2013 Eye Movements: The Motor System that Sees the World GRC &GRS

Summary

Principal Investigator: Michele A Basso
Abstract: DESCRIPTION (provided by applicant): The oculomotor system is arguably the best understood motor control system. Traditionally, oculomotor scientists studied each eye movement subsystem in isolation. Only recently have scientists turned their attention to more complex problems such as the neuronal control of combined vergence and saccadic eye movements or the neuronal control of combined saccadic and smooth pursuit eye movements. Advances in these areas are opening up new topics of inquiry to the field of oculomotor neuroscience such as target selection - how does the brain select a single visual stimulus to guide eye movements? Is the process of selection the same for different eye movement subsystems or is it a shared mechanism? Do binocular disparity signals provide a low-level target selection mechanism for saccades or pursuit? Questions such as these are generating much excitement in the field and are producing results that have implications for the fields of visual neuroscience, cognitive neuroscience and computational neuroscience. As such, our goal in this application is to provide the oculomotor science community a forum to present and hear about cutting-edge research and to interact in an intimate, informal yet scientifically rigorous setting. In 2005, we held the first oculomotor Gordon Research Conference (GRC) ever, titled Oculomotor System Biology. The success of the first meeting resulted in second, sponsored GRC in 2007. The third and so far, most successful oculomotor GRC occurred in 2011, titled Eye Movements: The Motor System that Sees the World. The topics included: Eye Movements as a Probe for Attention, Perception, and Decision Making Mechanisms, in which the speaker's explored how the oculomotor system is used as a read-out for perceptual decision-making;The Action between Eye Movements, which explored the characteristics and control mechanisms for microsaccades and Central and Peripheral Oculomotor Subsystems in Health and Disease, which evaluated new findings about the role of peripheral mechanisms in controlling eye orientation. In the meeting scheduled for 2013 we hope to capitalize on the excitement generated from the 2011 meeting and plan to explore topics such as: Rodent Models for Higher Order Oculomotor Control;In this session the recent surge in the use of small mammals that are easily manipulated genetically to explore cognition and eye movements will be the theme. Beyond Black Boxes - New Computational Approaches for Understanding Oculomotor Control;in this session the topic of applying mathematical models to the oculomotor system such as Bayesian inference will be explored. More than Pretty Pictures- Lessons Learned from Imaging the Oculomotor System;in this session, we will explore how the technique of fMRI and other imaging methods enhances our understanding of the neural circuits underlying eye movements. This proposal requests support for a conference whose objective is to bring together scientists and physicians to discuss recent work in the oculomotor system. We plan to bring together early-career and established investigators to propel forward novel research venues and collaborations.
Funding Period: 2013-03-01 - 2014-02-28
more information: NIH RePORT

Research Grants

  1. Center for Biomedical Research Excellence in Pathogen-Host Interactions
    Stephen B Pruett; Fiscal Year: 2013
  2. Defining and Treating Written Language Disabilities
    VIRGINIA WISE BERNINGER; Fiscal Year: 2013
  3. Neural and Behavioral Interactions Between Attention, Perception, and Learning
    NICHOLAS BENJAMIN TURK-BROWNE; Fiscal Year: 2013
  4. Center for Novel Therapeutics for HIV-Associated Cognitive Disorders
    Justin C McArthur; Fiscal Year: 2013
  5. MECHANISMS AND COFACTORS OF HIV TRANSMISSION TO WOMEN
    Julie M Overbaugh; Fiscal Year: 2013
  6. Core Support for Vision Research
    Michael E Goldberg; Fiscal Year: 2013
  7. NEURAL CONTROL OF VISUAL-VESTIBULAR BEHAVIOR
    Michael J Mustari; Fiscal Year: 2013
  8. Jules Stein Eye Institute Core Grant for Vision Research
    Wayne L Hubbell; Fiscal Year: 2013
  9. Multimodal Imaging of Spatiotemporal Integration in the Human Visual System
    Jonathan A Winawer; Fiscal Year: 2013
  10. Mechanisms of Visual Perception
    MICHAEL NEIL SHADLEN; Fiscal Year: 2013

Detail Information

Research Grants30

  1. Center for Biomedical Research Excellence in Pathogen-Host Interactions
    Stephen B Pruett; Fiscal Year: 2013
    ..We expect the combined reductionist and global approach in this COBRE to produce significant progress in research on these pathogens. ..
  2. Defining and Treating Written Language Disabilities
    VIRGINIA WISE BERNINGER; Fiscal Year: 2013
    ..The proposed multidisciplinary research has practical significance for improving diagnosis and providing more effective services which may lower such risks. ..
  3. Neural and Behavioral Interactions Between Attention, Perception, and Learning
    NICHOLAS BENJAMIN TURK-BROWNE; Fiscal Year: 2013
    ..These advances will shed light on the plasticity that occurs during development and during the recovery and rehabilitation of visual function following eye disease, injury, or brain damage. ..
  4. Center for Novel Therapeutics for HIV-Associated Cognitive Disorders
    Justin C McArthur; Fiscal Year: 2013
    ..5. To identify and validate surrogate biomarkers based on proteomics and lipomics. ..
  5. MECHANISMS AND COFACTORS OF HIV TRANSMISSION TO WOMEN
    Julie M Overbaugh; Fiscal Year: 2013
    ..We expect that each of these projects will draw on the expertise of others in the team, and in some cases, will include parallel studies that address synergistic biological questions in the same populations. ..
  6. Core Support for Vision Research
    Michael E Goldberg; Fiscal Year: 2013
    ..This core will also facilitate collaboration among members of the Columbia vision research community, and encourage scientists not currently engaged in vision research to use their expertise to solve problems related to vision. ..
  7. NEURAL CONTROL OF VISUAL-VESTIBULAR BEHAVIOR
    Michael J Mustari; Fiscal Year: 2013
    ..Therefore, our studies are designed to test real SP circuits in a manner that will aid in the diagnosis and potential treatment of disorders associated with strabismus, neurodegenerative disease, brain injury and stroke. ..
  8. Jules Stein Eye Institute Core Grant for Vision Research
    Wayne L Hubbell; Fiscal Year: 2013
    ..Support in the form of the Core grant is requested to maintain these Modules through instrument service contracts, and to provide necessary personnel support to assist and train users and provide routine maintenance. ..
  9. Multimodal Imaging of Spatiotemporal Integration in the Human Visual System
    Jonathan A Winawer; Fiscal Year: 2013
    ..The candidate will seek an independent faculty position during the second year of the mentored phase. ..
  10. Mechanisms of Visual Perception
    MICHAEL NEIL SHADLEN; Fiscal Year: 2013
    ..Moreover, by advancing optogenetic methods in the macaque, the proposed research will facilitate the study of sophisticated neural mechanisms at a more refined level than was hitherto possible. ..
  11. Disparity Processing in Human Visual Cortex
    Anthony M Norcia; Fiscal Year: 2013
    ....
  12. Continuously Decoding Visual Perception and Working Memory
    Michael S Pratte; Fiscal Year: 2013
    ..abstract_text> ..
  13. FASEB SRC Retinal Neurobiology &Visual Processing
    Maureen A McCall; Fiscal Year: 2013
    ..abstract_text> ..
  14. Plasticity at the Excitatory Synapse
    Richard L Huganir; Fiscal Year: 2013
    ..Understanding these basic mechanisms of synaptic transmission and plasticity will provide insight into normal and abnormal brain function. ..
  15. CORE GRANT FOR VISION RESEARCH
    J Anthony Movshon; Fiscal Year: 2013
    ....
  16. Neural pathways and behavioral state in the mouse visual system
    CRISTOPHER NIELL; Fiscal Year: 2013
    ..This work will advance our understanding of the selective gating of information in the brain, which is essential for both visual function and cognitive processes. ..