Quantitative Imaging with High Frequency Ultrasound

Summary

Principal Investigator:
Abstract: [unreadable] DESCRIPTION (provided by applicant): The long-term objective of this research is the development of an integrated high frequency ultrasound (HFUS) transducer system for quantitative imaging of skin and subcutaneous tissues for detection and characterization of abnormalities, e.g. skin tumors. If successful, the integrated system could provide a blueprint for image-guided surgery of skin tumors using high intensity focused ultrasound (HIFU), where quantitative imaging of the viscoelastic properties will provide robust means of guidance, monitoring and assessment of the surgery. [unreadable] [unreadable] [unreadable]
Funding Period: 2007-03-01 - 2010-02-28
more information: NIH RePORT

Top Publications

  1. pmc Viscoelastic property measurement in thin tissue constructs using ultrasound
    Dalong Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA
    IEEE Trans Ultrason Ferroelectr Freq Control 55:368-83. 2008
  2. pmc A post-beamforming 2-D pseudoinverse filter for coarsely sampled ultrasound arrays
    Yayun Wan
    Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis St Paul, MN, USA
    IEEE Trans Ultrason Ferroelectr Freq Control 56:1888-902. 2009
  3. ncbi Monitoring and guidance of minimally-invasive thermal therapy using diagnostic ultrasound
    Emad S Ebbini
    Department of Electrical and Computer Engineering, University of Minnesota, Twin Cities, MN, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4283, 4285-6. 2009
  4. ncbi A 2D post-beamforming filter for contrast restoration in medical ultrasound: in vivo results
    Yayun Wan
    Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:1945-8. 2009
  5. ncbi Real-time two-dimensional temperature imaging using ultrasound
    Dalong Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:1971-4. 2009

Detail Information

Publications5

  1. pmc Viscoelastic property measurement in thin tissue constructs using ultrasound
    Dalong Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA
    IEEE Trans Ultrason Ferroelectr Freq Control 55:368-83. 2008
    ..These findings were confirmed by comparing the magnitude response of the FHO (with parameters obtained using the EKF) with the measured ones for different thin tissue constructs...
  2. pmc A post-beamforming 2-D pseudoinverse filter for coarsely sampled ultrasound arrays
    Yayun Wan
    Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis St Paul, MN, USA
    IEEE Trans Ultrason Ferroelectr Freq Control 56:1888-902. 2009
    ..The results are supported by image reconstructions from a simulated cyst phantom obtained using finely and coarsely sampled apertures with and without the application of the regularized 2-D PIO...
  3. ncbi Monitoring and guidance of minimally-invasive thermal therapy using diagnostic ultrasound
    Emad S Ebbini
    Department of Electrical and Computer Engineering, University of Minnesota, Twin Cities, MN, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4283, 4285-6. 2009
    ..With the advent of highperformance computing hardware, these imaging modes are now implementable in real-time. This will lead to active realtime monitoring and control of a range of thermal therapies in the very near future...
  4. ncbi A 2D post-beamforming filter for contrast restoration in medical ultrasound: in vivo results
    Yayun Wan
    Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:1945-8. 2009
    ..The 2D PIO's ability to remove the clutter from grating lobe is expected to improve the performance of speckle tracking algorithms for the estimation of tissue and blood displacements in vivo...
  5. ncbi Real-time two-dimensional temperature imaging using ultrasound
    Dalong Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:1971-4. 2009
    ..Currently we have verified our system with elastography tissue mimicking phantom and in vitro porcine heart tissue, excellent repeatability and sensitivity were demonstrated...