Genomes and Genes
Publications271 found, 100 shown here
- Human Health and the Biological Effects of Tritium in Drinking Water: Prudent Policy Through Science - Addressing the ODWAC New RecommendationS Dingwall
Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, ON, Can, L8S 4K1
Dose Response 9:6-31. 2011..The radiation doses to humans and non-human biota from these releases are low and orders of magnitude less than doses received from naturally occurring ..
- Antagonism of TCDD-induced ethoxyresorufin-O-deethylation activity by polybrominated diphenyl ethers (PBDEs) in primary cynomolgus monkey (Macaca fascicularis) hepatocytesA K Peters
Institute for Risk Assessment Sciences IRAS, Utrecht University, Yalelaan 2, PO Box 80176, 3508 TD Utrecht, The Netherlands
Toxicol Lett 164:123-32. 2006..PBDEs) are widespread environmental pollutants, and the levels of certain congeners have been increasing in biota and abiota in recent decades...
- Persistent organic pollutants and metals in the freshwater biota of the Canadian Subarctic and Arctic: an overviewMarlene S Evans
National Water Research Institute, Environment Canada, 11 Innovation Boulevard, Saskatoon, SK, Canada S7N 3H5
Sci Total Environ 351:94-147. 2005Over 1999-2002, an extensive series of contaminant studies was conducted on freshwater biota of Canada's Arctic and Subarctic regions. The majority of inorganic contaminant studies focused on mercury and fish...
- Cyanobacterial toxins: a qualitative meta-analysis of concentrations, dosage and effects in freshwater, estuarine and marine biotaBas W Ibelings
Netherlands Institute of Ecology NIOO KNAW Centre for Limnology, Rijksstraatweg 6, 3631 AC, Nieuwersluis, The Netherlands
Adv Exp Med Biol 619:675-732. 2008..the presence (concentrations) of different cyanobacterial toxins in the tissues of various groups of aquatic biota after exposure via different routes, experimentally in the lab or via natural routes in the environment...
- Levels of polybrominated diphenyl ether (PBDE) flame retardants in animals representing different trophic levels of the North Sea food WebJan P Boon
Royal Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
Environ Sci Technol 36:4025-32. 2002..BDE209 is often the major BDE congener in sediments from the area, the main reason for its low concentrations in biota from the North Sea seems to be a relatively low bioaccumulation potential...
- Long-range atmospheric transport of three toxaphene congeners across Europe. Modeling by chained single-box FATEMOD programJaakko Paasivirta
Department of Chemistry, University of Jyvaskyla, P O Box 35, 40014, Jyvaskyla, Finland
Environ Sci Pollut Res Int 16:191-205. 2009..Polychlorobornanes analyzed in biota of the Barents Sea offered one case to study this modeling alternative, while toxaphene has been and partly still ..
- Marine biodiversity of Aotearoa New ZealandDennis P Gordon
National Institute of Water and Atmospheric Research, Kilbirnie, Wellington, New Zealand
PLoS ONE 5:e10905. 2010..Knowledge of the marine biota is based on more than 200 years of marine exploration in the region...
- A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysisAndrew C Rastall
Institute of Hygiene and Medical Microbiology, University of Heidelberg, Germany
Environ Sci Pollut Res Int 13:256-67. 2006..posses the capacity to disrupt endogenous control of developmental and reproductive processes in aquatic biota by activating estrogen receptors...
- Spatial and temporal trends and effects of contaminants in the Canadian Arctic marine ecosystem: a reviewD Muir
National Water Research Institute, Environment Canada, Burlington, ON, Canada
Sci Total Environ 230:83-144. 1999..This paper reviews the current state of knowledge of contaminants in marine biota in the Canadian Arctic and where possible, discusses biological effects...
- Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fishRobert J Letcher
Wildlife and Landscape Science Directorate, Science and Technology, Branch, Environment Canada, Carleton University, Ottawa, ON, Canada
Sci Total Environ 408:2995-3043. 2010..compounds (PFCs) including perfluorooctane sulfonate (PFOS) and perfluorooctanic acid (PFOA) found in Arctic biota and humans...
- Evidence for unique and ubiquitous environmental sources of 3,3'-dichlorobiphenyl (PCB 11)Lisa A Rodenburg
Department of Environmental Sciences, Rutgers University, 14 College Farm, Road, New Brunswick, New Jersey 08901, USA
Environ Sci Technol 44:2816-21. 2010The non-Aroclor congener 3,3'-dichlorobiphenyl (PCB 11) has been recently detected in air, water, biota, sediment, and suspended sediment...
- The effect of water hardness on the toxicity of uranium to a tropical freshwater alga Chlorella spAmanda L Charles
Environment Division, Australian Nuclear Science and Technology Organisation, PMB 1, Menai NSW 2234, Australia
Aquat Toxicol 60:61-73. 2002Uranium (U) derived from mining activities is of potential ecotoxicological concern to freshwater biota in tropical northern Australia...
- Environmental factors determining the trace-level sorption of silver and thallium to soilsAstrid R Jacobson
Department of Crop and Soil Sciences, Cornell University, Bradfield Hall, Ithaca, NY 14853 1901, USA
Sci Total Environ 345:191-205. 2005Silver (Ag) and thallium (Tl) are nonessential elements that can be highly toxic to a number of biota even when present in the environment at trace levels...
- Spatial and temporal trends of contaminants in Canadian Arctic freshwater and terrestrial ecosystems: a reviewB Braune
Canadian Wildlife Service, Environment Canada, National Wildlife Research Center, Ottawa, ON, Canada
Sci Total Environ 230:145-207. 1999The state of knowledge of contaminants in Canadian Arctic biota of the freshwater and terrestrial ecosystems has advanced enormously since the publication of the first major reviews by Lockhart et al. and Thomas et al...
- Twentieth century overview of heavy metals in the Galician Rias (NW Iberian Peninsula)R Prego
Marine Biogeochemistry Research Group, Instituto de Investigaciones Marinas CSIC C Eduardo Cabello, n6, E 36208 Vigo, Spain
Environ Pollut 121:425-52. 2003..Data of heavy metals in the dissolved phase, suspended particulate matter and biota is scarce in the mainstream literature and should be considered in the future research...
- Environmental fate and global distribution of polychlorinated biphenylsAngelika Beyer
Department of Analytical Chemistry, Chemical Faculty, Gdansk University of Technology, G Narutowicza Street 11 12, 80 233 Gdansk, Poland
Rev Environ Contam Toxicol 201:137-58. 2009..and industry have all paid increasing attention to the crucial task of determining how xenobiotic exposures affect biota populations, communities, or entire ecosystems...
- Nonstarter Lactobacillus strains as adjunct cultures for cheese making: in vitro characterization and performance in two model cheesesM Briggiler-Marcó
Instituto de Lactología Industrial Facultad de Ingeniería Química, Universidad Nacional del Litoral CONICET Santiago del Estero 2829, S3000AOM Santa Fe, Argentina
J Dairy Sci 90:4532-42. 2007..from nonstarter lactic acid bacteria origin appear as the best alternative to indirectly control cheese biota. The objective of the present work was to study the technological properties of Lactobacillus strains isolated ..
- Stable carbon and nitrogen isotope signatures indicate recovery of marine biota from sewage pollution at Moa Point, New ZealandKaryne M Rogers
Institute of Geological and Nuclear Sciences Limited, 30 Gracefield Road, P O Box 31312, Lower Hutt, New Zealand
Mar Pollut Bull 46:821-7. 2003....
- Biological and remote sensing perspectives of pigmentation in coral reef organismsJohn D Hedley
Tropical Coastal Management Studies, Department of Marine Sciences and Coastal Management, Ridley Building, University of Newcastle, NE1 7RU, UK
Adv Mar Biol 43:277-317. 2002..Sources of pigmentation in reef biota are reviewed together with remote sensing studies where spectral discrimination has been effectively demonstrated ..
- Biodiversity of lactic acid bacteria and yeasts in spontaneously-fermented buckwheat and teff sourdoughsAlice V Moroni
School of Food and Nutritional Sciences, University College Cork, Western Road, Cork, Ireland
Food Microbiol 28:497-502. 2011..The fermentations were initiated by the spontaneous biota of the flours and developed under two technological conditions (A and B)...
- Enantiomer-specific biomagnification of alpha-hexachlorocyclohexane and selected chiral chlordane-related compounds within an Arctic marine food webPaul F Hoekstra
University of Guelph, Department of Environmental Biology, Environment Canada, National Water Research Institute, Burlington, Ontario, Canada
Environ Toxicol Chem 22:2482-91. 2003..metabolites (oxychlordane [OXY] and heptachlor exo-epoxide [HEPX]), were quantified in seawater (100 L; n = 6) and biota from the coastal Beaufort-Chukchi Seas food web near Barrow (AK, USA). The biota included zooplankton (Calanus spp...
- Agricultural soil as a potential source of input of organochlorine pesticides into a nearby pondKarina S B Miglioranza
Laboratorio de Ecotoxicologia, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, Argentina
Environ Sci Pollut Res Int 9:250-6. 2002..Argentina, to assess an agricultural soil as a potential source of organochlorine (OC) pesticides for the aquatic biota of a nearby pond...
- ENCORE: the effect of nutrient enrichment on coral reefs. Synthesis of results and conclusionsK Koop
School of Biological Sciences, University of Sydney, Sydney, NSW 2006, Australia
Mar Pollut Bull 42:91-120. 2001..have been demonstrated in the laboratory, there is little direct evidence of nutrient effects on coral reef biota in situ...
- Chlorinated hydrocarbons in marine biota and coastal sediments from the Gulf and Gulf of OmanStephen de Mora
Marine Environment Laboratory, International Atomic Energy Agency, 4 Quai Antoine 1er, MC 98000, Monaco
Mar Pollut Bull 50:835-49. 2005..distribution of various organochlorinated compounds was investigated in the Gulf and Gulf of Oman based on marine biota (fish and various bivalves) and coastal sediment collected in Bahrain, Oman, Qatar and the United Arab Emirates (..
- Seasonal differences in mercury accumulation in Trichiurus lepturus (Cutlassfish) in relation to length and weight in a Northeast Brazilian estuaryMonica Ferreira Costa
Departamento de Oceanografia, Universidade Federal de Pernambuco, CEP 50740 550, Recife, Brazil
Environ Sci Pollut Res Int 16:423-30. 2009..for seasonal changes in bioavailability of mercury (Hg) and other pollutants to the estuarine and coastal biota. Mercury bioaccumulates along estuarine-marine food chains usually result in higher concentrations in tissues of ..
- Distribution of (226)Ra-(210)Pb-(210)Po in marine biota and surface sediments of the Red Sea, SudanD A Sirelkhatim
Sudan Atomic Energy Commission, Environmental Monitoring, Khartoum, Sudan
J Environ Radioact 99:1825-8. 2008..97) and the brown algae Sargassum (1.85) have a greater tendency to accumulate (210)Po over (210)Pb, while in the rest of species; this ratio is less than unity...
- Comparison of storm intensity and application timing on modeled transport and fate of six contaminantsErica D Chiovarou
Center for Coastal Environmental Health and Biomolecular Research, National Ocean Service, National Oceanic and Atmospheric Administration, 219 Fort Johnson Road, Charleston, SC 29412 9110, USA
Sci Total Environ 389:87-100. 2008..The Pesticide Root Zone Model and the Exposure Analysis Modeling System were used to compare risk to resident biota in estuarine headwaters in two locations under various conditions...
- Speciation analysis of antimony in marine biota by HPLC-(UV)-HG-AFS: Extraction procedures and stability of antimony speciesIda De Gregori
Laboratorio de Química Analítica y Ambiental, Instituto de Quimica, Pontificia Universidad Catolica de Valparaiso, Valparaiso, Chile
Talanta 73:458-65. 2007Speciation analysis of antimony in marine biota is not well documented, and no specific extraction procedure of antimony species from algae and mollusk samples can be found in the literature...
- Persistent organic pollutants and mercury in marine biota of the Canadian Arctic: an overview of spatial and temporal trendsB M Braune
National Wildlife Research Centre, Canadian Wildlife Service, Environment Canada, Carleton University Raven Road, Ottawa, ON, Canada K1A 0H3
Sci Total Environ 351:4-56. 2005..of data which was generated on mercury (Hg) and persistent organic pollutants (POPs) in Canadian Arctic marine biota since the first Canadian Arctic Contaminants Assessment Report (CACAR) was published in 1997...
- Evaluation of surface water quality using an ecotoxicological approach: a case study of the Alqueva Reservoir (Portugal)Patricia Palma
Departamento de Ciências do Ambiente, Escola Superior Agrária de Beja, Rua Pedro Soares, Apartado 6158, Beja, 7801 908, Portugal
Environ Sci Pollut Res Int 17:703-16. 2010..Because of that, no information is available on the possible impact of pollutants on the biota. The surface water toxicity was assessed using acute and chronic bioassays...
- Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milkAnneli Marklund Sundkvist
Department of Chemistry, Umea University, Umea, Sweden
J Environ Monit 12:943-51. 2010..Some of the biota samples were collected at locations with known potential sources of OPs, but most were collected in background ..
- Biomonitoring of lead, zinc, and cadmium in streams draining lead-mining and non-mining areas, southeast Missouri, USAJohn M Besser
US Geological Survey, Columbia Environmental Research Center, 4200 New Haven Road, Columbia, MO 65201, USA
Environ Monit Assess 129:227-41. 2007We evaluated exposure of aquatic biota to lead (Pb), zinc (Zn), and cadmium (Cd) in streams draining a Pb-mining district in southeast Missouri...
- Scientific research, stakeholders, and policy: continuing dialogue during research on radionuclides on Amchitka Island, AlaskaJoanna Burger
Division of Life Sciences, Consortium for Risk Evaluation with Stakeholder Participation, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854 8082, USA
J Environ Manage 85:232-44. 2007..We use a large study of potential radionuclide levels in marine biota around Amchitka Island as a case study...
- Biomonitoring study of heavy metals in biota and sediments in the South Eastern coast of Mediterranean sea, EgyptMaha A M Abdallah
National Institute of Oceanography and Fisheries, Marine Pollution Lab, Alexandria, Egypt
Environ Monit Assess 146:139-45. 2008Concentrations of Cd, Cu, Co, Zn, Mn and Fe were determined in biota and sediment samples collected from the Eastern Harbour and El-Mex Bay in the Mediterranean Sea, Egypt...
- Changes in microbial community structure and function within particle size fractions of a paddy soil under different long-term fertilization treatments from the Tai Lake region, ChinaPingjiu Zhang
Institute of Resources, Ecosystem and Environment of Agriculture, Nanjing Agricultural University, Nanjing 210095, China
Colloids Surf B Biointerfaces 58:264-70. 2007..Soil particle size fractions (PSFs) of different sizes act as soil microhabitats for different kinds of microbial biota with varying conditions of redox reactions and soil organic matter (SOC) substrates...
- Polybrominated diphenyl ethers and organochlorine compounds in biota from the marine environment of East GreenlandKatrin Vorkamp
Department of Environmental Chemistry and Microbiology, National Environmental Research Institute, Frederiksborgvej 399, Roskilde, Denmark
Sci Total Environ 331:143-55. 2004..g. BDE28 and BDE47 than black guillemots. The reasons for these different accumulation patterns are largely unknown and may reflect species-related differences in pollutant exposure, bioavailablity and metabolism...
- Toxicity of selected pharmaceuticals to the anostracan crustacean Thamnocephalus platyurus: comparison of sublethal and lethal effect levels with the 1h Rapidtoxkit and the 24h Thamnotoxkit microbiotestsGrzegorz Nałęcz-Jawecki
Department of Environmental Health Sciences, Medical University of Warsaw, Warsaw, Poland
Environ Sci Pollut Res Int 13:22-7. 2006..amount of information on the potential hazard of the ever increasing amounts of drugs in surface waters to aquatic biota, a study was undertaken to determine the effect levels of 28 selected pharmaceuticals to the crustacean test ..
- Congener pattern of hexabromobiphenyls in marine biota from different proveniencesRoland von der Recke
University of Hohenheim, Institute of Food Chemistry 170b, Stuttgart, Germany
Sci Total Environ 393:358-66. 2008..Most of these PBBs were determined for the first time in marine biota and must be metabolites of higher brominated PBBs since they were not present in any technical product...
- Occurrence of organic wastewater and other contaminants in cave streams in northeastern Oklahoma and northwestern ArkansasJoseph R Bidwell
Department of Zoology, Oklahoma State University, Stillwater, OK 74078, USA
Arch Environ Contam Toxicol 58:286-98. 2010..might be transported to groundwater and, ultimately, cave ecosystems, where they might impact resident biota. In this study, polar organic chemical integrative samplers (POCISs) and semipermeable membrane devices (SPMDs) ..
- Brominated flame retardants in the Arctic environment--trends and new candidatesCynthia A de Wit
Department of Applied Environmental Science ITM, Stockholm University, Stockholm, Sweden
Sci Total Environ 408:2885-918. 2010..ubiquitous in the Arctic, with the gamma-HBCD isomer predominating in air, the alpha-HBCD isomer predominating in biota and similar concentrations of alpha-, beta- and gamma-HBCD found in marine sediments...
- Ribosomal DNA sequence analysis of mucosa-associated bacteria in Crohn's diseaseTom Prindiville
Division of Gastroenterology, University of California at Davis, Sacramento, California 95817, USA
Inflamm Bowel Dis 10:824-33. 2004..Enteric bacteria are implicated in the pathogenesis of Crohn's disease (CD); however, no specific causative organisms have been identified...
- Non-effect of water hardness on the accumulation and toxicity of copper in a freshwater macrophyte (Ceratophyllum demersum): how useful are hardness-modified copper guidelines for protecting freshwater biota?Scott J Markich
Aquatic Solutions International, Level 1, 467 Miller St, Cammeray, NSW 2062, Australia
Chemosphere 65:1791-800. 2006Several nations have adopted hardness-modified copper (Cu) guidelines for protecting freshwater biota. However, there is a lack of good quality data and mechanistic understanding on the effects of true water hardness (calcium (Ca) and ..
- A comparison of model performance for six quantitative structure-activity relationship packages that predict acute toxicity to fishDwayne R J Moore
The Cadmus Group, Suite 204, 411 Roosevelt Avenue, Ottawa, Ontario K2A 3X9, Canada
Environ Toxicol Chem 22:1799-809. 2003..regulatory programs rely on quantitative structure-activity relationship (QSAR) models to predict toxic effects to biota. Many currently existing QSAR models can predict the effects of a wide range of substances to biota, particularly ..
- Muscle metabolism and growth in Antarctic fishes (suborder Notothenioidei): evolution in a cold environmentIan A Johnston
Gatty Marine Laboratory, School of Biology, University of St Andrews, St Andrews, Fife, Scotland, KY16 8LB, UK
Comp Biochem Physiol B Biochem Mol Biol 136:701-13. 2003..86 degrees C. Origins and Evolution of the Antarctic Biota Geological Society Special Publication No. 47, Geological Society of London. pp. 253-268)...
- Role of sea-ice biota in nutrient and organic material cycles in the northern Baltic SeaJorma Kuparinen
Department of Biological and Environmental Sciences, University of Helsinki, Finland
Ambio 36:149-54. 2007....
- Response of zooplankton and phytoplankton communities to creosote-impregnated Douglas fir pilings in freshwater microcosmsP K Sibley
Department of Environmental Biology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
Arch Environ Contam Toxicol 47:56-66. 2004..information by which to judge the potential for creosote leached from impregnated pilings to cause toxicity to biota in aquatic environments...
- Toxicity of selenium and other elements in food organisms to razorback sucker larvaeSteven J Hamilton
Biological Resources Division, U S Geological Survey, Columbia Environmental Research Center, Field Research Station, 31247 436th Avenue, Yankton, SD 57078 6364, USA
Aquat Toxicol 59:253-81. 2002Elevated selenium concentrations documented in water, sediment, and biota in irrigation drain water studies by U.S...
- Derivation of a chronic site-specific water quality standard for selenium in the Great Salt Lake, Utah, USAKevin V Brix
EcoTox, 721 Navarre Avenue, Coral Gables, Florida 33134, USA
Environ Toxicol Chem 23:606-12. 2004..The study examined the bioavailability and toxicity of selenium, as selenate, to biota resident to the Great Salt Lake and the potential for dietary selenium exposure to aquatic dependent birds that ..
- Preliminary assessment of polybrominated diphenyl ethers (PBDEs) in the Scottish aquatic environment, including the Firth of ClydeL Webster
Fisheries Research Services Marine Laboratory, 375 Victoria Road, Aberdeen, Scotland, UK, AB11 9DB
J Environ Monit 10:463-73. 2008..Sediment and biota (fish liver, fish muscle and mussels) from a number of locations around Scotland were analysed for PBDEs with ..
- Teratogenicity and embryotoxicity in aquatic organisms after pesticide exposure and the role of oxidative stressVeronika Paskova
Faculty of Science, Research Centre for Toxic Compounds in the Environment RECETOX, Masaryk University, Kamenice, Brno, Czech Republic
Rev Environ Contam Toxicol 211:25-61. 2011Many pesticides have been documented to induce embryotoxicity and teratogenicity in non-target aquatic biota such a fish, amphibians and invertebrates...
- Enhancement of tritium concentrations on uptake by marine biota: experience from UK coastal watersG J Hunt
Centre for Environment, Fisheries and Aquaculture Science, Lowestoft NR33 0HT, UK
J Radiol Prot 30:73-83. 2010Concentrations of tritium in sea water and marine biota as reported over the last approximately 10 years from monitoring programmes carried out by this laboratory under contract to the UK Food Standards Agency are reviewed from three ..
- Changes in contaminant levels in New Jersey osprey eggs and prey, 1989 to 1998K E Clark
New Jersey Division of Fish and Wildlife, Trenton 08625, USA
Arch Environ Contam Toxicol 40:277-84. 2001..of the health of estuarine areas because they feed almost exclusively on fish with the balance on other aquatic biota. Through the 1980s, ospreys nesting on Delaware Bay in New Jersey had reduced reproductive success relative to ..
- Pillars of Hercules: is the Atlantic-Mediterranean transition a phylogeographical break?Tomaso Patarnello
Dipartimento di Sanità Pubblica Patologia Comparata e Igiene Veterinaria, Agripolis, Universita di Padova, Viale dell Universita, 16, I 35020 Legnaro PD, Italy
Mol Ecol 16:4426-44. 2007..as there are discordant results regarding the biogeographical separation between the Atlantic and Mediterranean biota. The opening of the Strait of Gibraltar at the end of the Messinian Salinity Crisis (some 5...
- Occurrence of phthalates in sediment and biota: relationship to aquatic factors and the biota-sediment accumulation factorPo Chin Huang
Department of Environmental and Occupational Health, Medical College, National Cheng Kung University, 138 Sheng Li Road, Tainan 704, Taiwan, ROC
Chemosphere 73:539-44. 2008..in 17 Taiwan's rivers to determine the relationships between phthalate levels in sediment and aquatic factors, and biota-sediment accumulation factor (BSAF) for phthalates...
- Prognosis for ecosystem recovery following rodent eradication and seabird restoration in an island archipelagoHolly P Jones
Yale University, 370 Prospect St, New Haven, Connecticut 06511, USA
Ecol Appl 20:1204-16. 2010Invasive species are widespread and can have devastating effects on biota, especially insular biota. Invasive species eradications are increasingly employed to promote island recovery to preinvasion states...
- Blood parasites in birds from MadagascarAmy F Savage
Department of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, Box 110880, Gainesville, Florida 32611, USA
J Wildl Dis 45:907-20. 2009Madagascar has long been recognized for its unique and diverse biota. In particular, significant effort has been made to establish baseline population data to better conserve the endemic avifauna...
- Perfluorinated acids in Arctic snow: new evidence for atmospheric formationCora J Young
Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario, Canada M5S 3H6, CLF Chem Consulting, 28 Rue Edouard Olivier, Brussels, Belgium
Environ Sci Technol 41:3455-61. 2007Perfluorinated acids (PFAs) are ubiquitously found in water and biota, including remote regions such as the High Arctic...
- A summary of total mercury concentrations in flora and fauna near common contaminant sources in the Gulf of MexicoM Lewis
United States Environmental Protection Agency, National Health and Environmental Effects, Research Laboratory, Gulf Ecology Division, Gulf Breeze, FL 32561, USA
Chemosphere 70:2016-24. 2008Total mercury concentrations are summarized for environmental media and biota collected from near-coastal areas, several impacted by contaminant sources common to the Gulf of Mexico...
- An evaluation of the success of dredging as remediation at a DDT-contaminated site in San Francisco Bay, California, USADonald P Weston
University of California, Department of Integrative Biology, Berkeley 94720 3140, USA
Environ Toxicol Chem 21:2216-24. 2002..the success of the dredging based largely on body burdens of DDT and its metabolites (sigmaDDT) in resident biota, with some data on sediment- and water-contaminant levels and sediment toxicity testing...
- The precipitation of mucin by aluminiumC Exley
Birchall Centre for Inorganic Chemistry and Materials Science, Department of Chemistry, Keele University, Staffordshire, UK
J Inorg Biochem 70:195-206. 1998..Considering the ubiquitous nature of mucin and the degree to which it is conserved within biota the interactions of Al with mucin may have wide ranging implications for biological systems.
- Umbrellas and flagships: efficient conservation surrogates or expensive mistakes?S J Andelman
National Center for Ecological Analysis and Synthesis, 735 State Street, Suite 300, Santa Barbara, CA 93101, USA
Proc Natl Acad Sci U S A 97:5954-9. 2000The use of umbrella and flagship species as surrogates for regional biota whose spatial distributions are poorly known is a popular conservation strategy. Yet many assumptions underlying the choice of surrogate species remain untested...
- The high oxygen atmosphere toward the end-Cretaceous; a possible contributing factor to the K/T boundary extinctions and to the emergence of C(4) speciesJ Gale
Department of Plant Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
J Exp Bot 52:801-9. 2001..The weakened biota would have been predisposed to the consequences of volcanism and the K/T boundary bolide impact...
- Biota participating in wastewater treatment in a horizontal flow constructed wetlandJ Vymazal
Ecology and Use Wetlands, Praha, Czech Republic
Water Sci Technol 44:211-4. 2001..b>Biota of the inflowing water is usually restricted to bacteria, ciliata and colorless flagellata while the organisms ..
- Pollen movement in declining populations of California Valley oak, Quercus lobata: where have all the fathers gone?V L Sork
Department of Biology, University of Missouri, St Louis 90095, USA
Mol Ecol 11:1657-68. 2002..is a widely distributed, endemic species in California, increasingly jeopardized by anthropogenic changes in biota and land use...
- Quantifying population recovery rates for ecological risk assessmentLawrence W Barnthouse
LWB Environmental Services, 105 Wesley Lane, Oak Ridge, Tennessee 37830, USA
Environ Toxicol Chem 23:500-8. 2004..Recovery models are developed for aquatic biota ranging in size and longevity from unicellular algae to fish and turtles...
- A unique cross section through the skin of the dinosaur Psittacosaurus from China showing a complex fibre architectureTheagarten Lingham-Soliar
School of Biological and Conservation Sciences, University of KwaZulu Natal, Private Bag X54001, Durban 4000, Republic of South Africa
Proc Biol Sci 275:775-80. 2008..of soft tissues in the ventrolateral region of the plant-eating dinosaur Psittacosaurus from the Jehol biota of China...
- Temporal changes in the distribution, methylation, and bioaccumulation of newly deposited mercury in an aquatic ecosystemDiane M Orihel
Clayton H Riddell Faculty of Environment, Earth, and Resources, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada
Environ Pollut 154:77-88. 2008..We suggest that reductions in atmospheric Hg deposition should lead to decreases in MeHg concentrations in biota, but that changes will be more easily detected in short-lived pelagic species than long-lived species associated ..
- Birth of a biome: insights into the assembly and maintenance of the Australian arid zone biotaM Byrne
Science Division, Department of Environment and Conservation, Locked Bag 104, Bentley Delivery Centre, WA 6983, Australia
Mol Ecol 17:4398-417. 2008..is one of the largest desert landform systems in the world, with a unique, diverse and relatively well-studied biota. With foci on palaeoenvironmental and molecular data, we here review what is known about the assembly and ..
- Organic contaminants in the marine environment of Manila Bay, PhilippinesFernando P Carvalho
Marine Environment Laboratories, International Atomic Energy Agency, 4 Quai Antoine 1er, MC 98000, Monaco
Arch Environ Contam Toxicol 57:348-58. 2009..Nevertheless, current concentrations of persistent organochlorine contaminants in sediments were under threshold effect levels (TELs) and chronic toxic effects are, thus, unlikely to generate impairment of marine biota in Manila Bay.
- Amphipod intersex, metals and latitude: a perspectiveM Ramiro Pastorinho
1 Center for Environmental and Marine Studies CESAM and Department of Biology, University of Aveiro, Campus de Santiago, 3810 193 Aveiro, Portugal
Mar Pollut Bull 58:812-7. 2009..Nevertheless, water, biota and sediment samples pointed to equivalent metal levels, and in consonance the prevalence of intersex was not ..
- Enantioselective acute toxicity and bioaccumulation of benalaxyl in earthworm (Eisenia fedtia)Peng Xu
Department of Applied Chemistry, China Agricultural University, Beijing 100193, China
J Agric Food Chem 57:8545-9. 2009..Peak-shaped accumulation curves were observed for both enantiomers, and the calculated biota to soil accumulations (kg dry kg(-1) wet weight) at steady state were below 1 for both enantiomers...
- Trophic transfer of arsenic and antimony in a freshwater ecosystem: a field studyJulia Laurence Culioli
Laboratoire Sciences Pour l Environnement, Equipe Hydrobiologie, UMR CNRS 6134, Faculte des Sciences et Techniques, Université de Corse Pascal Paoli, BP 52, F 20 250 Corte, France
Aquat Toxicol 94:286-93. 2009..We determined levels of arsenic and antimony in the water and the biota (bryophytes, benthic macroinvertebrates and fish), along a pollution gradient...
- Effects of a physico-chemical treatment of a dredged sediment on its ecotoxicity after discharge in laboratory gravel pit microcosmsBernard Clement
Université de Lyon Ecole Nationale des Travaux Publics de l Etat, Laboratoire des Sciences de l Environnement, Rue Maurice Audin, 69517 Vaulx en Velin Cedex, France
J Hazard Mater 175:205-15. 2010..a high solid:liquid ratio (1:10) in gravel pits or equivalent aquatic ecosystems may have only limited effects on biota and ground water quality...
- Perfluorooctane sulfonate (PFOS) precursors can be metabolized enantioselectively: principle for a new PFOS source tracking toolYuan Wang
Division of Analytical and Environmental Toxicology, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada, T6G 2G3
Environ Sci Technol 43:8283-9. 2009..issue facing both the scientific and chemical regulatory communities is the extent to which PFOS concentrations in biota are attributable to direct exposure versus metabolism of PFOS-precursors (higher molecular weight derivatives that ..
- Twenty years of elemental analysis of marine biota within the German Environmental Specimen Bank--a thorough look at the dataHeinz Rüdel
Fraunhofer Institute for Molecular Biology and Applied Ecology Fraunhofer IME, 57377, Schmallenberg, Germany
Environ Sci Pollut Res Int 17:1025-34. 2010..This is done exemplarily for the heavy metals cadmium (Cd), mercury (Hg), and lead (Pb) in marine specimens of the Baltic and the North Sea...
- The usefulness of a threat and disturbance categorization developed for Queensland wetlands to environmental management, monitoring, and evaluationA J J Lynch
Environmental Information Systems Unit, Department of Environment and Resource Management, Brisbane City East, QLD 4002, Australia
Environ Manage 47:40-55. 2011..a systematic framework and categorization demonstrates the importance and usefulness of comprehensive approaches, and this approach can be readily adapted to management, monitoring and evaluation of other target ecosystems and biota.
- Bioaccumulation of 14C60 by the earthworm Eisenia fetidaDong Li
Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, United States
Environ Sci Technol 44:9170-5. 2010..b>Biota-sediment accumulation factors (BSAF) were measured after 24 h depuration in soils with high C(60) dosages (60, 100,..
- Modeling toxaphene behavior in the Great LakesXiaoyan Xia
Center for Air Resource Engineering and Science, Clarkson University, United States
Sci Total Environ 409:792-9. 2011..fate model, was used to calculate toxaphene concentrations in the atmosphere, water, soil, sediment, and biota. The performance of the model was evaluated by comparing calculated and reported concentrations in these ..
- Species delimitation and evolution in morphologically and chemically diverse communities of the lichen-forming genus Xanthoparmelia (Parmeliaceae, Ascomycota) in western North AmericaSteven D Leavitt
Department of Biology and the M L Bean Life Science Museum, 401 WIDB, Brigham Young University, Provo, Utah 84602, USA
Am J Bot 98:175-88. 2011Accurate species delimitation is important for understanding the diversification of biota and has critical implications for ecological and conservation studies...
- Effects of soil biota from different ranges on Robinia invasion: acquiring mutualists and escaping pathogensRagan M Callaway
Division of Biological Sciences, University of Montana, Missoula, Montana 59812, USA
Ecology 92:1027-35. 2011The net effects of soil biota on exotic invaders can be variable, in part, because net effects are produced by many interacting mutualists and antagonists...
- Estimation of ²¹⁰Po and ²¹⁰Pb and its dose to human beings due to consumption of marine species of Ennore Creek, South IndiaM Saiyad Musthafa
Post Graduate and Research Department of Zoology, The New College, Chennai, 600 014 Tamilnadu, India
Environ Monit Assess 184:6253-60. 2012A systemic study on the natural radionuclides such as (210)Po and (210)Pb in the environmental matrices and biota of Ennore Creek has been undertaken to establish a baseline data on the radiation profile of Ennore Creek environment...
- Does non-steroidal anti-inflammatory (NSAID) ibuprofen induce antioxidant stress and endocrine disruption in mussel Mytilus galloprovincialis?Maria Gonzalez-Rey
CIMA, Marine and Environmental Research Center, University of Algarve, Campus de Gambelas, 8000 135 Faro, Portugal
Environ Toxicol Pharmacol 33:361-71. 2012..Nevertheless, the information regarding IBU effects in biota is still sparse...
- Evolution of centralized nervous systems: two schools of evolutionary thoughtR Glenn Northcutt
Laboratory of Comparative Neurobiology, Scripps Institution of Oceanography and Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA
Proc Natl Acad Sci U S A 109:10626-33. 2012..Although the taxonomic affinities of the Ediacaran biota remain uncertain, a conservative interpretation suggests that a number of these taxa form clades that are closely ..
- Simultaneous determination of 2-naphthol and 1-hydroxypyrene in fish and shellfish contaminated with crude oil by gas chromatography-mass spectrometryHyun Hee Lim
Department of Environmental Science, Kongju National University, Kongju 314 701, Republic of Korea
Food Chem 138:791-6. 2013..The results showed that 2-NAP might be an important biomarker in biota contaminated with crude oil.
- Impact of historical mining assessed in soils by kinetic extraction and lead isotopic ratiosE Camizuli
UMR 6298, ARTéHIS, Université de Bourgogne CNRS Culture, 6 Bd Gabriel, Bat Gabriel, 21000 Dijon, France Electronic address
Sci Total Environ 472:425-36. 2014..if trace metals resulting from past mining and metallurgy persist in soils long after these activities have ceased, kinetic extractions suggest that metals, at least for these particular forest soils, do not represent a threat for biota.
- Deep water masses and sediments are main compartments for polychlorinated biphenyls in the Arctic OceanAnna Sobek
Department of Applied Environmental Science ITM and Bolin Centre for Climate Research, Stockholm University, 10691, Stockholm Sweden
Environ Sci Technol 48:6719-25. 2014There is a wealth of studies of polychlorinated biphenyls (PCB) in surface water and biota of the Arctic Ocean...
- Possible impacts of climate change on wetlands and its biota in the Brazilian AmazonD F Barros
Coordenação de Ciências da Terra e Ecologia, Museu Paraense Emilio Goeldi, Belem, PA, Brazil
Braz J Biol 74:810-20. 2014....
- GC-Content evolution in bacterial genomes: the biased gene conversion hypothesis expandsFlorent Lassalle
Universite de Lyon, Lyon, France Université Lyon 1, Villeurbanne, France CNRS, UMR 5558, Laboratoire de Biometrie et Biologie Evolutive, Villeurbanne, France CNRS, UMR 5557, Ecologie Microbienne, Villeurbanne, France INRA, USC 1364, Ecologie Microbienne, Villeurbanne, France Ecole Normale Supérieure de Lyon, Lyon, France
PLoS Genet 11:e1004941. 2015..to sexual Eukaryotes but also widespread among Bacteria and could therefore be an ancestral feature of cellular organisms. We argue that if gBGC occurs in bacteria, it can account for previously unexplained observations, such as ..
- Fukushima radionuclides in the NW Pacific, and assessment of doses for Japanese and world population from ingestion of seafoodPavel P Povinec
Department of Nuclear Physics and Biophysics, Comenius University, Bratislava, Slovakia
Sci Rep 5:9016. 2015Variations of Fukushima-derived radionuclides ((90)Sr, (134)Cs and (137)Cs) in seawater and biota offshore Fukushima and in the NW Pacific Ocean were investigated and radiation doses to the Japanese and world population from ingestion of ..
- Microplastics in coastal and marine environments of the western tropical and sub-tropical Atlantic OceanMonica F Costa
Laboratory of Ecology and Management of Estuarine and Costal Ecosystems LEGECE, Oceanography Department DOCEAN of the Federal University of Pernambuco UFPE, Av Arquitetura s n, Cidade Universitaria, Recife, Pernambuco CEP 50740 550, Brazil
Environ Sci Process Impacts 17:1868-79. 2015..The main environmental compartments (water, sediments and biota) are contaminated, but the consequences are still poorly understood...
- Speciation and Bioavailability Measurements of Environmental Plutonium Using Diffusion in Thin FilmsRuslan Cusnir
Institute of Radiation Physics, Lausanne University Hospital
J Vis Exp . 2015..since it is an alpha-particle emitter with long half-life which can potentially contribute to the exposure of biota and humans...
- Do pharmaceuticals bioaccumulate in marine molluscs and fish from a coastal lagoon?R Moreno-González
Instituto Español de Oceanografía, Centro Oceanográfico de Murcia, Apdo 22, c Varadero 1, 30740 San Pedro del Pinatar, Murcia, Spain
Environ Res 146:282-98. 2016..To the best of our knowledge, this is the first study that shows data about hydrochlorothiazide, levamisole and codeine in wild marine biota.
- Characterisation of the yeast and mould biota in traditional white pickled cheeses by culture-dependent and independent molecular techniquesHana Suranská
Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000, Ljubljana, Slovenia
Folia Microbiol (Praha) 61:455-463. 2016..The ITS-clone library approach provides the opportunity to analyse complex fungal communities associated with food products...
- Differential bioaccumulation of potentially toxic elements in benthic and pelagic food chains in Lake BaikalTomasz M Ciesielski
Department of Biology, Norwegian University of Science and Technology, Høgskoleringen 5, NO 7491, Trondheim, Norway
Environ Sci Pollut Res Int 23:15593-604. 2016..Concentrations of Cd, Hg, Pb and Se in Lake Baikal water and biota were low, while concentrations of As were similar or slightly higher compared to in other freshwater ecosystems...
- Arsenic and arsenic species in shellfish and finfish from the western Arabian Gulf and consumer health risk assessmentPeriyadan K Krishnakumar
Center for Environment and Water, Research Institute, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia Electronic address
Sci Total Environ 566:1235-44. 2016This study reports the levels of total arsenic and arsenic species in marine biota such as clams (Meretrix meretrix; N=21) and pearl oyster (Pinctada radiata; N=5) collected from nine costal sites in Jan 2014, and cuttlefish (Sepia ..
- Risk factors for fecal carriage of carbapenemase producing Enterobacteriaceae among intensive care unit patients from a tertiary care center in IndiaGajanand Mittal
Department of Microbiology, VMMC and Safdarjung Hospital, New Delhi, 110029, India
BMC Microbiol 16:138. 2016..resistant strains may spread to other host or transfer genetic resistance element to other members of micro-biota including pathogens...
- Microplastic pollution in Vembanad Lake, Kerala, India: The first report of microplastics in lake and estuarine sediments in IndiaS Sruthy
School of Environmental Sciences, Mahatma Gandhi University, Kottayam, Kerala 686560, India
Environ Pollut . 2016..The impact of microplastics pollution on the environment and biota is not well known...
- Monitoring transfer of recombinant and nonrecombinant plasmids between Lactococcus lactis strains and members of the human gastrointestinal microbiota in vivo--impact of donor cell number and dietK Tuohy
TNO BIBRA International Ltd, Carshalton, Surrey, UK
J Appl Microbiol 93:954-64. 2002..to the purported risks of DNA transfer from food-borne genetically modified microorganisms (GMMOs) using the human biota associated (HBA) rat model...
- Precipitation pulses and carbon fluxes in semiarid and arid ecosystemsTravis E Huxman
Ecology and Evolutionary Biology, University of Arizona, Tucson 85721 0088, USA
Oecologia 141:254-68. 2004..pulse size regulates C balance by determining the temporal duration of activity for different components of the biota. Microbial respiration responds to very small events, but the relationship between pulse size and duration of ..
- Impact of low doses of tritium on the marine mussel, Mytilus edulis: genotoxic effects and tissue-specific bioconcentrationAwadhesh N Jha
School of Biological Sciences, University of Plymouth, Plymouth PL4 8AA, UK
Mutat Res 586:47-57. 2005..The study also suggests that the generic dose limits recommended by the International Atomic Energy Agency for the protection of aquatic biota might not be applicable to all aquatic organisms.
- Small RNAs in flower developmentHeike Wollmann
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Eur J Cell Biol 89:250-7. 2010Development of multi-cellular organisms depends on the correct spatial and temporal expression of numerous genes acting in concert to form regulatory networks. The expression of individual genes can be controlled at different levels, e.g...
- James A Imlay; Fiscal Year: 2015..Their toxicity is underscored by the distribution throughout the biota of dedicated detoxification systems that bind and export them...
- Gut micro biota in patients with multiple sclerosisHoward L Weiner; Fiscal Year: 2012..It applies for the first time an important newly developing technology to gain potential basic insights into an autoimmune disease whose underlying pathogenesis remains unknown. ..
- Erin C Steinbach; Fiscal Year: 2014..We will monitor germ-free p110delta[D910A/D910A] mice and those re-colonized with enteric micro biota for the development of colitis...
- Defensin gene copy number and mucosal innate immunityJAY V contact SOLNICK; Fiscal Year: 2010..Aim 2 we will identify three groups of macaques with low, intermediate, or high BD2 GNC, and compare their gastric biota and response to experimental challenge with H. pylori. Since only about 5 to 10% of humans infected with H...
- CHRONOBIOLOGIC MARKERS FOR LAB MEDICINE AND THERAPYFranz Halberg; Fiscal Year: 2012..implementation of such monitoring worldwide via BIOCOS (the study of effects of the BlOsphere and the COSmos on biota), and thereby the mapping of about-weekly, half-weekly (circaseptan and circasemiseptan) and other components in ..
- Zhiheng Pei; Fiscal Year: 2014..In a small scale study, we also found that 3 of 3 cases of EA harbored the type II biota. The findings have opened a new approach to understanding the recent surge in the incidence of EA...
- Adaptive evolution of pathogenesis towards symbiosisSerap Aksoy; Fiscal Year: 2009..microbial relations are extremely pervasive, with examples being found among all levels of the earth's biota. These associations vary with regard to their interactive nature, and are characterized by the benefit (or ..
- The Role of Novel Bacteria in Male UrethritisLisa E Manhart; Fiscal Year: 2012..we propose to use broad range 16S rRNA gene PCR with pyrosequencing to describe and compare the urethral bacterial biota in 136 men with idiopathic urethritis to that in 136 men without urethritis...
- Metagenomic study of the human skin microbiome associated with acneHuiying Li; Fiscal Year: 2010..our analysis of the microbiome of the pilosebaceous units will shed light on the microbial composition of the skin biota and its relation to acne...
- WOLFGANG KLAUS VOGELBEIN; Fiscal Year: 2014..Because measuring contaminant uptake in biota is time consuming and expensive, models have been developed to predict contaminant fate and disposition...
- Development of Novel Inhibitors of Clostridium difficile.Jane Ryan; Fiscal Year: 2013..b>Biota's novel FtsZ inhibitor compounds possess potency against C...
- Foregut microbiome in development of esophageal adenocarcinomaZhiheng Pei; Fiscal Year: 2009..In a small-scale study, we also found that 3 of 3 cases of EA harbored the type II biota. The findings have opened a new approach to understanding the recent surge in the incidence of EA...
- DANIEL CHAMPLIN PROPHETER; Fiscal Year: 2014..Furthermore, these studies will likely contribute to our understanding of how innate immunity contributes to maintaining a healthy and symbiotic intestinal micro biota.
- BACTERIAL METAL DETOXIFICATION--EXTRACELLULAR CHELATORSAndrew Gordon; Fiscal Year: 1991..improved understanding of the response of aquatic environments to heavy metal contamination, influence of aquatic biota in "buffering" toxicity of heavy metals, and the influence of metals on lower members of the human food chain...
- Potential Drugs from Poorly Understood Costa Rican BiotaJon Clardy; Fiscal Year: 2004..The separation technology will be assess both through analysis of HTS screening data and benchmarking the efficiency of purifying compounds from key fractions. ..
- Innovative Influenza Therapeutic and Prophylactic for Biodefense ApplicationsJane Ryan; Fiscal Year: 2009..b>Biota Holdings Ltd developed FLUNET as a second generation NAI, following the launch of Relenza, the first in class NAI, ..
- Novel Influenza Biodefense Therapeutic and ProphylacticJane Ryan; Fiscal Year: 2004..b>Biota Holdings Ltd developed the first-in-class NAI drug, Relenza (tm), through a partnership with GlaxoSmithKline (GSK)...
- ORAL BIOFILMS: DIFFERENTIAL DISPLAY AND GENETIC EXCHANGEMichael Gilmore; Fiscal Year: 2003Adult periodontitis is a biota shift disease caused by an ecological transition of the dental plaque, and consequent chronic inflammation...
- PCB Congener/Metabolite Patterns in Akwesasne MohawksAnthony DeCaprio; Fiscal Year: 2006..determinants of polychlorinated biphenyl (PCB) body burden, including those related to consumption of contaminated biota, in the Akwesasne Mohawks and in other exposed populations...
- CONFERENCES ON THE SAFETY EVALUATION OF CHEMICALSBernard Goldstein; Fiscal Year: 1992..from among these four candidates: Methods for the Assessment of Risk of Hazardous Wastes to Human and Non-Human Biota; Methods for the Assessment of the Effects of Chemicals on Ecosystems; Non- Vertebrate Substitutes for Mammalian ..
- MicroArrays in Grass Shrimp and Sheepshead MinnowsPatrick Larkin; Fiscal Year: 2005..Measurement and analysis of contaminants in the environment and evaluation of their effects on biota is very important to the EPA in its Superfund monitoring activities Grass shrimp and sheepshead minnows are two ..
- Probing functions of NAM and NAD+ salvage in development and aging in C. elegansWendy Hanna-Rose; Fiscal Year: 2013..if there is an evolutionarily conserved extracellular function for an NAD+ biosynthetic enzyme in multi-cellular organisms. This work will help elucidate the molecular mechanisms underlying organ pathologies caused by perturbations ..
- Suppression of Clostridium difficile by CommensalsKenneth Wilson; Fiscal Year: 2004..difficile population size (quantitative cultures) and for determination of the composition of fecal biota. Ribosomal DNA in these specimens will be amplified with PCR, then studied by using 1) high throughput sequencing ..
- TLR4 Inhibition to Reduce Cerebral Ischemia Reperfusion InjuryLORI ANN HOLLE; Fiscal Year: 2011..This very complex system evolved over 700 million years to protect uni- and multi- cellular organisms from infection with bacteria, fungi, viruses and other pathogens...
- BIOACTIVE NATURAL PRODUCTS FROM MARINE EXTREMOPHILESRamesh Pandey; Fiscal Year: 2000..Our collaborative search for antimicrobial, antifungal, antiviral and immunomodu1atory activity in this unique biota may provide many new classes of compounds that have no counterparts in terrestrial plants or animals...
- Friedhelm Hildebrandt; Fiscal Year: 2016..PC are utilized across evolution, from single cellular organisms to humans, for cellular sensory tasks, including photo-, mechano-, thermo-, olfactory, and hormonal ..
- Genetic Control of Axial Patterning in Drosophila EyeAmit Singh; Fiscal Year: 2010..PUBLIC HEALTH RELEVANCE: Axial patterning, a fundamental process of organogenesis in multi-cellular organisms, involves transition of a mono-layered epithelium to a three- dimensional organ...
- Control of developmental timing and body size in DrosophilaMICHAEL BRENDAN O'CONNOR; Fiscal Year: 2013DESCRIPTION (provided by applicant): Proper development of all multi-cellular organisms requires not only correct spatial control of cellular interactions, but also correct timing of specific gene expression programs during development...
- Danny Reinberg; Fiscal Year: 2014DESCRIPTION (provided by applicant): The complexity of multi-cellular organisms characterized by cell specialization and sophisticated tissue and organ architecture is possible because of an efficient indexing system that keeps track of ..
- R Dyche Mullins; Fiscal Year: 2015..organisms use 'amoeboid'or 'crawling'motility to find and engulf food while multi-cellular organisms rely on this type of migration for many processes including: embryonic development, remodeling of the ..
- JOHN PETER GERGEN; Fiscal Year: 2014..provided by applicant): The regulation of gene transcription is critical for the development of multi-cellular organisms and aberrations in transcriptional regulation are frequently associated with disease...
- Interaction between B. cereus RecQ helicase and topoisomerase IIIZhiyu Li; Fiscal Year: 2010..Unlike many single cellular organisms, such as Escherichia coli, Saccharomyces cerevisiae, and Saccharomyces pombe, which possess one or two type ..
- David H Price; Fiscal Year: 2016..control plays a major role in regulating transcription throughout development and differentiation of multi-cellular organisms. The process is characterized by the default action of negative elongation factors, including NELF and DSIF ..
- Katsuhiko Murakami; Fiscal Year: 2016..PUBLIC HEALTH RELEVANCE: Gene expression is fundamental to all cellular organisms and is critical for understanding cell development, maintenance, and disease...
- Ian F Smith; Fiscal Year: 2016..applicant): Intercellular communication is an absolute requirement for the coordinated functioning of multi-cellular organisms, and cells have long been known to employ gap junctions and synapses to communicate with their neighbors...
- Natalie A Cookson; Fiscal Year: 2015..spans of individual cells, such as neurons and stem cells, influence the rate and grace with which multi-cellular organisms age...
- Structural Studies of Bacterial Transcription InitiationBrian Bae; Fiscal Year: 2013..by the catalytic core of the DNA dependent RNA polymerase (RNAP), which is highly conserved among all cellular organisms. In bacteria, the core RNAP interacts with the sigma factor to form the holoenzyme that specifically binds ..
- Cross regulation between JNK and Insulin SignalingDirk Bohmann; Fiscal Year: 2010..on Foxo, a transcription factor that has been shown to promote the stress resistance and longevity of multi cellular organisms. This proposal describes experiments that will test the hypothesis that JNK signaling activates Foxo to ..
- MATTHEW PHILLIP TORRES; Fiscal Year: 2015..of extracellular signals into intracellular responses and therefore critical for the survival of multi-cellular organisms. Most neurotransmitters and hormones bind to cell surface receptors and activate G proteins that elicit ..
- MEMBRANE TRAFFICKING IN MAMMALIAN CELLSWilliam Brown; Fiscal Year: 2009..Secretion and endocytosis play fundamental biological roles at the levels of both single cells and multi-cellular organisms to control a wide array of physiological processes including nutrient uptake, secretion of hormones and ..
- Molecular Mechanisms of Impaired DAN Damage Response in Leukemia PathogenesisJames J D Hsieh; Fiscal Year: 2012..Although basic framework of the S-phase checkpoint in multi-cellular organisms has been outlined, the mechanistic details remain to be elucidated...
- James J Hsieh; Fiscal Year: 2015..Although basic framework of the S-phase checkpoint in multi-cellular organisms has been outlined, the mechanistic details remain to be elucidated...
- Juris A Grasis; Fiscal Year: 2015..PUBLIC HEALTH RELEVANCE: Viruses are the most abundant entities on Earth and all cellular organisms have mechanisms built to recognize them. However, not all viruses cause Human pathogenesis...
- Genetic Control of Non-Autonomous Survival in DrosophilaAndreas Bergmann; Fiscal Year: 2011..However, the complexity of multi-cellular organisms has made it difficult to obtain a comprehensive understanding of all extracellular signaling mechanisms ..
- Kevin M Weeks; Fiscal Year: 2016..for information transfer in biology - in simple replicating entities like RNA viruses and in complex multi-cellular organisms. RNA is uniquely able to play this role because it encodes information at two levels: in its linear primary ..
- William J Brown; Fiscal Year: 2016..Secretion plays fundamental biological roles at the level of both single cells and multi-cellular organisms t control a wide array of physiological processes including release of hormones and digestive enzymes, ..
- MOLECULAR DYNAMICS IN CELLULAR AGING: A SYNTHETIC BIOLOGY APPROACH.CLIFFORD LEE WANG; Fiscal Year: 2012..As the number of senescent cells or apoptotic incidents accumulates, multi-cellular organisms are thought to develop phenotypes associated with aging...
- Proteomic and Biochemical Studies of Bax Regulatory Proteins in ApoptosisYuchun Du; Fiscal Year: 2010..or programmed cell death) plays critical roles in normal development and tissue homeostasis in multi-cellular organisms. Impaired apoptosis is both critical in the development of a variety of human diseases and a major barrier ..
- Brian D Strahl; Fiscal Year: 2016..beyond the DNA sequence that is needed to regulate the genome and allow the proper development of multi-cellular organisms. Posttranslational modifications (PTMs) of histones modulate the organization of chromatin for replication, ..
- Epigenomic Analysis of Facioscapulohumeral Muscular DystrophyKyoko Yokomori; Fiscal Year: 2013..by applicant): Epigenetic regulatory processes are critical for the normal development and function of multi-cellular organisms and play an important role in human disease...
- Symbiosis and Immunity in the Tsetse FlyBrian L Weiss; Fiscal Year: 2013..Insects represent a group of advanced multi-cellular organisms that harbor well- documented symbiotic associations. One such insect, the tsetse fly (Glossina spp...
- Wnt signalingDianqing Wu; Fiscal Year: 2013..PUBLIC HEALTH RELEVANCE: Cell-cell communication is essential for normal functions of multi-cellular organisms including human...
- Understanding Gene Transcription from First-Principles: A single-molecule studyAlexandros Pertsinidis; Fiscal Year: 2012..applicant) Abstract: The accurate regulation of gene expression is crucial for proper development of multi-cellular organisms and for maintaining cell homeostasis in adult tissues...
- MARINA LYN ELLEFSON CROWDER; Fiscal Year: 2015..In multi-cellular organisms, the microtubule-based bipolar spindle is a large complex cellular machine responsible for correctly ..
- Targeting Notch3 in Lung CancerThao P Dang; Fiscal Year: 2012Genes that are crucial in the normal development of multi-cellular organisms often play a role in oncogenesis when aberrantly expressed in adult tissues...
- Mechanisms of Bax ActivationXu Luo; Fiscal Year: 2010..cell death, is a biochemical pathway critical to normal development and tissue homeostasis in multi-cellular organisms. Aberrant suppression of apoptosis is a requisite contributor to human cancer...
- Jon M Kaguni; Fiscal Year: 2014DESCRIPTION (provided by applicant): All cellular organisms rely on a multi-protein molecular machine named the replisome to duplicate their genomes...
- The function and regulation of the cullin family E3 ubiquitin ligasesZhen Qiang Pan; Fiscal Year: 2012..and cell biology methods will be employed to explore the novel function by IRS-1 in inducing permanent cell arrest (senescence), which has emerged as a prominent anti-cancer mechanism in multi- cellular organisms including humans.
- Precision Multi-site Cellular Dosing using a Membrane-Based Laminar-Flow DeviceRobyn Goforth; Fiscal Year: 2010..Public Health Relevance: A fundamental component of cellular organisms is the ability of cells to sense and respond to their environment...
- Molecular Genetics of Stem Cell in DrosophilaKrishna Moorthi Bhat; Fiscal Year: 2011..These studies will help understand pathways that govern the self-renewing and terminal asymmetric division of precursor cells in multi-cellular organisms.
- Cell adhesion mediated self-recognitionSoichiro Yamada; Fiscal Year: 2013..RELEVANCE: Regulation of cell-cell adhesion plays critical roles in development and homeostasis of multi-cellular organisms. The goal of this proposal is to analyze how individual epithelial cells recognize neighboring cells to form ..
- Biological roles of Insulin Degrading EnzymeJoogyung Hyun; Fiscal Year: 2009..DESCRIPTION (provided by applicant): Insulin signaling is an evolutionarily conserved mechanism used by multi-cellular organisms to regulate metabolism, growth, and lifespan...
- REGULATION OF ACTIN FILAMENT ASSEMBLIES BY COFILIN/ADFAmy McGough; Fiscal Year: 2003..test the hypothesis that cofilin's effects on actin filament structure are central to its function in multi-cellular organisms. Our fourth goal is to explore the hypothesis that cofilin promotes the formation of alternative actin ..
- SYMPOSIUM ON ORGANISMS WITH SLOW AGINGCaleb Finch; Fiscal Year: 2000..SOSA will critically examine the emerging evidence that some multi-cellular organisms have evolved very slow rates of aging with anti-aging mechanisms that are pertinent to human aging processes...