pbp2

Summary

Gene Symbol: pbp2
Description: penicillin-binding protein 2
Species: Staphylococcus aureus subsp. aureus COL

Top Publications

  1. pmc Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance
    C J Hackbarth
    Division of Infectious Diseases, San Francisco General Hospital, California 94110
    Antimicrob Agents Chemother 39:103-6. 1995
  2. ncbi Nucleotide sequence of the structural gene for the penicillin-binding protein 2 of Staphylococcus aureus and the presence of a homologous gene in other staphylococci
    K Murakami
    Kanzakigawa Laboratory, Shionogi and Co, Ltd, Osaka, Japan
    FEMS Microbiol Lett 117:131-6. 1994
  3. pmc Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 gene
    M G Pinho
    Laboratory of Microbiology, The Rockefeller University, New York, New York 10021, USA
    J Bacteriol 180:6077-81. 1998
  4. pmc Transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus by cell wall-active antibiotics oxacillin and vancomycin
    Susan Boyle-Vavra
    Department of Pediatrics, The University of Chicago, Illinois 60637, USA
    Antimicrob Agents Chemother 47:1028-36. 2003

Scientific Experts

  • Susan Boyle-Vavra
  • M G Pinho
  • C J Hackbarth
  • H de Lencastre
  • A Tomasz
  • K Murakami
  • T Kocagoz
  • S Kocagoz
  • H F Chambers
  • T Fujimura
  • M Doi

Detail Information

Publications4

  1. pmc Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance
    C J Hackbarth
    Division of Infectious Diseases, San Francisco General Hospital, California 94110
    Antimicrob Agents Chemother 39:103-6. 1995
    ..These structural and biochemical changes may contribute to the strains' resistance to beta-lactam antibiotics...
  2. ncbi Nucleotide sequence of the structural gene for the penicillin-binding protein 2 of Staphylococcus aureus and the presence of a homologous gene in other staphylococci
    K Murakami
    Kanzakigawa Laboratory, Shionogi and Co, Ltd, Osaka, Japan
    FEMS Microbiol Lett 117:131-6. 1994
    The structural gene for penicillin-binding protein 2 (PBP2) of Staphylococcus aureus was cloned and sequenced...
  3. pmc Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 gene
    M G Pinho
    Laboratory of Microbiology, The Rockefeller University, New York, New York 10021, USA
    J Bacteriol 180:6077-81. 1998
    Sequencing of the vicinity of the staphylococcal pbp2 gene and transcriptional analysis by primer extension and promoter fusions were used to show that pbp2 is part of an operon that also includes a gene with high homology to prfA of ..
  4. pmc Transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus by cell wall-active antibiotics oxacillin and vancomycin
    Susan Boyle-Vavra
    Department of Pediatrics, The University of Chicago, Illinois 60637, USA
    Antimicrob Agents Chemother 47:1028-36. 2003
    ..These data support the idea that pbpB expression is modulated by a trans-acting factor in response to the presence of the cell wall-active antibiotics vancomycin and oxacillin...