irbp

Summary

Gene Symbol: irbp
Description: interphotoreceptor retinoid-binding protein
Alias: retinol-binding protein 3, irbp gene 2
Species: zebrafish

Top Publications

  1. pmc Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development
    Kunal Rai
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112, USA
    Mol Cell Biol 26:7077-85. 2006
  2. ncbi Coordination between production and turnover of interphotoreceptor retinoid-binding protein in zebrafish
    L L Cunningham
    Graduate Program in Neuroscience, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Invest Ophthalmol Vis Sci 41:3590-9. 2000
  3. pmc Developmental stage-specific regulation of the circadian clock by temperature in zebrafish
    Kajori Lahiri
    Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann von Helmholtz Platz 1, 76344 Eggenstein Leopoldshafen, Germany Institute of Functional Interfaces, Karlsruhe Institute of Technology, Hermann von Helmholtz Platz 1, 76344 Eggenstein Leopoldshafen, Germany
    Biomed Res Int 2014:930308. 2014
  4. pmc Zebrafish Lbh-like Is Required for Otx2-mediated Photoreceptor Differentiation
    Wen Hua Li
    1 State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, 2 Graduate University of the Chinese Academy of Sciences, Wuhan 430072, China
    Int J Biol Sci 11:688-700. 2015
  5. pmc Structure of zebrafish IRBP reveals fatty acid binding
    Debashis Ghosh
    Department of Pharmacology, State University of New York Upstate Medical University, Syracuse, NY, USA Electronic address
    Exp Eye Res 140:149-58. 2015
  6. pmc Fold conservation and proteolysis in zebrafish IRBP structure: Clues to possible enzymatic function?
    Debashis Ghosh
    Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA Electronic address
    Exp Eye Res 147:78-84. 2016
  7. ncbi Zebrafish cone-rod (crx) homeobox gene promotes retinogenesis
    Yu chi Shen
    Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109 0616, USA
    Dev Biol 269:237-51. 2004
  8. pmc Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development
    Lincoln D Nadauld
    Department of Oncological Sciences and Medicinal Chemistry and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 103:13409-14. 2006
  9. pmc Differential expression of photoreceptor-specific genes in the retina of a zebrafish cadherin2 mutant glass onion and zebrafish cadherin4 morphants
    Q Liu
    Department of Biology, University of Akron, 302 Buchtel Common, Akron, OH 44325, USA
    Exp Eye Res 84:163-75. 2007
  10. pmc Interphotoreceptor retinoid-binding protein gene structure in tetrapods and teleost fish
    John M Nickerson
    Ophthalmology Department, Emory University, Atlanta, GA 30322, USA
    Mol Vis 12:1565-85. 2006

Research Grants

  1. Genoplasty in Ocular Gene Therapy
    JOHN NICKERSON; Fiscal Year: 2004

Scientific Experts

  • Debashis Ghosh
  • Qin Liu
  • G R Li
  • JOHN NICKERSON
  • Kunal Rai
  • Stephanie Chidester
  • David A Jones
  • Wen Hua Li
  • Lincoln D Nadauld
  • Kajori Lahiri
  • Bradley R Cairns
  • Smitha R James
  • Adam R Karpf
  • John M Nickerson
  • Elizabeth J Manos
  • Yu chi Shen
  • Jian Fang Gui
  • Yang Wang
  • Jian Tao Shi
  • Yan Jing Yang
  • Zhi Li
  • Li Zhou
  • Nadine Froehlich
  • Daniela Vallone
  • Nicholas S Foulkes
  • Andreas Heyd
  • L L Cunningham
  • Itrat F Jafri
  • Imelda T Sandoval
  • Ruth A Frey
  • Vincent T Ciavatta
  • H Joseph Yost
  • Peter W Peterson
  • Deborah L Stenkamp
  • Dawne N Shelton
  • Chris M Ireland
  • Talmage Broadbent
  • Pamela A Raymond
  • F Gonzalez-Fernandez

Detail Information

Publications11

  1. pmc Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development
    Kunal Rai
    Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112, USA
    Mol Cell Biol 26:7077-85. 2006
    ..Our results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 and that, together, Dnmt1 and Suv39h1 help guide the terminal differentiation of particular tissues...
  2. ncbi Coordination between production and turnover of interphotoreceptor retinoid-binding protein in zebrafish
    L L Cunningham
    Graduate Program in Neuroscience, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Invest Ophthalmol Vis Sci 41:3590-9. 2000
    Interphotoreceptor retinoid-binding protein (IRBP), which is secreted by the photoreceptors of most vertebrates, is the major soluble protein component of the interphotoreceptor matrix (IPM)...
  3. pmc Developmental stage-specific regulation of the circadian clock by temperature in zebrafish
    Kajori Lahiri
    Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann von Helmholtz Platz 1, 76344 Eggenstein Leopoldshafen, Germany Institute of Functional Interfaces, Karlsruhe Institute of Technology, Hermann von Helmholtz Platz 1, 76344 Eggenstein Leopoldshafen, Germany
    Biomed Res Int 2014:930308. 2014
    ..Furthermore, we show that following the 5-9 somite stage, the expression of zfper1b is regulated by acute temperature shifts...
  4. pmc Zebrafish Lbh-like Is Required for Otx2-mediated Photoreceptor Differentiation
    Wen Hua Li
    1 State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, 2 Graduate University of the Chinese Academy of Sciences, Wuhan 430072, China
    Int J Biol Sci 11:688-700. 2015
    ..specifically inhibits expression of multiple photoreceptor-specific genes, such as opsins, gnat1, gnat2 and irbp. Interestingly, otx2 expression in the morphants is not significantly reduced until 32 hpf when lbh-like begins to ..
  5. pmc Structure of zebrafish IRBP reveals fatty acid binding
    Debashis Ghosh
    Department of Pharmacology, State University of New York Upstate Medical University, Syracuse, NY, USA Electronic address
    Exp Eye Res 140:149-58. 2015
    Interphotoreceptor retinoid-binding protein (IRBP) has a remarkable role in targeting and protecting all-trans and 11-cis retinol, and 11-cis retinal during the rod and cone visual cycles...
  6. pmc Fold conservation and proteolysis in zebrafish IRBP structure: Clues to possible enzymatic function?
    Debashis Ghosh
    Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA Electronic address
    Exp Eye Res 147:78-84. 2016
    Multiple functions for Interphotoreceptor Retinoid-Binding Protein (IRBP) may explain its localization in the retina, vitreous and pineal gland and association with retinitis pigmentosa and myopia...
  7. ncbi Zebrafish cone-rod (crx) homeobox gene promotes retinogenesis
    Yu chi Shen
    Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109 0616, USA
    Dev Biol 269:237-51. 2004
    ..These results suggest novel functions for zebrafish crx during retinal specification and differentiation...
  8. pmc Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development
    Lincoln D Nadauld
    Department of Oncological Sciences and Medicinal Chemistry and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 103:13409-14. 2006
    ....
  9. pmc Differential expression of photoreceptor-specific genes in the retina of a zebrafish cadherin2 mutant glass onion and zebrafish cadherin4 morphants
    Q Liu
    Department of Biology, University of Akron, 302 Buchtel Common, Akron, OH 44325, USA
    Exp Eye Res 84:163-75. 2007
    ..photoreceptors, we have analyzed expression patterns of several photoreceptor-specific genes (crx, gnat1, gnat2, irbp, otx5, rod opsin, rx1, and uv opsin) and/or a cone photoreceptor marker (zpr-1) in the retina of a zebrafish ..
  10. pmc Interphotoreceptor retinoid-binding protein gene structure in tetrapods and teleost fish
    John M Nickerson
    Ophthalmology Department, Emory University, Atlanta, GA 30322, USA
    Mol Vis 12:1565-85. 2006
    The interphotoreceptor retinoid-binding protein (IRBP) gene possesses an unusual structure, encoding multiple Repeats, each consisting of about 300 amino acids...
  11. pmc Dnmt3 and G9a cooperate for tissue-specific development in zebrafish
    Kunal Rai
    Department of Oncological Sciences, oward Hughes Medical Institute, and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    J Biol Chem 285:4110-21. 2010
    ..We propose a model wherein specific DNMT-histone methyltransferase networks are utilized to silence critical regulators of cell fate in a tissue-specific manner...

Research Grants1

  1. Genoplasty in Ocular Gene Therapy
    JOHN NICKERSON; Fiscal Year: 2004
    ..abstract_text> ..