DREB1A

Summary

Gene Symbol: DREB1A
Description: dehydration response element B1A
Alias: ATCBF3, C-REPEAT BINDING FACTOR 3, C-REPEAT BINDING FACTOR 3, CBF3, T30C3.3, TRANSCRIPTIONAL ACTIVATOR CBF3, dehydration response element B1A
Species: thale cress

Top Publications

  1. pmc Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis
    Q Liu
    Biological Resources Division, Japan International Research Center for Agricultural Sciences JIRCAS, Ministry of Agriculture, Forestry, and Fisheries, 2 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 10:1391-406. 1998
  2. doi Lipophilic components of the brown seaweed, Ascophyllum nodosum, enhance freezing tolerance in Arabidopsis thaliana
    Prasanth Rayirath
    Department of Plant and Animal Sciences, Nova Scotia Agricultural College, 58 River Road, P O Box 550, Truro, NS B2N5E3, Canada
    Planta 230:135-47. 2009
  3. doi Molecular, anatomical and physiological properties of a genetically modified soybean line transformed with rd29A:AtDREB1A for the improvement of drought tolerance
    A M Polizel
    Departamento de Genetica, Universidade Estadual de Londrina, Londrina, PR, Brasil
    Genet Mol Res 10:3641-56. 2011
  4. pmc Arabidopsis CBF1 and CBF3 have a different function than CBF2 in cold acclimation and define different gene classes in the CBF regulon
    Fernando Novillo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, Carretera de La Coruna, Km 7, 28040 Madrid, Spain
    Proc Natl Acad Sci U S A 104:21002-7. 2007
  5. pmc Low temperature induction of Arabidopsis CBF1, 2, and 3 is gated by the circadian clock
    Sarah G Fowler
    Michigan State University U S Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 137:961-8. 2005
  6. pmc Arabidopsis CBF3/DREB1A and ABF3 in transgenic rice increased tolerance to abiotic stress without stunting growth
    Se Jun Oh
    Division of Bioscience and Bioinformatics, Myongji University, Yongin 449 728, Korea
    Plant Physiol 138:341-51. 2005
  7. pmc Functional analysis of an Arabidopsis transcription factor, DREB2A, involved in drought-responsive gene expression
    Yoh Sakuma
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 18:1292-309. 2006
  8. doi RDM4 modulates cold stress resistance in Arabidopsis partially through the CBF-mediated pathway
    Zhulong Chan
    Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei Province, 430074, China
    New Phytol 209:1527-39. 2016
  9. pmc DREB2C interacts with ABF2, a bZIP protein regulating abscisic acid-responsive gene expression, and its overexpression affects abscisic acid sensitivity
    Sun ji Lee
    Department of Molecular Biotechnology and Kumho Life Science Laboratory, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 500 757, South Korea
    Plant Physiol 153:716-27. 2010
  10. doi Natural variation of C-repeat-binding factor (CBFs) genes is a major cause of divergence in freezing tolerance among a group of Arabidopsis thaliana populations along the Yangtze River in China
    Juqing Kang
    State Key Laboratory for Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China
    New Phytol 199:1069-80. 2013

Patents

  1. Production of plants having improved rooting efficiency and vase life using stress-resistance gene

Scientific Experts

  • Yen Heng Lin
  • Kyonoshin Maruyama
  • Kazuko Yamaguchi-Shinozaki
  • Yoh Sakuma
  • Kazuo Shinozaki
  • K Yamaguchi-Shinozaki
  • Motoaki Seki
  • Zhulong Chan
  • Ye Seul Kim
  • Malia A Gehan
  • Krithika Anbazhagan
  • Haiou Dou
  • G Ravikumar
  • Faxiang Wan
  • Liyuan Chen
  • Juqing Kang
  • Yanru Hu
  • M Kasuga
  • M Akhtar
  • Haicui Suo
  • Hesham Oraby
  • A M Polizel
  • Michael F Thomashow
  • Sun ji Lee
  • Eunjoo Seo
  • Prasanth Rayirath
  • K Shinozaki
  • Soo Young Kim
  • Babak Behnam
  • Kenji Miura
  • Fernando Novillo
  • Mie Kasuga
  • Miki Fujita
  • Chantal Vergnolle
  • M Seki
  • Sarah G Fowler
  • Se Jun Oh
  • K Nakashima
  • Zixin Mu
  • Yuanlei Hu
  • Minjie Cao
  • Yanping Wang
  • Xin Jian He
  • Xin Deng
  • Haiqing Wang
  • Jian Kang Zhu
  • Yuehua Gong
  • Qingwei Meng
  • Kiran K Sharma
  • Sunchung Park
  • Vincent Vadez
  • Kunpeng Xv
  • Srinivas Reddy Dumbala
  • Chuanfu An
  • Hyo Jun Lee
  • Pooja Bhatnagar-Mathur
  • Sarah J Gilmour
  • Jae Hyung Lee
  • Gang Li
  • Chung Mo Park
  • S Miura
  • Minyoung Lee
  • P B Kavi Kishor
  • Xinghong Yang
  • Chin Mei Lee
  • Q Liu
  • R M Sundaram
  • S M Balachandran
  • Xingguo Zhang
  • Yu Pan
  • Yanglu Pan
  • Jinghua Li
  • Xiangfu Chen
  • P Manimaran
  • Yongqing Wang
  • K C Bansal
  • S R Voleti
  • B C Viraktamath
  • D Subrahmanyam
  • Shibing Tian
  • Sanja Roje
  • Yihua Zhou
  • Huiting Zhang
  • Takayuki Tohge
  • Yihao Shi
  • Henriette Weber
  • Hongya Gu
  • Tianshu Sun
  • Liqun Jiang
  • Fang Wang

Detail Information

Publications32

  1. pmc Two transcription factors, DREB1 and DREB2, with an EREBP/AP2 DNA binding domain separate two cellular signal transduction pathways in drought- and low-temperature-responsive gene expression, respectively, in Arabidopsis
    Q Liu
    Biological Resources Division, Japan International Research Center for Agricultural Sciences JIRCAS, Ministry of Agriculture, Forestry, and Fisheries, 2 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 10:1391-406. 1998
    ..Two cDNA clones that encode DRE binding proteins, DREB1A and DREB2A, were isolated by using the yeast one-hybrid screening technique...
  2. doi Lipophilic components of the brown seaweed, Ascophyllum nodosum, enhance freezing tolerance in Arabidopsis thaliana
    Prasanth Rayirath
    Department of Plant and Animal Sciences, Nova Scotia Agricultural College, 58 River Road, P O Box 550, Truro, NS B2N5E3, Canada
    Planta 230:135-47. 2009
    ..Further, the A. nodosum extract treatment modulated the expression of the cold response genes, COR15A, RD29A, and CBF3, resulting in enhanced tolerance to freezing temperatures. More than 2.6-fold increase in expression of RD29A, 1...
  3. doi Molecular, anatomical and physiological properties of a genetically modified soybean line transformed with rd29A:AtDREB1A for the improvement of drought tolerance
    A M Polizel
    Departamento de Genetica, Universidade Estadual de Londrina, Londrina, PR, Brasil
    Genet Mol Res 10:3641-56. 2011
    ..This construct expressed dehydration- responsive element binding protein DREB1A from the stress-inducible rd29A promoter...
  4. pmc Arabidopsis CBF1 and CBF3 have a different function than CBF2 in cold acclimation and define different gene classes in the CBF regulon
    Fernando Novillo
    Departamento de Biotecnologia, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria, Carretera de La Coruna, Km 7, 28040 Madrid, Spain
    Proc Natl Acad Sci U S A 104:21002-7. 2007
    ..proteins constitute a small family of Arabidopsis transcriptional activators (CBF1/DREB1B, CBF2/DREB1C, and CBF3/DREB1A) that play a prominent role in cold acclimation...
  5. pmc Low temperature induction of Arabidopsis CBF1, 2, and 3 is gated by the circadian clock
    Sarah G Fowler
    Michigan State University U S Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Physiol 137:961-8. 2005
    ..Recently, it has been shown that basal levels of CBF3 transcripts and those of certain CBF-regulated genes exhibit circadian cycling...
  6. pmc Arabidopsis CBF3/DREB1A and ABF3 in transgenic rice increased tolerance to abiotic stress without stunting growth
    Se Jun Oh
    Division of Bioscience and Bioinformatics, Myongji University, Yongin 449 728, Korea
    Plant Physiol 138:341-51. 2005
    ..in comparison with that of Arabidopsis, we developed transgenic rice plants that constitutively expressed CBF3/DREB1A (CBF3) and ABF3, Arabidopsis genes that function in abscisic acid-independent and abscisic acid-dependent stress-..
  7. pmc Functional analysis of an Arabidopsis transcription factor, DREB2A, involved in drought-responsive gene expression
    Yoh Sakuma
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 18:1292-309. 2006
    Transcription factors DREB1A/CBF3 and DREB2A specifically interact with cis-acting dehydration-responsive element/C-repeat (DRE/CRT) involved in cold and drought stress-responsive gene expression in Arabidopsis thaliana...
  8. doi RDM4 modulates cold stress resistance in Arabidopsis partially through the CBF-mediated pathway
    Zhulong Chan
    Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei Province, 430074, China
    New Phytol 209:1527-39. 2016
    ..immunoprecipitation results suggested that RDM4 is important for Pol II occupancy at the promoters of CBF2 and CBF3. We present evidence of a considerable role for RDM4 in regulating gene expression at low temperature, including ..
  9. pmc DREB2C interacts with ABF2, a bZIP protein regulating abscisic acid-responsive gene expression, and its overexpression affects abscisic acid sensitivity
    Sun ji Lee
    Department of Molecular Biotechnology and Kumho Life Science Laboratory, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 500 757, South Korea
    Plant Physiol 153:716-27. 2010
    ..We further show that other AP2 domain proteins, DREB1A and DREB2A, interact with ABF2 and that other ABF family members, ABF3 and ABF4, interact with DREB2C...
  10. doi Natural variation of C-repeat-binding factor (CBFs) genes is a major cause of divergence in freezing tolerance among a group of Arabidopsis thaliana populations along the Yangtze River in China
    Juqing Kang
    State Key Laboratory for Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China
    New Phytol 199:1069-80. 2013
    ..The CBF2 in SXcgx experienced a stronger natural selection in the cooler environment after CBF3 lost its response to low temperature, which possibly reflects a local adaptation of these populations during the ..
  11. pmc Jasmonate regulates the inducer of cbf expression-C-repeat binding factor/DRE binding factor1 cascade and freezing tolerance in Arabidopsis
    Yanru Hu
    Key Laboratory of Tropical Forest Ecology, Xishuangbana Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, Yunan 650223, China
    Plant Cell 25:2907-24. 2013
    ..Taken together, our study provides evidence that jasmonate functions as a critical upstream signal of the ICE-CBF/DREB1 pathway to positively regulate Arabidopsis freezing tolerance...
  12. pmc Stress-inducible expression of AtDREB1A transcription factor greatly improves drought stress tolerance in transgenic indica rice
    G Ravikumar
    Directorate of Rice Research, Rajendranagar, Hyderabad, 500 030, India
    Transgenic Res 23:421-39. 2014
    ..The transcription factor DREB1A, identified from the model plant Arabidopsis thaliana, has been reported to enhance stress tolerance against ..
  13. doi Potato plants ectopically expressing Arabidopsis thaliana CBF3 exhibit enhanced tolerance to high-temperature stress
    Haiou Dou
    State Key Laboratory of Crop Biology, Shandong Key Laboratory of Crop Biology, Shandong Agricultural University, Taian, 271018, China
    Plant Cell Environ 38:61-72. 2015
    ..Our results revealed that temperature of 40 °C or higher can significantly induce AtCBF3 expression...
  14. doi Heterologous expression of Arabidopsis C-repeat binding factor 3 (AtCBF3) and cold-regulated 15A (AtCOR15A) enhanced chilling tolerance in transgenic eggplant (Solanum melongena L.)
    Faxiang Wan
    Key Laboratory of Horticulture Science for Southern Mountainous Regions Chinese Ministry of Education, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, 400715, People s Republic of China
    Plant Cell Rep 33:1951-61. 2014
    Our study shows that the expression of AtCBF3 and AtCOR15A improved the chilling tolerance in transgenic eggplant...
  15. doi DREB1A overexpression in transgenic chickpea alters key traits influencing plant water budget across water regimes
    Krithika Anbazhagan
    International Crops Research Institute for the Semi Arid Tropics ICRISAT, Patancheru, Telangana, 502324, India
    Plant Cell Rep 34:199-210. 2015
    We demonstrate the role of DREB1A transcription factor in better root and shoot partitioning and higher transpiration efficiency in transgenic chickpea under drought stress Chickpea (Cicer arietinum L...
  16. doi The unified ICE-CBF pathway provides a transcriptional feedback control of freezing tolerance during cold acclimation in Arabidopsis
    Ye Seul Kim
    Department of Chemistry, Seoul National University, Seoul, 151 742, Korea
    Plant Mol Biol 89:187-201. 2015
    ..Inducer of CBF expression 1 (ICE1) plays a key role by activating CBF3 expression in shaping the cold-induced transcriptome...
  17. doi Natural variation in the C-repeat binding factor cold response pathway correlates with local adaptation of Arabidopsis ecotypes
    Malia A Gehan
    MSU DOE Plant Research Laboratory, Michigan State University, East Lansing, MI, 48824, USA
    Plant J 84:682-93. 2015
    ..The CBF locus includes three genes - CBF1, CBF2 and CBF3 - that are induced by low temperature and encode transcription factors that regulate a group of more than 100 genes,..
  18. pmc Arabidopsis BPM proteins function as substrate adaptors to a cullin3-based E3 ligase to affect fatty acid metabolism in plants
    Liyuan Chen
    School of Biological Sciences, Washington State University, Pullman, Washington 99164, USA
    Plant Cell 25:2253-64. 2013
    ..Overall, this work demonstrates a link between fatty acid metabolism and E3 ligase activities in plants and establishes CUL3-based E3 ligases as key regulators in transcriptional processes that involve ERF/AP2 family members...
  19. ncbi DREB1/CBF transcription factors: their structure, function and role in abiotic stress tolerance in plants
    M Akhtar
    Department of Genetics and Plant Breeding, Govind Ballabh Pant University of Agriculture and Technology, Pantnagar 263 145, India
    J Genet 91:385-95. 2012
    ..The recent progress related to genetic engineering of DREB1/CBF transcription factors in various crops and model plants is also summarized...
  20. pmc Overexpression of AtDREB1A causes a severe dwarf phenotype by decreasing endogenous gibberellin levels in soybean [Glycine max (L.) Merr]
    Haicui Suo
    The Guangdong Subcenter of National Center for Soybean Improvement, State Key Laboratory of Agricultural and Biological Resources Protection and Utilization in Subtropics, College of Agriculture, South China Agricultural University, Guangzhou, Guangdong, P R China
    PLoS ONE 7:e45568. 2012
    ..In this study, the Arabidopsis DREB1A gene driven by the CaMV 35S promoter was introduced into soybean plants by Agrobacterium- mediated transformation...
  21. doi Physiological and biochemical changes of CBF3 transgenic oat in response to salinity stress
    Hesham Oraby
    Department of Plant Science, Laval University, Quebec, QC, Canada
    Plant Sci 185:331-9. 2012
    ..The impact of introducing the Arabidopsis CBF3 gene controlled by the rd29A stress-inducible promoter in T(2) transgenic oat on salinity tolerance and associated ..
  22. pmc Crosstalk between cold response and flowering in Arabidopsis is mediated through the flowering-time gene SOC1 and its upstream negative regulator FLC
    Eunjoo Seo
    National Research Laboratory of Plant Developmental Genetics, School of Biological Sciences, Seoul National University, Seoul 151 742, Korea
    Plant Cell 21:3185-97. 2009
    ....
  23. pmc Metabolic pathways involved in cold acclimation identified by integrated analysis of metabolites and transcripts regulated by DREB1A and DREB2A
    Kyonoshin Maruyama
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    Plant Physiol 150:1972-80. 2009
    b>DREB1A/CBF3 and DREB2A are transcription factors that specifically interact with a cis-acting dehydration-responsive element (DRE), which is involved in cold- and dehydration-responsive gene expression in Arabidopsis (Arabidopsis thaliana)..
  24. pmc Molecular population genetics and gene expression analysis of duplicated CBF genes of Arabidopsis thaliana
    Yen Heng Lin
    Institute of Plant Biology, National Taiwan University, Taipei 10617, Taiwan
    BMC Plant Biol 8:111. 2008
    ..CBF/DREB duplicate genes are widely distributed in higher plants and encode transcriptional factors, or CBFs, which bind a DNA regulatory element and impart responsiveness to low temperatures and dehydration...
  25. ncbi Arabidopsis rd29A::DREB1A enhances freezing tolerance in transgenic potato
    Babak Behnam
    Gene Research Center, Graduate School of Life and Environmental Sciences, University of Tsukuba, Ten nodai 1 1 1, Ibaraki, Tsukuba 305 8752, Japan
    Plant Cell Rep 26:1275-82. 2007
    ..The lines were transgenic for the DREB1A gene under control of the rd29A promoter, both of which were derived from Arabidopsis thaliana...
  26. pmc SIZ1-mediated sumoylation of ICE1 controls CBF3/DREB1A expression and freezing tolerance in Arabidopsis
    Kenji Miura
    Center for Plant Environmental Stress Physiology, Purdue University, West Lafayette, Indiana 47907 2010, USA
    Plant Cell 19:1403-14. 2007
    ..Cold-induced expression of CBF/DREB1, particularly of CBF3/DREB1A, and of the regulon genes was repressed by siz1...
  27. pmc The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions
    Chantal Vergnolle
    Laboratoire de Physiologie Cellulaire et Moleculaire des Plantes, Formation de Recherche en Evolution 2846, Centre National de la Recherche Scientifique Université Pierre et Marie Curie, F 94200 Ivry sur Seine, France
    Plant Physiol 139:1217-33. 2005
    ..The connection of these pathways with the CBF pathway, currently the most understood genetic system playing a role in cold acclimation, is discussed...
  28. ncbi Identification of cold-inducible downstream genes of the Arabidopsis DREB1A/CBF3 transcriptional factor using two microarray systems
    Kyonoshin Maruyama
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, 1 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
    Plant J 38:982-93. 2004
    ..Transgenic plants overexpressing DREB1A showed activated expression of many stress-inducible genes and improved tolerance to not only drought, salinity, ..
  29. ncbi Monitoring the expression profiles of 7000 Arabidopsis genes under drought, cold and high-salinity stresses using a full-length cDNA microarray
    Motoaki Seki
    Plant Mutation Exploration Team, Plant Functional Genomics Research Group, RIKEN Genomic Sciences Center, 3 1 1 Koyadai, Tsukuba 305 0074, Japan
    Plant J 31:279-92. 2002
    ..The cold-inducible genes were classified into at least two gene groups from their expression profiles. DREB1A was included in a group whose expression peaked at 2 h after cold treatment...
  30. pmc Monitoring the expression pattern of 1300 Arabidopsis genes under drought and cold stresses by using a full-length cDNA microarray
    M Seki
    Plant Mutation Exploration Team, Plant Functional Genomics Research Group, RIKEN Genomic Sciences Center, 3 1 1 Koyadai, Tsukuba 305 0074, Japan
    Plant Cell 13:61-72. 2001
    ..approximately 1300 full-length Arabidopsis cDNAs to identify drought- and cold-inducible genes and target genes of DREB1A/CBF3, a transcription factor that controls stress-inducible gene expression...
  31. ncbi Improving plant drought, salt, and freezing tolerance by gene transfer of a single stress-inducible transcription factor
    M Kasuga
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Ministry of Agriculture, Forestry and Fisheries, Tsukuba, Ibaraki
    Nat Biotechnol 17:287-91. 1999
    ..The transcription factor DREB1A specifically interacts with the DRE and induces expression of stress tolerance genes...
  32. ncbi An Arabidopsis gene family encoding DRE/CRT binding proteins involved in low-temperature-responsive gene expression
    Z K Shinwari
    Biological Resources Division, Japan International Research Center for Agricultural Sciences JIRCAS, 1 2, Ohwashi, Ibaraki, Tsukuba, 305 8686, Japan
    Biochem Biophys Res Commun 250:161-70. 1998
    ..from the cold stress signal to gene expression, we characterized a gene family for DRE/CRT-binding proteins DREB1A and CBF1 in Arabidopsis thaliana...

Patents1

  1. Production of plants having improved rooting efficiency and vase life using stress-resistance gene
    Patent Number: EP1457564-A2; Date:2004-09-15