12. 1991
    In the silkworm, Bombyx mori, a group of structurally related proteins, termed 30K proteins, accumulate in the hemolymph of the last instar larvae...
  94. ncbi Isolation of actin genes in Bombyx mori: the coding sequence of a cytoplasmic actin gene expressed in the silk gland is interrupted by a single intron in an unusual position
    N Mounier
    Biochimie 68:1053-61. 1986
    ..gene(s) coding for the actin present in the microfilaments involved in the secretion of silk, we have probed a Bombyx mori genomic library with a Drosophila actin cDNA clone and selected 16 recombinant phages...
  95. ncbi Heat-inducible transgenic expression in the silkmoth Bombyx mori
    Mirka Uhlirova
    University of South Bohemia, Branisovká 31, České Budějovice 370 05, Czech Republic
    Dev Genes Evol 212:145-51. 2002
    ..the piggyBac 3xP3-EGFP vector to test whether the Drosophila heat shock hsp70 promoter will be active in the live silkworm. We modified the original vector by cloning the coding sequence for Bombyx nuclear receptor Ftz-F1 between the ..
  96. ncbi Aminopeptidase N isoforms from the midgut of Bombyx mori and Plutella xylostella -- their classification and the factors that determine their binding specificity to Bacillus thuringiensis Cry1A toxin
    Kazuko Nakanishi
    Graduate School of Bio Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan
    FEBS Lett 519:215-20. 2002
    Novel aminopeptidase N (APN) isoform cDNAs, BmAPN3 and PxAPN3, from the midguts of Bombyx mori and Plutella xylostella, respectively, were cloned, and a total of eight APN isoforms cloned from B. mori and P...
  97. ncbi Genomic sequence of a 320-kb segment of the Z chromosome of Bombyx mori containing a kettin ortholog
    Y Koike
    Department of Agricultural and Environmental Biology, University of Tokyo, Yayoi 1 1 1, Bunkyo ku, 113 8657 Tokyo, Japan
    Mol Genet Genomics 269:137-49. 2003
    The sex chromosome constitution of the silkworm, Bombyx mori, is ZW in the female and ZZ in the male...
  98. ncbi Isolation and comparison of different ecdysone-responsive cuticle protein genes in wing discs of Bombyx mori
    Takanori Noji
    Utsunomiya University, Faculty of Agriculture, 350 Mine, Utsunomiya, Tochigi 321 8505, Japan
    Insect Biochem Mol Biol 33:671-9. 2003
    Microarray analysis was used to isolate an ecdysone up-regulated cuticle protein gene from wing discs of Bombyx mori. Transcripts of isolated cDNAs were identified by Northern blot analysis...
  99. pmc A lipase isolated from the silkworm Bombyx mori shows antiviral activity against nucleopolyhedrovirus
    Kangayam M Ponnuvel
    Innate Immunity Laboratory, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305 8634, Japan
    J Virol 77:10725-9. 2003
    A protein showing strong antiviral activity against Bombyx mori nucleopolyhedrovirus (BmNPV) was purified from the digestive juice of B. mori larvae...
  100. ncbi ERK/MAPK regulates ecdysteroid and sorbitol metabolism for embryonic diapause termination in the silkworm, Bombyx mori
    Yoshihiro Fujiwara
    Department of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, Ueda, Nagano 386 8567, Japan
    J Insect Physiol 52:569-75. 2006
    The eggs of the silkworm Bombyx mori undergo a state of suspended overt development and diminished metabolism called "diapause" to escape adverse environmental conditions...
  101. ncbi A genomewide survey of homeobox genes and identification of novel structure of the Hox cluster in the silkworm, Bombyx mori
    Chun Li Chai
    The Key Sericultural Laboratory of Agricultural Ministry, College of Biotechnology, Institute of Sericulture and Systems Biology, Southwest University, Chongqing, China
    Insect Biochem Mol Biol 38:1111-20. 2008
    ..We have identified 102 homeobox genes in the typical insect of Lepidoptera, Bombyx mori, based on the newly assembled genome sequence with 9X coverage...

Research Grants23

  1. Convergent Molecular Evolution of Moth and Spider Silks
    NADIA AYOUB; Fiscal Year: 2009
    ..2) Expression patterns of the domesticated silkworm and black widow silk glands will be compared to determine if convergence in gene expression can, in part, explain ..
  2. A novel transgenic silkworm system for recombinant glycoprotein production
    Donald L Jarvis; Fiscal Year: 2010
    ..The long-term objective of this proposal is to genetically engineer the silkworm to fulfill these requirements and provide a new system for recombinant glycoprotein production...
  3. SILK SCAFFOLDS FOR BONE FORMATION
    David Kaplan; Fiscal Year: 2003
    ..Silk proteins will be prepared, including regenerated silkworm silk and different spider silks using recombinant DNA techniques (with and without encoded RGD and cysteines)...
  4. Circadian Clock: Differential Cryptochrome Functions
    Steven M Reppert; Fiscal Year: 2011
    ..in vivo the critical clockwork function of insect CRY2 by targeted gene inactivation in the commercial silkworm Bombyx mori using a zinc finger nuclease strategy...
  5. Peijing Jeremy Wang; Fiscal Year: 2016
    ..and 3) biochemically characterize the role of the MOV10L1 homologue in piRNA biogenesis in cultured silkworm (Bombyx mori) BmN4 ovarian cell lines...
  6. Yohei Kirino; Fiscal Year: 2016
    ..of PIWI sDMAs in the piRNA pathway, we will express PIWI proteins containing or lacking sDMAs in BmN4 (a Bombyx mori ovary-derived cultured cell line) that is an excellent cell system for piRNA research due to its endogenous ..
  7. Recombinant Subunit Protein for Flu Vaccine
    Carolyn Weeks Levy; Fiscal Year: 2006
    ..The proteins will also be expressed in the Bombyx mori system to provide Hawaii Biotech Inc an alternative expression system to the Drosophila system...
  8. CONTROL OF TRNA GENE EXPRESSION IN BOMBYX MORI
    KAREN SPRAGUE; Fiscal Year: 1993
    The aim of the proposed work is to investigate the mechanism of transcription by silkworm RNA polymerase III in vitro. Much of our effort will focus on a novel transcription component, Factor X, that our laboratory has recently isolated...
  9. MULTIGENE FAMILIES: STRUCTURE, EXPRESSION AND EVOLUTION
    Thomas Eickbush; Fiscal Year: 1991
    ..of the chorion (eggshell) by the monolayer of follicle cells surrounding the maturing oocyte of the silkmoth, Bombyx mori. In these cells the synthesis of over 100 chorion proteins follows a precise temporal pattern corresponding to ..
  10. REGULATION OF AMINOACYL-TRNA SYNTHETASES IN BOMBYX
    DAVID DIGNAM; Fiscal Year: 1990
    ..studies will be to determine how the levels of aminoacyl-tRNA synthetases are regulated in a higher eukaryote, Bombyx mori. This organism will be employed because its silkgland specializes its protein synthetic apparatus for the ..
  11. MECHANISM OF SELECTIVE EXPRESSION OF TRNA GENES
    KAREN SPRAGUE; Fiscal Year: 1999
    ..SG transcription in vitro will be functionally tested in vivo by determining their ability to regulate SG transcription when ectopically expressed in cultured Drosophila and silkworm cells and in intact, differentiated silkworm tissues.
  12. EUKARYOTIC GENE ISOLATION AND EXPRESSION
    John Morrow; Fiscal Year: 1980
    We propose to learn whether putative transposable elements, which are repeated DNA sequences of Bombyx mori, have the sequence at one end duplicated at the other end...
  13. Gustatory and olfactory receptors of Anopheles gambiae
    Hugh Robertson; Fiscal Year: 2006
    ..This work will also contribute to our overall understanding of the molecular basis of chemoreception in insects and other animals. [unreadable] [unreadable]..
  14. MARINER TRANSPOSONS OF MAMMALS
    Hugh Robertson; Fiscal Year: 2001
    ..It will also reveal how occasionally particular copies of transposons can become integral parts of their host genetic complements. ..
  15. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  16. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  17. Mosquito Immunity to Alphaviruses
    Brian Foy; Fiscal Year: 2006
    ..3) Characterize the mechanisms that Culex tritaeniorhynchus mosquitoes use to clear Sindbis virus-infected midgut cells. [unreadable] [unreadable]..
  18. TRANSGENIC ENGINEERING OF AEDINE MOSQUITOES
    Malcolm Fraser; Fiscal Year: 2005
    ..This research will provide an exciting and much needed capability for significant enhancement of the basic research effort in mosquito genetics and physiology. ..
  19. Functional Characterization of Drosophila Odor Receptors
    ELISSA HALLEM; Fiscal Year: 2005
    ..The contribution of individual odor receptors to receptor neuron response properties will be examined, thus furthering our understanding of both olfactory coding and the molecular basis of odor-receptor interactions. ..
  20. INSECT HEME OXYGENASE
    Boris Dunkov; Fiscal Year: 2004
    ..The organ specific expression will be studied in larvae and in female mosquitoes at various stages before and after blood feeding. ..
  21. Cocaine and monoamine transporters
    HOWARD GU; Fiscal Year: 2009
    ..These compounds would be excellent drug candidates for the development of pharmacological treatment for cocaine addiction. ..

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