Pofut1

Summary

Gene Symbol: Pofut1
Description: protein O-fucosyltransferase 1
Alias: Fut12, GDP-fucose protein O-fucosyltransferase 1, O-FucT-1, peptide-O-fucosyltransferase 1, pofut1 {ECO:0000312, RGD:1303001}
Species: rat

Top Publications

  1. ncbi A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs
    Ivan Martinez-Duncker
    Unité de Glycobiologie et Signalisation Cellulaire, INSERM U504, GDR CNRS 2590, Universite de Paris Sud XI, 16 Ave Paul Vaillant Couturier, 94807 Villejuif Cedex France
    Glycobiology 13:1C-5C. 2003
  2. ncbi Glycosylation regulates Notch signalling
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Nat Rev Mol Cell Biol 4:786-97. 2003
  3. ncbi O-fucosylation of notch occurs in the endoplasmic reticulum
    Yi Luo
    Department of Biochemistry and Cell Biology, Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    J Biol Chem 280:11289-94. 2005
  4. ncbi Cell and molecular biology of Notch
    Ulla Maj Fiuza
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    J Endocrinol 194:459-74. 2007

Scientific Experts

  • Ulla Maj Fiuza
  • Yi Luo
  • Nicola Haines
  • Ivan Martinez-Duncker
  • Robert S Haltiwanger
  • Rafael Oriol
  • Jean Jacques Candelier
  • Rosella Mollicone
  • Kenneth D Irvine
  • Christelle Breton

Detail Information

Publications4

  1. ncbi A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs
    Ivan Martinez-Duncker
    Unité de Glycobiologie et Signalisation Cellulaire, INSERM U504, GDR CNRS 2590, Universite de Paris Sud XI, 16 Ave Paul Vaillant Couturier, 94807 Villejuif Cedex France
    Glycobiology 13:1C-5C. 2003
    ..shared by alpha2-fucosyltransferases, alpha6-fucosyltransferases, the protein-O-fucosyltransferase family 1 (POFUT1) and a newly identified protein-O-fucosyltransferase family 2 (POFUT2), together with evidence that the present ..
  2. ncbi Glycosylation regulates Notch signalling
    Nicola Haines
    Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Nat Rev Mol Cell Biol 4:786-97. 2003
    ....
  3. ncbi O-fucosylation of notch occurs in the endoplasmic reticulum
    Yi Luo
    Department of Biochemistry and Cell Biology, Institute for Cell and Developmental Biology, State University of New York at Stony Brook, Stony Brook, New York 11794 5215, USA
    J Biol Chem 280:11289-94. 2005
    ..The fact that O-FucT-1 recognizes properly folded epidermal growth factor-like repeats, together with this unique localization, suggests that it may play a role in quality control...
  4. ncbi Cell and molecular biology of Notch
    Ulla Maj Fiuza
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    J Endocrinol 194:459-74. 2007
    ..In this review, we will describe the multiple roles of Notch and how various factors can regulate Notch signalling...