Genomes and Genes
Burkholderia mallei ATCC 23344
Alias: Burkholderia mallei str. ATCC 23344
- Requirement of DNA repair mechanisms for survival of Burkholderia cepacia G4 upon degradation of trichloroethyleneC M Yeager
Molecular and Cellular Biology Program, Oregon State University, Corvallis, Oregon 97331 2902, USA
Appl Environ Microbiol 67:5384-91. 2001..cepacia G4 cells to survive following TCE transformation. A possible role for nucleotide excision repair and recombination repair activities in TCE-damaged cells is discussed...
- Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutantJoanne M Stevens
Division of Microbiology, Institute for Animal Health, Compton Laboratory, Berkshire, UK
J Bacteriol 187:7857-62. 2005..pseudomallei bimA mutant. While the BimA homologs differ in their amino-terminal sequence, they interact directly with actin in vitro and vary in their ability to bind Arp3...
- Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hostsClaudia M Romero
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
BMC Genomics 7:228. 2006More than 12,000 simple sequence repeats (SSRs) have been identified in the genome of Burkholderia mallei ATCC 23344. As a demonstrated mechanism of phase variation in other pathogenic bacteria, these may function as mutable loci leading ..
- Identification of the acid phosphatase (acpA) gene homologues in pathogenic and non-pathogenic Burkholderia spp. facilitates TnphoA mutagenesisM Burtnick
Dept of Microbiology and Infectious Diseases, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada
Microbiology 147:111-20. 2001..Two such systems have been successfully utilized in Burkholderia spp. for the identification of several genes encoding exported proteins...
- Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanismsVesna Memisevic
Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U S Army Medical Research and Materiel Command, Fort Detrick, Maryland, United States of America
PLoS Comput Biol 11:e1004088. 2015..were shown to attenuate disease progression in an aerosol infection animal model using the virulent Burkholderia mallei ATCC 23344 strain. Here, we performed an extended analysis of primarily nine B...
- Acyl-ACP substrate recognition in Burkholderia mallei BmaI1 acyl-homoserine lactone synthaseAubrey N Montebello
Department of Chemistry and Biochemistry, Boise State University, 1910 University Drive, Boise, Idaho 83725, United States
Biochemistry 53:6231-42. 2014..These results offer insights into the molecular basis of substrate recognition for the BmaI1 enzyme. ..
- Characterization of an autotransporter adhesin protein shared by Burkholderia mallei and Burkholderia pseudomalleiEric R Lafontaine
Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, 30602 Athens, GA, USA
BMC Microbiol 14:92. 2014..In this study, we report the identification and characterization of a novel autotransporter gene product of Burkholderia mallei (locus tag BMA1027 in strain ATCC 23344)...
- Organization and localization of the dnaA and dnaK gene regions on the multichromosomal genome of Burkholderia multivorans ATCC 17616Yuji Nagata
Graduate School of Life Sciences, Tohoku University, 2 1 1 Katahira, Sendai 980 8577, Japan
J Biosci Bioeng 99:603-10. 2005..Pulsed-field gel electrophoresis and Southern blot analyses indicated that both the dnaA and dnaK gene regions exist as single copies on the 3.4 Mb chromosome...
- Type III secretion: a virulence factor delivery system essential for the pathogenicity of Burkholderia malleiRicky L Ulrich
Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702 5011, USA
Infect Immun 72:1150-4. 2004By creating mutations in the Burkholderia mallei ATCC 23344 animal pathogen-like type III secretion system (TTSS), this study analyzes the correlation between type III secretion and the pathogenicity of ATCC 23344 in vivo...
- mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei ATCC 23344Kyoung Hee Choi
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1682, USA
Nat Protoc 1:162-9. 2006..This first chromosome integration system in B. mallei provides an important contribution to the genetic tools emerging for Burkholderia spp. Vectors are available for gene complementation and expression, and gene fusion analyses...
- Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable markerSheryl L W Zajdowicz
Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America
PLoS ONE 6:e21523. 2011..pseudomallei K96243. In addition, the alanine racemase deficient mutant of B. pseudomallei K96243 exhibited attenuation versus its isogenic parental strain with respect to growth and survival in murine peritoneal macrophages...
- Type VI secretion is a major virulence determinant in Burkholderia malleiMark A Schell
Department of Microbiology, University of Georgia, Athens, GA 30602, USA
Mol Microbiol 64:1466-85. 2007..Purified His-tagged BMAA0742 was recognized by glanders antiserum from a horse, a human and mice, indicating that this Hcp-family protein is produced in vivo during infection...
- Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiHYu Wang
Department of Molecular Biosciences, The University of Kansas, 1200 Sunnyside Avenue, Lawrence, KA 66045, USA
J Mol Biol 371:1304-14. 2007..typhimurium and S. flexneri...
- Identification of a response regulator gene for catabolite control from a PCB-degrading beta-proteobacteria, Acidovorax sp. KKS102Yoshiyuki Ohtsubo
Department of Environmental Life Sciences, Graduate School of Life Sciences, 2 1 1 Katahira, Sendai 980 8577, Japan
Mol Microbiol 60:1563-75. 2006..The genes highly similar to bphQ were found from several beta-proteobacteria, such as Burkholderia cenocepacia J2315, B. multivorans ATCC17616, B. xenovorans LB400 and Ralstonia solanacearum RS1085...
- Application of a recA gene-based identification approach to the maize rhizosphere reveals novel diversity in Burkholderia speciesGeorge W Payne
Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK
FEMS Microbiol Lett 259:126-32. 2006....
- Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomalleiLingling Zhang
Department of Molecular Biosciences, The University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA
J Mol Biol 359:322-30. 2006....
- The SlyB outer membrane lipoprotein of Burkholderia multivorans contributes to membrane integrityMaria Plesa
Flanders Interuniversity Institute of Biotechnology VIB6, Laboratory of Microbial Interactions, Department of Molecular and Cellular Interactions, Vrije Universiteit Brussel, Building E, room 6 6, Pleinlaan 2, B 1050 Brussels, Belgium
Res Microbiol 157:582-92. 2006..Taken together, these phenotypes suggest that SlyB contributes to the integrity of the cell envelope. By PCR amplification we were also able to demonstrate the conservation of slyB in all B. cepacia complex species tested...
- A disruption of ctpA encoding carboxy-terminal protease attenuates Burkholderia mallei and induces partial protection in CD1 miceAloka B Bandara
Center for Molecular Medicine and Infectious Diseases, Virginia Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0342, USA
Microb Pathog 45:207-16. 2008..mallei ATCC 23344. These findings suggest that CtpA regulates in vitro growth, cell morphology and intracellular survival of B. mallei, and a ctpA mutant protects CD1 mice against glanders...
- Species abundance and diversity of Burkholderia cepacia complex in the environmentAlban Ramette
Center for Microbial Ecology, 540 Plant and Soil Sciences Building, Michigan State University, East Lansing, MI 48824 1325, USA
Appl Environ Microbiol 71:1193-201. 2005..cepacia complex species and closely related strains of the same species may coexist at high population levels but also species composition and abundance may dramatically vary between individual plants...
- Quorum sensing: a transcriptional regulatory system involved in the pathogenicity of Burkholderia malleiRicky L Ulrich
Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702, USA
Infect Immun 72:6589-96. 2004..An in silico analysis of the Burkholderia mallei ATCC 23344 genome revealed that it encodes at least two luxI and four luxR homologues...
- Polyphasic characterisation of Burkholderia cepacia-like isolates leading to the emended description of Burkholderia pyrrociniaVirginie Storms
Laboratory for Microbiology, Faculty of Sciences, University of Ghent, Ghent, Belgium
Syst Appl Microbiol 27:517-26. 2004..cepacia complex species thus far comprising one single soil isolate only. An emended description of Burkholderia pyrrocinia is proposed. The taxonomic status of the remaining two isolates requires further analysis...
- Structural flexibility in the Burkholderia mallei genomeWilliam C Nierman
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 101:14246-51. 2004The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. B...
- Proposal to accommodate Burkholderia cepacia genomovar VI as Burkholderia dolosa sp. novKaren Vermis
Laboratory for Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
Int J Syst Evol Microbiol 54:689-91. 2004..cepacia-selective medium PCAT. Both 16S rDNA and recA RFLP analysis revealed unique B. dolosa restriction patterns. In addition, new 16S rDNA- and recA-based PCR assays allowed its specific identification...
- Functional reconstitution, gene isolation and topology modelling of porins from Burkholderia pseudomallei and Burkholderia thailandensisJaruwan Siritapetawee
School of Biochemistry, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand
Biochem J 377:579-87. 2004..Topology prediction and molecular modelling suggest that this newly-isolated and cloned porin is a 16-stranded beta-barrel and the external loops of the protein could be important determinants of the immune response to infection...
- Burkholderia anthina sp. nov. and Burkholderia pyrrocinia, two additional Burkholderia cepacia complex bacteria, may confound results of new molecular diagnostic toolsPeter Vandamme
Laboratorium voor Microbiologie, Universiteit Gent, Ghent, Belgium
FEMS Immunol Med Microbiol 33:143-9. 2002..cepacia complex. This highlights another potential source for diagnostic problems with B. cepacia-like bacteria...
- Genetic organization and sequence of the Pseudomonas cepacia genes for the alpha and beta subunits of protocatechuate 3,4-dioxygenaseG J Zylstra
Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor 48109 0620
J Bacteriol 171:5915-21. 1989..The deduced amino acid sequence showed extensive homology with the previously determined amino acid sequence of protocatechuate 3,4-dioxygenase from another Pseudomonas species...
- Construction of a recA mutant of Burkholderia (formerly Pseudomonas), cepaciaL G van Waasbergen
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater 74078, USA
Appl Microbiol Biotechnol 49:59-65. 1998..cepacia and a recA mutant will be useful in bioengineering of this species...
- Characterization of genes involved in biosynthesis of a novel antibiotic from Burkholderia cepacia BC11 and their role in biological control of Rhizoctonia solaniY Kang
Department of Microbiology, University of Georgia, Athens, Georgia 30602, USA
Appl Environ Microbiol 64:3939-47. 1998..DNA sequence analysis suggested that this region encodes proteins directly involved in the production of a nonribosomally synthesized lipopeptide...
- PCR-RFLP analysis of the flagellin sequences for identification of Burkholderia pseudomallei and Burkholderia cepacia from clinical isolatesS Tungpradabkul
Faculty of Science, Mahidol University, Rama VI Rd, Bangkok, 10400, Thailand
Mol Cell Probes 13:99-105. 1999..cepacia, to enable flagellin-type identification on the basis of the pattern of restriction fragments. In addition, the flagellin gene should be of considerable use as a genetic marker for clinical identification of these organisms...
- Polyhydroxyalkanoate accumulation in Burkholderia sp.: a molecular approach to elucidate the genes involved in the formation of two homopolymers consisting of short-chain-length 3-hydroxyalkanoic acidsM F Rodrigues
Institut fur Mikrobiologie, Westfalische Wilhelms Universitat Munster, Germany
Appl Microbiol Biotechnol 53:453-60. 2000..The arrangement of the three genes is quite similar to the R. eutropha poly-beta-hydroxybutyrate biosynthesis operon...
- Cloning and characterisation of malE in Burkholderia pseudomalleiP C Woo
Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Hong Kong
J Med Microbiol 50:330-8. 2001..Further studies on serodiagnosis of melioidosis with recombinant MBP should be performed...
- Burkholderia ambifaria sp. nov., a novel member of the Burkholderia cepacia complex including biocontrol and cystic fibrosis-related isolatesT Coenye
Laboratorium voor Microbiologie, Universiteit Gent, Ghent, Belgium
Int J Syst Evol Microbiol 51:1481-90. 2001..cepacia complex would be ill-advised until more is known about their potential pathogenic mechanisms...
- Molecular and physical characterization of Burkholderia mallei O antigensMary N Burtnick
Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
J Bacteriol 184:849-52. 2002..pseudomallei O polysaccharide (O-PS). In this study, we identified the O-PS biosynthetic gene cluster from B. mallei ATCC 23344 and subsequently characterized the molecular structure of the O-PS produced by this organism...
- Role of flagella in host cell invasion by Burkholderia cepaciaMladen Tomich
Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455 0312, USA
Infect Immun 70:1799-806. 2002..cepacia. Our findings indicate that flagellum-mediated motility may facilitate penetration of host epithelial barriers by B. cepacia, contributing to establishment of infection and systemic spread of the organism...
- Cloning, sequencing, and transcriptional analysis of the recA gene of Pseudomonas cepaciaT Nakazawa
Department of Microbiology, Yamaguchi University School of Medicine, Japan
Gene 94:83-8. 1990..An SOS box characteristic to LexA-regulated promoters, along with the -10 and -35 consensus sequences, was found in the 5' upstream region of the P. cepacia recA gene...
- Burkholderia cepacia complex infection in patients with cystic fibrosisEshwar Mahenthiralingam
Cardiff School of Biosciences, Cardiff University, Wales, UK
J Med Microbiol 51:533-8. 2002..For microbiologists, hospital infection control officers, caregivers, and most of all the CF community, the changes in our understanding of the taxonomy, epidemiology and pathogenesis of the bacterium 'B. cepacia' are complex...
- Characterization of a laboratory-generated variant of BPS beta-lactamase from Burkholderia pseudomallei that hydrolyses ceftazidimeP L Ho
Department of Microbiology and HKU Pasteur Research Centre, Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong SAR, China
J Antimicrob Chemother 50:723-6. 2002..coli conferred resistance to ceftazidime (MIC >or= 32 mg/L). The amino acid sequence of BPS-1m differed from that of BPS-1 by a Pro-to-Ser change at position 167 in the omega loop...
- Cloning and expression of the gene encoding catalytic subunit of thermostable glucose dehydrogenase from Burkholderia cepacia in Escherichia coliKen Inose
Department of Biotechnology, Tokyo University of Agriculture and Technology, 2 24 16 Naka machi, Tokyo Koganei 184 8588, Japan
Biochim Biophys Acta 1645:133-8. 2003..The deduced primary structure of gamma subunit showed about 30% identity to the small subunits of the SDH from G. oxydans and 2KGDHs from E. herbicola and P. citrea...
- Quorum-sensing system and stationary-phase sigma factor (rpoS) of the onion pathogen Burkholderia cepacia genomovar I type strain, ATCC 25416Claudio Aguilar
Bacteriology Group, International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34012 Trieste, Italy
Appl Environ Microbiol 69:1739-47. 2003..cepacia has a negative effect on rpoS expression as determined by using an rpoS-lacZ transcriptional fusion; on the other hand, rpoS-null mutants displayed no difference in the accumulation of HSL signal molecules...
- Burkholderia pseudomallei class a beta-lactamase mutations that confer selective resistance against ceftazidime or clavulanic acid inhibitionChanwit Tribuddharat
Department of Microbiology, Mahidol University, Bangkok 10700, Thailand
Antimicrob Agents Chemother 47:2082-7. 2003..pseudomallei penA gene revealed a putative regulator gene located downstream of penA. We have cloned and sequenced the penA gene from B. mallei and found it to be identical to penA from B. pseudomallei...
- Development of a species-specific recA-based PCR test for Burkholderia fungorumChun Han Chan
Department of Biological Sciences, Imperial College London, Sir Alexander Fleming Building, Imperial College Road, London SW7 2AZ, UK
FEMS Microbiol Lett 224:133-8. 2003..Using a similar procedure we extended the recA-based PCR assay to identify B. sacchari and B. caledonica, two additional soil-inhabiting Burkholderia spp...
- Seronegative bacteremic melioidosis caused by Burkholderia pseudomallei with ambiguous biochemical profile: clinical importance of accurate identification by 16S rRNA gene and groEL gene sequencingPatrick C Y Woo
Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
J Clin Microbiol 41:3973-7. 2003..Sequencing of the groEL gene showed that the isolate was B. pseudomallei. Proper identification of the bacterium in this study is crucial, since there would be a radical difference in the duration of antimicrobial therapy...
- Molecular typing of, and distribution of genetic markers among, Burkholderia cepacia complex isolates from BrazilMaria G Detsika
Department of Medical Microbiology and Genitourinary Medicine, University of Liverpool, Liverpool L69 3GA, United Kingdom
J Clin Microbiol 41:4148-53. 2003..Nine genomovar IIIA isolates from different non-CF patients and clinical sources had identical genotypes, indicating the presence of a common clone...
- Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharidesMiguel A Valvano
Department of Microbiology and Immunology and Medicine, University of Western Ontario, London, Ontario, N6A 5C1, Canada
Microbiology 148:1979-89. 2002
- The Transcriptome of Pathogenic Aspergillus FumigatusWilliam Nierman; Fiscal Year: 2003..abstract_text> ..
- Adherence mechanisms of Moraxella catarrhalisERIC LAFONTAINE; Fiscal Year: 2007..catarrhalis adhesins to determine whether they elicit the production of biologically relevant antibodies. Our studies will have direct applications in vaccine as well as antimicrobial development. ..
- Microarray Expression Analysis of Burkholderia MalleiWilliam Nierman; Fiscal Year: 2003..Function and virulence validation of the identified virulence genes will be explored by construction and phenotype analysis of targeted knockout strains. ..
- Regulation of Burkholderia mallei virulence genesWilliam Nierman; Fiscal Year: 2005..It will provide critical information on virulence control and virulence mechanisms of B. mallei and will be crucial to the development of effective therapeutic interventions and vaccine strategies. ..
- Host-Pathogen Interactions in Invasive AspergillosisWILLIAM CHARLES NIERMAN; Fiscal Year: 2010..necessary to maintain protective immunity against the invading fungus. This hithertn inaccessible ... in order to >.E =.m m'- N'3 ..' 'C3 _.n '-' a.. m._ o'< m- ..
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