- A recent L1 insertion within SPEF2 gene is associated with changes in PRLR expression in sow reproductive organsA Sironen
Agrifood Research Finland, MTT, Biotechnology and Food Research, Genomics, FI 36100, Jokioinen, Finland
Anim Genet 45:500-7. 2014..The causal mutation for this defect is a recent L1 insertion within the SPEF2 gene. In 2001, the insertion frequency was already 0.23...
- An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pigAnu Sironen
MTT Agrifood Research Finland, Animal Production Research, Animal Breeding, FIN 31600, Jokioinen, Finland
Proc Natl Acad Sci U S A 103:5006-11. 2006..2 containing eight annotated genes. Sequence analysis of a candidate gene KPL2 revealed the presence of an inserted retrotransposon within an intron...
- Infertile Finnish Yorkshire boars carry a full-length LINE-1 retrotransposon within the KPL2 geneAnu Sironen
Food and Biotechnology, Animal Genomics, MTT Agrifood Research Finland, 31600, Jokioinen, Finland
Mol Genet Genomics 278:385-91. 2007The KPL2 gene is expressed predominantly in cells with cilia or flagella. We have previously demonstrated that a large intronic insertion in KPL2 is associated with immotile sperm cells and infertility in the domesticated pig (Sus scrofa)...