vent

Summary

Gene Symbol: vent
Description: ventral expressed homeobox
Alias: vega2, vent1, wu:fe36b11, homeobox protein VENTX
Species: zebrafish

Top Publications

  1. ncbi Functional interaction of vega2 and goosecoid homeobox genes in zebrafish
    A Kawahara
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genesis 28:58-67. 2000
  2. doi Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization
    Birgit Kagermeier-Schenk
    Biotechnology Center and Center for Regenerative Therapies, Technische Universitat Dresden, Tatzberg 47, 01307 Dresden, Germany
    Dev Cell 21:1129-43. 2011
  3. doi A direct role for Wnt8 in ventrolateral mesoderm patterning
    Kevin D Baker
    Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
    Dev Dyn 239:2828-36. 2010
  4. pmc Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like
    Hyunju Ro
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 2425, USA
    Nat Cell Biol 11:1121-7. 2009
  5. doi Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish
    Maria Vega C Flores
    Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
    Nat Cell Biol 10:346-52. 2008
  6. ncbi WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation
    Marie Christine Ramel
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Dev Biol 287:237-48. 2005
  7. ncbi Repression of the vertebrate organizer by Wnt8 is mediated by Vent and Vox
    Marie Christine Ramel
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Development 131:3991-4000. 2004
  8. ncbi Patterning the early zebrafish by the opposing actions of bozozok and vox/vent
    A E Melby
    Department of Biochemistry and Center for Developmental Biology, University of Washington, Seattle 98195 7350, USA
    Dev Biol 224:275-85. 2000
  9. ncbi A role for MKP3 in axial patterning of the zebrafish embryo
    Michael Tsang
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Development 131:2769-79. 2004
  10. ncbi A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organizer formation in zebrafish
    Takashi Shimizu
    Department of Molecular Oncology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Mech Dev 118:125-38. 2002

Scientific Experts

  • Z Kozmik
  • Stefan Hans
  • Shunji Jia
  • Marie Christine Ramel
  • Dan Li
  • Huaqin Sun
  • Kevin D Baker
  • Shi Wei
  • Anna Voronina
  • Wei Shi
  • Igor B Dawid
  • Roberto Moreno-Ayala
  • Arne C Lekven
  • Teddy Young
  • Xiaozhi Rong
  • Ying He
  • Lei Feng
  • Karuna Sampath
  • Jue Zhao
  • Zhongde Ye
  • Maximilian Schuff
  • Shimin Lim
  • Shu Yu Wu
  • Jian Meng Cao
  • Birgit Kagermeier-Schenk
  • Iryna Kozmikova
  • Xun Wei Xie
  • Hai Bin Zhao
  • Heinz Georg Belting
  • Jamie L Seebald
  • Wenqian Deng
  • Yongxin Ma
  • Dachang Tao
  • Melanie Philipp
  • Anming Meng
  • Michael J Jurynec
  • Saijun Mo
  • Minyong Chen
  • Hyunju Ro
  • Frederic M Rosa
  • Norihito Kishimoto
  • Sung Kook Hong
  • Maria Vega C Flores
  • Máté Varga
  • Xueying Lin
  • A E Melby
  • Shingo Maegawa
  • Ujwal J Pyati
  • Claudio N Gilardelli
  • Michael Tsang
  • Jared W Ragland
  • Yao Yao
  • Elena Pshennikova
  • Ming Gao
  • Hanqiao Shang
  • Samuel Sidi
  • Xueran Chen
  • Kun He
  • Yang Yang
  • Qiang Wang
  • Zhaoxia Du
  • Chen Wang
  • Yu Cao
  • Fen Wang
  • Aijun Hao
  • Denhi Schnabel
  • Enrique Salas-Vidal
  • Hilda Lomeli
  • Cunming Duan
  • Peter Wehner
  • Ling Lu
  • Chen Chen
  • Yun Li
  • Jianfeng Zhou
  • Siew Tein Wang
  • Lei Sun
  • Ee Kim Tan
  • Xiaofeng Xu
  • Yogavalli Poobalan
  • Peng Wu
  • Hao Jiang
  • Chen Luo
  • Annette Borchers
  • Shanshan Ma
  • Akila Sadasivam
  • Florence L Marlow
  • Janina Schwenty-Lara
  • Matthew Lovatt
  • Yumei Zhou
  • Shijie Tao

Detail Information

Publications46

  1. ncbi Functional interaction of vega2 and goosecoid homeobox genes in zebrafish
    A Kawahara
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genesis 28:58-67. 2000
    ..Here, we describe a novel Vega family homeobox gene, vega2. Expression of vega2 is initiated at the ventral blastoderm margin during blastula stages, and by gastrulation ..
  2. doi Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization
    Birgit Kagermeier-Schenk
    Biotechnology Center and Center for Regenerative Therapies, Technische Universitat Dresden, Tatzberg 47, 01307 Dresden, Germany
    Dev Cell 21:1129-43. 2011
    ..These results suggest that Waif1 modulates pathway selection in Wnt-receiving cells...
  3. doi A direct role for Wnt8 in ventrolateral mesoderm patterning
    Kevin D Baker
    Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
    Dev Dyn 239:2828-36. 2010
    ..Thus, Wnt8 and BMP signaling have independent roles during vertebrate ventrolateral mesoderm development that can be identified through loss-of-function analysis...
  4. pmc Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like
    Hyunju Ro
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 2425, USA
    Nat Cell Biol 11:1121-7. 2009
    ..These studies introduce a ubiquitin ligase, Lnx-l, as a balancing modulator of axial patterning in the zebrafish embryo...
  5. doi Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish
    Maria Vega C Flores
    Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
    Nat Cell Biol 10:346-52. 2008
    ..Among key zygotic ventralizing factors are the bone morphogenetic proteins (Bmps) and the Vent homeodomain family; the latter act as repressors of dorsal organizer gene transcription...
  6. ncbi WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation
    Marie Christine Ramel
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Dev Biol 287:237-48. 2005
    ..non-axial mesoderm into multiple D/V fate domains is known to involve zygotic Wnt8 and BMP signaling as well as the Vent/Vox/Ved family of transcriptional repressors, how levels of signaling activity are translated into differential ..
  7. ncbi Repression of the vertebrate organizer by Wnt8 is mediated by Vent and Vox
    Marie Christine Ramel
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Development 131:3991-4000. 2004
    ..suggest that Wnt8 achieves this restriction by regulating the early expression of the transcriptional repressors Vent and Vox. Our data show that vent and vox are direct transcriptional targets of Wnt8/beta-catenin...
  8. ncbi Patterning the early zebrafish by the opposing actions of bozozok and vox/vent
    A E Melby
    Department of Biochemistry and Center for Developmental Biology, University of Washington, Seattle 98195 7350, USA
    Dev Biol 224:275-85. 2000
    ..Both of the zebrafish genes, which we have named vox and vent, are potent ventralizing factors in both zebrafish and Xenopus embryos...
  9. ncbi A role for MKP3 in axial patterning of the zebrafish embryo
    Michael Tsang
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Development 131:2769-79. 2004
    ..Thus, mkp3 encodes a feedback attenuator of the FGF pathway, the expression of which is initiated at an early stage so as to ensure correct FGF signaling levels at the time of axial patterning...
  10. ncbi A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organizer formation in zebrafish
    Takashi Shimizu
    Department of Molecular Oncology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Mech Dev 118:125-38. 2002
    ..ved's sequence and expression profile were similar to those of vox/vega1 and vent/vega2. Like Vox/Vega1 and Vent/Vega2, Ved acted as a transcriptional repressor...
  11. ncbi The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish
    Y Imai
    Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Development 128:2407-20. 2001
    ..While the zebrafish genes vox (vega1) and vent (vega2) both have ventralizing activity in overexpression assays, loss-of-function studies are needed to determine ..
  12. pmc Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents
    Maximilian Schuff
    Institute of Biochemistry, University of Ulm, Ulm, Germany
    Stem Cells Dev 21:1225-38. 2012
    ..The closest homologs of Nanog in Xenopus are the Vent proteins. We, therefore, investigated whether the Xvent genes might substitute for Nanog function in Xenopus...
  13. ncbi Overexpression of p204 leads to abnormal embryos and osteogenesis in zebrafish
    Hai Bin Zhao
    School of Life Science, Shandong University, Jinan, China
    Front Biosci (Elite Ed) 3:115-24. 2011
    ..Furthermore, the expressions of some genes (vent, runx2b, osn) involved in dorsoventral patterning and osteogenesis were significantly upregulated after p204 ..
  14. doi Caveolin-1 regulates dorsoventral patterning through direct interaction with beta-catenin in zebrafish
    Saijun Mo
    Key Laboratory of Biodiversity and Conservation of Aquatic Organism, Chinese Academy of Sciences, Wuhan, Hubei 430072, PR China
    Dev Biol 344:210-23. 2010
    ..Thus, maternally expressed zebrafish Cav-1 regulates dorsoventral patterning by limiting nuclear translocation of active beta-catenin...
  15. doi The transcription factor Vox represses endoderm development by interacting with Casanova and Pou2
    Jue Zhao
    Inserm U1024, F 75005 Paris, France
    Development 140:1090-9. 2013
    ..in zebrafish, we identified two of its binding partners as the transcription factors Pou2 and Vox, a member of the Vent group of proteins also involved in the patterning of the gastrula...
  16. doi Maternal control of axial-paraxial mesoderm patterning via direct transcriptional repression in zebrafish
    Ying He
    College of Life Science, Zhejiang University, Hangzhou 310058, Zhejiang, People s Republic of China
    Dev Biol 386:96-110. 2014
    ..These results demonstrated that direct transcriptional repression of the decisive axial mesoderm gene by maternal ventralizing factor is a crucial regulatory mechanism of initiating axial-paraxial mesoderm patterning in vertebrates. ..
  17. doi Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension
    Zhongde Ye
    Key Laboratory of Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Nat Commun 4:2803. 2013
    ..Our results suggest a model in which CD146 acts as a functional Wnt5a receptor in regulating cell migration and convergent extension, turning off the canonical Wnt signalling branch. ..
  18. pmc R-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryos
    Xiaozhi Rong
    Key Laboratory of Marine Drugs Ocean University of China, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, Shandong, China
    PLoS ONE 9:e99514. 2014
    ..Human RSPO3 has similar action when tested in zebrafish embryos. These results suggest that Rspo3 regulates dorsoventral and anteroposterior patterning by negatively regulating the zygotic Wnt/β-catenin signaling in zebrafish embryos. ..
  19. doi The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish
    Teddy Young
    Institute of Medical Biology, Agency for Science, Technology and Research A STAR, 8A Biomedical Grove, 06 06 Immunos, Singapore 138648
    Development 141:3505-16. 2014
    ..Taken together, our results identify Mcc as a novel intracellular effector of non-canonical Wnt5b/Vangl2/Ror2 signaling during vertebrate gastrulation. ..
  20. pmc Negative feedback regulation of Wnt signaling via N-linked fucosylation in zebrafish
    Lei Feng
    Department of Biochemistry, Albert Einstein College of Medicine Yeshiva University, Bronx, NY 10461, USA
    Dev Biol 395:268-86. 2014
    ..These results suggest that Wnt limits its own signaling activity in part via up-regulation of a transporter, slc35c1 that promotes terminal fucosylation and thereby limits Wnt activity. ..
  21. doi PIAS-like protein Zimp7 is required for the restriction of the zebrafish organizer and mesoderm development
    Roberto Moreno-Ayala
    Departamento de Genética del Desarrollo y Fisiología Molecular Instituto de Biotecnología, Universidad Nacional Autonoma de Mexico, Mexico
    Dev Biol 403:89-100. 2015
    ..goosecoid and floating head at the onset of gastrulation and by down-regulation of the ventral markers vox, vent and eve1 indicating loss of the ventrolateral mesoderm...
  22. doi ZDHHC16 modulates FGF/ERK dependent proliferation of neural stem/progenitor cells in the zebrafish telencephalon
    Wei Shi
    Key Laboratory of the Ministry of Education for Experimental Teratology Shandong Provincial Key Laboratory of Mental Disorders, Department of Histology and Embryology, Shandong University School of Medicine, No 44, Wenhua Xi Road, Jinan, Shandong, 250012, PR China
    Dev Neurobiol 76:1014-28. 2016
    ..2016 Wiley Periodicals, Inc. Develop Neurobiol 76: 1014-1028, 2016. ..
  23. doi The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning
    Shi Wei
    State Key Laboratory of Membrane Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
    J Genet Genomics 43:431-8. 2016
    ....
  24. pmc The Vox mRNA and protein expression in zebrafish Pou5f3 MZspg mutant embryos
    Anna Voronina
    A N Bach Institute of Biochemistry, Research Center of Biotechnology RAS, Leninsky pr 33, Moscow 119071, Russia
    Stem Cell Investig 3:79. 2016
    ..This conclusion was based on the study of mRNA expression, but the expression of the Vent-family proteins was not analyzed...
  25. pmc Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation
    Shu Yu Wu
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Biol 10:e1001403. 2012
    ..Our study delineates a novel negative, Gsk3β-independent control mechanism of β-catenin and implicates Ccr7 as a long-hypothesized GPCR regulating vertebrate axis formation...
  26. doi High mobility group B proteins regulate mesoderm formation and dorsoventral patterning during zebrafish and Xenopus early development
    Jian Meng Cao
    School of Life Sciences, Shandong University, 27 Shanda Nan Road, Jinan 250100, China
    Mech Dev 129:263-74. 2012
    ..Therefore, our results suggest that hmgb genes may function to fine-tune the specification and/or dorsoventral patterning of mesoderm during zebrafish and Xenopus development...
  27. doi Dorsal activity of maternal squint is mediated by a non-coding function of the RNA
    Shimin Lim
    Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore 117604
    Development 139:2903-15. 2012
    ..Our findings identify new non-coding functions for the Nodal genes and support a model wherein sqt RNA acts as a scaffold to bind and deliver/sequester maternal factors to future embryonic dorsal...
  28. doi Protein phosphatase 4 cooperates with Smads to promote BMP signaling in dorsoventral patterning of zebrafish embryos
    Shunji Jia
    State Key Laboratory of Biomembrane and Membrane Engineering, Tsinghua Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China
    Dev Cell 22:1065-78. 2012
    ..We conclude that Ppp4c is a critical positive regulator of BMP/Smad signaling during embryonic dorsoventral pattern formation in zebrafish...
  29. doi Zili antagonizes Bmp signaling to regulate dorsal-ventral patterning during zebrafish early embryogenesis
    Dan Li
    Department of Medical Genetics and Division of Morbid Genomics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
    Zoolog Sci 28:397-402. 2011
    ..Meanwhile, overexpression of zili produced opposite effects. In conclusion, our results indicate that zili regulates dorsal-ventral patterning by antagonizing Bmp signaling during early embryogenesis in zebrafish...
  30. pmc Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning
    Iryna Kozmikova
    Institute of Molecular Genetics, Prague, Czech Republic
    PLoS ONE 6:e14650. 2011
    ..In the cephalochordate amphioxus, genes encoding Bmps and transcription factors downstream of Bmp signaling such as Vent are expressed in patterns reminiscent of those of their vertebrate orthologues...
  31. pmc Zebrafish foxo3b negatively regulates canonical Wnt signaling to affect early embryogenesis
    Xun Wei Xie
    Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, People s Republic of China
    PLoS ONE 6:e24469. 2011
    ..Our studies provide an in vivo model for illustrating function of FOXO transcription factors in embryogenesis...
  32. doi Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression
    Heinz Georg Belting
    Developmental Biology, Faculty of Biology, University of Freiburg, Hauptstrasse 1, Freiburg, Germany
    Dev Biol 356:323-36. 2011
    ..Our data reveals a set of direct and indirect interactions of Pou5f1 with the BMP dorsoventral patterning network that serve to fine-tune dorsoventral patterning mechanisms and coordinate patterning with developmental timing...
  33. ncbi Functional and hierarchical interactions among zebrafish vox/vent homeobox genes
    Claudio N Gilardelli
    Department of Biology, University of Milan, Milan, Italy
    Dev Dyn 230:494-508. 2004
    ..In Danio rerio (zebrafish), members of the vox/vent gene family (vox/vega1, vent/vega2, and ved) are thought to share expression patterns and functional properties...
  34. doi Zebrafish eve1 regulates the lateral and ventral fates of mesodermal progenitor cells at the onset of gastrulation
    Jamie L Seebald
    Department of Biological Sciences, Purdue University, 915 W State Street, West Lafayette, IN 47907 2054, USA
    Dev Biol 349:78-89. 2011
    ..of eve1 in MPCs requires the redundant and cooperative functions of Bmp-activated downstream homeobox genes, ved, vent and vox. Inhibition of eve1, ved, vent and vox in double and triple combinations results in dorsalized phenotypes...
  35. pmc SHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo
    Michael J Jurynec
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    Dis Model Mech 3:733-42. 2010
    ..We suggest that modulation of FGF signaling may be a principal function of SHIP2 in mammals...
  36. pmc Zili inhibits transforming growth factor-beta signaling by interacting with Smad4
    Huaqin Sun
    Department of Medical Genetics and Division of Morbid Genomics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
    J Biol Chem 285:4243-50. 2010
    ..This work shows that zili plays a role in early embryogenesis beyond germ line as a novel negative regulator of TGF-beta signaling, extending the function of Piwi proteins in vertebrates...
  37. pmc G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway
    Minyong Chen
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Biol Chem 284:35040-8. 2009
    ..knock-down, as assessed by decreased abundance of beta-catenin and lowered expression of the Wnt target genes cdx4, vent, and axin2. Expression of GRK5 rescues the diminished beta-catenin and axin2 response caused by GRK5 depletion...
  38. pmc Alpha2 macroglobulin-like is essential for liver development in zebrafish
    Sung Kook Hong
    Laboratory of Molecular Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA
    PLoS ONE 3:e3736. 2008
    ....
  39. doi Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways
    Norihito Kishimoto
    Department of Genetics, Yale University School of Medicine, 333 Cedar Street, NSB 393, New Haven, CT 06520, USA
    Dev Cell 14:954-61. 2008
    ..Finally, we show that seahorse constrains the canonical Wnt pathway and promotes the noncanonical Wnt pathway during gastrulation. Together, these data suggest that Seahorse may provide a link between ciliary signals and Wnt pathways...
  40. pmc Maternal induction of ventral fate by zebrafish radar
    Samuel Sidi
    Institut National de la Santé et de la Recherche Médicale U368, Ecole Normale Superieure, 75005 Paris, France
    Proc Natl Acad Sci U S A 100:3315-20. 2003
    ..They might further indicate that maternal TGF-betaRdr and WntCa(2+) pathways complementarily specify ventral cell fates, with the former triggering bmps expression and the latter indirectly repressing genes encoding BMP antagonists...
  41. ncbi smad2 and smad3 are required for mesendoderm induction by transforming growth factor-beta/nodal signals in zebrafish
    Shunji Jia
    Protein Science Laboratory of the Ministry of Education, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China
    J Biol Chem 283:2418-26. 2008
    ..Thus, our data reveal that Nodal signaling and mesendoderm induction depend on Smad2/3 and suggest that transforming growth factor-beta signals other than Nodal also contribute to Smad2/3 signaling and embryonic patterning...
  42. pmc Chordin expression, mediated by Nodal and FGF signaling, is restricted by redundant function of two beta-catenins in the zebrafish embryo
    Máté Varga
    Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mech Dev 124:775-91. 2007
    ..from the organizer, the paraxial domain is the result of axial-derived anti-Wnt signals, which relieve the repression that otherwise is set by the Wnt8/beta-catenin/vox,vent pathway on latent germ-ring Nodal/FGF-activated expression.
  43. pmc Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b
    Stefan Hans
    Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA
    BMC Dev Biol 7:5. 2007
    ..We previously suggested that Foxi1 and Dlx3b may provide competence to form the ear because loss of both foxi1 and dlx3b results in ablation of all otic tissue even in the presence of a fully functional Fgf signaling pathway...
  44. ncbi Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis
    Xueying Lin
    Department of Biochemistry and Molecular Biology Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Dev Biol 303:536-48. 2007
    ..Thus, Med10 appears to be a unique MED subunit that differentially transduces information from distinct signaling pathways during zebrafish embryogenesis...
  45. ncbi Transgenic zebrafish reveal stage-specific roles for Bmp signaling in ventral and posterior mesoderm development
    Ujwal J Pyati
    Department of Biochemistry, University of Washington, Seattle, WA 98195 7350, USA
    Development 132:2333-43. 2005
    ..We conclude that the role of Bmp signaling in the ventral and posterior mesoderm changes as gastrulation proceeds...
  46. ncbi Signals derived from the underlying mesoderm are dispensable for zebrafish neural crest induction
    Jared W Ragland
    Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195 7420, USA
    Dev Biol 276:16-30. 2004
    ....