pol

Summary

Gene Symbol: pol
Description: protease, RT, RNaseH, integrase
Alias: protease, RT, RNaseH, integrase, pol protein
Species: Simian immunodeficiency virus SIV-mnd 2

Top Publications

  1. doi High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo
    Sarah B Lloyd
    Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria 3010, Australia
    Virology 492:1-10. 2016
  2. ncbi Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus
    J Takehisa
    Department of Viral Infection and International Health, Graduate School of Medical Science, Kanazawa University, Kanazawa 920 8640, Japan
    AIDS Res Hum Retroviruses 17:1143-54. 2001

Scientific Experts

  • Sarah B Lloyd
  • Gilda Tachedjian
  • Robert De Rose
  • Thakshila H Amarasena
  • Sheilajen Alcantara
  • Miles P Davenport
  • Vanessa Venturi
  • Marit Lichtfuss
  • Hamid Alinejad-Rokny
  • Stephen J Kent
  • Wendy R Winnall
  • J Takehisa
  • T Shimada
  • M Ikeda
  • Y Taniguchi
  • C Ngansop
  • I Mboudjeka
  • K Ibuki
  • N Ndembi
  • H Ichimura
  • S Kuate
  • L Zekeng
  • T Miura
  • Y Harada
  • M Hayami
  • B Bikandou
  • L Kaptue
  • Y Yamaguchi-Kabata

Detail Information

Publications2

  1. doi High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo
    Sarah B Lloyd
    Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Victoria 3010, Australia
    Virology 492:1-10. 2016
    ..Thus, we showed that RT mutants, and specifically the common K65R drug-resistance mutation, had impaired replication capacity and higher fidelity. These results have implications for the pathogenesis of drug-resistant HIV. ..
  2. ncbi Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus
    J Takehisa
    Department of Viral Infection and International Health, Graduate School of Medical Science, Kanazawa University, Kanazawa 920 8640, Japan
    AIDS Res Hum Retroviruses 17:1143-54. 2001
    ..A phylogenetic analysis based on the pol sequence showed that the newly found SIVs from Cameroonian mandrills did not cluster with SIVmndGB1, which is the ..