cdh4

Summary

Gene Symbol: cdh4
Description: cadherin 4, type 1, R-cadherin (retinal)
Alias: R-cadherin, rcad, zgc:136316, cadherin-4, cadherin 4, retinal
Species: zebrafish

Top Publications

  1. doi TGFβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway
    Cencan Xing
    State Key Laboratory of Biomembrane and Membrane Engineering, Tsinghua Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China
    J Mol Cell Biol 7:48-61. 2015
  2. ncbi Cadherin-2 function in the cranial ganglia and lateral line system of developing zebrafish
    A E Kerstetter
    Department of Biology, University of Akron, Akron, Ohio 44325 3908, USA
    Dev Dyn 230:137-43. 2004
  3. ncbi Cadherin-4 expression in the zebrafish central nervous system and regulation by ventral midline signaling
    Q Liu
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Brain Res Dev Brain Res 131:17-29. 2001
  4. ncbi Differential expression of cadherin-2 and cadherin-4 in the developing and adult zebrafish visual system
    Q Liu
    Department of Biology, University of Akron, Ohio 44325 3908, USA
    Vis Neurosci 18:923-33. 2001
  5. ncbi Up-regulation of cadherin-2 and cadherin-4 in regenerating visual structures of adult zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, Ohio 44325 3908, USA
    Exp Neurol 177:396-406. 2002
  6. ncbi Cadherin expression in the inner ear of developing zebrafish
    Z M Novince
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Gene Expr Patterns 3:337-9. 2003
  7. ncbi Cadherin-1, -2 and -4 expression in the cranial ganglia and lateral line system of developing zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Gene Expr Patterns 3:653-8. 2003
  8. ncbi Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, Ohio 44325, USA
    Dev Dyn 228:734-9. 2003
  9. ncbi Spatial correspondence between R-cadherin expression domains and retinal ganglion cell axons in developing zebrafish
    Q Liu
    Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor 48109, USA
    J Comp Neurol 410:290-302. 1999
  10. ncbi Cadherin-2 and cadherin-4 in developing, adult and regenerating zebrafish cerebellum
    Q Liu
    Department of Biology, University of Akron, Akron, 185 East Mill Street, Akron, OH 44325 3908, USA
    Brain Res Dev Brain Res 150:63-71. 2004

Scientific Experts

  • Qin Liu
  • Cencan Xing
  • Cho Shuen Hsieh
  • Amy L Wilson
  • James A Marrs
  • Sherry G Babb
  • A E Kerstetter
  • E Azodi
  • J A Marrs
  • Z M Novince
  • Yanchao Han
  • Anming Meng
  • Yixia Wang
  • Shunji Jia
  • Bo Gong
  • Yu Xue
  • Ching Yi Ko
  • Chin Hwa Hu
  • Jian Shiung Wu
  • Chi Kuang Sun
  • Szu Yu Chen
  • Tzu Ming Liu
  • Yu chi Shen
  • Bei Liu
  • Kate F Barald
  • S G Babb-Clendenon
  • Jason Rostedt
  • Bijal Shah
  • Elbert Chen
  • Glen Schmeiser
  • Lauren N Bell
  • Christin Chiappini-Williamson
  • Shannon M Kotradi
  • P A Raymond

Detail Information

Publications17

  1. doi TGFβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway
    Cencan Xing
    State Key Laboratory of Biomembrane and Membrane Engineering, Tsinghua Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China
    J Mol Cell Biol 7:48-61. 2015
    ..Therefore, TGFβ/Smad5 signaling plays an important role in the zebrafish lateral line formation. ..
  2. ncbi Cadherin-2 function in the cranial ganglia and lateral line system of developing zebrafish
    A E Kerstetter
    Department of Biology, University of Akron, Akron, Ohio 44325 3908, USA
    Dev Dyn 230:137-43. 2004
    ..These phenotypes were confirmed by analyzing a cadherin-2 mutant, glass onion. Our results suggest that cadherin-2 function is crucial for the normal formation of the zebrafish lateral line system and a subset of cranial ganglia...
  3. ncbi Cadherin-4 expression in the zebrafish central nervous system and regulation by ventral midline signaling
    Q Liu
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Brain Res Dev Brain Res 131:17-29. 2001
    ..1...
  4. ncbi Differential expression of cadherin-2 and cadherin-4 in the developing and adult zebrafish visual system
    Q Liu
    Department of Biology, University of Akron, Ohio 44325 3908, USA
    Vis Neurosci 18:923-33. 2001
    ..methods, and we compared Cdh2 distribution to that of the previously reported and closely related cadherin-4 (Cdh4, R-cadherin)...
  5. ncbi Up-regulation of cadherin-2 and cadherin-4 in regenerating visual structures of adult zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, Ohio 44325 3908, USA
    Exp Neurol 177:396-406. 2002
    ..In this study, we examined expression of zebrafish cadherin-2 (Cdh2, N-cadherin) and cadherin-4 (Cdh4, R-cadherin) in the visual system of adult zebrafish after eye or optic nerve lesions using immunocytochemistry and ..
  6. ncbi Cadherin expression in the inner ear of developing zebrafish
    Z M Novince
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Gene Expr Patterns 3:337-9. 2003
    ..In contrast, cadherin-11mRNA was widely expressed earlier in the otic placode, and later became restricted to a subset of cells in the inner ear, including hair cells...
  7. ncbi Cadherin-1, -2 and -4 expression in the cranial ganglia and lateral line system of developing zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Gene Expr Patterns 3:653-8. 2003
    ....
  8. ncbi Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish
    Q Liu
    Department of Biology, University of Akron, Akron, Ohio 44325, USA
    Dev Dyn 228:734-9. 2003
    ....
  9. ncbi Spatial correspondence between R-cadherin expression domains and retinal ganglion cell axons in developing zebrafish
    Q Liu
    Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor 48109, USA
    J Comp Neurol 410:290-302. 1999
    ..These results demonstrate that R-cadherin is appropriately distributed to play a role in regulating development of the zebrafish visual system, and in particular, pathfinding and synaptogenesis of retinal ganglion cell axons...
  10. ncbi Cadherin-2 and cadherin-4 in developing, adult and regenerating zebrafish cerebellum
    Q Liu
    Department of Biology, University of Akron, Akron, 185 East Mill Street, Akron, OH 44325 3908, USA
    Brain Res Dev Brain Res 150:63-71. 2004
    ..Our results suggest that cadherins are crucial for the normal development of the zebrafish cerebellum, and they may also be involved in the regeneration of injured fish cerebellum...
  11. ncbi Differential expression of cadherins in the developing and adult zebrafish olfactory system
    Qin Liu
    Department of Biology, University of Akron, Akron, Ohio 44325 3908, USA
    J Comp Neurol 478:269-81. 2004
    ..We hypothesize that the differential expression of these three cadherins in the developing zebrafish major olfactory structures reflects functionally different roles in the development of the vertebrate olfactory system...
  12. ncbi Zebrafish R-cadherin (Cdh4) controls visual system development and differentiation
    Sherry G Babb
    Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana 56202 5130, USA
    Dev Dyn 233:930-45. 2005
    In zebrafish, R-cadherin (cadherin-4 or Cdh4) is expressed in the retina and in retinorecipient brain regions, suggesting that Cdh4 functions during visual system development...
  13. pmc Expression of cadherin10, a type II classic cadherin gene, in the nervous system of the embryonic zebrafish
    Qin Liu
    Department of Biology, University of Akron, OH, USA
    Gene Expr Patterns 6:703-10. 2006
    ..Our results show that cdh10 expression in the zebrafish developing nervous system is both spatially and temporally regulated...
  14. pmc Differential expression of photoreceptor-specific genes in the retina of a zebrafish cadherin2 mutant glass onion and zebrafish cadherin4 morphants
    Q Liu
    Department of Biology, University of Akron, 302 Buchtel Common, Akron, OH 44325, USA
    Exp Eye Res 84:163-75. 2007
    ..Our results suggest that cadherin2 and cadherin4 play important roles in the differentiation of zebrafish retinal photoreceptors...
  15. pmc Cadherin-4 plays a role in the development of zebrafish cranial ganglia and lateral line system
    Amy L Wilson
    Department of Biology, University of Akron, Akron, OH 44325 3908, USA
    Dev Dyn 236:893-902. 2007
    ..Cadherin-4 (Cdh4) function in the formation of these structures in zebrafish was studied using morpholino antisense technology...
  16. doi In vivo long-term continuous observation of gene expression in zebrafish embryo nerve systems by using harmonic generation microscopy and morphant technology
    Cho Shuen Hsieh
    National Taiwan University, Department of Electrical Engineering, and, Graduate Institute of Photonics and Optoelectronics, Taipei 10617, Taiwan
    J Biomed Opt 13:064041. 2008
    ..e., SHG microscopy and THG microscopy, successfully revealed the weak cell adhesion, cell apoptosis, nerve formation reduction, and neural tube distortion in the morphant zebrafish embryos...
  17. ncbi R-cadherin expression in the developing and adult zebrafish visual system
    Q Liu
    Department of Anatomy and Cell Biology, 4610 Medical Science II, University of Michigan, Ann Arbor 48109, USA
    J Comp Neurol 410:303-19. 1999
    ..These results suggest that R-cadherin-mediated adhesion plays a role in development and maintenance of neuronal connections in zebrafish visual system...