otx

Summary

Gene Symbol: otx
Description: orthodenticle-related protein
Alias: homeobox protein OTX, orthodenticle homolog, spOTX
Species: purple sea urchin

Top Publications

  1. ncbi An orthodenticle-related protein from Strongylocentrotus purpuratus
    L Gan
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030
    Dev Biol 167:517-28. 1995
  2. ncbi Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene
    C A Mao
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030
    Dev Biol 165:229-42. 1994
  3. ncbi Transient appearance of Strongylocentrotus purpuratus Otx in micromere nuclei: cytoplasmic retention of SpOtx possibly mediated through an alpha-actinin interaction
    C K Chuang
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Dev Genet 19:231-7. 1996
  4. ncbi Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus
    X Li
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Dev Biol 187:253-66. 1997
  5. ncbi Correct Expression of spec2a in the sea urchin embryo requires both Otx and other cis-regulatory elements
    C H Yuh
    Division of Biology, California Institute of Biology, Pasadena, California 91125, USA
    Dev Biol 232:424-38. 2001
  6. ncbi An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network
    Chiou Hwa Yuh
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 269:536-51. 2004

Detail Information

Publications6

  1. ncbi An orthodenticle-related protein from Strongylocentrotus purpuratus
    L Gan
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030
    Dev Biol 167:517-28. 1995
    ..The cDNA, termed SpOtx, has a highly conserved orthodenticle homeobox but otherwise diverges in sequence from its fly and mouse ..
  2. ncbi Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene
    C A Mao
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030
    Dev Biol 165:229-42. 1994
    ..core consensus sequence TAATCC, which is capable of binding the sea urchin orthodenticle-related homeobox protein SpOtx. In this report, we extend our analysis of the RSR enhancer by dissecting it into smaller pieces and testing these ..
  3. ncbi Transient appearance of Strongylocentrotus purpuratus Otx in micromere nuclei: cytoplasmic retention of SpOtx possibly mediated through an alpha-actinin interaction
    C K Chuang
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Dev Genet 19:231-7. 1996
    ..Here, we present evidence that an orthodenticle-related protein, SpOtx appears transiently in nuclei of micromeres but not in nuclei of mesomeres and macromeres...
  4. ncbi Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus
    X Li
    Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Dev Biol 187:253-66. 1997
    ..In the sea urchin, Strongylocentrotus purpuratus, an orthodenticle-related protein called SpOtx is believed to direct the activation of the aboral ectoderm-specific Spec2a gene and more generally the ..
  5. ncbi Correct Expression of spec2a in the sea urchin embryo requires both Otx and other cis-regulatory elements
    C H Yuh
    Division of Biology, California Institute of Biology, Pasadena, California 91125, USA
    Dev Biol 232:424-38. 2001
    Strongylocentrotus purpuratus Otx (SpOtx) is required simultaneously in sea urchin development for the activation of endo16 in the vegetal plate and for the activation of spec2a in the aboral ectoderm...
  6. ncbi An otx cis-regulatory module: a key node in the sea urchin endomesoderm gene regulatory network
    Chiou Hwa Yuh
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Dev Biol 269:536-51. 2004
    ..network (GRN) for endomesoderm specification in the sea urchin embryo lies within the regulatory system of the otx gene...