SPEF2

Summary

Gene Symbol: SPEF2
Description: sperm flagellar 2
Alias: KPL2, sperm flagellar protein 2, KPL2-like protein
Species: pig

Top Publications

  1. doi A recent L1 insertion within SPEF2 gene is associated with changes in PRLR expression in sow reproductive organs
    A Sironen
    Agrifood Research Finland, MTT, Biotechnology and Food Research, Genomics, FI 36100, Jokioinen, Finland
    Anim Genet 45:500-7. 2014
  2. pmc An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pig
    Anu Sironen
    MTT Agrifood Research Finland, Animal Production Research, Animal Breeding, FIN 31600, Jokioinen, Finland
    Proc Natl Acad Sci U S A 103:5006-11. 2006
  3. ncbi Infertile Finnish Yorkshire boars carry a full-length LINE-1 retrotransposon within the KPL2 gene
    Anu Sironen
    Food and Biotechnology, Animal Genomics, MTT Agrifood Research Finland, 31600, Jokioinen, Finland
    Mol Genet Genomics 278:385-91. 2007

Scientific Experts

Detail Information

Publications3

  1. doi A recent L1 insertion within SPEF2 gene is associated with changes in PRLR expression in sow reproductive organs
    A Sironen
    Agrifood Research Finland, MTT, Biotechnology and Food Research, Genomics, FI 36100, Jokioinen, Finland
    Anim Genet 45:500-7. 2014
    ..The causal mutation for this defect is a recent L1 insertion within the SPEF2 gene. In 2001, the insertion frequency was already 0.23...
  2. pmc An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pig
    Anu Sironen
    MTT Agrifood Research Finland, Animal Production Research, Animal Breeding, FIN 31600, Jokioinen, Finland
    Proc Natl Acad Sci U S A 103:5006-11. 2006
    ..2 containing eight annotated genes. Sequence analysis of a candidate gene KPL2 revealed the presence of an inserted retrotransposon within an intron...
  3. ncbi Infertile Finnish Yorkshire boars carry a full-length LINE-1 retrotransposon within the KPL2 gene
    Anu Sironen
    Food and Biotechnology, Animal Genomics, MTT Agrifood Research Finland, 31600, Jokioinen, Finland
    Mol Genet Genomics 278:385-91. 2007
    The KPL2 gene is expressed predominantly in cells with cilia or flagella. We have previously demonstrated that a large intronic insertion in KPL2 is associated with immotile sperm cells and infertility in the domesticated pig (Sus scrofa)...