Genomes and Genes
Gene Symbol: pbp2
Description: penicillin-binding protein 2
Species: Staphylococcus aureus subsp. aureus COL
- Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistanceC J Hackbarth
Division of Infectious Diseases, San Francisco General Hospital, California 94110
Antimicrob Agents Chemother 39:103-6. 1995..These structural and biochemical changes may contribute to the strains' resistance to beta-lactam antibiotics...
- Nucleotide sequence of the structural gene for the penicillin-binding protein 2 of Staphylococcus aureus and the presence of a homologous gene in other staphylococciK Murakami
Kanzakigawa Laboratory, Shionogi and Co, Ltd, Osaka, Japan
FEMS Microbiol Lett 117:131-6. 1994The structural gene for penicillin-binding protein 2 (PBP2) of Staphylococcus aureus was cloned and sequenced...
- Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 geneM G Pinho
Laboratory of Microbiology, The Rockefeller University, New York, New York 10021, USA
J Bacteriol 180:6077-81. 1998Sequencing of the vicinity of the staphylococcal pbp2 gene and transcriptional analysis by primer extension and promoter fusions were used to show that pbp2 is part of an operon that also includes a gene with high homology to prfA of ..
- Transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus by cell wall-active antibiotics oxacillin and vancomycinSusan Boyle-Vavra
Department of Pediatrics, The University of Chicago, Illinois 60637, USA
Antimicrob Agents Chemother 47:1028-36. 2003..These data support the idea that pbpB expression is modulated by a trans-acting factor in response to the presence of the cell wall-active antibiotics vancomycin and oxacillin...