mcm5

Summary

Gene Symbol: mcm5
Description: minichromosome maintenance complex component 5
Alias: wu:fb34a06, DNA replication licensing factor MCM5, MCM5 minichromosome maintenance deficient 5
Species: zebrafish

Top Publications

  1. ncbi Minichromosome maintenance proteins as markers for proliferation zones during embryogenesis
    Soojin Ryu
    Developmental Biology, Institute Biology 1, University of Freiburg, Freiburg, Germany
    Cell Cycle 5:1140-2. 2006
  2. pmc Large-scale live imaging of adult neural stem cells in their endogenous niche
    Nicolas Dray
    Paris Saclay Institute for Neuroscience, CNRS UMR9197 Université Paris Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif sur Yvette F 91198, France
    Development 142:3592-600. 2015
  3. doi ZDHHC16 modulates FGF/ERK dependent proliferation of neural stem/progenitor cells in the zebrafish telencephalon
    Wei Shi
    Key Laboratory of the Ministry of Education for Experimental Teratology Shandong Provincial Key Laboratory of Mental Disorders, Department of Histology and Embryology, Shandong University School of Medicine, No 44, Wenhua Xi Road, Jinan, Shandong, 250012, PR China
    Dev Neurobiol 76:1014-28. 2016
  4. pmc A Nuclear Role for miR-9 and Argonaute Proteins in Balancing Quiescent and Activated Neural Stem Cell States
    Shauna Katz
    Zebrafish Neurogenetics Group, Paris Saclay Institute of Neuroscience Neuro PSI, UMR 9197, CNRS University Paris Sud, Avenue de la Terrasse, 91190 Gif sur Yvette, France
    Cell Rep 17:1383-1398. 2016
  5. pmc Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium
    Alessandro Alunni
    Institute of Neurobiology A Fessard, Laboratory of Neurobiology and Development, CNRS UPR3294, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, F 91198 Gif sur Yvette, France
    Development 140:3335-47. 2013
  6. doi Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome
    Louise S Bicknell
    Medical Research Council MRC Human Genetics Unit HGU, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK
    Nat Genet 43:350-5. 2011
  7. doi Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2
    Andrea Wolf
    Developmental Genetics of the Nervous System, Max Planck Institute for Medical Research, Heidelberg, Germany
    Development 140:1762-73. 2013
  8. pmc Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis
    Soojin Ryu
    Developmental Biology, Institute Biology 1, University of Freiburg, Hauptstrasse 1, D 79104 Freiburg, Germany
    Proc Natl Acad Sci U S A 102:18467-72. 2005
  9. pmc Differential roles of transcriptional mediator complex subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 during zebrafish retinal development
    Katrin Durr
    Department of Developmental Biology, Institute for Biology 1, University of Freiburg, Germany
    Genetics 174:693-705. 2006
  10. ncbi her5 expression reveals a pool of neural stem cells in the adult zebrafish midbrain
    Prisca Chapouton
    Zebrafish Neurogenetics Junior Research Group, Institute of Virology, Technical University Munich, Trogerstrasse 4b, D 81675, Munich, Germany
    Development 133:4293-303. 2006

Scientific Experts

  • Prisca Chapouton
  • Soojin Ryu
  • Sergey V Prykhozhij
  • Laure Bally-Cuif
  • Alessandro Alunni
  • Shauna Katz
  • Wei Shi
  • Marion Coolen
  • Nicolas Dray
  • Monika Krecsmarik
  • Andrea Wolf
  • Louise S Bicknell
  • Martin März
  • Hua Ling Chen
  • Xiaolin Liu
  • Katrin Durr
  • Ming Gao
  • Xueran Chen
  • Aijun Hao
  • Delphine Cussigh
  • Yang Yang
  • Noelia Urbán
  • Chen Wang
  • Francois Guillemot
  • Zhaoxia Du
  • Isabelle Blomfield
  • Yao Yao
  • Kun He
  • Fen Wang
  • Emmanuel Beaurepaire
  • Sebastien Bedu
  • Willy Supatto
  • Nelly Vuillemin
  • Adriana Bosco
  • Luyuan Pan
  • Cecilia B Moens
  • Sonya Galant
  • Penny A Jeggo
  • Carol Wise
  • Andrew P Jackson
  • Mark O'Driscoll
  • Michael Bober
  • Carol Anne Martin
  • Nouriya Al Sanna
  • Tom Stiff
  • Anna Klingseisen
  • Andrea Leitch
  • Sarah Walker
  • Claudia Kerzendorfer
  • Patricia Yeyati
  • Diana Johnson
  • Chen Sok Lam
  • Nicolas Diotel
  • Colette Vaillant
  • Kenneth K Wu
  • Uwe Strahle
  • Birgit Hesl
  • Masanari Takamiya
  • Chiou Hwa Yuh
  • Olivier Kah
  • Lingfei Luo
  • Chun Li
  • Yaoguang Zhang
  • Sizhou Huang
  • Jun Ma
  • Wolfgang Driever
  • Alida Filippi
  • Anne Kathrin Ettl
  • Jochen Holzschuh
  • Iain T Shepherd

Detail Information

Publications16

  1. ncbi Minichromosome maintenance proteins as markers for proliferation zones during embryogenesis
    Soojin Ryu
    Developmental Biology, Institute Biology 1, University of Freiburg, Freiburg, Germany
    Cell Cycle 5:1140-2. 2006
    ....
  2. pmc Large-scale live imaging of adult neural stem cells in their endogenous niche
    Nicolas Dray
    Paris Saclay Institute for Neuroscience, CNRS UMR9197 Université Paris Sud, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, Gif sur Yvette F 91198, France
    Development 142:3592-600. 2015
    ..This methodology enables us to describe the frequency, distribution and modes of aNSCs divisions across the entire germinal zone of the adult pallium, and to highlight regional differences in these parameters. ..
  3. doi ZDHHC16 modulates FGF/ERK dependent proliferation of neural stem/progenitor cells in the zebrafish telencephalon
    Wei Shi
    Key Laboratory of the Ministry of Education for Experimental Teratology Shandong Provincial Key Laboratory of Mental Disorders, Department of Histology and Embryology, Shandong University School of Medicine, No 44, Wenhua Xi Road, Jinan, Shandong, 250012, PR China
    Dev Neurobiol 76:1014-28. 2016
    ..2016 Wiley Periodicals, Inc. Develop Neurobiol 76: 1014-1028, 2016. ..
  4. pmc A Nuclear Role for miR-9 and Argonaute Proteins in Balancing Quiescent and Activated Neural Stem Cell States
    Shauna Katz
    Zebrafish Neurogenetics Group, Paris Saclay Institute of Neuroscience Neuro PSI, UMR 9197, CNRS University Paris Sud, Avenue de la Terrasse, 91190 Gif sur Yvette, France
    Cell Rep 17:1383-1398. 2016
    ..We propose a conserved non-canonical role for nuclear miR-9/Agos in controlling the balance between NSC quiescence and activation, a key step in maintaining adult germinal pools...
  5. pmc Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium
    Alessandro Alunni
    Institute of Neurobiology A Fessard, Laboratory of Neurobiology and Development, CNRS UPR3294, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, F 91198 Gif sur Yvette, France
    Development 140:3335-47. 2013
    ..They implicate Notch3 at the top of this hierarchy to gate NSC activation and amplification, protecting the homeostasis of adult NSC reservoirs under physiological conditions. ..
  6. doi Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome
    Louise S Bicknell
    Medical Research Council MRC Human Genetics Unit HGU, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK
    Nat Genet 43:350-5. 2011
    ..These findings establish a novel mechanism for the pathogenesis of microcephalic dwarfism and show a surprising but important developmental impact of impaired origin licensing...
  7. doi Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2
    Andrea Wolf
    Developmental Genetics of the Nervous System, Max Planck Institute for Medical Research, Heidelberg, Germany
    Development 140:1762-73. 2013
    ....
  8. pmc Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis
    Soojin Ryu
    Developmental Biology, Institute Biology 1, University of Freiburg, Hauptstrasse 1, D 79104 Freiburg, Germany
    Proc Natl Acad Sci U S A 102:18467-72. 2005
    ..Here, we present positional cloning of a zebrafish mcm5 mutation and characterization of its retina phenotype...
  9. pmc Differential roles of transcriptional mediator complex subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 during zebrafish retinal development
    Katrin Durr
    Department of Developmental Biology, Institute for Biology 1, University of Freiburg, Germany
    Genetics 174:693-705. 2006
    ....
  10. ncbi her5 expression reveals a pool of neural stem cells in the adult zebrafish midbrain
    Prisca Chapouton
    Zebrafish Neurogenetics Junior Research Group, Institute of Virology, Technical University Munich, Trogerstrasse 4b, D 81675, Munich, Germany
    Development 133:4293-303. 2006
    ..In addition, the first transcription factor characteristic of this cell population, Her5, points to the E(Spl) as a promising family of candidate adult neural stem cell regulators...
  11. pmc Distinct roles of Shh and Fgf signaling in regulating cell proliferation during zebrafish pectoral fin development
    Sergey V Prykhozhij
    Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg, Germany
    BMC Dev Biol 8:91. 2008
    ..Sonic hedgehog (Shh) directs pattern formation along the anterior/posterior axis of the limb, whereas several Fgfs in combination direct pattern formation along the proximal/distal axis of the limb...
  12. pmc NF-kappaB and Snail1a coordinate the cell cycle with gastrulation
    Xiaolin Liu
    Key Laboratory of Aquatic Organism Reproduction and Development, Ministry of Education, Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University, Beibei, Chongqing, China
    J Cell Biol 184:805-15. 2009
    ..In effect, the cell cycle coordinates the delamination of mesendodermal cells through the transcription of Snail1a. Our results suggest a molecular mechanism by which NF-kappaB and Snail1a coordinate the cell cycle through gastrulation...
  13. doi Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon
    Martin März
    Institute for Toxicology and Genetics, Forschungszentrum Karlsruhe in the Helmholtz Association, Karlsruhe Institute of Technology, Postfach 3640, 76021 Karlsruhe, Germany
    Glia 58:870-88. 2010
    ..of the adult zebrafish telencephalon (identified by expression of proliferating cell nuclear antigen (PCNA), MCM5, or bromodeoxyuridine incorporation)...
  14. pmc Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis
    Hua Ling Chen
    Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan
    PLoS ONE 5:e9318. 2010
    ..Nestin is expressed in neural progenitor cells (NPC) of developing brain. Despite its wide use as an NPC marker, the function of nestin in embryo development is unclear...
  15. doi Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells
    Prisca Chapouton
    Zebrafish Neurogenetics Department, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, D 85764 Neuherberg, Germany
    J Neurosci 30:7961-74. 2010
    ....