Listeria monocytogenes EGD-e

Summary

Alias: Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e

Top Publications

  1. ncbi Species specificity of the Listeria monocytogenes InlB protein
    Nadia Khelef
    Institut Pasteur, Unité des Interactions Bactéries Cellules, 25 28 Rue du Docteur Roux, Paris, F 75015 France
    Cell Microbiol 8:457-70. 2006
  2. pmc Dependence of continuous-flow biofilm formation by Listeria monocytogenes EGD-e on SOS response factor YneA
    Stijn van der Veen
    Top Institute Food and Nutrition TIFN, Nieuwe Kanaal 9A, 6709 PA Wageningen, The Netherlands
    Appl Environ Microbiol 76:1992-5. 2010
  3. pmc Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes
    M Leimeister-Wächter
    Institut fur Genetik und Mikrobiologie, Universitat Wurzburg, Federal Republic of Germany
    Proc Natl Acad Sci U S A 87:8336-40. 1990
  4. ncbi Characterization of two putative Listeria monocytogenes genes encoding polypeptides homologous to the sensor protein CheA and the response regulator CheY of chemotaxis
    L Dons
    Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    DNA Seq 4:301-11. 1994
  5. ncbi Molecular characterization of an autolytic amidase of Listeria monocytogenes EGD
    A M McLaughlan
    Department of Molecular Biology, University of Sheffield, UK
    Microbiology 144:1359-67. 1998
  6. pmc General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes
    M Wiedmann
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, USA
    J Bacteriol 180:3650-6. 1998
  7. pmc Identification and characterization of an ATP binding cassette L-carnitine transporter in Listeria monocytogenes
    K R Fraser
    Department of Molecular and Cell Biology, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland
    Appl Environ Microbiol 66:4696-704. 2000
  8. pmc Characterization of the groESL operon in Listeria monocytogenes: utilization of two reporter systems (gfp and hly) for evaluating in vivo expression
    C G Gahan
    Department of Microbiology and National Food Biotechnology Centre, University College Cork, Ireland
    Infect Immun 69:3924-32. 2001
  9. ncbi Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes
    Eric Abachin
    Laboratoire de Microbiologie, INSERM U 411, Paris, France
    Mol Microbiol 43:1-14. 2002
  10. pmc Identification of Listeria monocytogenes genes expressed in response to growth at low temperature
    Siqing Liu
    Microbiology Group, Department of Biological Sciences, Illinois State University, Normal, Illinois 61790 4120, USA
    Appl Environ Microbiol 68:1697-705. 2002

Research Grants

Patents

  1. Plants with increased tolerance and/or resistance to environmental stress and increased biomass production
  2. Plants with increased yield
  3. Plants with increased yield
  4. Lipid metabolism proteins, combinations of lipid metabolism proteins and uses thereof
  5. Process for the production of lutein
  6. Method for producing a transgenic plant cell, a plant or a part thereof with increased resistance biotic stress
  7. Plants with increased yield (nue)
  8. Process for the production of fine chemicals
  9. Process for the control of production of fine chemicals
  10. Proteins associated with abiotic stress response and homologs

Scientific Experts

Detail Information

Publications132 found, 100 shown here

  1. ncbi Species specificity of the Listeria monocytogenes InlB protein
    Nadia Khelef
    Institut Pasteur, Unité des Interactions Bactéries Cellules, 25 28 Rue du Docteur Roux, Paris, F 75015 France
    Cell Microbiol 8:457-70. 2006
    ..These results unravel a second L. monocytogenes species specificity critical for understanding human listeriosis and emphasize the need for developing new animal models for studying InlA and InlB functions in the same animal model...
  2. pmc Dependence of continuous-flow biofilm formation by Listeria monocytogenes EGD-e on SOS response factor YneA
    Stijn van der Veen
    Top Institute Food and Nutrition TIFN, Nieuwe Kanaal 9A, 6709 PA Wageningen, The Netherlands
    Appl Environ Microbiol 76:1992-5. 2010
    ..Here we show that the SOS response is activated under these conditions and that deletion of its regulon member yneA results in diminished biofilm formation under continuous-flow conditions...
  3. pmc Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes
    M Leimeister-Wächter
    Institut fur Genetik und Mikrobiologie, Universitat Wurzburg, Federal Republic of Germany
    Proc Natl Acad Sci U S A 87:8336-40. 1990
    ..monocytogenes strain EGD. We have designated the gene encoding the 27-kDa polypeptide prfA, for positive regulatory factor of listeriolysin (lisA) expression. The prfA gene regulates transcription of the lisA gene positively...
  4. ncbi Characterization of two putative Listeria monocytogenes genes encoding polypeptides homologous to the sensor protein CheA and the response regulator CheY of chemotaxis
    L Dons
    Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    DNA Seq 4:301-11. 1994
    ..monocytogenes and consequently the putative genes are named cheY and cheA. Northern blot and primer extension analysis suggested that cheY and cheA are transcribed as a bicistronic unit and that the transcription is thermoregulated...
  5. ncbi Molecular characterization of an autolytic amidase of Listeria monocytogenes EGD
    A M McLaughlan
    Department of Molecular Biology, University of Sheffield, UK
    Microbiology 144:1359-67. 1998
    ..Characterization of the recombinant enzyme expressed in Escherichia coli has revealed it to be an amidase and to be able to hydrolyse a range of peptidoglycan substrates...
  6. pmc General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes
    M Wiedmann
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, USA
    J Bacteriol 180:3650-6. 1998
    ..Our results suggest that sigmaB-directed genes do not appear to be essential for the spread of L. monocytogenes to mouse liver or spleen at 2 and 4 days following intragastric or intraperitoneal infection...
  7. pmc Identification and characterization of an ATP binding cassette L-carnitine transporter in Listeria monocytogenes
    K R Fraser
    Department of Molecular and Cell Biology, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland
    Appl Environ Microbiol 66:4696-704. 2000
    ..We conclude that the opuC operon in L. monocytogenes encodes an ABC compatible solute transporter which is capable of transporting L-carnitine and which plays an important role in osmoregulation in this pathogen...
  8. pmc Characterization of the groESL operon in Listeria monocytogenes: utilization of two reporter systems (gfp and hly) for evaluating in vivo expression
    C G Gahan
    Department of Microbiology and National Food Biotechnology Centre, University College Cork, Ireland
    Infect Immun 69:3924-32. 2001
    ..In this strain hemolysin expression during infection also confirms transcription from the groESL promoter during J774 and murine infection, albeit at lower levels than the known virulence factor plcA...
  9. ncbi Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes
    Eric Abachin
    Laboratoire de Microbiologie, INSERM U 411, Paris, France
    Mol Microbiol 43:1-14. 2002
    ..These results show that the D-alanylation of the LTAs contributes to the virulence of the intracellular pathogen L. monocytogenes...
  10. pmc Identification of Listeria monocytogenes genes expressed in response to growth at low temperature
    Siqing Liu
    Microbiology Group, Department of Biological Sciences, Illinois State University, Normal, Illinois 61790 4120, USA
    Appl Environ Microbiol 68:1697-705. 2002
    ....
  11. ncbi Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin
    Wolf Dieter Schubert
    Department of Structural Biology, German Research Center for Biotechnology GBF, Mascheroder Weg 1, D 38124, Braunschweig, Germany
    Cell 111:825-36. 2002
    ..monocytogenes infection that is essential for intermolecular recognition. Our studies reveal the structural basis for host tro-pism of this bacterium and the molecular deception L. monocytogenes employs to exploit the E-cadherin system...
  12. pmc CesRK, a two-component signal transduction system in Listeria monocytogenes, responds to the presence of cell wall-acting antibiotics and affects beta-lactam resistance
    Birgitte H Kallipolitis
    Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK 5230 Odense M, Denmark
    Antimicrob Agents Chemother 47:3421-9. 2003
    ..These results further our understanding of how L. monocytogenes senses and responds to antibiotics that are used therapeutically in the treatment of infectious diseases...
  13. pmc Listeria monocytogenes regulates flagellar motility gene expression through MogR, a transcriptional repressor required for virulence
    ANGELIKA GRUNDLING
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:12318-23. 2004
    ..These studies indicate that regulation of flagellar motility gene expression and/or other genes controlled by MogR is required for full virulence of L. monocytogenes...
  14. ncbi The Dps-like protein Fri of Listeria monocytogenes promotes stress tolerance and intracellular multiplication in macrophage-like cells
    Katja N Olsen
    Department of Veterinary Pathobiology, Royal Veterinary and Agricultural University KVL, Stigbøjlen 4, DK 1870 Frederiksberg C, Denmark
    Microbiology 151:925-33. 2005
    ..A1 mouse macrophage cells. Thus, the data suggest that Fri contributes to the ability of L. monocytogenes to survive in environments where oxidative stress and low iron availability may impede bacterial proliferation...
  15. pmc Role for HtrA in stress induction and virulence potential in Listeria monocytogenes
    Helena M Stack
    Department of Microbiology and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Appl Environ Microbiol 71:4241-7. 2005
    ..Our findings suggest that L. monocytogenes lmo0292 encodes an HtrA-like serine protease that is not part of the classical heat shock response but is involved in stress responses and virulence...
  16. ncbi Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence
    Olivier Dussurget
    Unité des Interactions Bactéries Cellules, INSERM U604, INRA USC2020, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
    FEMS Microbiol Lett 250:253-61. 2005
    ..A comparative proteomic analysis revealed an effect of the fri deletion on the levels of listeriolysin O and several stress proteins. Together, our study demonstrates that fri has multiple roles that contribute to Listeria virulence...
  17. pmc Simultaneous deficiency of both MurA and p60 proteins generates a rough phenotype in Listeria monocytogenes
    Silke Machata
    Institut fur Medizinische Mikrobiologie, Justus Liebig Universitat, Frankfurter Strasse 107, D 35392 Giessen, Germany
    J Bacteriol 187:8385-94. 2005
    ..monocytogenes. We also identified homologous MurA and SecA2 proteins in other Listeria species. The muramidase in two species, L. innocua and L. welshimeri, shows activity similar to that of the MurA protein in L. monocytogenes...
  18. pmc Tolerance of Listeria monocytogenes to cell envelope-acting antimicrobial agents is dependent on SigB
    Maire Begley
    Department of Microbiology and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Appl Environ Microbiol 72:2231-4. 2006
    ..SigB may therefore represent an attractive target for the development of new control and treatment strategies for this important pathogen...
  19. pmc Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis
    Iharilalao Dubail
    Faculte de Medecine Necker, 156, rue de Vaugirard, 75730 Paris Cedex 15, France
    J Bacteriol 188:6580-91. 2006
    ..monocytogenes that is involved in teichoic acid biogenesis. In vivo, the conditional mutant is very rapidly eliminated from the target organs of infected mice and thus is totally avirulent...
  20. pmc Agr system of Listeria monocytogenes EGD-e: role in adherence and differential expression pattern
    Aurélie Rieu
    UMR 1229 Microbiologie du Sol et de l Environnement, Universite de Bourgogne, INRA, F 21000 Dijon, France
    Appl Environ Microbiol 73:6125-33. 2007
    ....
  21. pmc Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin
    Thomas Wollert
    Molecular Host Pathogen Interactions, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D 38124 Braunschweig, Germany
    Proc Natl Acad Sci U S A 104:13960-5. 2007
    ..One such pair of single substitutions improves affinity 5,000-fold. We thus demonstrate that rational reengineering of protein complexes is possible by making use of physically distant hot spots of recognition...
  22. pmc Chitin hydrolysis by Listeria spp., including L. monocytogenes
    J J Leisner
    Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Grønnegårdsvej 15, 1870 Frederiksberg C, Denmark
    Appl Environ Microbiol 74:3823-30. 2008
    ..The chiB and chiA genes are phylogenetically related to various well-characterized chitinases. The potential biological implications of chitinolytic activity of Listeria are discussed...
  23. doi Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis
    Olivier Disson
    Institut Pasteur, Groupe Microorganismes et Barrières de l Hôte, Unité des Interactions Bactéries Cellules, F 75015 Paris, France
    Nature 455:1114-8. 2008
    ....
  24. pmc The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis
    Nicolas Personnic
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris F 75015, France
    Infect Immun 78:1979-89. 2010
    ..These results strongly suggest that InlH is a stress-induced surface protein that facilitates pathogen survival in tissues by tempering the inflammatory response...
  25. pmc Identification of the full set of Listeria monocytogenes penicillin-binding proteins and characterization of PBPD2 (Lmo2812)
    Dorota Korsak
    Institute of Microbiology, University of Warsaw, Miecznikowa 1, 02 096 Warsaw, Poland
    BMC Microbiol 10:239. 2010
    ..Here we report the positive identification of the full set of L. monocytogenes PBPs and the characteristics of the hitherto undescribed PBPD2 (Lmo2812)...
  26. ncbi Cloning and characterization of a gene encoding flagellin of Listeria monocytogenes
    L Dons
    Department of Molecular Food Technology, Biotechnological Institute, Lyngby, Denmark
    Mol Microbiol 6:2919-29. 1992
    ..monocytogenes can be divided into two groups. These groups correspond to the flagellar antigens AB and ABC, respectively, as well as to the two types of L. monocytogenes based on the DNA sequence of the listeriolysin gene...
  27. ncbi Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci
    J L Gaillard
    Laboratoire de Microbiologie, Faculte de Medecine Necker Enfants Malades, Paris, France
    Cell 65:1127-41. 1991
    ..As evidenced by Southern blot analysis, inlA is part of a gene family. One of them is the gene situated directly downstream of inlA, called inlB, which also encodes a leucine-rich repeat protein...
  28. pmc Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by M3
    L L Lenz
    Department of Immunology, University of Washington, Seattle, 98195, USA
    Immunity 5:63-72. 1996
    ....
  29. ncbi InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association
    L Braun
    Unité des Interactions Bactéries Cellules, Institut Pasteur, Paris, France
    Mol Microbiol 25:285-94. 1997
    ..This motif may have important consequences for the release of surface proteins involved in interactions with eukaryotic cells...
  30. pmc Identification of the gene encoding the alternative sigma factor sigmaB from Listeria monocytogenes and its role in osmotolerance
    L A Becker
    Department of Food Science and Technology, University of Nebraska, Lincoln, Nebraska 68583 0919, USA
    J Bacteriol 180:4547-54. 1998
    ..Thus, sigmaB coordinates responses to a variety of physical and chemical signals, and its function facilitates the growth of L. monocytogenes under conditions of high osmotic strength...
  31. ncbi Characterization of DegU, a response regulator in Listeria monocytogenes, involved in regulation of motility and contributes to virulence
    Gitte M Knudsen
    Department of Veterinary Pathobiology and Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Stigbøjlen 4, DK 1870 Frederiksberg C, Denmark
    FEMS Microbiol Lett 240:171-9. 2004
    ..The results indicate that the putative DegU response regulator is a pleiotropic regulator involved in expression of both motility at low temperature and in vivo virulence in mice...
  32. pmc Assessment of the roles of LuxS, S-ribosyl homocysteine, and autoinducer 2 in cell attachment during biofilm formation by Listeria monocytogenes EGD-e
    Sylvain Challan Belval
    Laboratoire de Microbiologie, UMR INRA UB 1232, ENSBANA, 1 Esplanade Erasme, 21000 Dijon, France
    Appl Environ Microbiol 72:2644-50. 2006
    ....
  33. doi Gene transcription and virulence potential of Listeria monocytogenes strains after exposure to acidic and NaCl stress
    Inger Olesen
    Department of Food Science, University of Copenhagen, Frederiksberg C, Denmark
    Foodborne Pathog Dis 6:669-80. 2009
    ..monocytogenes...
  34. doi Comprehensive appraisal of the extracellular proteins from a monoderm bacterium: theoretical and empirical exoproteomes of Listeria monocytogenes EGD-e by secretomics
    Mickael Desvaux
    INRA, UR454 Microbiology, Food Quality and Safety Team, Saint Genès Champanelle, France
    J Proteome Res 9:5076-92. 2010
    ..The novel and rational strategy described here is generic and has been purposely designed for the prediction of proteins localized extracellularly in monoderm bacteria...
  35. pmc Temporal transcriptomic analysis of the Listeria monocytogenes EGD-e sigmaB regulon
    Torsten Hain
    Institute for Medical Microbiology, Justus Liebig University, Frankfurter Strasse 107, D 35392 Giessen, Germany
    BMC Microbiol 8:20. 2008
    ..monocytogenes EGD-e. Whole genome-based transcriptional profiling was used to identify sigmaB-dependent genes at different growth phases...
  36. doi sigB absence decreased Listeria monocytogenes EGD-e heat resistance but not its Pulsed Electric Fields resistance
    M Somolinos
    Tecnologia de los Alimentos, Universidad de Zaragoza, C Miguel Servet 177, 50013 Zaragoza, Spain
    Int J Food Microbiol 141:32-8. 2010
    ....
  37. doi Interactions in dual species biofilms between Listeria monocytogenes EGD-e and several strains of Staphylococcus aureus
    Aurélie Rieu
    Laboratoire de Recherche En Vigne et Vin REVV, Universite de Bourgogne, IUVV, F 21000 Dijon, France
    Int J Food Microbiol 126:76-82. 2008
    ..monocytogenes EGD-e cells was observed in the presence of S. aureus CIP 53.156 cell-free supernatant. This activity was retained after ultrafiltation (<3 kDa), was heat stable but was lost after proteinase K treatment...
  38. pmc Molecular cloning, sequencing, and identification of a metalloprotease gene from Listeria monocytogenes that is species specific and physically linked to the listeriolysin gene
    E Domann
    Institut fur Genetik und Mikrobiologie, Universitat Wurzburg, Federal Republic of Germany
    Infect Immun 59:65-72. 1991
    ..We have designated this gene mpl for metalloprotease of L. monocytogenes. The gene was present only in pathogenic L. monocytogenes strains, in which it was physically linked to the listeriolysin gene...
  39. ncbi A single substitution in the putative helix-turn-helix motif of the pleiotropic activator PrfA attenuates Listeria monocytogenes virulence
    B Sheehan
    Unité des Interactions Bactéries Cellules, CNRS URA 1300, Institut Pasteur, Paris, France
    Mol Microbiol 20:785-97. 1996
    ..Our results strongly support the hypothesis that PrfA is a structural and functional homologue of CAP. In addition, they establish a clear correlation between DNA binding by PrfA, virulence-gene activation, and virulence...
  40. ncbi A sigma(54)-dependent PTS permease of the mannose family is responsible for sensitivity of Listeria monocytogenes to mesentericin Y105
    K Dalet
    Laboratoire de Microbiologie Fondamentale et Appliquée, CNRS ESA 6031, IBMIG, UFR Sciences, 40 Avenue du Recteur Pineau, 86022 Poitiers Cedex, France
    Microbiology 147:3263-9. 2001
    ..Taken together, the results of this work demonstrate that Ell(t)(Man) is prominent in sensitivity to mesentericin Y105 and could be a receptor for subclass IIa bacteriocins...
  41. pmc Differential inlA and inlB expression and interaction with human intestinal and liver cells by Listeria monocytogenes strains of different origins
    Hadewig Werbrouck
    Institute for Agricultural and Fisheries Research, Unit Technology and Food Product Quality and Food Safety, Brusselsesteenweg 370, 9090 Melle, Belgium
    Appl Environ Microbiol 72:3862-71. 2006
    ..monocytogenes strains. The lower capacity of clinical strains to invade HepG2 cells and to induce IL-8 is possibly a mechanism of immune evasion used by specific L. monocytogenes strains...
  42. pmc A Mutation in the luxS gene influences Listeria monocytogenes biofilm formation
    Shlomo Sela
    Microbial Food Safety Research Unit, Department of Food Sciences, Institute for Technology and Storage of Fresh Produce, Agricultural Research Organization ARO, The Volcani Center, Beth Dagan 50250, Israel
    Appl Environ Microbiol 72:5653-8. 2006
    ..Exogenous AI-2 failed to restore the wild-type phenotype to the mutant. It seems that an intact luxS gene is associated with repression of components required for attachment and biofilm formation...
  43. pmc A single-nucleotide-polymorphism-based multilocus genotyping assay for subtyping lineage I isolates of Listeria monocytogenes
    Thomas F Ducey
    Microbial Genomics and Bioprocessing Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, U S Department of Agriculture, 1815 North University Street, Peoria, IL 61604, USA
    Appl Environ Microbiol 73:133-47. 2007
    ..DNA sequences were deposited in the GenBank database under accession numbers DQ 812146 to DQ 812517, DQ 843664 to DQ 844598, and AY 512391 to AY 512502...
  44. ncbi Dimeric structure of the cell shape protein MreC and its functional implications
    Fusinita van den Ent
    MRC LMB, Hills Road, Cambridge CB2 2QH, UK
    Mol Microbiol 62:1631-42. 2006
    ..Deletion analyses indicate which domains of B. subtilis MreC are required for interaction with MreD as well as with the PBPs...
  45. ncbi Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm
    Hideki Hara
    Department of Microbiology, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Immunol 180:7859-68. 2008
    ..monocytogenes...
  46. doi The DegU orphan response regulator of Listeria monocytogenes autorepresses its own synthesis and is required for bacterial motility, virulence and biofilm formation
    Ibtissem Gueriri
    Unité de Biologie des Bactéries Pathogènes à Gram Positif, CNRS URA 2172, Institut Pasteur, 25 rue du Dr Roux, Paris Cedex 15, France
    Microbiology 154:2251-64. 2008
    ..Taken together, our results indicate that despite the lack of the DegS kinase, DegU is fully functional as an orphan response regulator, and plays a central role in controlling several crucial adaptive responses in L. monocytogenes...
  47. ncbi Expression of internalin A and biofilm formation among Listeria monocytogenes clinical isolates
    G Franciosa
    Department of Food Safety and Veterinary Public Health, Unit of Microorganisms and Food Technologies, Istituto Superiore di Sanita, Rome, Italy
    Int J Immunopathol Pharmacol 22:183-93. 2009
    ..monocytogenes strains expressing either truncated or full-length InlA. These data provide a basis for further investigation of the molecular structure and composition of L. monocytogenes biofilms...
  48. doi CD44-independent activation of the Met signaling pathway by HGF and InlB
    Laurent Dortet
    Institut Pasteur, Unité des Interactions Bactéries Cellules, 25 rue du Dr Roux, 75015 Paris, France
    Microbes Infect 12:919-27. 2010
    ..Conversely, the overexpression of CD44 or CD44v6 had no significant effect on L. monocytogenes internalization. Together our results reveal that the activation of c-Met can be largely CD44-independent...
  49. pmc Critical role for the host GTPase-activating protein ARAP2 in InlB-mediated entry of Listeria monocytogenes
    Balramakrishna Gavicherla
    Department of Molecular Biology and Microbiology, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA
    Infect Immun 78:4532-41. 2010
    ..Collectively, our findings indicate that ARAP2 promotes InlB-mediated entry of Listeria, in part, by antagonizing the host GTPase Arf6...
  50. doi A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response
    Alice Lebreton
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
    Science 331:1319-21. 2011
    ..Murine listeriosis decreased in BAHD1(+/-) mice or when lntA was constitutively expressed. Thus, the LntA-BAHD1 interplay may modulate IFN-λ-mediated immune response to control bacterial colonization of the host...
  51. ncbi Identification and characterization of an essential gene in Listeria monocytogenes using an inducible gene expression system
    Kiera M Considine
    Department of Microbiology, University College Cork, Ireland
    Bioeng Bugs 2:150-9. 2011
    ..In conclusion, this study reveals for the first time that lmo1594 is absolutely essential for listerial cell growth and survival, and also plays an important role in listerial barotolerance...
  52. doi SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe
    Qingchun Zhou
    Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Science, Central China Normal University, Luo Yu Road 152, Wuhan, People s Republic of China
    Curr Microbiol 64:234-41. 2012
    ..subtilis, rsbU in EGDeΔsigB may compensate for the σ (B)-dependent genes that are necessary for tolerance to rifampin stress and therefore plays a role in overcoming the antibiotic-triggered growth arrest...
  53. pmc Re-evaluation of the significance of penicillin binding protein 3 in the susceptibility of Listeria monocytogenes to β-lactam antibiotics
    Agata Krawczyk-Balska
    Department of Applied Microbiology, Institute of Microbiology, University of Warsaw, Miecznikowa 1, 02 096 Warsaw, Poland
    BMC Microbiol 12:57. 2012
    ..However, studies examining the effects of mutations in genes encoding known and putative L. monocytogenes PBPs have demonstrated that inactivation of lmo1438 does not affect sensitivity to β-lactams...
  54. pmc Role for telomerase in Listeria monocytogenes infection
    Ascel Samba-Louaka
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
    Infect Immun 80:4257-63. 2012
    ..Together, our data provide evidence that these bacteria trigger hTERT degradation, an event that is detrimental to bacterial replication...
  55. pmc MudPIT profiling reveals a link between anaerobic metabolism and the alkaline adaptive response of Listeria monocytogenes EGD-e
    Rolf E Nilsson
    Food Safety Centre, Tasmanian Institute of Agriculture, School of Agricultural Science, University of Tasmania, Hobart, Tasmania, Australia
    PLoS ONE 8:e54157. 2013
    ..This has important implications for the packaging of fresh and ready-to-eat foods under reduced oxygen conditions in environments where potential exists for alkaline adaptation...
  56. pmc Chitinase expression in Listeria monocytogenes is positively regulated by the Agr system
    Dafni Katerina Paspaliari
    Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark
    PLoS ONE 9:e95385. 2014
    ..Our results highlight a previously unrecognized role of the agr system and suggest that autoinducer-based regulation of chitinolytic systems may be more commonplace than previously thought. ..
  57. pmc Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance
    Conor Feehily
    Bacterial Stress Response Group, Microbiology, School of Natural Sciences, College of Science, National University of Ireland, Galway, Galway, Ireland
    PLoS ONE 9:e112649. 2014
    ..Furthermore, we also provide evidence that there might be a separate line of evolution in the GAD system between two commonly used reference strains. ..
  58. doi The roles of noncoding RNA Rli60 in regulating the virulence of Listeria monocytogenes
    Ye Long Peng
    College of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China
    J Microbiol Immunol Infect 49:502-8. 2016
    ..As a member of ncRNA, however, the function of Rli60 in regulating LM virulence remain unclear. The aim of this study was to investigate the role of Rli60 in regulating LM virulence...
  59. doi A naturally occurring prfA truncation in a Listeria monocytogenes field strain contributes to reduced replication and cell-to-cell spread
    Sebastian Rupp
    Division of Neurological Sciences, Department of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern CH 3001, Switzerland Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern CH 3012, Switzerland
    Vet Microbiol 179:91-101. 2015
    ..In contrast, complementation with the truncated version of prfA had no effect. Taken together, these results suggest that the truncated C-terminus of prfA considerably contributes to the strongly attenuated phenotype observed in vitro. ..
  60. pmc Aminopeptidase T of M29 Family Acts as A Novel Intracellular Virulence Factor for Listeria monocytogenes Infection
    Changyong Cheng
    College of Animal Science and Technology, Zhejiang A and F University, 88 Huanchengbei Road, Lin an, Zhejiang 311300, P R China
    Sci Rep 5:17370. 2015
    ..We conclude that Lmo1603 encodes a functional aminopeptidase T of M29 family, which acts as a novel intracellular virulence factor essential in the successful establishment of L. monocytogenes infections in a mouse model. ..
  61. pmc Identification and characterization of Di- and tripeptide transporter DtpT of Listeria monocytogenes EGD-e
    Jeroen A Wouters
    Wageningen Centre for Food Sciences WCFS and Laboratory of Food Microbiology, Wageningen University, Bomenweg 2, 6703 HD Wageningen, The Netherlands
    Appl Environ Microbiol 71:5771-8. 2005
    ..These studies reveal that DptT may contribute to the virulence of L. monocytogenes...
  62. pmc K+ efflux is required for histone H3 dephosphorylation by Listeria monocytogenes listeriolysin O and other pore-forming toxins
    Mélanie Anne Hamon
    Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris F 75015, France
    Infect Immun 79:2839-46. 2011
    ..Therefore, our study unveils K(+) efflux as an important signal leading to two independent events critical for infection, inflammasome activation and histone modification...
  63. pmc Sortase independent and dependent systems for acquisition of haem and haemoglobin in Listeria monocytogenes
    Qiaobin Xiao
    Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA
    Mol Microbiol 80:1581-97. 2011
    ..Finally, ΔhupDGC increased the LD(50) of L. monocytogenes 100-fold in the mouse infection model, reiterating the importance of this system in listerial virulence...
  64. doi Role of flhA and motA in growth of Listeria monocytogenes at low temperatures
    Mirjami Mattila
    Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    Int J Food Microbiol 148:177-83. 2011
    ..The results suggest that flhA and motA play a role in the cold tolerance of L. monocytogenes strain EGD-e, and that motile flagella may be needed for optimal cold stress response of L. monocytogenes...
  65. doi Intrahost passage alters SigB-dependent acid resistance and host cell-associated kinetics of Listeria monocytogenes
    Hiroshi Asakura
    Division of Biomedical Food Research, National Institute of Health Sciences, Kamiyoga 1 18 1, Setagaya Ku, Tokyo 158 8501, Japan
    Infect Genet Evol 12:94-101. 2012
    ..monocytogenes. Our study provides new insight into the potential role of intrahost environment in the process of bacterial evolution...
  66. doi Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes
    Georgina C Dowd
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    FEMS Microbiol Lett 327:118-25. 2012
    ..monocytogenes. Quantitative RT-PCR demonstrated significant de-repression of zurA, lmo0153, and lmo1671 in the zurR mutant background indicating that these putative transporters are ZurR regulated...
  67. doi Genes encoding putative DEAD-box RNA helicases in Listeria monocytogenes EGD-e are needed for growth and motility at 3°C
    Annukka Markkula
    Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, PO Box 66, FI 00014 University of Helsinki, Finland
    Environ Microbiol 14:2223-32. 2012
    ..This study shows that the putative DEAD-box RNA helicase genes lmo0866, lmo1450 and lmo1722 are necessary for cold tolerance and motility of L. monocytogenes EGD-e...
  68. doi Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis
    Matthew B Nodwell
    Department Chemie, Centre for Integrated Protein Science CIPSM, Institute of Advanced Studies, Technische Universitat Munchen, Lichtenbergstrasse 4, 85747, Garching, Germany
    Chembiochem 13:1439-46. 2012
    ..This represents the first example of a small-molecule inhibitor of ThiD...
  69. ncbi Cloning of a superoxide dismutase gene from Listeria ivanovii by functional complementation in Escherichia coli and characterization of the gene product
    A Haas
    Institut fur Genetik und Mikrobiologie, Universitat Wurzburg, FRG
    Mol Gen Genet 231:313-22. 1992
    ..coli and protected sodA sodB mutants against the toxic effects of paraquat. Subunits of the recombinant Listeria SOD and of both E. coli SODs formed enzymatically active hybrids in vivo...
  70. pmc Listeria monocytogenes isolates can be classified into two major types according to the sequence of the listeriolysin gene
    O F Rasmussen
    Department of Molecular Food Technology, Biotechnological Institute, Lyngby, Denmark
    Infect Immun 59:3945-51. 1991
    ..Assays based on hybridization or the polymerase chain reaction with type-specific oligonucleotides may provide fast and easy alternative methods for strain typing...
  71. ncbi Characterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene
    R Zink
    Institut fur Mikrobiologie, Technische Universitat Munchen, Freising, Germany
    Microbiology 141:2577-84. 1995
    ....
  72. ncbi Common features of gram-positive bacterial proteins involved in cell recognition
    S Dramsi
    Mol Microbiol 9:1119-21. 1993
  73. pmc The virulence gene cluster of Listeria monocytogenes is also present in Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species
    E Gouin
    Unité des Interactions Bactéries Cellules, Centre National de la Recherche Scientifique URA 1300, Institut Pasteur, Paris, France
    Infect Immun 62:3550-3. 1994
    ..This virulence gene cluster was detected exclusively in hemolytic Listeria species, Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species...
  74. pmc The ActA protein of Listeria monocytogenes acts as a nucleator inducing reorganization of the actin cytoskeleton
    S Pistor
    Gesellschaft fur Biotechnologische Forschung, Abteilung Mikrobiologie, Germany
    EMBO J 13:758-63. 1994
    ..Our results identify the ActA polypeptide as a nucleator of the actin cytoskeleton and provide the first insights into the molecular nature of such controlling elements in microfilament organization...
  75. ncbi A new PrfA-regulated gene of Listeria monocytogenes encoding a small, secreted protein which belongs to the family of internalins
    F Engelbrecht
    Theodor Boveri Institut für Biowissenschaften der Universität Würzburg, Germany
    Mol Microbiol 21:823-37. 1996
    ..An InlC deletion mutant shows reduced virulence when tested in an intravenous mouse model, but intracellular replication of the mutant in Caco-2 and J774 cells appears to be comparable with that of the wild-type strain...
  76. pmc Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in pathogenic potential
    M Wiedmann
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 65:2707-16. 1997
    ..monocytogenes subspecies. None of the 20 human isolates available but 11% of our animal isolates were grouped in this lineage, indicating that strains in this lineage might have reduced virulence for humans...
  77. ncbi Sequence comparison of the chromosomal regions encompassing the internalin C genes (inlC) of Listeria monocytogenes and L. ivanovii
    F Engelbrecht
    Theodor Boveri Institut für Biowissenschaften, Lehrstuhl fur Mikrobiologie, Universitat Wurzburg, Germany
    Mol Gen Genet 257:186-97. 1998
    ..Transcription of i-inlC and i-inlD is strictly dependent on the transcriptional activator PrfA, which regulates transcription of most of the known virulence genes (including inlC) of L. monocytogenes and of L. ivanovii...
  78. pmc Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires D-alanine for growth
    R J Thompson
    Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Immun 66:3552-61. 1998
    ..monocytogenes equivalent to that induced by the wild-type organism...
  79. ncbi Characterisation of a new operon encoding a Zur-like protein and an associated ABC zinc permease in Listeria monocytogenes
    K Dalet
    Laboratoire de Biologie Moleculaire, ESA CNRS 6031, IBMIG, UFR Sciences, Poitiers, France
    FEMS Microbiol Lett 174:111-6. 1999
    ..The expression of this operon is regulated by the zinc concentration...
  80. pmc Identification of an ATP-driven, osmoregulated glycine betaine transport system in Listeria monocytogenes
    R Ko
    Departments of Food Science and Technology, University of California, Davis, Davis, California 95616, USA
    Appl Environ Microbiol 65:4040-8. 1999
    ..That glycine betaine uptake is nearly eliminated in the mutant strain when it is assayed in the absence of Na(+) is an indication that only the ATP-dependent transporter and the Na(+)-glycine betaine symporter occur in L. monocytogenes...
  81. pmc OppA of Listeria monocytogenes, an oligopeptide-binding protein required for bacterial growth at low temperature and involved in intracellular survival
    E Borezee
    INSERM U411, Faculte de Medecine Necker, 75730 Paris Cedex 15, France
    Infect Immun 68:7069-77. 2000
    ..These results show the major role of OppA in the uptake of oligopeptides and the pleiotropic effects of this oligopeptide-binding protein on the behavior of this pathogen in the environment and in its host...
  82. ncbi Characterization by molecular cloning and sequencing of the gene encoding an aminopeptidase from Listeria monocytogenes
    D K Winters
    University, of Arkansas, Department of Food Science, Fayetteville 72701, USA
    Antonie Van Leeuwenhoek 78:141-51. 2000
    ..The organization of the locus, designated pep, is presented along with the characterization of the gene products of the pep locus...
  83. pmc Analysis of the role of OpuC, an osmolyte transport system, in salt tolerance and virulence potential of Listeria monocytogenes
    R D Sleator
    Department of Microbiology and National Food Biotechnology Centre, University College, Cork, Ireland
    Appl Environ Microbiol 67:2692-8. 2001
    ..Altering OpuC resulted in a significant reduction in the ability of Listeria to colonize the upper small intestine and cause subsequent systemic infection following peroral inoculation...
  84. pmc Cloning of rel from Listeria monocytogenes as an osmotolerance involvement gene
    Yumiko Okada
    Department of Veterinary Public Health, The National Institute of Public Health, Tokyo 108 8638, Japan
    Appl Environ Microbiol 68:1541-7. 2002
    ..Our results suggest that the appropriate intracellular concentration of (p)ppGpp is essential for full osmotolerance in L. monocytogenes and that its mechanism is different from that for the accumulation of compatible solutes...
  85. ncbi Molecular characterization of the genes encoding DNA gyrase and topoisomerase IV of Listeria monocytogenes
    Robert Lampidis
    Institute of Medical Microbiology and Hygiene, Faculty of Clinical Medicine Mannheim, University of Heidelberg, D 68167 Mannheim, Germany
    J Antimicrob Chemother 49:917-24. 2002
    ..monocytogenes. However, these heterodiploid strains were not affected in their resistance to nalidixic acid. The effects of the mutant plasmids on ciprofloxacin and sparfloxacin susceptibility were only modest...
  86. ncbi Phylogenetic, amino acid content and indel analyses of the beta subunit of DNA-dependent RNA polymerase of gram-positive and gram-negative bacteria
    Robert Morse
    Food Microbial Sciences Unit, School of Food Biosciences, University of Reading, Whiteknights, UK
    Int J Syst Evol Microbiol 52:1477-84. 2002
    ....
  87. pmc SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis
    Laurel L Lenz
    Department of Molecular and Cell Biology, University of California, 401 Barker Hall, Berkeley, CA 94720 3202, USA
    Proc Natl Acad Sci U S A 100:12432-7. 2003
    ..Thus, SecA2-dependent secretion may promote release of muramyl peptides that subvert host pattern recognition...
  88. pmc Requirement of the Listeria monocytogenes broad-range phospholipase PC-PLC during infection of human epithelial cells
    ANGELIKA GRUNDLING
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115 6092, USA
    J Bacteriol 185:6295-307. 2003
    ..We speculate that the additional requirement for PC-PLC activity is for lysis of secondary double-membrane vacuoles formed during cell-to-cell spread...
  89. ncbi Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms
    Kerry L Fillgrove
    Departments of Biochemistry and Chemistry, Vanderbilt University, Nashville, Tennessee 37232 0146, USA
    J Am Chem Soc 125:15730-1. 2003
    ..The catalytic promiscuity and low efficiency of the M. loti protein suggest that it may be an intermediate in the evolution of clinically relevant fosfomycin resistance proteins such as the FosX from Listeria monocytogenese...
  90. pmc Gp96 is a receptor for a novel Listeria monocytogenes virulence factor, Vip, a surface protein
    Didier Cabanes
    Unité des Interactions Bactéries Cellules Institut Pasteur, INSERM U604, INRA USC 2020, Paris, France
    EMBO J 24:2827-38. 2005
    ..Vip thus appears as a new virulence factor exploiting Gp96 as a receptor for cell invasion and/or signalling events that may interfere with the host immune response in the course of the infection...
  91. pmc CcpC-dependent regulation of citB and lmo0847 in Listeria monocytogenes
    Hyun Jin Kim
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
    J Bacteriol 188:179-90. 2006
    ....
  92. ncbi Virulence phenotyping and molecular characterization of a low-pathogenicity isolate of Listeria monocytogenes from cow's milk
    Ling li Jiang
    Institute of Preventive Veterinary Medicine, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Zhejiang University, Hangzhou 310029, China
    Acta Biochim Biophys Sin (Shanghai) 38:262-70. 2006
    ..Taken together, this study presents some clues as to reduced virulence to mice and chicken embryos of the isolate H4 probably as a result of deletion mutations of actA...
  93. pmc The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes
    Aimee Shen
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Pathog 2:e30. 2006
    ..These studies provide the first known example to our knowledge of a transcriptional repressor functioning as a master regulator controlling nonhierarchal expression of flagellar motility genes...
  94. ncbi The mutations Lys 114 --> Gln and Asp 126 --> Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at Low pH
    Giuliano Bellapadrona
    Dipartimento di Scienze Biochimiche A Rossi Fanelli, Universita La Sapienza, Rome, Italy
    Proteins 66:975-83. 2007
    ..In contrast, the salt-bridge between Lys 114 and Asp 126 characteristic of L. innocua Dps is most likely abolished due to protonation of Asp 126...
  95. ncbi Characterization of relA and codY mutants of Listeria monocytogenes: identification of the CodY regulon and its role in virulence
    Hayley J Bennett
    1 800 Stopford Building, Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Mol Microbiol 63:1453-67. 2007
    ..monocytogenes to post-exponential phase growth and virulence...
  96. pmc Teichoic acid glycosylation mediated by gtcA is required for phage adsorption and susceptibility of Listeria monocytogenes serotype 4b
    Ying Cheng
    North Carolina State University, Department of Food Science, Raleigh, NC 27695 7624, USA
    Appl Environ Microbiol 74:1653-5. 2008
    ..The sugar substituents on teichoic acid appeared essential for the adsorption of phages A500 (serotype 4b specific) and A511 (Listeria genus specific) to serotype 4b L. monocytogenes...
  97. pmc Listeria monocytogenes EGD-e biofilms: no mushrooms but a network of knitted chains
    Aurélie Rieu
    Laboratoire de Recherche En Vigne et Vin, Universite de Bourgogne, IUVV, F 21000 Dijon, France
    Appl Environ Microbiol 74:4491-7. 2008
    ..Finally, the in-frame deletion of agrA, which encodes a transcriptional regulator, resulted in a decrease in initial adherence without affecting the subsequent biofilm development...
  98. pmc SigmaB- and PrfA-dependent transcription of genes previously classified as putative constituents of the Listeria monocytogenes PrfA regulon
    Juliane Ollinger
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 5:281-93. 2008
    ..monocytogenes 10403S, while sigma(B) regulates a wider range of virulence and stress response genes...
  99. ncbi Structural bioinformatics study of PNP from Listeria monocytogenes
    L F S M Timmers
    Faculdade de Biociencias, Pontifícia Universidade Catílica do Rio Grande do Sul, Porto Alegre RS, Brazil
    Protein Pept Lett 15:843-9. 2008
    ..We modeled the complexes of LmPNP with ligands in order to determine the structural basis for specificity. Comparative analysis of the model of LmPNP allowed identification of structural features responsible for ligand affinities...
  100. doi lmo0038 is involved in acid and heat stress responses and specific for Listeria monocytogenes lineages I and II, and Listeria ivanovii
    Jianshun Chen
    Institute of Preventive Veterinary Medicine, Zhejiang University, Hangzhou, P R China
    Foodborne Pathog Dis 6:365-76. 2009
    ....
  101. doi The alternative sigma factor sigma(L) of L. monocytogenes promotes growth under diverse environmental stresses
    Eveline Raimann
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Foodborne Pathog Dis 6:583-91. 2009
    ..monocytogenes organisms against stress conditions associated with low storage temperatures, exposure to organic acid, and elevated NaCl salt concentrations...

Research Grants1

  1. L. MONOCYTOGENES CLONAL GROUPS: ECOLOGY AND TRANSMISSION
    Martin Wiedmann; Fiscal Year: 2004
    ..4. Determine the phenotypes of L. monocytogenes clonal groups associated with specific environments and hosts and determine the genetic basis for phenotypes associated with a preference for specific habitats...

Patents14

  1. Plants with increased tolerance and/or resistance to environmental stress and increased biomass production
    Patent Number: WO2008142034-A2; Date:2008-11-27
  2. Plants with increased yield
    Patent Number: WO2009037279-A1; Date:2009-03-26
  3. Plants with increased yield
    Patent Number: WO2009037329-A2; Date:2009-03-26
  4. Lipid metabolism proteins, combinations of lipid metabolism proteins and uses thereof
    Patent Number: WO2009077406-A1; Date:2009-06-25
  5. Process for the production of lutein
    Patent Number: EP2096177-A2; Date:2009-09-02
  6. Method for producing a transgenic plant cell, a plant or a part thereof with increased resistance biotic stress
    Patent Number: WO2010037714-A1; Date:2010-04-08
  7. Plants with increased yield (nue)
    Patent Number: WO2010046221-A1; Date:2010-04-29
  8. Process for the production of fine chemicals
    Patent Number: EP2194140-A2; Date:2010-06-09
  9. Process for the control of production of fine chemicals
    Patent Number: EP2199304-A1; Date:2010-06-23
  10. Proteins associated with abiotic stress response and homologs
    Patent Number: EP2221382-A2; Date:2010-08-25
  11. STRUCTURE-BASED COMPOUND DESIGN INVOLVING RIBOSWITCHES
    Patent Number: JP2012065661-A; Date:2012-04-05
  12. STRUCTURE-BASED COMPOUND DESIGN INVOLVING RIBOSWITCHES
    Patent Number: JP2008518630-A; Date:2008-06-05
  13. Proteins associated with abiotic stress response and homologs
    Patent Number: WO2007110314-A; Date:2007-10-04
  14. Listeria inocua, genome and applications
    Patent Number: WO0228891-A2; Date:2002-04-11