Gene Symbol: ail
Description: attachment invasion locus protein
Species: Yersinia pestis CO92
- Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipidsLeigh A Plesniak
Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
Biochim Biophys Acta 1808:482-9. 2011b>Ail is an outer membrane protein and virulence factor of Yersinia pestis, an extremely pathogenic, category A biothreat agent, responsible for precipitating massive human plague pandemics throughout history...
- Structural insights into Ail-mediated adhesion in Yersinia pestisSatoshi Yamashita
Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
Structure 19:1672-82. 2011b>Ail is an outer membrane protein from Yersinia pestis that is highly expressed in a rodent model of bubonic plague, making it a good candidate for vaccine development...
- Differential contribution of tryptophans to the folding and stability of the attachment invasion locus transmembrane β-barrel from Yersinia pestisAnkit Gupta
1 Molecular Biophysics Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal India 2
Sci Rep 4:6508. 2014Attachment invasion locus (Ail) protein of Yersinia pestis is a crucial outer membrane protein for host invasion and determines bacterial survival within the host...
- Influence of the lipid membrane environment on structure and activity of the outer membrane protein Ail from Yersinia pestisYi Ding
Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
Biochim Biophys Acta 1848:712-20. 2015..Here we describe how the sample environment affects the activity of the outer membrane protein Ail (attachment invasion locus) from Yersinia pestis...
- Combinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plagueBethany L Tiner
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA
Infect Immun 83:1318-38. 2015..Here, we deleted the ail gene (encoding the attachment-invasion locus) from wild-type (WT) strain CO92 or its lpp single and Δlpp ΔmsbB ..
- Role of the Yersinia pestis Ail protein in preventing a protective polymorphonuclear leukocyte response during bubonic plagueB Joseph Hinnebusch
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA
Infect Immun 79:4984-9. 2011..In this study, we examined the effect of Ail, a 17-kDa outer membrane protein that protects Y...