dnr

Summary

Gene Symbol: dnr
Description: transcriptional regulator Dnr
Species: Pseudomonas aeruginosa PAO1

Top Publications

  1. pmc Dynamics of the heme-binding bacterial gas-sensing dissimilative nitrate respiration regulator (DNR) and activation barriers for ligand binding and escape
    Laura Lobato
    From the Laboratory for Optics and Biosciences, CNRS, Ecole Polytechnique, 91128 Palaiseau, France, INSERM U696, 91128 Palaiseau, France
    J Biol Chem 289:26514-24. 2014
  2. ncbi Expression of the nir and nor genes for denitrification of Pseudomonas aeruginosa requires a novel CRP/FNR-related transcriptional regulator, DNR, in addition to ANR
    H Arai
    Department of Biotechnology, University of Tokyo, Japan
    FEBS Lett 371:73-6. 1995
  3. ncbi The structural genes for nitric oxide reductase from Pseudomonas aeruginosa
    H Arai
    Department of Biotechnology, University of Tokyo, Japan
    Biochim Biophys Acta 1261:279-84. 1995
  4. doi NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR
    Giorgio Giardina
    Department of Biochemical Sciences A Rossi Fanelli, University of Rome La Sapienza, 00185 Rome, Italy
    J Mol Biol 378:1002-15. 2008
  5. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
  6. doi A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild-type DNR
    Giorgio Giardina
    Department of Biochemical Sciences A Rossi Fanelli, University of Rome La Sapienza, 00185 Rome, Italy
    Proteins 77:174-80. 2009
  7. doi The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli
    Nicoletta Castiglione
    Department of Biochemical Sciences A Rossi Fanelli, Sapienza University of Rome, Rome, Italy
    Microbiology 155:2838-44. 2009

Scientific Experts

  • Hillary S Hayden
  • Giorgio Giardina
  • Nicoletta Castiglione
  • Serena Rinaldo
  • Francesca Cutruzzola
  • Laura Lobato
  • Marten H Vos
  • Latifa Bouzhir-Sima
  • Ursula Liebl
  • Michael T Wilson
  • Taku Yamashita
  • H Arai
  • Manuela Caruso
  • Maurizio Brunori
  • Kenneth A Johnson
  • Adele Di Matteo
  • T Kodama
  • Y Igarashi

Detail Information

Publications7

  1. pmc Dynamics of the heme-binding bacterial gas-sensing dissimilative nitrate respiration regulator (DNR) and activation barriers for ligand binding and escape
    Laura Lobato
    From the Laboratory for Optics and Biosciences, CNRS, Ecole Polytechnique, 91128 Palaiseau, France, INSERM U696, 91128 Palaiseau, France
    J Biol Chem 289:26514-24. 2014
    b>DNR (dissimilative nitrate respiration regulator) is a heme-binding transcription factor that is involved in the regulation of denitrification in Pseudomonas aeruginosa...
  2. ncbi Expression of the nir and nor genes for denitrification of Pseudomonas aeruginosa requires a novel CRP/FNR-related transcriptional regulator, DNR, in addition to ANR
    H Arai
    Department of Biotechnology, University of Tokyo, Japan
    FEBS Lett 371:73-6. 1995
    A gene, designated dnr, was identified in the vicinity of the structural genes for nitrite reductase (nirS) and nitric oxide reductase (norCB), and the gene for activation of the reductases (nirQ) from Pseudomonas aeruginosa...
  3. ncbi The structural genes for nitric oxide reductase from Pseudomonas aeruginosa
    H Arai
    Department of Biotechnology, University of Tokyo, Japan
    Biochim Biophys Acta 1261:279-84. 1995
    ..norC and norB encode cytochrome c (16 kDa) and cytochrome b (52 kDa) subunits of the enzyme, respectively. norCB is immediately followed by an open reading frame encoding a protein of 612 residues...
  4. doi NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR
    Giorgio Giardina
    Department of Biochemical Sciences A Rossi Fanelli, University of Rome La Sapienza, 00185 Rome, Italy
    J Mol Biol 378:1002-15. 2008
    ..denitrification gene clusters by redox signaling, mainly through transcriptional regulators belonging either to the DNR (dissimilative nitrate respiration regulator) or to the NnrR (nitrite and nitric oxide reductase regulator) ..
  5. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
    ..aeruginosa and validates a technology that complements emerging, short-read sequencing methods that are better suited to characterizing single-nucleotide polymorphisms than structural variation...
  6. doi A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild-type DNR
    Giorgio Giardina
    Department of Biochemical Sciences A Rossi Fanelli, University of Rome La Sapienza, 00185 Rome, Italy
    Proteins 77:174-80. 2009
    ..article, we present the crystallographic structure of the wild-type dissimilative nitrate respiration regulator (DNR), a master regulator controlling expression of the denitrification machinery and a putative target for new ..
  7. doi The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli
    Nicoletta Castiglione
    Department of Biochemical Sciences A Rossi Fanelli, Sapienza University of Rome, Rome, Italy
    Microbiology 155:2838-44. 2009
    ..Denitrification is activated by a cascade of redox-sensitive transcription factors, among which is the DNR regulator, sensitive to nitrogen oxides...