Lactococcus lactis subsp. cremoris

Summary

Alias: Plasmid pNZ4000, "Streptococcus hollandicus" Scholl 1891, "Streptococcus lactis B" Ayers et al. 1924, Lactococcus cremoris, Lactococcus lactis (SUBSP. CREMORIS), Lactococcus lactis cremoris, Lactococcus lactis subsp. cremoris (Orla-Jensen 1919) Schleifer et al. 1986, Streptococcus cremoris, Streptococcus cremoris Orla-Jensen 1919 (Approved Lists 1980), Streptococcus hollandicus, Streptococcus lactis B, Streptococcus lactis subsp. cremoris, Streptococcus lactis subsp. cremoris (Orla-Jensen 1919) Garvie and Farrow 1982, Lactobacillus cremoris

Top Publications

  1. pmc Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation
    G Buist
    Department of Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    J Bacteriol 177:1554-63. 1995
  2. ncbi Detection and characterization of a bacteriocin produced by Lactococcus lactis subsp. cremoris R isolated from radish
    Z Yildirim
    Department of Food Science and Arkansas Biotechnology Center, University of Arkansas, Fayetteville 72704, USA
    Lett Appl Microbiol 26:297-304. 1998
  3. pmc Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment
    Roland J Siezen
    Centre for Molecular andBiomolecular Informatics, Radboud University, P O Box 9010, 6500GL Nijmegen, The Netherlands
    Appl Environ Microbiol 71:8371-82. 2005
  4. doi A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcus lactis subsp. cremoris
    Etienne Dako
    Ecole des sciences des aliments, de Nutrition et d Etudes Familiales, Faculté des sciences de la santé et des services communautaires, Université de Moncton N B Canada, E1A 3E9
    Int J Food Microbiol 126:186-94. 2008
  5. pmc Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains
    J R Reid
    Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 60:801-6. 1994
  6. pmc Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363
    Udo Wegmann
    Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    J Bacteriol 189:3256-70. 2007
  7. pmc Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris: isolation and characterization of the protein and its gene
    H Holo
    Laboratory of Microbial Gene Technology, Oslo, Norway
    J Bacteriol 173:3879-87. 1991
  8. pmc Duplication of the pepF gene and shuffling of DNA fragments on the lactose plasmid of Lactococcus lactis
    M Nardi
    Unité de Recherches de Biochimie et Structure des Protéines, INRA, Jouy en Josas, France
    J Bacteriol 179:4164-71. 1997
  9. pmc Characterization and role of the branched-chain aminotransferase (BcaT) isolated from Lactococcus lactis subsp. cremoris NCDO 763
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, 78352 Jouy en Josas, France
    Appl Environ Microbiol 66:571-7. 2000
  10. ncbi [Influence of expression of transglutaminase on the growth of Lactococcus lactis]
    Rui Yan Fu
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, China
    Wei Sheng Wu Xue Bao 45:510-5. 2005

Patents

  1. CONTROLLED GROWTH OF MICROORGANISMS
  2. Production of consumable products
  3. Production of stilbenoids
  4. Method for preparing proteins using transformed lactic acid bacteria
  5. DNA fragments, containing a lactic acid bacterium-specific regulator region for the expression of genes coding for normally heterologous proteins
  6. Marker genes for genetic manipulation
  7. A method of improving the production of biomass or a desired product from a cell
  8. Methods for the screening of antibacterial substances
  9. Fermented milk having expression inducing effect of interferon gamma and inoculum for producing fermented milk

Scientific Experts

Detail Information

Publications155 found, 100 shown here

  1. pmc Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation
    G Buist
    Department of Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    J Bacteriol 177:1554-63. 1995
    ..By replacement recombination, an acmA deletion mutant which grew as long chains was constructed, indicating that AcmA is required for cell separation...
  2. ncbi Detection and characterization of a bacteriocin produced by Lactococcus lactis subsp. cremoris R isolated from radish
    Z Yildirim
    Department of Food Science and Arkansas Biotechnology Center, University of Arkansas, Fayetteville 72704, USA
    Lett Appl Microbiol 26:297-304. 1998
    ..Lactococcin R differs from nisin in having a lower molecular weight, 2.5 kDa vs 3.4 kDa, and in being sensitive to pepsin and alpha-chymotrypsin to which nisin is resistant...
  3. pmc Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment
    Roland J Siezen
    Centre for Molecular andBiomolecular Informatics, Radboud University, P O Box 9010, 6500GL Nijmegen, The Netherlands
    Appl Environ Microbiol 71:8371-82. 2005
    ..A substantial number of these "adaptation" genes have not been described before on L. lactis plasmids. Moreover, several genes were identified for the first time in L. lactis, possibly reflecting horizontal gene transfer...
  4. doi A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcus lactis subsp. cremoris
    Etienne Dako
    Ecole des sciences des aliments, de Nutrition et d Etudes Familiales, Faculté des sciences de la santé et des services communautaires, Université de Moncton N B Canada, E1A 3E9
    Int J Food Microbiol 126:186-94. 2008
    ..Analysis by denaturing polyacrylamide gel electrophoresis with Mc5 cell walls incorporated as the autolysin's substrate identified a band corresponding to PA49.5 in the second peak of protein secretion...
  5. pmc Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains
    J R Reid
    Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 60:801-6. 1994
    ..abstract truncated at 250 words)..
  6. pmc Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363
    Udo Wegmann
    Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    J Bacteriol 189:3256-70. 2007
    ..The availability of the L. lactis MG1363 genome sequence will reinforce its status as the prototype among lactic acid bacteria through facilitation of further applied and fundamental research...
  7. pmc Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris: isolation and characterization of the protein and its gene
    H Holo
    Laboratory of Microbial Gene Technology, Oslo, Norway
    J Bacteriol 173:3879-87. 1991
    ..The other lactococcal strains transformed with the same recombinant plasmid became resistant to LCN-A but did not produce any detectable amount of the bacteriocin...
  8. pmc Duplication of the pepF gene and shuffling of DNA fragments on the lactose plasmid of Lactococcus lactis
    M Nardi
    Unité de Recherches de Biochimie et Structure des Protéines, INRA, Jouy en Josas, France
    J Bacteriol 179:4164-71. 1997
    ..This suggests that the duplication of pepF occurred by recombination from the chromosome of an L. lactis subsp. lactis strain followed by gene transfer. We discuss the possible functions of PepF and the role of its amplification...
  9. pmc Characterization and role of the branched-chain aminotransferase (BcaT) isolated from Lactococcus lactis subsp. cremoris NCDO 763
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, 78352 Jouy en Josas, France
    Appl Environ Microbiol 66:571-7. 2000
    ..Since this enzyme is still active under cheese-ripening conditions, it certainly plays a major role in cheese flavor development...
  10. ncbi [Influence of expression of transglutaminase on the growth of Lactococcus lactis]
    Rui Yan Fu
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, China
    Wei Sheng Wu Xue Bao 45:510-5. 2005
    ....
  11. doi Genotypic and technological characterization of Lactococcus lactis isolates involved in processing of artisanal Manchego cheese
    P Nieto-Arribas
    Departamento de Química Analítica y Tecnología de Alimentos, Facultad de Quimicas, Universidad de Castilla La Mancha, Ciudad Real, Spain
    J Appl Microbiol 107:1505-17. 2009
    ..Genotypic and technological characterization of wild lactococci isolated from artisanal Manchego cheese during the ripening process for selection of suitable starter cultures...
  12. pmc Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages
    Azra Yasmin
    School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
    J Bacteriol 192:1122-30. 2010
    ..The eight phages were tested for their ability to package host DNA, and three were shown to be very effective for generalized transduction of naive host cells of the laboratory strains OG1RF and JH2-2...
  13. ncbi Molecular characterization of the restriction endonuclease gene (scrFIR) associated with the ScrFI restriction/modification system from Lactococcus lactis subsp. cremoris UC503
    D P Twomey
    Department of Microbiology, University College, Cork, Ireland
    Microbiology 143:2277-86. 1997
    ..The ability of ScrFI to cleave non-canonically modified 5' CCNGG 3' sequences suggested that some ScrFI sites may require complex modifications to fully impair digestion by this enzyme...
  14. ncbi Effect of liquid feeding weaned pigs on growth performance to harvest
    P G Lawlor
    Pig Production Department, Teagasc, Moorepark Research Centre, Fermoy Co, Cork, Ireland
    J Anim Sci 80:1725-35. 2002
    ..No benefit arose from feeding fresh liquid feed or fermented liquid feed. Growth performance from d 28 after weaning to harvest was not improved by any liquid feed treatment...
  15. pmc The riboflavin transporter RibU in Lactococcus lactis: molecular characterization of gene expression and the transport mechanism
    Catherine M Burgess
    Alimentary Pharmabiotic Centre, Department of Microbiology and Biosciences Institute, National University of Ireland Cork, Western Road, Cork, Ireland
    J Bacteriol 188:2752-60. 2006
    ..The presented transport data are consistent with a uniport mechanism for riboflavin translocation and provide the first detailed molecular and functional analysis of a bacterial protein involved in riboflavin transport...
  16. pmc Genetic organization and molecular analysis of the EcoVIII restriction-modification system of Escherichia coli E1585-68 and its comparison with isospecific homologs
    Iwona Mruk
    Department of Microbiology, University of Gdansk, Kladki 24, 80 822 Gdansk, Poland
    Appl Environ Microbiol 69:2638-50. 2003
    ..LlaCI but not with M. HindIII. R. EcoVIII requires Mg(II) ions for phosphodiester bond cleavage. We found that the same ions are strong inhibitors of the M. EcoVIII enzyme. The biological implications of this finding are discussed...
  17. ncbi Effectiveness and stability of plastic films coated with nisin for inhibition of Listeria monocytogenes
    Hudaa Neetoo
    Department of Animal and Food Sciences, University of Delaware, Newark, Delaware 19716 2150, USA
    J Food Prot 70:1267-71. 2007
    ..The results of this study demonstrate that commercially available packaging films can be coated with nisin and the resulting antimicrobial films can be conveniently stored at room temperature with no adverse effect on nisin activity...
  18. doi Production of fresh Cheddar cheese curds with controlled postacidification and enhanced flavor
    D St-Gelais
    Food Research and Development Centre, Agriculture and Agri Food Canada, 3600 Casavant Blvd West, Saint Hyacinthe, Quebec, Canada J2S 8E3
    J Dairy Sci 92:1856-63. 2009
    ..cheese manufacturing, streptococci became the dominant microflora in all cheeses, whereas populations of Lactococcus cremoris and L. diacetylactis decreased. During cheese storage, viable counts of L...
  19. ncbi Feasibility studies to control acute diarrhoea in children by feeding fermented milk preparations Actimel and Indian Dahi
    K N Agarwal
    Department of Paediatrics, University College of Medical Sciences and GTB Hospital, Delhi, India
    Eur J Clin Nutr 56:S56-9. 2002
    ..Group 2 was given Indian Dahi (Lf 40) containing 10(8) of each Lactococcus lactis, Lactococcus lactis cremoris and Leuconostac mesenteroides cremoris per gram...
  20. pmc Identification and characterization of lactococcal-prophage-carried superinfection exclusion genes
    Jennifer Mahony
    Department of Microbiology, University College Cork, Western Road, Cork, Ireland
    Appl Environ Microbiol 74:6206-15. 2008
    ..Sie-specifying genes found on the MG1363 prophages are also present in various lactococcal strains, whereas the prophage-encoded Sie systems of IL1403 do not appear to be as widely disseminated...
  21. pmc An aminotransferase from Lactococcus lactis initiates conversion of amino acids to cheese flavor compounds
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, Jouy en Josas, France
    Appl Environ Microbiol 63:414-9. 1997
    ..5 kDa. The activity of the enzyme is optimal between pH 6.5 and 8 and between 35 and 45 degrees C, but it is still active under cheese-ripening conditions...
  22. pmc Characterization of a thiol-dependent endopeptidase from Lactobacillus helveticus CNRZ32
    K M Fenster
    Department of Food Science, University of Wisconsin Madison 53706, USA
    J Bacteriol 179:2529-33. 1997
    ..1). PepE hydrolyzed internal peptide bonds in Met-enkephalin and bradykinin; however, hydrolysis of alpha-, beta-, and kappa-caseins was not detected...
  23. ncbi Sequencing of variable regions of the 16S rRNA gene for identification of lactic acid bacteria isolated from the intestinal microbiota of healthy salmonids
    José Luis Balcázar
    Laboratory of Fish Pathology, Faculty of Veterinary Sciences, University of Zaragoza, Zaragoza 50013, Spain
    Comp Immunol Microbiol Infect Dis 30:111-8. 2007
    ..cremoris, Lactococcus lactis subsp. lactis, and Leuconostoc mesenteroides. The method described was found to be a very simple, rapid, specific, and low-cost tool for the identification of unknown strains of LAB...
  24. ncbi [Comparison of the homologous SfeI and LlaBI restriction-modification systems]
    S S Okhapkina
    Institute of Molecular Biology, Vektor State Research Center of Virology and Biotechnology, Kol tsovo, Novosibirsk Region, 633159 Russia
    Mol Biol (Mosk) 36:432-7. 2002
    ..No homology was observed between operon-flanking sequences of the two closely related species, suggesting horizontal transfer of the operon...
  25. ncbi Cloning, sequencing and comparison of three lactococcal L-lactate dehydrogenase genes
    S R Swindell
    AFRC Institute of Food Research, Norwich Laboratory, Colney, UK
    Microbiology 140:1301-5. 1994
    ..9% homologous. Our results provide further evidence that L. lactis subsp. Lactis MG1363 and other L. lactis subsp. Lactis NCDO 712 derived strains should be reclassified as Lactococcus lactis subsp. cremoris...
  26. pmc Cloning, sequencing, and expression of the pyruvate carboxylase gene in Lactococcus lactis subsp. lactis C2
    H Wang
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota 55108, USA
    Appl Environ Microbiol 66:1223-7. 2000
    ..lactis KB4. The deduced lactococcal Pyc protein was highly homologous to Pyc sequences of other bacteria. The pyc gene was also detected in Lactococcus lactis subsp. cremoris and L. lactis subsp. lactis bv. diacetylactis strains...
  27. pmc Cloning and sequencing of LlaDCHI [corrected] restriction/modification genes from Lactococcus lactis and relatedness of this system to the Streptococcus pneumoniae DpnII system
    S Moineau
    Quest International, Sarasota, Florida 34243, USA
    Appl Environ Microbiol 61:2193-202. 1995
    ..The deduced amino acid sequence of M.LlaIIA was 75% identical with that of M.DpnII, whereas M.LlaIIB was 88% identical with M.DpnA. However, R.LlalII shared only 31% identity with R.DpnII...
  28. pmc A maturation protein is essential for production of active forms of Lactococcus lactis SK11 serine proteinase located in or secreted from the cell envelope
    P Vos
    Department of Biophysical Chemistry, Netherlands Institute for Dairy Research, Ede
    J Bacteriol 171:2795-802. 1989
    ..Expression studies of L. lactis clones containing these plasmids showed that the prtM gene encodes a trans-acting activity involved in the maturation of cell envelope-located and -secreted forms of the SK11 proteinase...
  29. ncbi Primary structure and organization of the gene for a procaryotic, cell envelope-located serine proteinase
    P Vos
    Department of Biophysical Chemistry, Netherlands Institute for Dairy Research NIZO, Ede
    J Biol Chem 264:13579-85. 1989
    ..Furthermore, a region was identified in the Lactococcus proteinase, which shows homology to the membrane-anchoring domains of a number of proteins from other Gram-positive bacteria...
  30. pmc Identification of a new insertion element, similar to gram-negative IS26, on the lactose plasmid of Streptococcus lactis ML3
    K M Polzin
    Central Institute for Microbiological Research, Tokyo, Japan
    J Bacteriol 169:5481-8. 1987
    ..5% identical) of the open reading of frame...
  31. ncbi Microencapsulation of Lactococcus lactis subsp. cremoris
    B C Larisch
    Department of Chemical Engineering, McGill University, , , Canada
    J Microencapsul 11:189-95. 1994
    ..The rate of lactic acid production was approximately 2 mmol/h at an encapsulated cell concentration of 4 x 10(8) cfu/ml...
  32. pmc Cloning and sequencing of pepC, a cysteine aminopeptidase gene from Lactococcus lactis subsp. cremoris AM2
    M P Chapot-Chartier
    Station de Recherches Laitières, Institut National de la Recherche Agronomique, Jouy en Josas, France
    Appl Environ Microbiol 59:330-3. 1993
    ..A portion of the predicted amino acid sequence of PepC (436 amino acids) showed strong homology to the active site of cysteine proteases. No signal sequence was found, indicating an intracellular location of the enzyme...
  33. pmc Characterization of genetic elements required for site-specific integration of the temperate lactococcal bacteriophage phi LC3 and construction of integration-negative phi LC3 mutants
    D Lillehaug
    Laboratory of Microbial Gene Technology, Norwegian Research Council, As
    J Bacteriol 175:1745-55. 1993
    ..Phage phi LC3 int- and int-attP-defective mutants, conferring an abortive lysogenic phenotype, were constructed...
  34. ncbi Analysis of heat shock gene expression in Lactococcus lactis MG1363
    J Arnau
    Department of Dairy and Food Science, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Microbiology 142:1685-91. 1996
    ..lactis MG1363 is presented. A gene located downstream of the dnaK operon in strain MG1363, named orf4, was shown not to be regulated by heat shock...
  35. ncbi Replication regions of two pairs of incompatible lactococcal theta-replicating plasmids
    A Gravesen
    Department of Dairy and Food Science, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    Plasmid 38:115-27. 1997
    ....
  36. pmc Characterization of multiple regions involved in replication and mobilization of plasmid pNZ4000 coding for exopolysaccharide production in Lactococcus lactis
    R van Kranenburg
    Microbial Ingredients Section, NIZO Food Research, Ede, The Netherlands
    J Bacteriol 180:5285-90. 1998
    We characterized the regions involved in replication and mobilization of the 40-kb plasmid pNZ4000, encoding exopolysaccharide (EPS) production in Lactococcus lactis NIZO B40...
  37. pmc Genetic characterization of the major lactococcal aromatic aminotransferase and its involvement in conversion of amino acids to aroma compounds
    L Rijnen
    Unité de Recherches de Biochimie et Structure des Protéines, INRA, 78352 Jouy en Josas Cedex, France
    Appl Environ Microbiol 65:4873-80. 1999
    ..However, another biosynthesis aromatic aminotransferase is induced in the absence of phenylalanine in the culture medium...
  38. ncbi The pyrH gene of Lactococcus lactis subsp. cremoris encoding UMP kinase is transcribed as part of an operon including the frr1 gene encoding ribosomal recycling factor 1
    S L Wadskov-Hansen
    Department of Microbiology, Building 301, Technical University of Denmark, DK 2800, Lyngby, Denmark
    Gene 241:157-66. 2000
    ..lactis shows a high resemblance to that found in Bacillus subtilis as well as in Escherichia coli and several other prokaryotes..
  39. pmc Inactivation of the glutamate decarboxylase gene in Lactococcus lactis subsp. cremoris
    M Nomura
    Department of Animal Products, National Institute of Animal Industry, Norindanchi, Tsukuba, Ibaraki 305 0901, Japan
    Appl Environ Microbiol 66:2235-7. 2000
    ..lactis subsp. cremoris genome but was poorly expressed. Sequence analysis showed that the gene is inactivated by the frameshift mutation and encoded in a nonfunctional protein...
  40. pmc Evidence for horizontal transfer of SsuDAT1I restriction-modification genes to the Streptococcus suis genome
    T Sekizaki
    National Institute of Animal Health, Tsukuba, Ibaraki 305 0856, Japan
    J Bacteriol 183:500-11. 2001
    ..These results suggest that the SsuDAT1I system could have been integrated into the S. suis chromosome by an illegitimate recombination mechanism...
  41. ncbi Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase
    S L Wadskov-Hansen
    Department of Microbiology, Technical University of Denmark, Building 301, DK 2800 Lyngby, Denmark
    J Biol Chem 276:38002-9. 2001
    ..As for other CTP synthases, the oligomeric structure of the lactococcal enzyme was found to be a tetramer, but unlike most of the other previously characterized enzymes, the tetramer was very stable even at dilute enzyme concentrations...
  42. pmc Cloning and expression of an oligopeptidase, PepO, with novel specificity from Lactobacillus rhamnosus HN001 (DR20)
    Camilla Christensson
    Institute of Molecular Biosciences, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 68:254-62. 2002
    ..The purified PepO enzyme demonstrated unique cleavage specificity for alpha(s1)-casein fragment 1-23, hydrolyzing the bonds Pro-5-Ile-6, Lys-7-His-8, His-8-Gln-9, and Gln-9-Gly-10. The impact of this enzyme in cheese can now be assessed...
  43. ncbi An X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis: cloning, expression in Escherichia coli, and application for removal of N-terminal Pro-Pro from recombinant proteins
    Ming Xin
    Biopharmaceutical College, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, People s Republic of China
    Protein Expr Purif 24:530-8. 2002
    ....
  44. pmc Effects of high pressure on the viability, morphology, lysis, and cell wall hydrolase activity of Lactococcus lactis subsp. cremoris
    A S Malone
    Department of Food Science and Technology, Ohio State University, Columbus, Ohio 43210, USA
    Appl Environ Microbiol 68:4357-63. 2002
    ..These data suggest that high pressure can cause inactivation, physical damage, and lysis in L. lactis. Pressure-induced lysis is strain dependent and not solely dependent upon cell wall hydrolase activity...
  45. pmc Characterization, expression, and mutation of the Lactococcus lactis galPMKTE genes, involved in galactose utilization via the Leloir pathway
    Benoît P Grossiord
    NIZO Food Research, 6710 BA Ede Laboratory of Microbiology, Wageningen University, 6703 CT Wageningen, The Netherlands
    J Bacteriol 185:870-8. 2003
    ..Recovery of the wild-type phenotype for the galE mutant was obtained either by genetic complementation or by addition of galactose to the growth medium...
  46. ncbi [The resistance conferred by the R/M system LlaBIII against bacteriophages]
    Jian Kong
    State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China
    Wei Sheng Wu Xue Bao 42:246-50. 2002
    ..The results indicated that the R/M system LlaBIII could protect strains from bacteriophages in dairy fermentation...
  47. ncbi Molecular organization of exopolysaccharide (EPS) encoding genes on the lactococcal bacteriophage adsorption blocking plasmid, pCI658
    Amanda Forde
    Department of Microbiology, University College, Cork, Ireland
    Plasmid 49:130-42. 2003
    ..Evidence of a gene encoding UDP-glucose dehydrogenase is also presented and this is the first description of such a gene in Lactococcus...
  48. ncbi Identification of operator sites of the CI repressor of phage TP901-1: evolutionary link to other phages
    Annette H Johansen
    Section of Molecular Microbiology, BioCentrum DTU, Technical University of Denmark, DK 2800, Lyngby, Denmark
    Virology 311:144-56. 2003
    ..Interestingly, the locations of these repeats on the phage genomes correspond to those found in TP901-1, indicating that the same system of cooperative repression of early phage promoters has been inherited by modular evolution...
  49. pmc Heterologous expression of lactose- and galactose-utilizing pathways from lactic acid bacteria in Corynebacterium glutamicum for production of lysine in whey
    Eoin Barrett
    Dairy Products Research Centre, Teagasc, Moorepark, Fermoy, Ireland
    Appl Environ Microbiol 70:2861-6. 2004
    ..glutamicum 21253. Despite their increased catabolic flexibility, however, the modified corynebacteria exhibited slower growth rates and plasmid instability...
  50. ncbi Deep neck infection due to Lactococcus lactis cremoris: a case report
    M Koyuncu
    Department of Otorhinolaryngology, Ondokuz Mayis University Medical School Kurupelit Campus, Samsun, Turkey
    Eur Arch Otorhinolaryngol 262:719-21. 2005
    ..cremoris. The case is associated with the consumption of unpasteurized milk and occurred in a patient with a buccal mucosa tumor. Anti-infective therapy with ceftriaxone and metronidazole resulted in complete resolution...
  51. pmc Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris Wg2
    P S Tan
    Department of Microbiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    Appl Environ Microbiol 56:526-32. 1990
    ..Kinetic studies indicated that the enzyme has a relatively low affinity for lysyl-p-nitroanilide (K(m), 0.55 mM) but that it can hydrolyze this substrate at a high rate (V(max), 30 mumol/min per mg of protein)...
  52. pmc Improved enumeration of lactic acid bacteria in mesophilic dairy starter cultures by using multiplex quantitative real-time PCR and flow cytometry-fluorescence in situ hybridization
    Udo Friedrich
    Danisco Deutschland GmbH, Busch Johannsen Str 1, D 25899 Niebüll, Germany
    Appl Environ Microbiol 72:4163-71. 2006
    ..lactis subsp. cremoris. Quantitative real-time PCR and FLOW-FISH were found to be effective and accurate tools for the bacterial community analysis of complex starter cultures...
  53. pmc Exopolysaccharide expression in Lactococcus lactis subsp. cremoris Ropy352: evidence for novel gene organization
    Eric P Knoshaug
    Department of Microbiology, Nash Hall 220, Oregon State University, Corvallis, OR 97331 3804, USA
    Appl Environ Microbiol 73:897-905. 2007
    ....
  54. ncbi Molecular cloning of porcine RP105/MD-1 involved in recognition of extracellular phosphopolysaccharides from Lactococcus lactis ssp. cremoris
    Masanori Tohno
    Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Aobaku, Sendai 981 8555, Japan
    Mol Immunol 44:2566-77. 2007
    ..These effects were mediated by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase. Thus, we identified extracellular polysaccharide from Lc.cremoris as an active substance that can induce immune activation via RP105 and MD-1...
  55. pmc AbiV, a novel antiphage abortive infection mechanism on the chromosome of Lactococcus lactis subsp. cremoris MG1363
    Jakob Haaber
    Center for Systems Microbiology, DTU BioSys, Technical University of Denmark, Lyngby, Denmark
    Appl Environ Microbiol 74:6528-37. 2008
    ..The mode of action of AbiV is unknown, but the activity of AbiV prevented cleavage of the replicated phage DNA of 936-like phages...
  56. doi The effect of ripening and storage conditions on the distribution of tyramine, putrescine and cadaverine in Edam-cheese
    Leona Buňková
    Department of Fats, Tensides and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlin, nam T G Masaryka 275, 76319 Zlín, Czech Republic
    Food Microbiol 27:880-8. 2010
    ..In starter bacteria Lactococcus lactis subsp. lactis and Lactococcus lactis subsp. cremoris the decarboxylase activity tested was not detected...
  57. doi Identification and characterization of lactic acid bacteria isolated from mixed pasture of timothy and orchardgrass, and its badly preserved silage
    Masanori Tohno
    National Agriculture and Food Research Organization, National Institute of Livestock and Grassland Science, Nasushiobara, Tochigi, Japan
    Anim Sci J 83:318-30. 2012
    ..These results are useful in understanding the diversity of LAB associated with decayed silage of timothy and orchardgrass...
  58. doi Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18
    Akemi Kosaka
    Biomedial Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305 8566, Japan
    Int Immunopharmacol 14:729-33. 2012
    ..These findings suggest that this LAB strain is an efficient activator of protective cellular immunity via stimulation of myeloid cells including DCs...
  59. pmc Lactococcus lactis cremoris infection: not rare anymore?
    Simone Hadjisymeou
    Department of ENT, Luton and Dunstable NHS Trust, London, UK
    BMJ Case Rep 2013:. 2013
    ..The ensuing histological examination revealed that the mass was caused by Lactococcus lactis cremoris. As such, the patient was treated with antibiotics and made a complete recovery...
  60. doi Proteomics analysis of the Flp regulon in Lactococcus lactis subsp. cremoris
    Ismail Akyol
    Department of Agricultural Biotechnology, Faculty of Agriculture, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey
    Electrophoresis 34:2218-28. 2013
    ..These groups are oxidative stress, electron transfer, sugars, cell wall, ABC transporters, arginine metabolism, and pyrimidine biosynthesis pathway. ..
  61. pmc Subdural empyema due to Lactococcus lactis cremoris: case report
    Mizuho Inoue
    Department of Neurosurgery, Aomori Prefectural Central Hospital
    Neurol Med Chir (Tokyo) 54:341-7. 2014
    b>Lactococcus lactis cremoris (L. lactis cremoris) infections are very rare in humans. Only three case reports of brain abscess have been reported and the infectious routes and pathological features are still unknown...
  62. doi Characterization of plant-derived lactococci on the basis of their volatile compounds profile when grown in milk
    Debebe Alemayehu
    Teagasc Food Research Centre, Moorepark, Cork, Ireland Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Int J Food Microbiol 172:57-61. 2014
    ..As such the production of a larger number of volatile compounds is a distinguishing feature of plant-derived lactococci and might be a desirable trait for the production of dairy products with enhanced flavour and/or aroma. ..
  63. doi In vivo application and dynamics of lactic acid bacteria for the four-season production of Vastedda-like cheese
    Raimondo Gaglio
    Department of Agricultural and Forest Science, Universita di Palermo, Viale delle Scienze 4, 90128 Palermo, Italy
    Int J Food Microbiol 177:37-48. 2014
    ....
  64. doi Transcription profiling of interactions between Lactococcus lactis subsp. cremoris SK11 and Lactobacillus paracasei ATCC 334 during Cheddar cheese simulation
    Emilie Desfossés-Foucault
    Institut sur la nutrition et les aliments fonctionnels INAF, Département des sciences des aliments et de nutrition, Universite Laval, G1V 0A6 QC, Canada
    Int J Food Microbiol 178:76-86. 2014
    ..These results show how complementary functions of starter and NSLAB contribute to activities useful for flavor development. ..
  65. doi Addition to thermized milk of Lactococcus lactis subsp. cremoris M104, a wild, novel nisin a-producing strain, replaces the natural antilisterial activity of the autochthonous raw milk microbiota reduced by thermization
    Alexandra Lianou
    Dairy Research Institute, Hellenic Agricultural Organization Demeter, Directorate General of Agricultural Research formerly NAGREF, Katsikas, Ioannina 45221, Greece Department of Food Science and Human Nutrition, Laboratory of Food Microbiology and Biotechnology, Agricultural University of Athens, Athens 11855, Greece
    J Food Prot 77:1289-97. 2014
    ..Thus, postthermal supplementation of thermized bulk milk with bioprotective L. lactis subsp. cremoris cultures replaces the natural antilisterial activity of raw milk reduced by thermization. ..
  66. pmc Early adaptation to oxygen is key to the industrially important traits of Lactococcus lactis ssp. cremoris during milk fermentation
    Marina Cretenet
    Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
    BMC Genomics 15:1054. 2014
    ..For those purposes, conditions of hyper-oxygenation were initially fixed for the fermentation...
  67. pmc Genome Sequence of Lactococcus lactis subsp. cremoris Mast36, a Strain Isolated from Bovine Mastitis
    Carme Plumed-Ferrer
    Food Biotechnology, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Genome Announc 3:. 2015
    ..cremoris Mast36, isolated from bovine mastitis, is reported here. This strain was shown to be able to grow in milk and still possess genes of vegetable origin. The genome also contains a cluster of genes associated with pathogenicity. ..
  68. doi Cyclopropane fatty acid synthase from Oenococcus oeni: expression in Lactococcus lactis subsp. cremoris and biochemical characterization
    Thi Mai Huong To
    Unité Mixte de Recherche Procédés Alimentaires et Microbiologiques UMR A 02 102 AgroSup Dijon Université de Bourgogne, Equipe Vin Aliment Microbiologie et Stress, Institut Universitaire de la Vigne et du Vin Jules Guyot, Rue Claude Ladrey, Campus Universitaire Montmuzard, BP 27877, 21078, Dijon, France
    Arch Microbiol 197:1063-74. 2015
    ..oeni enzyme. The current study reveals an essential hypothesis about the specificity of O. oeni CFA synthase which could play a key function in the acid tolerance mechanisms of this enological bacterium...
  69. doi Biogenic amine production by Lactococcus lactis subsp. cremoris strains in the model system of Dutch-type cheese
    Radka Flasarová
    Department of Food Technology, Faculty of Technology, Tomas Bata University in Zlin, nam T G Masaryka 5555, 760 05 Zlin, Czech Republic
    Food Chem 194:68-75. 2016
    ..In the cheeses with the addition of the strain of CCDM 946 it even exceeded 500mg/kg. In the control samples, the amount of biogenic amines was insignificant...
  70. pmc Microbial Activation of Wooden Vats Used for Traditional Cheese Production and Evolution of Neoformed Biofilms
    Raimondo Gaglio
    Dipartimento Scienze Agrarie e Forestali, Universita degli Studi di Palermo, Palermo, Italy
    Appl Environ Microbiol 82:585-95. 2015
    ..Thus, neoformed biofilms enable a reduction of microbial variability and stabilize the sensorial attributes of Vastedda cheese...
  71. doi Correction: Microencapsulation of probiotics in hydrogel particles: enhancing Lactococcus lactis subsp. cremoris LM0230 viability using calcium alginate beads
    Timothy W Yeung
    Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA
    Food Funct 7:2909. 2016
    ..Correction for 'Microencapsulation of probiotics in hydrogel particles: enhancing Lactococcus lactis subsp. cremoris LM0230 viability using calcium alginate beads' by Timothy W. Yeung et al., Food Funct., 2016, 7, 1797-1804. ..
  72. doi Putrescine biosynthesis in Lactococcus lactis is transcriptionally activated at acidic pH and counteracts acidification of the cytosol
    Beatriz del Rio
    Instituto de Productos Lacteos de Asturias, IPLA CSIC, Paseo Río Linares s n, 33300 Villaviciosa, Spain Electronic address
    Int J Food Microbiol 236:83-9. 2016
    ..Finally, the following of the AGDI pathway counteracted the acidification of the cytoplasm under acidic external conditions, suggesting it to provide protection against acid stress. ..
  73. pmc Adhesion of the genome-sequenced Lactococcus lactis subsp. cremoris IBB477 strain is mediated by specific molecular determinants
    Joanna Maria Radziwill-Bienkowska
    Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A, 02 106, Warsaw, Poland
    Appl Microbiol Biotechnol 100:9605-9617. 2016
    ..lactis strain exhibiting adhesive and mucoadhesive properties to be sequenced and demonstrated that one of the proteins containing adhesion domains contributes to adhesion...
  74. pmc Phage TP901-1 site-specific integrase functions in human cells
    Stephanie M Stoll
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305 5120, USA
    J Bacteriol 184:3657-63. 2002
    ..The TP901-1 phage integrase thus represents a new reagent for manipulating DNA in living mammalian cells...
  75. ncbi Proteome analysis of the purine stimulon from Lactococcus lactis
    Natascha H Beyer
    Protein Research Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    Proteomics 3:786-97. 2003
    ..A success rate of 68% indicates that it may be feasible to perform proteomics based upon genomic sequences of relatives outside the genus...
  76. ncbi Characterization of the LlaCI methyltransferase from Lactococcus lactis subsp. cremoris W15 provides new insights into the biology of type II restriction-modification systems
    Iwona Mruk
    Department of Microbiology, University of Gdansk, Kładki 24, 80 822 Gdansk, Poland
    Microbiology 149:3331-41. 2003
    ..This observation suggests that sensitivity of the M.LlaCI to Mg(2+) may strengthen the restriction activity of the cognate endonuclease in the bacterial cell. Other biological implications of this finding are also discussed...
  77. ncbi Peritonitis due to Lactococcus cremoris in an automated peritoneal dialysis patient
    Olivier Mat
    Nephrol Dial Transplant 18:2690-1. 2003
  78. ncbi Phenotypic and genetic diversity of Lactococcus lactis and Enterococcus spp. strains isolated from Northern Spain starter-free farmhouse cheeses
    Susana Delgado
    Instituto de Productos Lácteos de Asturias CSIC, Carretera de Infiesto s n, 33300, Asturias, Villaviciosa, Spain
    Int J Food Microbiol 90:309-19. 2004
    ..Two simple, rapid and cheap techniques (partial ARDRA and SDS-PAGE) are proposed as reliable tools for the classification and typing of new lactococcal-like isolates...
  79. ncbi Resin straw as an alternative system to securely store frozen microorganisms
    Bouachanh Thammavongs
    Laboratoire de Microbiologie Alimentaire EA3213 USC INRA, Universite de Caen Basse Normandie, 14032 Caen cedex 05, France
    J Microbiol Methods 57:181-6. 2004
    ....
  80. ncbi Characterization of mesentericin ST99, a bacteriocin produced by Leuconostoc mesenteroides subsp. dextranicum ST99 isolated from boza
    Svetoslav D Todorov
    Department of Microbiology, University of Stellenbosch, 7600, Stellenbosch, South Africa
    J Ind Microbiol Biotechnol 31:323-9. 2004
    ..Precipitation with ammonium sulfate (70% saturation), followed by Sep-Pack C18 chromatography and reverse-phase HPLC on a C18 Nucleosil column yielded one antimicrobial peptide...
  81. ncbi Phenotypic identification and technological properties of lactic acid bacteria isolated from traditionally processed fish products of the Eastern Himalayas
    Namrata Thapa
    Department of Zoology, Sikkim Government College, Gangtok 737102, Sikkim, India
    Int J Food Microbiol 107:33-8. 2006
    ..None of the strains produced biogenic amines in the method applied. This paper is the first report on the microbial composition, mostly lactic acid bacteria, of traditionally processed fish products of Eastern Himalayas...
  82. pmc Two 2[5H]-furanones as possible signaling molecules in Lactobacillus helveticus
    Maurice Ndagijimana
    Dipartimento Scienze degli Alimenti, Alma Mater Studiorum, University of Bologna, Via Fanin 46, 40127 Bologna, Italy
    Appl Environ Microbiol 72:6053-61. 2006
    ..cremoris or to those identified in some cheeses with Lactobacillus helveticus as a starter culture...
  83. ncbi Introducing glutathione biosynthetic capability into Lactococcus lactis subsp. cremoris NZ9000 improves the oxidative-stress resistance of the host
    Rui Yan Fu
    The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, People s Republic of China
    Metab Eng 8:662-71. 2006
    ..We conclude that the resistance of L. lactis subsp. cremoris NZ9000 to oxidative stress can be increased in engineered cells with glutathione producing capability...
  84. ncbi [Purulent pleurisy due to lactococcus lactis cremoris]
    A Mofredj
    Rev Mal Respir 23:485-6. 2006
  85. pmc Identification of a gene required for maturation of an extracellular lactococcal serine proteinase
    A J Haandrikman
    Department of Genetics, University of Groningen, The Netherlands
    J Bacteriol 171:2789-94. 1989
    ..Furthermore, deletion of the 130 C-terminal amino acids of the Wg2 proteinase prevented attachment of the enzyme to lactococcal cells...
  86. ncbi Characterization of LlaCI, a new restriction-modification system from Lactococcus lactis subsp. cremoris W15
    A Madsen
    Department of Dairy and Food Science, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark
    Biol Chem 379:443-9. 1998
    ..It shows 24% identity to the HindIII endonuclease...
  87. pmc Complete genome sequence of Lactococcus lactis subsp. cremoris A76
    Alexander Bolotin
    INRA, AgroParisTech, UMR1319 MICALIS, Jouy en Josas, France
    J Bacteriol 194:1241-2. 2012
    ..lactis subsp. lactis rather than to the L. lactis subsp. cremoris lineage. This indicates the existence of genetic exchange between the diverse subspecies, presumably related to the technological process...
  88. doi Dried tomato-flavored probiotic cream cheese with Lactobacillus paracasei
    Marilsa S S Santini
    Univ Norte do Paraná UNOPAR, Mestrado em Ciência e Tecnologia do Leite, Av Paris, 375, 86041 140, Londrina, PR, Brazil
    J Food Sci 77:M604-8. 2012
    ..Cream cheeses C and P did not differ on the sensory tests, both obtaining good overall acceptance by the consumers, of which 82.6% stated that they certainly or probably would buy the product...
  89. pmc Design and Construction of a Single-Tube, LATE-PCR, Multiplex Endpoint Assay with Lights-On/Lights-Off Probes for the Detection of Pathogens Associated with Sepsis
    Rachel K Carver-Brown
    Department of Biology, Brandeis University, Waltham, MA 02453 2728, USA
    J Pathog 2012:424808. 2012
    ..Significance and Impact of the Study. This assay uses new technology to achieve an advance in the field of molecular diagnostics: a single-tube multiplex assay for identification of pathogens commonly associated with sepsis...
  90. doi Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase
    Jiangfeng Ma
    State Key Laboratory of Materials Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, 211816, Jiangsu, China
    Appl Microbiol Biotechnol 97:6739-47. 2013
    ..Furthermore, when the reducing agent dithiothreitol or reduced carbon source sorbitol was added, the cell growth and carbon source consumption rate of BA016 was reasonably enhanced and succinate productivity increased...
  91. doi pDB2011, a 7.6 kb multidrug resistance plasmid from Listeria innocua replicating in Gram-positive and Gram-negative hosts
    David Bertsch
    Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich, Switzerland
    Plasmid 70:284-7. 2013
    ..This study reports the first multidrug resistance plasmid in L. innocua. A large potential for dissemination of pDB2011 is indicated by its host range of both Gram-positive and Gram-negative bacteria...
  92. doi Cloning, production, and functional expression of the bacteriocin sakacin A (SakA) and two SakA-derived chimeras in lactic acid bacteria (LAB) and the yeasts Pichia pastoris and Kluyveromyces lactis
    Juan J Jimenez
    Departamento de Nutricion, Bromatologia y Tecnologia de los Alimentos, Facultad de Veterinaria, Universidad Complutense de Madrid UCM, Avenida Puerta de Hierro, S N, 28040, Madrid, Spain
    J Ind Microbiol Biotechnol 40:977-93. 2013
    ....
  93. ncbi Nonidentity between plasmid and chromosomal copies of ISS1-like sequences in Lactococcus lactis subsp. lactis CNRZ270 and their possible role in chromosomal integration of plasmid genes
    D C Huang
    Laboratoire de Genetique Microbienne, Universite de Caen, France
    Gene 118:39-46. 1992
    ..ISS1-like sequences were also found on plasmids of numerous Lc. lactis strains, as well as one out of seven Lactobacillus (Lb.) casei and one out of three Lb. plantarum strains examined...
  94. pmc Phage abortive infection mechanism from Lactococcus lactis subsp. lactis, expression of which is mediated by an Iso-ISS1 element
    P J Cluzel
    Laboratoire de Genetique Microbienne, Institut de Biotechnologie, I N R A, Jouy en Josas, France
    Appl Environ Microbiol 57:3547-51. 1991
    ..The expression of abi-416 was shown to be mediated by the Iso-ISS1 element, which contains a sequence fitting the consensus sequence for gram-positive promoters...
  95. pmc Characterization of phiLC3, a Lactococcus lactis subsp. cremoris temperature bacteriophage with cohesive single-stranded DNA ends
    D Lillehaug
    Laboratory of Microbial Gene Technology, Oslo, Norway
    Appl Environ Microbiol 57:3206-11. 1991
    ..This result indicates that lysogeny involves integration of the phage into the host chromosome. A spontaneous phiLC3 clear plaque mutant that was unable to give rise to lysogens was isolated...
  96. pmc Organization and nucleotide sequences of two lactococcal bacteriocin operons
    M J van Belkum
    Department of Genetics, University of Groningen, Haren, The Netherlands
    Appl Environ Microbiol 57:492-8. 1991
    ..The second ORF, containing 98 codons, specified immunity. The nucleotide sequences of both fragments upstream of the first ORFs as well as the first 20 bp of the first ORF of both bacteriocin operons appeared to be identical...
  97. pmc Lactococcal proteinase maturation protein PrtM is a lipoprotein
    A J Haandrikman
    Department of Genetics, University of Groningen, Haren, The Netherlands
    J Bacteriol 173:4517-25. 1991
    ..This mutation did not affect proteinase activity...
  98. pmc Molecular characterization of promoters of the Lactococcus lactis subsp. cremoris temperate bacteriophage BK5-T and identification of a phage gene implicated in the regulation of promoter activity
    G Lakshmidevi
    Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, Victoria, Australia
    Appl Environ Microbiol 56:934-42. 1990
    ..This region has been designated bpi (for BK5-T promoter inhibitor)...
  99. pmc Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2
    J Kok
    Institute of Genetics, University of Groningen, Haren, The Netherlands
    Appl Environ Microbiol 54:231-8. 1988
    A 6.5-kilobase HindIII fragment that specifies the proteolytic activity of Streptococcus cremoris Wg2 was sequenced entirely...
  100. ncbi Citrate utilization gene cluster of the Lactococcus lactis biovar diacetylactis: organization and regulation of expression
    F Lopez de Felipe
    Centro de Investigaciones Biologicas, C S I C, Velazquez, Madrid, Spain
    Mol Gen Genet 246:590-9. 1995
    ..We propose that expression of the cit cluster is controlled at the post-transcriptional level by mRNA processing at a putative complex secondary structure and by translational repression mediated by CitR...
  101. pmc Cloning and characterization of upp, a gene encoding uracil phosphoribosyltransferase from Lactococcus lactis
    J Martinussen
    Center for Lactic Acid Bacteria, Laboratory of Microbiology, Technical University of Denmark, Lyngby
    J Bacteriol 176:6457-63. 1994
    ..Secondary mutants in thymidine phosphorylase and thymidine kinase were isolated by selection for resistance to high concentrations of 5-fluorouracil...

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