golden hamster

Summary

Alias: Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Mesocricetus auratus, Golden hamsters, Syrian hamsters, Microcricetus aureus

Top Publications

  1. pmc Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis
    P C Melby
    Department of Veterans Affairs Medical Center, and Department of Medicine, The University of Texas Health Science Center, San Antonio 78284 7881, USA
    Infect Immun 66:2135-42. 1998
  2. ncbi The hamster as a model of human visceral leishmaniasis: progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response
    P C Melby
    Medical Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, San Antonio, TX 78284, USA
    J Immunol 166:1912-20. 2001
  3. pmc The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4
    Madhuri Chattopadhyay
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA
    J Am Chem Soc 127:12647-56. 2005
  4. pmc Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals
    Lance J Kriegsfeld
    Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 103:2410-5. 2006
  5. ncbi Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen
    Luis E Perez
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, 7400 Merton Minter Drive, San Antonio, TX 78229, USA
    J Immunol 176:5519-28. 2006
  6. pmc The prion protein is a combined zinc and copper binding protein: Zn2+ alters the distribution of Cu2+ coordination modes
    Eric D Walter
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA
    J Am Chem Soc 129:15440-1. 2007
  7. pmc Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis
    Claudia M Espitia
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, 7400 Merton Minter, San Antonio, Texas, USA
    BMC Immunol 11:31. 2010
  8. pmc Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression
    E Yaneth Osorio
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
    PLoS Pathog 8:e1002417. 2012
  9. ncbi Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
    K Basler
    Cell 46:417-28. 1986
  10. ncbi Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus
    D W Hein
    Department of Pharmacology and Toxicology, University of North Dakota School of Medicine, Grand Forks 58203
    Cancer Res 53:509-14. 1993

Research Grants

  1. Richard H Melloni; Fiscal Year: 2015
  2. TASTE QUALITY REPRESENTATION IN THE SOLITARY NUCLEUS
    MARION FRANK; Fiscal Year: 1992
  3. TEMPORAL INTEGRATION OF PHOTOPERIODIC SIGNALS IN MAMMALS
    Michael Gorman; Fiscal Year: 2002
  4. Neurobiology of Social Behavior
    ELLIOTT ALBERS; Fiscal Year: 2005
  5. TEMPORAL INTEGRATION OF PHOTOPERIODIC SIGNALS IN MAMMALS
    Michael R Gorman; Fiscal Year: 2010
  6. H Craig Heller; Fiscal Year: 2016
  7. Circadian Biology at the Supra-Organismal Level
    William J Schwartz; Fiscal Year: 2013
  8. Integrative Neurobiology of Social Processes
    S Marc Breedlove; Fiscal Year: 2013
  9. FAT CELL PROLIFERATION IN OBESITY--MODULATING FACTORS
    Roy Martin; Fiscal Year: 1999
  10. ENVIRONMENTAL CONTROL OF SEASONAL WEIGHT CYCLES
    George Wade; Fiscal Year: 1992

Patents

  1. MODULATION OF APOLIPOPROTEIN C-III EXPRESSION
  2. CELL DIFFERENTIATION MARKER AND ITS USES
  3. Electrical conductors and devices from prion-like proteins
  4. Prion proteins and their uses
  5. Modulators of the constitutive androstane receptor (car): screening and treatment of hypercholesterolemia
  6. Recombinant prion-like genes and proteins and materials and methods comprising same
  7. Differential Expression Profiling Analysis of Cell Culture Phenotypes and the Uses Thereof
  8. Inhibitor and enhancer of DNA uptake via endocytosis, virus infection inhibitor, virus infection prophylactic agent and virus infection enhancer, and gene marker, monoclonal antibody, hybridoma and use thereof
  9. Vaccine and Immunity method
  10. Constitutively Desensitized G Protein-Coupled Receptors

Detail Information

Publications412 found, 100 shown here

  1. pmc Cloning of Syrian hamster (Mesocricetus auratus) cytokine cDNAs and analysis of cytokine mRNA expression in experimental visceral leishmaniasis
    P C Melby
    Department of Veterans Affairs Medical Center, and Department of Medicine, The University of Texas Health Science Center, San Antonio 78284 7881, USA
    Infect Immun 66:2135-42. 1998
    The Syrian golden hamster (Mesocricetus auratus) is uniquely susceptible to a variety of intracellular pathogens and is an excellent model for a number of human infectious diseases...
  2. ncbi The hamster as a model of human visceral leishmaniasis: progressive disease and impaired generation of nitric oxide in the face of a prominent Th1-like cytokine response
    P C Melby
    Medical Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, San Antonio, TX 78284, USA
    J Immunol 166:1912-20. 2001
    ..Remarkably, infection of the Syrian hamster (Mesocricetus auratus) with L...
  3. pmc The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4
    Madhuri Chattopadhyay
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA
    J Am Chem Soc 127:12647-56. 2005
    ..This work provides the first complete characterization of all dominant copper coordination modes at pH 7.4...
  4. pmc Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals
    Lance J Kriegsfeld
    Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 103:2410-5. 2006
    ....
  5. ncbi Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen
    Luis E Perez
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, 7400 Merton Minter Drive, San Antonio, TX 78229, USA
    J Immunol 176:5519-28. 2006
    ....
  6. pmc The prion protein is a combined zinc and copper binding protein: Zn2+ alters the distribution of Cu2+ coordination modes
    Eric D Walter
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, USA
    J Am Chem Soc 129:15440-1. 2007
  7. pmc Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis
    Claudia M Espitia
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, 7400 Merton Minter, San Antonio, Texas, USA
    BMC Immunol 11:31. 2010
    The Syrian hamster, Mesocricetus auratus, has distinct immunological features and is uniquely susceptible to intracellular pathogens. Studies in hamsters are limited by the relative unavailability of tools to conduct immunological studies...
  8. pmc Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression
    E Yaneth Osorio
    Research Service, Department of Veterans Affairs Medical Center, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
    PLoS Pathog 8:e1002417. 2012
    ..donovani infection induces macrophage STAT6 activation and STAT6-dependent arg1 expression, which do not require but are amplified by type 2 cytokines, and which contribute to impaired control of infection...
  9. ncbi Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
    K Basler
    Cell 46:417-28. 1986
    ....
  10. ncbi Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus
    D W Hein
    Department of Pharmacology and Toxicology, University of North Dakota School of Medicine, Grand Forks 58203
    Cancer Res 53:509-14. 1993
    ..is regulated at the polymorphic acetyltransferase (NAT2) gene locus in humans and other mammals such as Syrian hamsters. Human slow acetylator phenotypes have been associated with increased incidences of urinary bladder cancers, ..
  11. ncbi Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure
    E E McConnell
    ToxPath, Inc, 3028 Ethan Lane, Raleigh, NC 27613, USA
    Inhal Toxicol 11:785-835. 1999
    ..Groups of 140 weanling male Syrian golden hamsters were exposed via nose-only inhalation for 6 h/day, 5 days/wk for 78 wk to either filtered air (chamber ..
  12. ncbi An essential role for ovarian inhibin in pineal gland-mediated anestrus in Syrian hamsters
    B Benson
    Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson 85724 5044, USA
    J Pineal Res 25:5-11. 1998
    When transferred from long photoperiod (LP) to short photoperiod (SP), female Syrian hamsters exhibit depressions of follicle stimulating hormone (FSH) and follicular development, cessation of ovulation, and marked ovarian interstitial ..
  13. ncbi Conjugated linoleic acid isomers reduce blood cholesterol levels but not aortic cholesterol accumulation in hypercholesterolemic hamsters
    Thomas A Wilson
    Department of Clinical Laboratory and Nutritional Sciences, Center for Health and Disease Research, University of Massachusetts Lowell, Lowell, Massachusetts 01854 5125, USA
    Lipids 41:41-8. 2006
    ..One hundred male F1B strain Syrian Golden Hamsters (Mesocricetus auratus) (BioBreeders Inc...
  14. ncbi Apoptosis and molecular pathways in the seminiferous epithelium of aged and photoinhibited Syrian hamsters (Mesocricetus auratus)
    Eva Morales
    Department of Cell Biology, Faculty of Medicine, Campus de Espinardo, University of Murcia, E 30071 Murcia, Spain
    J Androl 28:123-35. 2007
    Aging and short photoperiod exposure induce germ cell apoptosis in the Syrian hamster; however, the specific germ cells affected and the molecular pathways triggered have not been elucidated...
  15. ncbi Subcellular distributions of calcitonin gene-related peptide (CGRP)-like immunoreactivity in the subcommissural organ of the golden hamster (Mesocricetus auratus)
    Mang Hung Tsai
    Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, 1, Sec 1, Jen Ai Road, 100 Taipei, Taiwan
    Neurosci Res 47:85-95. 2003
    ..The abundant amount of CGRP in ependymocytes of SCO and RF in the third ventricle suggests a significant endocrine function of CGRP in hamster SCO...
  16. ncbi Rice bran oil and oryzanol reduce plasma lipid and lipoprotein cholesterol concentrations and aortic cholesterol ester accumulation to a greater extent than ferulic acid in hypercholesterolemic hamsters
    Thomas A Wilson
    Department of Clinical Laboratory and Nutritional Sciences, Center for Health and Disease Research, University of Massachusetts Lowell, Lowell, MA 01854, USA
    J Nutr Biochem 18:105-12. 2007
    ..Forty-eight F(1)B Golden Syrian hamsters (Mesocricetus auratus) (BioBreeders, Watertown, MA) were group housed (three per cage) in cages with bedding in an air-..
  17. ncbi Quantitative differences in the circadian rhythm of locomotor activity and vasopressin and vasoactive intestinal peptide gene expression in the suprachiasmatic nucleus of tau mutant compared to wildtype hamsters
    K Scarbrough
    Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA
    Brain Res 736:251-9. 1996
    ..of homozygous tau mutant hamsters bred in our colony exhibit several differences when compared to wildtype golden hamsters. In addition, tau mutant hamsters respond to saturating white light pulses presented between circadian time (..
  18. pmc Chronic inhalation study of fiber glass and amosite asbestos in hamsters: twelve-month preliminary results
    T W Hesterberg
    Schuller International, Inc, Littleton, Colorado, USA
    Environ Health Perspect 105:1223-9. 1997
    ..The study includes 18 months of inhalation exposure followed by lifetime recovery. Syrian golden hamsters are exposed, nose only, for 6 hr/day, 5 day/week to size-selected test fibers: MMVF10a (Schuller 901 ..
  19. doi Schistosoma japonicum-infected hamsters (Mesocricetus auratus) used as a model in experimental chemotherapy with praziquantel, artemether, and OZ compounds
    Shu Hua Xiao
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, MOH, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai, 200025, PR China
    Parasitol Res 108:431-7. 2011
    ..praziquantel, and ozonide (OZ) compounds (synthetic trioxolanes, secondary ozonides) in hamster (Mesocricetus auratus) model...
  20. ncbi Influence of photoinhibition on the morphology and function of pituitary lactotropes in male golden hamsters
    Gloria M Console
    Cátedra de Histología Embriología B, Facultad de Ciencias Medicas, UNLP, Comisión de Investigaciones Científicas Buenos Aires CICBA, Argentina
    Neuroendocrinology 75:316-25. 2002
    ..was to analyze the possible quantitative immunohistochemical and ultrastructural changes of PRL cells in male golden hamsters undergoing regression and spontaneous recrudescence, correlating the morphological findings with circulating ..
  21. doi The benzodiazepine diazepam demonstrates the usefulness of Syrian hamsters as a model for anxiety testing: evaluation of other classes of anxiolytics in comparison to diazepam
    Robert L Gannon
    Department of Biology, Valdosta State University, Valdosta, GA 31698, USA
    Behav Brain Res 218:8-14. 2011
    ..In animal models, Syrian hamsters have been used extensively to study the pharmacology of circadian rhythms, while rats and mice are used to ..
  22. ncbi Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig
    B G Lake
    TNO BIBRA International Ltd, Woodmansterne Road, Carshalton, Surrey, UK
    Mutat Res 448:213-25. 2000
    ..Male Sprague-Dawley rats, Syrian hamsters and Dunkin-Hartley guinea pigs were given daily oral doses of 0 (corn oil) and 75 mg/kg MCP for periods of 6 ..
  23. ncbi Role of the central amygdala in social communication in Syrian hamsters (Mesocricetus auratus)
    M Bamshad
    Departments of Biology and Psychology, Georgia State University, Atlanta 30303, USA
    Brain Res 744:15-22. 1997
    In Syrian hamsters, vasopressin (AVP) controls a form of scent marking called flank marking. Microinjection and lesion studies have identified several components of the neural circuit controlling this behavior...
  24. pmc Corticotropin-releasing factor receptors in the dorsal raphe nucleus modulate social behavior in Syrian hamsters
    Matthew A Cooper
    Department of Psychology, Austin Peay Building, University of Tennessee, Knoxville, TN 37996 0900, USA
    Psychopharmacology (Berl) 194:297-307. 2007
    In Syrian hamsters (Mesocricetus auratus), social defeat produces a prolonged change in subsequent agonistic behavior termed conditioned defeat...
  25. ncbi Effects of Diaspirin Crosslinked Hemoglobin (DCLHb) on microcirculation and local tissue pO2 of striated skin muscle following resuscitation from hemorrhagic shock
    Sven Hungerer
    Department for Surgery, Trauma Clinic Murnau, Murnau, Germany
    Artif Cells Blood Substit Immobil Biotechnol 34:455-71. 2006
    ..leukocyte-endothelial cell interaction and local tissue oxygenation in striated skin muscle of Syrian golden hamsters during and after resuscitation from hemorrhagic shock...
  26. doi The effect of tribendimidine and its metabolites against Necator americanus in golden hamsters and Nippostrongylus braziliensis in rats
    Jian Xue
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology, Shanghai, People s Republic of China
    Parasitol Res 106:775-81. 2010
    ..americanus-infected hamsters; the effect of oral dADT against N. braziliensis in rats is somewhat better than TBD, while AdADT endorses poor effect; and TPAL and TPAC are ineffective metabolites of TBD against both species of nematodes...
  27. pmc The S segment of Punta Toro virus (Bunyaviridae, Phlebovirus) is a major determinant of lethality in the Syrian hamster and codes for a type I interferon antagonist
    Lucy A Perrone
    Department of Pathology, Centers for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77550 0609, USA
    J Virol 81:884-92. 2007
    ..of Punta Toro virus (PTV), isolated from febrile humans in Panama, cause a differential pathogenesis in Syrian hamsters, which could be a useful model for understanding the virulence characteristics and differential outcomes in ..
  28. ncbi Effects of emphysema on diaphragm blood flow during exercise
    W L Sexton
    Department of Physiology, Kirksville College of Osteopathic Medicine, Kirksville, Missouri 63501, USA
    J Appl Physiol (1985) 84:971-9. 1998
    ..Male Syrian Golden hamsters were randomly divided into emphysema (E; intratracheal elastase 25 units/100 g body wt) and control (C; ..
  29. ncbi Testicular function after local injection of 6-hydroxydopamine or norepinephrine in the golden hamster (Mesocricetus auratus)
    A Mayerhofer
    Department of Physiology, School of Medicine, Southern Illinois University, Carbondale 62901 6512
    J Androl 11:301-11. 1990
    ..This in vivo and in vitro study in the adult golden hamster examines testicular function after unilateral intratesticular application of a single dose of 6-..
  30. ncbi Chemopreventative effect of a cyclooxygenase-2-specific inhibitor (etodolac) on chemically induced biliary carcinogenesis in hamsters
    Noritsugu Tsuneoka
    Department of Transplantation and Digestive Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Carcinogenesis 26:465-9. 2005
    ..b>Syrian golden hamsters were subjected to choledochojejunostomy and then received subcutaneous injections of N-nitrosobis(2-..
  31. ncbi Pressor effects elicited by stimulation within the medullary raphe nuclei of the golden hamster (Mesocricetus auratus)
    M G Faria
    Departamento de Ciencias Fisiologicas, Universidade Federal do Espirito Santo, Brasil
    Braz J Med Biol Res 29:533-40. 1996
    ..2 g/kg, iv, after ether induction) golden hamsters (Mesocricetus auratus, 130 to 150 g, either sex)...
  32. ncbi Volitional ethanol consumption affects overall serotonin metabolism in Syrian golden hamsters (Mesocricetus auratus)
    W M Keung
    Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115, USA
    Biochem Biophys Res Commun 271:823-30. 2000
    ..metabolites 5-hydroxyindole-3-acetic acid (5-HIAA) and 5-hydroxytryptophol (5-HTOL) in the urine of Syrian golden hamsters (Mesocricetus auratus) and used to study the effect of volitional ethanol consumption on overall 5-HT ..
  33. ncbi Effect of host age in the distribution of adult Trichinella zimbabwensis in the small intestines of golden hamsters (Mesocricetus auratus) and Balb C mice
    S Mukaratirwa
    Faculty of Veterinary Science, Department of Paraclinical Veterinary Studies, P O Box MP 167, Mount Pleasant, Harare, Zimbabwe
    Onderstepoort J Vet Res 70:169-73. 2003
    Golden hamsters (Mesocricetus auratus) and Balb C mice were experimentally infected with Trichinella zimbabwensis to determine the effect of host age in the distribution of adult stages in the small intestines...
  34. doi The bed nucleus of the stria terminalis in the Syrian hamster (Mesocricetus auratus): absence of vasopressin expression in standard and wild-derived hamsters and galanin regulation by seasonal changes in circulating sex steroids
    M Bolborea
    Tierarztliche Hochschule, Institut fur Zoologie, Bunteweg 17, 30559 Hannover, Germany
    Neuroscience 165:819-30. 2010
    ..was completely absent in both breeding stocks, confirming the absence of BNST vasopressin expression in Mesocricetus auratus and ruling out a breeding artefact...
  35. doi Enhancement of shortening velocity, power, and acto-myosin crossbridge (CB) kinetics following long-term treatment with propionyl-L-carnitine, coenzyme Q10, and omega-3 fatty acids in BIO TO-2 cardiomyopathic Syrian hamsters papillary muscle
    Romina Vargiu
    Department of Science Applied to Biosystems, Section of Physiology and Human Nutrition, University of Cagliari, Italy
    Biofactors 36:229-39. 2010
    ..The BIO TO-2 cardiomyopathic Syrian Hamsters (CMSHs) represent an animal model of idiopathic DCM...
  36. ncbi Microvascular response to compartment syndrome-like external pressure elevation: an in vivo fluorescence microscopic study in the hamster striated muscle
    B Vollmar
    Institute for Clinical and Experimental Surgery, University of Saarland, Homburg, Germany
    J Trauma 46:91-6. 1999
    ..To quantitatively assess the nature and the magnitude of the microvascular response of striated muscle tissue upon elevation of external pressure, as in compartment syndrome...
  37. ncbi Energetics of offspring production: a comparison of a marsupial (Monodelphis domestica) and a eutherian (Mesocricetus auratus)
    M J Hsu
    Department of Evolution, Ecology, and Organismal Biology, Ohio State University, Columbus 43210, USA
    J Comp Physiol B 169:67-76. 1999
    ..the energetic cost of reproduction during gestation and lactation of a eutherian, the golden hamster (Mesocricetus auratus), and a similar-sized (60,120 g) marsupial, the gray short-tailed opossum (Monodelphis domestica)...
  38. ncbi Imbalance of estrogen homeostasis in kidney and liver of hamsters treated with estradiol: implications for estrogen-induced initiation of renal tumors
    E L Cavalieri
    The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198 6805, USA
    Chem Res Toxicol 14:1041-50. 2001
    ..Treatment of male Syrian golden hamsters with estrogens or 4-catechol estrogens (4-CE), but not 2-CE, induces kidney, but not liver, tumors...
  39. ncbi Collagen matrix in development and progression of experimentally induced respiratory neoplasms in the hamster
    J Laitakari
    Department of Pathology, University of Oulu, Finland
    Toxicol Pathol 29:514-27. 2001
    Intratracheal instillations of 7H-dibenzo(c, g)carbazole (DBC), a tobacco smoke component, into Syrian golden hamsters, resulted in preneoplastic lesions and benign and malignant respiratory neoplasms...
  40. doi Dietary n-3 polyunsaturated fatty acids and endothelium dysfunction induced by lysophosphatidylcholine in Syrian hamster aorta
    Anthony Lucas
    INRA UMR 1154, Chatenay Malabry F 92296, France
    Metabolism 57:233-40. 2008
    ..Golden Syrian hamsters were fed for 6 weeks with a control diet or an EPA- or DHA-supplemented diet...
  41. doi Arginine-vasopressin and the regulation of aggression in female Syrian hamsters (Mesocricetus auratus)
    Stephanie J Gutzler
    Neuroscience Institute, Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA 30302 3966, USA
    Eur J Neurosci 31:1655-63. 2010
    ..studies have demonstrated that AVP regulates behaviors such as social communication and aggression in Syrian hamsters through the V1a receptor subtype...
  42. pmc The role of the medial preoptic area in appetitive and consummatory reproductive behaviors depends on sexual experience and odor volatility in male Syrian hamsters
    L E Been
    Georgia State University, Neuroscience Institute, 100 Piedmont Avenue, Atlanta, GA 30303, USA
    Neuroscience 170:1120-32. 2010
    In Syrian hamsters (Mesocricetus auratus), the expression of reproductive behavior requires the perception and discrimination of sexual odors...
  43. doi Adolescent anabolic androgenic steroids reorganize the glutamatergic neural circuitry in the hypothalamus
    Maria Carrillo
    Behavioral Neuroscience Program, Department of Psychology, 125 Nightingale Hall, Northeastern University, 360 Huntington Avenue, Boston, MA 02155, USA
    Brain Res 1249:118-27. 2009
    ..AAS) during adolescence alters the activity of various neurotransmitter systems in male Syrian hamsters (Mesocricetus auratus)...
  44. pmc Lesions that functionally disconnect the anterior and posterodorsal sub-regions of the medial amygdala eliminate opposite-sex odor preference in male Syrian hamsters (Mesocricetus auratus)
    P M Maras
    Department of Psychology, Center for Behavioral Neuroscience, Neuroscience Institute, Georgia State University, Atlanta, GA 30302 5030, USA
    Neuroscience 165:1052-62. 2010
    In many rodent species, such as Syrian hamsters, reproductive behavior requires neural integration of chemosensory information and steroid hormone cues...
  45. pmc Lesions of the posterior bed nucleus of the stria terminalis eliminate opposite-sex odor preference and delay copulation in male Syrian hamsters: role of odor volatility and sexual experience
    Laura E Been
    Neuroscience Institute, Georgia State University, Atlanta, GA 30302 5030, USA
    Eur J Neurosci 32:483-93. 2010
    In Syrian hamsters (Mesocricetus auratus), the expression of reproductive behavior requires the perception of social odors...
  46. pmc Blocking oxytocin receptors inhibits vaginal marking to male odors in female Syrian hamsters
    Luis A Martinez
    Neuroscience Institute, Center for Behavioral Neuroscience, Georgia State University, PO Box 5030, Atlanta, GA 30302 5030, USA
    Physiol Behav 101:685-92. 2010
    In Syrian hamsters (Mesocricetus auratus), precopulatory behaviors such as vaginal scent marking are essential for attracting a suitable mate...
  47. ncbi The photoreceptive capacity of the developing pineal gland and eye of the golden hamster (Mesocricetus auratus)
    R G Foster
    Department of Integrative and Molecular Neuroscience, Division of Neuroscience and Psychological Medicine, Imperial College London, Faculty of Medicine, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK
    J Neuroendocrinol 15:355-63. 2003
    ..Using the golden hamster (Mesocricetus auratus) as our model, we applied biochemical approaches to look for a functional photopigment within the pineal ..
  48. ncbi Seasonal and daily changes in the capacity for nonshivering thermogenesis in the golden hamsters housed under semi-natural conditions
    Małgorzata Jefimow
    Department of Animal Physiology, Institute of General and Molecular Biology, N Copernicus University, Gagarina 9 St, Toruń PL 87 100, Poland
    Comp Biochem Physiol A Mol Integr Physiol 137:297-309. 2004
    ..preferred ambient temperature (PT(a)) and activity after noradrenaline (NA) injections in golden hamsters (Mesocricetus auratus) housed under semi-natural conditions were investigated...
  49. ncbi The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus
    Shuhua Xiao
    Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
    Exp Parasitol 118:32-40. 2008
    ..previously reported the successful adaptation of human hookworm Necator americanus in the golden hamster, Mesocricetus auratus. This animal model was used to test a battery of hookworm (N...
  50. doi Canine visceral leishmaniasis: asymptomatic infected dogs as a source of L. infantum infection
    Abdolali Moshfe
    Department of Medical Parasitology and Mycology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
    Acta Trop 112:101-5. 2009
    ..was extracted from skin and peripheral blood tissues of each dog and tested by PCR. Sixty-six Syrian golden hamsters (Mesocricetus auratus) were used for the determination of infectivity and pathogenicity of L...
  51. pmc Neural mechanisms of individual and sexual recognition in Syrian hamsters (Mesocricetus auratus)
    Aras Petrulis
    Neuroscience Institute, Georgia State University, Atlanta, GA 30302 5030, USA
    Behav Brain Res 200:260-7. 2009
    ..Due to its heavy reliance on odor cues, we have used the Syrian hamster as our model species for investigating the neural regulation of social recognition...
  52. ncbi Leishmania donovani-derived lipophosphoglycan plus BCG induces a Th1 type immune response but does not protect Syrian golden hamsters (Mesocricetus auratus) and BALB/c mice against Leishmania donovani
    W K Tonui
    Centre for Biotechnology Research and Development, Kenya Medical Research Institute, PO Box 54840, Nairobi, Kenya
    Onderstepoort J Vet Res 70:255-63. 2003
    ..BCG) as a vaccine candidate against visceral leishmaniosis in susceptible BALB/c mouse and Syrian golden hamster (Mesocricetus auratus) models was investigated...
  53. ncbi Chronic St. Louis encephalitis virus infection in the golden hamster (Mesocricetus auratus)
    Marina T Siirin
    Department of Pathology and Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Am J Trop Med Hyg 76:299-306. 2007
    To further study the phenomenon of flavivirus persistent infection, golden hamsters (Mesocricetus auratus) were inoculated intraperitoneally with a low pathogenicity strain of St. Louis encephalitis virus (SLEV)...
  54. ncbi Induction of P-450 isoenzyme activities in Syrian golden hamster liver compared to rat liver as probed by the rate of 7-alkoxyresorufin-O-dealkylation
    G Blaich
    Institute of Toxicology and Pharmacology,
    Chem Biol Interact 67:129-38. 1988
    ..hydrocarbon hydroxylase (AHH) were measured in hepatic microsomes from male and female Wistar rats and Syrian golden hamsters in order to probe the basal activity and the inducibility by phenobarbital (PB) and 3-methylcholanthrene (..
  55. pmc In vivo kinetics and spectra of 5-aminolaevulinic acid-induced fluorescence in an amelanotic melanoma of the hamster
    C Abels
    Institute for Surgical Research, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Br J Cancer 70:826-33. 1994
    ..were performed in the amelanotic melanoma A-Mel-3 grown in the dorsal skinfold chamber preparation of Syrian golden hamsters. The kinetics of fluorescent porphyrins was quantified up to 24 h after i.v...
  56. ncbi Distribution of hypocretin-(orexin) immunoreactivity in the central nervous system of Syrian hamsters (Mesocricetus auratus)
    E M Mintz
    Department of Biological Sciences, One University Plaza, Youngstown State University, Youngstown, OH 44555, USA
    J Chem Neuroanat 21:225-38. 2001
    ..This study was designed to examine the distribution of hypocretin immunoreactivity in Syrian hamsters, as important differences in neuropeptide distribution between rats and hamsters have previously been ..
  57. ncbi Circadian clock resetting by sleep deprivation without exercise in Syrian hamsters: dark pulses revisited
    Ralph E Mistlberger
    Department of Psychology, Simon Fraser University, Burnaby, British Columbia, Canada
    J Biol Rhythms 17:227-37. 2002
    Circadian rhythms in Syrian hamsters can be phase shifted by procedures that stimulate wheel running ("exercise") in the mid-subjective day (the hamster's usual sleep period)...
  58. ncbi Effects of food deprivation on locomotor activity, plasma glucose, and circadian clock resetting in Syrian hamsters
    Ralph E Mistlberger
    Department of Psychology, Simon Fraser University, Burnaby, British Columbia, Canada
    J Biol Rhythms 21:33-44. 2006
    Circadian rhythms in Syrian hamsters can be phase advanced by activity or arousal stimulated during the daily rest phase ("subjective day"). A widely used method for stimulating activity is confinement to a novel wheel...
  59. ncbi Yellow fever virus isolated from a fatal post vaccination event: an experimental comparative study with the 17DD vaccine strain in the Syrian hamster (Mesocricetus auratus)
    Sueli Guerreiro Rodrigues
    Instituto Evandro Chagas, Belem, PA, Brasil
    Rev Soc Bras Med Trop 37:69-74. 2004
    ..a fatal adverse event after yellow fever virus (YFV) vaccination, an experimental assay using hamsters (Mesocricetus auratus) as animal model and YFV 17DD vaccine strain as virus reference was accomplished...
  60. ncbi Biochemical and immunochemical evidence for the induction of an ethanol-inducible cytochrome P-450 isozyme in male Syrian golden hamsters
    G D McCoy
    Department of Environmental Health Sciences, Case Western Reserve University, School of Medicine, Cleveland, OH 44106
    Biochem Pharmacol 37:1563-8. 1988
    ..This isozyme can be readily monitored by either high-affinity aniline or p-nitrophenol hydroxylation or by Western immunoblot analysis and appears to be the ethanol-inducible form of cytochrome P-450 in hamsters...
  61. ncbi The neurobehavioral effects of phytoestrogens in male Syrian hamsters
    Tim O Moore
    Neuroscience Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Brain Res 1016:102-10. 2004
    ..determine whether or not diet can have neurobehavioral effects on intermale aggression in Syrian hamsters (Mesocricetus auratus)...
  62. ncbi Okadaic acid potentiates 3-methylcholanthrene-induced CYP2A8 gene expression in primary cultures of Syrian hamster hepatocytes: possible involvement of activator protein-1
    M Tohkin
    Department of Pharmaceutical Sciences, National Institute of Public Health, Tokyo, Japan
    Mol Pharmacol 50:556-64. 1996
    In Syrian hamster liver, treatment with 3-methylcholanthrene (3-MC) markedly induces an isozyme of cytochrome P450 (CYP), CYP2A8...
  63. ncbi Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains
    Sander Herfst
    Department of Virology, Erasmus MC, Rotterdam, The Netherlands
    J Gen Virol 88:2702-9. 2007
    ..antigenicity, immunogenicity and protective efficacy of these soluble F subunit vaccines were evaluated in Syrian golden hamsters (Mesocricetus auratus)...
  64. pmc Mammalian aspartate transcarbamylase (ATCase): sequence of the ATCase domain and interdomain linker in the CAD multifunctional polypeptide and properties of the isolated domain
    J P Simmer
    Department of Biochemistry, Wayne State University, Detroit, MI 48201
    Proc Natl Acad Sci U S A 86:4382-6. 1989
    ..We have sequenced selected restriction fragments of a Syrian hamster CAD cDNA that are clearly homologous to three prokaryotic ATCases...
  65. ncbi Neuropeptide Y inhibits estrous behavior and stimulates feeding via separate receptors in Syrian hamsters
    E S Corp
    Center for Neuroendocrine Studies, Neuroscience and Behavior Program and Department of Psychology, Box 37720, University of Massachusetts Amherst, Amherst, MA 01003, USA
    Am J Physiol Regul Integr Comp Physiol 280:R1061-8. 2001
    Central injections of neuropeptide Y (NPY) increase food intake in Syrian hamsters; however, the effect of NPY on sexual behavior in hamsters is not known nor are the receptor subtypes involved in feeding and sexual behaviors...
  66. ncbi Mass spectrometric detection of attomole amounts of the prion protein by nanoLC/MS/MS
    Bruce Onisko
    Western Regional Research Center, United States Department of Agriculture, Albany, California, USA
    J Am Soc Mass Spectrom 18:1070-9. 2007
    ..The VVEQMCTTQYQK method has a LOD of 20 to 30 amol for pure standards. Proof of principle is demonstrated by quantitation of the amount of PrP 27-30 in the brains of terminally ill Syrian hamsters.
  67. pmc Clerodendron inerme protects cellular integrity during 7,12-dimethylbenz[A]-anthracene induced hamster buccal pouch carcinogenesis
    Shanmugam Manoharan
    Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar 608002, Tamil Nadu, India
    Afr J Tradit Complement Altern Med 5:213-22. 2008
    ..Oral squamous cell carcinoma was induced in the buccal pouch of Syrian golden hamsters by painting with 0.5% DMBA in liquid paraffin thrice a week for 14 weeks...
  68. ncbi Cloning of a mu-class glutathione S-transferase complementary DNA and characterization of its glucocorticoid inducibility in a smooth muscle tumor cell line
    J S Norris
    Department of Medicine, Medical University of South Carolina, Charleston 29425 2229
    Mol Endocrinol 5:979-86. 1991
    ..In contrast, cycloheximide treatment 3 h after glucocorticoid treatment resulted in nearly full induction. These results taken together suggest that hGSTYBX induction may be a secondary glucocorticoid response...
  69. ncbi Characterization of the 5' end of the growth-regulated Syrian hamster CAD gene
    P J Farnham
    McArdle Laboratory for Cancer Research, University of Wisconsin, Madison 53706
    Cell Growth Differ 1:179-89. 1990
    ..As a first step, the structure of the promoter region of the Syrian hamster CAD gene has been determined...
  70. ncbi Cloning of the p53 tumor suppressor gene from the Japanese medaka (Oryzias latipes) and evaluation of mutational hotspots in MNNG-exposed fish
    M K Krause
    Duke University Marine Laboratory, School of the Environment, Beaufort, NC 28516, USA
    Gene 189:101-6. 1997
    ..frog (Xenopus laevis), chicken (Gallus gallus), rat (Rattus norvegicus), mouse (Mus musculus), hamster (Mesocricetus auratus), green monkey (Ceropithecus aethiops) and human (Homo sapiens). A single 1...
  71. ncbi Unpredictable deprivation of water increases the probability of torpor in the Syrian hamster
    N Ibuka
    Department of Psychology, Shiga University, Shiga ken, Japan
    Physiol Behav 62:551-6. 1997
    The effect of unpredictable water deprivation on hibernation was investigated in the Syrian hamster under natural photoperiod and temperature...
  72. ncbi Aspects of mammalian spermatogenesis: electrophoretical analysis of protamines in mammalian species
    C H Lee
    Department of Medical Genetics, College of Medicine, Hanyang University, Seoul, Korea
    Mol Cells 9:556-9. 1999
    ..Microtus agretis, Apodemus flavicollis, Apodemus sylvaticus, Clethrionomys glareolus, the Chinese and the golden hamster. However, only one protamine is found in the spermatozoa of the guinea pig, dog, bull, black monkey, and the ..
  73. ncbi Increased expression of the gene for alpha-interferon-inducible protein in cardiomyopathic hamster heart
    E M Denovan-Wright
    Department of Pharmacology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, B3H 4H7, Canada
    Biochem Biophys Res Commun 267:103-8. 2000
    ..Thus, an inherited defect in CM hamsters leads to increased expression of p27-h in advance of the development of hypertrophy and heart failure...
  74. ncbi Serotonergic modulation of astrocytic activity in the hamster suprachiasmatic nucleus
    J D Glass
    Department of Biological Sciences, Kent State University, OH 44242, USA
    Neuroscience 94:1253-9. 1999
    ..receptor activation on the expression of glial fibrillary acidic protein in the suprachiasmatic nucleus of Syrian hamsters. Immunoblot and immunohistochemical procedures were used to examine the effects of systemic application of ..
  75. ncbi Regulation of intestinal apolipoprotein B mRNA editing levels by a zinc-deficient diet and cDNA cloning of editing protein in hamsters
    S K Reaves
    Department of Nutritional Sciences, University of Arizona, Tucson, AZ 85721, USA
    J Nutr 130:2166-73. 2000
    ..The influence of dietary zinc on intestinal apoB mRNA editing levels was examined in Golden Syrian hamsters (7 wk old) assigned to one of the following three dietary treatments: Zn-adequate (ZA, 30 mg Zn/kg diet), Zn-..
  76. ncbi Paracoccidioides brasiliensis isolated from armadillos is virulent to Syrian hamsters
    M T Peracoli
    Departamento de Microbiologia e Imunologia, Instituto de Biociencias, Universidade Estadual Paulista, Botucatu, Sao Paulo, Brazil
    Mycopathologia 148:123-30. 1999
    ..The results demonstrated that Pb-T recently isolated from an animal was more virulent than Pb-18. These differences between the two P. brasiliensis isolates may be indicators of virulence attenuation in this fungal species...
  77. ncbi Exotic photoperiods induce and entrain split circadian activity rhythms in hamsters
    M R Gorman
    Department of Psychology, University of California, San Diego, USA
    J Comp Physiol A 187:793-800. 2001
    ..Male Syrian hamsters previously maintained on a 14-h day and 10-h night were exposed to a second 5-h dark phase in the afternoon...
  78. ncbi Food deprivation inhibits estrous behavior in hormone-treated Syrian hamsters despite elevated estradiol levels
    Juli E Jones
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst 01003 7720, USA
    Horm Behav 41:316-20. 2002
    ..Ovariectomized Syrian hamsters given varying doses of estradiol benzoate (EB) and P were tested to determine whether increasing doses of sex ..
  79. ncbi Short days and exogenous melatonin increase aggression of male Syrian hamsters (Mesocricetus auratus)
    Aaron M Jasnow
    Center for Behavioral Neuroscience, Department of Psychology, Georgia State University, Atlanta, 30303, USA
    Horm Behav 42:13-20. 2002
    ..the effects of photoperiod and exogenous melatonin on resident-intruder aggression in male Syrian hamsters (Mesocricetus auratus)...
  80. ncbi Positional candidate approach for the gene responsible for benign adult familial myoclonic epilepsy
    Akira Sano
    Department of Neuropsychiatry, Ehime University School of Medicine, Shigenobu, Onsen gun, Ehime, Japan
    Epilepsia 43:26-31. 2002
    ..segments were well conserved, and its overall amino acids homology as compared with those of rat and golden hamster was 95.0% and 95.0%...
  81. ncbi Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters
    Carolyn A Buckley
    Dept of Biological Sciences, Lehigh Univ, 111 Research Dr, Bethlehem, PA 18015, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1021-9. 2003
    ..Thus it is interesting that Syrian hamsters fail to increase food intake after a period of food deprivation, despite a fall in plasma leptin ..
  82. ncbi Cholecystokinin reduces ethanol consumption in golden hamsters
    David Dibattista
    Brock University, Department of Psychology, St Catharines, Ontario, Canada L2S 3A1
    Alcohol 29:173-81. 2003
    In experimental conditions, golden hamsters (Mesocricetus auratus) avidly consume ethanol solutions...
  83. ncbi Inhibition of experimental tobacco carcinogen induced head and neck carcinogenesis
    Joel Schwartz
    American Health Foundation, Molecular Pathology Facility, Institute for Cancer Prevention, One Dana Road, Valhalla, NY 10595, USA
    Oral Oncol 40:611-23. 2004
    ..43 I.U./0.136 (microM/treatment) administered by gavages to Syrian hamsters (14 animals per group) using physiologic low doses, 5X/week...
  84. ncbi Recognition of competitors by male golden hamsters
    Aras Petrulis
    Department of Psychology, Cornell University, Ithaca, NY 14853, USA
    Physiol Behav 81:629-38. 2004
    b>Golden hamsters, like many animals, form dominant/subordinate relationships after aggressive encounters...
  85. ncbi Role of quorum sensing in the pathogenicity of Burkholderia pseudomallei
    Ricky L Ulrich
    Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, MD 21702 5011, USA
    J Med Microbiol 53:1053-64. 2004
    ..pseudomallei via inhalational exposure of BALB/c mice and intraperitoneal challenge of Syrian hamsters has not been reported. This investigation demonstrates that B...
  86. ncbi Efficacy of rabies biologics against new lyssaviruses from Eurasia
    Cathleen A Hanlon
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Viral and Rickettsial Zoonoses Branch, 1600 Clifton Road NE, Rabies Team, Atlanta, GA 30333, USA
    Virus Res 111:44-54. 2005
    ..e., Syrian hamsters and ferrets)...
  87. ncbi Comparative genomics of the sperm mitochondria-associated cysteine-rich protein gene
    Sabrina K Hawthorne
    Department of Biology, University of Massachusetts at Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA
    Genomics 87:382-91. 2006
    ....
  88. ncbi Dendritic pruning of the medial amygdala during pubertal development of the male Syrian hamster
    Julia L Zehr
    Neuroscience Program, Michigan State University, East Lansing, MI 48824, USA
    J Neurobiol 66:578-90. 2006
    ..In pre-, mid-, and late pubertal (21, 35, and 49 days of age) male Syrian hamsters, we examined neuronal structure in Me and protein levels of spinophilin and synaptophysin in the amygdaloid ..
  89. ncbi Protective effect of Amomi semen extract on alloxan-induced pancreatic beta-cell damage
    Ji Hyun Lee
    Department of Biochemistry, Medical School, Chonbuk National University, Jeonju, 561 756, Jeonbuk, Republic of Korea
    Phytother Res 22:86-90. 2008
    ..Amomi semen extract (ASE) on alloxan-induced pancreatic beta-cell damage was investigated in HIT T-15 cells, a Syrian hamster pancreatic beta-cell line...
  90. ncbi Immunoglobulin M-enriched human intravenous immunoglobulins reduce leukocyte-endothelial cell interactions and attenuate microvascular perfusion failure in normotensive endotoxemia
    Johannes N Hoffman
    Department of Surgery, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Shock 29:133-9. 2008
    ..Male Syrian golden hamsters 6 to 8 weeks old with a body weight of 60 to 80 g were investigated by intravital fluorescence microscopy...
  91. doi Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate
    Kamala Pant
    Genetic Toxicology Department, BioReliance, Rockville, MD 20850, United States
    Mutat Res 654:108-13. 2008
    The Syrian hamster embryo (SHE) cell transformation assay has traditionally been conducted with a feeder layer of X-ray irradiated cells to provide growth support to the target cells seeded in low numbers...
  92. doi Hamster zona pellucida is formed by four glycoproteins: ZP1, ZP2, ZP3, and ZP4
    M J Izquierdo-Rico
    Department of Cell Biology, School of Medicine, University of Murcia, 30100 Murcia, Spain
    J Proteome Res 8:926-41. 2009
    ..In the hamster (Mesocricetus auratus), it was previously described that ZP was composed of three different glycoproteins, called ZP1, ZP2, and ..
  93. doi Attenuating effect of taurine on lipopolysaccharide-induced acute lung injury in hamsters
    Tapan M Bhavsar
    Department of Pharmaceutical Sciences, St John s University, Jamaica, NY 11439, USA
    Pharmacol Res 60:418-28. 2009
    ..02mg in phosphate buffered saline (PBS) pH 7.4) was instilled intratracheally into female Golden Syrian hamsters, before or after a 3-day intraperitoneal treatment with a single dose (50mg/kg in PBS pH 7.4) of taurine...
  94. pmc Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model
    Debanjan Dhar
    Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, USA
    Mol Ther 17:1724-32. 2009
    We have used Syrian hamsters to examine the role of pre-existing immunity to adenovirus (Ad) 5 in the toxicity of the oncolytic Ad vector INGN 007. Groups of hamsters were or were not immunized with Ad5...
  95. pmc Recombinant prion protein induces a new transmissible prion disease in wild-type animals
    Natallia Makarava
    Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
    Acta Neuropathol 119:177-87. 2010
    ..Here, we report that prion infectivity was generated in Syrian hamsters after inoculating full-length rPrP that had been converted into the cross-beta-sheet amyloid form and ..
  96. doi High-resolution mapping of interstitial telomeric repeats in Syrian hamster metaphase chromosomes
    S Demin
    Institute of Cytology, Russian Academy of Sciences, St Petersburg, Russia
    Cytogenet Genome Res 132:151-5. 2011
    Karyotype analysis of the Syrian hamster (Mesocricetus auratus) was performed after DAPI-banding of metaphase chromosomes obtained from cultivated skin fibroblasts of a newborn animal...
  97. pmc The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation
    Jens T Stieler
    Department of Molecular and Cellular Mechanisms of Neurodegeneration, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany
    PLoS ONE 6:e14530. 2011
    ..phosphorylation in various brain regions of three species of hibernating mammals: arctic ground squirrels, Syrian hamsters and black bears...
  98. doi Glutamate-vasopressin interactions and the neurobiology of anabolic steroid-induced offensive aggression
    M Carrillo
    Behavioral Neuroscience Program, Department of Psychology, 125 Nightingale Hall, Northeastern University, 360 Huntington Avenue, Boston, MA 02155, USA
    Neuroscience 185:85-96. 2011
    ..The current set of studies used male Syrian hamsters exposed to AAS during adolescence to examine whether increased glutamate-mediated stimulation of the BNST is ..
  99. doi Beneficial effects of cordycepin on metabolic profiles of liver and plasma from hyperlipidemic hamsters
    Yang Sun
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Asian Nat Prod Res 13:534-46. 2011
    ..a natural monomer compound, on endogenous metabolic profiles of liver and plasma from hyperlipidemic Syrian golden hamsters. Hyperlipidemia was successfully established in hamsters fed by a high-fat diet for 2 weeks...
  100. ncbi Presence of amastigotes in the central nervous system of hamsters infected with Leishmania sp
    Elisangela de Oliveira
    Laboratorio de Parasitologia, Departamento de Patologia, Centro de Ciencias Biologicas e da Saude, Faculdade de Medicina, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil
    Rev Bras Parasitol Vet 20:97-102. 2011
    ..Parasitological and immunohistochemical studies were performed golden hamsters Mesocricetus auratus infected with bone marrow from individuals with VL in the State of Mato Grosso do Sul, central-west Brazil...
  101. doi Comparative histopathology of Opisthorchis felineus and Opisthorchis viverrini in a hamster model: an implication of high pathogenicity of the European liver fluke
    Maria N Lvova
    Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, pr Akad Lavrent eva 10, Novosibirsk 630090, Russia
    Parasitol Int 61:167-72. 2012
    ..The study was conducted in 3 groups of 105 Syrian golden hamsters; the first and second groups fed with 50 metacercariae of O. felineus (OF) or O...

Research Grants67

  1. Richard H Melloni; Fiscal Year: 2015
    ..In previous studies, we showed that pubertal male Syrian hamsters (Mesocricetus auratus) exposed to moderate doses of commonly used anabolic steroids display a high level of offensive aggression ..
  2. TASTE QUALITY REPRESENTATION IN THE SOLITARY NUCLEUS
    MARION FRANK; Fiscal Year: 1992
    ..first central relay for taste in mammals, is being studied anatomically and physiologically in the hamster (Mesocricetus auratus) ...
  3. TEMPORAL INTEGRATION OF PHOTOPERIODIC SIGNALS IN MAMMALS
    Michael Gorman; Fiscal Year: 2002
    ..Prior studies have examined responses of Siberian, Phodopus sungorus, and Syrian hamsters, Mesocricetus auratus, to static long and short day lengths of early summer and winter, respectively...
  4. Neurobiology of Social Behavior
    ELLIOTT ALBERS; Fiscal Year: 2005
    ..will investigate the neural and endocrine mechanisms that control social behavior in Syrian hamsters (Mesocricetus auratus)...
  5. TEMPORAL INTEGRATION OF PHOTOPERIODIC SIGNALS IN MAMMALS
    Michael R Gorman; Fiscal Year: 2010
    ..Studies in this area have examined responses of Siberian, Phodopus sungorus, and Syrian hamsters, Mesocricetus auratus, exposed to static long and short day lengths of early summer and winter, respectively...
  6. H Craig Heller; Fiscal Year: 2016
    ..Neuroanatomical studies have shown that the SCN innervates the MS of rats, mice, and golden hamsters, thus, we firmly believe that the functional relationship between the SCN and MS established in Siberian ..
  7. Circadian Biology at the Supra-Organismal Level
    William J Schwartz; Fiscal Year: 2013
    ..We have found that co-housing pairs of golden hamsters or female laboratory mice can result in a change in a circadian clock property (the free-running circadian ..
  8. Integrative Neurobiology of Social Processes
    S Marc Breedlove; Fiscal Year: 2013
    ..in rats, mice, and voles;dominance hierarchies in spotted hyenas;social modulation of puberty in rats, Syrian hamsters and Siberian hamsters;as well as mating behaviors in a variety of vertebrates...
  9. FAT CELL PROLIFERATION IN OBESITY--MODULATING FACTORS
    Roy Martin; Fiscal Year: 1999
    ..3) diet-induced obesity: high fat diet (HFD)-fed Wistar rats; 4) seasonal (photoperiod)-induced obesity: Syrian hamsters; and 5) hyperplastic model: Guinea pig...
  10. ENVIRONMENTAL CONTROL OF SEASONAL WEIGHT CYCLES
    George Wade; Fiscal Year: 1992
    ..When photoperiod falls below a critical value, as in the autumn, Syrian hamsters gain weight and fatten, whereas Djungarian hamsters lose weight, primarily adipose tissue...
  11. NEUROENDOCRINE MECHANISMS IN SEASONAL REPRODUCTION
    BRYANT BENSON; Fiscal Year: 1990
    b>Syrian hamsters are long-day seasonal breeders whose reproductive systems become quiescent in the short days of fall and winter...
  12. Neurobiology of Circadian Dysrhythmias
    WILLIAM SCHWARTZ; Fiscal Year: 2007
    ..Notable examples of this are some of the effects of constant light (LL) - "splitting" in golden hamsters and circadian rhythmicity in genetically-deficient mice - that dramatically reorganize the circadian system...
  13. Matthew A Cooper; Fiscal Year: 2014
    ..we will investigate the mechanisms controlling resistance to social stress using a social defeat model in Syrian hamsters, called conditioned defeat...
  14. SOCIOSEXUAL BEHAVIOR - CELLULAR BASIS OF HORMONE ACTION
    ROBERT MEISEL; Fiscal Year: 1993
    ..program is to study cellular mechanisms of hormone action on sexual and aggressive behaviors in female Syrian hamsters. It is proposed that aggression is an integral component of social behaviors of females in general, and that ..
  15. Preventing lethal hemorrhagic fever caused by hantaviruses by preserving endothel
    ALAN L MUELLER; Fiscal Year: 2012
    ..In this project, we would identify the most efficacious dose of Slit2N in treating HPS in Syrian hamsters. Once the optimal dose is identified, we will experiment with dose timing to determine how late in the course ..
  16. JAY WILLIAMS HOOPER; Fiscal Year: 2016
    ..90] efficacy testing. Our HPS animal model involves adult Syrian hamsters infected with ANDV...
  17. Preventing Human Prion Diseases - Inactivation of Prions
    Stanley B Prusiner; Fiscal Year: 2010
    ..We have determined that treatment with acidic SDS combined with autoclaving reduces the infectivity of Syrian hamster Sc237 and human sCJD prions by a factor of >106...
  18. Svend O Freytag; Fiscal Year: 2016
    ..Toxicity will be examined in C57BL/6 male mice and Syrian hamsters, the latter of which are permissive for human adenovirus replication...
  19. Viral determinants of hantavirus pulmonary disease in the hamster
    Charles F Fulhorst; Fiscal Year: 2010
    ..The results of recent studies suggest that the virulence of the New World hantaviruses in Syrian golden hamsters, as in humans, is dependent upon viral genetics...
  20. Replication-deficient rabies vectors against rabies infection
    James P McGettigan; Fiscal Year: 2012
    ..goal of this grant application to identify the most promising vector in small animal models [mice (Aim I) and Syrian hamsters, (Aim II)]...
  21. Evaluation of C. difficile Severity in Epidemiologic Studies &in Animal Models
    LAURIE R ARCHBALD-PANNONE; Fiscal Year: 2012
    ..BI CDAD;and (3) determine the effects of clinically isolated BI strains on disease and mortality in the Syrian hamster model and the effects of purified toxins associated with BI on secretion and histological changes in the ..
  22. Pubertal Organization of Brain and Behavior
    Cheryl L Sisk; Fiscal Year: 2012
    ..The proposed research uses a well-suited laboratory rodent model, the male Syrian hamster, to empirically test the hypothesis that the adolescent transition in social information processing is gonadal ..
  23. Effects of Clopazine and haloperidol on responding
    Danielle Gulick; Fiscal Year: 2010
    ..goals of this proposal are: (A) to begin to understand the factors underlying alcohol consumption in the Syrian golden hamster, an animal model with strong predictive validity for the ability of drugs to decrease alcohol abuse in ..
  24. Erich R Mackow; Fiscal Year: 2016
    ..ANDV infection of Syrian hamsters is the only animal model of hantavirus disease which closely mimics HPS, resulting in fatal acute pulmonary ..
  25. Spread of Replicating Adenovirus in Solid Tumors
    John Hay; Fiscal Year: 2009
    ..Recently, it has been reported that the human adenovirus will replicate in the Syrian Hamster making this an ideal model for safety and efficacy evaluation.
  26. Analysis of a new circadian mutant
    Michael Menaker; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): We have discovered a new spontaneous circadian mutation in Syrian hamsters, which confers a robust phenotype on the animals'locomotor rhythmicity...
  27. Design of CNS-targeted peptide entry inhibitors for emerging henipaviruses
    Anne Moscona; Fiscal Year: 2013
    ..Recently, we have successfully prevented and treated NiV infection in golden hamsters. Key to this success is the surprising finding from our biodistributio studies, that a single subcutaneous ..
  28. Development of genetic tools to study central Avp1b receptors
    HEATHER KINGSLEY CALDWELL; Fiscal Year: 2013
    ..and in which vasopressin is known to be important to the neural regulation of social behavior, specifically, Syrian hamsters and prairie voles...
  29. Design of peptide entry inhibitors and delivery systems to target emerging henipa
    Anne Moscona; Fiscal Year: 2010
    ..aim 1) will be tested for their ability to protect against infection with HeV and NiV infection in the golden hamster model of acute HeV/NiV infection. Treatment as well as pre- and post-exposure prophylaxis will be addressed...
  30. Conformational Conversions of Prion Protein
    Witold K Surewicz; Fiscal Year: 2013
    ..focused on: (i) determining the conformational structure of proteinase K- resistant form of the recombinant Syrian hamster prion protein, PrPres, obtained by brain PrPSc- templated protein misfolding cyclic amplification (PMCA) ..
  31. TUMOR CELL SYNTHESIS AND SECRETION OF PEPTIDE HORMONES
    David Orth; Fiscal Year: 1991
    ..Adult Syrian golden hamsters to which a systemic carcinogen, diethylnitrosamine (DEN), is administered will be studied to determine if ..
  32. BIOMARKERS OF NNK AND NNN METABOLISM IN HUMANS
    Peter Foiles; Fiscal Year: 1993
    ..NNK induces tumors of the lung, trachea and nasal cavity in Syrian golden hamsters; the lung, nasal cavity, liver an pancreas of F344 rats; and the lung in A.J mice...
  33. Syrian Hamster as a Permissive Model for Testing Anti-Adenovirus Drugs
    William Wold; Fiscal Year: 2007
    ..Based on these observations, we propose to use CP-immunosuppressed Syrian hamsters as a new animal model to evaluate the efficacy and toxicology of anti-Ad drugs on disseminated Ad infections ..
  34. BILE ACIDS AND HEPATOCELLULAR SIGNAL TRANSDUCTION
    Bernard Bouscarel; Fiscal Year: 1999
    ..The goal of the first aim proposed by the PI is to define, in the isolated Golden Syrian hamster hepatocyte model, the different pathways involved in the regulation of calcium homeostasis by bile acids...
  35. Transgenic porphyric Leishmania as suicidal live vaccines against leishmaniasis
    Kwang Poo Chang; Fiscal Year: 2007
    ..vivo data, indicative of protection via this scheme of vaccination against experimental kala-azar in the Syrian Golden hamster model...
  36. STUDIES ON SPERM FERTILIZING ABILITY
    Barry Bavister; Fiscal Year: 1993
    ..will use well-defined in vitro fertilization techniques to examine details of the regulatory mechanisms with golden hamster gametes...
  37. Rapid Screening Method: Gamma-hydroxybutyrate Detection
    Deborah Mash; Fiscal Year: 2002
    ..The GHB dehydrogenase of Syrian hamster liver, which has been purified and well characterized, will be used to evaluate the accuracy and reliability ..
  38. GLUCOSE METABOLISM EFFECTS ON REPRODUCTIVE BEHAVIOR
    JILL SCHNEIDER; Fiscal Year: 2000
    ..the caudal brain stem to the hypothalamic neurons suspected to be involved in pulsatile GnRH secretion in Syrian hamsters. Another set of experiments will examine the nature of metabolic signals by comparing the ability of ..
  39. ROLE OF ETHANOL IN THE ETIOLOGY OF HEAD & NECK CANCER
    G McCoy; Fiscal Year: 1992
    ..that enhanced metabolic activation of NPYR in target tissues results in enhanced carcinogenicity in Syrian golden hamsters and to critically examine the respective roles of alpha- and Beta-hydroxylation, and denitrosation in the ..
  40. PREVENTION OF ESTRADIOL-INDUCED TUMORS BY VITAMIN C
    JOACHIM LIEHR; Fiscal Year: 1991
    Co-administration of vitamin C to estrogen-treated Syrian hamsters significantly lowered the incidence of estradiol-induced renal tumors...
  41. NEURAL ANDROGEN RECEPTORS FACILITATING COPULATION
    Ruth Wood; Fiscal Year: 1999
    ..The Syrian hamster is an appropriate animal model for these studies beacuse the male is dependent upon both chemosensory stimuli ..
  42. MODULATION OF LIVER FLUKE-ASSOCIATED NEOPLASIA
    Nobuyuki Ito; Fiscal Year: 1990
    ..model closely mirroring the disease in man has already been established utilizing the susceptibility of Syrian golden hamsters to Opisthorchis viverrini and chemical carcinogens...
  43. ELECTROPHYSIOLOGY OF THE SENSORY SYSTEM
    James Rose; Fiscal Year: 1993
    ..response to lumbosacral tactile stimulation, by effects of estradiol and progesterone on the brain in female golden hamsters. Previous research has shown the lordosis- inducing effects of estradiol to be mediated principally through ..
  44. Hamster Models and Reagents for Biodefense Research
    Lynn Soong; Fiscal Year: 2004
    The Syrian golden hamster is highly susceptible to a variety of intracellular pathogens, and serves as an excellent model for these pathogens' corresponding human diseases...
  45. GENE MUTATIONS IN ESTROGEN-INDUCED CARCINOGENESIS
    JOACHIM LIEHR; Fiscal Year: 1999
    As part of our investigation of the mechanism of estradiol-induced renal carcinogenesis in male Syrian hamsters, we have demonstrated that c-fos expression in tumor cells is high and regulated by estrogen binding to its receptor, whereas ..
  46. ONCOGENES IN CARCINOGEN-INITIATED HAMSTER TUMOR CELLS
    Vicente Notario; Fiscal Year: 1993
    ..system for carcinogenesis which uses chemical and physical carcinogens both in vivo and in vitro to generate Syrian hamster cells with diverse levels of malignant transformation and tumorigenicity...
  47. Cytokine-Mediated Regulation of Cholesterogenesis
    Ishaiahu Shechter; Fiscal Year: 2005
    ..Aim 1 we will determine the effects of LPS and cytokines on hepatic SQS transcription and mRNA stability in Syrian hamsters fed with different cholesterogenic diets...
  48. LOCAL MECHANISMS OF ARTERIOLAR CONTROL IN EXERCISE
    INGRID SARELIUS; Fiscal Year: 2001
    ..The proposed studies will be undertaken in cremaster muscles of anesthetized Golden hamsters, using local stimulation of groups of muscle fibers underlying only capillaries, and observing remote ..
  49. Mechanisms of Amphetamine Action on Dopaminergic Signaling
    PAUL GARRIS; Fiscal Year: 2007
    ..The first aim will compare the stimulant effects of amphetamine in rats and Syrian hamsters. While separate studies suggest that Syrian hamsters are less sensitive to amphetamine than other rodents ..
  50. INVESTIGATIONS INTO SELECTIVITY AND MONITORING SYSTEMS
    Christopher Benz; Fiscal Year: 1990
    ..T47-D, pancreas MiaPaCa; colon HCT8), and two cultured rodent tumor lines ( rat pancreatic AR42j and Syrian golden hamster melanoma) both of which can be carried as implanted rodent tumors for concurrent in vivo study...
  51. CELLULAR METABOLISM OF AMYLOID PROTEINS IN AGING
    Barbara Schreiber; Fiscal Year: 1999
    ..The model of spontaneous AA amyloidosis in aging female golden Syrian hamsters is ideally suited for analysis of amyloidogenic factors in the absence of confounding factors due to the ..
  52. OXYGEN AFFINITY AND OXYGEN TRANSPORT IN STRIATED MUSCLE
    Mary Ellsworth; Fiscal Year: 1992
    ..Experiments will be performed on the cheek pouch retractor muscle of the golden hamster. Oxygen affinity will be determined by the position of the oxyhemoglobin dissociation curve assessed by ..
  53. CLONING OF THE HAMSTER TGF-ALPHA 3'UNTRANSLATED REGION
    TAO CHIANG; Fiscal Year: 1991
    ..We have recently cloned the DNA sequence encoding the mature TGF-alpha peptide as well as the 5'UTR from the Syrian hamster. Furthermore, we have found that the hamster TGF-alpha 3'UTR is about 1-kb larger than that of human and rat...
  54. FUNCTION OF THE PCPH ONCOGENE IN MAMM;CARCINOGENESIS
    Vicente Notario; Fiscal Year: 2007
    ..on the basis of its frequent detection as an activated oncogene (mt-PCPH) in chemically initiated, tumorigenic Syrian hamster embryo cells...
  55. PATHOPHYSIOLOGY OF MICROCIRCULATION IN HYPERTENSION
    WILLIAM JOYNER; Fiscal Year: 1990
    ..We have been inbreeding the golden Syrian hamster (Mesecricetus auratus) and we find that strains characterized by their phenotypic traits develop (8-12 wks) ..
  56. DEVELOPMENT OF THE MAMMALIAN VISUAL SYSTEM
    DOUGLAS FROST; Fiscal Year: 1990
    ..projections to auditory or somatosensory thalamic nuclei can be reliably produced by neurosurgery on newborn Syrian hamsters. Neurophysiological recording and the 2-deoxyglucose metabolic mapping techniques will be used to determine ..
  57. PGE2, G PROTEINS, AND INSULIN SECRETION
    Elizabeth Seaquist; Fiscal Year: 1993
    ..aims of the investigation are (1) to examine eicosanoid production in HIT cells and in islets isolated form Syrian hamsters and humans; (2) to determine whether cyclooxygenase and lipoxygenase inhibitors positively and negatively ..
  58. Hantavirus pathogenesis and prevention
    Colleen Jonsson; Fiscal Year: 2006
    ..A brief description of the model is as follows: adult Syrian hamsters injected with Andes virus (ANDV) (a hantavirus that causes the majority of HPS cases in South America) ..
  59. Insulin Signaling in the Anterior Pituitary
    MARK LAWSON; Fiscal Year: 2006
    ..Studies in animal model systems ranging from Syrian hamsters, rats, ewes and some clinical observations indicate that insulin can suppress pituitary reproductive hormone ..
  60. INFLUENCE OF PARTICULATES ON OCCUPATIONAL LUNG DISEASE
    David Warshawsky; Fiscal Year: 1992
    ..Male Syrian Golden hamsters (8-9 wk old) are known to be susceptible to the formation of lung tumors by PaP-coated particulates...
  61. Mechanisms of Cell Death in Cardiomyopathy
    TUAN KUO; Fiscal Year: 2004
    ..3. To study the development of cardiomyopathy in the Syrian hamster. The development of lesion in the myopathic heart will be followed at pre-necrotic- (1 mo), necrotic- (2 mo...
  62. MOLECULAR DETERMINANTS OF ORAL CARCINOGENESIS
    David Wong; Fiscal Year: 1992
    ..This is a five-year research grant application proposing to use the cheek pouch of the Syrian hamster as an experimental model for the molecular study of oral carcinogenesis...
  63. Mechanisms of Stress-Induced Changes in Behavior
    Matthew Cooper; Fiscal Year: 2006
    ..In male Syrian hamsters, a single social defeat produces a prolonged reduction in territorial aggression and a concomitant rise in ..
  64. AMELIORATION OF ORAL MUCOSITIS IN ANIMAL MODELS
    John Haley; Fiscal Year: 2000
    ..In Phase I we developed a robust animal model for radiation and combined chemotherapy/radiation in the Golden Syrian hamster. These models employed a fractionated radiation regimen to induce significant mucositis with little mortality ..
  65. PERIPHERAL GUSTATORY PROCESSING
    MARION ELIZABETH FRANK; Fiscal Year: 2010
    ..3 integrated behavioral, neurophysiological and genetic studies are proposed on golden hamsters (Mesocricetus auratus) and laboratory mice aimed at delineating the functioning of their sweet (attracting) and bitter (avoiding) ..

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