MSMEG_6077

Summary

Gene Symbol: MSMEG_6077
Description: CarD family transcriptional regulator
Species: Mycobacterium smegmatis MC2

Top Publications

  1. pmc Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis
    Leslie A Weiss
    Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri, USA
    J Bacteriol 194:5621-31. 2012
  2. pmc CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence
    Christina L Stallings
    Immunology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Cell 138:146-59. 2009

Detail Information

Publications2

  1. pmc Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis
    Leslie A Weiss
    Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri, USA
    J Bacteriol 194:5621-31. 2012
    ..In addition, our data demonstrate that weakening the CarD/RNAP β interaction does not completely phenocopy the depletion of CarD and support the existence of functions for CarD independent of direct RNAP binding...
  2. pmc CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence
    Christina L Stallings
    Immunology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Cell 138:146-59. 2009
    ..These findings highlight a distinct molecular mechanism for regulating rRNA transcription in mycobacteria that is critical for M. tuberculosis pathogenesis...