fabp7a

Summary

Gene Symbol: fabp7a
Description: fatty acid binding protein 7, brain, a
Alias: B-FABP, D168, fabp7, wu:fb62f07, wu:fq20b08, fatty acid binding protein 7, brain, a, blbp, brain lipid-binding protein
Species: zebrafish

Top Publications

  1. ncbi Differential expression of duplicated genes for brain-type fatty acid-binding proteins (fabp7a and fabp7b) during early development of the CNS in zebrafish (Danio rerio)
    Rong Zong Liu
    Department of Biology, Dalhousie University, Halifax, NS, Canada B3H 4J1
    Gene Expr Patterns 4:379-87. 2004
  2. ncbi Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome
    Mukesh K Sharma
    Department of Biology, Dalhousie University, Halifax, NS, Canada
    FEBS J 273:3216-29. 2006
  3. ncbi High transcript level of fatty acid-binding protein 11 but not of very low-density lipoprotein receptor is correlated to ovarian follicle atresia in a teleost fish (Solea senegalensis)
    Maria J Agulleiro
    Institut de Recerca i Tecnologia Agroalimentàries Center of Aquaculture, Sant Carles de la Ràpita, Tarragona 43540, Spain
    Biol Reprod 77:504-16. 2007
  4. pmc Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization or neofunctionalization of duplicated genes
    Santhosh Karanth
    Department of Biology, Dalhousie University, Halifax, Nova Scotia, B3H 4J1, Canada
    BMC Evol Biol 9:219. 2009
  5. ncbi Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression
    Rong Zong Liu
    Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada
    FEBS J 272:3561-71. 2005
  6. doi Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish
    Qing Liu
    School of Freshwater Sciences, University of Wisconsin Milwaukee, 600 E Greenfield Ave, Milwaukee, WI 53204, United States
    Reprod Toxicol 65:272-282. 2016
  7. doi Mapping of brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation
    Nicolas Diotel
    INSERM, UMR 1188 Diabète athérothrombose Thérapies Réunion Océan Indien DéTROI, Plateforme CYROI, Sainte Clotilde, F 97490, France Université de La Réunion, UMR 1188, Sainte Clotilde, F 97490, France INSERM U1085, Universite de Rennes 1, Campus de Beaulieu, Research Institute in Health, Environment and Occupation, SFR Biosit, Rennes Cedex, France Electronic address
    Gene Expr Patterns 20:42-54. 2016
  8. pmc Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness
    Penelope J Boyd
    Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield S10 2HQ, UK Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore Bateson Centre, Department of Biomedical Science, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    Biol Open 4:1336-43. 2015
  9. pmc Swimming-induced exercise promotes hypertrophy and vascularization of fast skeletal muscle fibres and activation of myogenic and angiogenic transcriptional programs in adult zebrafish
    Arjan P Palstra
    Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    BMC Genomics 15:1136. 2014
  10. doi Fatty acid-binding protein (fabp) genes of spotted green pufferfish (Tetraodon nigroviridis): comparative genomics and spatial transcriptional regulation
    Aruloli Thirumaran
    Department of Biology, Dalhousie University, 1355 Oxford Street, Halifax, NS B3H 4R2, Canada
    Genome 57:289-301. 2014

Research Grants

  1. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
  2. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010

Scientific Experts

  • Josep V Planas
  • Nicolas Diotel
  • Austin Hughes
  • Curtis R French
  • Santhosh Karanth
  • Manoj B Parmar
  • Jonathan M Wright
  • Young Ki Bae
  • Rong Zong Liu
  • Eileen M Denovan-Wright
  • Laure Bally-Cuif
  • Shuichi Kani
  • Masahiko Hibi
  • Qing Liu
  • Penelope J Boyd
  • Mohammed Gebriel
  • Arjan P Palstra
  • Lara Dirian
  • B Ju
  • Aruloli Thirumaran
  • Sonya Galant
  • Mukesh K Sharma
  • Alessandro Alunni
  • Cecilia B Moens
  • Jenny R Lenkowski
  • Imelda T Sandoval
  • Christine Thisse
  • Bernard Thisse
  • Ananda B Venkatachalam
  • Wei Zhang
  • YuanXiang Jin
  • Esther Kur
  • Yoko Ito
  • Marijke De Wit
  • Pamela A Raymond
  • Virginie Esain
  • Sen Li
  • Shin Ichi Higashijima
  • Takashi Shimizu
  • Koji Tanabe
  • Ho Kim
  • Robert E Drew
  • Maria J Agulleiro
  • Monica R Rohrschneider
  • Rebecca L Bernardos
  • Birgit Adolf
  • Yuexiang Wang
  • Daniel N Weber
  • Barbara Wimpee
  • Michael J Carvan
  • Shawn L Gerstenberger
  • Tisha King-Heiden
  • Jessica Grzybowski
  • Matthew Dellinger
  • Rebekah H Klingler
  • Jonathan D Wood
  • Sudipto Roy
  • Vincent T Cunliffe
  • P Vogel
  • Herman P Spaink
  • Simon Geir Møller
  • J Lu
  • H E Henson
  • Mireia Rovira
  • C Parupalli
  • Corinne Houart
  • Isabelle Foucher
  • W Chen
  • Shubhangi Prabhudesai
  • Wenbiao Chen
  • Anne Hjelle Bjørnstad
  • David Rizo-Roca
  • J M Spitsbergen
  • Marion Coolen
  • Sebastien Bedu
  • B A Orr
  • Y D Wang
  • Joan Ramon Torrella
  • J L Peters
  • Dominik Piston
  • J Wu
  • Kai Erik Uleberg
  • M R Taylor
  • S Jia
  • Eivind Larssen
  • Elizabeth J Manos
  • Ryan Thummel
  • David A Jones
  • Kornelia Edes
  • Richard Glenn C Delacruz

Detail Information

Publications37

  1. ncbi Differential expression of duplicated genes for brain-type fatty acid-binding proteins (fabp7a and fabp7b) during early development of the CNS in zebrafish (Danio rerio)
    Rong Zong Liu
    Department of Biology, Dalhousie University, Halifax, NS, Canada B3H 4J1
    Gene Expr Patterns 4:379-87. 2004
    ..of four exons encoding 24, 58, 34 and 16 amino acids, respectively, which is identical to the structure of the fabp7a gene previously described...
  2. ncbi Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome
    Mukesh K Sharma
    Department of Biology, Dalhousie University, Halifax, NS, Canada
    FEBS J 273:3216-29. 2006
    ....
  3. ncbi High transcript level of fatty acid-binding protein 11 but not of very low-density lipoprotein receptor is correlated to ovarian follicle atresia in a teleost fish (Solea senegalensis)
    Maria J Agulleiro
    Institut de Recerca i Tecnologia Agroalimentàries Center of Aquaculture, Sant Carles de la Ràpita, Tarragona 43540, Spain
    Biol Reprod 77:504-16. 2007
    ....
  4. pmc Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization or neofunctionalization of duplicated genes
    Santhosh Karanth
    Department of Biology, Dalhousie University, Halifax, Nova Scotia, B3H 4J1, Canada
    BMC Evol Biol 9:219. 2009
    ..FA profiles and the steady-state levels of fabp mRNA and heterogeneous nuclear RNA in intestine, liver, muscle and brain of zebrafish were determined...
  5. ncbi Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression
    Rong Zong Liu
    Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada
    FEBS J 272:3561-71. 2005
    ..The differential and complementary expression patterns of the zebrafish crabp1a and crabp1b genes imply that subfunctionalization may be the mechanism for the retention of both crabp1 duplicated genes in the zebrafish genome...
  6. doi Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish
    Qing Liu
    School of Freshwater Sciences, University of Wisconsin Milwaukee, 600 E Greenfield Ave, Milwaukee, WI 53204, United States
    Reprod Toxicol 65:272-282. 2016
    ..Results from this study provide evidence that food intended for human consumption, with relatively modest levels of MeHg, may induce adverse effects in offspring...
  7. doi Mapping of brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation
    Nicolas Diotel
    INSERM, UMR 1188 Diabète athérothrombose Thérapies Réunion Océan Indien DéTROI, Plateforme CYROI, Sainte Clotilde, F 97490, France Université de La Réunion, UMR 1188, Sainte Clotilde, F 97490, France INSERM U1085, Universite de Rennes 1, Campus de Beaulieu, Research Institute in Health, Environment and Occupation, SFR Biosit, Rennes Cedex, France Electronic address
    Gene Expr Patterns 20:42-54. 2016
    ..glial cells display well-established markers such as the estrogen-synthesizing enzyme (AroB) and the brain lipid binding protein (Blbp), which is known to strongly bind omega-3 polyunsaturated fatty acids such as docosahexaenoic ..
  8. pmc Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness
    Penelope J Boyd
    Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield S10 2HQ, UK Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore Bateson Centre, Department of Biomedical Science, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    Biol Open 4:1336-43. 2015
    ..We therefore suggest that altered Shh signalling may be an important neurodevelopmental factor in the pathobiology of mental illness. ..
  9. pmc Swimming-induced exercise promotes hypertrophy and vascularization of fast skeletal muscle fibres and activation of myogenic and angiogenic transcriptional programs in adult zebrafish
    Arjan P Palstra
    Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    BMC Genomics 15:1136. 2014
    ....
  10. doi Fatty acid-binding protein (fabp) genes of spotted green pufferfish (Tetraodon nigroviridis): comparative genomics and spatial transcriptional regulation
    Aruloli Thirumaran
    Department of Biology, Dalhousie University, 1355 Oxford Street, Halifax, NS B3H 4R2, Canada
    Genome 57:289-301. 2014
    ..The differential tissue-specific distribution of pufferfish fabp transcripts suggests divergent spatial regulation of duplicated pairs of fabp genes. ..
  11. doi Spatial regionalization and heterochrony in the formation of adult pallial neural stem cells
    Lara Dirian
    Institute of Neurobiology A Fessard, Laboratory of Neurobiology and Development, CNRS UPR3294, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, 91198 Gif sur Yvette, France
    Dev Cell 30:123-36. 2014
    ..This dual origin of the pallial germinal zone allows the temporally organized building of pallial territories as a patchwork of juxtaposed compartments. ..
  12. pmc Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway
    B Ju
    Department of Chemical Biology and Therapeutics, St Jude Children s Research Hospital, Memphis, TN, USA
    Oncogenesis 3:e96. 2014
    ..characteristic of radial glia and progenitor cells as transcriptions of radial glia genes cyp19a1b, s100β, blbp, gfap and the stem/progenitor genes nestin and sox2 were significantly upregulated...
  13. doi Comparative genomic organization and tissue-specific transcription of the duplicated fabp7 and fabp10 genes in teleost fishes
    Manoj B Parmar
    Department of Biology, Dalhousie University, 1355 Oxford Street, P O Box 15000, Halifax, NS B3H 4R2, Canada
    Genome 56:691-701. 2013
    ..The tissue-specific distribution of fabp7a, fabp7b, fabp10a, and fabp10b transcripts provides evidence of diverged spatial transcriptional regulation between ..
  14. doi Zebrafish brain proteomics reveals central proteins involved in neurodegeneration
    Mohammed Gebriel
    Centre for Organelle Research, University of Stavanger, Stavanger, Norway
    J Neurosci Res 92:104-15. 2014
    ....
  15. pmc Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling
    Jenny R Lenkowski
    Molecular, Cellular, and Developmental Biology, University of Michigan, 830 N University, Ann Arbor, Michigan, USA
    Glia 61:1687-97. 2013
    ..Tgif1 expression and regulation of TGFβ signaling are implicated in the function of several types of stem cells, but this is the first demonstration that this regulatory network is necessary for regeneration of neurons...
  16. pmc Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium
    Alessandro Alunni
    Institute of Neurobiology A Fessard, Laboratory of Neurobiology and Development, CNRS UPR3294, Team Zebrafish Neurogenetics, Avenue de la Terrasse, Building 5, F 91198 Gif sur Yvette, France
    Development 140:3335-47. 2013
    ..They implicate Notch3 at the top of this hierarchy to gate NSC activation and amplification, protecting the homeostasis of adult NSC reservoirs under physiological conditions. ..
  17. doi Proteomic analysis of hepatic tissue in adult female zebrafish (Danio rerio) exposed to atrazine
    YuanXiang Jin
    College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310032, China
    Arch Environ Contam Toxicol 62:127-34. 2012
    ..The information presented in this study will be helpful in fully understanding the mechanism of the potential effects induced by ATZ in fish...
  18. doi Sex differences in transcriptional expression of FABPs in zebrafish liver after chronic perfluorononanoic acid exposure
    Wei Zhang
    Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, People s Republic of China
    Environ Sci Technol 46:5175-82. 2012
    ..The results indicated that PFNA exposure caused opposite adverse effects on liver TG levels between the sexes in zebrafish possibly due to the opposite expression of FABPs and its upstream genes...
  19. doi The evolutionary relationship of the transcriptionally active fabp11a (intronless) and fabp11b genes of medaka with fabp11 genes of other teleost fishes
    Manoj B Parmar
    Department of Biology, Dalhousie University, Halifax, NS, Canada
    FEBS J 279:2310-21. 2012
    ....
  20. pmc Tissue-specific differential induction of duplicated fatty acid-binding protein genes by the peroxisome proliferator, clofibrate, in zebrafish (Danio rerio)
    Ananda B Venkatachalam
    Department of Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada
    BMC Evol Biol 12:112. 2012
    ..1/fabp1b.2, fabp7a/fabp7b, fabp10a/fabp10b and fabp11a/fabp11b in zebrafish fed different concentrations of clofibrate.
  21. doi Comparative genomics and evolutionary diversification of the duplicated fabp6a and fabp6b genes in medaka and three-spined stickleback
    Manoj B Parmar
    Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada
    Comp Biochem Physiol Part D Genomics Proteomics 7:311-21. 2012
    ..However, the tissue-specific regulation of the fabp6b gene has diverged markedly in medaka and three-spined stickleback since the duplication of the fabp6 gene...
  22. pmc Juxtaposition of chemical and mutation-induced developmental defects in zebrafish reveal a copper-chelating activity for kalihinol F
    Imelda T Sandoval
    Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA
    Chem Biol 20:753-63. 2013
    ..Our data support this mechanism of action for kalihinol F and the utility of zebrafish as an effective system for identifying therapeutic and target pathways. ..
  23. doi Characterization of neural stem cells and their progeny in the adult zebrafish optic tectum
    Yoko Ito
    Department of Life Science and Medical Bio Science, School of Advanced Science and Engineering, Waseda University, 2 2 Wakamatsu cho, Shinjuku ku, Tokyo, 162 8480, Japan
    Dev Biol 342:26-38. 2010
    ..regions are distinguished by the differential expression of several marker genes: pcna, sox2, msi1, elavl3, gfap, fabp7a, and s100beta...
  24. ncbi Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon
    Birgit Adolf
    Institute of Virology, Technical University Munich, Trogerstrasse 4b, D 81675, Munich, Germany
    Dev Biol 295:278-93. 2006
    ....
  25. ncbi Myocyte-specific enhancer factor 2A is essential for zebrafish posterior somite development
    Yuexiang Wang
    Department of Molecular Genetics, Shanghai Medical School and Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, Shanghai 200032, PR China
    Mech Dev 123:783-91. 2006
    ..Microarray studies reveal a number of genes that are differentially expressed in the MEF2A morphants. Our studies suggest that MEF2A is essential for zebrafish posterior somite development...
  26. ncbi Late-stage neuronal progenitors in the retina are radial Müller glia that function as retinal stem cells
    Rebecca L Bernardos
    Neuroscience Program, University of Michigan, Ann Arbor, Michigan 48109 1048, USA
    J Neurosci 27:7028-40. 2007
    ..We conclude that zebrafish Müller glia function as multipotent retinal stem cells that generate retinal neurons by homeostatic and regenerative developmental mechanisms...
  27. pmc Pbx homeodomain proteins pattern both the zebrafish retina and tectum
    Curtis R French
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    BMC Dev Biol 7:85. 2007
    ..Although previous results have demonstrated that Pbx is required for proper eye size, functions in regulating retinal cell identity and patterning have not yet been examined...
  28. ncbi Zebrafish Hoxb1a regulates multiple downstream genes including prickle1b
    Monica R Rohrschneider
    The Committee on Developmental Biology, The University of Chicago, 1027 East 57th Street, Chicago, IL 60637, USA
    Dev Biol 309:358-72. 2007
    ..Using morpholino knock-down and cell transplantation, we demonstrate that the Hoxb1a target Prickle1b functions cell-autonomously to control facial neuron migration, a single aspect of r4 identity...
  29. pmc Effect of starvation on transcriptomes of brain and liver in adult female zebrafish (Danio rerio)
    Robert E Drew
    Department of Biological Sciences and Initiative for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow
    Physiol Genomics 35:283-95. 2008
    ....
  30. doi Notch-regulated perineurium development from zebrafish spinal cord
    Ho Kim
    Graduate School of Medicine, Korea University, Ansan, Gyeonggido 425 707, Republic of Korea
    Neurosci Lett 448:240-4. 2008
    ..Here we focused on fabp7a, a brain lipid binding protein that is reportedly crucial for the proper differentiation of radial glial progenitor cells...
  31. doi Anatomy of zebrafish cerebellum and screen for mutations affecting its development
    Young Ki Bae
    Laboratory for Vertebrate Axis Formation, RIKEN Center for Developmental Biology, Kobe, Hyogo, Japan
    Dev Biol 330:406-26. 2009
    ..Our data provide a platform for future studies of zebrafish cerebellar development...
  32. pmc FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9
    Virginie Esain
    INSERM, U784, Laboratoire de Génétique Moléculaire du Développement, 46 rue d Ulm, 75230 Paris Cedex 05, France
    Development 137:33-42. 2010
    ..Overall, for the first time in vivo, our results reveal a mechanism of FGF in the control of neural cell diversity...
  33. doi An integrated transcriptomic and proteomic approach characterizing estrogenic and metabolic effects of 17 alpha-ethinylestradiol in zebrafish (Danio rerio)
    Marijke De Wit
    Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Gen Comp Endocrinol 167:190-201. 2010
    ..Overall, this study demonstrated that a proteomics approach can lift the biological interpretation of microarrays to a higher level, and moreover, opens a window for identification of possible new biomarkers...
  34. doi Proneural gene-linked neurogenesis in zebrafish cerebellum
    Shuichi Kani
    Laboratory for Vertebrate Axis Formation, RIKEN Center for Developmental Biology, Kobe, Hyogo, Japan
    Dev Biol 343:1-17. 2010
    ..Our data indicate that proneural gene-linked neurogenesis is evolutionarily conserved in the cerebellum among vertebrates, and that the continuously generated neurons help remodel neural circuits in the adult zebrafish cerebellum...
  35. pmc Evolutionary diversification of the avian fatty acid-binding proteins
    Austin L Hughes
    Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA
    Gene 490:1-5. 2011
    ..other than those of the digestive system, including muscle and the central nervous system (FABP3, FABP4, FABP5, FABP7, and PMP2)...
  36. pmc Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development
    Esther Kur
    Max Delbruck Center for Molecular Medicine, Universitatsmedizin, Berlin, Germany
    Dev Dyn 240:1567-77. 2011
    ....
  37. doi Expression of ventral diencephalon-enriched genes in zebrafish
    Sen Li
    Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai, China
    Dev Dyn 239:3368-79. 2010
    ..related homeobox 1 (Irx1), Kruppel-like factor 7 (Klf7), mab-21-like 1 (Mab21l1), fatty acid binding protein 7 (Fabp7) and stathmin-like 4 (Stmn4), were enriched in the diencephalon of zebrafish...

Research Grants2

  1. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  2. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..