pmaip1

Summary

Gene Symbol: pmaip1
Description: phorbol-12-myristate-13-acetate-induced protein 1
Alias: zgc:162379, phorbol-12-myristate-13-acetate-induced protein 1, Noxa
Species: zebrafish

Top Publications

  1. pmc Genetic modeling of Li-Fraumeni syndrome in zebrafish
    John M Parant
    Department of Neurobiology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Dis Model Mech 3:45-56. 2010
  2. ncbi Functional characterization of the Bcl-2 gene family in the zebrafish
    E Kratz
    Department of Molecular Oncology, Genentech Inc, South San Francisco, CA 94080, USA
    Cell Death Differ 13:1631-40. 2006
  3. pmc BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals
    C A Jette
    Department of Pediatric Oncology, Harvard Medical School, Boston, MA 02115, USA
    Cell Death Differ 15:1063-72. 2008
  4. doi Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish
    Ji Eun Choi
    College of Veterinary Medicine, Seoul National University, 599 Gwanak, Gwanak, Seoul, 151 742, Republic of Korea
    Aquat Toxicol 100:151-9. 2010
  5. doi Exposure to benzidine caused apoptosis and malformation of telencephalon region in zebrafish
    Mark Hung Chih Chen
    Department of Biotechnology, Hungkuang University, Taichung, 43302, Taiwan
    Environ Toxicol 29:1428-36. 2014
  6. pmc Analysis of apoptosis in zebrafish embryos by whole-mount immunofluorescence to detect activated Caspase 3
    Shelly Sorrells
    Department of Oncological Sciences, University of Utah
    J Vis Exp . 2013
  7. pmc Zebrafish Noxa promotes mitosis in early embryonic development and regulates apoptosis in subsequent embryogenesis
    J X Zhong
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate University of the Chinese Academy of Sciences, Wuhan, China
    Cell Death Differ 21:1013-24. 2014
  8. doi Indium and indium tin oxide induce endoplasmic reticulum stress and oxidative stress in zebrafish (Danio rerio)
    Nadja Rebecca Brun
    University of Applied Sciences and Arts Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH 4132 Muttenz, Switzerland
    Environ Sci Technol 48:11679-87. 2014
  9. doi Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial bone formation
    Tatiana Hochgreb-Hägele
    Division of Biology, California Institute of Technology, 1200 E California Blvd, MC139 74, Pasadena, CA 91125, USA Electronic address
    Dev Biol 400:23-32. 2015
  10. doi Low-intensity pulsed ultrasound induces apoptosis in osteoclasts: Fish scales are a suitable model for the analysis of bone metabolism by ultrasound
    Nobuo Suzuki
    Noto Marine Laboratory, Division of Marine Environmental Studies, Institute of Nature and Environmental Technology, Kanazawa University, Noto, Ishikawa 927 0553, Japan Electronic address
    Comp Biochem Physiol A Mol Integr Physiol 195:26-31. 2016

Scientific Experts

  • Nobuo Suzuki
  • Tatiana Hochgreb-Hägele
  • Verena Christen
  • Mauro S Porcel de Peralta
  • Simone Rutz da Costa
  • J X Zhong
  • Nadja Rebecca Brun
  • Mark Hung Chih Chen
  • Karl Fent
  • Shelly Sorrells
  • Hee Yeon Jeon
  • Wei Lun Wang
  • Ji Eun Choi
  • John M Parant
  • Anirban Chakraborty
  • C A Jette
  • E Kratz
  • Maurício da Costa Monteiro
  • Maria R Passos-Bueno
  • Flavio Manoel Rodrigues da Silva Júnior
  • Nora B Calcaterra
  • Valeria S Mouguelar
  • María Antonella Sdrigotti
  • Felipe A A Ishiy
  • Roberto D Fanganiello
  • Juliana Zomer Sandrini
  • Gabriela Coux
  • Li Sung Hsu
  • J F Gui
  • L Zhou
  • Jia lun Wu
  • Jen Ning Tsai
  • Chi Wei Yeh
  • Z Li
  • Li Chi Hsu
  • You Cheng Hseu
  • Gerhard Furrer
  • Y Wang
  • Martinus Capelle
  • Rodney A Stewart
  • Cristhian Toruno
  • Hyunsook Lee
  • Cicely Jette
  • Ching Chun Lin
  • Gen Hwa Lin
  • Ming Wei Lu
  • Jen Leih Wu
  • Hong Yi Gong
  • Jiann Ruey Hong
  • Wangta Liu
  • Stephen A George
  • H Joseph Yost
  • Soohee Kim
  • Doug Young Ryu
  • Jin Hee Ahn
  • Jongheop Yi
  • Pilju Youn
  • Joseph A Holden
  • Kwangsik Park
  • Jin Seok Kang
  • Sayomi Higa
  • Tamayo Uechi
  • Hidetsugu Torihara
  • Naoya Kenmochi
  • U J Pyati
  • D M Langenau
  • A M Flanagan
  • A Letai
  • A T Look
  • S Carbonneau
  • J Ryan
  • R A Stewart
  • R Hart
  • K Mukhyala
  • J Zha
  • A Ashkenazi
  • A Strasser
  • H Stern
  • P M Eimon

Detail Information

Publications16

  1. pmc Genetic modeling of Li-Fraumeni syndrome in zebrafish
    John M Parant
    Department of Neurobiology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Dis Model Mech 3:45-56. 2010
    ....
  2. ncbi Functional characterization of the Bcl-2 gene family in the zebrafish
    E Kratz
    Department of Molecular Oncology, Genentech Inc, South San Francisco, CA 94080, USA
    Cell Death Differ 13:1631-40. 2006
    ..These data indicate substantial functional similarity between zebrafish and mammalian Bcl-2 family members, and establish the zebrafish as a relevant model for studying the intrinsic apoptosis pathway...
  3. pmc BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals
    C A Jette
    Department of Pediatric Oncology, Harvard Medical School, Boston, MA 02115, USA
    Cell Death Differ 15:1063-72. 2008
    ....
  4. doi Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish
    Ji Eun Choi
    College of Veterinary Medicine, Seoul National University, 599 Gwanak, Gwanak, Seoul, 151 742, Republic of Korea
    Aquat Toxicol 100:151-9. 2010
    ..In addition, the p53-related pro-apoptotic genes Bax, Noxa, and p21 were upregulated after treatment with AgNPs...
  5. doi Exposure to benzidine caused apoptosis and malformation of telencephalon region in zebrafish
    Mark Hung Chih Chen
    Department of Biotechnology, Hungkuang University, Taichung, 43302, Taiwan
    Environ Toxicol 29:1428-36. 2014
    ..Real-time polymerase chain reaction analysis also showed that benzidine treatment affected p53, bax, and noxa expression...
  6. pmc Analysis of apoptosis in zebrafish embryos by whole-mount immunofluorescence to detect activated Caspase 3
    Shelly Sorrells
    Department of Oncological Sciences, University of Utah
    J Vis Exp . 2013
    ..Overall, the Casp3 assay represents a robust, highly reproducible assay in which to analyze apoptotic cells in early zebrafish embryos. ..
  7. pmc Zebrafish Noxa promotes mitosis in early embryonic development and regulates apoptosis in subsequent embryogenesis
    J X Zhong
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate University of the Chinese Academy of Sciences, Wuhan, China
    Cell Death Differ 21:1013-24. 2014
    b>Noxa functions in apoptosis and immune system of vertebrates, but its activities in embryo development remain unclear...
  8. doi Indium and indium tin oxide induce endoplasmic reticulum stress and oxidative stress in zebrafish (Danio rerio)
    Nadja Rebecca Brun
    University of Applied Sciences and Arts Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH 4132 Muttenz, Switzerland
    Environ Sci Technol 48:11679-87. 2014
    ..Our study provides first evidence of ER stress and oxidative stress induction by In(NO3)3 and ITO indicating a critical toxicological profile that needs further investigation. ..
  9. doi Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial bone formation
    Tatiana Hochgreb-Hägele
    Division of Biology, California Institute of Technology, 1200 E California Blvd, MC139 74, Pasadena, CA 91125, USA Electronic address
    Dev Biol 400:23-32. 2015
    ..Taken together, the results suggest that Znf385C acts as a developmental switch for p53 function that modulates cell cycle arrest of chondrocytes and regulates timing of jaw cartilage maturation and ossification. ..
  10. doi Low-intensity pulsed ultrasound induces apoptosis in osteoclasts: Fish scales are a suitable model for the analysis of bone metabolism by ultrasound
    Nobuo Suzuki
    Noto Marine Laboratory, Division of Marine Environmental Studies, Institute of Nature and Environmental Technology, Kanazawa University, Noto, Ishikawa 927 0553, Japan Electronic address
    Comp Biochem Physiol A Mol Integr Physiol 195:26-31. 2016
    ..Thus, we are the first to demonstrate that LIPUS directly functions to osteoclasts and to conclude that LIPUS directly causes apoptosis in osteoclasts shortly after exposure. ..
  11. doi Methylene blue toxicity in zebrafish cell line is dependent on light exposure
    Simone Rutz da Costa
    Programa de Pós Graduação em Ciências Fisiológicas Fisiologia Animal Comparada, Universidade Federal do Rio Grande FURG, Av Itália km 8, 96203 900, Rio Grande, Rio Grande do Sul, Brazil
    Cell Biol Int 40:895-905. 2016
    ..However, the pathways leading to apoptosis in this model appear to be dependent on the type of MB exposure (in the presence or absence of PAR). ..
  12. pmc Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes
    Mauro S Porcel de Peralta
    IBR Instituto de Biologia Molecular y Celular de Rosario, Consejo Nacional de Investigaciones Cientificas y Tecnicas CONICET, Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional de Rosario UNR, Ocampo y Esmeralda, Rosario, 2000 Argentina
    Cell Death Dis 7:e2397. 2016
    ..Based on this, we suggest CNBP as an additional target for new alternative therapeutic treatments to reduce craniofacial defects not only in TCS but also in other neurocristopathies...
  13. doi Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish
    Verena Christen
    University of Applied Sciences and Arts Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH 4132 Muttenz, Switzerland
    Toxicol Appl Pharmacol 272:519-28. 2013
    ..1 and 5mg/L AgNPs. Furthermore, transcriptional alterations occurred in the pro-apoptotic genes Noxa and p21. The ER stress response was strong in ZFL cells and occurred in zebrafish embryos as well...
  14. doi Depletion of Aurora-A in zebrafish causes growth retardation due to mitotic delay and p53-dependent cell death
    Hee Yeon Jeon
    Department of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea
    FEBS J 280:1518-30. 2013
    ..The clinical implications of these results relate to the indication that Aurora-A inhibitors may be effective towards cancers with intact p53...
  15. pmc Loss of ribosomal protein L11 affects zebrafish embryonic development through a p53-dependent apoptotic response
    Anirban Chakraborty
    Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan
    PLoS ONE 4:e4152. 2009
    ..These results suggest that ribosomal dysfunction due to the loss of L11 activates a p53-dependent checkpoint response to prevent improper embryonic development...
  16. pmc Stage-specific expression of TNFα regulates bad/bid-mediated apoptosis and RIP1/ROS-mediated secondary necrosis in Birnavirus-infected fish cells
    Wei Lun Wang
    Institute of Fisheries Science, National Taiwan University, Taipei, Taiwan, Republic of China
    PLoS ONE 6:e16740. 2011
    ..i.). Taken together, our results indicate that IPNV triggers two death pathways via up-stream induction of the pro-inflammatory cytokine TNFα, and these results may provide new insights into the pathogenesis of RNA viruses...