- Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesisLeslie A Weiss
Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri, USA
J Bacteriol 194:5621-31. 2012..In addition, our data demonstrate that weakening the CarD/RNAP β interaction does not completely phenocopy the depletion of CarD and support the existence of functions for CarD independent of direct RNAP binding...
- CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistenceChristina L Stallings
Immunology Program, Sloan Kettering Institute, New York, NY 10065, USA
Cell 138:146-59. 2009..These findings highlight a distinct molecular mechanism for regulating rRNA transcription in mycobacteria that is critical for M. tuberculosis pathogenesis...