A meta-analysis of incision and curettage versus steroid injection for the treatment of chalazia
ARP Aycinena1 #, A Achiron1, M Paul1, 2, Z Burgansky-Eliash1, 2
1 Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. 2 Department of Ophthalmology, The Edith Wolfson Medical Center, Holon, Israel
# : presenting author
Cite as
Research abs 2015;2:1380
Sackler Symposium 2015
New York State/American Program, Sackler Faculty of Medicine Tel Aviv University, Israel

To compare the efficacy of the chalazia treatment modalities of incision and curettage (I&C) and intralesional steroid injections (SI).

Clinical relevance

Chalazia are the most common eyelid lesions seen in ophthalmological practice. They are often cosmetically disfiguring and may also cause ptosis and visual disturbances. Despite studies comparing chalazion treatment by either I&C or SI, controversy remains. This uncertainty prompted us to attempt to determine the best approach to chalazion treatment for our patients.


Full publications of randomized controlled trials that compared I&C to SI were identified. Aggregated success rate, weighted summary proportions and weighted pooled relative risk (RR) for success was calculated for each method.


Data was extracted from eight publications that met our criteria, between 1984 and 2013. There were 264 patients treated by I&C with a larger aggregate success rate of 78.0% with one procedure and 86.7% with one or two procedures (p<0.05 for both comparisons). There were 288 patients treated by SI with aggregate success rate of 60.4% with one injection and 72.5% with one or two injections. Compared to I&C, the overall RR for SI with one procedure was 0.77 (p = 0.05) while the overall RR for one or two procedures was 0.89 (p = 0.002).


Our analysis shows that I&C is more effective than SI with one procedure. This benefit is reduced when comparing one or two attempts of I&C and SI. Studies failed to show difference in the incidence of complications with either procedure.

ISSN : 2334-1009