- An ancient role for Gata-1/2/3 and Scl transcription factor homologs in the development of immunocytesCynthia M Solek
Sunnybrook Research Institute and Department of Medical Biophysics, University of Toronto, 2075 Bayview Avenue, Room S 126B, Toronto, Ontario, Canada M4N 3M5
Dev Biol 382:280-92. 2013..These findings provide part of a comparative basis to understand the evolutionary origins and regulatory biology of deuterostome immune cell differentiation in the context of a tractable gene regulatory network model...
- Origins of immunity: transcription factors and homologues of effector genes of the vertebrate immune system expressed in sea urchin coelomocytesZ Pancer
Division of Biology 156 29, California Institute of Technology, Pasadena, CA 91125, USA
Immunogenetics 49:773-86. 1999..We conclude that the vertebrate immune system has evolved by inserting new genes into old gene regulatory networks dedicated to immunity...