Genomes and Genes
Gene Symbol: IL1R2
Description: interleukin 1 receptor type 2
Alias: interleukin-1 receptor type 2, soluble type II IL-1 receptor
Species: Rhesus monkey
- The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 actionDirk E Smith
Amgen Corporation, 51 University Street, Seattle, WA 98101, USA
Immunity 18:87-96. 2003..These findings suggest that the soluble form of IL-1R AcP contributes to the antagonism of IL-1 action by the type II decoy receptor, adding another layer of complexity to the regulation of IL-1 action...
- A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptorDirk E Smith
Amgen Corporation, Seattle, Washington 98101, USA
J Biol Chem 277:47619-25. 2002..Structural and mutational analysis revealed that the unique sIL1R-II binding ability of human IL-1beta is due to a single amino acid difference compared with monkey IL-1beta...