S100a6

Summary

Gene Symbol: S100a6
Description: S100 calcium binding protein A6 (calcyclin)
Alias: 2A9, 5B10, CALCYCLIN, Cacy, PRA, protein S100-A6, S100 calcium-binding protein A6, calcium binding protein A6 (calcyclin), prolactin receptor-associated protein
Species: mouse

Top Publications

  1. ncbi Expression of calcium-binding S100 proteins A4 and A6 in regions of the epithelial sac associated with the onset of hair follicle regeneration
    M Ito
    Basic Research Laboratory, Kanebo Ltd, Odawara, Japan
    J Invest Dermatol 116:956-63. 2001
  2. ncbi CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family
    Anna Filipek
    Nencki Institute of Experimental Biology, 3 Pasteur Street, 02 093 Warsaw, Poland
    J Biol Chem 277:28848-52. 2002
  3. ncbi Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
    R Donato
    Section of Anatomy, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Via del Giochetto, C P 81 Succ 3, 06122, Perugia, Italy
    Biochim Biophys Acta 1450:191-231. 1999
  4. ncbi Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin
    A Filipek
    Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland
    J Neurochem 70:1793-8. 1998
  5. pmc A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles
    Michael S Fleming
    Department of Neuroscience and
    J Neurosci 36:10337-10355. 2016
  6. doi S100A6 (calcyclin) is a novel marker of neural stem cells and astrocyte precursors in the subgranular zone of the adult mouse hippocampus
    Jun Yamada
    Department of Developmental Molecular Anatomy, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hippocampus 24:89-101. 2014
  7. ncbi Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1
    W S Moseley
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    Genomics 5:899-905. 1989
  8. pmc S100A6 protein negatively regulates CacyBP/SIP-mediated inhibition of gastric cancer cell proliferation and tumorigenesis
    Xiaoxuan Ning
    Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    PLoS ONE 7:e30185. 2012
  9. pmc Lhx2 maintains stem cell character in hair follicles
    Horace Rhee
    Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, NY 10021
    Science 312:1946-9. 2006
  10. ncbi Organization and chromosomal locations of Rap1a/Krev sequences in the mouse
    N A Dower
    Department of Paediatrics, University of Alberta, Edmonton, Canada
    Mamm Genome 3:162-7. 1992

Scientific Experts

  • Timothy Ravasi
  • Ingo Marenholz
  • Rosario Donato
  • L Konrad
  • Hiroki Yamaguchi
  • Michael S Fleming
  • Jun Yamada
  • Xiaoxuan Ning
  • Rose Anne Romano
  • Lukasz P Słomnicki
  • Bih Rong Wei
  • Florence Quesada Calvo
  • Seiko Shimamoto
  • Horace Rhee
  • Young Kyu Park
  • Louise H Williams
  • Valerie P I Vidal
  • Camilla Bean
  • Ranjoo Hwang
  • B Daub
  • Jian J Li
  • Shin Ichi Abe
  • Qisheng Tu
  • Silvia Arber
  • Tong Li
  • Daniel Ramos
  • Wenqin Luo
  • David A Talmage
  • Anna Filipek
  • Shozo Jinno
  • Yucai Chuai
  • Jie Liang
  • Shiren Sun
  • Yuan Li
  • Xiaoming Wang
  • M Ito
  • Kun Zhang
  • A Filipek
  • Song Liu
  • Wiesława Leśniak
  • M F Seldin
  • Satrajit Sinha
  • Kirsten Smalley
  • Luca Martella
  • Antonella Ravaggi
  • Octavio A Quiñones
  • Louis Wehenkel
  • Marie Alice Meuwis
  • Elio Campagnutta
  • W Gregory Alvord
  • Sergio Pecorelli
  • Jennifer B Edwards
  • Marie Paule Merville
  • Kevin D Woolard
  • Mark M Ross
  • Shelley B Hoover
  • Marianne Fillet
  • Agnes Noel
  • R Mark Simpson
  • Paul K Goldsmith
  • Didier Cataldo
  • Celine Crahay
  • Maud Gueders
  • Emanuel F Petricoin
  • Dominique de Seny
  • Raphael Maree
  • Lance A Liotta
  • Ren Ming Dai
  • Elizabeth I Spehalski
  • Weidong Zhou
  • John I Risinger
  • Francesco Meani
  • Jean Michel Foidart
  • Claudio Belluco
  • Genevieve Paulissen
  • Renaud Louis
  • Natacha Rocks
  • Fumikazu Oohira
  • Masaaki Tokuda
  • B Dragani
  • Maki Takata
  • Hiroshi Tokumitsu
  • K K Lueders
  • Ryoji Kobayashi
  • S F Kingsmore
  • K Ridinger
  • Lisa Polak
  • R L Farnsworth
  • Elaine Fuchs
  • Alberto Pallavicini

Detail Information

Publications51

  1. ncbi Expression of calcium-binding S100 proteins A4 and A6 in regions of the epithelial sac associated with the onset of hair follicle regeneration
    M Ito
    Basic Research Laboratory, Kanebo Ltd, Odawara, Japan
    J Invest Dermatol 116:956-63. 2001
    ..Hair-cycle-dependent expression of S100A4 and S100A6 was found in the epithelial sac regions (bulge area and hair germ) of mouse pelage follicles...
  2. ncbi CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family
    Anna Filipek
    Nencki Institute of Experimental Biology, 3 Pasteur Street, 02 093 Warsaw, Poland
    J Biol Chem 277:28848-52. 2002
    Recently, a human ortholog of mouse calcyclin (S100A6)-binding protein (CacyBP) called SIP (Siah-1-interacting protein) was shown to be a component of a novel ubiquitinylation pathway regulating beta-catenin degradation (Matsuzawa, S...
  3. ncbi Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
    R Donato
    Section of Anatomy, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Via del Giochetto, C P 81 Succ 3, 06122, Perugia, Italy
    Biochim Biophys Acta 1450:191-231. 1999
    ....
  4. ncbi Molecular cloning and expression of a mouse brain cDNA encoding a novel protein target of calcyclin
    A Filipek
    Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland
    J Neurochem 70:1793-8. 1998
    A protein target of mouse calcyclin, p30, which we call calcyclin-binding protein (CacyBP), was identified in mouse brain and Ehrlich ascites tumor (EAT) cells...
  5. pmc A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles
    Michael S Fleming
    Department of Neuroscience and
    J Neurosci 36:10337-10355. 2016
    ..Collectively, our results suggest that a RET-ER81-NRG1 signaling pathway promotes axon communication with nonmyelinating Schwann cells, and that neurons use distinct mechanisms to interact with different types of Schwann cells...
  6. doi S100A6 (calcyclin) is a novel marker of neural stem cells and astrocyte precursors in the subgranular zone of the adult mouse hippocampus
    Jun Yamada
    Department of Developmental Molecular Anatomy, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Hippocampus 24:89-101. 2014
    S100A6 (calcyclin), an EF-hand calcium binding protein, is considered to play various roles in the brain, for example, cell proliferation and differentiation, calcium homeostasis, and neuronal degeneration...
  7. ncbi Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1
    W S Moseley
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    Genomics 5:899-905. 1989
    ..These studies provide a model for examination of specific evolutionary events...
  8. pmc S100A6 protein negatively regulates CacyBP/SIP-mediated inhibition of gastric cancer cell proliferation and tumorigenesis
    Xiaoxuan Ning
    Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    PLoS ONE 7:e30185. 2012
    b>Calcyclin-binding protein (CacyBP/SIP), identified on the basis of its ability to interact with S100 proteins in a calcium-dependent manner, was previously found to inhibit the proliferation and tumorigenesis of gastric cancer cells in ..
  9. pmc Lhx2 maintains stem cell character in hair follicles
    Horace Rhee
    Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, NY 10021
    Science 312:1946-9. 2006
    ..Using gain- and loss-of-function studies, we uncovered a role for Lhx2 in maintaining the growth and undifferentiated properties of hair follicle progenitors...
  10. ncbi Organization and chromosomal locations of Rap1a/Krev sequences in the mouse
    N A Dower
    Department of Paediatrics, University of Alberta, Edmonton, Canada
    Mamm Genome 3:162-7. 1992
    ..Rap1a-rs2 is more distantly related to the gene sequence and is located on Chr 2 near Actc-1...
  11. ncbi Expression of members of the S100 Ca2+-binding protein family in guinea-pig smooth muscle
    B Daub
    Department of Physiology, University of Cologne, Robert Koch Strasse 39, 50931 Cologne, Germany
    Cell Calcium 33:1-10. 2003
    ..Transcripts of cDNA of S100A1, S100A4, S100A6 and S100A10 were amplified from smooth muscle RNA of neonatal and adult urinary bladder, ileum, aorta and from ..
  12. ncbi Calcyclin mediates serum response element (SRE) activation by an osteoblastic extracellular cation-sensing mechanism
    Qisheng Tu
    Center for Bone and Mineral Disorders, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Bone Miner Res 18:1825-33. 2003
    ..Using an expression-cloning strategy, the calcium-binding protein calcyclin was found to mediate the response of MC3T3-E1 osteoblasts to extracellular cations, but not the calcimimetic NPS-..
  13. ncbi Calcyclin, a Ca2+ ion-binding protein, contributes to the anabolic effects of simvastatin on bone
    Ranjoo Hwang
    Departments of Internal Medicine and Anatomy, College of Medicine, Yonsei University, Seoul 120 752, Korea
    J Biol Chem 279:21239-47. 2004
    ..b>Calcyclin was significantly up-regulated by more than 10 times, and annexin I was also up-regulated by simvastatin...
  14. ncbi Probing the S100 protein family through genomic and functional analysis
    Timothy Ravasi
    SRC for Functional and Applied Genomics, University of Queensland, Brisbabe, OLD, Australia
    Genomics 84:10-22. 2004
    ..Evolution of the S100 proteins appears to have occurred in a modular fashion, also seen in other protein families such as the C2H2-type zinc-finger family...
  15. ncbi S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)
    Ingo Marenholz
    Division of Clinical Chemistry and Biochemistry, Department of Pediatrics, University of Zürich Steinwiesstrasse 75, 8032 Zurich, Switzerland
    Biochem Biophys Res Commun 322:1111-22. 2004
    ..An update of the S100 nomenclature is included, because some of the recently identified S100 genes and pseudogenes had to be renamed...
  16. ncbi Gene expression profile analysis of mouse colon embryonic development
    Young Kyu Park
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Genesis 41:1-12. 2005
    ....
  17. ncbi The Ankrd2, Cdkn1c and calcyclin genes are under the control of MyoD during myogenic differentiation
    Camilla Bean
    Dipartimento di Biologia and CRIBI Biotechnology Centre, Universita degli Studi di Padova, 35121 Padova, Italy
    J Mol Biol 349:349-66. 2005
    ..Among these genes, we concentrated our study on the cell cycle regulators Cdkn1c and calcyclin and on the muscle-specific putative myogenic regulator Ankrd2...
  18. ncbi Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment
    Valerie P I Vidal
    Inserm U636, Centre de Biochimie, Faculte des Sciences, Parc Valrose, 06108 Nice, France
    Curr Biol 15:1340-51. 2005
    ..However, factors required for the differentiation of this critical cell lineage remain to be identified. Here, we describe an unexpected role of the HMG-box-containing gene Sox9 in hair development...
  19. ncbi Annexin XI co-localises with calcyclin in proliferating cells of the embryonic mouse testis
    Louise H Williams
    Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Parkville, Australia
    Dev Dyn 234:432-7. 2005
    ..5 dpc, localising to the cytoplasm of the Sertoli cells. Expression of calcyclin (S100a6), shown previously to interact with annexin XI in vitro, was also observed in proliferating cells of the ..
  20. ncbi Calcyclin is differentially expressed in rat testicular cells
    L Konrad
    Department of Anatomy and Cell Biology, Philipps University, Marburg, Germany
    Biochim Biophys Acta 1489:440-4. 1999
    ..One of the cDNA clones isolated showed high homology to calcyclin and a microvascular differentiation gene, CEC5, which was reported to be highly homologous to CASK, a membrane-..
  21. ncbi An update of the S100 nomenclature
    Ingo Marenholz
    Pediatric Pneumology and Immunology, Charité Medical Faculty, Berlin, Germany
    Biochim Biophys Acta 1763:1282-3. 2006
    ..Here we present the official and updated nomenclature of this protein family, approved by the HGNC (HUGO gene nomenclature committee) and ECS (European Calcium Society)...
  22. pmc Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90/Hsp70-organizing protein and kinesin light chain
    Seiko Shimamoto
    Department of Signal Transduction Sciences, Kagawa University Faculty of Medicine, 1750 1 Ikenobe, Kita gun, Kagawa 761 0793, Japan
    J Biol Chem 283:28246-58. 2008
    S100A2 and S100A6 interact with several target proteins in a Ca2+-regulated manner. However, the exact intracellular roles of the S100 proteins are unclear...
  23. doi Biomarker discovery in asthma-related inflammation and remodeling
    Florence Quesada Calvo
    Laboratory of Biology of Tumours and Development, University of Liège and Centre Hospitalier Universitaire CHU Liège, Belgium
    Proteomics 9:2163-70. 2009
    ..We report the identification of different five proteins: found inflammatory zone 1 or RELM alpha (FIZZ-1), calcyclin (S100A6), clara cell secretory protein 10 (CC10), Ubiquitin, and Histone H4.
  24. doi Multistep pathogenesis of leukemia via the MLL-AF4 chimeric gene/Flt3 gene tyrosine kinase domain (TKD) mutation-related enhancement of S100A6 expression
    Hiroki Yamaguchi
    Division of Hematology, Department of Internal Medicine, Nippon Medical School, Bunkyo ku, Tokyo, Japan
    Exp Hematol 37:701-14. 2009
    ....
  25. pmc Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients
    Bih Rong Wei
    Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
    PLoS ONE 4:e7670. 2009
    ..Improved means for early detection and reliable patient monitoring are needed to increase survival...
  26. doi S100A6 (calcyclin) deficiency induces senescence-like changes in cell cycle, morphology and functional characteristics of mouse NIH 3T3 fibroblasts
    Lukasz P Słomnicki
    Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, 3 Pasteur St, 02 093 Warsaw, Poland
    J Cell Biochem 109:576-84. 2010
    S100A6 (calcyclin) is a calcium binding protein with two EF-hand structures expressed mostly in fibroblasts and epithelial cells...
  27. pmc Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha
    Rose Anne Romano
    Department of Biochemistry, Center for Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, NY 14203, USA
    Development 137:1431-9. 2010
    ..Our data provide evidence supporting a role for DeltaNp63alpha in actively suppressing hair follicle differentiation and directing IFE cell lineage commitment...
  28. ncbi Bcl-2 initiates a new category of oncogenes: regulators of cell death
    S J Korsmeyer
    Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, MO 63110
    Blood 80:879-86. 1992
  29. ncbi Chromosomal mapping of the high affinity Fc gamma receptor gene
    R J Oakey
    Department of Medicine, Duke University Medical Center, Durham, NC 27710
    Immunogenetics 35:279-82. 1992
  30. ncbi Characterization of B61, the ligand for the Eck receptor protein-tyrosine kinase
    H Shao
    Department of Pathology, University of Michigan Medical School, Ann Arbor 48109
    J Biol Chem 270:5636-41. 1995
    ..Finally, the gene for B61 was localized to a specific position on mouse chromosome 3 by interspecific back-cross analysis...
  31. ncbi Expression of calcyclin, a calcium-binding protein, in the keratogenous region of growing hair follicles
    L Wood
    Molecular Biology Research, Upjohn Company, Kalamazoo, Michigan 49001
    J Invest Dermatol 96:383-7. 1991
    ..We have isolated a murine cDNA clone, pCAL-F559, for the calcium-binding protein calcyclin by differential screening of a cDNA library made from RNA isolated from hair follicles of 6-d-old mice...
  32. ncbi Related calcium-binding proteins map to the same subregion of chromosome 1q and to an extended region of synteny on mouse chromosome 3
    J R Dorin
    Medical Research Council, Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
    Genomics 8:420-6. 1990
    ..cDNA probes for the related genes calcyclin (CACY) and a mouse placental protein (18A2, suggested name Capl) enabled us to confirm and refine the in situ ..
  33. ncbi Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells
    X J Guo
    Cancer Research Laboratory, University of Western Ontario, London, Canada
    Cell Growth Differ 1:333-8. 1990
    ..Sequence analysis of the 5B10 coding region reveals 94 and 97% amino acid identity to human and rat calcyclin, respectively...
  34. ncbi Calcyclin is a calcium and zinc binding protein
    A Filipek
    Nencki Institute of Experimental Biology, Warsaw, Poland
    FEBS Lett 264:263-6. 1990
    b>Calcyclin, a cell cycle regulated protein, was recently purified from Ehrlich ascites tumour (EAT) cells and shown to be a calcium binding protein. Here we show that calcyclin monomer and dimer also bind zinc ions...
  35. ncbi CD1 defines conserved linkage group border between human chromosomes 1 and mouse chromosomes 1 and 3
    W S Moseley
    Department of Medicine, Duke University Medical Center, Durham, NC 27710
    Immunogenetics 30:378-82. 1989
  36. ncbi Long-range restriction site mapping of a syntenic segment conserved between human chromosome 1 and mouse chromosome 3
    S F Kingsmore
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    Genomics 7:75-83. 1990
    ..Moreover, the data suggest profound conservation of genomic organization during mammalian evolution...
  37. pmc Calcium-binding protein from mouse Ehrlich ascites-tumour cells is homologous to human calcyclin
    J Kuznicki
    Nencki Institute of Experimental Biology, Department of Muscle Biochemistry, Warszawa, Poland
    Biochem J 263:951-6. 1989
    ..A striking homology was found to rat and human calcyclin (a member of the S-100 protein family), which is possibly involved in cell-cycle regulation.
  38. pmc Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements
    D R Edwards
    Mol Cell Biol 5:3280-8. 1985
    ..Sequence analysis of the 49C8 cDNA clone showed greater than 90% homology of a large portion to a consensus rodent B2 repetitive element...
  39. ncbi Genetic mapping of the tumor-associated mucin 1 gene on mouse chromosome 3
    S F Kingsmore
    Department of Medicine, University of Florida, Gainesville 32610, USA
    Mamm Genome 6:378-9. 1995
  40. ncbi Identification and characterization of a sperm peptide antigen recognized by a monoclonal antisperm autoantibody derived from a vasectomized mouse
    S Nakamura
    Department of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan
    Biochem Biophys Res Commun 205:1503-9. 1994
    ..The rabbit antisera raised to the recombinant protein of the 4A11 cDNA gene showed reaction to mouse, rat, hamster and guinea-pig sperm...
  41. ncbi Characterization of the cell-cycle-regulated protein calcyclin from Ehrlich ascites tumor cells. Identification of two binding proteins obtained by Ca2(+)-dependent affinity chromatography
    A Filipek
    Nencki Institute of Experimental Biology, Warsaw, Poland
    Eur J Biochem 195:795-800. 1991
    The nearly complete amino acid sequence obtained for murine calcyclin from Ehrlich ascites tumor cells reveals a very strong similarity with the rat and human sequences previously deduced from corresponding cDNA clones...
  42. ncbi Localization of the osteocalcin gene cluster on mouse chromosome 3
    C Desbois
    Department of Molecular Genetics, University of Texas, M D Anderson Cancer Center, Houston 77030
    Mamm Genome 5:321-2. 1994
  43. ncbi Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain
    S El Mestikawy
    Howard Hughes Medical Institute Research Laboratories, Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710
    J Neurochem 62:445-55. 1994
    ..The gene encoding for XT1 is localized to the mouse chromosome 3 in the vicinity of the locus for the mouse neurological disorder spastic (spa)...
  44. ncbi Coexpression of gap junction proteins in the cumulus-oocyte complex
    G Valdimarsson
    Department of Zoology, University of Western Ontario, London, Canada
    Mol Reprod Dev 36:7-15. 1993
    ..We could find no evidence of the incorporation of the oocyte's store of Cx32 into gap junctions during postfertilization development.(ABSTRACT TRUNCATED AT 250 WORDS)..
  45. ncbi The gene encoding the calcium binding protein calcyclin is expressed at sites of exocytosis in the mouse
    P M Timmons
    Laboratory of Eukaryotic Molecular Genetics, MRC National Institute for Medical Research, Mill Hill, London, England
    J Cell Sci 104:187-96. 1993
    b>Calcyclin is a member of the S100 family of calcium binding proteins. We have found by in situ hybridization that calcyclin transcripts are restricted to specific cell types within a limited number of mouse organs...
  46. ncbi Purification and characterization of mouse decidual calcyclin: a novel stimulator of mouse placental lactogen-II secretion
    G Thordarson
    Department of Biology, Sinsheimer Laboratories, University of California, Santa Cruz 95064
    Endocrinology 129:1257-65. 1991
    ..of this protein showed that it binds calcium and has an amino acid sequence that is highly homologous with calcyclin expressed in mouse embryonic fibroblast cells and with calcyclin from other species...
  47. ncbi Calcyclin in the mouse decidua: expression and effects on placental lactogen secretion
    R L Farnsworth
    Department of Biology, University of California, Santa Cruz, California 95064, USA
    Biol Reprod 59:546-52. 1998
    ..Partial amino acid sequence data suggested that this protein shared sequence identity with mouse calcyclin. In the present study the sequence identity of this protein was determined by sequencing reverse transcription-..
  48. ncbi Clustered organization of S100 genes in human and mouse
    K Ridinger
    Department of Pediatrics, University of Zurich, Switzerland
    Biochim Biophys Acta 1448:254-63. 1998
    ..Since a number of mouse S 100 genes, such as S100A4 and S100A6, have been localized to a syntenic region on mouse chromosome 3, we investigated if the S100 gene cluster exists ..
  49. ncbi The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo
    F Poirier
    Laboratory of Eukaryotic Molecular Genetics, MRC National Institute for Medical Research, Mill Hill, London, UK
    Development 113:1105-14. 1991
    ..After birth, expression of this gene ceases or is dramatically reduced in all tissues...
  50. ncbi About the role of conserved amino acid residues in the calcium-binding site of proteins
    B Dragani
    Arch Biochem Biophys 368:211-3. 1999
  51. ncbi Genomic organization and mapping of the human and mouse neuronal beta2-nicotinic acetylcholine receptor genes
    K K Lueders
    Laboratory of Biochemistry, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mamm Genome 10:900-5. 1999
    ..Our results indicate that this cluster of markers on human Chr 1 is inverted with respect to its orientation on the chromosome compared with markers in the orthologous region of mouse Chr 3...