A RANDOMIZED CONTROLLED TRIAL OF ECHINACEA IN CHILDREN

Summary

Principal Investigator: James Taylor
Abstract: Upper respiratory tract infections (URI's) are a significant health burden in childhood. URI's are a major reason for visits to health care providers, and up to 35% of young children at any given time are taking some over-the-counter cold medication. Unfortunately, data suggest that most of these medications have limited effectiveness. Alternative medical therapies are growing in popularity; in a recent survey of parents of children being seen by pediatricians in Seattle, Washington, 24.2% indicated that their child had been seen by an alternative medicine health care provider, and 53.3% therapies for the treatment of URI's in children. The proposed study is a randomized, double blind, placebo controlled trial of echinacea for the treatment of URI's in children 2-11 years old. The aims of the project are: to determine if echinacea shortens the duration and/or lessens the severity of URI's, if children receiving echinacea for treatment of URI's have a reduced rate of secondary bacterial infections, and to determine if the use of echinacea in patients 2-11 years old is associated with any significant side effects. A two-year study of 600 children is planned. Not only will the results of this study will determine if echinacea, the most popular medicinal herb sold in the United States, is an effective therapy for URI's in children, the study will provide a design framework for future assessments on the efficacy of other complementary and alternative medicines in children.
Funding Period: 2000-04-01 - 2003-03-31
more information: NIH RePORT

Top Publications

  1. ncbi Echinacea purpurea for prevention of upper respiratory tract infections in children
    Wendy Weber
    Naturopathic Medicine Department, Bastyr University, Kenmore, WA 98028 4966, USA
    J Altern Complement Med 11:1021-6. 2005
  2. pmc Traditional Chinese herbal remedies for asthma and food allergy
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Allergy Clin Immunol 120:25-31. 2007
  3. pmc Efficacy and mechanisms of action of traditional Chinese medicines for treating asthma and allergy
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA
    J Allergy Clin Immunol 123:297-306; quiz 307-8. 2009
  4. pmc Complementary and alternative medicine in pediatric allergic disorders
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, New York, USA
    Curr Opin Allergy Clin Immunol 9:161-7. 2009

Scientific Experts

Detail Information

Publications4

  1. ncbi Echinacea purpurea for prevention of upper respiratory tract infections in children
    Wendy Weber
    Naturopathic Medicine Department, Bastyr University, Kenmore, WA 98028 4966, USA
    J Altern Complement Med 11:1021-6. 2005
    ..The aim of this study was to determine whether Echinacea purpurea given to children for the treatment of acute upper respiratory tract infection (URI) was effective in reducing the risk of subsequent URI...
  2. pmc Traditional Chinese herbal remedies for asthma and food allergy
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Allergy Clin Immunol 120:25-31. 2007
    ..This effort may lead to improved therapies and better health care/patient outcomes. This review presents an update on the most promising Chinese herbal remedies for asthma and food allergy...
  3. pmc Efficacy and mechanisms of action of traditional Chinese medicines for treating asthma and allergy
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA
    J Allergy Clin Immunol 123:297-306; quiz 307-8. 2009
    ..There is increasing scientific evidence supporting the use of TCM for asthma treatment...
  4. pmc Complementary and alternative medicine in pediatric allergic disorders
    Xiu Min Li
    Department of Pediatrics, Mount Sinai School of Medicine, New York, New York, USA
    Curr Opin Allergy Clin Immunol 9:161-7. 2009
    ..This review focuses on traditional Chinese medicine (TCM) herbal products and acupuncture for treating pediatric allergies...